LOCUS       DAVLBE010000001        91400 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.001, whole genome shotgun sequence.
ACCESSION   DAVLBE010000001 DAVLBE010000000
VERSION     DAVLBE010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 91400)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 91400)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..91400
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.001"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(122..1483)
                     /gene="dnaA"
                     /locus_tag="VXB91_000001"
     CDS             complement(122..1483)
                     /gene="dnaA"
                     /locus_tag="VXB91_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HEV0469528.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYDYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
     gene            complement(1696..2454)
                     /locus_tag="VXB91_000002"
     CDS             complement(1696..2454)
                     /locus_tag="VXB91_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HEV0469529.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLETLLTEKKQKKQQKTNHFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIISFSNQEEYSRIINSLK"
     gene            complement(2512..3693)
                     /locus_tag="VXB91_000003"
     CDS             complement(2512..3693)
                     /locus_tag="VXB91_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HEV0469530.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGEIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLKSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVVVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            3876..4355
                     /gene="rlmH"
                     /locus_tag="VXB91_000004"
     CDS             3876..4355
                     /gene="rlmH"
                     /locus_tag="VXB91_000004"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HEV0469531.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            4399..4472
                     /locus_tag="VXB91_000005"
     tRNA            4399..4472
                     /locus_tag="VXB91_000005"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4433..4435,aa:Arg,seq:tct)
     gene            4637..4762
                     /gene="comC"
                     /locus_tag="VXB91_000006"
     CDS             4637..4762
                     /gene="comC"
                     /locus_tag="VXB91_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HEV0469532.1"
                     /translation="MKNTVKLEQFVALKEKDLQNIKGGEMRISRIILDFLFLRKK"
     gene            4783..6108
                     /locus_tag="VXB91_000007"
     CDS             4783..6108
                     /locus_tag="VXB91_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV0469533.1"
                     /translation="MDLLGFGTVIVHFLIISHSYRLICKGRINRKELYIFGAYTLLTE
                     IVLEFSFYLLYLDKIGIERFLFPLGLYSYFRWMKQYERDRGLFLSLLLSLLYESTHNF
                     LSVTFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDKDYLYPFLKK
                     VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIA
                     LKQKKFEQKHLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRIYNEV
                     LVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIE
                     LLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVMVIQNSCKMTMTPSGDLFA
                     LGFSTKGRNRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE"
     gene            6105..6857
                     /locus_tag="VXB91_000008"
     CDS             6105..6857
                     /locus_tag="VXB91_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0469534.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNIPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQV
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            6909..6980
                     /locus_tag="VXB91_000009"
     tRNA            6909..6980
                     /locus_tag="VXB91_000009"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:6942..6944,aa:Glu,seq:ttc)
     gene            6986..7059
                     /locus_tag="VXB91_000010"
     tRNA            6986..7059
                     /locus_tag="VXB91_000010"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:7020..7022,aa:Asn,seq:gtt)
     gene            complement(7100..7642)
                     /locus_tag="VXB91_000011"
     CDS             complement(7100..7642)
                     /locus_tag="VXB91_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEV0469535.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDVIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSIDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            7821..8588
                     /locus_tag="VXB91_000012"
     CDS             7821..8588
                     /locus_tag="VXB91_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HEV0469536.1"
                     /translation="MIGISLIPDLYNIIFLSSMWDSYGQLSDLPVAVVNNDKEASYNG
                     NTMAIGKDMVSNLKENKTLDFHFVDEEEGKKGLEDGDYYMVVTLPSDLSEKTTTLSNI
                     QSTAAYQSLTSEQQTEISDSVSQNSTDSIQSAQSIVALVQDLQGSLENLQNQSSNLST
                     LKNQSNQVSPITSTSLIGLSSGLTEIQGDVTSKLVPASQSIASGVNAYTTGVDKVSQG
                     ASQLSEKNATLTGSLDKLVSGSNTLTQKSSRLTAGVG"
     gene            8673..9011
                     /locus_tag="VXB91_000013"
     CDS             8673..9011
                     /locus_tag="VXB91_000013"
                     /inference="COORDINATES: protein motif:HMM:TIGR03057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0469537.1"
                     /translation="MADGSGKLAEGGTKLTSGLEDLQTGLASLGQGLGNASDQLKSVS
                     TESKNAEILSNPLNLSKTDNDQVPVNGIAIAPYMISVALFVAAISTNMIFAKLPSGRH
                     PESRWAWLKS"
     gene            9039..9353
                     /locus_tag="VXB91_000014"
     CDS             9039..9353
                     /locus_tag="VXB91_000014"
                     /inference="COORDINATES: protein motif:HMM:TIGR03062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HEV0469538.1"
                     /translation="MAGILVYGGVQLIGLTANHEMRIFILIILTSLVFMSMVTTLATW
                     NSRIGAFFSLILLLLQLASSAGTYPLALTNDFFRSINPWLPMSYSVSGLRQTISINKS
                     FS"
     gene            complement(9454..12006)
                     /locus_tag="VXB91_000015"
     CDS             complement(9454..12006)
                     /locus_tag="VXB91_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HEV0469539.1"
                     /translation="MKSFLKTYRTYFISFIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSSLFYTFTSGLGLNFYALSSYYLGSFLAPLVYFFDLTNMP
                     DAVYLTTLLKFGLIGLSTFFSLNKLFQSIPQTLKLALSTSYALMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLFPFILTILFFTLKSIKFHVKLIYVIFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVTGFL
                     ATIYLKSHYSFLTDLNILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSAYSRDIPAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVNFDY
                     FSPIPYEKTEKIENTNDLISVTSSSNEDAAIQYQIEVPENSQVYLSFINLHFSNDKQK
                     KVDILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTK
                     TFTEAIQKIKEQPVTVSTSKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQ
                     AQTGFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(12068..13690)
                     /locus_tag="VXB91_000016"
     CDS             complement(12068..13690)
                     /locus_tag="VXB91_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0469540.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEDDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
     gene            13896..14921
                     /gene="trpS"
                     /locus_tag="VXB91_000017"
     CDS             13896..14921
                     /gene="trpS"
                     /locus_tag="VXB91_000017"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HEV0469541.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            15073..16551
                     /gene="guaB"
                     /locus_tag="VXB91_000018"
     CDS             15073..16551
                     /gene="guaB"
                     /locus_tag="VXB91_000018"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HEV0469542.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(16602..17699)
                     /gene="recF"
                     /locus_tag="VXB91_000019"
     CDS             complement(16602..17699)
                     /gene="recF"
                     /locus_tag="VXB91_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HEV0469543.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSDQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSRSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKASVNGN"
     gene            complement(17702..18070)
                     /gene="yaaA"
                     /locus_tag="VXB91_000020"
     CDS             complement(17702..18070)
                     /gene="yaaA"
                     /locus_tag="VXB91_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HEV0469544.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SRRGKKLRIGDKVDIPDMNIDILLTQPTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            18229..19479
                     /locus_tag="VXB91_000021"
     CDS             18229..19479
                     /locus_tag="VXB91_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEV0469545.1"
                     /translation="MELVHGISTHFIQSKKFKTNKITVRFTAPLSLDTIAGHMLSASM
                     LETANQMYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPVVVDNGFDPALFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSDLRNRILAETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQPYSNILQEGMVRKNVGQSILELGYHYCSKYGDEQHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSELDLFSGFLRMYAGINRENRNQARKMMNNQLLDL
                     KKGYFTEFELNQTKEMIRWSLLLSQDNQSSLIERAYQNALFGKSSADFKSWIAKLEQI
                     DKDAICRVANNVKLQAIYFMEGIE"
     gene            19476..20759
                     /locus_tag="VXB91_000022"
     CDS             19476..20759
                     /locus_tag="VXB91_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEV0469546.1"
                     /translation="MTKVVFEEKYYPAVKEKVYRTRLANGLTVALLPKKEFKEVYGSV
                     TVQFGSIDTLVTEVDGDVKQYPGGIAHFLEHKLFEREDSSDLMSAFTSLGADSNAFTS
                     FTKTNYLFSATDYFLENLYLLDELVTSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKPTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFGWTSDRFQKCYESGKIDASLSLEVEITSRFHFVMLTMDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            20801..21622
                     /locus_tag="VXB91_000023"
     CDS             20801..21622
                     /locus_tag="VXB91_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0469547.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKISFLPLFYFIFFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            21633..22178
                     /gene="pgsA"
                     /locus_tag="VXB91_000024"
     CDS             21633..22178
                     /gene="pgsA"
                     /locus_tag="VXB91_000024"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HEV0469548.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            22175..23002
                     /locus_tag="VXB91_000025"
     CDS             22175..23002
                     /locus_tag="VXB91_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEV0469549.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALALVGMLDFKKREPARLSGGQKQRVAIAGVVALRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSQNGYDLPENYLTESELEDKLWELL"
     gene            22987..23826
                     /locus_tag="VXB91_000026"
     CDS             22987..23826
                     /locus_tag="VXB91_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEV0469550.1"
                     /translation="MGIALENVNFTYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPSQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPAILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            23819..24613
                     /locus_tag="VXB91_000027"
     CDS             23819..24613
                     /locus_tag="VXB91_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEV0469551.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKAMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            24672..25490
                     /gene="mreC"
                     /locus_tag="VXB91_000028"
     CDS             24672..25490
                     /gene="mreC"
                     /locus_tag="VXB91_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HEV0469552.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKISQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            25490..25984
                     /gene="mreD"
                     /locus_tag="VXB91_000029"
     CDS             25490..25984
                     /gene="mreD"
                     /locus_tag="VXB91_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HEV0469553.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            26078..27256
                     /locus_tag="VXB91_000030"
     CDS             26078..27256
                     /locus_tag="VXB91_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEV0469554.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            27480..28259
                     /gene="rpsB"
                     /locus_tag="VXB91_000031"
     CDS             27480..28259
                     /gene="rpsB"
                     /locus_tag="VXB91_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HEV0469555.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNA"
     gene            28338..29378
                     /locus_tag="VXB91_000032"
     CDS             28338..29378
                     /locus_tag="VXB91_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HEV0469556.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEGGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
     gene            29624..29947
                     /gene="tnpB"
                     /locus_tag="VXB91_000033"
                     /pseudo
     CDS             29624..29947
                     /gene="tnpB"
                     /locus_tag="VXB91_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849103.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
     gene            complement(30102..30389)
                     /locus_tag="VXB91_000034"
                     /pseudo
     CDS             complement(30102..30389)
                     /locus_tag="VXB91_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            30380..30778
                     /locus_tag="VXB91_000035"
     CDS             30380..30778
                     /locus_tag="VXB91_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0469557.1"
                     /translation="MKAPIPKAPLAHSFGSASIIAHTIHQKFNLKVPNYRQEEDWAKM
                     GLPITRKEISNWHIKTSQYYLEPLYNLLRERLLTQPLLHADETSYRVLESDSQLTYYW
                     TFLSGKAEKQGITLYHHVLIDLFISYFNPL"
     gene            complement(30975..31895)
                     /gene="cysK"
                     /locus_tag="VXB91_000036"
     CDS             complement(30975..31895)
                     /gene="cysK"
                     /locus_tag="VXB91_000036"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HEV0469558.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKPGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVFAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYNGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLALAPDNGERYLSTALYEL"
     gene            complement(32180..32815)
                     /locus_tag="VXB91_000037"
     CDS             complement(32180..32815)
                     /locus_tag="VXB91_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HEV0469559.1"
                     /translation="MEFRTIKEDGQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDNGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYAGSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHDLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVPVNLV"
     gene            32871..34169
                     /locus_tag="VXB91_000038"
     CDS             32871..34169
                     /locus_tag="VXB91_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV0469560.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     STILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQAVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPTL
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLSLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLEEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSNLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            34166..34828
                     /locus_tag="VXB91_000039"
     CDS             34166..34828
                     /locus_tag="VXB91_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HEV0469561.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREEGASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            34908..35456
                     /gene="raiA"
                     /locus_tag="VXB91_000040"
     CDS             34908..35456
                     /gene="raiA"
                     /locus_tag="VXB91_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HEV0469562.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNVVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            35592..37565
                     /locus_tag="VXB91_000041"
     CDS             35592..37565
                     /locus_tag="VXB91_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HEV0469563.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTALLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDATSESDISQINSFVANFISEFSEKYMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDQVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDAMGMVTNRSLLILVDHSKTALTLSKEFYDLFTQTIVIDHHRRDQDFP
                     DNAVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGRKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNTQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLTEIVLNEIKEKEKEE"
     gene            37562..38014
                     /gene="rplI"
                     /locus_tag="VXB91_000042"
     CDS             37562..38014
                     /gene="rplI"
                     /locus_tag="VXB91_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HEV0469564.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            38058..39410
                     /gene="dnaB"
                     /locus_tag="VXB91_000043"
     CDS             38058..39410
                     /gene="dnaB"
                     /locus_tag="VXB91_000043"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HEV0469565.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            39412..39678
                     /locus_tag="VXB91_000044"
     CDS             39412..39678
                     /locus_tag="VXB91_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0469566.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            39767..40885
                     /gene="cbpD"
                     /locus_tag="VXB91_000045"
     CDS             39767..40885
                     /gene="cbpD"
                     /locus_tag="VXB91_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HEV0469567.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSGG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEIPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRI
                     IKANTMTGFIHFKDLDGGSVGNSQSSTSTGGTHYFKTKSAIKTEPLVSATVIDYYYPG
                     EKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNYQNQSGNISSYGSNNSSTV
                     GWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQTGWLKENGLWYYLGSSGAM
                     KTGWYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGERV"
     regulatory      40968..41070
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            41141..41431
                     /locus_tag="VXB91_000046"
     CDS             41141..41431
                     /locus_tag="VXB91_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-binding protein"
                     /protein_id="HEV0469568.1"
                     /translation="MKASIALQVLPLAQGIDRIAVIDQVIAYLQTQEVTMVVTPFETV
                     LEGEFDELMRILKEALEVAGQEADNVFANVKINVGEILSIDEKLEKYTETTH"
     gene            41394..42152
                     /locus_tag="VXB91_000047"
     CDS             41394..42152
                     /locus_tag="VXB91_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0469569.1"
                     /translation="MRNLKSILRRHISLLGFLGVLSIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWLNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     NPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRT"
     gene            42190..43197
                     /locus_tag="VXB91_000048"
     CDS             42190..43197
                     /locus_tag="VXB91_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV0469570.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            43197..43925
                     /locus_tag="VXB91_000049"
     CDS             43197..43925
                     /locus_tag="VXB91_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0469571.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPKGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLDK"
     gene            44044..44502
                     /locus_tag="VXB91_000050"
     CDS             44044..44502
                     /locus_tag="VXB91_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HEV0469572.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRELLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQIIQEVDRKGK"
     gene            44504..46936
                     /locus_tag="VXB91_000051"
     CDS             44504..46936
                     /locus_tag="VXB91_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEV0469573.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYEMDRLEEVALELTETDYSQDETFTELPFSRRLQVLFDEAEYVASVVHAKV
                     LGTEHVLYAILHDGNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     TLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKSKHVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSTLKI
                     GVKAGQLKFDIA"
     gene            47257..47910
                     /gene="rr06"
                     /locus_tag="VXB91_000052"
     CDS             47257..47910
                     /gene="rr06"
                     /locus_tag="VXB91_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HEV0469574.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDETTQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDLWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            47907..49247
                     /gene="hk06"
                     /locus_tag="VXB91_000053"
     CDS             47907..49247
                     /gene="hk06"
                     /locus_tag="VXB91_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HEV0469575.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVDVYKEAKNILLLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGEVGKQINGMYEHLLKV
                     IHELESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIA
                     KSINKIDQMSRLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIEN
                     QLTDATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQE
                     LEHLFDIFYHSQIVTDKDESSGLGLYIVNNILESYQMDYSFLPYEHGMEFKISL"
     gene            49330..49857
                     /locus_tag="VXB91_000054"
     CDS             49330..49857
                     /locus_tag="VXB91_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HEV0469576.1"
                     /translation="MVLAIILVTFFIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     MAHIVFYLSCLVEAMVHKTIFDGMGMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYVTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            49936..51852
                     /gene="pspC"
                     /locus_tag="VXB91_000055"
     CDS             49936..51852
                     /gene="pspC"
                     /locus_tag="VXB91_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal surface protein PspC,
                     choline-binding form"
                     /protein_id="HEV0469577.1"
                     /translation="MFASKSERKVHYSIRKFSIGVASVVVASLFLGGVVHAEGVRSEN
                     NPTVTSSGQDISKKYADEVKSHLEKILSEIQTNLDRSKHIKTVNLINKLQDIKRTYLY
                     ELNVLEDKSKAELPSKIKAELDAAFEQFKKDTLPTEPGKKVAEAKKKVEEAEKKAKAQ
                     KEEDYRNYPTITYKTLELEIAESDVKVKEAELELVKKEADESRNEGTINQAKAKVESE
                     QAEATRLKKIKTDREKAEEEAKRRADAKEQDESKRRKSRVKRGDLGEPATPDKKENDA
                     KSSDSSVGEETLPSPSLKPGKKVAEAEKKVEEAEKKAKDQKEEDHRNYPTITYKTLEL
                     EIAESDVEVKKAELELVKEEAKGSRNEEKVKQAKAEVESKKAEATRLEKIKTDRKKAE
                     EAKRKAAEEDKVKEKPAEQPQPAPAPQPEKPAPAPKPENPAEQPKAEKPADQQAEEDY
                     ARRSEEEYNRLTQQQPPKTEKPAQPSTPKTGWKQENGMWYFYNTDGSMATGWLQYNGS
                     WYYLNANGDMATGWFQYNGSWYYLNANGDMATGWLQYNGSWYYLNSNGAMVTGWLQYN
                     GSWYYLNANGSMATDWVKDGDTWYYLEASGAMKASQWFKVSDKWYYVNGSGALAVNTT
                     VDSYRVNANGEWVN"
     gene            complement(52082..53062)
                     /gene="dusB"
                     /locus_tag="VXB91_000056"
     CDS             complement(52082..53062)
                     /gene="dusB"
                     /locus_tag="VXB91_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HEV0469578.1"
                     /translation="MTNLNTPFMIGNVEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLIN
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKA"
     gene            complement(53049..53921)
                     /gene="hslO"
                     /locus_tag="VXB91_000057"
     CDS             complement(53049..53921)
                     /gene="hslO"
                     /locus_tag="VXB91_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HEV0469579.1"
                     /translation="MDKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGAGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKVAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGVEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            54086..55513
                     /locus_tag="VXB91_000058"
     CDS             54086..55513
                     /locus_tag="VXB91_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0469580.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELAIHSEDENLRLSIGAATKGRDIRSLFLESAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIRYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSVGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPAFQQGTDLDKKILWEWLQLIEYMAENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKE
                     QTPVYYLKNDLDMEDLVAIRQLLFT"
     gene            55672..57180
                     /gene="glpK"
                     /locus_tag="VXB91_000059"
     CDS             55672..57180
                     /gene="glpK"
                     /locus_tag="VXB91_000059"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HEV0469581.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQVDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEVDD"
     gene            57222..59048
                     /gene="glpO"
                     /locus_tag="VXB91_000060"
     CDS             57222..59048
                     /gene="glpO"
                     /locus_tag="VXB91_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HEV0469582.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTPTANKVLSKKEVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKYLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELALSPVDFLLRRTNHMLFMRDSLD
                     SIVEPVLDEMGRFYDWTEEEKATYRADVEAALANNDLAELKN"
     gene            59118..59822
                     /locus_tag="VXB91_000061"
     CDS             59118..59822
                     /locus_tag="VXB91_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEV0469583.1"
                     /translation="MMNELFGEFLGTLILILLGNGVVAGVVLPKTKSNSSGWIVITMG
                     WGIAVAVAVFVSGKLSPAHLNPAVTVGVALKGDLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEAEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPIPNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            60119..60322
                     /locus_tag="VXB91_000062"
     CDS             60119..60322
                     /locus_tag="VXB91_000062"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0469584.1"
                     /translation="MPKWSNPDYVNELDPKIVDMLVEFHKSQGTLETPEAQAEIAQKR
                     EEIEQRRAELEDKKQELLNRLNK"
     gene            complement(60409..61017)
                     /locus_tag="VXB91_000063"
     CDS             complement(60409..61017)
                     /locus_tag="VXB91_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0469585.1"
                     /translation="MSSISPSLVVFADDSLSANSKVVSGEAQFENGSSVRFGDTQVNI
                     LSDEVLEVVNPDGSVDTIERRADGVYINGAFYMAYQKNEIDLNISFRSYDPNVWNYVN
                     TIHGNKQANTFANFMTGAGISYMIGRIGALLGGPWGAIIGGAYFGIQAYQSYLDSQSP
                     YPYYITSTYIHVAQRKWKFITEYYRNSNYTGYVKTVTTYVNF"
     gene            62151..63428
                     /gene="ltrA"
                     /locus_tag="VXB91_000064"
     CDS             62151..63428
                     /gene="ltrA"
                     /locus_tag="VXB91_000064"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HEV0469586.1"
                     /translation="MSKLLDKILSRENMLEAYNQVKSNKGSAGIDGMTIEEMDNYLRQ
                     NWRLTKELIKQRKYKPQPVLKVEIPKPDGGIRQLGISTVMDRMIQQAIVQVMSPICEP
                     HFSDTSYGFRPNRSCEKAIMKLLEYLNDGYEWIVDIDLEKFFDTVPQDRLMSLVHNII
                     EDGDTESLIRKYLHSGVIINGQRYKTLVGTPQGGNLSPLLSNIMLNELDKELEKRGLR
                     FVRYADDCVITVVSEAAAKRMMYSVSRFIEKRLGLKANMTKTKITRPRELKYLGFGFW
                     KSSDGWKSRPHQDSVRRFKLKLKKLTQRKWSIDLTRRIEQLNLSIRGWINYFSLGNMK
                     SIVASIDERLRTRLRVIIWKQWKKKSRRLWGLLKLGVPKWIADKVSGWGDHYQLVAQK
                     SVLKRAISKPVLEKRGLVSCLDYYLERHALKVS"
     gene            63884..65062
                     /locus_tag="VXB91_000065"
     CDS             63884..65062
                     /locus_tag="VXB91_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV0469587.1"
                     /translation="MSNSFVKLLVSQLFANLADIFFRVTIIANIYIISKSVIATSLVP
                     ILIGISSFVASLLVPLVTKRLALNRVLSLSQFGKTILLAILVGMFTVMQSVAPLVTYL
                     FVVAISILDGFAAPVSYAIVPRYATDLGKANSALSMTGEAVQLIGWGLGGLLFATIGL
                     LPTTFIILVLYIISSFLMLFLPNAEVEVLESETNLEILLKGWKLVARNPRLRLFVSAN
                     LLEIFSNTIWVSSIILVFVTELLNKTESYWGYSNTAYSIGIIISGLIAFRLSEKFLAA
                     KWESILFPLVAMAIVTLTILYFPNAQMFLLFSALVGMLSQLKEVPESVFLQETVEENH
                     LVNVYSVLEVISTLAFSVFVLLMSYITESFGISISFWLSAICLMIEAILIYIRRDYFK
                     "
     gene            65376..65507
                     /locus_tag="VXB91_000066"
     CDS             65376..65507
                     /locus_tag="VXB91_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HEV0469588.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            65528..67067
                     /gene="dltA"
                     /locus_tag="VXB91_000067"
                     /pseudo
     CDS             65528..67067
                     /gene="dltA"
                     /locus_tag="VXB91_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
     gene            67064..68308
                     /gene="dltB"
                     /locus_tag="VXB91_000068"
     CDS             67064..68308
                     /gene="dltB"
                     /locus_tag="VXB91_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HEV0469589.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIIIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQTIPERDELMDMLDESVRYIMRGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQLLGMVVT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            68322..68561
                     /gene="dltC"
                     /locus_tag="VXB91_000069"
     CDS             68322..68561
                     /gene="dltC"
                     /locus_tag="VXB91_000069"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HEV0469590.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            68554..69822
                     /gene="dltD"
                     /locus_tag="VXB91_000070"
     CDS             68554..69822
                     /gene="dltD"
                     /locus_tag="VXB91_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HEV0469591.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLQQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKEELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            69977..70417
                     /gene="adcR"
                     /locus_tag="VXB91_000071"
     CDS             69977..70417
                     /gene="adcR"
                     /locus_tag="VXB91_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HEV0469592.1"
                     /translation="MRQLAKDINAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            70417..71121
                     /locus_tag="VXB91_000072"
     CDS             70417..71121
                     /locus_tag="VXB91_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEV0469593.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYCVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNAHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVGHA"
     gene            71114..71920
                     /locus_tag="VXB91_000073"
     CDS             71114..71920
                     /locus_tag="VXB91_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEV0469594.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGKSSSSMSLDQYLFGSIVTISEEQVISLFVIAVVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            71930..73435
                     /gene="adcA"
                     /locus_tag="VXB91_000074"
     CDS             71930..73435
                     /gene="adcA"
                     /locus_tag="VXB91_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HEV0469595.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGEEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKETFEKNAAAYIEKLQALDKAYTEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISVMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNVAPVKAEHFHIFFGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLAH"
     gene            complement(74606..75379)
                     /locus_tag="VXB91_000075"
     CDS             complement(74606..75379)
                     /locus_tag="VXB91_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV0469596.1"
                     /translation="MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLE
                     NQGLIKRKHGYVTLSSMNTIELSHQIREGESTRQKRLIASLAKDFIRSGMCVYLDSST
                     TVYELCPYLSELDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKE
                     NSLLDHFNIDLAFCSARGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTG
                     FFKINPLSKYTTFISDTVPDQKLLDAVELFDGEWVSDIQ"
     gene            75555..76958
                     /locus_tag="VXB91_000076"
     CDS             75555..76958
                     /locus_tag="VXB91_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HEV0469597.1"
                     /translation="MEAVLAIDLGATSGRAIVGYLSENKLVMEEINRFSNLPIRVKGH
                     LSWDIDFLLAKILESIRLANTSYKILSIGIDTWGVDFGLIDNEGKLLSQPVHYRDERT
                     KGVLKEISEMTELEKLYSETGNQIMEINTLFQLFKARQESPDSFYKTNKILLMPDLFN
                     YLLTGKFATEKSIASTTQLFDPRSQNWNQNILKLFELDSSLLPEIVSEGNVLGRIKKE
                     YGLGDIPVVNVCSHDTASAIVSVPKTEGSLFISSGTWSLVGVELTSPILTTESFSYGF
                     TNEVGKDGEITFLKNCTGLWIIEELRRSFERRGKAYSFDDIRTMVEKEKENLPLIDTE
                     STEFATESDMHKTLTEYLAYHHETREWTDGQLFKIVYESLAETYRKAIELLEELTHKV
                     YKRIYVIGGGARASYFNQMIADRTGKEVLTGSTEGTAVGNIVVQLIAMGQLKGMEEAH
                     HVIEEFLQLESYYSQKN"
     gene            77073..77711
                     /locus_tag="VXB91_000077"
     CDS             77073..77711
                     /locus_tag="VXB91_000077"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001286141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HEV0469598.1"
                     /translation="MSDVKQELIKYGKKLVETDLTKGTGGNLSVFDREKQLMAITPSG
                     IDFFEIKESDIVVMDINGNVVEGERLPSSEWYMHLIQYQTRDDIDAIIHAHTTYATVL
                     ACLREPLPASHYMIAVAGKDVRVAEYATYGTKELAVNAAKAMEGRRAVLLANHGILAG
                     AQNLLNAFNIVEEVEYCAKIYCLAKNFGEPVVLPDEEMDLMAEKFKTYGQRK"
     gene            77723..78163
                     /locus_tag="VXB91_000078"
     CDS             77723..78163
                     /locus_tag="VXB91_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RbsD/FucU family protein"
                     /protein_id="HEV0469599.1"
                     /translation="MLKHIPKNISPDLLKTLMEMGHGDEIVLADANYPSASCANKLIR
                     CDGVNIPELLDSILYLMPLDSYVDSSIQFMNVVSGDDIPKIWGTYRQMIEGHGTDLKT
                     ITYLRREDFYERSKKAYAIVATGETSLYANIILKKGVVVERENV"
     gene            78156..78587
                     /locus_tag="VXB91_000079"
     CDS             78156..78587
                     /locus_tag="VXB91_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000483177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0469600.1"
                     /translation="MFNRGILVASHGNFASGALMTAEMFVGETTNDRVRTLGLMPGEN
                     IVEFEHYFKNQVNELLDSNQEVIVLTDLIGGSPNNVALSRFLNLDSVDIVTGFNIPLL
                     VELISSYDSKINLEEIVQNAQNSLFNVKQQLNVEEEEDLCL"
     gene            78578..79048
                     /locus_tag="VXB91_000080"
     CDS             78578..79048
                     /locus_tag="VXB91_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000020992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0469601.1"
                     /translation="MSIEFVRIDDRLVHGQVVTTWLKKYDIEQVIIVNDRISEDKTRQ
                     SILKISAPVGLKIVFFSVKRFVEVLNSVPIKKRTMLIYTNPKDVYDSIEGNLKLEYLN
                     VGQMSKTEENEKVTGGVALGEEDKYYFKKIVDKGTRVEIQMVPNDKVTMLEKFL"
     gene            79073..79846
                     /locus_tag="VXB91_000081"
     CDS             79073..79846
                     /locus_tag="VXB91_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000899624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEV0469602.1"
                     /translation="MLFTQALLVTLVGIIATIDYNGPLFMIHRPLVTSAMVGLVLGDF
                     TQGVLIGSALELTWLGVTGIGGYTPPDTISGAIIGTAFGILSGQGETAGIAIAVPIAV
                     ATQQLDVLAKTLDVYFVKKADNDAKNGDYSKIGFYHYSSLVLITLFKIVPIFLAIMLG
                     GEYVADLFAKVPPIVMQGLNSAGALLPSIGFGMLLNMMLKKNMWVFLLIGFICSVYGG
                     MSTIGISLVGIAVAYFYDMIGSKPQETTSSSDVEEDLDL"
     gene            79843..80643
                     /locus_tag="VXB91_000082"
     CDS             79843..80643
                     /locus_tag="VXB91_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV0469603.1"
                     /translation="MMNNKVTKVELKKVFKRSFMYGSSWNYERMQNLGFLYTILPVLK
                     KLYPDKDSASPAMKRHLEFFNTHQTAAPFILGVTSAMEEQEGNEGAASITGIKVGLMG
                     PLAGLGDSLFWLTLVPICFSIGASYSKDGGALGIFIALILFNIINIPVKYFGLKYGYT
                     KGSSLIQENNTKGTLNRVTSMATALGLVLVGGLIPSMVGINFGLEFKQGELVISVQEM
                     ITKLIPGFIPMALTLLMCKLIRKGKNPVVLIFSVMAIGVILVVLGILK"
     gene            80702..82996
                     /locus_tag="VXB91_000083"
     CDS             80702..82996
                     /locus_tag="VXB91_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HEV0469604.1"
                     /translation="MKLWYKKAAANWNEALPIGNGHLGGMIYGSATKECIQLNDETIW
                     YRGKSDRNNPDSLLHLKKIREYLLDGEIQKAEELIKLTMFATPRDQSHYELLGELCIE
                     HIDIQSCALSLYERELDLDTAISNVVFEPNSCNLQIKREYFTSFNKNILCCRIVSSVQ
                     NTLNLNINLGRNKRFNDEVSKLDSSTILMSASAGGRKGVQFKVVCHSKVTDGEVSVLG
                     ETIVIRNATEVFLYLKSMTDYWGNIDISSLQGEFSSIDYFTEKDEHVKKYQEQFNRVD
                     FKLDYSKGCLSIPTNLLLENTKKYSNYLTNLLFHYGRYLLISSSQPNGLPANLQGIWC
                     DELNPIWGSKYTININTQMNYWMVGPCDLPEVEYPLFDMLERMREPGRLTAKKMYGAR
                     GFTAHHNTDGFGDTAPQSHAMGAAIWVLTIPWLCTHIWEHYLYFQDERILTEHFEMIK
                     EAFLFFEDYLFEVDGYLMTGPSVSPENKYRLKNGIEGNACLSSTIDNQILRYFCDSCI
                     GIAKQLGDNSDFISRVKELKKKLPRTKIGSNGQIQEWLEDYEEVEPGHRHISPLFGLY
                     PYNEIDIHKTPELAEAAKITINRRLSNANFLSSQDREQAINNWLVSGLHASTQTGWSA
                     AWLIHFFARLYQGEPAYNQINGLLNNATLGNLFLDHPPFQIDGNLGLVSGICELLVQS
                     HHNWLSLIPALPSAWSEGEVKGFRVRGGYKVSFAWKNGDITFLKLEGGNKDQKVRVRI
                     YGKNTDVQNIELVFNSEKIIELNF"
     gene            83006..86122
                     /locus_tag="VXB91_000084"
     CDS             83006..86122
                     /locus_tag="VXB91_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HEV0469605.1"
                     /translation="MNKEKIKRKLITILFVCIGMLCFGLLAGVKADNRVQMRTTINNE
                     SPLLLSPLYGNDNGNGLWWGNTLKGAWEAIPEDVKPYAAIELHPAKVCKPTSCIPRDT
                     KELREWYVKMLEEAQSLNIPVFLVIMSAGERNTVPPEWLDEQFQKYSVLKGVLNIENY
                     WIYNNQLAPHSAKYLEVCAKYGAHFIWHDHEKWFWETIMNDPTFFEASQKYHKNLVLA
                     TKNTPIRDDAGTDSIVSGFWLSGLCDNWGSSTDTWKWWEKHYTNTFETGRARDMRSYA
                     SEPESMIAMEMMNVYTGGGTVYNFECAAYTFMTNDVPTPAFTKGIIPFFRHAIQNPAP
                     SKEEVVNRTKAVFWNGEGRISSLNGFYQGLYSNDETMPLYNNGRYHILPVIHEKIDKE
                     KISSIFPNAKILTKNSEELSSKVNYLNSLYPKLYEGDGYAQRVGNSWYIYNSNANINK
                     NQQVMLPMYTNNTKSLSLDLTPHTYAVVKENPNNLHILLNNYRTDKTAMWALSGNFDA
                     SKSWKKEELELANWISKNYSINPVDNDFRTTTLTLKGHTGHKPQINISGDKNHYTYTE
                     NWDENTHVYTITVNHNGMVEMSINTEGTGPVPFPTPDKFNDGNLNIAYAKPTTQSSVD
                     YNGDPNRAVDGNRNGNFNSGSVTHTRADNPSWWEVDLKKMDKVGLVKIYNRTDAETQR
                     LSNFDVILYDNNRNEVAKKHVNNLSGESVSLDFKEKGARYIKVKLLTSGVPLSLAEVE
                     VFRESDGKQSEEDIDKITEDKVVSTNKVATQSSTNYEGVAALAVDGNKDGDYGHHSVT
                     HTKADSNAWWQVDLGEEFTVSKVDIYNRTDAEPQRLSNFDVIFLSSSGEEVFRRHFDK
                     VVDGLLSLKVPSVGAKLVKIELKSAAIPLSLAEVEVYGSKRTPKKLSNIALTKETRQS
                     STDYNGFSRLAVDGNKNGDYGHHSVTHTKGDSPSWWEIDLAQTEELEKLIIYNRTDAE
                     IQRLSNFDIIIYDSNNHEVFKQHIDSLESNNLSIDLKGLKGKKVRISLRNAGIPLSLA
                     EVEVYTYK"
     gene            86179..87945
                     /locus_tag="VXB91_000085"
     CDS             86179..87945
                     /locus_tag="VXB91_000085"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HEV0469606.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIP
                     HAIWGFNGTERPGAVYLAAVLASHAQKGIPAFGIYGRDVQEANDTDIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRG
                     IYDPEEFERAMVWVKEHIKEGVDRNREDLILSKEEKEKQWEFVIKMFMIGRDLMVGNP
                     RLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVERVTGYTLEGRAAAGFLHLINSG
                     SCTLDGTGQATRDGKPVMKPFWELDESEVQAMLENTDFPPANREYFRGGGFSTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDSGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYRACQLLGPLHK"
     gene            88091..89242
                     /locus_tag="VXB91_000086"
     CDS             88091..89242
                     /locus_tag="VXB91_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HEV0469607.1"
                     /translation="MAIFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKTLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHGCDFIISLGGGSPQDAA
                     SCISIMATNGGKPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPKGLTAATGMDALTHAVEALVTPGTYDVTKKLSIGAI
                     ELIKEYLPRAVENGHDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIERENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIAEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            89387..90271
                     /locus_tag="VXB91_000087"
     CDS             89387..90271
                     /locus_tag="VXB91_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEV0469608.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            complement(90389..90466)
                     /locus_tag="VXB91_000088"
                     /pseudo
     CDS             complement(90389..90466)
                     /locus_tag="VXB91_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            90670..90921
                     /locus_tag="VXB91_000089"
     CDS             90670..90921
                     /locus_tag="VXB91_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEV0469609.1"
                     /translation="MKEFQFERKQRFSLRKYAIGACSVLLGTSLFFAGMGAQPVQDTE
                     TSSALISSHYLDEQDLSEKLKSELQWFELENKLLNLWEH"
     gene            90909..91199
                     /locus_tag="VXB91_000090"
     CDS             90909..91199
                     /locus_tag="VXB91_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0469610.1"
                     /translation="MGALGYYEGFVPYVSNQYQNQAEEEYKPLSDKYIFEKILGKTYA
                     AFKKDQINERVEKLGKLKPITINYNGKSEVIDSKEKLQELMNKAVKDEVAQI"
BASE COUNT        28662 a        15242 c        19485 g        28011 t
ORIGIN      
        1 atagtaataa tagagtctgt gaaatctgtg gaaaacagcc tttaaacaag tcatatcaag
       61 ttttttagct tgtttaaaaa atgtggataa aaaagataaa aaactaaaag ttatccacaa
      121 attatttgat tttctttttg attgattcaa tttctaaacg taaattatcg tcttgatcaa
      181 tcaaagattt tattttggca tgggcatgaa tgactgtggt atgatctttt cccccaaatt
      241 ccttcccaat ttttggaaga ctattatctg ttagttctct agataaatac atggctactt
      301 gacgggccaa aacaatattt tgaaggcgtc tacttccctt catttctttg atactaacac
      361 cataaaagtt accaacttca gtttggattt tatcaattgg gatgacgagc atttggctaa
      421 catcttgttt gcgggctcta atggcttctg cagcaatatc aatagtgata tccttgattt
      481 tttttactct ggcaattaaa gtgatgtcgt tgatggctcc ctcaagatct cgaacatttg
      541 aatcaaattg cccagctagg tattctagag tatcactttg gaaattgtag cctaaatgtt
      601 ccgtcttact ttgtaaaatg gcaatacgtg tttcaaagtc agggggtgtg atagtttgtg
      661 tcaatcccca actaaaacgc gtgacaagcc tctcctcgag cccttctaga tgttttggac
      721 tacgatcact cgttaggaca atctgttttt gcttgtcatg aagggcgtta aaggtattga
      781 aaaattcttc ctgagttgcg actttttttc cgctgagtga ctgtatatca tcgattaaca
      841 aaagatcaag actacgatag gtctttttaa acttttccat ttccccaagt cttaggtgat
      901 caagaaagtc attaataaag ctttcggcag ggatatattt aacacgcgca ttaggaatat
      961 tttttagaat ttcatttcca atagcgttta ataagtgagt cttaccaagg cctggtcctc
     1021 catagataaa aagagggtta taggtcagag ccaaatcttc agagacagct aaagcggctg
     1081 atacagccca aacatttcca tccccttgaa taaagttatc aaaggtatac ttttctttta
     1141 atcccgtatc tgaataagga atagatacta actttggact atagtcataa agagttaaat
     1201 ttgtagcttc ttcaacttgt gagctagtcg tatcttgagg tttggtgaaa atatagtggg
     1261 gagttatttc agcgtcataa atttcaaaac cagctactac aataatatct tttagttgtt
     1321 tttcccagac catttccatt tcagagcgag gtagaaatat agtggcaaca ttttcctcta
     1381 ccttgatgag ttcagcttga atagcataga aatcatacat ggatcgagtc agtctttctt
     1441 gtgcaaattc taatatacga ttccaaaatt gtttttcttt caatcctttc tcctccttta
     1501 ctatttaaaa gtttaatact agagatattt taccatagat agcaagaatt ttccacaagc
     1561 tgtgaaaaat aatccacaat gttaccaaac tttatccaca ggttggggat aaaagaagaa
     1621 attattgatt tattaagctt tttatcgaaa aacatagtgg ataaccttgt gagataaaaa
     1681 aataaaagaa cagccttatt tcaggctgtt gataattcta ctatattctt cttgatttga
     1741 aaaagaaata atgatttttc cactgtcttt tttagatagt ttaatttcta catctaatcc
     1801 gagtagtttt cttaactgtt tttcttcatt ttgtatgaaa tgattagttt tttgctgttt
     1861 cttttgtttt ttctctgtca gaagagtttc taacttcctt acagaaatat cttcttctat
     1921 aatccgttga aagaaatagt cttgttgttc cttatttaac ccaactaggg aacgcgcatg
     1981 ggcttgtgat agtttgccat tttctacttc tgagagaatc tgttctggca aggaaagtaa
     2041 acgaatggag ttgctgatat atggacgaga cttgcccatc ttatctgcaa tttcagcatg
     2101 ggtgaatcct ttctctacga gagattcata ggcgcgtgct tcttctattg ggtttaaatt
     2161 ttctctctgt aaattttcaa taatggactg gaccatcatc tcttggtctg aaatctgttt
     2221 aacaacagct gggatagacc gtagaccagc taaaagtgaa gcccgatagc gtctctctcc
     2281 tgcaaggatt tcataaccaa taacaggaga ttgacgaaca ataatcggtt gaatgacccc
     2341 attttctttg atagactgtg ctagttcatc tagcttttct ctatcaaatt cttttcgggg
     2401 ttgataggga tttttttgta tatctgtgat agaaatcatt tcaaattttt ccatgattct
     2461 acactaacac atcttttctc ttatgtaaag ctttctttac atagatgtca attaagattc
     2521 taaatcacct gaactcttgt taagtttgat agaggtagtt tcttctttcc cgttacgata
     2581 gtaggttatc ttaatggtgt ctccgataga atggttgtaa agagcacttt gtaagtctgt
     2641 tgatgaagca atctctttgt catctacttt tgtaattaca tcgtattttt caaggtgacc
     2701 attggcaggc atattacttt gtaccgaacg aacaactaca ccagatgtaa cattacttgg
     2761 aatattgagt cttctgatgt cgcttgtact cacattagat aaattaacca tctggattcc
     2821 caaagctgga cgcgtcactt ttccgttttt ttctaactgt tcaataatat tgatagcatc
     2881 atttgcagga attgcgaaac caagaccttc tacagatgtt cctccatttg tagcaatttt
     2941 acttgaggta attccgataa cctgcccttg aatattgatc agtgggccgc cagagttacc
     3001 tgggttaata gcagtatcag tttggatggc ttttgtagaa atagcttgtc catcttccga
     3061 ttttaaggat acatttctat tgagactgga tacgatacct tgagtgacag tatttgcata
     3121 ttcagaacct aacgggctac cgatggcaat agcagtttct cctacagtta acttactaga
     3181 atcaccaaac tcagctactg ttgtcacttt ttctgaagag atttttacga cagcaatatc
     3241 agagaaagtg tcagctccga caatttctcc aggtacttta gtcccatctg acaatcgaat
     3301 atctactttg ctggcgccat ttataacgtg attgttggtg acgatgtaag cttctttatc
     3361 attcttttta taaataactc cagatccttc actagagatt cgctgagaat ctgtgtcagt
     3421 atcatcattg ccaaatacgc tattttgtct gtttgccgaa taagtaataa cagaaacaac
     3481 agcatctttt actttgttaa cagcctgtgt tgttgaattt tcgttcttat aggcagtttg
     3541 tgtaatagta ctattattgt tagagttgtt tacactactt ttttgagtta gttgagttat
     3601 tgaaaaacta cccaaggctc cactaaaaaa gctaatgacg ataacgacta ataattgaaa
     3661 ccattttttg taaaatgttt ttagatgttt catatttgcc tccatatgtt tgaattactg
     3721 aaagtataaa ctgactagct taattataac ttaaacacaa aagttttaca caaactgtgg
     3781 ataactcttt tgaaactgtg attttcttaa ttgaaatcta ttttttattt tgtgaataag
     3841 atgtgaaaaa atagagaata tgttagaata gagtcatgaa aattaaagtt gtaacagttg
     3901 ggaaactgaa agaaaagtat ttaaaagatg gtatcgcaga gtattcaaaa cgaatttcta
     3961 gatttgctaa gtttgaaatg attgagttat cagatgaaaa aacaccagat aaggccagtg
     4021 aatcagaaaa tcaaaagatt ttagaaatag aaggtcagag aattttatca aaaattgctg
     4081 accgtgattt cgttattgtg ttagccattg aagggaaaac tttcttctca gaagaattta
     4141 gtaagcagtt agaagaaact tctataaaag gattttctac tcttactttt attattgggg
     4201 gaagtttagg attgtcatca tctgtaaaaa atagagccaa tctttctgtc agttttggtc
     4261 gcctaacctt gcctcatcag ttaatgagac tagttcttgt tgaacaaatc tatcgcgctt
     4321 ttacgattca gcagggattc ccctaccata aatagaaaat tgacttttaa ttgaattttt
     4381 ggtagaataa ttgtgttagg tctcatagct cagctggata gagcattcgc cttctaagcg
     4441 aacggtcgca ggttcgaatc ctgctgggat caatataata gcaaagctgg gaattttccc
     4501 ggcttttttc ttaaaaaagt acactttggg agaaaaaaat gacagttgag agaattttat
     4561 ctaaagtgaa attccatttt gtataatggt ttttgtaagt tagcttacaa gaaaaaacat
     4621 tttaggagat tttattatga aaaacacagt taaattggaa cagtttgtag ctttgaagga
     4681 aaaagactta caaaatatta aaggtgggga gatgaggatt tcaagaatca tccttgattt
     4741 tcttttccta cgaaaaaagt aatgaaataa ggagaaagag taatggattt acttggattt
     4801 gggacagtta ttgttcattt tttaattatt agtcacagtt accgtttaat ttgtaaaggt
     4861 cgaataaata gaaaagaatt atacattttt ggtgcttata cattactaac tgaaatagta
     4921 cttgaatttt ccttttatct tctatattta gataaaatag ggattgaaag atttttattt
     4981 cctttgggct tatattccta ttttcgatgg atgaaacagt atgagaggga tagaggacta
     5041 ttcctaagtt tactactatc tcttttatat gagagcactc ataactttct gtccgtaact
     5101 ttctcctcta taacaggaga taattttgtt ttacaatatc atttcccatt ctttttcgtt
     5161 gtgacggtgt taacctattt tgttacatta aaaatcattt attatttcca tttggaacta
     5221 gcctattttg acaaggacta cctttatcct ttcttgaaaa aagtattttt tgctttacta
     5281 ttgctacata ttgtatcttt cgtttcagat atggtaagta cgattaaaca tttgaatagt
     5341 tttggaagta ttttgtcatc tattgtcttt atctctctcc ttttgacctt ctttgcaatg
     5401 aattctcata aagttcaaat ggagaaagag attgctttga agcagaagaa atttgaacag
     5461 aaacatttac agaattacac agatgaaatt gttggtctgt ataatgaaat ccgtggtttt
     5521 cgacatgatt atgctggaat gcttgtcagc atgcagatgg caattgacag tggtaattta
     5581 caggaaattg acagaattta caatgaagtt ttagtcaaag caaatcataa attgcgttca
     5641 gataagtaca cttactttga tttgaacaac atagaagact cagctttacg aagtttggtt
     5701 gctcagtcaa ttgtctatgc tcgaaataat ggtgtagagt ttacactgga agtaaaagat
     5761 acgattacca agcttccaat tgaactattg gatttggttc gtatcatgag cgttttattg
     5821 aataatgctg tcgaaggatc ggctgatagc tataaaaagc agatggaagt agcagttatt
     5881 aagatggaaa ctgaaacagt tatggtgatt cagaattcat gtaaaatgac gatgactcct
     5941 tcaggagatc tatttgcctt aggattctcc actaagggaa gaaatcgcgg agtcggatta
     6001 aataatgtga aagaactact agataagtac aacaatatta ttttagaaac agagatggaa
     6061 ggcagtacat ttagacaaat cattagattt aagagggaat ttgaatgaaa gttttaattt
     6121 tagaagatgt tattgaacat caagtgagac tagagagaat attggatgaa atttcgaaag
     6181 aatcgaatat tccaatatca tacaagacaa cgggaaaagt ccgtgaattt gaagaataca
     6241 ttgaaaatga tgaagtaaat cagctttatt tcctagatat cgatattcat ggaattgaga
     6301 aaaagggatt tgaagtggct cagctcattc gtcattacaa tccttacgct attattgtct
     6361 ttatcactag tcgatcagag tttgcgactc taacctataa ataccaggta tcagccctag
     6421 attttgttga taaggatatc aatgatgaga tgtttaagaa gagaattgag caaaatatct
     6481 tctacacgaa gagtatgtta cttgaaaatg aagatgttgt agattatttc gactacaatt
     6541 acaagggaaa tgatttaaaa attccttacc atgatatttt gtatattgaa acaacagggg
     6601 tatctcataa attgcgcatt attggtaaga attttgcaaa agagttttat ggtaccatga
     6661 cagatattca ggaaaaggac aaacatactc agcgatttta ttctcctcac aagtcatttt
     6721 tggtaaatat aggcaatatc agagaaattg atcgaaaaaa cttagaaatt gttttctatg
     6781 aagaccatcg ttgtcctatt tcaagattaa aaattagaaa attaaaagat attttagaga
     6841 aaaaatctca aaagtgattg acaattagca agaaattgat ataatggtta tatctgctac
     6901 agatagaagg tccgttggtc aaggggttaa gacaccgcct tttcacggcg gtaacacggg
     6961 ttcgaatccc gtacggacta ttttatccgc catagctcag ttggtagtag cgcatgactg
     7021 ttaatcatga tgtcgtaggt tcgagtccta ctggcggagt atagataaaa gggaacacag
     7081 ctgtgttcct ctttttgtat caatttgtat caccaagcat tttcataagg aagtctgtta
     7141 tttcttgaga actttctttt tttccatgtg caatccaagt ttggcagaca ccaaaaagtg
     7201 catgagttag atagatgcta ctatattcta attcagtggt atttagattc agttgcataa
     7261 atcgcttttg taaatctata ctgagcatga tatgaagttt atttcgtaag aaattttgga
     7321 tttctttagt cccattttca gaaagaaggg cagccagaag tggttctgac tctagatatt
     7381 caaagacttc taaaatagcg tctcttttgt gatgagcatg tttttgaaaa atatattcaa
     7441 atgtatggaa tagcttgctt tgatagtgct caatcacatc atacttatcc ttatagtgag
     7501 tatagaagct ggaacgacta attccggctt tttctactaa tttgacagta gaaattttat
     7561 caaatggctg ttccatcagt aattgtacca tagcattttc aatagttcgc tttgttttta
     7621 agcgtttgtt actttcttgc atatttcctc cttgtaaaca aattagacta tatgtctaaa
     7681 aatagatttt ttatcttgta atttagattt tttaatgtat aatctattat attaaaattt
     7741 tagacaatat gtttaaaaaa ggagaaacta agtttaaaga atggaaagca atttaaaaaa
     7801 aaccaacctt tattattgtc atgatcggga tttctcttat tccagatctg tacaatatca
     7861 tatttttgtc atcaatgtgg gattcatatg ggcaattgtc tgacttacct gtggcagttg
     7921 taaataatga taaagaggct tcctataatg gtaatactat ggcaatagga aaagacatgg
     7981 tgtccaattt aaaagaaaat aaaaccttgg attttcattt tgtagatgaa gaggaaggaa
     8041 agaagggatt ggaagatggc gattactata tggtagtgac tttaccaagt gatttatctg
     8101 aaaaaacaac tacattatcc aatattcaat cgacagcagc ttatcaatca ttgacaagtg
     8161 agcaacaaac tgagataagt gattctgtat ctcaaaattc aactgatagt attcaatcgg
     8221 ctcagtcaat tgtagcttta gtacaagatt tacagggaag tttagaaaac ttacaaaatc
     8281 aatcttctaa tctttcgact ttaaaaaatc aatctaatca agtatcacct attacttcta
     8341 cttctttgat aggattgtca agtggattaa cagagataca aggagatgtt actagcaaat
     8401 tagttcctgc cagtcagtcg attgcatcag gtgtaaacgc atatactaca ggtgttgata
     8461 aagtttctca gggcgcaagt caactaagtg aaaaaaatgc caccttgaca ggtagtttgg
     8521 ataaactagt ttcaggctca aacaccttga cacaaaaatc ttctagattg acagcaggag
     8581 ttggttaatt acaatcagga tctgggcaat tagcagacaa atccagtcag ttactttcag
     8641 gtgcttctcc attagagaat agagctaata aattggcaga tggatctggg aaactagcag
     8701 aaggtggaac aaagttaact tctggattgg aagatttaca gacaggactt gcttctttag
     8761 gacaaggact aggtaatgct agtgatcaac tcaaatcagt atcaacagaa tctaaaaatg
     8821 cagagatttt gtcaaatcca ctcaatcttt caaaaacaga caatgatcaa gttcctgtaa
     8881 atggaatcgc aatagctcct tatatgatat cagttgctct ttttgttgca gcaatatcaa
     8941 caaatatgat atttgcgaaa ttgccttcag gacgtcatcc agagagccgt tgggcttggt
     9001 tgaaatcttg agctgaaata aatggtatta tagctgtttt ggcaggaatt ttggtatatg
     9061 gaggagttca gcttattggt ttaactgcta atcatgagat gagaatattt attctcatca
     9121 tcctaacaag tttagtattc atgtctatgg tgaccacttt agcaacgtgg aatagccgta
     9181 taggagcttt tttctcactt attttgcttt tactacagtt agcatcaagt gcaggtactt
     9241 atccacttgc tttgacaaat gatttcttta gatctattaa tccctggtta ccaatgagct
     9301 attcagtttc gggattacga caaacaatct ctatcaacaa gtcattttcc tagctgtcat
     9361 actagttcta tttactagtt taggtatgct agcctatcaa cataagaaaa tggaagaaga
     9421 ttaaaaaaat cgaccgatta actggtcgat tttttatgcc ttagatgact ttcgtctgtg
     9481 attatagatt ccaaatagta agagagaagt aaaggaacag attgctccag taataaaacc
     9541 attgggaatg aaggaaagtg taatagttcc tttccccttg ggaatgtcaa ctttcataaa
     9601 tccagtttga gcttgtttaa tttctatttt cttaccatct tggtaggcag accaaccttt
     9661 gtcataagga atggtgaaga aaatagatgt atcttgttgg acatcatatg tagcaaaaac
     9721 cttgttttta gaagttgata ctgtgacagg ttgttcttta attttttgaa ttgcctcggt
     9781 gaaagttttg gtatctaaac gatagaaggt aggagattca aatgatactt gtgaatttcc
     9841 agggaaacta acattgatat tgaaagtttt tttctcttta gtatatccta gattaaagaa
     9901 ggagaagaca ttatcagttg taaaagtctt tttttcacca tttacaagga tgtcaacctt
     9961 cttttgttta tcgttagaaa agtgaaggtt tatgaaagag agataaactt ggctgttttc
    10021 tggaacttca atttgatact ggattgctgc atcttcattt gaagaacttg tgacactaat
    10081 caaatcatta gtattttcta ttttttctgt tttttcataa ggtattggag aaaaataatc
    10141 aaaattgacg ttagcaagtt gatttaaaaa tgaggcctga ttatccaagg tatgttcatt
    10201 gaacttgaca tcattgtaaa cagattgact agcaactgca atcggaagag agtattgatt
    10261 ttcatatagg gtaagattat ctttttgata gatatcttta aagccatact tatcaatagg
    10321 actgtctgag atattgtact ggataccaaa taaactatca gccaaaatac tattatttgc
    10381 atatcggaga ttgagattag tcccagagga tttaaaacca agtttatcta aagtagagct
    10441 tgatgaacga tttcgaacag atgaaaattg agagattcca ttgtagttga atttcatact
    10501 gtcatttcct gtctgagttt gtagtttttc agtacgagta aattgatttc caatatatgt
    10561 tgagaaagat tccatagctg ggatatctcg actataagca cttcgagaag caaatcccca
    10621 ttccttagca attccgtcca tttgagatga agcatttaaa ctcatttcaa ccagtataaa
    10681 taaagagatt agaatggcaa atagattcac agatataaac tttttgataa ctgcaaggag
    10741 taaaagagaa tagacaacca aaaattcaag agtaagcaga atattcaaat ctgttaaaaa
    10801 agaataatgc gattttagat agatggtagc taaaaatcct gttactacaa gaaaaagcga
    10861 aactaaaaaa ttccagactt taagttcttt cagacgcttt aagacttctg ctgctgtgta
    10921 aattaacaag gtagagaaaa tccaagcata gcgatgtaaa aacatgtttg gagtatgcat
    10981 gccttgccaa aataagtcaa gagcttctat gtaaaagctt gcaattagaa atgcaaagaa
    11041 tattacatat atgagtttca cgtgaaactt aatagatttc agcgtaaaaa ataaaatggt
    11101 caaaataaag ggaaatagtc caacaaaaat cattgggatg gccccatact ttgttgtgtc
    11161 aaaggaacca atgaattgct tagcaaagag atcaagatac cagctacttt cagtttgaaa
    11221 ctttgtaact tcagtcaatt tttccccatg tgtctgtaaa tcaaatagag tgggaagagt
    11281 cataatcaaa ctagccatac cagctaaaaa ggagataact atgaaatcaa gaacagatga
    11341 ttttcgagtc ttaaagtccc acgaaatttg acagagatac cagaaaataa gaaacaatac
    11401 tgtcatatat ccaaaataat aattttgaat aaataagatt gacagacttg taaagtacaa
    11461 taggagtttc ttttcagtta tcagtagatg taaaccagtt ataattaaag gaatcaagat
    11521 aaaaacatct agccaggttt ttatctctaa ttgactgaca gtgaaactca tcagagcata
    11581 ggaagtagat aaggctagtt ttaaagtctg agggatagat tgaaacaatt tattcaaact
    11641 aaaaaaggtt gacagaccaa tcaatccaaa ttttaagaga gtggtcagat agacagcatc
    11701 tggcatattc gttagatcaa aaaagtaaac tagaggcgcg agaaaactac ccaagtaata
    11761 actagatagg gcatagaagt ttagccctag accacttgta aaggtgtaaa acagactact
    11821 atttccatgt aggatatttc gtaaggctac atcaaaaata acgtattgat gaaagccatc
    11881 tcctaataga ggagagttgt cgctattcca gtagatacct tgagatagat atactccaga
    11941 cataatcact acaggaatga tgaaagaaat aaaataggtt cgatatgttt ttaaaaatga
    12001 tttcatgtta cctcgtagaa tgatagaaaa ctcagttggt taacccaact gagttttgaa
    12061 gttttattta gtctttccaa agttctttaa cttttgcttg tacttctgca ttttctagga
    12121 attcatcgta ggtttcatcg atacggtcaa tgacgccatt tttagataag acaatgatat
    12181 ggttagccaa agtttgaata aactcgtggt catggctggc aaagatgatt gattctttaa
    12241 agtttttcaa tccatcattc aagcttgaga tagattccaa gtccaagtga tttgttggat
    12301 catcaagtac aaggacattt gattttaaga gcatgagttt tgaaagcatg acacgaactt
    12361 tttctccccc tgacaagaca tttacaggtt tgttaacttc atctccagag aagagcatac
    12421 ggccgaggaa accacgtagg aaagtattgt catcatcttc tttacttgcg aattgacgca
    12481 accagtcaag aattgattct cctcctgcaa aatcagctga gttatctttt ggtaggtaag
    12541 attgactagt tgtaactccc cacttgacag ttccttcata gtcaatatct cccatgattg
    12601 cacgaattaa tgcagtcgtt tgaatatcat tttgtccaat aagtgctgtc ttatcatctg
    12661 gacgcaagat gaaactaata ttatccaaga tagtttcacc atcaatcttt acagttagat
    12721 tttctactgt caagagatca ttaccaatct cacgttccgc tttaaagttg ataaatggat
    12781 atttacgact agatggtaca atctcttcta gctcaatctt atcaagcatt ttcttacgtg
    12841 atgttgcctg ccttgactta gaagcattgg cagagaaacg agcaacgaat tcttgcaatt
    12901 gtttaatttt ttcttctgct ttagcattac ggtctgctag caatttagca gcaagctcag
    12961 aagattcctt ccagaagtcg tagtttccga catagagttt gatttttcca aagtcaaggt
    13021 cggccatgtg agtacaaact ttgtttaaga agtgacggtc gtgggatact acgataactg
    13081 tgttatcaaa gtcaattaag aagtcttcta accaagtaat cgattggata tccaaaccgt
    13141 tagtaggctc gtccaagaga agaacatctg gtttaccaaa aagtgctttg gcgaggagaa
    13201 cctttacttt ttcaccgttg gccaattcgc tcatgttttg gtagtgtaat tcttctggaa
    13261 tgtttaggtt ttgaagtagt tgagaggctt cactctctgc ttcccaacct ccaagttcgg
    13321 caaactctcc ttcgagttcg gcagcacgaa ccccgtcctc gtctgagaaa tcttccttca
    13381 tgtagatagc atctttctct ttcatgatgc tataaagttt ttcatttccc atgataacga
    13441 catcaatggc acgttcatct tcgtagtcaa agtgattttg acgaagaaca gagagacgtt
    13501 catctggacc aagagagatg tgaccagtag taggttcgat atctccagct aaaattttta
    13561 aaaaggttga ttttccggca ccattagcac cgattaatcc gtaagtattt ccttctgtaa
    13621 atttgatatt gacatcatca aaaagtttgc gatcactaaa acgtagtgaa acatcagata
    13681 ctgtaagcaa tatttttctc ctatatgtgt aatatattta ttctactaga aaatacagaa
    13741 atattcaaat ttttattttt caattttgtg taaattatat ttacagtatc ctttacacaa
    13801 atctgtaaaa agcaaggctg atttattttg ataaattacg gttatttcat taaaaaaatg
    13861 ctataattga aaggactata tcgaaggaga acaaaatgac taaacccatt attttaacag
    13921 gagaccgtcc aacaggaaaa ttgcatattg gacattatgt tggaagtctc aaaaatcgag
    13981 tattattaca ggaagaggat aagtatgata tgtttgtgtt cttggctgac caacaagcct
    14041 tgacagatca tgccaaagat cctcaaacca ttgtagagtc tatcggaaat gtggctttgg
    14101 attatcttgc agttggattg gatccaaata agtcaactat ttttattcaa agccagattc
    14161 cagagttggc tgagttgtct atgtattata tgaatctagt ttcgttagca cgtttggagc
    14221 gaaatccaac agtcaagaca gagatttctc agaaaggatt tggagaaagc attccgacag
    14281 gattcttggt ctatccaatc gctcaagcag ctgatatcac agctttcaag gctaattatg
    14341 ttcctgttgg gacagatcag aaaccaatga ttgagcaaac tcgtgaaatt gttcgttctt
    14401 ttaacaatgc atataactgt gatgtcttgg tagagccgga aggtatttat ccagaaaatg
    14461 agagagcagg gcgtttgcct ggtttagatg gaaatgctaa aatgtctaaa tcactaaata
    14521 atggtattta tttagctgat gatgcggata ctttgcgtaa aaaagtaatg agtatgtata
    14581 cagatccaga tcatatccgc gttgaggatc caggtaagat tgagggaaat atggttttcc
    14641 attatctaga tgtttttggt cgtccagaag atgctcaaga aattgctgat atgaaagaac
    14701 gttatcaacg aggtggtctt ggtgatgtga agaccaagcg ttatctactt gaaatattag
    14761 aacgtgaact gggtcctatt cgtgagcgcc gtattgaatt tgctaaggat atgggagaag
    14821 tttataatat gattcaaaaa ggtagtgaaa gagcgcgtga agttgcgggt caaaccctat
    14881 ctgaggtaaa aggggcaatg ggacttcatt actttaacta agtttatttt acaagaaact
    14941 atcttttcta tctcgaagaa aagatagttt tttatttacc cctgtaacat ttgacaaatt
    15001 tttatagaat ggtatgatag atacaatata aaaagagtca agctcaaaaa gaaagaaaag
    15061 aggaaacttc gaatgtctaa ttgggacact aaatttttga aaaaaggttt tacctttgat
    15121 gatgtattgc ttattccagc tgaaagtcat gtgttgccta acgatgcaga tttaacaact
    15181 aaattggcag ataatttgac tttaaatatc ccaattatta ccgctgccat ggacacagtt
    15241 acagagagtc aaatggccat tgctattgct cgtgcaggcg gtctcggagt tatccataaa
    15301 aacatgtcaa ttgctcaaca agcagacgag gttcgtaagg taaaacgttc tgaaaatgga
    15361 gttattattg atccgttctt cttgacgcct gaacatacaa ttgctgaagc agatgagctt
    15421 atgggtcgtt accgcatcag tggtgttcca gttgttgaaa cacttgaaaa tcgtaaattg
    15481 gttggtattt tgacaaaccg agatcttcgt tttatttcag attataatca accaatttca
    15541 aaccatatga ctagtgaaaa tcttgttact gctcctgtgg gtacggatct tgcaacggct
    15601 gagagtattc ttcaagagca tcgtattgaa aaacttccgt tggtcgatga agaaggcagt
    15661 ctttctggtt tgatcactat caaagatatt gaaaaagtta ttgagtttcc aaatgcggct
    15721 aaagatgagt ttggtcgtct tctagttgca ggtgcagtag gtgttacttc agatacattt
    15781 gaacgtgcag aggctctttt tgaggcagga gcggatgcga ttgttattga tactgcacat
    15841 ggtcattctg caggtgtctt gcgtaaaatt gccgagattc gtgctcattt cccagatcgg
    15901 actttgattg ctggaaatat tgctactgct gaaggtgcac gtgcccttta tgaagcgggt
    15961 gtagacgttg ttaaggttgg tattggacca ggttctatct gtactactcg tgtgattgct
    16021 ggtgttggtg ttccgcaagt aacagctatc tacgatgctg cagctgttgc gcgcgaatat
    16081 ggtaaaacga ttattgctga cggtgggatc aagtattctg gagatattgt aaaagcactt
    16141 gctgcaggtg gaaatgctgt tatgcttgga tctatgtttg ctggaactga tgaagctcca
    16201 ggcgaaactg aaatcttcca aggacgtaaa ttcaagactt accgtggtat gggatcaatt
    16261 gctgctatga agaaaggttc aagcgaccgt tatttccaag gttctgtcaa tgaagcaaac
    16321 aagcttgttc cagaaggaat tgaaggtcgt gttgcttata aaggagcggc agctgatatt
    16381 gttttccaaa tgattggtgg tattcgctct ggtatgggtt actgtggtgc agctaacctt
    16441 aaagaactac acgataatgc tcaatttatt gaaatgtctg gtgctggttt gaaagaaagc
    16501 catcctcatg atgtgcaaat tactaatgag gcaccaaatt attctatgta aaaaacaatg
    16561 aaaagaactc cagtgaaaac aggagttctt ttacaatgtt gtcaatttcc atttacagaa
    16621 gctttaccat cctgaatagt gaagatactt agattttctg gcagattttg aagatggtct
    16681 aagcttgttg ttgtgataaa ggtttggatt gattgagaaa tcgtttctaa taattttaac
    16741 tgtctagtgt tgtcaagttc actcatcaca tcgtcaagca gtaatatcgg agattctgtg
    16801 gtaatgcttt ccattaattc gatttctgct aattttatcg agaggacgag actacgatgt
    16861 tgaccttggc ttccgaaact agcatccatc ccatttatat aaaaagaaat gtcatctcga
    16921 tgaggaccga caccagtatt ctttttaaat aaatctctgg atctactttt ttctaaagca
    16981 attttgaaag attcggataa gttttgtttg tcagttatat tgacagaaga ttgataggat
    17041 attgacaact cttcgatctg attagagagt tcaaaatgtt tcttacgccc aaatgattct
    17101 agttttttta tgaaatctaa gcggtgattc attacacgac atccataatc aactagctga
    17161 tcatctaaca cagaaaggaa tgtttcatct attttttgat ctgattttag gtaagtgttt
    17221 ctttgcttta ggatgtggtt ataattggtt aagtcagata agtagattgg cttaatttgc
    17281 ccaagttcca tatcaatgaa ttttcgtcga atcgaaggtg ctcctttaat tagttgtaaa
    17341 tcttcaggag caaataagac aacattcatg tgtcctacat aatctgaaag gcgtgcctgt
    17401 tttaagtgat taacttttgt tacacggcct ttttgtgtta gttcgatttc taggggaatg
    17461 gatccagttt ttttctgaac gagacctgaa agatgaagtt gttcctcatc aaaatgaatg
    17521 agatttttat ctgttcgagt tcgatgacta cgcgttaagg ctaaaaaata gatagcctct
    17581 aacatgtttg tttttccttg tgcattacgt cccaaaaaga cattcaattt aggattaaag
    17641 tctattttcg tttctttgta attacgaaaa gtcttgagag atagatgttg tagccacatg
    17701 attatctacc agggaatcgt ggagcttgtt ggcttttagg tgatgaagca ggtttcgatt
    17761 tgtctttttt aactccctta ttcatctttt tgacaagttt agcgatccgt tctttttcaa
    17821 ctttatcagc ttggtattca tcttgttctt cagaagtagg ttgtgtcaac aagatgtcaa
    17881 tgttcatgtc agggatgtca actttatcgc caatacgaag tttttttcca cgacgactct
    17941 ctaattccct attaaagtaa acagaatgtt cagagagaaa tgatttaata gctcctccgc
    18001 tatgtgtaat tccaagttct ttgagtagtg cttggagggt aataaattct tcaaataatt
    18061 tgtattccat aattcacctc aatctttggt attataccat attttcctaa aaatagtgag
    18121 agagacagcg agaaatgtaa gcgattttta tttcaaaagt gttacaggga acaagaaaat
    18181 ttcaggtttt cgtgatataa tagaagtctg tatataagga ggtaaatcat ggagttagtg
    18241 catggaattt caacacattt tatccaatca aaaaagttta aaacaaacaa aattaccgtg
    18301 cgttttaccg ctccattatc ccttgatacg attgcaggtc acatgttgag tgcaagtatg
    18361 ctagagactg ctaatcagat gtaccccact tctcaagatt tgaggagaca cttggccagt
    18421 ctatacggta cagatatgtc aaccaattgt ttcagaagag ggcaaagcca cattatagaa
    18481 ttgacattta cctatgttcg tgatgagttt ttaagtagga aaaacgtgct aacctctcag
    18541 attttggaac ttgtaaaaga aactcttttt tcacccgtag tagttgataa tgggtttgat
    18601 ccggccttat ttgaaattga gaaaaaacaa ttgctagcaa gtttagcagc tgatatggat
    18661 gattcttttt attttgcaca taaagaattg gataaattgt tttttcatga tgaacgtctt
    18721 caattggaat atagtgattt acgaaatcgt attttagctg aaactccaca aagttcttat
    18781 tcttgtttcc aagaattttt agccaatgat cgaatagatt tctttttcct aggtgatttt
    18841 aatgaggttg aaattcaaaa tgtattagaa tcatttggct ttaaaggtcg aaaaggagat
    18901 gtgaaggttc agtattgtca accttattct aatatccttc aggaaggtat ggttcggaaa
    18961 aatgtgggac aatccatttt ggaattaggt tatcattact gttctaaata tggtgatgag
    19021 caacatttac ccatgattgt aatgaatggt ttacttggtg gatttgctca ctctaagctc
    19081 tttacaaatg tccgtgaaaa tgctggatta gcttatacca tttcaagtga gcttgattta
    19141 tttagtggat tcttgaggat gtatgctggt atcaatcgag aaaatcgtaa ccaggctcgt
    19201 aaaatgatga ataatcaact gcttgattta aaaaaaggtt attttacaga gtttgagtta
    19261 aatcagacca aggaaatgat tcgttggtcg ttgttacttt ctcaagataa tcaatcttca
    19321 ttgattgaac gtgcttatca aaatgcctta tttggaaaat cttcagcaga ctttaaaagt
    19381 tggattgcaa agcttgaaca gattgacaaa gatgctattt gtagagtagc taataatgtg
    19441 aaactacaag cgatttactt tatggaagga atagaatgac aaaggttgtt tttgaagaaa
    19501 aatactatcc agctgtaaaa gaaaaggttt atcgaactcg tttggccaac ggattgacag
    19561 ttgctctttt gcctaaaaag gaatttaaag aggtttacgg gagtgtaact gtacagtttg
    19621 gttcgataga tacgcttgtc acagaagttg acggagatgt aaaacaatat cctggaggaa
    19681 ttgctcattt tcttgaacat aaattatttg agagagaaga ttctagtgat ttgatgtcgg
    19741 cttttacgag tctaggtgca gatagtaatg cctttacaag ctttacaaaa acaaactatc
    19801 ttttttcagc aacggattat tttttagaaa atttatattt acttgatgaa ttggtaacat
    19861 cagcacactt tactgaagct tccattctga cagagcagga tattattcag caagaacgag
    19921 aaatgtacca agatgatcca gattcgtgtt tattcttttc aactttagcg aatttgtatc
    19981 ctggtacacc tttagcaact gatatagttg gaagtgagga gtccatttcc caaatcaatc
    20041 taactaattt gcaagaaaat tttacaaagt tttacaaacc tgtaaacatg tctctgtttt
    20101 tagttggtaa ttttgatgtg gagcgagtac aggactattt tgaaagcaaa gaactgaaag
    20161 attcagattt tcaggaagta gcaagagaaa agttgttttt acagcctgta aagccaacag
    20221 atagtatgag aatggaagta tcttctccca aactagcgat tggagttaga ggtaagcgag
    20281 aagtttctga agcggattgc tatcgacatc atattttatt aaaattattg tttgcaatga
    20341 tgtttggttg gacttcggat cgttttcaaa aatgttatga atcaggtaaa attgatgcgt
    20401 ccttatctct ggaagttgaa ataacaagtc gctttcattt tgtcatgttg acaatggata
    20461 cgaaagagcc agttgctttg tctcatcaat ttaggaaggc tattcgtaat tttacaaagg
    20521 atttagatat tacagaggaa catttagata ttatcaaaag agagatgttt ggcgaatttt
    20581 tcagtagcat gaactctctt gaatttattg caacgcaata tgatgctttt gaaaatggtg
    20641 agacaatttt tgatttgccg aaaattttac aggaaattac tttagaggat gtccttgatg
    20701 ctggacatca tttaatagat gatggtgaca tagttgattt tacaatattc ccatcgtagt
    20761 aacctattat aatagacact agaaagaagg gatgacaagt atgagaaaaa aaacaattgg
    20821 agaggtttta cgattagcta gaatcaatca gggattgagt ttagatgaat tgcagaaaaa
    20881 gacagaaatc cagttagata tgttggaagc aatggaagca gacgatttcg atcaacttcc
    20941 aagtcctttt tacacgcgtt ctttcttgaa aaaatatgca tgggctgttg agttagatga
    21001 ccaaattgtt ttggatgctt atgattctgg gagtatgatt acttatgagg aagtagatgt
    21061 tgatgaagat gagttgacag gtcgtagacg ttcaagtaag aaaaagaaga aaaaaatatc
    21121 atttttacct ttattttatt ttatcttttt tgctttatcg attttaattt ttgtgactta
    21181 ttatgtttgg aactatattc aaactcaacc agaggagcct tctctttcta attacagtgt
    21241 ggttcaatca acaagttcaa ctagctctgt tccccactcc tcaagtagta gttcttctag
    21301 tatagaatca gctataagtg tatcaggcga aggaaatcat gtagaaatcg cttataagac
    21361 aagtaaggaa acagttaaat tgcaattggc agtttcagat gttacaagtt gggtcagtgt
    21421 ttcagaaagc gaacttgagg gcggtgtaac cttatcgcca aagaagaaaa gtgcagaagc
    21481 aacagttgca actaaaagtc ctgtaacaat tacgttaggt gttgtaaaag gtgttgattt
    21541 gacagtagat aatcagactg ttgatttatc gaaattaaca gctcagactg gacaaatcac
    21601 tgtaaccttt actaaaaatt aaggaaaaac gaatgaaaaa agaacaaatt cccaatctct
    21661 taacaatagg tcgaattctc tttataccta tttttatctt tattttaacg ataggaaatt
    21721 cgatagagag tcatatagtt gcagctatta tctttgctgt tgccagtatt accgactatt
    21781 tagatggata tttagctcgt aaatggaatg tggtcagtaa ttttggtaaa tttgcagatc
    21841 ctatggcgga taagttacta gttatgtcgg cttttattat gttgattgag ttaggtatgg
    21901 ctccggcttg gattgttgca gtgattatct gtcgtgagtt agctgtgaca ggtttaaggc
    21961 ttttattggt tgaaactggt ggaacaattt tagcagcagc aatgcctgga aaaattaaaa
    22021 cttttagtca gatgtttgcc attattttct tgctattaca ttggactttg cttggtcaag
    22081 ttctacttta tgtagcctta tttttcacta tctactctgg ctatgactat ttcaagggta
    22141 gtgcctatgt atttaaaggg acatttggtt cgaaatgaaa tcaataattg atgtaaaaaa
    22201 tctttctttt cgctataaag aaaatcagaa ctactacgat gtgaaggata ttacgtttca
    22261 cgtgaaacgt ggagaatggc tttcgattgt agggcataat ggtagtggta aatcaacgac
    22321 ggttcgatta attgatggct tactggaagc agaatccgga gagattgtaa ttgatggcca
    22381 acgtttgact gaggaaaatg tttggaatat acgtcgtcaa atcggtatgg tttttcaaaa
    22441 tccagacaat caatttgttg gagcgactgt tgaagatgat gttgcttttg gtttggaaaa
    22501 tcagggactt tctcgtcaag aaatgaaaaa gagagtggaa gaagctctgg ctttagttgg
    22561 catgttggac tttaaaaaga gagagccagc gcgtctatca ggtggccaaa agcaacgtgt
    22621 ggccattgca ggtgttgtag ccctaagacc agctatttta atcttagatg aagcaacgag
    22681 tatgttggat cctgaggggc gtagagaact tattgggaca gtaaaaggaa ttcgaaaaga
    22741 ctatgatatg acggtcattt ctattaccca tgatttggaa gaagtcgcca tgagtgatcg
    22801 cgtattggtc atgaaaaaag gggaaattga atcaactagt agtccaaggg agcttttctc
    22861 tcgaaatgat ttagatcaaa ttggattaga cgatcctttt gctaatcaat taaaaaaatc
    22921 tttgagccag aatggctatg atttacctga aaattatttg acagaaagtg agctagagga
    22981 taagctatgg gaattgctct agaaaatgtg aattttacat atcaagaagg tactccctta
    23041 gcttcagcag ctttgtcgga tgtttctttg acgattgaag atggctctta tacagcttta
    23101 attgggcaca caggtagtgg taaatcaact attttacaac tcttaaatgg tttattggtg
    23161 ccaagtcaag ggagtgtgag ggtttttgat accttaatca cctcgacttc taaaaataaa
    23221 gatattcgtc aaattagaaa acaggttggc ttggtatttc agtttgctga aaatcagatt
    23281 tttgaagaaa cggttttgaa ggacgttgct tttggaccgc aaaattttgg agtttctgaa
    23341 gaagatgctg tgaagactgc gcgtgagaaa ctggctctgg ttggaattga tgaatcactt
    23401 tttgatcgta gtccgtttga gctgtcaggg ggacaaatga gacgtgttgc cattgcaggc
    23461 atacttgcca tggagccagc tatattagtc ttagatgagc caacagctgg tctagatcct
    23521 ctagggagaa aagagttgat gaccctgttc aaaaaactcc accagtcagg gatgaccatc
    23581 gtcttggtaa cgcatttgat ggatgatgtt gctgaatatg cgaatcaagt ctatgtaatg
    23641 gaaaagggac gtttagtaaa ggggggcaaa ccaagtgatg tctttcaaga cgttgttttt
    23701 atggaagaag ttcagttggg agtacctaaa attacggcct tttgtaaacg attggctgat
    23761 agaggcgtgt catttaaacg attaccgatt aagatagagg agttcaagga gtcgctaaat
    23821 ggatagtatg attttagggc gttatatccc aggggattcg attgttcacc gattggatcc
    23881 acgtagcaaa ttgcttgcta tgatgctact gattttgatt gtgttttggg ctaataaccc
    23941 cttgacgaat ctgattcttt ttatagcgac agggatattt attgccttgt caggagtatc
    24001 tctttcattt tttattcagg gcttgaagtc tatgtttttc ttgattgcct tcacaactat
    24061 ttttcaacta tttttcattt ctaatgggaa tgttttattt gagttttcgt ttgtgagaat
    24121 cacggattat gctttgcaac aagctgggat tattttttgt cgctttgtat tgattatttt
    24181 cttttcaact ttgttaacct taacaaccat gcctttaagt ttggcatcag ctgtcgaagc
    24241 tttattagca cctttaaagc gtgtgaaagt tccagttcat gaaattggat tgatgctgtc
    24301 tatgagtttg cgttttgtcc caaccttgat ggatgatacg actcggatta tgaatgcaca
    24361 gaaagctcgt ggagtggatt ttggagaagg aagcatcgtt caaaaagtaa aggcgatgat
    24421 tcccattttg attcctcttt ttgcgacaag tttaaaacgt gcagattcct tggctatcgc
    24481 tatggaagcg cgtggctatc agggtggaaa aggcagaagt caataccgac aattgaaatg
    24541 gactctgaag gatacgctga ccattcttgt tattctcgta cttggttgtt gtttattttt
    24601 cttaaaatct tagtagcttt caggaattga taaaaagtta ctgtaacagt ttttgatata
    24661 aaggtaggaa tatgaaccgt tttaaaaaat caaaatatgt cattattgtt tttgtcactg
    24721 ttctgcttgt gtcagctctc ttagcgacga cttattcaag tacaattgtg acaaaattag
    24781 gagatggaat ctcattggtt gatagagttg tacaaaaacc ttttcagtgg tttgattctg
    24841 tcaaatcaga tttggctcat ttgacacgaa catataatga aaatgaaagt ttgaagaaac
    24901 agctttacca attagaagtt aaatcaaatg aggtggaaag tttaaagaca gaaaatgaac
    24961 aactgcgcca attgcttgat atgaagtcta aattgcaagc cacaaagact ttagcagcag
    25021 atgttattat gcgttctccg gtatcttgga agcaggagtt gaccttagat gcaggtagat
    25081 caaaaggtgc ttctgagaac atgttagcta ttgcaaatgg tggcttgatt gggagtgttt
    25141 caaaagtaga ggagaactct actatagtca accttctgac aaatacggaa aatgctgata
    25201 agatttctgt taaaattcaa catggctcta ctacaattta tggaattatt attggctatg
    25261 acaaggaaaa tgacgttctt aaaattagcc aattaaatag taatagcgat attagtgcgg
    25321 gagataaggt gactactggt ggattaggaa actttaacgt tgctgatatt cctgttggtg
    25381 aagtggttgc cacaacgcat agtacagact atttgacacg agaagtaact gttaaattga
    25441 gtgcagatac tcataatgta gatgtgatag aattagtggg gaattcataa tgagacagtt
    25501 gaagcgagtt ggagtatttt tattgcttcc tttctttgtt ctaattgacg cccatattag
    25561 ccagcttctg ggctcatttt tcccccatgt acatttggct agtcattttc tttttctatt
    25621 tctcttattt gagacgatag aagtatcaga gtatctctac ctagtctatt gttttgttat
    25681 aggcttggtt tatgatgttt actttttcca tctaataggg attacaactc tcttatttat
    25741 cttattggga gccttccttc ataaattgaa tagtgttatt ttgttgaatc gttggacaag
    25801 aatgctagct atgattgtgc tgacattcct gtttgaaatg ggtagttatc ttttggcttt
    25861 tatggtaggg ttgacagtag atagcatgtc gatttttata gtctatagct tggtaccgac
    25921 gatgatttta aattttttat ggattactgt ttttcaattt atttttgaaa aatattatct
    25981 ataagaacga catataaatg taacaaaggc gtaatattta ttaggccttt ttttggtata
    26041 ctagtattgt ctttaaaaga aggagtatct acgtaatatg aagaaaaaaa tcttagcgtc
    26101 acttttatta agtacagtaa tggtttctca agtagctgtt ttaacaactg cgcatgcaga
    26161 aacgactgat gacaaaattg ctgctcaaga taataaaatt agtaacttaa cagcacaaca
    26221 acaagaagcc caaaaacaag ttgaccaaat tcaggagcaa gtatcagcta ttcaagctga
    26281 gcagtctaac ttgcaagctg aaaatgatag attacaagca gaatctaaga aactcgaggg
    26341 tgagattaca gaactttcta aaaacattgt ttctcgtaac caatcgttgg aaaaacaagc
    26401 tcgtagtgct caaacaaatg gagccgtaac tagctatatc aataccattg taaactcaaa
    26461 atcaattaca gaagctattt cacgtgttgc tgcaatgagt gaaatcgtat ctgcaaacaa
    26521 caaaatgtta gaacaacaaa aggcagataa aaaagctatt tctgaaaaac aagtagcaaa
    26581 taatgatgct atcaatactg taattgctaa tcaacaaaaa ttggctgatg atgctcaagc
    26641 attgactacg aaacaggcag aactaaaagc tgctgaatta agtcttgctg ctgagaaagc
    26701 gacagctgaa ggggaaaaag caagtctatt agagcaaaaa gcagcagctg aggcagaggc
    26761 tcgtgcagct gcggtagcag aagcagctta taaagaaaaa cgagctagcc aacaacaatc
    26821 agtacttgct tcagcaaaca ctaacttaac agctcaagtg caagcagtat ctgaatctgc
    26881 agcagcacct gtccgtgcaa aagttcgtcc aacatacagt acaaacgctt caagttatcc
    26941 aattggagaa tgtacatggg gagtaaaaac attggcacct tgggctggag actactgggg
    27001 taatggagca cagtgggcta caagtgcagc agcagcaggt ttccgtacag gttcaacacc
    27061 tcaagttgga gcaattgcat gttggaatga tggtggatat ggtcacgtag cggttgttac
    27121 agctgttgaa tcaacaacac gtatccaagt atcagaatca aattatgcag gtaatcgtac
    27181 aattggaaat caccgtggat ggttcaatcc aacaacaact tctgaaggtt ttgttacata
    27241 tatttatgca gattaattta cagagggact cgaatagagc cctcttttca ggttttaccg
    27301 tgacaatccc tattaaaaat tatatcaaaa tagcttgaaa atattggaaa agtatggtag
    27361 aatgaaaatt gtcgtgtgaa cgataatact cattcttgat gaattgtgaa gcagttgccc
    27421 ttgggtcgtt ttgcgagttg aagtcaagaa gaggaaaaaa acaaaaagga gaaatactca
    27481 tggcagtaat ttcaatgaaa caacttcttg aggctggtgt acactttggt caccaaactc
    27541 gtcgctggaa tcctaagatg gctaagtaca tctttactga acgtaacgga atccacgtta
    27601 tcgacttgca acaaactgta aaatacgctg accaagcata cgacttcatg cgtgatgcag
    27661 cagctaacga tgcagttgta ttgttcgttg gtactaagaa acaagcagct gatgcagttg
    27721 ctgaagaagc agtacgttca ggtcaatact tcatcaacca ccgttggttg ggtggaactc
    27781 ttacaaactg gggaacaatc caaaaacgta tcgctcgttt gaaagaaatt aaacgtatgg
    27841 aagaagatgg aactttcgaa gttcttccta agaaagaagt tgcacttctt aacaaacaac
    27901 gtgcgcgtct tgaaaaattc ttgggcggta tcgaagatat gcctcgtatc ccagatgtga
    27961 tgtacgtagt tgacccacat aaagagcaaa tcgctgttaa agaagctaaa aaattgggaa
    28021 tcccagttgt agcgatggtt gacaccaata ctgatccaga tgatatcgat gtaatcatcc
    28081 cagctaacga tgacgctatc cgtgctgtta aattgatcac agctaaattg gctgacgcta
    28141 ttatcgaagg acgtcaaggt gaggatgcag tagcagttga agcagaattt gcagcttcag
    28201 aaactcaagc agattcaatt gaagaaatcg ttgaagttgt agaaggcgac aacgcttaat
    28261 ttatacaaat agtaattacc taggagggcg gggcttagcc cggctctcct attttcaaaa
    28321 aatataggag aattaaaatg gcagaaatta cagctaaact tgtaaaagag ttgcgtgaaa
    28381 aatctggtgc cggtgttatg gacgctaaaa aagcgcttgt agaaacagac ggtgacatcg
    28441 aaaaagcgat tgaattgctt cgtgaaaaag gtatggctaa ggcagctaag aaagctgacc
    28501 gtgttgctgc agaaggtttg actggtgttt atgttaacgg taatgttgca gcagttattg
    28561 aagtaaacgc tgaaactgac ttcgttgcaa aaaacgctca attcgttgaa ttggtaaata
    28621 ctacagctaa agtcattgct gaaggaaaac ctgctaacaa cgaagaagct cttgctttga
    28681 taatgccttc aggtgaaact cttgaagctg catacgtatc tgcaacagca actatcggag
    28741 agaaaatctc attccgtcgc tttgcattga ttgaaaaaac agacgcacaa cactttggag
    28801 cataccaaca taacggtgga cgtatcggtg ttatttcagt tgttgaaggt ggagacgaag
    28861 cacttgctaa acaattgtca atgcacatcg cagcgatgaa accaacagtt ctttcttaca
    28921 aagaattgga tgagcaattc gttaaagatg agttggcaca attgaatcac gttatcgacc
    28981 aagacaacga aagccgtgca atggttaata aaccagctct tccacacttg aagtatggat
    29041 caaaagctca attaactgat gatgttattg ctcaagctga agctgacatc aaagctgaat
    29101 tggctgcaga aggtaaacca gaaaaaatct gggacaaaat tattccaggt aaaatggatc
    29161 gcttcatgct tgataacact aaagttgacc aagcttacac acttcttgca caagtttaca
    29221 tcatggatga cagcaagaca gttgaagcat accttgaatc agttaacgct tcggtagttg
    29281 agtttgctcg ctttgaagtt ggtgaaggta tcgagaaagc tgcaaacgac ttcgaagctg
    29341 aagttgcagc tacaatggca gcagccttga ataactaata atagaaagga agcaaattgc
    29401 ttcctttttt gtatagggct tagatttttc ctgaaattgt tttttcccca gcctcactcg
    29461 attagaataa ttaaaacaaa aagccctata ataagggcta agtgcattta ggagactata
    29521 cttcaaattc atagtaagcg cgtcataaca aggtatctat cctaattccc caacttccag
    29581 tatactagat aaaaaataat tatcggagga aaggtattgt actatgataa ttcaactaag
    29641 tgatttaggt caagttcacc ttgtttgtga caagacagat atgaggtagg gaatagactc
    29701 attagcctat gtagttaaaa cccactttga attggattct ttctccggtc aagtctttct
    29761 cttttgtggt gaacgtaaag accgctttaa agccctttac tgggatggtc aaggattttg
    29821 gctactatat aaacgctttg agaacggaaa actgacttgg ctaagtacag aaaaggatgt
    29881 caaagctctc gcacctgaac aagtagattg gcttatgaag ggcttttcta tcactccaaa
    29941 aatatagtag attgaaacta gaatagtaca cctctgcttc taaaacattg ttagaaatcg
    30001 atttgattgt cctgatcgat ttgtcctgtt cttatttcat tttactataa atccatcaga
    30061 aagttgtgat ttctattgaa atgaggactt tctttttaca ctcatctgct ttcaaaaagc
    30121 attctagtcc atctccgatt aacgatggac tttatcacct ccttctccag tccttgtatg
    30181 acatcttcca aagttcgaaa ggctttattc ttaaatccac gtttacgaat ctctttccat
    30241 acttgttcaa tggggttcat ctctggtgtg tatggaggaa taaatgcaaa gccaatatta
    30301 gtcggaatct ttaaggtact tgatttatgc catatagcat tgtccataac gagtaaaaga
    30361 taatcatctg gataagcttg tgaaagctcc tattcctaaa gcccctttag cgcatagctt
    30421 tggctcagct tctattatcg ctcacaccat ccatcagaag tttaatctga aggtacccaa
    30481 ttatcgccaa gaagaagatt gggctaagat gggtttacca atcacacgca aggaaatctc
    30541 taattggcat atcaagacga gtcaatacta tttggagccc ctctataacc tcttgcgaga
    30601 gagactattg actcagccct tacttcatgc ggatgaaact tcttataggg tgctagagag
    30661 tgatagtcag ctgacttact attggacttt tttgtctggg aaagctgaga aacaagggat
    30721 tacgctttac catcatgtcc taatcgattt gttcatatct tatttcaatc cattataaat
    30781 agtgagaaat atctatccta tcttctagaa tgtcttccaa acgtggaaac tctcgtaaac
    30841 aaagaggttt tagaggctta tttaccatgg actaaaattg tacaagaaaa gtgcaaataa
    30901 gaaatctcca gattaggaac tatccgtgag ttctctagtc tggagatttt tcaatatact
    30961 tcgttattgg acggttacaa ttcataaagt gctgtagaga gataacgttc accgttatct
    31021 ggtgctaggg caaggacttt tttacctgta cctaattttt tggcaacctc gatggctccg
    31081 tagatagctg cagctgagga aatccctaca aggaagcctt cttttccacc aatttcacgt
    31141 ccgagtgcaa gagcgtcatc tgatgttaca cgaacgatac cattataggc tttagtatca
    31201 agtgtatcag gaataaatcc agctgagata ccttgaattt tgtgaggacc aggtttttca
    31261 ccagatagaa tagcagattc atctgcttct actgcaaaaa cttgaatgtt agaattttct
    31321 gatttgagtg catgagaaac accagaaatc gttccaccgg tacctactcc agcaacaaag
    31381 gcatctaatc catctttacc gaaagcagct agtatctcag ctcctgttgt tctttcgtgt
    31441 acttctggat tagctggatt gtcaaattga agaggaagga aaccatcacg ttcagcagcg
    31501 atttcttgag ccttagcaat agcacctttc attccctcgc taccaggagt taggacgagt
    31561 tcagcaccat aagcttggat aattttacgt cgttctacac tcatagtttc aggcataacg
    31621 atgacgactt tatacccttt agcagcacct acccatgaaa gtccaatacc agtgtttcca
    31681 cttgttgctt caacaatagt agaaccaggt ttcagaatac catcttgttc agctttttca
    31741 atcatgctaa gggcaatacg gtcttttaca gatgaaccag gattaaatgc ttcaagcttt
    31801 atatagacgt ctgcagcacc ttctggcacg atgttgttaa gtttaacaat cggtgtttga
    31861 ccgattaatt cagtaatgtt gttataaata gacatatgaa tacctctttg tataagatat
    31921 ctttagtata acgctatcca taccatttgt aaaatataga aatcctatcg aagcgatagg
    31981 atttctatat atcatagatc aaagtcatta attttcaagt gattgcgttc agctaattct
    32041 agtaaatagg tgtgaaggaa aacgctatca ggtttcgttt gaattgcttc attttctagt
    32101 atattttggt acgcatcttt ttattttgct cgctaaagta gttgtgagaa tgtcaacgaa
    32161 acgctgtatt attcattgtt tacactaagt ttacaggaac ttcaacctct cgtaaacctt
    32221 ggtcagttaa agtgactttt ccattaaaaa actccacaag tgcagcttta atagtttctt
    32281 tttcttcttt atcaacataa atcatcgtat cgacttgatc tgtaaagttt gtatccagct
    32341 ccatgagatc atgttcttta aggaagttac tgtactcttg gtactgagca taagacattt
    32401 gaatagcaat gccagcctgt tcttttattt caataatacc aatttctttg acagctaagg
    32461 cgacactgcc ggcgtaagca cgaattagtc ctccagcgcc tagtttaata ccaccaaagt
    32521 agcgtgtcac gaccacacag acattggtga gattgtgatt ttctagtacc ccaagcatgg
    32581 gaacaccagc agtaccacta ggctcaccat tatcacttgt acgtttaatt tcactacgtt
    32641 ctccaataat aaaggcagag cagttatgtg tcgctttgta gtgttctttt ttgatggcag
    32701 taatgaagtc acgagcctct tcttcgctat aaacacgctt ggcatggcag ataaagcgag
    32761 atttttttat ttcttcttgg acttggccgt cctctttaat tgtcctaaat tccatgattt
    32821 aattgtacta aaaaataatc taaagtgcta gtttttacga atagagaagt atgaaagtaa
    32881 atttagatta tctcggtcgt ttatttactg agaatgaatt aacagaagaa gaacgtcagt
    32941 tggcggagaa acttccagca atgagaaagg agaaggggaa acttttctgt caacgttgta
    33001 atagtactat tctagaagaa tggtatttgc ccatcggtgc ttactattgt cgagagtgct
    33061 tgctgatgaa gcgagtcaga agtgatcaaa ctttatacta ttttccgcag gaggattttc
    33121 cgaagcaaga tgttctcaaa tggcgcggcc aattaactcc ttttcaagag aaggtgtcag
    33181 agggactgct tcaagcagta gacaagcaaa agccaacctt agttcatgcg gtaacaggag
    33241 ctggaaagac agaaatgatt tatcaagtag tggctaaagt gatcaatgcg ggtggtgcag
    33301 tgtgtttggc tagtcctcgc atagatgttt gtttggagct gtacaagcgc ctgcaacagg
    33361 atttttcttg cgggatagct ttgctacatg gagaatcgga accttatttt cgaacaccac
    33421 tagttgttgc aacaacccat cagttattga agttttatca agcttttgat ttgctgatag
    33481 tggatgaagt agatgctttt ccttatgttg ataatcccac gctttaccac gctgtcaaga
    33541 atagtgtaaa ggagaatgga ttgagaatct ttttaacagc gacttcgacc aatgagttag
    33601 ataaaaaggt ccgtttagga gaactaaaaa gactgagttt accgagacgg tttcatggaa
    33661 atccgttgat tattccaaaa ccaatttggt tatcggattt taatcgctac ttagacaaga
    33721 atcgtttgtc accaaagtta aagtcctata ttgagaagca gagaaagaca gcttatccgt
    33781 tactcatttt tgcttcagaa attaagaaag gggagcagtt agaagaaatc ttacaggagc
    33841 aatttccaaa tgagaaaatt ggctttgtat cttctgtaac agaggatcga ttagagcaag
    33901 tacaagcttt tcgagatgga gaactgacaa tacttatcag tacgacaatc ttggagcgtg
    33961 gagttacctt cccttgtgtg gatgttttcg tagtagaggc caatcatcgt ttgtttacca
    34021 agtctaattt gattcagatt ggtggacgag ttggacgaag catggataga ccgacaggag
    34081 atttgctttt cttccatgat gggttaaatg cttcaatcaa gaaggcgatt aaggaaattc
    34141 agatgatgaa taaggaggct ggtctatgaa gtgcttgtta tgtgggcaga ctatgaagac
    34201 tgttttaact tttagtagtc tcttacttct gaggaatgat gactcttgtc tttgttcaga
    34261 ctgtgattct acttttgaaa gaattgggga agagaactgt ccaaattgta tgaaaacaga
    34321 gttgtcaaca aagtgtcaag attgtcaact ttggtgtaaa gaaggagttg aagtcagtca
    34381 tagagcgatt tttacttaca atcaagctat gaaggatttt ttcagtcggt ataagtttga
    34441 tggagacttc ctgttaagaa aagttttcgc ttcattttta agtgaggagt tgaaaaagta
    34501 caaagagtat caatttgttg taattcccct aagtcctgat agatatgcta atagaggatt
    34561 taatcaggtt gagggcttgg tagaggcagc aggctttgag tatctggatt tattagagaa
    34621 aagagaagag ggagccagtt cttctaaaaa tcgttcagag cgcttgggga cagaacttcc
    34681 tttctttatt aaaagtggag tcactattcc taaaaaaatc ctacttatag atgatatcta
    34741 tactacagga gcaactataa atcgtgttaa gaaactgttg gaagaagctg gtgctaagga
    34801 tgtaaaaaca ttttcccttg taagatgagg aaaaaatttg caaaaataga atgaaagcgt
    34861 tataataaaa tcataaaaac aaaaatgttt agaaagaagg tactcatatg attaaatata
    34921 gtatccgtgg tgaaaaccta gaagtaacag aagcaattcg tgattatgta gtttctaaac
    34981 tcgaaaagat cgaaaagtac ttccaaccag aacaagagtt ggatgcccga attaacttaa
    35041 aagtttatcg tgaaaaaacg gctaaagtgg aagtaacgat tccgcttgga tctattactc
    35101 tccgcgcaga agatgtatct caagatatgt atggttcaat tgaccttgta actgataaaa
    35161 ttgaacgtca gattcgtaaa aataaaacaa aaatcgagcg taaaaataaa aataaggtag
    35221 caactggtca attatttaca gatgctttgg tggaagattc aaatgttgtc cagtctaaag
    35281 ttgttcgttc aaaacaaatt gatttaaaac caatggattt ggaagaagca attctacaaa
    35341 tggatttatt ggggcatgat ttctttatct atgtggatgt tgaagatcaa acaaccaatg
    35401 tgatttatcg tcgtgaggat ggcgaaattg gtttgttaga ggttaaagaa tcttaatttc
    35461 aatatgtgta aaggtaggtt tactgaattg taaactacct ttttcttata attgatagaa
    35521 ttactgatta cacttttaaa aagtcgcttt ttgaggggta ttatggtata atgggtgcca
    35581 agaggttttg aatgaaaaaa ttttatgtaa gtccaatttt tcctattcta gtaggattga
    35641 ttgcgtttgg agtcttatcc actttcatta tttttgttaa taataatctg ttgacggttt
    35701 taattttgtt tctttttgta ggaggctatg tttttttatt taagaaactg agagtgcatt
    35761 atacaaggag tgatgtagaa cagatacagt atgtaaacca ccaagcggaa gaaagtttga
    35821 cagctctatt ggaacagatg cctgtaggtg ttatgaaatt gaatttatct tctggagagg
    35881 ttgagtggtt taatccctat gctgaattga ttttgaccaa ggaagatggt gattttgatt
    35941 tagaagctgt tcaaacgatt atcaaggctt cagtaggaaa tccgtctact tatgccaagc
    36001 ttggtgagaa gcgttatgct gttcatatgg atgcttcttc cggtgttttg tattttgtag
    36061 atgtatccag ggaacaagcc ataacagatg aattggtaac aagtcgacca gtgattggga
    36121 ttgtctctgt ggataattat gatgatttgg aggatgcaac ttctgagtca gatattagtc
    36181 aaatcaatag ttttgtagct aattttatat cagagttttc agaaaaatac atgatgtttt
    36241 ctcgtcgggt aagtatggat cgattttatc tatttactga ctacacggtg cttgagggct
    36301 tgatgaatga taaattttct gttattgatg ctttcagaga agagtcgaaa cagagacagt
    36361 tgcccttgac cttaagtatg ggattttctt atggcgatgg aaatcatgat gagataggga
    36421 aagttgcttt gctcaatttg aacttggctg aagtacgtgg tggcgaccag gtggttgtta
    36481 aggaaaacga cgaaacgaaa aatccagttt attttggtgg tgggtctgct gcttcaatca
    36541 agcgtacacg gactcgtacg cgcgctatga tgacagctat ttcagataag attcggagtg
    36601 tagatcaggt ttttgtagtc ggtcacaaaa atttagacat ggatgctttg ggctctgctg
    36661 taggtatgca gttgttcgcc agcaatgtga ttgaaaatag ctatgctctt tatgatgaag
    36721 aacaaatgtc tccagatatt gaacgagctg tttcattcat agaaaaagaa ggagttacga
    36781 agttgttgtc tgttaaggat gcaatgggga tggtgaccaa tcgttctttg ttgattcttg
    36841 tagaccattc aaagacagcc ttaacattat caaaagaatt ttatgattta tttacccaaa
    36901 ccattgttat tgaccaccat agaagggatc aggattttcc agataatgcg gtcattactt
    36961 atatcgaaag tggtgcaagt agtgccagtg agttggtaac ggaattgatt cagttccaga
    37021 attctaagaa aaatcgtttg agtcgtatgc aagcaagtgt tttgatggct ggtatgatgt
    37081 tggatactaa aaatttcacc tcgcgagtaa ctagtcggac atttgatgtt gctagctatc
    37141 tcagaacgcg cggaagtgat agtattgcta tccaggaaat cgctgcgaca gattttgaag
    37201 aatatcgtga ggtcaatgaa cttattttac aggggcgtaa attaggttca gatgtactaa
    37261 tagcagaggc taaggacacg aaatgctatg atacagttgt tattagtaag gcagcagatg
    37321 ccatgttagc catgtcaggt attgaagcga gttttgttct tgcgaagaat acacaaggat
    37381 ttatctctat ctcagctcga agtcgtagta aactgaatgt acaacggatt atggaagagt
    37441 taggcggtgg aggccacttt aatttggcag cagctcaaat taaagatgta accttgtcag
    37501 aagcaggtga aaaactgaca gaaattgtat taaatgaaat aaaggaaaag gagaaagaag
    37561 aatgaaagta atctttttag cagatgttaa aggaaaaggt aaaaaaggcg aaattaagga
    37621 agtaccaaca gggtatgcgc aaaactttct tatcaaaaag aatctagcca aagaagcgac
    37681 tgctcaagct gtaggtgaac ttcgtggtaa acaaaaatcg gaagaaaaag ctcacgctga
    37741 gatgattgca gaaggaaaag caattaaagc acaacttgaa gcagaagaaa ctgttgtaga
    37801 atttgttgaa aaagttggtc cagatggtcg tacctttggt tctattacca ataagaagat
    37861 tgcagaagaa ttgcaaaagc aatttggaat taagattgat aaacgtcata ttcaagtaca
    37921 agctccgatt cgagcggttg gtttgattga tgtgccagtg aaaatctatc aagatatcac
    37981 aagtgtaatc aatcttcgtg tgaaagaagg ataagtttac accttcttga caagattgta
    38041 aaaggaaggg aagtctgatg gcagaagtag aagagttacg agtacaacct caagatatct
    38101 tagctgagca atccgtttta ggggctatct ttattgatga gagtaaactt gtttttgtgc
    38161 gagaatacat tgagtctcgg gactttttta agtatgccca tcgtttgatt ttccaagcca
    38221 tggtcgattt atccgatcgt ggtgatgcca tagatgcaac aacggttcgt actatccttg
    38281 ataatcaagg tgatttacag aatattggtg gcttgtctta cttggttgag attgttaatt
    38341 ctgtgccaac ttctgctaat gcggagtatt atgctaagat tgttgcagaa aaagcaatgc
    38401 tacgtcgttt aattgccaag ttgacagagt ctgtcaacca agcttacgaa gcgtcacaac
    38461 cagctgatga aattattgct caggcagaaa aagggctgat tgatgtcagt gaaaatgcaa
    38521 atcgaagcgg gtttaagaac attcgagatg tgttgaatct caactttgga aatctggaag
    38581 ctcgctcgca acaaacgacc gatattacag gtattgcgac aggttatcgt gatttggatc
    38641 atatgacaac aggacttcat gaggaggagt tgattatctt agcagctcgt ccagcagttg
    38701 gtaagacagc atttgccttg aatatcgctc agaacattgg gactaagttg gacaaaacgg
    38761 ttgctatttt ttcactcgaa atgggtgcgg aaagcttggt agatcgtatg ttagctgcag
    38821 aaggcttggt ggagtcacat tctatccgta cagggcaatt gacagatgag gagtggcaaa
    38881 aatatactat tgctcagggt aatctagcta acgccagtat ctatatcgat gatacgccag
    38941 gtattcggat tacagagatt cgttctcgtt ctcgtaaatt ggctcaagaa actggaaatc
    39001 ttggtttgat tttgatagac tatttacaac ttatcacggg aactggtcga gaaaatcgtc
    39061 aacaagaagt ttctgaaatt tctcgtcagt tgaaaatact agccaaggaa ttgaaggttc
    39121 cagtaatcgc tctgagtcag ctttctcgtg gtgtagaaca acgtcaggac aagagaccgg
    39181 tcttgtctga tattcgtgaa tctgggtcta ttgagcagga cgctgatatc gtagcttttc
    39241 tctatcgcga tgactactat gaacgtggtg gtgaagaaga ggagggtatc ccaaataata
    39301 aggtggaagt tattatcgag aaaaaccgta gtggagctcg tggaacagtg gaattgattt
    39361 tccaaaaaga atacaataaa ttttcaagta tctcaaagag ggaggcataa gatgtcagat
    39421 gcatttacag atgtagccaa gatgaaaaaa atcaaagaag aaatcaaggc acatgaggga
    39481 caagtcgtag aaatgacttt ggagaatggt cgtaagcgcc aaaaaaatag attgggtaag
    39541 ctaattgaag tttatccatc cctatttatt gtggagtttg gggatgtgga aggagataaa
    39601 caagttaatg tttacgttga atcctttact tactcagata ttcttacaga aaagaatttg
    39661 attcattatc ttgactaaag tgagaaattt tctcactttt tcttttttct ccgaataatt
    39721 taggtgaagg caatcatcgc tttatattat ttttcaagga ggaagaatga aaattttacc
    39781 gtttatagca agaggaacaa gttattactt gaagatgtca gttaaaaagc ttgttccttt
    39841 tttagtagta ggattgatgc tagcagctgg tgatagtgtc tatgcctatt ccggaggaaa
    39901 tggatcgatt gcgcgtgggg atgattatcc tgcttattat aaaaatggga gccaggagat
    39961 tgatcagtgg cgcatgtatt ctcgtcagtg tacttctttt gtagcctttc gtttgagtaa
    40021 tgtcaatggt tttgaaattc cggcagctta tggaaatgcg aatgaatggg gacatcgtgc
    40081 tcgtcgggaa ggttatcgtg tagataatac accgacgatt ggttccatta cttggtctac
    40141 tgcaggaact tatggtcatg ttgcctgggt gtcaaatgta atgggagatc agattgagat
    40201 tgaggaatat aactatggtt atacagaatc ctataataaa cgaattataa aagcaaacac
    40261 gatgacagga tttattcatt ttaaagattt ggatggtggc agtgttggga atagtcaatc
    40321 ctcaacttca acaggcggaa ctcattattt taagaccaag tctgctatta aaactgaacc
    40381 cctagttagt gcaactgtga ttgattacta ttatcctgga gagaaggttc attatgatca
    40441 aattctcgaa aaagacggct acaagtggtt gagttatacg gcttataacg gaagtcgtcg
    40501 ctatatacag ctagagggag tgacttcttc acaaaattat cagaatcaat caggaaatat
    40561 ctctagctat ggatccaata atagttcaac tgtcggttgg aagaaaataa atggtagttg
    40621 gtatcatttc aaatcaaatg gttctaaatc aacaggatgg ctgaaagacg gttctagctg
    40681 gtattatttg aaattatctg gtgaaatgca gacaggatgg ttaaaggaaa atggtttgtg
    40741 gtattatctg ggtagttcag gggcaatgaa aacaggctgg taccaggtct ctggtaagtg
    40801 gtattattct tactcttcag gcgccttagc tgttaatacg acggtggatg gctacagagt
    40861 aaacagtgat ggagaacgag tatagaaaat tggagtagga gaaatttcct gctcttttct
    40921 gtaagcagtt tccttgacat ttttcttatt ttgcgctatc atatatacat ataatatatg
    40981 ggagtctgtg tacagtctga gaggaagtgt taaacttcga ccgcacctga tctgggtaat
    41041 gccagcggag ggaacgatac ttagtctaat tttgcacctt ttccatgtat ggtaaaggtt
    41101 tttctttttt ttaaaaggaa aacgagaaga ggaggttctt atgaaagcaa gcattgcctt
    41161 gcaagtttta cccctagcac aggggattga tcggatagct gttattgatc aggtcattgc
    41221 ttatctgcaa actcaagaag tgacgatggt agtgacacca tttgaaacgg tcttggaagg
    41281 ggagtttgat gagcttatgc gcattctaaa agaagcgctg gaagtggcag ggcaggaggc
    41341 agacaatgtc tttgccaatg tcaaaataaa tgtaggagag attttaagta ttgatgagaa
    41401 acttgaaaag tatactgaga cgacacatta gtctattggg ctttctcgga gtattgtcaa
    41461 tctggcagtt agcaggtttt cttaaacttc tccccaagtt tatcctgccg acacctcttg
    41521 aaattctcca gccctttgtt cgtgacagag aatttctctg gcaccatagc tgggcgacct
    41581 tgagagtggc tttactgggg ctgattttgg gagttttgat tgcctgtctt atggctgtgc
    41641 tcatggatag tttgacttgg ctcaatgacc tgatttaccc tatgatggtg gtcattcaga
    41701 ccattccgac cattgccata gctcctatcc tggttttgtg gctgggttat gggattttgc
    41761 ccaagattgt cttgattatc ttaacaacaa cctttcccat catcgttagt attttggacg
    41821 gttttaggca ttgcgacaag gatatgctga ctttgtttag tctgatgcga gcaaaccctt
    41881 ggcaaatcct gtggcatttt aaaatcccgg ttagcctgcc ttacttttat gcaggtctga
    41941 gggtcagtgt ctcctacgcc tttatcacaa ctgtggtatc tgagtggttg ggaggttttg
    42001 aaggtcttgg tgtttatatg attcagtcta aaaaactgtt tcagtatgat accatgtttg
    42061 ccattattat tctggtgtcg attatcagtc ttttgggtat gaagctggtc gatatcagtg
    42121 aaaaatatgt gattaaatgg aaacgtactt aaaatagagc gtttttgaaa aagaaaagag
    42181 gaaatcaaaa tgaagaaaac atggaaagtg tttttaacgc ttgtaacagc tcttgtagct
    42241 gttgtgcttg tggcctgtgg tcaaggaact gcttctaaag acaacaaaga ggcagaactt
    42301 aagaaggttg actttatcct agactggaca ccaaatacca accacacagg gctttatgtt
    42361 gccaaggaaa aaggttattt caaagaagct ggagtggatg ttgatttgaa attgccacca
    42421 gaagaaagtt cttctgactt ggttatcaac ggaaaggcac catttgcagt gtatttccaa
    42481 gactacatgg ctaagaaatt ggaaaaagga gcaggaatca ctgccgttgc agctattgtt
    42541 gaacacaata catcaggaat catctctcgt aaatctgata atgtaagcag tccaaaagac
    42601 ttggttggta agaaatatgg gacatggaat gacccaactg aacttgctat gttgaaaacc
    42661 ttggtagaat ctcaaggtgg agactttgag aaggttgaaa aagtaccaaa taacgactca
    42721 aactcaatca caccgattgc caatggcgtc tttgatactg cttggattta ctacggttgg
    42781 gatggtatcc ttgctaaatc tcaaggtgta gatgctaact tcatgtactt gaaagactat
    42841 gtcaaggagt ttgactacta ttcaccagtt atcatcgcaa acaacgacta tctgaaagat
    42901 aacaaagaag aagctcgcaa agtcatccaa gccatcaaaa aaggctacca atatgccatg
    42961 gaacatccag aagaagctgc agatattctc atcaagaatg cacctgaact caaggaaaaa
    43021 cgtgactttg tcatcgaatc tcaaaaatac ttgtcaaaag aatacgcaag cgacaaggaa
    43081 aaatggggtc aatttgacgc agctcgctgg aatgctttct acaaatggga taaagaaaat
    43141 ggtatcctta aagaagactt gacagacaaa ggcttcacca acgaatttgt gaaataatga
    43201 cagaaattag actagagcac gtcagttatg cctatggtca ggagaggatt ttagaggata
    43261 tcaacctaca ggtgacttca ggcgaagtgg tttccatcct aggcccaagt ggtgttggaa
    43321 agaccaccct ctttaatcta atcgctggga ttttagaagt tcagtcaggg agaattgtcc
    43381 ttgatggtga agaaaatccc aaggggcgcg tgagttatat gttgcaaaag gatctgctct
    43441 tggagcacaa gacggtgctt ggaaatatca ttctgcccct cttgattcaa aaggtggata
    43501 aggcagaagc tatttcccga gcggataaaa ttcttgcgac cttccagctg acagctgtaa
    43561 gagacaagta tcctcatgaa cttagcggtg ggatgcgcca gcgtgtagcc ttactccgga
    43621 cctacctttt tgggcacaag ctctttctct tagatgaggc ctttagcgcc ttggatgaga
    43681 tgacaaagat ggaactccac gcttggtatc ttgagattca caagcagttg cagctaacaa
    43741 ccctgatcat cacgcatagt attgaggagg ccctcaatct cagcgaccgc atctatatct
    43801 tgaaaaatcg ccctgggcag attgtttcag aaattaaact agattggtct gaagatgagg
    43861 acaaggaagt ccaaaagatt gcctacaaac gtcaaatctt ggcagaatta ggcttagata
    43921 agtagaaaaa tagggagttg gtgaagatta tcctttacca gcgccctttt tcttttaaaa
    43981 atgagaaaat ttcggtataa tagtcaaaca aggtcaaggt ttaaagagag aggtgggttt
    44041 gttatgagat ttaaaaatac atcggatcat attgaggcct acatcaaggc gattttagat
    44101 caatctggta tcgtggagtt gcaacggagt cagttggcag atacctttca ggttgttcct
    44161 agtcagatta actacgtgat caagacacgc tttacggaaa gtagaggcta cttggttgaa
    44221 agtaagcgtg gtggcggagg ctacattcgt ataggacgga ttgagttttc tagtcatcat
    44281 gaaatgctcc gggagctgct ttactcgatt ggtgagcgag tcagtcaaga aatttatgag
    44341 gatattctcc agcttttggt tgagcaggaa ttgatgacca agcaggagat gaatttgcta
    44401 gaatcagtag ctttggatcg cgttttagga gaagaagctc cagttgttcg agcaaacatg
    44461 ctacgtcaga tcatacaaga ggtagataga aaagggaagt aagatgaact attcaaaagc
    44521 attgaatgaa tgtatcgaaa gtgcctacat ggttgctgga cattttggag ctcgttatct
    44581 agagtcttgg cacttgttga ttgccatgtc taatcacagt tatagtgtag caggggcaac
    44641 tttaaatgat tatccgtatg agatggaccg tttagaagag gtggctttgg aactgactga
    44701 aacggactat agccaggatg aaacctttac ggaattgccg ttctcccgtc gtttgcaggt
    44761 tctttttgac gaagcagagt atgtagcgtc agtggtccat gctaaggtgc tagggacaga
    44821 gcacgtcctc tatgcgattt tgcatgatgg caatgccttg gcgactcgta tcttggagag
    44881 ggctggattt tcttatgaag acaagaaaga tcaggtcaag attgctgctc ttcgtcgaaa
    44941 tttagaagaa cgggcaggct ggactcgtga agatctcaag gctttacgcc aacgccatcg
    45001 tacagtagct gacaagcaaa attctatggc caatatgatg ggcatgccgc agactcctag
    45061 tggtggtctc gaggactata cgcatgattt gacagagcaa gcgcgttctg gcaagttaga
    45121 accagtcatc ggtcgggaca aggaaatctc acgtatgatt caaatcttga gccggaagac
    45181 taagaacaac cctgtcttgg ttggggatgc tggtgtcggg aaaacagctc tggcgcttgg
    45241 tcttgcccag cgtattgcta gtggtgacgt gcctgcggaa atggctaaga tgcgcgtgtt
    45301 agaacttgat ttgatgaatg tcgttgcagg gacacgcttc cgtggtgact ttgaagaacg
    45361 catgaataat atcatcaagg atattgaaga agatggccaa gtcatcctct ttatcgatga
    45421 actccacacc atcatgggtt ctggtagcgg aattgattcg actctggatg cggccaatat
    45481 cttgaaacca gccttggcgc gtggaacttt gagaacggtt ggtgccacca ctcaggaaga
    45541 atatcaaaaa catatcgaaa aagatgcggc actttctcgt cgtttcgcta aagtgacgat
    45601 tgaagaacca agtgtggcag atagtatgac tattttacaa ggtttgaagg cgacttatga
    45661 gaaacatcac cgtgtacaaa tcacagatga agcggttgaa acagcggtta agatggctca
    45721 tcgttattta accagtcgtc acttgccaga ctctgctatc gatctcttgg atgaggcggc
    45781 agcaacagtg caaaataaat caaagcatgt aaaagcagac gattctgact tgagtccagc
    45841 tgacaaggcc ttgatggatg gcaagtggaa acaggcagcc cagctaatcg caaaagaaga
    45901 ggaagtgcct gtctataaag acttggtgac agagtctgat attttgacca ccttgagtcg
    45961 cttgtcaggt atccccgttc aaaaactgac tcagactgat gccaagaaat acttaaactt
    46021 ggaagctgaa ctgcacaaac gtgtcatcgg tcaagaccaa gctgtttcaa gtattagtcg
    46081 tgccattcgc cgcaatcagt caggaattcg cagtcacaag cgtccgatcg gttcctttat
    46141 gttcctagga cccacaggtg tcggtaagac cgagttggcc aaggctttgg cagaagttct
    46201 ctttgatgac gaatcagccc ttatccgctt tgatatgagt gagtatatgg agaaattcgc
    46261 agccagccgt ctaaatggag ctcctccagg ctatgtgggt tacgaagaag gtggggagtt
    46321 gacagagaag gttcgcaata aaccctattc cgttctcctc tttgatgagg tagagaaggc
    46381 ccatccagat atctttaatg ttctcttgca ggttctggat gacggtgtct tgacagatag
    46441 caagggacgc aaggtcgatt tttcaaatac cattatcatt atgacatcga acttaggtgc
    46501 gactgccctt cgtgatgata agactgttgg ttttggggct aaggatattc gttttgacca
    46561 ggaaaatatg gaaaaacgca tgtttgaaga actgaaaaaa gcttatagac cggaattcat
    46621 caaccgtatt gatgagaagg tggtcttcca tagcctatct agtgaccata tgcaggaagt
    46681 ggtgaagatt atggtcaagc ctttagtggc aagtttggct gaaaaaggca ttgacttgaa
    46741 attacaagct tcagctctga aattgttagc aaatcaagga tatgacccag agatgggagc
    46801 tcgcccactt cgcagaaccc tgcaaacaga agtggaggac aagttggcag aacttcttct
    46861 caagggagat ttagtggcag gcagcacact taagattggt gtcaaagcag gccagttaaa
    46921 atttgatatt gcataaaaga ataaaagtac cagcatctga ccataagtca cagtggagtg
    46981 aaactcaatg aaaatcaaag agcaaactag gcagctagcc gcaggttgct caaaacactg
    47041 ttttgaggtt gcagatagag ctgacgtggt ttgaagagat ttttgaagag tataagctgc
    47101 aagatgaatg attttcttgt attgacgttg ttgttgacaa aaagtagcgg ataaatgaaa
    47161 tccattccat tatcatagat gataggctgg taggaaattt tcaaatagca tacagaaaat
    47221 agatgtatgg agttctggta gtagaaaggg agagagatga acattttagt tgcagatgac
    47281 gaggaaatga ttagagaagg aattgcagca tttctgacag aagagggtta tcatgtcatt
    47341 atggctaagg atggacaaga ggtcttggaa aaatttcaag atctccctat ccatctcatg
    47401 gtactggatt taatgatgcc taggaagagt ggttttgaag tgttaaaaga aatcaatcaa
    47461 aagcacgata ttcctgtcat cgtcttgagt gctctgggag atgaaactac tcagtcacag
    47521 gtatttgatc tctatgctga tgatcatgtg acaaaacctt tttctttggt actgcttgtc
    47581 aagcgtatta aggcgcttat cagacgttac tacgtcatag aggatctttg gcgatatcag
    47641 gatgtaacag tggattttac ctcttacaaa gcacattata aaaatgaaga aattgatctc
    47701 aaaccaaagg aattactggt actaaagtgt ttgattcagc ataaaaatca agttttaagt
    47761 agagagcaga tattggaaga aatttcaaaa gatgtagctg atttaccttg tgatagggtc
    47821 gttgatgtct atattcgtac tcttcgcaaa aaattagctt tagattgtat cgtgactgtg
    47881 aaaaatgttg ggtataagat tagcttatga taaaaaatcc taaattatta accaagtctt
    47941 ttttaagaag ttttgcaatt ctaggtggtg ttggtctagt cattcatata gctatttatt
    48001 tgacctttcc tttttattat attcaactgg agggggaaaa gtttaatgag agcgcaagag
    48061 tgtttacgga gtatttaaag actaagacat ctgatgaaat tccaagctta ctccagtctt
    48121 attcaaagtc cttgaccata tctgctcacc ttaaaagaga tattgtagat aagcggctcc
    48181 ctcttgtgca tgacttggat attaaagatg gaaagctatc aaattatatc gtgatgttag
    48241 atatgtctgt tagtacagca gatggtaaac aggtaaccgt gcaatttgtt cacggggtgg
    48301 atgtctacaa agaagcaaag aatattttgc ttttgtatct cccatataca tttttggtta
    48361 caattgcttt ttcctttgtt ttttcttatt tttatactaa acgcttgctc aatcctcttt
    48421 tttacatttc agaagtgact agtaaaatgc aagatttgga tgacaatatt cgttttgatg
    48481 aaagtaggaa agatgaagtt ggtgaagttg gtgaagttgg aaaacagatt aatggtatgt
    48541 atgagcactt gttgaaggtt attcatgagt tggaaagtcg taatgagcaa attgtaaaat
    48601 tgcaaaatca aaaggtttcc tttgtccgtg gagcatcaca tgagttgaaa acccctttag
    48661 ccagtcttag aattatccta gagaatatgc agcataatat tggagattac aaagatcatc
    48721 caaaatatat tgcaaagagt ataaataaga ttgaccagat gagccgctta ttggaagaag
    48781 tactggagtc ttctaaattc caagagtgga cagagtgtcg tgagaccttg actgttaagc
    48841 cagttttagt agatatttta tcacgttatc aagaattagc tcattcaata ggtgttacaa
    48901 ttgaaaatca attgacagat gctaccaggg tcgtcatgag tcttagggca ttggataagg
    48961 ttttgacaaa cctgattagt aatgcaatta aatattcaga taaaaatggg cgcgtaatca
    49021 tatccgagca agatggctat ctctctatca aaaatacatg tgcgcctcta agtgatcaag
    49081 aactagaaca tttatttgat atattctatc attctcaaat cgtgacagat aaggatgaaa
    49141 gttctggttt gggtctttac attgtgaata atattttaga aagctatcaa atggactata
    49201 gttttctccc ttatgaacac ggtatggaat ttaagattag cttgtagaca gattagtttt
    49261 ttattaaagt tcatataggg ttaacataag tgtgttattc tttgtgtaga taaaagaaag
    49321 gatactaata tggtattagc gattatttta gtaacattct ttattcgatt gattttttta
    49381 aagcgttcga tagagaatga gaaacgaatc cttagcaatg gcgggaaaga atttggagtt
    49441 gagaatacaa aacgattaac tatggctcat attgtttttt atctctcttg cttggttgag
    49501 gcaatggtgc acaagacaat ttttgatggc atgggcatgg ttggtttggt cttgcttatt
    49561 ttttctatgc tgatgttgat gttggtgatt cacttgttgg gagatatttg gacagtgaag
    49621 cttatgcttg tcaataatca caaatatgta gatcatatct tgtttaggac agtaaaacac
    49681 cctaattact ttttaaatat tttacctgag ttgattggct tgaccttgtt gagtcatgct
    49741 tatgtgactt ttgttttagt ttttccagtt tatgcagtta ttttgtatcg acgaatagct
    49801 gaagaggaaa agctattaca tgaagttata atcccaaatg gaagcataaa gagataaata
    49861 caaaattcga tttatataca gttcatattg aagtgatata gtaaggttaa agaaaaaata
    49921 tagaaggaaa taaacatgtt tgcatcaaaa agcgaaagaa aagtacatta ttcaattcgt
    49981 aaatttagta ttggagtagc tagtgtagta gttgctagct tgttcttagg aggagtagtc
    50041 catgcagaag gggttagaag tgagaataac cccacggtta catctagtgg gcaagatata
    50101 tcgaagaagt atgctgatga agtcaagtca catctagaaa aaatattgag tgagatccaa
    50161 acaaatttag atagaagtaa acatatcaaa actgtaaatc taattaacaa attgcaagac
    50221 attaagagaa cgtatttgta tgaattaaat gttttagaag ataagtcgaa agctgagttg
    50281 ccgtcaaaaa taaaagcaga gttagacgca gcttttgagc agtttaaaaa agatacatta
    50341 ccaacagaac caggaaaaaa ggtagcagaa gctaagaaga aggttgaaga agctgagaaa
    50401 aaagccaagg ctcaaaaaga agaagattac cgtaactacc caaccattac ttacaaaacg
    50461 cttgaacttg aaattgctga gtccgatgtg aaagttaaag aagcggagct tgaactagta
    50521 aaaaaggaag ctgacgaatc tcgaaacgag ggcacaatta accaagcaaa agcgaaagtt
    50581 gagagtgaac aagctgaggc tacaaggtta aaaaaaatca agacagatcg tgaaaaagca
    50641 gaagaagaag ctaaacgaag agcagatgct aaagagcaag atgaatcaaa gaggcgaaag
    50701 agtcgggtaa aacgaggaga tcttggagag ccagcaacac ctgataaaaa agaaaatgat
    50761 gcgaagtctt cagattctag cgtaggtgaa gaaactcttc caagcccatc cctgaaacca
    50821 ggaaaaaagg tagcagaagc tgagaagaag gttgaagaag ctgagaaaaa agccaaggat
    50881 caaaaagaag aagatcaccg taactaccca accattactt acaaaacgct tgaacttgaa
    50941 attgctgagt ccgatgtgga agttaaaaaa gcggagcttg aactagtaaa agaggaagct
    51001 aagggatctc gaaacgagga aaaagttaag caagcaaaag cggaagttga gagtaaaaaa
    51061 gctgaggcta caaggttaga aaaaatcaag acagatcgta aaaaagcaga agaagctaaa
    51121 cgaaaagcag cagaagaaga taaagttaaa gaaaaaccag ctgaacaacc acaaccagcg
    51181 ccggctcctc aaccagaaaa accagctcca gctccaaaac cagagaatcc agctgaacaa
    51241 ccaaaagcag aaaaaccagc tgatcaacaa gctgaagaag actatgctcg tagatcagaa
    51301 gaagaatata atcgcttgac tcaacagcaa ccgccaaaaa ctgaaaaacc agcacaacca
    51361 tctactccaa aaacaggctg gaaacaagaa aacggtatgt ggtacttcta caatactgat
    51421 ggttcaatgg cgacaggatg gctccaatac aatggttcat ggtactacct caacgctaat
    51481 ggtgatatgg cgacaggatg gttccaatac aatggttcat ggtactacct caacgctaat
    51541 ggtgatatgg cgacaggatg gctccaatac aatggttcat ggtactacct aaacagcaat
    51601 ggtgctatgg taacaggatg gctccaatac aatggttcat ggtactacct caacgctaac
    51661 ggttcaatgg caacagattg ggtgaaagat ggagatacct ggtactatct tgaagcatca
    51721 ggtgctatga aagcaagcca atggttcaaa gtatcagata aatggtacta tgtcaatggc
    51781 tcaggtgccc ttgcagtcaa cacaactgta gatagctata gagtcaatgc caatggtgaa
    51841 tgggtaaact aaacctaata taactcgtta atgctggctt cctgtaagaa ctctttaaag
    51901 tattccctac aaataccata tcctttcagt agataatata cccttgtagg aagtttagat
    51961 taaaaaataa ctctgtaatc tctagccgga tttatagcgc tagagactac ggagtttttt
    52021 tgatgaggaa agaatggcgg cactcaagag actctttaag agagttacgg gttttaaact
    52081 attaagcctt ctccaattgc aagagagctt caatctctgc cagggtgcta gcttgcgaaa
    52141 tggctccacg gagtttggca gcgccagatg ttccacggag gtagtgagga gcgaggccac
    52201 ggaattcacg aactgcgacg ttttctcctt tgaggttaat caatcgtttc aagtgttcgt
    52261 aggcgatctt catcttgtct tcaaaggtca aatcaggtag gatttctcct gtttcaaagt
    52321 aatggttgat ttggttgaag aggtaaggat ttcccatggc agctcggcca atcatgactg
    52381 cgtcagcacc aacttcttcg atgcgttgct tggcttcttg gacagtacgg atatcaccgt
    52441 tggcgatgaa tggaatcttg gttagagctt gggcaacctt gtacagggtc tcaaggtctg
    52501 cgtggccagt atacatttgt tcacgggtac ggccatgcat ggcgagggca gaaacacctg
    52561 cagcctcagc agcgagggca ttttctactg ccagagatgg gtccgcccag ccggtacgca
    52621 ttttgacagt aagtgggata tcaaggacag actggacctt gttgatgata gagtagatct
    52681 tgtcaggatc cttgagccac atagctccag cttcgttctt cacgattttg ttgacagggc
    52741 agcccatgtt gatatcgacg atatcggtct tggtgttttc ttggatgaat tctgctgcgc
    52801 gtgctaggct gtcttcatcg ctaccaaaaa gttggataga gacagggttt tcgccctcat
    52861 cgatatgaag catgtgcagg gttttttcgt tgttgtattg gattcccttg tcagagacca
    52921 tttccattac aacgagtcca gctccgagct cttttgcgat ggtacgaaag gctgagttgg
    52981 tcacgccagc cataggcgct aaaacggtac gattgggaat ctcaacattg ccaatcataa
    53041 aaggtgtatt aagatttgtc acgaatgagt tcctccaggt ccttttcatc aaagttgtaa
    53101 gtagtttggc agaattgaca agtgatttct accccgtggt cttcctcttt catttcctgt
    53161 aagtctgagc ttggaaggct ggcaagagcg ttcataaagc gttcatggct acagtcacat
    53221 tggaaacgga tttcttcttc agaaagacgc ttgtaggctt cgtccccgta gatagccttg
    53281 aggagggctt cgatatggtc gtcgctttcg agaagagtag agatagctgg catttcttgg
    53341 atgcgttttt caaagcgagc aatctcttct ttcttggctc ctggcaagac ttgaactagg
    53401 aaaccacctg caaccttgac cttgtcttcc tcgtccaaaa ggacattgag gccgaccgct
    53461 gaaggcgttt gttggctttc agtaaggtaa aaggcaaggt cttcaccgat ttctccagag
    53521 atgaggggag ttatagagtt gtaaggattt ccagcaccgt agtctgtgat aacgaggaat
    53581 tgaccatttc caacaaaagg tccgactagg acttcaccag tcgcagtctt tttgatgtca
    53641 acaccaggat tttgaacata gcctttgacg ttccccttgg tatcagcgac ggtgataata
    53701 gcacctagag agctagagcc caacacctta actgtaagtt tggtatttcc tttttcattg
    53761 gctgcgagaa tctggctggc gataagagtt cgaccaagcg ctacagttga gctagcttgg
    53821 gtttgatgtt tttcttgagc agtgcggacg gtttccgtgc tatcaaggac aaaagcacga
    53881 aaggctccgc tttctgatat agttttaata attttatcca tagctactat tttagcataa
    53941 aaatgcccaa agggggagcc gtgtgtttac tgattttcag gataatggac caggaaatca
    54001 gcatgaaaat aaaaagagaa acagattatt ttagcatttg taagatttat gctatgctta
    54061 aggtagaaaa tgaaaggggt aacaaatgta tttaggagat ttgatggaga aagccgagtg
    54121 tggtcaattt tcaatccttt cctttctatt acaagagtct cagacgaccg tcaaggctgt
    54181 aatggaagaa acaggatttt caaaagcaac cctaaccaaa tatgtcaccc tgctcaatga
    54241 caaggctttg gatagtggct tagagctggc tattcactca gaagatgaaa atctgcgtct
    54301 gtctatcggt gcagctacca aggggagaga tattcggagc ttgtttttgg agagtgctgt
    54361 taaataccag attttggttt atcttctcta ccaccaacag tttttagccc atcagctggc
    54421 tcaagaattg gtgattagcg aggctacgct tggtcgtcac ttggctggtt taaatcagat
    54481 tttgtcagaa tttgatttat ccatccaaaa tggacgttgg cgaggtccag agcatcagat
    54541 tcgctatttc tatttctgtc ttttccgaaa ggtctggtcg agtcaggaat gggaaggtca
    54601 catgcagaaa ccagagagaa aacaggagat tgccaattta gaggaaatct gcggtgcaag
    54661 tttgtctgtg gggcagaaat tggacttggt tctctgggct cacatcagtc aacaacgtct
    54721 tcgggtcaat gcttgtcagt ttcaagtcat agaagagaaa atgcgagggt attttgacaa
    54781 tattttctac cttcgtttgc tgagaaaggt tccgtccttt tttgctgggc aacatattcc
    54841 actaggagtt gaggatggtg agatgatgat attcttctct tttctcctat ctcatcgcat
    54901 tcttcctctt catactatgg agtatattct tggttttgga gggcagttgg cagatttact
    54961 gacgcaattg attcaagaaa tgaagaagga ggaactattg ggggattata cagaggacca
    55021 tgtcacctat gaactcagtc agctttgtgc tcaagtctat ctctataagg gctatatttt
    55081 acaggatcgc tacaagtacc agttagagaa tcgtcatcca tatttactga tggaacatga
    55141 ttttaaagag acagcagagg agatttttca tgctctacct gcttttcaac aggggacaga
    55201 tttagataag aagattctct gggaatggct ccagttaatc gaatatatgg ctgaaaacgg
    55261 tggccagcat atgcggattg gtctggattt gacatctggt tttcttgtct tttcaaggat
    55321 ggcagccatt ttgaaacggt atttggaata caatcgtttt attaccattg aagcctatga
    55381 ccctagtcgg cattatgatt tgctggttac caataacccg attcataaga aggaacagac
    55441 accagtctat tatttaaaaa atgacttgga tatggaggat ttggtagcga ttcgccagtt
    55501 attattcact taaaaggctt ggttaatcca ggtctttttt gtgaaattca cacaatctcc
    55561 tcacattttt ttaaaaatta aaaaaagttg ataaacaaga aagcgcttta ttttgtatac
    55621 tagtaagtgt aaagaggaaa cacctcaaga tctttatcag gaggacagta catgtcacaa
    55681 gaaaaataca tcatggccat tgaccaggga actacaagtt ctcgtgccat cattttcaac
    55741 aaaaaagggg aaaaggttag ctcgagtcaa aaagagttta cccagatttt ccctcaggca
    55801 ggttgggttg agcacaatgc caatgaaatt tggaactctg ttcagtcagt tattgcgggt
    55861 gctttcatcg aaagtggtgt caagccaaat caaatcgagg caatcgggat taccaaccaa
    55921 cgtgaaacaa cggttgtctg ggataagaaa acaggacttc ctatctacaa tgctatcgtt
    55981 tggcagtcac gccagacagc acctttggct gagcaactaa aaagccaagg ttatgtggaa
    56041 aaattccatg aaaagactgg tttgattatt gatgcttact tctctgctac caaggttcgt
    56101 tggattttgg atcatgtaga aggtgctcaa gagcgagcag aaaaagggga attgctcttt
    56161 ggtactatcg atacttggtt ggtttggaaa ttgactgacg gtgcggctca cgtgactgac
    56221 tactcaaatg cagctcgtac catgctttat aacattaaag aactcaaatg ggatgatgag
    56281 attttggaaa tccttaacat tccgaaggct atacttccag aagttcgttc taactccgaa
    56341 atctacggca agacagctcc attccatttc tacggtggag aggtgccaat ctcaggtatg
    56401 gctggggacc aacaagcagc cctctttgga cagttggctt ttgagccagg tatggttaag
    56461 aatacttatg gaacaggctc tttcatcatc atgaatactg gggaagagat gcagttgtct
    56521 gaaaacaacc tcttgacaac cattggttac ggaatcaacg gtaaggttta ttatgccttg
    56581 gaaggttcta tcttcatcgc aggaagtgct attcagtggc ttcgtgacgg tcttcgcatg
    56641 gttgaaaatt caccagaatc tgaaaaatac gctcgtgatt ctcacaacaa cgatgaagtt
    56701 tatgtcgttc cagcctttac aggtctaggc gctccatact ggaaccaaaa tgctcgtggt
    56761 tccgtctttg gtttgactcg tggaacaagc aaagaagact ttatcaaggc gactttgcaa
    56821 tctattgctt atcaagtgcg tgatatcatc gacaccatgc aagtggatac tcagaccgcc
    56881 attcaagtac tgaaggtgga tggtggtgca gccatgaaca acttcctcat gcagttccag
    56941 gcggatattt taggcattga cattgcacgt gctaaaaact tggaaacaac agctctagga
    57001 gcggccttcc tagcaggttt gtcagtaggg tactggaaag acttggacga gttgaaactc
    57061 ttgaacgaga caggagaact ctttgagcca tctatgaacg aatctcgcaa ggaacaactc
    57121 tacaagggct ggaagaaggc tgtgaaagca actcaagtct ttgcggaagt agacgactaa
    57181 tactggcaga ataaagcgat ttatttagaa agtgtgtaaa tatggaattt tcaaaaaaaa
    57241 cacgtgaatt gtcaattaaa aaaatgcagg aacgcaccct ggacctcttg attatcggtg
    57301 gaggaatcac aggagctggt gtagccttgc aggcggcagc tagcggtctt gagactggtt
    57361 tgattgaaat gcaagacttt gcagaaggaa catctagtcg ttcaacaaaa ttggttcacg
    57421 gaggtcttcg ctacctcaaa caattcgacg tagaagtggt ctcagatacg gtttctgaac
    57481 gtgcagtggt tcaacaaatc gctccacaca ttccaaaacc agatccaatg ctcttaccag
    57541 tttacgatga agatggagca acctttagcc tcttccgtct taaagtagcc atggacttgt
    57601 acgacctctt ggcaggtgtt agcaacacac caactgcgaa caaggttttg agcaagaaag
    57661 aagtcttgga acgccagcca aacttgaaga aggaaggctt ggtaggaggt ggagtgtatc
    57721 ttgacttccg taacaacgat gcgcgtctcg tgattgaaaa catcaaacgt gccaaccaag
    57781 acggtgccct cattgccaac cacgtgaagg cagaaggctt cctctttgac gaaagtggca
    57841 agattacagg tgttgtagct cgtgatctct tgacagatca agtatttgaa atcaaggccc
    57901 gtctggttat taatacaaca ggtccttgga gtgataaagt acgtaatttg tctaataagg
    57961 gaacgcaatt ctcacaaatg cgcccaacta agggagttca cttggtagtg gattcaagca
    58021 aaatcaaggt ttcacagcca gtttacttcg acacaggttt gggtgacggt cgtatggtct
    58081 ttgttctccc acgtgaaaac aagacttact ttggtacaac tgatacagac tacacaggtg
    58141 atttggagca tccaaaagta actcaagaag atgtagatta tctacttggc attgtcaaca
    58201 accgctttcc agaatccaac atcaccattg atgatatcga aagcagctgg gcaggtcttc
    58261 gtccattgat tgcagggaac agtgcctctg actataatgg tggaaataac ggtaccatca
    58321 gtgatgaaag ctttgacaac ttgattgcga ctgttgaatc ttatctctcc aaagaaaaaa
    58381 cacgtgaaga tgttgagtct gctgtcagca agcttgaaag tagcacatct gagaaatatt
    58441 tggatccatc tgcagtttct cgtgggtcta gcttggaccg tgatgacaat ggtcttttga
    58501 ctcttgctgg cggtaaaatc acagactacc gtaagatggc tgaaggagct atggagcgcg
    58561 tggttgacat cctcaaagca gaatttgacc gtagctttaa attgatcaat tctaaaactt
    58621 accctgtttc aggtggagaa ttgaacccag caaatgtgga ttcagaaatc gaagcctttg
    58681 cgcaacttgg agtatcacgt ggtttggata gcaaggaagc tcactatctg gcaaatcttt
    58741 acggttcaaa tgcaccgaag gtctttgcac ttgctcacag cttggaacaa gcgccaggac
    58801 tcagcttggc agataccttg tcccttcact atgcaatgcg caacgagttg gctcttagcc
    58861 cagttgactt ccttcttcgt cgtaccaacc atatgctctt tatgcgtgat agcttggata
    58921 gcatcgttga gccagttttg gatgaaatgg gacgattcta tgactggaca gaagaagaaa
    58981 aagcaactta ccgtgctgat gtcgaagcag ctctcgctaa caacgattta gcagaattaa
    59041 aaaattaaga aaaaataaaa gaggtggagg gcagcattcc ttgtcgcccg tcccttcttt
    59101 ttaatggaga cagaaagatg atgaatgaat tatttggaga atttctaggg actttaatcc
    59161 tgattcttct aggaaatggt gttgttgcag gtgtggttct tcctaaaacc aagagcaata
    59221 gctcaggttg gattgtgatt actatgggtt gggggattgc agttgcggtt gcagtctttg
    59281 tatctggcaa gctcagtcca gctcatttaa atccagctgt gacagttggt gtagctttaa
    59341 aaggtgactt gccttgggct tccgttttgc cttatatctt agcccagttc gcaggggcca
    59401 tgctgggtca gattttggtt tggttgcaat tcaaacctca ctatgaggca gaagaaaatg
    59461 caggcaatat cctggcaacc ttcagtactg gaccagccat caaggatact gtatcaaact
    59521 tgattagcga aatccttgga acctttgttt tggtgttgac aatctttgct ttgggtcttt
    59581 acgattttca ggcaggtatc ggaacctttg cagtgggaac tttgattgtc ggtatcggtc
    59641 tatcactagg tgggacaaca ggttatgcct tgaacccagc tcgtgacctt ggacctcgta
    59701 tcatgcacag catcttgcca attccaaaca agggagacgg agactggtct tacgcttgga
    59761 ttcctgttgt aggccctgtt atcggagcag ccttggcagt gcttgtattc tcacttttct
    59821 agtttatact cttcgaaaat caaattcaaa ccacgtcagc gtcgccttac cgtactcaag
    59881 tacagcttgc ggctagcttc ctagtttgct ctttgatttt cattgagtat tagaaaacaa
    59941 ttatgttgat agagcttggg caagagccca atttcagcaa aaaatgaagt aaatcttctc
    60001 ataataaaac gcatcatatc aagcacgaaa attccacgag gtcaactaca gtcagaaagc
    60061 tgaacaacaa gccaaaacgc ccaaaaaagg cggcaaaaag caagcacctg caagcaacgt
    60121 gccgaaatgg tcaaatcctg attatgtcaa cgaattagac ccaaaaatcg ttgatatgct
    60181 agtagaattt cacaagtcac aaggcacttt ggaaactccc gaggcgcaag cagaaatcgc
    60241 ccaaaaacgt gaagaaatcg agcaaaggag agctgagctt gaggataaaa aacaagagct
    60301 tttgaaccgc ttgaacaaat agagtttcgc aagtattatg cttacaaatt acttgagcaa
    60361 ttaactaaaa tataaaccct gcctagatat aaaggcaggg tttatatttt agaaattcac
    60421 gtaggttgtt acggttttta catacccagt atagtttgag tttctatagt attcagtgat
    60481 aaacttccat tttctttgag caacatggat ataagtactt gttatgtagt atggatatgg
    60541 gctttgtgaa tccaagtaag actgataagc ttgtatacca aaatatgctc caccaattat
    60601 tgcaccccat ggacccccca ataaagcacc tatcctacca atcatataac tgattccagc
    60661 accagtcatg aagttagcga atgtgttagc ttgtttattc ccatgtattg tgttgacgta
    60721 attccaaaca ttaggatcgt atgatctaaa agatatattt aggtcgattt cattcttttg
    60781 ataagccata taaaatgccc cattgatata gacgccgtca gcacgtcgtt caatagtgtc
    60841 tacacttcca tctggattga caacctcaag aacttcatcg cttaaaatat ttacttgcgt
    60901 atctccgaac cgcactgatg agccattctc aaactgagcc tcaccagata caactttaga
    60961 gtttgccgat aagctatcat cagcaaaaac aacaagcgac ggggaaatgc tagacataca
    61021 gaaaacagac ataactagca aacacatgca tttaaacatc ttagacataa cggaaactct
    61081 tttgtatttt tgattttttt caacttttat tatacaataa aaccaaataa aaagaaagcg
    61141 gtaacaatat gcttaatgcg aaaatttttt atatattttt atgtttgatc gttatcgaaa
    61201 ctacaggctt gttgttgttg aaaagaggtc tcgaaatggg ttatttagac acagaagcta
    61261 ttatcctcgc agttttttca tttgcttttt acaacctatg ttcattcgct tgggtctgct
    61321 ctacaataaa aaataaatag acgtattttc aaaaaaaaaa aaatgaatat ttatattagc
    61381 aaaatgacga tttaaatcgt cgtttttttg tagtacgacg ggcatgtcgt atatctgagg
    61441 tgtaagtcct cggtgggcac ctgctaccgg tgaacccaat agcgattccc aagcctgact
    61501 atcgtgaggt agcggattaa aacggtctgg ggatagaccg ttttaagtct gacgcaggaa
    61561 ataagaatcg tcagaggaag ggatagcgaa atcgtggctc tacgaacagg aacgtgatag
    61621 taaggcgtat atagcggata aggaggcttc aaactctaaa gtccaaaaag gtagtcgtaa
    61681 cctatatgtg taaatcacga gagtaattga attcggacta aggtttgtgt gaaaaagata
    61741 aatctttcta gagtctaaag actctgcgtc agatttccta ttttcactgt aaccttttaa
    61801 cgtcctcata tcttgtataa acgaggaaag atgtacgact tatcccgtga ggtttcatga
    61861 gcgctgaaag cgtagtaaca acgaatcatg agaagtcagc cgagcccata gtagtgagga
    61921 aacttctgta gtggaagtgg agcgaagggg tgaatactca aacagtctgg ggagagactg
    61981 tttgaggtct gtcgctagaa agagaaaacg acagatcgaa gtaatcctac ttcacttgtg
    62041 tctgtaaaat gagtggtctg atagaactgg actttgacac gtaatgacta gatgaaggtt
    62101 caccaatata agatgtccct caggcaccaa aacaagaaag gaatacgcac atgtcaaaac
    62161 tgctagataa gatattatca cgcgaaaata tgctggaagc ctacaatcaa gtaaaatcca
    62221 ataaaggctc agctgggatt gatggaatga ctatcgaaga gatggataat tatctcagac
    62281 aaaactggcg cttgactaag gaactgataa aacagagaaa atataagcct caaccagttc
    62341 ttaaagttga gatacctaaa ccagacggag gcatccgtca actaggaatt tcaacagtta
    62401 tggatagaat gattcaacag gccattgtcc aagtcatgag ccccatttgt gaaccccatt
    62461 tctcagatac gagttatggt ttcagaccaa ataggtcatg tgaaaaagcc atcatgaagc
    62521 tcttagaata cttaaatgac ggctatgagt ggatagtgga tatagaccta gagaaatttt
    62581 tcgatacagt tcctcaagat agattgatgt ccttagtaca taacattatc gaagacggag
    62641 atacggaatc cttgattcgt aagtatcttc attcaggtgt tatcattaat ggtcaacgtt
    62701 ataaaacact agttggtaca ccacagggag gaaatttatc tcctctctta tccaatatca
    62761 tgcttaatga attggacaag gaattagaaa agaggggact tcgatttgtg cgctacgcag
    62821 atgattgtgt gattacggtc gtaagcgagg cagccgctaa gcgtatgatg tattcagtca
    62881 gtcgttttat tgaaaaacgg ctaggtttga aagcaaacat gaccaagact aagattacca
    62941 gaccaagaga gttgaaatat ctaggttttg ggttctggaa atcatcagat ggttggaaaa
    63001 gtcgtccaca tcaagatagt gttcggagat ttaagcttaa attgaagaaa ctaacacaga
    63061 ggaaatggag tatagaccta acaagacgta ttgagcaact gaatttgtct attcgaggat
    63121 ggataaacta tttctcattg ggaaatatga aaagtatagt cgccagcata gatgagcgct
    63181 tgcgtactcg cctacgagtg attatctgga agcaatggaa gaagaaatcg agacgattat
    63241 ggggattgct taagttaggg gttcctaaat ggatagcaga taaggtatct ggctggggcg
    63301 accattatca attagtagct cagaagtcgg tacttaaacg tgctatatca aaaccagtcc
    63361 tggaaaaacg tggactggtt tcgtgtttgg attattacct tgaacgacat gcgttaaaag
    63421 ttagttgaac cgctgtatgc cgaacggcac gtacggtggt gtgagagggg ctagagatta
    63481 tcccctactc gattaactcc cctgaaattt attttaatta tgcaaatttc acgtattttt
    63541 gatgctgaga cgacgatcct gggaactttt cagatatttt tttgactatc taaatctatc
    63601 attagaaaag cttagagcgc caaaggattt gagcgttttt ctgattttta agactttttc
    63661 cagtctcttt ttcgattgaa gatgtaatta ttctactaac taactaactt cttagtacta
    63721 gccaacaacg ataatcataa ttcctcctaa aattaggaat aataaaggca atagtttttg
    63781 ttttttcatg taaaaaacct cacttttgtt ttctgctatt ttatgctaaa atattaaaaa
    63841 tcaaatttaa ttccaaagtt tgtaactaaa gggggagcgc tacatgtcta attcatttgt
    63901 caagttgtta gtctctcaat tatttgcaaa tttagcagat attttcttta gagtaacaat
    63961 cattgctaac atatacatta tttcaaaatc agtaattgcc acatcactag ttcctatctt
    64021 aataggaata tcctcttttg ttgcgagtct tttagttccg ttggttacta aaaggttagc
    64081 gctaaatagg gttttatctt tatctcaatt tggaaagact atattattgg cgatactggt
    64141 aggaatgttt accgtaatgc aatccgtagc gcctttggtg acctatctat ttgttgttgc
    64201 aatttccata ctagatggtt ttgcagcacc tgtttcctat gctattgtgc cacgctatgc
    64261 gaccgatttg ggtaaggcta attcagcctt atcaatgact ggtgaagctg ttcaattgat
    64321 aggttgggga ttaggtggac tcttgtttgc aacaattggt ctgttaccta ccacgtttat
    64381 cattttagtc ttgtatatca tttctagctt tctgatgtta tttcttccta acgctgaagt
    64441 ggaggtgtta gagtcagaaa ctaatcttga aattttgctc aaaggttgga agttagttgc
    64501 tagaaatcct agattaagac tttttgtatc agcaaattta ttggaaattt tttcaaatac
    64561 gatttgggtt tcttccatta tacttgtttt tgtaacggag ttattaaata aaacggaaag
    64621 ttactgggga tattctaata cagcatactc tattggtatt ataattagtg gcttaattgc
    64681 ttttaggcta tctgaaaagt tccttgctgc taaatgggaa agtattcttt ttcctcttgt
    64741 agctatggca atagtgacac tgactattct atattttcca aacgcacaga tgtttttatt
    64801 attttcagct ttagttggta tgttatcgca actaaaagaa gttcctgaaa gtgtatttct
    64861 tcaggaaaca gtagaggaaa atcatttagt taatgtctat tccgttcttg aagtgatttc
    64921 tacattagca ttttcagtat ttgttttgct aatgagctat attactgaga gttttggtat
    64981 tagcatcagt ttttggctat cagccatttg tctgatgata gaagctattt taatttatat
    65041 cagacgagat tattttaaat gagagagtgg ttaaaaagtc tttaaaaatc agaaaagcgc
    65101 atagtatcag gtgttgaaaa aacttgatat tgtgtgtttt attatgggaa gatttacttc
    65161 attgtctcct gaaatggagt tttgaagcag gatcactcta tttgaaaata tacatagaaa
    65221 aactgtataa tccttaaaat aagctgaaat ctattggaaa catacggtaa acaattgaaa
    65281 agatactata taaagtggta caatggtaga aaaataagct agtaagaatc actcttattt
    65341 tagcgaaaaa ttacagaaat gaatggtttt tcttgatgaa acagagaaaa gaattgtacc
    65401 tctttcttgg tcggacagcc ttgtattttc ttatctttct agggctgctt tacttcttta
    65461 gctatcttgg tcagggtcaa ggaagcttta tctataatga attttaactt gaaggagaat
    65521 ccctattgtg tcaaataaac caatagcaga tatgattgaa accattgagc attttgctca
    65581 gacacagcct agctatcctg tctataatgt tttggggcag gaacacactt atggcgattt
    65641 aaaggctgat tcggatagtt tggctgcagt cattgaccaa ctaggcttgc ctgagaagtc
    65701 tcctgtggtt gtttttggtg gccaagaata tgaaatgttg gcaacctttg tagcgctgac
    65761 taagtcaggt catgcctaca ttccaattga tagccattcg gccttggagc gagtttcagc
    65821 tattttagaa gtagcagagc caagcttgat tattgccatt tcagcctttc ccttggagca
    65881 ggtttctaca ccaatgataa atctagctca ggttcaagaa gcctttgccc aagggaataa
    65941 ctatgaaatc acgcatccag tcaagggaga tgataattac tacattatct ttacttctgg
    66001 tacgactggt aagcctaaga gagtgcagat ttcacatgat aatctcctca gctttacaaa
    66061 ctggatgatt acggataagg aatttgcgac accgagtcgt ccgcaaatgc tggcacagcc
    66121 accttattct tttgacttgt ctgtcatgta ttgggcaccg accttggcac ttggtggtac
    66181 gcttttcact cttccttcag tcatcactca ggactttaag caactctttg cggctatctt
    66241 ttcattgcca atcgctatct ggacatcaac accatccttt gcagatatgg ccatgttgtc
    66301 tgaatacttc aacagtgaga aaatgcctgg aatcactcat ttctactttg atggtgaaga
    66361 attgacggtc aaaacagctc aaaaactgcg cgagcgtttc ccaaatgccc atatcatcaa
    66421 tgcttacggc ccaacagaag cgacagtagc tctgtcagca gttgccgtga cagacgagat
    66481 gttagcgact ctcaaacgcc taccaatcgg ctataccaag gctgattctc caacctttat
    66541 cattgacgag gaaggaaata aactgccaaa tggtgagcag ggagaaatca ttgtttctgg
    66601 gccagctgtt tcaaaaggtt atatgaacaa tcctgaaaaa acagcagaag ccttctttga
    66661 gtttgaaaat ctgccagcct atcacacagg cgatgtggga accatgacag atgagggctt
    66721 gcttctctac ggcggacgca tggacttcca gattaagttc aacggttacc gcattgagtt
    66781 agaagatgtc tctcaaaacc tcaacaagtc tcgctttatc gaatctgctg tcgcagtacc
    66841 gcgctataac aaggaccaca aggtacaaaa tcgtcatctt aaaagacggt gttcgtgagc
    66901 agtttgagcg agatatcgat attaccaagg ccatcaagga agacctgaca gacatcatga
    66961 tgtcctacat gatgccatct aaattccttt accgagacag tttgccacta actccaaatg
    67021 gaaagattga catcaaagga ttgattaacg aggtgaataa gagatgatgg agttttttca
    67081 acagcttcct catttagagc catatggcaa tcctcagtat tttgtttatg tgattgctgc
    67141 aaccttgccc atctttatag gcctcttttt caagaaacgc tttgcctggt atgaagtgtt
    67201 ggtaagtctc ttctttattg tcaccatgtt ggtgggtgga aagaccaatc aactagctgc
    67261 cttgggtatt tacctttgct gggaaatatt gctcctgctt ttctacaagc attatcgaaa
    67321 aagcaaggat ggcaagtggg tcttctactt agttagtttt ctgtccctac ttccgattat
    67381 ctttgtcaag gtgcaaccag ctatcaatgg aacgcagtct ttgcttgggt tcttgggaat
    67441 ttcttacctg acctttcgtt cggttgggat tatcatcgag ctgagagatg gagtgattaa
    67501 ggattttacc ctctgggaat tcctccgttt ccttctcttc atgccaactt tctcgagtgg
    67561 tccaatcgat cgctttaagc gatttaatga aaattatcag accattcctg agcgagatga
    67621 gttgatggat atgctggatg aatctgtccg ctatatcatg cggggctttt tgtataagtt
    67681 tatcctagct catgttttag gagagacctt actacctcct ctgaagaatt tagccttgca
    67741 gtcaggtggc ttctttaatc tctatgcctt ggcagttatg tatacttttg gtctggagct
    67801 cttctttgac tttgcaggtt attctatgtt tgctttggcc atctcaaact tgatgggaat
    67861 ccgtagccct atcaacttta acaagccctt tttatcaagg gatttaaagg agttttggaa
    67921 tcgctggcat atgagtctgt ccttctggtt ccgtgacttt gtctttatgc gaatggtgat
    67981 ggtgttaacc agaaagaaag tctttaaaaa tcgtaatgta acctcaagca tggcctacat
    68041 tgtaaatatg ctgattatgg gattttggca tggcgtgacc tggtactata tcgcctatgg
    68101 actctttcat ggactaggtt tggtcatcaa tgatgcctgg gttcgcaaga aaaaaacgct
    68161 caataaggaa cggaaaaaag cagggaaggc tgccctacct gagaatcgct ggattcagtt
    68221 gcttggcatg gttgtcactt tccatgttgt catgttgtca ttcttaatct tttctggatt
    68281 cttgaataat ctatggttta aaaaataaaa ggaaataaaa tatggatatc aaatcagaag
    68341 ttatcgaaat tattgatgag ttgtttatgg aagatgtttc tgacatgatg gatgaagatc
    68401 tttttgatgc aggtgtcttg gatagtatgg gaacggttga gttgattgtg gagattgaga
    68461 accgttttga cattcgtgtc cctgtaacag agtttggtcg tgacgactgg aatacagcta
    68521 ataaaattat agctggtatt gtggagctac aaaatgctta aacgcttatg gatgatcttc
    68581 ggaccggtct tgatcgctgg tttgttggtt tttctgctca ttttctttta tcctactgag
    68641 atgcatcata atctaggagc tgaaaagcgt tcagcagtgg ctactactat cgatagtttt
    68701 aaggagcgaa gtcaaaaagt cagagcacta tctgatccaa atgtgcgttt tgttcccttc
    68761 tttggctcta gtgaatggct tcgttttgac ggtgctcatc ctgcggtatt agctgagaaa
    68821 tacaatcgtt cctaccgtcc ttatctttta ggacaggggg gagctgcatc gcttaaccaa
    68881 tattttggaa tgcaacagat gttacaacag ctggagaata aacaagttgt gtatgttatc
    68941 tcacctcagt ggttcagtaa aaatggctat gatccagcag ccttccagca gtattttaat
    69001 ggagaccagt tgactagttt tctgaaacat caatctgggg atcaggctag tcaatatgca
    69061 gcgactcgct tactgcaaca gttcccaaac gtagctatga aggacctggt tcagaagttg
    69121 gcaagtaaag aagaattgtc gacagcagac aatgaaatga ttgaattatt ggctcgtttt
    69181 aatgaacgcc aggcctcctt ttttggtcag ttttcggtta gaggctatgt taactacgat
    69241 aagcatgtag ctaagtattt aaaaatcttg ccagaccagt tttcttatca agcaatagaa
    69301 gatgttgtca aagcagatgc tgaaaaaaat acttccaata atgagatggg aatggaaaat
    69361 tatttctata atgagcagat caagaaggat ttgaagaaat taaaggattc tcagaaaagc
    69421 tttacctatc tcaagtcgcc agagtataat gacttgcagt tggttttaac acagttttct
    69481 aaatctaagg taaacccgat ttttatcatt ccacctgtta ataaaaaatg gatggactat
    69541 gctggtctac gagaggatat gtaccaacaa acggtgcaga agattcgcta ccagttagaa
    69601 agtcaaggtt ttaccaatat agcagatttt tctaaggacg gcggggagcc tttctttatg
    69661 aaggacacca ttcaccttgg ttggttgggt tggttggctt ttgacaaggc agttgatcct
    69721 ttcctatcca atcccacacc agctccgact taccatctga atgagcgctt tttcagcaaa
    69781 gattgggcga cttatgatgg agatgtcaaa gaatttcaat agataatata atatagaaga
    69841 gttcaagaat gaaactagtt ttcacgtttt ttcttgactc tttttttgct tgtgatataa
    69901 ttaactggta aacaaaatgt caaagaatag tatttttctc ttaaaaaaga gaagtctaaa
    69961 aggaaaggag tcagatatga gacagctagc aaaggatatc aatgcttttt tgaatgaggt
    70021 gattttgcag gcggaaaatc agcatgaaat cctaataggt cattgcacta gcgaggtggc
    70081 cctgaccaat actcaggagc atatccttat gctcttgtca gaggaatctt taacaaattc
    70141 agaattggct cgtcgtctca atgtcagtca ggcggcagtt accaaggcca ttaagtcttt
    70201 ggtcaaggaa gggatgttgg aaacatctaa agattctaaa gatgcgcgtg tgatttttta
    70261 tcagttgact gacttggctc gtccaatcgc tgaggagcac caccatcacc atgagcatac
    70321 acttttaacc tatgaacaag tggcgactca gtttactcca aatgaacaaa aagtgattca
    70381 gcggtttttg actgctttag taggagaaat caaataatga gatatattac ggtagaggat
    70441 ttgtccttct attatgataa ggagcctgtt cttgaacata tcaattattg tgttgatagt
    70501 ggggaatttg ttaccttgac tggggaaaat ggagcggcta agacgacgct catcaaggct
    70561 agtcttggaa ttctgcaacc acgcattgga aaggtggcta tttcaaagac aaatacgcaa
    70621 ggtaagaaat tgagaatagc ctatcttcct caacaaattg ccagttttaa tgctggtttt
    70681 ccaagtacgg tctatgaatt tgtcaagtcg ggtcgctatc cgagaaaagg ctggttccgt
    70741 cgtttgaatg ctcatgatga ggagcatatc aaggctagtc tggactcagt tggcatgtgg
    70801 gaacatcgag acaaacgctt ggggtctcta tctgggggac aaaagcagcg agcggtaatt
    70861 gcgcgtatgt ttgcttctga ccctgatgtg tttatcctag acgagccgac aacggggatg
    70921 gatgcaggaa gtaaaaatga attttacgaa ctcatgcacc acagcgccca tcatcatggc
    70981 aaggctgttt tgatgattac ccatgaccct gaagaagtta aggattatgc ggatcgcaat
    71041 attcatctag tccgtaacca agactcgcca tggcgttgtt tcaatgttca tgagaatggc
    71101 caggaggtgg gccatgctta gtttattatc ttacgacttt atacagcgcg cctttttggc
    71161 ggttattgct atgagtcttt tctcaccggt attgggaacc ttcctcatct tgcgtcgtca
    71221 gagtttgatg agtgataccc ttagccacgt ctcactttca ggtgtagcct ttggtctggt
    71281 tttggggatt tctccaactg tttctactat tgccattgtc ttgattgcgg cggtctttct
    71341 ggagtatctc cgtacggttt acaagagctt tatggaaatc gggacagcta tcctcatgtc
    71401 aacaggtctg gctgtttctc tgattgtcat gagcaagggt aaaagctcga gttcaatgag
    71461 tttggaccaa tatctctttg gttcgatcgt gactatcagt gaagaacagg tcatttccct
    71521 ctttgtcatt gcggtggttg ttttgatttt gacctttctc tttcttcgtc ctatgtatat
    71581 cttaactttt gacgaagata cggcctttgt ggatggcttg ccagttcgta ccatgtccat
    71641 tctttttaac atggtgacag gggtggctat tgcccttatg attcctgcag caggagctct
    71701 tctggtatcg accattatgg tcttgccagc tagtattgcc ctgcgtctgg ggaaaaactt
    71761 taaatcggtt atgctgcttg ccagtgcgat tggctttttg ggaatggtag caggacttta
    71821 catttcctac tatgcagaaa cacctgcaag tgcaagtatt accattattt ttgtaactgt
    71881 ctttatacta atcagtttag taagacgttt tatcaaatag gagacgaacg tgaaaaaaat
    71941 tagcttatta ctagccagtc tatgtgcctt gtttttagtg gcttgttcca atcaaaaaca
    72001 ggcagatggt aaactcaata tcgtgacaac cttttaccct gtctatgaat ttaccaagca
    72061 agtcgcagga gatacggcta atgtagaact cctaatcggt gctgggacag aacctcatga
    72121 atacgaacca tctgccaagg cagttgccaa aatccaagat gcagatacct tcgtttatga
    72181 aaatgaaaac atggaaacat gggtacctaa attgctagat accttggata agaaaaaagt
    72241 gaaaaccatc aaggcgacag gcgatatgtt gctcttgcca ggtggcgagg aagaagaggg
    72301 agaccatgac catggagaag aaggtcatca ccatgagttt gacccccatg tttggttatc
    72361 accagttcgt gccattaaac tagtagagca catccgcgac agcttgtcag cagattatcc
    72421 tgataaaaaa gagacctttg agaagaatgc agctgcctat atcgaaaaat tgcaagcctt
    72481 ggataaggct tacacagaag gcttgtctca agcaaaacaa aagagctttg tgactcaaca
    72541 cgcagccttt aactatcttg ccttggacta tggactcaaa caagtcgcaa tctcaggcct
    72601 ttctccagat gcagagccat cagctgctcg cttggcagaa ttgacagagt atgtcaagaa
    72661 aaataaaatc gcctatatct attttgaaga aaatgcctca caagcccttg ctaacacact
    72721 ttcaaaagaa gcaggtgtca aaactgatgt cctcaatcct ttagaaagtc tgacagaaga
    72781 ggacaccaag gctggagaaa actacatttc cgtgatggag aaaaacctca aggctttgaa
    72841 acaaacaaca gaccaagaag gcccagcaat cgaacctgaa aaggcagagg ataccaagac
    72901 agtccaaaat ggttacttcg aggatgcagc tgtcaaggac cgcaccttga gtgactatgc
    72961 aggtaactgg caatcagttt atcctttcct tgaagacggc acgtttgacc aagtctttga
    73021 ctacaaggct aagttgactg gtaagatgac ccaggctgag tacaaggctt actatacaaa
    73081 aggctatcag acagatgtga ctaagattaa cattactgat aatactatgg aatttgttca
    73141 aggtggacaa agcaagaaat acacttacaa gtatgtcggt aagaaaattt tgacttacaa
    73201 gaaaggcaat cgtggcgtgc gtttcctctt tgaagccaca gatgctgacg ctggacaatt
    73261 caaatatgtt cagtttagtg accacaatgt tgccccagtt aaggcagaac atttccatat
    73321 cttttttgga ggtacaagcc aagaagctct atttgaagaa atggataatt ggccaaccta
    73381 ctacccagat aacctatctg gccaagaaat cgcccaagaa atgttggcgc attgatgaga
    73441 aatcgactag ttcataagag ctagtcggtt ttttgatact agatggctaa cttcattata
    73501 gacctttcag aactaaggga acctgaaaaa ataaataaaa ctcttgaaat atctggactt
    73561 atatgctaga atgtagttag tgtataaggt tcattagaac accaaagccc ctaactagtg
    73621 ccatagttaa gggctttttt gacgtatctt agcgatttaa tgggtgttta taggctagtc
    73681 agtcggtcta cttcttacca tctagccatt tgcagacgaa atacaagata attccagcta
    73741 taacatctgc tataatagta agagcaagct ctggtataag gctcattagt ttcacctcct
    73801 ctcacgaacc cataggaacg taatcggtaa ccgatgacaa aagtattata tcacactaaa
    73861 tttagatcat caacctcact taatgcttga actattgtag attatatgct aaaatgtagt
    73921 taattgataa ggttcattag aacaccaaag cccctaacta tggccgtagt taagggcttt
    73981 tttgacgtat cttagcgatt taacgggtgt ttataggcta gtcactcggt ctacttctta
    74041 ctatctagcc atctgcagac gaaatacaag ataattccag ctataacatc cgctataata
    74101 gtaagagcga gctctatgat aaggctcatt agtttcacct cctctcacga acccatagga
    74161 acgtaatcgg taaccgatga caaaaatagt ataccacaat acatttagat catcaaggtc
    74221 acttaattct tgaaatatag ggtttaggcg acaaagtctt taaaatcaga aaaacgcata
    74281 atatcaggtg tgcaaaaact tgatactatg cgttttattg tgggaaggtt tactccattt
    74341 tctcctgaaa ttgagttttt gtccagcctc tgtttttagg gttgctgaga aaataatgtc
    74401 atgtggtgaa tatttgtaaa tcagtcagca gacagaacga atactcttcg aaaatctctt
    74461 cacatcatgt cagcttcgtc tttccgtata tatgtgactg acttcatcag ttctatctac
    74521 aacctcaaaa cagtgtttcg agctgacttt atcagttttc aaatctgtac tttgagcaag
    74581 ctgagactag cttcctattt gattttcatt gaatatcaga aacccattct ccatcaaata
    74641 attcgactgc gtctaataat ttttgatctg gcacggtgtc tgaaataaag gttgtgtatt
    74701 tggagagggg attaatttta aaaaatccag tcttgtaaaa tttagaacta tcaatcagta
    74761 agatggtttc atgggctttg tcaataatat tcttttttga aatagcttgg ctgagagaag
    74821 cttcataaac atattggtca tcaatacctc ttgctgaaca aaatgctaaa tcgatattaa
    74881 aatgatctaa taaagaattt tccttatcat agttgaccac ggaacaggat tgatgtttga
    74941 cctcgccaga tgtgataaag attttggagc tatctttaac agtttcagat agggtttgtg
    75001 cagtatgtaa accatttgta aaaataatca aattatcaag ttcagaaaga tagggacaaa
    75061 gttcgtagac agtagtactg gaatccagat aaacacacat accagaccga ataaagtctt
    75121 tagcgagact agcgattagt cttttttgcc tagtactttc tccttcccgt atttgatgag
    75181 aaagttcaat tgtgttcata gaggacaggg tcacgtatcc gtgctttctt ttgataagac
    75241 cttgattttc taagaaaatt aaatcacgac gtaaggtact tgtgctggag aaagtgattt
    75301 ctgccagctc ttttacggca attctttttt tctttttaat aatttcaatc aattcaagta
    75361 cacgttcatc ttttatcata agctcctcct aatttatcat ttcaactata ttatagcaca
    75421 aattggagga atttgaatta tttttatgaa tattgggtta acatttgaac attattcaag
    75481 taagcgttca catattgaaa aaataaaatg tggggattat aataaagtta atcaaggacg
    75541 aagagagaag aaaaatggaa gcggttttag caatagattt aggtgcgact tctggaagag
    75601 caatcgttgg ttacctttct gaaaataaac tagtaatgga agaaataaat cgcttttcta
    75661 atctacctat tagagtaaaa gggcatttat cttgggatat tgactttcta ctagctaaaa
    75721 ttcttgaaag tatccgcttg gctaatacta gttacaagat tttatctatc ggtattgaca
    75781 catggggagt tgattttgga ctgattgata atgaaggtaa gctgttatca caacctgttc
    75841 attatcgtga tgaaagaaca aagggagtgt taaaggaaat atctgaaatg actgaattag
    75901 aaaaactgta ttcagagaca ggaaatcaga ttatggagat aaataccttg tttcaactct
    75961 ttaaggcacg tcaagaatct cctgactctt tctataagac caataagatt cttttaatgc
    76021 cagatttgtt taattatctc ttgacaggta agtttgctac agaaaaaagc attgcttcaa
    76081 caactcaatt atttgatcct aggagtcaaa attggaatca gaatatctta aaactatttg
    76141 aattggattc atctttactt cctgaaattg tttcagaggg aaatgttctt ggaaggataa
    76201 aaaaggagta tggtttaggc gatattcctg ttgtgaatgt ttgtagtcat gatacagcaa
    76261 gtgcgattgt ctcagtacct aagacagaag gtagtttatt tatttcatca ggtacttggt
    76321 ctttggttgg agtggaactt acttcaccga ttcttactac cgaatccttc agttatggat
    76381 ttacaaatga agtcggtaaa gatggagaga ttacatttct gaagaattgt acagggttgt
    76441 ggatcataga ggaactaaga cgttcatttg aacgaagagg gaaagcctat tcttttgatg
    76501 atattaggac aatggtggag aaagaaaaag aaaatcttcc tctgattgat actgaatcaa
    76561 ctgaatttgc aacagaatct gatatgcaca agactttgac agaatatcta gcttatcatc
    76621 atgaaactag agagtggaca gatggacaac tatttaagat tgtttatgaa agcctagctg
    76681 aaacgtatag gaaagcgata gagttactag aagaactaac tcataaggtt tataagagga
    76741 tatatgtgat tggaggaggt gctagagcca gttactttaa ccaaatgatt gctgatagaa
    76801 ctggtaaaga ggttcttaca ggttcgactg agggtacagc tgtggggaat attgttgtgc
    76861 agctcatagc tatgggacaa ttaaaaggga tggaagaagc tcaccatgtt attgaggagt
    76921 ttctacaatt agagagttat tactcccaaa agaattaaaa agattgagag tttgtaaatt
    76981 tgcctccctc ccccttctta agttttgtac aagaaggggg gataattggt gaattgaaaa
    77041 atatttagtg ttttgatatg aggaggacaa gaatgtcaga tgtaaaacaa gaattaatta
    77101 agtatggcaa gaagctagta gaaacagatt tgacgaaagg aacaggtggg aatctcagtg
    77161 ttttcgatcg tgaaaaacaa ttgatggcaa ttaccccgtc gggtattgat ttctttgaaa
    77221 tcaaagaatc cgatattgta gtgatggata ttaatggaaa tgttgtagag ggagaacgct
    77281 tgccatctag cgaatggtat atgcatttga ttcaatatca aactcgtgat gatatcgatg
    77341 caattatcca tgctcataca acttatgcaa cagtattagc ttgtctcaga gaaccacttc
    77401 cggctagtca ttatatgatt gcagtggcag ggaaagatgt tcgggtagct gagtatgcaa
    77461 catatggtac gaaagaattg gctgtgaatg cagctaaagc aatggaaggt cgtagagcag
    77521 ttttactagc gaatcatgga attttagcag gtgcacaaaa tttattgaat gcatttaata
    77581 ttgttgaaga agttgaatat tgtgcaaaaa tttattgttt agctaagaat tttggagagc
    77641 cagtagttct tcctgatgag gagatggatt taatggcaga aaaatttaaa acatacggtc
    77701 agagaaaata gggaggatat taatgttaaa acatataccg aaaaatattt ctccagattt
    77761 attgaagact ttaatggaaa tgggacatgg agatgaaata gtattagctg acgcgaatta
    77821 tccttctgcc tcatgtgcaa ataagctaat tcgttgtgat ggcgtaaata ttccagaatt
    77881 attagattcc attctgtatt taatgccatt agatagttac gtcgatagtt caattcagtt
    77941 tatgaacgtt gtttcgggtg atgatattcc taagatatgg ggtacctata gacagatgat
    78001 tgaaggtcat ggtacagatc ttaaaacgat tacttatctt agaagagaag acttttatga
    78061 acgtagtaag aaagcttatg ctattgttgc tacaggagaa acttcacttt atgctaatat
    78121 tatccttaag aaaggagtag ttgttgaaag agaaaatgtt taatagagga attttagttg
    78181 ccagtcatgg taattttgct agcggagctc tcatgaccgc agaaatgttt gttggtgaga
    78241 caacaaatga tagagttagg acattaggtt tgatgcctgg agagaatatt gtagagtttg
    78301 aacattattt taaaaatcaa gtaaatgaac tgttagactc aaatcaagag gttatcgttt
    78361 tgactgactt gattggagga agtcctaata atgtggcttt gtcacggttt ttaaatttgg
    78421 attcagttga tattgtaaca gggtttaata tccctctcct agtggaatta atatcaagtt
    78481 atgattcaaa aatcaattta gaagaaattg ttcaaaatgc tcaaaatagt ttgtttaatg
    78541 ttaaacaaca acttaacgta gaggaggaag aggatttatg tctatagagt ttgttcgtat
    78601 tgatgaccgt ctggtacatg gtcaagttgt cactacgtgg ctaaaaaagt atgatattga
    78661 gcaagttatc attgttaatg atcgcatctc agaagataaa acacgacaat ctattttaaa
    78721 gatttctgca ccggtaggtt taaaaattgt tttctttagt gtaaaacggt ttgtggaagt
    78781 tttaaactct gtgccaataa aaaagagaac aatgctgata tatacaaatc caaaagatgt
    78841 gtatgattct attgaaggaa atttaaaatt ggagtacctc aatgtaggac agatgagtaa
    78901 aacggaggaa aatgaaaagg taacgggagg tgtagctcta ggtgaagaag acaaatatta
    78961 ttttaagaaa atagttgata agggaacgag agttgaaatt caaatggttc ctaatgataa
    79021 agttacaatg ttggaaaaat ttttataaaa ataatttaag gaggtacagt atatgctatt
    79081 cacacaagca ttactggtga cattagttgg gattattgcc actattgact ataatggacc
    79141 gttatttatg attcaccgtc cgttagttac aagtgcaatg gttggcttag tcttaggaga
    79201 tttcacccaa ggtgttctta ttggttcagc tcttgaatta acttggctcg gtgtaacagg
    79261 tattggaggt tacactccac cagatactat ttcaggtgcg attattggta ctgcatttgg
    79321 tattttgtct ggtcaaggag aaactgctgg tatcgctata gcagttccaa ttgcagttgc
    79381 tactcaacag ttggatgttc ttgcaaaaac tttagatgtt tattttgtga aaaaagctga
    79441 taatgatgct aaaaacggag attattcaaa gatcggtttt tatcattatt caagtttggt
    79501 tttaatcact ttatttaaaa ttgtaccaat tttcctagct attatgcttg gaggggaata
    79561 tgtggcagac ttgtttgcta aggttccacc aatcgttatg cagggactta actctgcagg
    79621 tgctttacta ccttcaattg gttttggtat gcttttaaat atgatgctca agaaaaatat
    79681 gtgggtattc ttgttgattg gattcatttg ttctgtgtat ggaggaatgt caaccattgg
    79741 gatctcacta gttggtattg cggtagcata cttctacgat atgattggaa gtaaaccaca
    79801 agaaacaact tcaagtagtg atgttgagga ggatcttgat ctatgatgaa taataaagta
    79861 actaaagttg aacttaaaaa agttttcaaa cgaagtttta tgtatggttc ttcatggaac
    79921 tatgagagaa tgcagaacct aggttttcta tatacaattc ttccagtatt gaaaaaacta
    79981 tacccagaca aagattcagc ttctcctgca atgaaacgtc accttgagtt tttcaatact
    80041 catcaaacag cggcaccatt tattcttgga gttacttccg ctatggaaga acaagaagga
    80101 aatgaaggtg cagcttcaat tactggtatt aaagttggct tgatggggcc actggctggt
    80161 ctaggagata gtttgttctg gctgacacta gttcctatct gttttagtat tggtgcgtct
    80221 tattctaaag acggcggtgc tttaggtatc tttatcgcct taatattgtt taatattatt
    80281 aatattcctg ttaaatattt cggtttgaaa tatgggtata ctaagggttc tagtcttatc
    80341 caagaaaata atacaaaagg aacattgaat cgcgttacga gtatggcgac agcattaggg
    80401 ctagtactag tgggtggttt gattccatca atggttggta ttaattttgg attagaattt
    80461 aagcaggggg aacttgttat ttctgttcaa gaaatgatta caaaattaat tccaggattt
    80521 atccctatgg ctttgacttt attaatgtgt aaattaatta gaaaaggaaa gaatccggtt
    80581 gtactaatct ttagtgttat ggctattgga gttatcctag ttgttttagg aattttgaag
    80641 tagtagaaag tgtggaggtg gtatttggga tatcacctcc attttggaag agaggtaaag
    80701 agtgaaatta tggtataaga aagctgccgc aaattggaat gaagccttgc cgattgggaa
    80761 cggtcattta ggtggtatga tttatggttc agctacaaaa gaatgtattc aactaaacga
    80821 tgagactatt tggtatagag gaaagtcaga tagaaataat ccagactcac tattgcatct
    80881 taaaaaaatt cgggaatatc ttttagatgg agaaattcag aaagccgaag aattgataaa
    80941 gttaacaatg tttgctaccc caagagatca aagccactat gaattacttg gggaactttg
    81001 cattgagcat atagatattc agtcttgtgc tctttcattg tatgaaagag agctagattt
    81061 agatacagct atttctaatg ttgtgtttga gcctaatagt tgtaatttac aaataaaaag
    81121 agaatatttt acgagtttta ataagaatat tttatgttgc cgtatagtgt catcagttca
    81181 aaacacatta aatttaaaca ttaatttggg tagaaataaa cggtttaatg acgaagtatc
    81241 taaactggat tcaagtacaa ttttaatgtc ggcctctgct ggaggtagaa aaggtgttca
    81301 gtttaaagta gtatgtcatt ctaaggttac ggatggtgaa gtaagtgtat tgggagagac
    81361 aatagttatt cggaatgcta cagaggtatt tctttatctc aaatcaatga cggattattg
    81421 gggaaatata gatatttctt ctcttcaggg agaatttagt agtattgatt actttacaga
    81481 aaaagatgaa catgtaaaaa aatatcagga gcaatttaat agagttgatt ttaaactaga
    81541 ctatagtaaa ggttgtctta gcattccaac gaatctactt cttgaaaaca ctaaaaagta
    81601 tagtaactac ttgactaact tgttatttca ttatggaaga tatctgttaa tatcgtctag
    81661 tcaaccgaat ggtttacctg ccaatcttca aggaatatgg tgtgatgaat taaatccaat
    81721 ttggggttct aaatatacga ttaatattaa tactcaaatg aattattgga tggtaggtcc
    81781 atgtgattta ccagaagtag aatatccatt atttgatatg ctcgaaagaa tgagagaacc
    81841 gggaagacta accgctaaga aaatgtatgg agctagaggt tttacagcac atcataatac
    81901 ggatggtttt ggcgatacgg ctccccaatc tcatgccatg ggggctgcaa tttgggtatt
    81961 aactattcca tggttatgta ctcatatttg ggaacactat ttatatttcc aagatgagcg
    82021 tattcttacg gaacattttg aaatgataaa agaagcattt cttttctttg aagattattt
    82081 atttgaggtg gatggctact tgatgacagg tccaagtgtc tcaccggaaa ataaatatcg
    82141 cttaaaaaat ggtattgaag gaaatgcttg tctatcatct acaattgata atcaaattct
    82201 aagatatttt tgtgattcat gcattggcat tgcaaaacaa ttaggagaca attcggattt
    82261 tattagtcgt gtgaaggagt taaaaaagaa attacctaga acaaaaatag gtagtaatgg
    82321 gcaaatacaa gaatggctag aggattatga agaagtagag cctggtcata gacacatttc
    82381 acctctattt gggctttatc cttataatga gattgatatt cataaaactc cggaattagc
    82441 agaagcagct aaaatcacta tcaataggag attatcaaac gctaactttt tatcttcaca
    82501 ggatagggag caagcgatta ataattggtt agtaagtggt ttgcatgcta gtacacaaac
    82561 aggttggagt gctgcatggc tgattcattt ttttgcgaga ctatatcaag gtgaacctgc
    82621 ttataaccag attaatggtt tgttaaataa tgcgactctt ggcaatttat ttcttgacca
    82681 tccaccattt caaattgatg gtaatttagg tttggtgagt ggaatttgtg aattattagt
    82741 acagagccat cataattggt tatcactaat tccagcttta ccttctgctt ggtcagaagg
    82801 agaagtgaaa ggtttcagag taagaggagg atataaggta tcgtttgctt ggaaaaatgg
    82861 ggatataaca ttcctaaaat tggaaggagg aaacaaagat caaaaagtaa gagtaagaat
    82921 atatggcaaa aatactgatg tacaaaatat tgaattggta tttaattcag aaaaaattat
    82981 tgagttaaat ttttaggtat aagtcatgaa taaagaaaaa ataaaaagaa aattaatcac
    83041 aatattgttt gtatgtattg ggatgttatg ttttggattg ttagcaggag ttaaggctga
    83101 taatcgtgtt caaatgagaa cgacgattaa taatgaatcg ccattgttgc tttctccgtt
    83161 gtatggcaat gataatggta acggattatg gtgggggaac acattgaagg gagcatggga
    83221 agctattcct gaagatgtaa agccatatgc agcgattgaa cttcatcctg caaaagtctg
    83281 taaaccaaca agttgtattc cacgagatac gaaagaattg agagaatggt atgtcaagat
    83341 gttggaggaa gctcaaagtc taaacattcc agttttcttg gttattatgt cggctggaga
    83401 gcgtaataca gttcctccag agtggttaga tgaacaattc caaaagtata gtgtgttaaa
    83461 aggtgtttta aatattgaga attattggat ttacaataac cagttagctc cgcatagtgc
    83521 taaatatttg gaagtttgtg ccaaatatgg agcgcatttt atctggcatg atcatgaaaa
    83581 atggttctgg gaaactatta tgaatgatcc gacattcttt gaagcgagtc aaaaatatca
    83641 taaaaatttg gtgttggcaa ctaaaaatac gccaataaga gatgatgcgg gtacagattc
    83701 tatcgttagt ggattttggt tgagtggctt atgtgataac tggggctcat caacagatac
    83761 atggaaatgg tgggaaaaac attatacaaa cacatttgaa actggaagag ctagggatat
    83821 gagatcctat gcatcggaac cagaatcaat gattgctatg gaaatgatga atgtatatac
    83881 tgggggaggc acagtttata attttgaatg tgccgcgtat acatttatga caaatgatgt
    83941 accaactcca gcatttacta aaggtattat tcctttcttt agacatgcta tacaaaatcc
    84001 agctccaagt aaggaagaag ttgtaaatag aacaaaagct gtattttgga atggagaagg
    84061 taggattagt tcattaaacg gattttatca aggactttat tcgaatgatg aaacaatgcc
    84121 tttatataat aatgggagat atcatattct tcctgtaata catgagaaaa ttgataagga
    84181 aaagatttca tctatattcc ctaatgcaaa aattttgact aaaaatagtg aggaattgtc
    84241 tagtaaagtc aactatttaa actcgcttta tccaaaactt tatgaaggag atgggtatgc
    84301 tcagcgtgta ggtaattcct ggtatattta taatagtaat gctaatatca ataaaaatca
    84361 gcaagtaatg ttgcctatgt atactaataa tacaaagtcg ttatcgttag atttgacgcc
    84421 acatacttac gctgttgtta aagaaaatcc aaataattta catattttat tgaacaatta
    84481 caggacagat aagacagcta tgtgggcatt atcaggaaat tttgatgcat caaaaagttg
    84541 gaagaaagaa gaattagagt tagcgaactg gataagcaaa aattattcca tcaatcctgt
    84601 agataatgac tttaggacaa caacacttac attaaaaggg catactggtc ataaacctca
    84661 gataaatata agtggcgata aaaatcatta tacttataca gaaaattggg atgagaatac
    84721 ccatgtttat accattacgg ttaatcataa tggaatggta gagatgtcta taaatactga
    84781 agggacaggc ccagtccctt ttccaacacc agataaattt aatgatggta atttgaatat
    84841 agcatatgca aaaccaacaa cacaaagttc tgtagattac aatggagacc ctaatagagc
    84901 tgtggatggt aacagaaatg gtaattttaa ctctggttcg gtaacacaca ctagggcaga
    84961 taatccctct tggtgggaag tcgatttgaa aaaaatggat aaagttgggc ttgttaaaat
    85021 ttataatcgc acagatgctg agactcaacg tctatctaat tttgatgtga ttctatatga
    85081 caataataga aacgaagttg ctaagaaaca tgttaataat ttgtcgggtg aatctgttag
    85141 tctagatttc aaagaaaaag gagcaaggta tattaaagtt aaattactaa cgagtggagt
    85201 gcctttgagt ttagcagaag tagaggtttt tagagaatca gatggtaagc aatctgaaga
    85261 ggatatagat aaaataacag aagataaagt agtctctaca aataaggtag ctactcaaag
    85321 ttcaaccaat tatgagggtg tagctgcttt agcagttgat ggtaataaag atggagatta
    85381 cggacatcat tcggtgactc atactaaggc agattctaac gcttggtggc aggtcgatct
    85441 gggagaagag tttacggttt ctaaagttga tatttataat agaacagatg ccgaacctca
    85501 gcgtttatct aattttgatg ttatttttct atcttcatca ggagaagaag tttttagaag
    85561 acattttgat aaagtagttg atggtttgtt atctttaaaa gtaccttctg taggggctaa
    85621 gctagtcaaa atagaattaa aatcagcagc tattccgtta agtttagcgg aagttgaagt
    85681 ctatggttca aagagaactc cgaagaaact ttctaatatt gcattaacca aagaaactcg
    85741 acagagttca acggattaca atggtttttc tcgtctagca gttgatggaa ataaaaacgg
    85801 agattatggt catcattcag tgactcatac caaaggagat tctccttcat ggtgggagat
    85861 agatttagca caaaccgaag aattagaaaa gttaattatt tataatagaa cagatgctga
    85921 aattcagaga ttatcaaatt ttgatattat tatatatgat tcaaataatc atgaagtttt
    85981 taaacaacat attgacagtt tagaaagcaa taatctatcc atagacttaa aagggctgaa
    86041 gggaaaaaag gttagaattt ctttgagaaa cgcaggaatt cctttaagtt tggcagaggt
    86101 agaggtttat acttataagt aattttaaaa attatcatcg gtagtatgaa agaaacagaa
    86161 aaataagagg aaaatagtat gattcaacat ccacgtattg gtattcgtcc gactattgat
    86221 ggtcgtcgtc aaggtgtacg cgaatcactt gaagtacaaa caatgaacat ggctaaaagt
    86281 gtggcagatt tgatttcaag cacattgaaa tatccagatg gggaacctgt ggaatgtgtg
    86341 atttctccat ctaccattgg tcgtgttcca gaggctgcag cttcccatga gttgtttaaa
    86401 aaatcaaatg tttgcgcaac aattacagtt acaccatgct ggtgttatgg tagtgaaact
    86461 atggatatgt ctccagatat tcctcatgct atttggggat ttaatgggac agaacgccca
    86521 ggagctgtct atcttgcagc tgtactagct tcacatgctc aaaaagggat tccagccttt
    86581 gggatttatg gtagagatgt tcaggaagct aatgatacag atattccaga agatgtcaaa
    86641 gaaaaacttt tacgttatgc gcgtgcagct cttgcaactg gcttgatgag agacactgct
    86701 tacctatcaa tgggtagtgt ttcgatgggg attggtggtt ctattgtaaa tccggatttc
    86761 ttccaagaat acttaggaat gcgaaatgaa tcggtagata tgacggagtt cacacgccgt
    86821 atggaccgtg gtatttacga ccctgaagag tttgaacgtg ctatggtttg ggtaaaagaa
    86881 catatcaaag aaggagttga ccgaaatcgt gaggatttga ttctttctaa agaagagaaa
    86941 gaaaaacaat gggaatttgt tattaagatg ttcatgattg gacgtgactt aatggttggt
    87001 aacccaagac ttgctgaact tggttttgag gaagaagcag ttggtcacca tgctttagta
    87061 gctggtttcc aaggtcaacg tcagtggaca gaccattttc caaatggaga ttttatggaa
    87121 actttcctca atactcagtt tgactggaat ggtattcgaa aaccatttgt atttgcgaca
    87181 gagaatgatt cactaaatgg tgtgtctatg ctctttaatt atctactaac aaatactcca
    87241 caaatctttg ctgatgtgcg tacttattgg agtccagagg ctgttgaacg tgtaacagga
    87301 tatactttag agggtcgtgc tgcagctggc ttcttacatc taatcaactc tggttcttgt
    87361 acattggatg gtacaggtca agctactcga gatggcaaac ctgttatgaa accattctgg
    87421 gagttggatg aaagtgaagt acaggctatg cttgaaaata cagacttccc accagcaaac
    87481 cgcgagtact tccgtggagg aggattctca actcgtttct tgacgaaggg ggatatgcca
    87541 gtaacaatgg tacgtctcaa tcttctaaaa ggggttggtc cagtgctaca aattgcagaa
    87601 ggttacacac ttgaacttcc tgaagatgtt caccatactt tagataatcg tacagattca
    87661 ggatggccaa ctacttggtt tgctccacgt ttgacaggaa aaggtgcttt caagtctgtc
    87721 tatgacgtca tgaataattg gggagctaat cacggagcca taacatatgg acacattgga
    87781 gcagacttga ttaccttggc ttctatgttg agaattcctg tcaatatgca taatgtacct
    87841 gaggaagata tctttagacc taaaaattgg tccttatttg gaacagaaga tctagaatca
    87901 gcagactatc gtgcatgtca gttgttggga ccactacata aataaaactt gtttatatag
    87961 gaggtgaact tacgtccctc ctatcctttt aaaaagattt gttaaacaat tcacaaataa
    88021 ttgaaaacga atacaaaaag taatataatg atgttaaata gatagcgcgg aggcgcagga
    88081 ggaaaattat atggctatat tttatgttcc ggcagtcaac cttattggaa aaggtgttgt
    88141 aaatgaagtg ggtccttata tcaaggaact tggctataaa aaggcacttt tggtgacaga
    88201 taagtacatc gaaggcagtg atattttacc taagacttta aaaccactgg atacagaagg
    88261 aatcgaatat gtcatcttta gcgatgtaga gccaaaccct acttgtaaaa atgtcacaga
    88321 tggggtagct gctttgcaag aacatggctg tgactttatc atcagtcttg gcgggggttc
    88381 tccacaggat gcagctagtt gtatttctat catggctaca aatggtggaa aaccacagga
    88441 ttatgaaggg cttcataagt ctgctaaaaa aggtttgcca gttgtggcta tcaatacaac
    88501 ggcaggtaca tcagcagaaa ttaccattaa ctatgtgatt actgatgaag aacgcaaggt
    88561 taagatggta atggttgaca agaatagcct tgccttgatt tctgtcaatg accctgaact
    88621 catgctttcc aaacctaaag gcctgactgc tgctactggt atggatgctc tgactcatgc
    88681 tgttgaagct ttggtaacac ctggtactta tgatgtaacc aagaaactgt ctattggtgc
    88741 tattgagctt atcaaggaat atcttcctcg tgctgtagaa aatggacatg atattgaagc
    88801 gcgtgaaggt atggtcaatg ccatcttcct tggtggtatg agctttaata atgctggtct
    88861 tggctatgtt cactcaatgg ctcaccaact cggtgcagta tataatttgc cacatggcgt
    88921 gtgctgtgcc atgttgctac cagttataga acgtgaaaat gctaaacgtg taccagaagc
    88981 tttccgcaat gttgccaaag ccttgggact tcatgtagaa ggtaaatcag atcaagaatg
    89041 tgccgattat gcgattgctg agattgagaa gctttctgag acagtaggta ttcctaagaa
    89101 actgactgaa cttggtattg aagaaaaaga tttcgacttt gaataccttt ctaagaatgc
    89161 cttgattgat gcctgcgcac caggaaatcc atttatgcca accttagaag aaacgattgc
    89221 cttttataaa gagttatttt agcaagagat tggacgacaa taggacaatt cacctctaat
    89281 tattgacatt tcaggaaaaa tcgcagtaaa aacggcacag ccttctttaa atgtgctata
    89341 atactagaaa aatacttgtg gaggttccat tatggcaata tttttcatga tttttctgat
    89401 tgtttgtgtg ctcctattgg tgatagtcac actgagtaca gtttatgtgg ttcgtcagca
    89461 gtcggtggcg attattgaac gctttgggaa ataccaaaag gttgctaata gcggtattca
    89521 tattcgcttg ccttttggga ttgactcgat tgcagcacgg attcagttgc gcttgttgca
    89581 aagtgatatt gtggttgaga ctaagaccaa ggacaatgtg ttcgttatga tgaatgtagc
    89641 gactcagtac cgtgtcaacg agcagagcgt gacagatgct tactataaac tcatacgtcc
    89701 agaatctcag attaaatctt atatcgaaga tgctcttcgc tcttctgttc caaaattaac
    89761 cttggatgaa ttgtttgaga aaaaagatga gattgccctt gaggttcaac accaagtagc
    89821 agaagaaatg accacttacg gctacattat cgtgaaaacc ttgattacca aggtcgaacc
    89881 agatgcagaa gttaagcaat ctatgaatga aatcaatgcg gcgcaacgta agcgggtcgc
    89941 agcacaagaa ttggcggaag ctgacaagat taaaattgtc actgcagctg aagccgaagc
    90001 agaaaaagac cgccttcatg gtgtggggat tgcccaacaa cgtaaggcga ttgtggatgg
    90061 attggcagag tctatcaccg aactcaagga agccaatgtt ggcatgacag aagaacaaat
    90121 catgtctatc ctcttgacca accagtattt ggataccttg aatacctttg cctctaaagg
    90181 aaatcaaacc atctttttac caaatactcc aaatggtgtg gatgatatcc gtacacaaat
    90241 cttgtcagcc cttcgcgctg agaagaaata atagactaat actcttcgaa aatctcttca
    90301 aactacgtca gcgtcgtctt gccgtataga tgttactgac ttcgtcagtt ctatctgcaa
    90361 cctcaaaaca gtgttttgag ctgacttcgt cagtcttatc tactacctca aaacggtgtt
    90421 ttgagcaacc tgtagctagt ttcctagttt gctctttgat tttcattgag tataaagagc
    90481 ttggcaacag gctctttttg tattgcgttt attaagaaaa acaaaaaaca tcgatataca
    90541 tttaactaaa aattattgta tgttatctcc cttaattagg aatgataagg gaataactag
    90601 aaagatttgt gaatacaaac tatttctgat atacaaaata tacagtaata atgaatgatg
    90661 ggagatggga tgaaagaatt tcaatttgag agaaagcagc gtttttcttt gaggaaatat
    90721 gcaataggag cttgttcggt cttgctagga acgagtttat tttttgctgg tatgggtgct
    90781 cagcctgtac aggatacaga aacgagttca gcactaattt caagtcatta tttggatgag
    90841 caggatttat ctgaaaagct gaaatctgag ttgcaatggt ttgaattaga aaacaagctt
    90901 ttgaacttat gggagcatta ggttactatg aaggatttgt tccttatgtt tcaaatcaat
    90961 accaaaacca agctgaagaa gaatacaaac cgctatctga taaatatatt ttcgaaaaaa
    91021 tcttaggaaa aacatatgca gccttcaaaa aagatcaaat taatgagcgt gtcgagaaat
    91081 taggtaagtt aaaacctatt acaataaatt acaacggaaa atcagaagta attgatagta
    91141 aagaaaaatt acaagagctt atgaataaag ccgttaaaga cgaagtggct caaatatagt
    91201 aaaatgaaat aagaacagga caaatcgatc aggacagtca aatcgatttc taaaaatgtt
    91261 ttagaagtag aggtgtacta ttctagtttc aatatactat aaaatcaggc aataccacgg
    91321 ctaaaaagtt tgagtttatc gaaataccag tgcaaaaact gaaaaaagca atttataaag
    91381 ctcatctcaa agattcagat
//
LOCUS       DAVLBE010000002        79420 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.002, whole genome shotgun sequence.
ACCESSION   DAVLBE010000002 DAVLBE010000000
VERSION     DAVLBE010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 79420)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 79420)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..79420
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.002"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            157..945
                     /gene="codY"
                     /locus_tag="VXB91_000091"
     CDS             157..945
                     /gene="codY"
                     /locus_tag="VXB91_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HEV0469611.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            945..1520
                     /locus_tag="VXB91_000092"
     CDS             945..1520
                     /locus_tag="VXB91_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEV0469612.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDCFHPESKLFPPHNLIGTSGRNLYGDLGIFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELSE"
     gene            1602..1687
                     /locus_tag="VXB91_000093"
     tRNA            1602..1687
                     /locus_tag="VXB91_000093"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1636..1638,aa:Leu,seq:aag)
     gene            1970..3100
                     /gene="ugpC"
                     /locus_tag="VXB91_000094"
     CDS             1970..3100
                     /gene="ugpC"
                     /locus_tag="VXB91_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HEV0469613.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFINVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            3601..4359
                     /locus_tag="VXB91_000095"
     CDS             3601..4359
                     /locus_tag="VXB91_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEV0469614.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGFSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAVDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKALTGEMTLMKLSGMIYDEGLLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            4447..4959
                     /locus_tag="VXB91_000096"
     CDS             4447..4959
                     /locus_tag="VXB91_000096"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HEV0469615.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            5141..6085
                     /locus_tag="VXB91_000097"
     CDS             5141..6085
                     /locus_tag="VXB91_000097"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HEV0469616.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYGYL"
     gene            6094..6771
                     /locus_tag="VXB91_000098"
     CDS             6094..6771
                     /locus_tag="VXB91_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HEV0469617.1"
                     /translation="MTYLDAFKSGTLVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEMSPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELLFDASLALERL
                     DDLFGAVHSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLTKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFRN
                     AMDLWKD"
     gene            6869..7627
                     /locus_tag="VXB91_000099"
     CDS             6869..7627
                     /locus_tag="VXB91_000099"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HEV0469618.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            7665..9170
                     /gene="lytC"
                     /locus_tag="VXB91_000100"
     CDS             7665..9170
                     /gene="lytC"
                     /locus_tag="VXB91_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
                     /protein_id="HEV0469619.1"
                     /translation="MSVTFFIGEQRLKTKIGLASICLLGLATSHVAANETEVAKTSQD
                     TTTASSSSEQNQSSNKTQTSAEVQTNAAAHWDGDYYVKDDGSKAQSEWIFDNYYKAWF
                     YINSDGRYSQNEWHGNYYLKSGGYMAQNEWIYDSNYKSWFYLKSDGAYAHQEWQLIGN
                     KWYYFKKWGYMAKSQWQGSYFLNGQGAMMQNEWLYDPAYSAYFYLKSDGTYANQEWQK
                     VGGKWYYFKKWGYMARNEWQGNYYLTGSGAMATDEVIMDGARYIFAASGELKEKKDLN
                     VGWVHRDGKRYFFNNREEQVGTEHAKKIIDISEHNGRINDWKKVIDENEVDGVIVRLG
                     YSGKEDKELAHNIKELNRLGIPYGVYLYTYAENETDAENDAKQTIELIKKYNMNLSYP
                     IYYDVENWEYVNKSKRAPSDTDTWVKIINKYMDTMKQAGYQNVYVYSYRSLLQTRLKH
                     PDILKHVNWVAAYTNALEWENPYYSGEKGWQYTSSEYMKGIQGRVDVSVWY"
     gene            9668..10186
                     /locus_tag="VXB91_000101"
     CDS             9668..10186
                     /locus_tag="VXB91_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HEV0469620.1"
                     /translation="MVELKKEAAKDVATLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGHLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEAGEYRNVEESLERVLAIYRYLITLFQKALDVTDEEGDDVTNDIFVGAKAELEKTVW
                     MLAAELGQAPGL"
     gene            10316..10822
                     /locus_tag="VXB91_000102"
     CDS             10316..10822
                     /locus_tag="VXB91_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEV0469621.1"
                     /translation="MTKKIVAIWAQDEEGVIGKDNRLPWHLPAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNPEKKIDGVATFQDVQSVLDWYQAQEKNLYIIGG
                     KQIFQAFEAYLDEVIVTHIHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTI
                     QYRKRKEV"
     gene            10822..10992
                     /locus_tag="VXB91_000103"
     CDS             10822..10992
                     /locus_tag="VXB91_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0469622.1"
                     /translation="MERSLFGLFTAFLCFICFLAGAQAFRKKRYGLSILLWLNAFTNL
                     VNSIHAFYMTLF"
     gene            11024..12256
                     /gene="clpX"
                     /locus_tag="VXB91_000104"
     CDS             11024..12256
                     /gene="clpX"
                     /locus_tag="VXB91_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HEV0469623.1"
                     /translation="MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DENSSYMQEIIDEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            12265..12852
                     /locus_tag="VXB91_000105"
     CDS             12265..12852
                     /locus_tag="VXB91_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HEV0469624.1"
                     /translation="MELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHAPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            12863..13243
                     /locus_tag="VXB91_000106"
     CDS             12863..13243
                     /locus_tag="VXB91_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HEV0469625.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            13295..14185
                     /gene="rapZ"
                     /locus_tag="VXB91_000107"
     CDS             13295..14185
                     /gene="rapZ"
                     /locus_tag="VXB91_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HEV0469626.1"
                     /translation="MTKKQLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKRLVQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            14182..15159
                     /locus_tag="VXB91_000108"
     CDS             14182..15159
                     /locus_tag="VXB91_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HEV0469627.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDLRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVAGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQTILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQEYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            15156..16067
                     /gene="whiA"
                     /locus_tag="VXB91_000109"
     CDS             15156..16067
                     /gene="whiA"
                     /locus_tag="VXB91_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HEV0469628.1"
                     /translation="MSFTVAVKEEILGQHHLSRHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(16101..17069)
                     /locus_tag="VXB91_000110"
     CDS             complement(16101..17069)
                     /locus_tag="VXB91_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEV0469629.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEEFAITTS
                     KGSHLTKTVIIAMGGGAFKPRPLELEGVEDYENIHYHVSNIQQYAGKKVTILGGGDSA
                     VDWALAFEKIAPTTLVHRRDNFRALEHSVQTLQESSVTIKTPFAPSQLLGNGKTLDKL
                     EITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYA
                     IGDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            17205..18062
                     /locus_tag="VXB91_000111"
     CDS             17205..18062
                     /locus_tag="VXB91_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HEV0469630.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYMSTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERL
                     LGGWKHEKK"
     gene            18049..18828
                     /locus_tag="VXB91_000112"
     CDS             18049..18828
                     /locus_tag="VXB91_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HEV0469631.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            18852..20204
                     /locus_tag="VXB91_000113"
     CDS             18852..20204
                     /locus_tag="VXB91_000113"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HEV0469632.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAVQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVDYYVDTITDVVRAEIGID
                     "
     gene            20278..20652
                     /locus_tag="VXB91_000114"
     CDS             20278..20652
                     /locus_tag="VXB91_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HEV0469633.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPNELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            20654..21502
                     /locus_tag="VXB91_000115"
     CDS             20654..21502
                     /locus_tag="VXB91_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEV0469634.1"
                     /translation="MKLAVFTDSSAYLSAEILQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASELPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGVIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGAGSIAL
                     GYIPVI"
     gene            21779..22546
                     /locus_tag="VXB91_000116"
     CDS             21779..22546
                     /locus_tag="VXB91_000116"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HEV0469635.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLTDPDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLAGFEADVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEVRESIQQGAADEEELIAGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            22558..23742
                     /locus_tag="VXB91_000117"
     CDS             22558..23742
                     /locus_tag="VXB91_000117"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HEV0469636.1"
                     /translation="MPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHSPIHDVDIA
                     TSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSAVSFVR
                     SLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDALRIMR
                     GFRFQASLGFALEPETFKAMKTLTPLLEKISVERTFVEFDKLLLAPFWRRGLASMIES
                     QAYDYLPDMASSQDKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSFLKSWKTSR
                     QFAKQVQDLLIILALRENGELSKRDCYRFDLDLLLQAENLRQAQGKEVNPQVIKETYQ
                     SLTIHDKKEIQINGGILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIHAYLRE
                     KK"
     gene            23739..25610
                     /locus_tag="VXB91_000118"
     CDS             23739..25610
                     /locus_tag="VXB91_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV0469637.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTVLSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELERAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELAWMRRQPQAR
                     ATKQQARINRFHDLKKEVSGSSAETDLTMNFETSRIGKKVIEFQDVSFAYENKPILQN
                     FNLLVQAQDRIGIVGDNGVGKSTLLNLIAGSLEPTAGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDGKIRPFFGHYTDYLDEKAFETDMANQVQKAEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIETLEKRIAAIEEEMQANGSDFGKLATLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(25753..26937)
                     /gene="mntE"
                     /locus_tag="VXB91_000119"
     CDS             complement(25753..26937)
                     /gene="mntE"
                     /locus_tag="VXB91_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HEV0469638.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLAAGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLEERF
                     GVFDTDVHIEPAPIPEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            27241..29937
                     /locus_tag="VXB91_000120"
     CDS             27241..29937
                     /locus_tag="VXB91_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEV0469639.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLAEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LIEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILVIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVVLANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEGHVLTGAELNELSDEEFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            29950..30741
                     /gene="yghU"
                     /locus_tag="VXB91_000121"
     CDS             29950..30741
                     /gene="yghU"
                     /locus_tag="VXB91_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HEV0469640.1"
                     /translation="MSAYQLPTVWQDEASNQGAFTGLNRPTAGARFEQNLPKGEQAFQ
                     LYSLRTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPAL
                     LDQSGTEDVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQAGAAPFLGGGFG
                     HFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QGNLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK"
     gene            30857..31267
                     /locus_tag="VXB91_000122"
     CDS             30857..31267
                     /locus_tag="VXB91_000122"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEV0469641.1"
                     /translation="MEKKIVKDILFLSQVSQPASQEDLYLARDLQDTLLANRDTCVGL
                     AANMIGVQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETIRL
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            31279..32874
                     /locus_tag="VXB91_000123"
     CDS             31279..32874
                     /locus_tag="VXB91_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0469642.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPKSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRIYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTK
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESIKGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGRTFEGQVGKDSYLKTFKVQ"
     gene            33053..33217
                     /locus_tag="VXB91_000124"
     CDS             33053..33217
                     /locus_tag="VXB91_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HEV0469643.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKENKDKFLSILTSLAGLALV
                     LVAVWLGWPK"
     gene            33296..34024
                     /gene="yaaA"
                     /locus_tag="VXB91_000125"
     CDS             33296..34024
                     /gene="yaaA"
                     /locus_tag="VXB91_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HEV0469644.1"
                     /translation="MKILIPTAKEMNTDLPSIETTLLRSESQAVLDALALYSASQLES
                     FYKVSAEKAAEECQNIQALKRQTVQHYPALKLFDGLMYRHIKRDKLTEVEQAYLENHV
                     FITSALYGVVPALSPMAPHRLDFLMKLKVAGKTLKSHWKAAYDEAVKQEEVIFSLLSS
                     EFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
     gene            complement(34075..35559)
                     /locus_tag="VXB91_000126"
     CDS             complement(34075..35559)
                     /locus_tag="VXB91_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003096885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0469645.1"
                     /translation="MRNLLSTKVQRQLRLMETLIQNRNWMKLHELAEKLGCTERILKS
                     DLNELRIAFPSINIQSSVNGIMIDLEVNTSVEDIYQYFLANSQSFQLLEYMFFNEGLP
                     IYRTIENLYFSSANLYRLGRNITKVLSSQFQIELSFTPSEIRGNEIDIRYFFAQYFSE
                     RYYFLDWPFPDLPEEDLTEFADFFYKITNYPMRFSIYRMYKLMIAISIHRVKNGHFID
                     LPNHFYKEYYPLLKSIPNFQETLAYFSKHFGLEMTPDTIAQIFISFLQNDIFLDPQEF
                     FNSLEDNSQARYSYQLLSQILERLSKQYKITFTNHDELIWHLHNTAFFERQEIFSTPI
                     LFEQKALTIKKFEVYFPDFMGSARQELAQYRQAIGQHDHPEQLEHLMYTILTHAENLS
                     TQLLENRPPIKVLIISNFDHAISLTFVDMLSYYCNNRFTFDIWDELKTSPEILNQTDY
                     DIIVSNFYISGITKKFICRNHLSIMNLVNHLNTLSNEIHLSNTL"
     gene            35775..41099
                     /locus_tag="VXB91_000127"
     CDS             35775..41099
                     /locus_tag="VXB91_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK signal domain/LPXTG anchor domain surface
                     protein"
                     /protein_id="HEV0469646.1"
                     /translation="MKHSHKKSFDWYSMQQRYSIRKYYFGAVSVLLGTALVLGAAASV
                     QTVQAEENKQETTNSISVGRGEAATKPAEVSASNKEKTYAAPTVANPVETTPVKTGEV
                     TKPAEKVEEAKDKKEEVTHQDAIDKSKLLTALSRAKKLESKLYTEASAANLQTSIQAG
                     QSLLGKADASEAELSAAESSIQSSIIGLELRSNSNKGTVSETPVAKKANIVEAKEETK
                     PAVTTTERSAVDSAILPISTAAKVETTSAPASTNEILKPSLSLSDARQNPAIRKEDVD
                     RGYSGFRTAGSGFRAAGSGFRAAGPENKPILNPNNTIAFSDISQGLHSFRGIGHSRGG
                     REIHYDVTTVRRGNRLNFTIKYSGPGEFVNNNFILDKGDGFGNPSNATITSSNPRVRE
                     QSKSISQGANYVSHSGYSMTSATSTNTEQTIRFSLPIINPNGDLSVRLKPVTFNVDQG
                     GGGAATSNDPYSNSNYYHRANPLLLDANPYGGTNNKTVSEDIDFQTVYLPTSKLPEGQ
                     TRLVREGEKGQRQITYKVHRFGNETLLGLPISNRVTKEAKPRIMQIGVAKELIDTVKP
                     RVDQNKVGDTNNLTFYLDNDGNGVYTEGVDELVQKIAIKDGAKGEKGDQGERGLTGAQ
                     GTKGEKGDQGERGLTGAQGAKGEKGEQGLQGRDGEQGPKGEDGKTPTVKVTDGQDGTH
                     TITINDGKGGITTTVVRDGFDGASPLVSTHRNEADKTTTVIFYYDLNDNNQFDEGDTK
                     LKEVVIADGKQGPKGDKGDNGKDGFTPEVTVTDNNNGTHTITITQPDNRPSLTTIVKN
                     GEDGKTPKVKAERDDAKKQTTLTFYIDKDGDGSYTAGKDELVQTTVVKDGQDGAAGAS
                     GRDGKEVLNGKADPTTEGKDGDTFVNTQTGDVFVKKGNTWEPAGNIKGPKGDKGADGA
                     KGEKGDRGERGLTGAQGTKGEKGDQGERGLTGAQGTKGEKGDRGERGLTGAQGQAGRD
                     AVTPTVTVKDNKNDGTHTITINDGRGNVASTVVRDGFDGASPLVATQRNEADKTTTVI
                     FYYDQNGNNELDASDKKLKEVIIADGAKGEQGLQGRDGQDGAQGQAGRDGKDVLNGKA
                     NPEVNQGKDGDKYVNTETGDVFVKNNGNWDKEGNIKGPKGDKGERGEDGKTPEVTVTP
                     GKDGHSTDITFTVPGKDPVTFTVKDGKNGKDGRAPKIKVEDITSPSRIRRDTDAAATP
                     TRNGIRVTVYDDVNDNGVYDEGVDKVLNSKDIYNGIDGRDGSAPTITTKDNGDGTHTI
                     TVQNPDSSESTTVVKDGKDGKTANITTTENPDGSHTITVTNPDGSTKETVVKNGKDGK
                     TPKVEVTDNNDGTHTVKVTDGDGNVTNAIIKDGKDGKAATATTTENPDGSHTVTITNP
                     DGTKNEFVVKNGRDGVDGRTPTASVRDNGDGSHTIVITNPEGVTTETTVRDGKSPKVT
                     ITDEQNGTHKISVLNGDGTTTETIIKDGKSPVATVRDNQDGTYTIRVENGNGTVSETT
                     VRDGKSPTAKVVDNGDGTHTITVVNSDGTTTTTTVRDGREPKLEVIDNNDGSHTIKVT
                     GADGKGTTTTIFDGKSPKANIVDNGDGTHTLTIVDSDGREYKSIIKDGKDGKDSVSPT
                     VTVKNNNDGTHVVTITNPDGSKTEMVIKDGKDGKCGCQDKPVTPSNDKPVPPTPNVPT
                     PEVPVKPVPAQPTPNVPTPEVPVQPTPAVPTPEVPVKPVPAVPEQPVVPTPAQPATPV
                     NANPVAPTTGKENRGDKLPETGSQSDYISVLLGSGILLSLYVGRRKED"
     gene            complement(41336..41884)
                     /locus_tag="VXB91_000128"
     CDS             complement(41336..41884)
                     /locus_tag="VXB91_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEV0469647.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALAGKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGVSALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLVEAIQ"
     gene            42205..42693
                     /locus_tag="VXB91_000129"
     CDS             42205..42693
                     /locus_tag="VXB91_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HEV0469648.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISGSFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEQVDQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGVSQEKAETVSKEKGAGEIDKITFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GL"
     gene            42690..43877
                     /locus_tag="VXB91_000130"
     CDS             42690..43877
                     /locus_tag="VXB91_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV0469649.1"
                     /translation="MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAAVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSTKEDNHFKVTVDQLEAA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTAILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            43870..44235
                     /locus_tag="VXB91_000131"
     CDS             43870..44235
                     /locus_tag="VXB91_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV0469650.1"
                     /translation="MIDHFEIKVKDLQISEGFYRSFLAPLDYKLAFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEEVQACYEAGLEAGGRDNGAPGYRSEHPIYY
                     AAFMIDLDGNNIEVVCHKE"
     gene            44251..45597
                     /gene="asnS"
                     /locus_tag="VXB91_000132"
     CDS             44251..45597
                     /gene="asnS"
                     /locus_tag="VXB91_000132"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HEV0469651.1"
                     /translation="MMTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVMNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            45750..46040
                     /locus_tag="VXB91_000133"
     CDS             45750..46040
                     /locus_tag="VXB91_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HEV0469652.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            46052..46522
                     /gene="ssbA"
                     /locus_tag="VXB91_000134"
     CDS             46052..46522
                     /gene="ssbA"
                     /locus_tag="VXB91_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HEV0469653.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF"
     gene            46554..46793
                     /locus_tag="VXB91_000135"
     CDS             46554..46793
                     /locus_tag="VXB91_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HEV0469654.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            47088..48488
                     /locus_tag="VXB91_000136"
     CDS             47088..48488
                     /locus_tag="VXB91_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HEV0469655.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILTGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSDVEEYI
                     SWAKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFDALEVFGMVEKELHFPQV
                     DIETVEGPLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGESIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDAIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            48490..48849
                     /locus_tag="VXB91_000137"
     CDS             48490..48849
                     /locus_tag="VXB91_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEV0469656.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHHLKKKK"
     gene            48903..49652
                     /locus_tag="VXB91_000138"
     CDS             48903..49652
                     /locus_tag="VXB91_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HEV0469657.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVNPYSNLNESEHYLLARHEITTNLEEICRSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            49642..49941
                     /locus_tag="VXB91_000139"
     CDS             49642..49941
                     /locus_tag="VXB91_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HEV0469658.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDMRRRLAIHNSGKGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALLKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            50012..50947
                     /locus_tag="VXB91_000140"
     CDS             50012..50947
                     /locus_tag="VXB91_000140"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HEV0469659.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMYKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            51033..51545
                     /locus_tag="VXB91_000141"
     CDS             51033..51545
                     /locus_tag="VXB91_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoylalanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HEV0469660.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGVVCQEPADFFESNHLYDLYVYPEMDIQSVKERACKHLGAPYNASFYPDAPGFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERNLHDSDF"
     gene            51570..52178
                     /locus_tag="VXB91_000142"
     CDS             51570..52178
                     /locus_tag="VXB91_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HEV0469661.1"
                     /translation="MFGELIRYLDQYEDVILREIKAQFPDVAVDKLMEEYIKAGLILR
                     ENKRYYLNFPTLESLDSLELDQEIFVREASPVYQALLEQSFETELRNQINAAILVEKT
                     DFARIKMTLSNYFYKVKQQYPLTEKQQELYDILGDVNPEYALKYMTAFLLKFLKKDQL
                     MQKCRDIFVDSLVVLGYIVQNEDGKYELAIDFDKERLTFYLA"
     gene            52279..52476
                     /locus_tag="VXB91_000143"
     CDS             52279..52476
                     /locus_tag="VXB91_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEV0469662.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVAKAKDVV
                     EDAKGAVEGAVEGLKNVFTKE"
     gene            complement(52519..53964)
                     /locus_tag="VXB91_000144"
     CDS             complement(52519..53964)
                     /locus_tag="VXB91_000144"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HEV0469663.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVVFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYVAEKDYEVGIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKLLAFTGTKGKTTAAYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALT
                     TPESIDLFDMMNQAVQNDRTHLIMEVSSQSYLVRRVYGLTFDVGVFLNISPDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVIINSDMDHFSVLKEQVKDQDHDFYGSQFDNQIENSKA
                     FSFSATGKLAGDYDIQLIGNFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGSTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMAIADEISSYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGADCYQIIQGKKESYPGDTAVAENYL"
     gene            54070..55692
                     /locus_tag="VXB91_000145"
     CDS             54070..55692
                     /locus_tag="VXB91_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEV0469664.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEHSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLALGLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLWSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
     gene            55896..57854
                     /locus_tag="VXB91_000146"
     CDS             55896..57854
                     /locus_tag="VXB91_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0469665.1"
                     /translation="MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
                     KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFL
                     MKALVSKSAIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFP
                     NSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTSKTSDIEKKSTQEAVLNK
                     NFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVASKMVNYG
                     KEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGV
                     SSIKQSIESVLGSDNVVIDIQQLTSDEFDSSGYFAQTAAQKDYDLYHGGWGPDYQDPS
                     TYLDIFNTNSGGVLQNLGLEPGEANDKAKAVGLDVYTQMLEEANKEQDPAKRYEKYAD
                     IQAWLIDSSLVLPSVSRGGTPSLRRTVPFAAAYGLTGTKGVESYKYLKVQDKIVTTDE
                     YAKAREKWLKEKEESNKKAQEELAKHVK"
     gene            58026..58259
                     /locus_tag="VXB91_000147"
     CDS             58026..58259
                     /locus_tag="VXB91_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HEV0469666.1"
                     /translation="MKLKLLRVDTKVIMGSFLLVLSSLLALLLPLILKGLIDGSSIEN
                     IGSKVFQSFLIFIGQALFSSIGYYLFSQSGEKR"
     gene            58265..59707
                     /locus_tag="VXB91_000148"
     CDS             58265..59707
                     /locus_tag="VXB91_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0469667.1"
                     /translation="MRKKVIEGLIYAEKSFFDKSQSGELTSAIVNDMSVIREFLITTF
                     PNIILSLVMVLGSIVVLFSLDWNLSLLLFITLPCMMFIILPLSNISEKYSRRLQEEIG
                     FLTGQLTEKIQEHELIKTNQAEKSVQDVLDNCIERVQNNSLKSDRVTSFETPFALLFI
                     FATIVVMLTYGGYRVSAGYISVGTLVSFLIYLFQLLNPISNIANFVTIYSSSKGSSVA
                     LENLLAVPKEKFEGGKSVSGQGLNFNHVYFGYDENRPVLKDITCSIFKGQKIAFVGPS
                     GSGKSTIVRLLERFYKPLSGDILMEQSSIYDFNLKEWRSKIAWVSQNNAVLSGSIRDN
                     LCLGLNRLVTDDELMKVLDLVSLGDEIRSMKEGLDTEVGERGRLLSGGRSQRLQIARA
                     YLKDAEILIFDEATANLDADSEYAIISSLYSVLKEKTVVIIAHRLSTVKDVDCIFFLE
                     EGKITGSGTHKELLENHERYARFVQEQMIE"
     gene            59865..60959
                     /locus_tag="VXB91_000149"
     CDS             59865..60959
                     /locus_tag="VXB91_000149"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEV0469668.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLAAIESADYALATSSGMSAIVLAFSVFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGHFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGAKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDARDLIADLRQALEG"
     gene            60967..62133
                     /locus_tag="VXB91_000150"
     CDS             60967..62133
                     /locus_tag="VXB91_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV0469669.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IHQAVQTYADQLVYGYTYASEDLIKEVQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSVKLNNRRLITNSLVEKDSLFEIDFDQLEKDLVEEE
                     VKLYVLCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVVDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVATFAKC"
     gene            62226..65324
                     /locus_tag="VXB91_000151"
     CDS             62226..65324
                     /locus_tag="VXB91_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV0469670.1"
                     /translation="MAKLIPGKIRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLIFCACDFFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLDRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINSQKYYVIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVPDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADANLFAFTVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKALPVDRQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQDIAQEEIDQAIQALVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLAYSLAHLFEGRDRVSFSQEFQNLAQDL
                     THPEDFPLQATQVKADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVAVVHGLKASREEILAESHQIYVTSY
                     ATFRQDSELYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMEDYQ
                     GASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELPDLGLTSFKITGSTPAKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLTGADTVILVDLWWNPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
     gene            65372..65989
                     /locus_tag="VXB91_000152"
     CDS             65372..65989
                     /locus_tag="VXB91_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEV0469671.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPIAEEKPVKPIEKQVGKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTTPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            66000..67334
                     /locus_tag="VXB91_000153"
     CDS             66000..67334
                     /locus_tag="VXB91_000153"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HEV0469672.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLYQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEAEGNDFVASDLLRSTTGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFSGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            67344..67808
                     /locus_tag="VXB91_000154"
     CDS             67344..67808
                     /locus_tag="VXB91_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0469673.1"
                     /translation="MEIPIKIIQASKSDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQYLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     ELDYKGIRLESPDELLSYFEMNGFVDEEATLLYATSQGYSMIWFNPFYLEEQ"
     gene            67805..68299
                     /locus_tag="VXB91_000155"
     CDS             67805..68299
                     /locus_tag="VXB91_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0469674.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            68380..70035
                     /gene="mltG"
                     /locus_tag="VXB91_000156"
     CDS             68380..70035
                     /gene="mltG"
                     /locus_tag="VXB91_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HEV0469675.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSTEELMADSLSTVEEIMRKAPTVPTHPSQGVPASPADEIQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPETPTPATETVDI
                     IRDTSRRSRREGAKPVKPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPI
                     DANSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQK
                     SMSTEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQAVGQLQGDFKESLTAETF
                     LAKVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDE
                     MLAAMDKNLSPYYSTIKSKNLTVNELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDM
                     PLQSNIAILYAQGKLGQNISLAEDVAIDTNIDSPYNVYKNVGLMPGPVDSPSLDAIES
                     SINQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            70106..70588
                     /gene="greA"
                     /locus_tag="VXB91_000157"
     CDS             70106..70588
                     /gene="greA"
                     /locus_tag="VXB91_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HEV0469676.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
     gene            71096..71494
                     /locus_tag="VXB91_000158"
     CDS             71096..71494
                     /locus_tag="VXB91_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0469677.1"
                     /translation="MENKESHKSQEIGNLIRVYNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAP
                     DFYQKHGYKEVFSLQDYLYIRQRYYYQKNL"
     gene            71939..72946
                     /locus_tag="VXB91_000159"
                     /pseudo
     CDS             71939..72946
                     /locus_tag="VXB91_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            73021..73221
                     /locus_tag="VXB91_000160"
     CDS             73021..73221
                     /locus_tag="VXB91_000160"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HEV0469678.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
     gene            73256..73972
                     /gene="atpB"
                     /locus_tag="VXB91_000161"
     CDS             73256..73972
                     /gene="atpB"
                     /locus_tag="VXB91_000161"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HEV0469679.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKLQTI
                     DGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            73986..74480
                     /gene="atpF"
                     /locus_tag="VXB91_000162"
     CDS             73986..74480
                     /gene="atpF"
                     /locus_tag="VXB91_000162"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HEV0469680.1"
                     /translation="MHVTVGELIGNFILITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            74480..75016
                     /locus_tag="VXB91_000163"
     CDS             74480..75016
                     /locus_tag="VXB91_000163"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HEV0469681.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            75031..76536
                     /locus_tag="VXB91_000164"
     CDS             75031..76536
                     /locus_tag="VXB91_000164"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HEV0469682.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYTGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPV
                     DDIVRFEEEFHAFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            76552..77430
                     /locus_tag="VXB91_000165"
     CDS             76552..77430
                     /locus_tag="VXB91_000165"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HEV0469683.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLADQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            77516..78922
                     /gene="atpD"
                     /locus_tag="VXB91_000166"
     CDS             77516..78922
                     /gene="atpD"
                     /locus_tag="VXB91_000166"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HEV0469684.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            78933..79352
                     /locus_tag="VXB91_000167"
     CDS             78933..79352
                     /locus_tag="VXB91_000167"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HEV0469685.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDHVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
BASE COUNT        24178 a        14670 c        17889 g        22683 t
ORIGIN      
        1 ggcgacttgt caatagaaaa ggaacaattt aattaaaaat attctggttt ttaattaaat
       61 tgtaagtcaa tgcaagtcaa taaggaattt tcagataatt attgaaaaag agacgttttt
      121 atgttataat gatagcgatt aaattcgagg tgaaaaatgg cacatttatt agaaaaaact
      181 agaaaaatta catcaatttt gaaacgctca gaggagcagt tgcaggatga gctcccttac
      241 aacgctatta cgcgtcagtt agcggatatt attcattgca atgcctgcat tatcaatagt
      301 aagggacgtc tgcttggcta ttttatgcgt tataaaacaa atacagatcg cgtagagcaa
      361 ttcttccaaa ctaagatttt cccagatgac tacgttcaag gggctaatat gatttacgaa
      421 acagaagcaa acttgcctgt tgagcatgat atgagtattt tccctgttga gagtagagat
      481 gattttccag atggcttgac gactattgca ccgattcatg tatcggggat tcgccttggt
      541 tctttgatta tttggcgtaa tgataaaaaa ttcgaagatg aggacttggt tcttgttgag
      601 attgccagta ccgttgttgg gattcagctt cttaacttcc aacgtgaaga agatgagaaa
      661 aatattcgtc gtcgtactgc tgtcaccatg gcggtcaata ccctttctta ctccgaactc
      721 cgtgctgttt cagcaatttt aggggaatta aatggaaatg aagggaagtt gactgcgtca
      781 gtgattgcag atcgtatcgg aatcactcgc tctgtgattg tcaatgctct tcgtaaactt
      841 gagtctgcgg ggattattga aagtcgctca cttggaatga agggaaccta tcttaaggtc
      901 ttgatttcag atatttttga agaagtgaag aaaagagatt actaatgaca aaggctttaa
      961 tttcgattga ttatacagaa gattttgttg ctgatagtgg gaagctgaca gcaggtgctc
     1021 cagctcaggc gatttcggat gccatcagca aggtaactcg attagctttt gaacgaggag
     1081 attatatctt ctttactatt gatgctcatg aagaaaacga ttgtttccat ccggaaagta
     1141 agttatttcc tcctcataat ctgattggga cgagtggacg gaatttatat ggagatttgg
     1201 ggatctttta tcaagagcat ggttcagaca gtcgtgtctt ttggatggat aaacgccatt
     1261 actcagcttt ttcagggact gacctagata ttcgtttgag agagcgtaga gtgtctaccg
     1321 ttatcttaac aggtgtcttg acggatatct gtgtcctaca tacagctata gatgcctata
     1381 atctaggata tgacatcgag attgttaaac cagctgttgc ttccatctgg cctgaaaatc
     1441 atcaatttgc cctaggtcat ttcaaaaata cactcggagc taagttagta gatgaaaatc
     1501 taaatgaact ttctgagtaa cctggttggt gaaaatgaaa aaatttgaaa aaaagtgttg
     1561 acaagcatcc caaaagttga tatactagta aagtaatcga tgcggggatg gcggaattgg
     1621 cagacgcgca ggactaagga tcctgtgacc gctttaggtc gtgagggttc aagtccctct
     1681 ctccgcatag gaaaagagtt agctaaagct agctcttttg tatttctcta aaaaattaga
     1741 atccagtcaa atgtagtgga gaatcagcga aaatatggga aaactgatcc ttgtttctgc
     1801 ttttgtcata gaagaataat aaagattatc ttcttcaaat tctccgatat tctctaaagt
     1861 tttgtgcaag ttgcacagaa cttttttatt tttttggtca tcttgccata gaaatataaa
     1921 gcgttttcat ctataatata attatcaaaa gacaaaagga gttcacctca tggtagaatt
     1981 gaatcttaaa aatatttaca aaaaatatcc aaacagcgaa cactattcag ttgaagattt
     2041 caacttgaac atcaaagata aagaatttat cgttttcgta ggaccttcag gatgtggtaa
     2101 atcaactaca ctccgtatga ttgctggtct tgaagacatc acagaaggta ctgcatctat
     2161 cgatggcgtg gttgtcaacg acgtagctcc aaaagaccgt gatatcgcca tggtattcca
     2221 aaactacgct ctttacccac acatgactgt ttatgacaac atggctttcg gtttgaaatt
     2281 gcgtaaatac agcaaagaag acattaacaa acgtgttcaa gaagcagctg aaatacttgg
     2341 attgaaagaa ttcttggaac gtaaaccggc tgacctttca ggtggtcaac gtcaacgtgt
     2401 tgccatgggg cgtgcgattg tccgtgatgc gaaagtattc ttgatggacg aacctttgtc
     2461 aaacttggat gccaaacttc gtgtatcaat gcgtgctgaa atcgctaaaa ttcaccgtcg
     2521 tatcggagct acaactatct atgtaactca cgaccaaaca gaagcgatga cacttgcaga
     2581 ccgtatcgtt attatgtcag ctactaagaa ccctgctggt acaggtacta tcggacgtgt
     2641 agaacaaatc ggtactcctc aagaagttta caaaaatcca gttaacaaat tcgttgcagg
     2701 attcatcgga agcccagcta tgaacttcat caacgtgaaa ttggttggta gcgaaattgt
     2761 ttctgacggt ttccgtttga aagtgccaga aggagcattg aaagttcttc gtgaaaaagg
     2821 ctacgaagga aaagaattga tctttggtat ccgtccagaa gacgtgaatg cagaacctgc
     2881 tttccttgaa acattcccag actgtgttgt aaaagcgact atctctgtat cagaactgct
     2941 tggttcagaa tctcaccttt actgccaagt tggtaaagac gagtttgttg caaaagttga
     3001 tgctcgtgac tacttgcaaa caggtgcaac agttgagctt ggatttgact tgaacaaagc
     3061 acacttcttc gatgtagaaa ctgaaaaaac aatctactaa gaataaataa aattcaaagc
     3121 actacaagaa aagatatctc tttatcaatt gtagtggaga gatatcagtt aatctaggga
     3181 gagaaacaaa atgcttctct cctttttgct agggaagtca tattatacat ctatattgtg
     3241 atgctcttta tactcttcga aaatctcttc aaaccacgtc aacgtcgcct tgccgtacgt
     3301 atgattactg acttcgtcag ttttatctgc aacctcaaag ctgtactttg agtagcttac
     3361 ggctagtttc ctagtttgct ctttgatttc cattgagtat tatttgtggg taccatctac
     3421 aagtgaagct atatgcgtaa actacgtgag caattgaatt cgaactagag aggtaataat
     3481 aaatttatgc tatagttatg gtgacttgta tgcttttgat tctagtttat caaataatag
     3541 attagaattg tcagataata tcattttgtg ttataatgaa gaaaaaacag aggtgttcaa
     3601 atgtcagaag caggtcataa gtttttagca aaattgggga aaaaacgctt acgtccaggt
     3661 ggaaagcgtg ccacagattg gttaattgca gaaggaggat tttcaaaaga aaagagaata
     3721 ctagaggttg cgtgtaatag gggaactaca gcaattgagt tggcacagcg ttttggttgc
     3781 aagataactg ctgttgatat ggatgctcaa gctttagaag tggctaaaaa atctgctgga
     3841 acggcaggtg ttgctcattt aatcagtttt gaaagagcaa atgcaatgaa acttccttat
     3901 caagatgcta gttttgatat tgttataaat gaagctatgc tgactatgca agccgatcaa
     3961 gctaagaaaa aatgtgtaat ggaatatcta agggtattaa aacctggagg tcttctcttg
     4021 acacatgatg tgcttcttaa ggaagctaaa gagtctatca gacaggaatt atcacaagca
     4081 attcatgtaa atgtaggtcc tttaactcaa gatggttggg aacaggtgat gatagaatca
     4141 ggttattgtg atgtgaaagc attgactggt gaaatgacat taatgaaatt atcgggtatg
     4201 atttatgacg aaggtttgct aggaactttg aaaatttgtg taaatgcttg taaaaaggag
     4261 aatagaaagc agtttttaac tatgtataaa atgtttgcta agaataaaca gaaattgggc
     4321 tttattgcga tggctagtta taaatcgtca aaacgttaga taattattga agttaacttt
     4381 tccttttttc tttcttaaaa aatatgctat aatagagagt aaaaaacttt gaaagaaaga
     4441 aaaaagatga atttaaaaga ttacattgca acaattgaaa attatccaaa ggaaggcatt
     4501 accttccgtg atattagtcc tttgatggct gatggaaatg cttatagcta cgctgttcgt
     4561 gaaatcgttc agtatgctac tgacaagaaa gtcgacatga tcgtgggacc tgaagctcgt
     4621 ggatttatcg tgggttgtcc agttgccttt gagttgggaa ttggttttgc gcctgttcgt
     4681 aagccaggta aattgccacg cgaagttatt tctgctgact atgaaaaaga gtacggtgtc
     4741 gataccttga ctatgcacgc ggatgccatt aagccaggtc aacgtgttct tattgtagat
     4801 gaccttttgg cgacaggtgg aactgttaag gcaactatcg agatgattga aaaacttggt
     4861 ggtgttatgg caggttgtgc cttccttgtt gaattggatg aattgaacgg ccgtgaaaaa
     4921 atcggtgact acgactacaa agttcttatg cattattaat gaaaacagtc cctagggctg
     4981 ttttctctac actaggatat aaaaatagac tataactagt tagagaaaaa ctataattga
     5041 aaactatatc ttcttgcagt ataataaaag gactaagtgt ttgagatttg tcttcaaaca
     5101 catgcaatta ttcctgagag agtacagtta ggagagggtt atgccgattc gaattgataa
     5161 aaaattgcca gctgttgaga ttttacggac agagaatatc tttgtcatgg atgatcaacg
     5221 tgctgcccac caagatatcc gtcctttgaa gattttaatt ttaaatctca tgccacagaa
     5281 aatggtcaca gagacccagt tgttgcgcca cttggctaat acacccctac aactggatat
     5341 tgattttctc tatatggaga gccaccgttc taaaacaact cgttcagagc acatggagac
     5401 cttctataaa acttttcctg aagtcaagga tgagtatttt gatgggatga tcatcacggg
     5461 tgctccagtt gagcatttac catttgagga agtggactat tgggaggaat ttagacagat
     5521 gcttgagtgg tctaagactc atgtctattc gacccttcat atctgttggg gagctcaggc
     5581 tgggctttat ctgcgctatg gtgtagaaaa ataccagatg gacagtaagc tatcaggtat
     5641 ttatcctcag gacaccctaa aagagggtca ccttctattt agaggctttg atgatagcta
     5701 tgtatcccct cattcacggc acacggagat ttctaaggaa gaggtcttaa acaagactaa
     5761 tctcgagatt ttatcagaag gacctcaggt tggggtttct attttggcca gtcgtgattt
     5821 acgagaaatt tatagttttg gtcatttgga gtatgaccgt gataccttgg caaaagagta
     5881 ttttcgagat cgtgatgcag gtttcgaccc acatattcca gaaaattact ttaaagatga
     5941 tgatgttaat caggtacctt gtctttgttg gtcttcatct gcagccctct ttttcagtaa
     6001 ttgggtaaac catgcggtct atcaggagac gccttttgac tggagaaaga tagaagatga
     6061 tgcatctgca tatgggtatt tataagagga attatgacat atttagacgc ttttaaatca
     6121 ggtaccttgg ttttaccgag tgccctgctc ttgcatttta aggaactctt tccttctagc
     6181 gacgattttc tggtttggca atttttctat ttgcaaaata cgacaggctt agaagaaatg
     6241 tcgccaagcc agattgctga aaggattggc aaggaaattt cggatgtcaa ccagtccatt
     6301 tctaatctga cggaaagggg actgctccag tatcgtacta tcgaattaaa tggcgaaatt
     6361 gaattgctct ttgatgctag tttggccttg gaacgtttgg atgacctgtt tggagcagtt
     6421 cattcaagtt cagaccagct aacaccacaa aaccagctca aggatttggt ggaaaccttc
     6481 cagcaggagt tgggacgatt gttgacgcct tttgagattg aggatttgac caagacacta
     6541 aaggaagatg gaaccagtgc tgacttgatt aaggaggctc ttcgtgaagc tgttttgaat
     6601 ggaaaaccaa actggaagta cattcaggcg attttgagaa actggcgcca tgaaggaatc
     6661 aagagtgtgg ctcaaattga ggccaagaga gcagaaagag aagcaagcaa tcctcagttg
     6721 acacaggtat ctgcagattt cagaaatgcc atggatctct ggaaggatta atccatgcaa
     6781 gtaggcttga aatccgagta agatttgcaa gctgtgtata attgtgatag aataaataga
     6841 aaataaattg aaaaaagagg tatgtgaaat gtcacgtaaa ccatttatcg ctggtaactg
     6901 gaaaatgaac aaaaatccag aagaagctaa agcattcgtt gaagcagttg catcaaaact
     6961 tccttcatca gatcttgttg aagcaggtat cgctgctcca gctcttgatt tgacaactgt
     7021 tcttgctgtt gcaaaaggct caaaccttaa agttgctgct caaaactgct actttgaaaa
     7081 tgcaggtgct ttcactggtg aaactagccc acaagttttg aaagaaatcg gtactgacta
     7141 cgttgttatc ggtcactcag aacgccgtga ctacttccat gaaactgacg aagatatcaa
     7201 caaaaaagca aaagcaatct ttgcgaacgg tatgcttcca atcatctgtt gtggtgaatc
     7261 acttgaaact tacgaagctg gtaaagctgc tgaattcgta ggtgctcaag tatctgctgc
     7321 attggctgga ttgactgctg aacaagttgc tgcctcagtt atcgcttatg agccaatctg
     7381 ggctatcggt actggtaaat cagcttcaca agacgatgca caaaaaatgt gtaaagttgt
     7441 tcgtgacgtt gtagctgctg actttggtca agaagtcgca gacaaagttc gtgttcaata
     7501 cggtggttct gttaaacctg aaaatgttgc ttcatacatg gcttgcccag acgttgacgg
     7561 tgcccttgta ggtggtgcgt cacttgaagc tgaaagcttc ttagctttgc ttgactttgt
     7621 aaaataatca gtaagtagca aaagctaggt ggaacagcat tcagatgtct gttacatttt
     7681 ttataggaga gcaaagattg aaaacaaaaa ttggattagc aagtatctgt ttactaggct
     7741 tggcaactag tcatgtcgct gcaaatgaaa ctgaagtagc aaaaacttcg caggatacaa
     7801 cgacagcttc aagtagttca gagcaaaatc agtcttctaa taaaacgcaa acgagcgcag
     7861 aagtacagac taatgctgct gcccactggg atggggatta ttatgtaaag gatgatggtt
     7921 ctaaagctca aagtgaatgg atttttgaca actactataa ggcttggttt tatattaatt
     7981 cagatggtcg ttactcgcag aatgaatggc atggaaatta ctacctgaaa tcaggtggat
     8041 atatggccca aaacgagtgg atctatgaca gtaattacaa gagttggttt tatctcaagt
     8101 cagatggggc ttatgctcat caagaatggc aattgattgg aaataagtgg tactacttca
     8161 agaagtgggg ttacatggct aaaagccaat ggcaaggaag ttatttcttg aatggtcaag
     8221 gagctatgat gcaaaatgaa tggctctatg atccagccta ttctgcttat ttttatctaa
     8281 aatccgatgg aacttatgct aaccaagagt ggcaaaaagt gggcggcaaa tggtactatt
     8341 tcaagaagtg gggctatatg gctcggaatg agtggcaagg caactactat ttgactggaa
     8401 gtggtgctat ggcgactgac gaagtgatta tggatggtgc tcgctatatc tttgcggcct
     8461 ctggtgagct caaagaaaag aaagatttga atgtcggctg ggttcacaga gatggtaaac
     8521 gctatttctt taataataga gaagaacaag tgggaaccga acatgctaag aaaatcattg
     8581 atattagtga gcacaatggt cgtatcaatg attggaaaaa ggttattgat gagaacgagg
     8641 tggatggtgt cattgttcgt ctaggttata gcggtaaaga agacaaggaa ttggcgcata
     8701 acattaagga gttaaaccgt ctgggaattc cttatggtgt ctatctctat acctatgctg
     8761 aaaatgagac cgatgctgag aatgacgcta aacagaccat tgaacttata aagaaataca
     8821 atatgaacct gtcttaccct atctattatg atgttgagaa ctgggaatat gtaaataaga
     8881 gcaagagagc tccaagtgat acagacactt gggttaaaat catcaacaag tacatggaca
     8941 cgatgaagca ggcgggttat caaaatgtgt atgtctatag ctatcgtagt ttattacaga
     9001 cgcgtttaaa acacccagat attttaaaac atgtaaactg ggtagcggct tatacgaatg
     9061 ctttagaatg ggaaaaccct tattattcag gagaaaaagg ttggcaatat acctcttctg
     9121 aatacatgaa aggaatccaa gggcgcgtag atgtcagcgt ttggtattaa gcgatgattt
     9181 gaaagaggga tgtgatagta gcaccctctt tttctttgtt ttatgatagt tcatcctcga
     9241 gtaaattcaa gatcttgctc ggaaatgaag cttatatagt agattgaata tagacaaata
     9301 ccttgtgatt ggtaaaacat tttagaaatt catttacctt tcctaatcga cttggtttca
     9361 tcttatttca atctattata gtattgggga atttcttcaa accacatcag cttggtcagt
     9421 tctacctgcg acctcaaaac ttgtgctttg gtcaagctgg gtttagtttc ctagtttgct
     9481 gatggatttc cattgactat aagcatccaa ccctcttttt gtcttctaaa gaattcttaa
     9541 attatcagtc tattgcaact tttctcatgt gggtcatttg gcttgcaatt gtctttcctt
     9601 agtagtatac tgaggtagta atcattaaga agtggttaca taaaaataat gaatgaggta
     9661 aaataaaatg gtagaattga aaaaagaagc agcaaaagat gtcgcaacat taacaaaagc
     9721 agcgccagta gcattggcaa aaacaaagga agttttgaat caagcagttg ctgatttgta
     9781 tgtagctcac gttgctttgc accaagtgca ctggtatatg catggtcgtg gtttccttgt
     9841 atggcatcca aaaatggatg agtacatgga agctcttgat ggtcatttag atgaaatcag
     9901 cgaacgcttg atcacacttg gtggaagccc attctctact ttgacagagt tccttcaaaa
     9961 cagtgaaatc gaagaagaag ctggtgaata ccgtaatgtt gaagaaagct tggaacgtgt
    10021 tctagctatt tatcgctacc tcatcactct tttccaaaaa gcgttggatg tgactgacga
    10081 agaaggcgat gatgttacaa acgatatttt tgttggtgct aaggctgaac ttgagaaaac
    10141 agtttggatg cttgccgcag aacttggaca agcacctggt ttgtaagaaa caagacaaca
    10201 tagataaata tgtaggaaat ttcttacaga ttttttctat tttgtaagct attccaaacc
    10261 agtctttttt tgagtttttt gataaaatag tactatcagt gaaaaggatg gaagcatgac
    10321 taagaaaatc gtagctattt gggcccagga tgaagagggt gtgattggta aggacaatcg
    10381 tctgccttgg catttgccag cagaattgca gcactttaaa gaaacaactc tgaatcatgc
    10441 tatcttgatg gggcgggtaa cctttgatgg aatggggcgt cgcttgcttc caaaacggga
    10501 gaccctgatt ttgacgcgta atccggaaaa aaagatagat ggggttgcta cttttcagga
    10561 cgtccagtct gttcttgact ggtatcaggc tcaagaaaag aatctctaca ttatcggtgg
    10621 gaagcaaatt tttcaggctt ttgaagctta ccttgatgaa gtgattgtca ctcacattca
    10681 tgctcgggtg gaaggagata cctatttccc tgaagagctt gacttgtctc tttttgagac
    10741 agtttcaagc aaattttacg ccaaagatga gaagaatcct tatgatttta ccatccaata
    10801 ccgcaagaga aaggaagttt aatggaacgg agtttatttg gtctattcac ggcttttctg
    10861 tgtttcatct gctttctggc aggagcacaa gcttttcgta aaaagcgtta cgggctttct
    10921 atcctccttt ggttaaatgc ctttaccaat ctggtcaata gtattcatgc tttttacatg
    10981 accttatttt agatagaatg acagtataga atggaaggaa atcatgtcta caaatagaaa
    11041 aaatgatatg atggtttatt gctcattttg tggcaaaaac caagaagaag tacaaaaaat
    11101 aattgctggc aacaatgctt ttatttgtaa tgaatgcgtg gagttagctc aggaaatcat
    11161 tcgagaagaa ttggttgagg aagtcttggc agacttgtct gaggtgccaa aaccaattga
    11221 actcctccat atcttgaacc actatgtaat tggtcaagat cgtgccaagc gtgccttggc
    11281 agtggcggtt tataaccact acaaacgcat caatttccac gatacacgcg aagagtcaga
    11341 agatgtggat ttgcagaagt caaacatttt gatgattggc ccaactggtt cagggaaaac
    11401 tttccttgcc cagaccttgg ctaagagctt gaatgtacct tttgctattg cggatgcgac
    11461 agctctgacg gaggctggtt atgtgggtga ggatgtggaa aatatactcc tcaaactctt
    11521 gcaggttgct gactttaaca tcgaacgtgc agagcgtggc attatctatg tggatgaaat
    11581 tgacaagatt gccaagaaga gtgagaatgt gtctatcaca cgtgatgttt ctggtgaagg
    11641 ggtgcaacaa gcccttctca agattatcga gggaactgtt gctagcgtac cgcctcaagg
    11701 tggacgcaaa catccacaac aagagatgat tcaagtggat acaaaaaata tcctcttcat
    11761 cgtgggtggt gcttttgatg gtattgaaga aattgtcaaa caacgtctgg gtgaaaaagt
    11821 catcggattt ggtcaaaaca ataaggcgat tgacgaaaac agctcataca tgcaagaaat
    11881 catcgatgaa gacattcaaa aatttggtat tatccctgag ttgattggac gcttgcctgt
    11941 ttttgcggct cttgagcaat tgaccgttga tgacttggtt cgcatcttga aagagccaag
    12001 aaatgccttg gtgaaacaat accaaacctt gctttcttat gatgatgttg agttggaatt
    12061 tgacgacgaa gcccttcaag agattgctaa taaagcaatc gaacggaaga caggggcgcg
    12121 tggacttcgc tccatcatcg aagaaaccat gctagatgtt atgtttgagg tgccgagtca
    12181 ggaaaatgtg aaattggttc gcatcactaa agaaactgtc gatggaacgg ataaaccgat
    12241 cctagaaaca gcctagaggt gactatggaa cttaatacac acaatgctga aatcttgctc
    12301 agtgcagcta ataagtccca ctatccgcag gatgaactgc cagagattgc cctagcaggg
    12361 cgttcaaatg ttggtaaatc cagctttatc aacactatgt tgaaccgtaa gaatctcgcc
    12421 cgtacatcag gaaaacctgg taaaacccag ctcctgaact tttttaacat tgatgacaag
    12481 atgcgctttg tggatgtgcc tggttatggc tatgctcgtg tttctaaaaa ggaacgtgaa
    12541 aagtgggggt gcatgattga ggagtactta acgactcggg aaaatctccg tgcggttgtc
    12601 agtctagttg accttcgtca tgccccgtca gcagatgatg tgcagatgta cgaatttctc
    12661 aagtattatg agattccagt catcattgtg gcgaccaagg cggacaagat tcctcgtggt
    12721 aaatggaaca agcatgaatc agcaatcaaa aaaaaattaa actttgaccc gagtgacgat
    12781 ttcatcctct tttcatctgt cagtaaggca gggatggatg aggcttggga tgcaatctta
    12841 gaaaaattgt gaggaaaaga aaatggcaaa aacaattcat acagataagg ccccaaaggc
    12901 tatcggaccc tatgttcaag gaaaaatcgt tggcaacctt ttgtttgcta gcggtcaagt
    12961 tcccctatcc cctgaaactg gggaaattgt aggagagaat atccaagaac agacagagca
    13021 agtcttgaaa aacatcggtg ctattttggc agaagcagga acagactttg accatgttgt
    13081 caaaacaact tgcttcttga gcgatatgaa cgactttgtt ccttttaatg aggtttacca
    13141 aacggccttc aaagaggaat tcccagctcg ttcagctgtg gaggtagctc gtcttcctcg
    13201 tgatgtaaaa gtcgaaattg aagtcatcgc agagattgga taagctagtt gaagtttggt
    13261 gttgccaaac ttcttttgat ataaggagaa aaagatgaca aagaaacaac ttcacttggt
    13321 gattgtgaca gggatgagtg gcgcagggaa aactgtagcc attcagtcct tcgaggatct
    13381 aggttatttc accattgata atatgccgcc agctctcttg cctaagtttt tgcagctggt
    13441 tgaaattaag gaagacaatc ctaagttggc cttggtagtg gatatgcgta gccgttcttt
    13501 cttttcagag attcaagctg ttttggatga gttggaaaat caagatggtt tggatttcaa
    13561 aatcctcttt ttggatgcgg ctgataagga attggtcgct cgttacaagg aaaccagacg
    13621 gagtcaccca ctagcagcag acggtcgtat tttagatgga atcaagttgg aacgtgaact
    13681 cttggcacct ttgaaaaata tgagccaaaa tgtggtggat acgactgaac tcactccacg
    13741 tgagctgcgt aaaacccttg cagagcagtt ttcagaccaa gaacaagccc agtctttccg
    13801 tatcgaagtc atgtctttcg gatttaaata tggaatcccg attgatgcgg acttggtctt
    13861 tgatgtccgt ttcttgccaa atccctatta tctaccagaa ctgagaaacc aaacgggtgt
    13921 ggatgaacct gtttatgatt atgtcatgaa ccatcctgag tcagaagact tttatcaaca
    13981 tttattggcc ttgattgagc cgattctgcc aagttaccaa aaggaaggta agtccgtttt
    14041 gaccattgct atgggatgta cgggtggaca acaccgtagt gtggcatttg ctaaacgctt
    14101 ggtgcaggac ttatccaaga attggtctgt taatgaaggg catcgcgaca aagaccgcag
    14161 aaaggaaacg gtaaaccgtt catgagaaaa ccaaagataa cggtgattgg tggagggact
    14221 ggaattcccg tcattctaaa aagtctgcgg gaaaaagatg tggaaatcgc agctatcgtg
    14281 acggtggcag atgatggtgg ttcttcaggt gaactccgaa aaaatatgca acagttgaca
    14341 ccgccaggtg atcttcgtaa tgtccttgtg gccatgtcgg atatgcctaa gttttatgag
    14401 aaggtctttc agtatcggtt ctctgaggat gccggagcct ttgctggcca tccattggga
    14461 aatctcatca ttgctggctt gtcagaaatg cagggttcaa cctataatgc catgcagtta
    14521 ttgagcaaat ttttccatac aacagggaaa atttatcctt ccagtgacca tcctttgacc
    14581 cttcatgcag tctttcagga tgggacagaa gtggctggag agagtcatat tgtagaccat
    14641 cgaggcataa ttgacaatgt ctatgtgacc aatgccctaa acgatgatac gcctctggcc
    14701 agccgtcgag tagtgcagac catccttgaa agtgacatga ttgtcctagg gccaggttcc
    14761 ctctttacct ctattttgcc caatatcgtg attaaggaaa ttgggcgggc tcttttggaa
    14821 actaaggcag aaattgccta tgtctgcaat atcatgaccc aacgtgggga gacggaacac
    14881 tttacagata gcgaccacgt ggaagtcttg catcgtcacc ttggtcgccc ttttatcgac
    14941 actgtcttgg tgaatattga aaaagtgcct caggaataca tgaattccaa ccgttttgat
    15001 gaatacttag tgcaagtgga acacgatttt gtaggtcttt gtaagcaagt ttcgcgcgtg
    15061 atttcatcta acttccttcg tctggaaaat ggcggtgcct tccacgatgg agatttgatt
    15121 gtggacgagt tgatgcgcat tatacaggtg aaaaaatgag tttcacagta gcagtaaaag
    15181 aagaaatcct gggccaacac catctgagcc ggcatgaatt atctgccatt atcaaaatgt
    15241 ctggtagcat cggtctctcg acttcgggct tgactttgtc agttgtgaca gaaaatgcca
    15301 aactggcccg tcacctctat gagtcctttc tccatttcta tgaaatcaaa tctgaaattc
    15361 gtcaccacca acggagcaat cttcgcaaga atcgcgtcta taccgttttt acagatgaaa
    15421 aggtgcagga tttgttaagt gatttgcact tggcagactc tttctttggc ctggaaacag
    15481 gtattgatga ggcgatttta tcggacgagg aagcaggtcg tgcctatctc tgtggcgctt
    15541 tcttggcaaa tgggagcatt cgtgaccctg agtcaggcaa gtaccagttg gaaatcagtt
    15601 ctgtttatct ggaccacgcg caaggaattg cctcccttct ccaacagttt ttactggatg
    15661 ccaaggtgct tgagcgcaag aagggggctg tgacctatct ccagcgagca gaagacatta
    15721 tggacttctt gatagtaata ggagccatgc aggcacgtga tgattttgag cgggttaaga
    15781 ttttgcgaga aacccgtaac gacctcaatc gggctaataa tgccgagaca gctaatatcg
    15841 ctcggacagt ttctgccagc atgaagacca ttaacaatat cagtaaaatc aaagatatca
    15901 tgggcttaga aaatttgcca gtagatttgc aggaagtggc gcaactgagg attcagcacc
    15961 cagactactc tatccagcag ttagcagata gtctcagcac ccctctgacc aaaagtggtg
    16021 tcaatcacag actcagaaaa atcaataaga tagcggatga attataaaac cacgaatcct
    16081 atgtgactcg tggttctttt ttataaactg gtagagtgtt ttggttgtac tttttgttca
    16141 gggtcaatgt agttgatagc gttgttgaca gcagttggag cttctccgag gcctgtcgca
    16201 atcagatcaa tttttccgtc atagtagcag cagtcaccga tagcatagat acctgcttgg
    16261 ctggattcct gtttgctgtt gacgataatc ttgtgacggt tgaggtcgag cccccagttt
    16321 ttaaggttac cgacagaaga tttgaaacca tagttgacaa agaggtggtc taggtcaatg
    16381 gtttcagttt catcagattt gacttttgtg atttcaagtt tatcaagtgt ttttccattt
    16441 ccaaggagtt ggctaggggc gaatggtgtc ttgatggtta cagatgattc ttgcaaggtt
    16501 tgaacactgt gttccaaggc acggaaatta tctctgcggt gaacaagggt agttggtgcg
    16561 attttttcaa aagccaaagc ccaatccaca gccgagtctc ccccaccaag aatcgtcact
    16621 ttcttaccag cgtattgctg aatgttagaa acgtggtagt ggatattttc atagtcctca
    16681 accccttcaa gttccagcgg acgtggtttg aaggcaccgc cacccatagc gatgataact
    16741 gttttagtca ggtgacttcc tttggaagtt gtgatggcaa attcttcttc ttgtttgtca
    16801 atctcaagaa ccgtttcatt gagatgaata ggggtatcaa atccatttag ctgttcaatc
    16861 aagcggttag tcaactcttc tccagtcagg tttgggaagc ctggtacgtc taggatttcc
    16921 ttttcagggt agagaatagc aggttgtcca cctagctggg gaagagagtc gatgatttga
    16981 accttggctt ggcgtaggtg ggcataaaag gctgcaaaaa gcccgacagg accaccaccc
    17041 acaatggtaa tatcatagag ttgagacata gtttctcctt tgttttttct agtcagttta
    17101 ttttatcata tttttgttca atgtaaaatg gactaggata gggaaaaaaa tgccagaaaa
    17161 tggtataata ggacgaaagt gttttgatag ggaggatatc agggatgaat tttcaacaat
    17221 tatccaatct gcaatattgg accagtttgt ttgcaagtcc atggacgata gctatcaatc
    17281 tgattgatat tttgattgtt gcttatattt tataccattt tacaaaagct attgcaggaa
    17341 ccaagattat gattttggta cgtggagttt tggtgtttat tttagctcaa atccttgcaa
    17401 atatgattgg tttgactacg atttcttggt taatcaatca aattattact tatggggtta
    17461 ttgcggcggt tgttatcttc tctccagaga ttcggactgg tttggaacgt ttgggaagag
    17521 cgacagattt cttttccaat gcccctatta gtgctgagga acagatgatt cgtgcctttg
    17581 ttaagtctgt tgaatacatg agtcctcgta aaatcggggc cttggttgct attcagcgtg
    17641 tacgtacctt gcaggagtat atgtcgacag gaattccctt ggatgctaag atttctgcag
    17701 aacttctcat taacattttt attcccaaca ctcccctaca tgacggtgcg gtgattatca
    17761 aagaagaacg tatcgctgtg acgtctgcct atctgccctt gacaaaaaac acagggattt
    17821 ccaaggaatt tgggaccaga caccgggcgg ctatcggttt atcagaagtc tcagatgcct
    17881 tgacttttgt cgtatcagag gaaacgggag gaatttcgat aacctataat ggaaggttta
    17941 agcacaacct aacacttgat gaatttgaaa cagaattacg tgaaatctta cttccaaaag
    18001 aggaagtggg tcttagtttt aaagaacgat tgctaggagg atggaaacat gaaaaaaaat
    18061 agtttatata tcatatcctc actctttttt gcttgtgtct tatttgtcta tgctacggcg
    18121 acgaattttc aaaacagtac cagtgctagg caggtaaaaa cggaaaccta tactaataca
    18181 gtaaccaatg tccctattga catacgctat aatagtgata agtattttat tagcggtttt
    18241 gcttcagaag tatcagtggt cttgactggt gcaaatcgcc tatcgctagc tagtgaaatg
    18301 caagaaagta cacgtaaatt caaggttact gctgacctaa cagatgccgg tgttggaacg
    18361 attgaagttc ctttgagcat tgaagattta cccaatgggc tgaccgctgt ggcgactccg
    18421 caaaaaatta cagtcaagat tggtaagaag gctcagaagg ataaggtaaa gattgtacca
    18481 gagattgacc ctagtcaaat tgatagtcgg gtacaaattg aaaatgtcat ggtgtcagat
    18541 aaagaagtgt cgattacgag tgaccaagag acattggata gaattgataa gattatcgct
    18601 gtcttgccaa ctagcgaacg cataacaggt aattacagtg gttcagtacc tttgcaggca
    18661 atcgatcgca atggtgttgt cttaccggca gttatcactc cgtttgatac aataatgaag
    18721 gtgactacaa aaccagtagc accaagttca agcacatcaa attcaagtac aagcagttca
    18781 tcggagacat cttcgtcaac gaaagcaact agttcaaaaa cgaattaaaa atagaaaagg
    18841 attttataac aatgggtaaa tattttggga ctgatggagt ccgtggagaa gctaacctag
    18901 agctaacacc agaattagcc tttaaactag gacgttttgg aggctatgtt cttagtcaac
    18961 atgaaacgga agcgccgaaa gtctttgtag gacgtgacac acgtatttca ggggaaatgc
    19021 tggaatcggc cttggtggca ggtctccttt cagtagggat tcacgtatac aaacttggtg
    19081 tccttgcaac accagcagta gcttacttgg ttgaaactga aggagcaagt gccggtgtca
    19141 tgatttctgc tagccacaac ccagcccttg ataacggaat caagttcttt ggcggtgatg
    19201 gcttcaaact agatgatgaa aaagaagcag aaattgaagc cttgctagat gctgaggaag
    19261 acactcttcc tcgtccaagt gcagaaggct taggaatttt ggtagattat ccagaaggct
    19321 tgcgtaagta tgaaggatac cttgtttcaa ctggaactcc tcttgatgga atgaaggttg
    19381 ccttggatac agctaatgga gcagcttcta ccagtgcccg tcaaatcttt gcagaccttg
    19441 gtgcccaatt gacggttatc ggggaaacac cagacggtct taacatcaac cttaatgttg
    19501 gttcaacaca tccagaagcc cttcaagaag tggtcaaaga aagtgggtca gctattggtt
    19561 tggcctttga tggagacagt gaccgcttga ttgctgttga tgagaatggt gacatcgtcg
    19621 atggtgacaa gattatgtac atcatcggaa aatacctttc tgaaaaagga caattggctc
    19681 aaaatacaat tgtgacaact gttatgtcta accttggttt ccacaaggcc ttgaatcgcg
    19741 aaggtattaa caaggcagtt actgcagttg gtgaccgcta cgttgttgaa gaaatgagaa
    19801 aatcaggtta caaccttggt ggtgaacagt ctggtcacgt tatcttgatg gattacaata
    19861 ccacaggtga tggtcaatta tcagcagttc aattgactaa aatcatgaag gaaactggta
    19921 agagcttatc agagttggcg gcagaagtaa cgatttatcc acaaaaatta gttaatatcc
    19981 gagtggaaaa cgtcatgaag gaaaaggcca tggaagtgcc agctatcaag gccatcatcg
    20041 agaagatgga agaagaaatg gcggggaacg gccgtatcct tgttcgtcca agtggaacag
    20101 aacccctctt gcgtgttatg gcagaagcgc ctacaacaga agaagtagac tactatgttg
    20161 ataccatcac agatgtagtt cgtgctgaaa ttgggattga ctaaatccta gaaaactaga
    20221 tgaaaataaa aaattatggt acaatagctt ataatattgt agccgatgga gaaagacatg
    20281 aatcttaaac gtgaacaaga atttgttagt cagtatcatt ttgatgcgcg taattttgaa
    20341 tgggaaaatg aaaatggagc tcctgaaacc aaggtggatg tgaatttcca attgctccaa
    20401 catgaccaag aaaatcaagt gacttccttg attgtcatct tgagctttat gattgtattt
    20461 gataagtttg tcattagtgg aacaatctca caagtaaacc atatcgatgg ccgtattgtc
    20521 aatgaaccaa atgaattgaa ccaagaagag gtggaaacct tggctcgtcc atgtttgaac
    20581 atgctcaatc gtttgactta cgaagtgact gaaattgcat tagacttacc aggaattaat
    20641 ttggagttct aatatgaaat tagctgtttt cacagattcc tctgcttatc tcagtgcaga
    20701 gatcttgcaa agagaagact tgtttgtctt ggatattcct gtcaatattg atggtgagga
    20761 atatgtcgaa ggcatcaatc tgtctgctga ggaattttac caaaaaatgg ctcaggcttc
    20821 tgaattgcct aagaccagtc aaccaagtat tgccaagtta gatgagatct taacttcgct
    20881 caaagaacaa ggctatacac atgccttggg gcttttccta tcttctggaa tttcaggttt
    20941 ttaccaaaat atccagtata tggtcgatga ctatgagggc ttaaccattg ctttcccaga
    21001 cactttgatt acaagtgctc ccctaggcat catggttgaa agtgtcttta attggcgtga
    21061 tcagggcgat gattttgcca gcattcagga taagctagcc attcaaatca gccgtacgtc
    21121 agcctttatc atggtagatg acttggatca tttggtaaaa ggtggacgcc tttcaaatgg
    21181 ggctgccatt ttgggcaatt tgcttagcat taagccaatc ctttatttta acgatcaagg
    21241 tgtgattgaa gtttacgaaa aagttcgtac tgaaaagaag gccaccaagc gcttaattga
    21301 aattatcaag gaaacaacgg cttcaggtca ataccgggtc attgtcattc atgggaatgc
    21361 tcctgaaaag gctgaagaat tgcgtcagca cttgcttgat tttggcttgg gttcggatgt
    21421 ttcacttgct acatttggta gtgtcattgg aacgcaccta ggagcaggaa gtattgctct
    21481 gggttatatt ccagtgattt agttggcgct tctaggctag ttaagatgcc ttgtatctta
    21541 gaaattgaac acggactacc tgcctcttga aaaaagatgc ctgtcttgcc tttcgtggaa
    21601 agtcagtgcc attccctatt tttcagaggc agctaaggtc ctttgtatct tgataattga
    21661 acacgcctgg aaccctgtgt gaaaaagata gttcttccaa gaagtagaca cttcttgatt
    21721 ggaattccta ttttcacttt gtgttcttac ggactttgta tcttagacag gagtagagat
    21781 gagtattcga gtaattattg ccggttttaa gggaaagatg ggccaggctg cttgtcagat
    21841 ggtattgact gatccagact tggacttggt ggcagttttg gatccttttg agtctgagtc
    21901 agaatggcag ggtattcctg ttttcaagga taaggctgat ttagctggtt ttgaagcgga
    21961 tgtctgggta gattttacta ctccagctgt tgcctacgaa aatacacgtt ttgctcttga
    22021 aaatggcttt gctccagtag ttggaacgac tggtttcacg agtgaagaaa ttgcagagct
    22081 aaaagaattt tctcgtgccc aagacttggg tggcctgatt gcccctaact ttgccttggg
    22141 tgctgtctta ctcatgcaat ttgcgacgca ggctgccaaa tatttcccaa atgtggagat
    22201 tattgagctc catcatgaca agaaaaagga tgctccgagt ggaacagcca ttaaaacagc
    22261 tgagttgatg gcagaggttc gagagtccat tcagcaaggt gcagcagatg aggaagagct
    22321 gattgctggt gctcgtggtg ctgactttga tggtatgcgc atccactcag ttcgtttgcc
    22381 aggcttggta gctcatcagg aagtcatctt tggcaatcag ggagaagggt tgaccctccg
    22441 tcatgactcc tatgatcgca tctccttcat gacaggagtc aatttgggaa ttaaagaagt
    22501 tgtcaagcgt catgagcttg tctatggatt agaacactta ttatgagatt aatgcaaatg
    22561 ccttctgaat ttcagaaggc tttaccagta ttagaaaaaa ttaaagaagc aggctttgag
    22621 gcttattttg ttgggggctc tgttcgagat gcccttctcc atagccctat ccacgatgtg
    22681 gatattgcga cgtcttctta tccagaagag accaagcaga tttttccgcg aacagccgat
    22741 atcggaatcg agcatggaac cgtcttggtc ttagatgggg atgaggagta tgaggtaaca
    22801 acctttcgga cagaggatgt ctatgtggac tatcgcagac ccagtgcggt ttcctttgtg
    22861 cgctcgctag aagaagacct caaacgccgt gatttcacag tcaacgcctt tgccttggat
    22921 gagacaggag aaatcgttga cttgttccat ggtttagaag atttggaaaa gcaagtcttg
    22981 cgagcagttg gagtggctag tgagcgtttc aacgaagatg ctttacggat tatgcgtggt
    23041 ttccgttttc aggctagtct tggttttgca cttgagccag aaacatttaa agctatgaag
    23101 accttgacgc cgcttttgga gaaaatttct gtagagcgta ccttcgtcga gtttgataaa
    23161 ctcttgctgg ctccattttg gagaaggggc ttggcttcca tgattgagag tcaagcttat
    23221 gactatctcc ctgatatggc atctagccag gacaagctca acagactgtt tgatttggag
    23281 actgatttta cttttgaatc ctctgaacaa gcctgggcgg ctttactatg ggctttggag
    23341 attgaaaatg cgcagtcatt tttgaaatct tggaagacct cacgccagtt tgccaagcaa
    23401 gttcaggatt tgctgattat tttggctctg cgtgaaaatg gagaattgag taagcgtgat
    23461 tgttatcgct ttgacttgga tttactttta caggctgaaa atcttcgtca agctcaggga
    23521 aaagaagtca acccacaagt cattaaagaa acctaccaga gcttgactat tcatgataag
    23581 aaagaaatcc aaatcaacgg cggtattttg atcaaggaat atggctatca gccaggccca
    23641 gacttgggag agattttaac agagattgag tttgccattg tcgatggaga attggagaat
    23701 aatcgtgaag ccatccatgc ttacctgagg gagaaaaaat gagtgatttt atcgttgaaa
    23761 aactaagtaa atccgttggt gacaagaccg tttttaggga tatttccttt attatccatg
    23821 acttagacag aattggttta atcggtgtca atgggactgg caagaccacc cttttggacg
    23881 tcctttctgg tgtttctgga tttgatgggg atgtcagtcc tttttcagct aaaaatgatt
    23941 accagattgg ttacttgact caggatcctg attttgatga tagaaagaca gttttggata
    24001 cggttctatc tagtgaactc aaggaaatcc agctcattcg tgagtatgaa ttgattatgc
    24061 tcgactatag tgaggacaag caggcgcgtt tggaacgtgt catggcagag atggactctc
    24121 tccaagcttg ggaaattgag agtcaggtca agaccgttct tagcaaattg ggcattcaag
    24181 acttatctac tcctgttggg gaattgtcag gtggtctgag aagacgggta cagttggcac
    24241 aagtcttact tggcaaccac gaccttttgc ttttggatga gccgaccaac catctggata
    24301 ttgcgattat tgagtggctg accctctttt tgaaaaattc taagaagacc gtccttttta
    24361 tcactcacga tcgttatttc ttagacgctt tgtcaacacg gattttcgag ttggagcgag
    24421 caggcttgac agaatatcag ggcaattacc aggactatgt tcgccttaag gcagaacagg
    24481 acgagcgcga tgcagctcta cttcataaaa aagaacaact ctacaaacaa gaactggcct
    24541 ggatgcgcag acaaccgcag gcacgtgcga ccaagcaaca agctcgtatc aatcgtttcc
    24601 atgatctgaa aaaggaagtt tcaggcagta gtgctgagac agacttgact atgaactttg
    24661 aaaccagtcg gattgggaag aaagtcatcg agtttcagga tgtttccttt gcctatgaaa
    24721 ataagcccat tttgcaaaat tttaatctct tagttcaggc tcaagaccgt attggaattg
    24781 ttggggacaa tggtgttgga aaatcaaccc tacttaacct gattgcagga agtcttgagc
    24841 cgacagcagg acaagttgtg attggggaaa ctgttcgcat cgcctatttc tctcaacaaa
    24901 ttgagggttt ggatgaaagc aagcgtgtga tcaattacct gcaggaagtg gcagaggagg
    24961 tcaagaccag tggtggttct acgacttcca tcgctgagtt gctggagcaa ttcctcttcc
    25021 cacgttcgac gcatgggact ttgattgaga aattgtcagg gggtgagaaa aaacgtcttt
    25081 atctcctcaa actgcttttg gaaaaaccaa atgttcttct tttagacgag ccaaccaatg
    25141 acctagatat tgcaactttg acagtcttag agaatttctt gcaaggtttt gcaggtcccg
    25201 ttttaacagt cagtcacgac cgctatttct tggataaggt agcgaccaag attctcgctt
    25261 ttgaggatgg caagattcgt cctttctttg gtcattacac cgactatctt gatgaaaaag
    25321 cttttgaaac agatatggcc aatcaagtgc aaaaggccga aaaggaaaaa gtggtcaagg
    25381 ttcgagaaga caagaaacgc atgacctacc aagaaaagca ggagtgggca agtattgaag
    25441 gtgatattga aaccttggaa aaacgtatcg ctgctattga agaggaaatg caggctaacg
    25501 gctctgactt tggtaagctg gctactctcc aaaaagaatt ggatgagaaa aatgaagcac
    25561 tccttgaaaa atacgaacgc tatgagtatc tcagtgaatt tgatagttaa gactattcga
    25621 aaatcaaagt gcaaactatg tcggcttcac attgccgact caagtacagc ctgtgactgg
    25681 cttcctaatt tgcactttga tttttattga gtataaaaga atagaaaaat cccgtctcat
    25741 gaaaggattt ctctattctt ttttggtttc ttgatgaaag atattttgcc aggtttcgtg
    25801 gcgacgccag atactggtat ggatgatacc atctaactca tagcagatga gtttggtttt
    25861 ttgactgatg gaagtaattt gaatgtcctt gatagcagaa tttaactctt ttttggtctt
    25921 ataagcctct ttatccatct gctctccatc ttggcgaata tagacaaaat catcagtcaa
    25981 gagttcttct agttggtttc cttggtcaat caattgttca cgcataagca attttttata
    26041 gacattgtct aaaatttcat cctcagggat aggtgctggt tcgatatgga catcggtatc
    26101 aaagacgcca aaacgctcct ccagcataga ctcgacctga tccgcgattt catggctttc
    26161 aaaaacagac aagtcaggat tcatctctag tgtaatatcc aggtagatgt tgctaccgta
    26221 ggtgcgacct ctttgcgatt tgaccttgct gattttggga atttccatga tagccttttg
    26281 gtagtcctcg agcaggcggt cgtcaaagcc atctgaaaga ctaaaggaag actcgatgaa
    26341 gatatcatag gcagtcttca agataaagaa agtgatgatg atagcaacca gtttatccac
    26401 aatcggataa ttaaaactac tagctaggat ggcaatggcg gttccaagtg aggtaacagc
    26461 gtcagaaaga ttgtccttag cagctgcctt cagcgccttg gagttggatt tcttactgag
    26521 gcgagtattg tagagataga ccacaaacat aatcgctgca gaaatgattc ctagagttgc
    26581 accaagagga tcaatgaccg tttcttcccg actgagaatc ttttgaatgg tatctcttag
    26641 aacatcgaaa ccgacataga acatgatgat agaagtgatc aagcttgcca aatcttcaat
    26701 cttccaatga ccaaaacggt ggtcacggtc tgcaggctgg cgcgccatcc gaatcccgat
    26761 taagagggct acatttccaa tgatgtccga tacgttatta aaaccatcgg ccaccaaact
    26821 ggatgaatga aggagatgac cagctgctaa tttggctgca gacaagatca aataggtcga
    26881 aatactgata atggctccac gctcagctaa cttgagattt gagatagatt gcttcattca
    26941 acttcctttc tagtcacata gcattctacc attatactgg ttttcaagga aaaattcaaa
    27001 taaggcagtt tttactcttt gaaaactccc caaaatttgg tataatggta ctactcaagg
    27061 gagtagctgg cagaaacctg tgatagtgtc gtcattccga attttatgct gaaaagtatg
    27121 ctttccggcc ctatcttaaa cagcgagact tgttatgatt aacaggtctc tttttgtttg
    27181 tcgtgaaaag atatgacaga aagagagtct gttttgcaca caatgtcaag gaggagacac
    27241 atgtcaaaag aacaaaaacg ccaagcgttt tatactcaga gccctgaaga ggtcttgcag
    27301 gctgtggatg cgaccgagca aggtttgtca tcaagtgagg cggaaaagcg ccttgccgaa
    27361 tttgggcaca atgaactcga agaaggcgag aaacgatcaa tcttggtcaa attcatcgag
    27421 caatttaagg atttgatgat tatcatccta gttgcggcag caatcttgtc agtcgtgact
    27481 tctggtgggg aagatatcgc agatgccatt atcatcctag ctgtggttat catcaacgct
    27541 gcctttggtg tttaccaaga aggaaaagct gaagaagcta ttgaagccct caaatccatg
    27601 tctagtccag ttgcccgcgt tcttcgtgat ggacacatgg cagagattga ctctaaagaa
    27661 ttggtaccag gcgatatcgt tgcccttgaa gcaggtgacg tggtaccagc ggacctacgt
    27721 ttgatagaag ccaactctct taaaattgaa gaagcagcct tgacaggtga atctgtacca
    27781 gtcgaaaaag acttgtcagt cgagcttgcg acagatgctg gtattggtga ccgtgtcaac
    27841 atggccttcc aaaactcaaa cgtaacctat ggtcgtggga tgggtgttgt tgtcaataca
    27901 ggtatgtaca ctgaagttgg tcatattgct ggtatgcttc aagatgcgga tgagactgat
    27961 acaccactca aacaaaattt gaacaacctt tctaaggtct tgacctatgc tatcttggtc
    28021 attgcccttg ttacttttgt agtgggtgtc ttcattcaag ggaaaaatcc acttggtgag
    28081 ttgttgactt ctgttgccct tgccgttgca gccattccag aaggacttcc tgctatcgtt
    28141 accatcgttc tttctcttgg tactcaagtt ttggccaaac gacattccat cgttcgtaag
    28201 ttgccagcag ttgaaacact tggttcaact gaaatcatcg cttctgataa gactggtacg
    28261 ctgactatga acaagatgac agtcgaaaaa gtcttctacg atgcggttct acatgactca
    28321 gctgatgata ttgaactagg tcttgaaatg ccactacttc gttcagttgt cttggccaat
    28381 gatacgaaaa tcgatgtgga aggtaacttg attggtgacc caaccgaaac agcctttatc
    28441 caatatgcct tggacaaggg ctatgatgtc aaaggtttct tagagaaata tcctcgtgta
    28501 gctgaattgc catttgactc tgaccgtaag ctcatgtcaa cagttcaccc attgccagat
    28561 ggtcgtttcc ttgtagcagt caagggtgcg ccagaccaac tcttaaaacg ttgtcttctt
    28621 cgtgataagg ctggggatat tgctccgatt gatgagaagg ttacaaatct cattcataca
    28681 aacaattctg aaatggctca tcaagccttg cgtgtccttg caggtgctta taagattatc
    28741 gatagtattc cagaaaatct cacttctgaa gagcttgaaa atgatttaat ttttactggt
    28801 ttgattggga tgattgaccc tgaacgtcct gaagccgctg aggctgttcg tgtggctaag
    28861 gaagcgggaa tccgtccaat tatgattaca ggtgaccacc aagacacagc ggaagccatt
    28921 gccaaacgtt tgggaatcat tgacgcaaac gatacagaag gtcacgtttt aactggtgct
    28981 gaactcaatg aactgtcaga tgaagaattt gaaaaagtcg ttggtcaata ctctgtttat
    29041 gcccgtgtgt ctccagaaca caaggttcgt atcgtcaagg cttggcaaaa acaaggtaaa
    29101 gtcgttgcca tgacaggtga tggtgtcaat gacgcgccag ctctgaaaac agccgatatc
    29161 ggtatcggta tgggaatcac tggtacagaa gtttctaagg gggcttctga catgattctt
    29221 gcagatgata actttgcgac tattatcgtc gcagtggaag aaggacgtaa ggtcttctca
    29281 aacattcaaa agactattca gtacctactt tctgctaata ctgctgaagt attaaccatc
    29341 ttcctatcaa ccttgtttgg ttgggatgtc ttgcagccgg ttcatctttt gtggatcaac
    29401 ttggtaacgg ataccttccc agctattgct cttggtgttg aacctgcgga gcctggtgtc
    29461 atgaatcata aaccacgtgg acgcaaggca agcttcttct caggtggtgt tttgagttct
    29521 atcatttatc aaggtgtact ccaagcagct cttgttatga gtgtttatgg ccttgcgatt
    29581 gcttacccag ttcatgtggg tgacaatcat gctattcatg cagatgccct aacgatggcc
    29641 tttgcaaccc ttggtttgat tcagctcttc catgcctaca atgtcaagtc tgtctaccaa
    29701 tccatcttga cagttggccc attcaagtct aagaccttta actggtccat cttggtatcc
    29761 tttatccttc tcatggcaac aatcgttgta gaaccgcttg aaggaatctt ccacgtaacc
    29821 aaactagact tgtcacaatg gggaattgtt atggctggaa gcttttcaat gattatcatc
    29881 gtcgaaatcg ttaagtttat tcaacgcaaa ctcggttttg acaaaaatgc gatttaaggg
    29941 aggtttcgga tgtcagcata tcaattaccg accgtatggc aggatgaagc tagtaatcaa
    30001 ggagctttta cggggctaaa cagaccaaca gcaggtgccc gtttcgaaca aaacttgcca
    30061 aaaggagaac aagcttttca gctttattca ctgagaacac caaatggtgt gaaggttact
    30121 atcttattgg aagaattact agaagctggt tttaaggaag cggcttacga cttgtataag
    30181 attgctatca tggatgggga tcaattcgga tcagactttg tgaagctcaa tccaaattcc
    30241 aagattccag ccttattgga ccagtcaggt actgaagatg taagagtctt tgagtctgct
    30301 catattcttc tttaccttgc tgagaaattt ggagcctttt taccaagtaa tcctgtggaa
    30361 aaggtagaag ttttgaattg gctattctgg caagcaggtg cagcaccttt tctaggtggg
    30421 ggatttggac atttcttcaa ttatgctcct gaaaaattgg aatatcctat taaccgtttt
    30481 acgatggaag tgaaacgcca gttggattta ttggataagg aattggctca gaaaccttat
    30541 attgcaggca atgactatac gattgcagat attgctatct ggtcttggta tggacagtta
    30601 gttcaaggaa atctttacca aggttctgca aaattcttgg atgcctcaag ttatcaaaat
    30661 ctagtaaaat gggcagaaaa aattgccaat cgtccagctg ttaagcgtgg cttggaagta
    30721 acttatacag aaattaaata gcaaaaaagt catcttcgga tggctttttg ctacagttga
    30781 gggaaagggt ttgcagttat cggcttttgt gctataattg ctataatata gtaaaaagca
    30841 agaggagtgt gaggaagtgg aaaagaaaat tgtgaaggat atcttatttt tatctcaagt
    30901 gtctcagccg gcaagtcagg aggaccttta tcttgccaga gatttgcagg atacactctt
    30961 agcaaatcgt gatacctgtg ttggtctagc tgccaatatg attggggtgc agaagcgcgt
    31021 gattatcttt aatcttggct tggttcccgt ggtcatgttt aacccagtgc ttctgtcctt
    31081 tgaaggatct tatgaggcag aagaaggctg tttgtccttg gtaggtgtga gatcaactaa
    31141 gcgttatgaa accataaggc ttgcctatcg tgacagcaag tggcaggaac agaccattac
    31201 cttgacaggc ttcccagctc agatttgcca gcatgagctg gatcacttgg aaggacgaat
    31261 tatttaggag gaaagcaaat gaaacgaata gtctttgaac ttatttttat cgcaacgacc
    31321 tggtatatct ttttaccgcc ccttaacctg accagctggg aatttctctt cttcctctgt
    31381 gggcatttgt tagttgtggc aatcttattt ggctttggca aggggataaa ccttgtcaaa
    31441 acggttcatg tgcgccacgg taaggcggaa gctgccttaa atcttgaggg tttcaaaatc
    31501 aatcggttag ggaaaattct gttagcttcg attggaggaa ttcttctctt ggcagctttg
    31561 gtttccttgg taacttctag catgtttcag gctaaaaatt atgccaatgt agtcacggtt
    31621 acggaaaaag actttactga atttcctaag agtgacacca gtaaggttcc tatcctagat
    31681 agaagtactg ctgaaaaaat tggagaccgc tacttgggtt ccctaaccga taaggtgtcg
    31741 caatacgtag cggcagatac ctatacccaa ttgacaattg atgggaaacc ttatcgggtc
    31801 acaccactag aatatgcaga ccctatcaaa tggtttaaca atcaagccaa gggaattggt
    31861 gagtatatca aggtggacat ggtaactgga aatgcggatt tggtggactt gaagacacca
    31921 atcaagtatt cagactcgga gtattttaac cgtgatgtca aacgtcacct gcgcttgaag
    31981 tacccgacca aaatctttaa aactccatct tttgaggtgg acgatgaggg caatcctttc
    32041 tatgtagcaa cggtttacca aaagcaattt ggacttgctg ttcctcgtcc tgcttcagtc
    32101 attatcttgg atgctacaaa tggagaaacc aaggaataca gcttatcaga tgttccagaa
    32161 tgggtggaca ggatctatcc agcagaggaa accattgagc aaattaacta caacggcaag
    32221 tacaaggacg gtttcttgaa tgccatgatt tccaagaaaa acgtgaccca gactaccaag
    32281 ggctataatt acttgtctat cggtaatgac atctatctct acacaggtgt gacgtcggct
    32341 aatgcggatg agagtaatct tggtttcatc cttgaaaata tgcgaacagg agaaatcact
    32401 aagtatagct tggcttctgc gacagaagaa tcagcccgtg aatcagcaga aggtgctgtt
    32461 caggagaaat cctacaaagc aaccttccca atcctcatca acctcaatga caagcctctc
    32521 tacatcatgg gcttaaagga caatgctggc ttggtcaaag agtacgccct ggtagacgca
    32581 gtcgagtacc aaaatgttat cgttgctact acagtggaag agatgctcag caagtatgcc
    32641 aataaaaacg accttgaaat tgacaatgca acgacagaaa gcatcaaggg agtagtagca
    32701 gacctcaaat cagctgttat caagggcgac accgtctact tctttaaagt tgatggcaag
    32761 atttacaagg ttaaggcctc agtatccgat gaccttcctt accttgaaaa tggtagaacc
    32821 ttcgaaggtc aagtaggaaa agacagctat ctcaagacct ttaaagtaca gtaatactct
    32881 gcgaaaatct cttcaaacca cgtcaacttt atctgcaacc tcaaagctgt gctttgagca
    32941 acctgcggct agtttcctag tttgctcttt gattttcatt gagtataaaa aaggtttatt
    33001 taagaaatat atgttatagt aaaataaatt aagactaatg gaggacaaag aaatgggttt
    33061 ttatttgatg gttgcttcaa tgctactcgg actgctcgct ttgaagatag gtttttctca
    33121 gttcaaggag aacaaagata aattcttatc tatcttaaca agtttagctg ggctagccct
    33181 tgttctcgtg gctgtctggt taggatggcc caaataaata gaaaaacctc ggtcaaaccg
    33241 aggtttttca gatgaatttc ttggttgtgg ctaaaaaata tgctacacta tcaatatgaa
    33301 gattttaatc cctacagcaa aagaaatgaa tacagacttg ccgagtatcg agacaactct
    33361 tttaagatca gaaagtcagg ctgtacttga tgccttggct ctctattctg ccagtcaatt
    33421 ggaaagtttc tacaaggtat cagctgagaa ggctgcggaa gaatgtcaaa atatccaagc
    33481 tttgaaaagg caaactgttc aacactaccc agccttgaag ctttttgatg ggcttatgta
    33541 ccgtcatatc aagagagaca aactgaccga ggtagaacaa gcctatcttg aaaatcatgt
    33601 cttcattacc tcggctttgt acggagtcgt tccagccttg tcgcctatgg cacctcaccg
    33661 tttggatttt ttgatgaaat taaaagtcgc tggtaagact ttgaagagcc attggaaggc
    33721 agcctatgat gaagctgtga agcaggaaga agtgattttc tctctcttgt catcagagtt
    33781 tgagactgta ttttctaagg aaatcagagc aaagatggtg accttcaaat tcatggagga
    33841 tagaggcggt cagctgaaga ttcactcaac tatctccaag aaagcgcgcg gggcctttct
    33901 aacagcttta atagaaaatc aagtacaaac tgtgggggaa gcacgtcgct tgaactttgc
    33961 tggatttgtt taccgagaag atttgtcaca accacaggga ttggtttttg taaaggaagt
    34021 atagaaatca gataagagaa aagtcagcac gattatgctg acttttttga taacttataa
    34081 agtattggac aaatgaatct catttgataa ggtgttaaga tgattaacca aattcatgat
    34141 tgacagatga tttcggcaaa taaacttctt ggtaatccct gaaatataga aattagacac
    34201 gatgatatcg taatctgtct gatttaaaat ctcaggactt gtttttaatt catcccaaat
    34261 atcgaaggta aagcggttat tacagtaata ggaaagcata tcaacaaagg taagggatat
    34321 agcatggtca aagttactga taatcaaaac cttgataggt ggtcgatttt ctaacaactg
    34381 agtagagagg ttttcagcat gggttaagat ggtgtacatc aagtgttcca actgttcagg
    34441 atggtcatgc tgtccaattg cctgacggta ttgagccagt tcttgacgcg cacttcccat
    34501 aaagtctggg aagtaaactt caaatttttt aatcgtcaat gctttttgtt caaataagat
    34561 tggggtagaa aagatttcct gtctttcaaa gaaagcagtg ttgtgtaaat gccaaatcag
    34621 ctcatcgtgg ttagtaaaag taatcttata ttgttttgat aggcgttcta atatttgact
    34681 aagtaattgg taagagtatc ttgcttgact gttatcttct aaagagttga agaattcttg
    34741 aggatctagg aaaatatcat tctgaagaaa agaaataaaa atttgagcga ttgtatctgg
    34801 agtcatttca agcccaaaat gtttagagaa ataagcaagt gtctcctgga aatttggaat
    34861 gctctttaaa agaggataat attctttgta aaagtggttg gggaggtcaa tgaagtgacc
    34921 atttttaacc ctgtggatac tgatagctat catcagtttg tacattctat aaattgaaaa
    34981 tcgcattgga taattcgtga ttttatagaa gaagtcagca aactctgtta aatcttcctc
    35041 aggaaggtca ggaaaaggcc aatctaggaa ataatagcgc tcagaaaagt attgggcaaa
    35101 aaagtaacga atatcgatct catttccacg tatctcggat ggagtaaaag ataattcaat
    35161 ttgaaactga gatgaaagaa cctttgtaat atttctgccc agtcgataga ggttggcact
    35221 actaaagtaa agattttcta ttgttcgata aataggtagc ccctcattga agaacatata
    35281 ctctagtaat tgaaaagatt gagaattagc aagaaaatat tgataaatat cttctacact
    35341 agtgttaact tctaaatcta tcatgattcc gttaacagaa gattggatgt taatagatgg
    35401 aaaggcaata cgtaattcat ttaaatcact ttttaagatt cgttctgtac atcctaattt
    35461 ttcggctagt tcatgtaatt tcatccaatt acgattctga attagggttt ccattaagcg
    35521 taattgtctt tgaacttttg tggataaaag gtttctcata cgggtatttc ctccataatt
    35581 cattatatct ttttttgtct aagtagtata aaaaaattag agcaagaaaa ttgtcgttag
    35641 taatcggaaa aattagaata atataagtgg cttttaagtg caaaaacaga atatattaat
    35701 tgttcagaaa atattgatta atgcctcaaa tagttgtaca ttgtaaacta taaaatacta
    35761 tctaggagtt taaaatgaaa cattcacata aaaaatcatt tgactggtat agcatgcaac
    35821 aacgttattc tattcgtaag tattactttg gtgcagttag tgtcttgctc ggtaccgctt
    35881 tggtattagg tgcagcagct agtgtccaaa cagtacaagc ggaagaaaac aaacaagaaa
    35941 ctaccaatag tatttctgtt ggtaggggag aagcagctac taaaccagca gaggtttctg
    36001 cgtctaataa agagaaaacc tatgcagctc caactgtagc taatccagta gaaacgactc
    36061 cagttaaaac tggagaagtt actaaaccag cagaaaaagt tgaagaagca aaagacaaaa
    36121 aagaggaagt aacgcatcaa gatgctattg acaagtcaaa attgttaacg gctctttcgc
    36181 gtgctaaaaa gttagaaagc aagttatata cagaagcaag tgctgctaac ttgcaaacaa
    36241 gtatccaagc tggtcaaagc ttgcttggga aagcagatgc atctgaagct gaattatcag
    36301 cagcagagtc atctattcaa tcatctatta ttggtctaga acttcgttct aactctaaca
    36361 aaggaactgt atcagaaacg cctgtagcaa agaaagctaa tatagttgaa gcgaaggaag
    36421 agactaaacc agctgtaaca acgactgaac gttcagctgt tgatagcgct attttgccaa
    36481 ttagcacagc tgctaaagta gaaacaactt cagctccagc atctactaat gaaatcttga
    36541 aaccaagttt gagcctttct gatgctcgcc aaaatccagc tatccgtaag gaagatgttg
    36601 atagagggta tagtggtttt agaacagcag gaagtggctt tagagcggct ggaagtggtt
    36661 ttagagcagc tggaccagaa aataaaccaa tcttaaatcc aaataatact attgcatttt
    36721 ctgacatcag tcagggctta cattcatttc gtggtatagg acattcacgt ggtggtcgtg
    36781 aaatccatta tgatgtaacg acagtacgta gaggtaatag attgaatttc acaattaaat
    36841 actctggtcc aggtgaattt gttaataata attttatctt ggataaaggg gatggatttg
    36901 gaaatccttc aaatgcaacg atcacaagtt caaatccaag agtaagggag caatcaaaat
    36961 ctattagtca gggtgccaac tacgtatctc actcaggata cagtatgacc tctgctactt
    37021 caacaaatac ggaacaaact atcagattta gtttgcctat cattaatcca aatggtgatt
    37081 tgtctgttcg tttgaaacca gttactttta acgtggacca aggtggtggt ggtgccgcta
    37141 ctagcaatga cccatacagt aactccaact attatcatag agcaaatcca ctcctcttgg
    37201 atgcaaaccc ttatggtggt actaataata agactgtttc agaagacatt gacttccaaa
    37261 ctgtctatct tccaactagt aagttaccag aaggtcaaac tagattagtt cgagaaggtg
    37321 aaaaaggaca acgtcaaatt acctataaag tacatcgatt tggtaacgaa acacttttag
    37381 gattgccaat tagtaataga gttactaaag aagctaagcc acgtattatg caaattggtg
    37441 tggctaaaga gttaatcgat acagtaaaac cacgtgttga tcaaaataaa gttggtgata
    37501 caaataacct cactttctat cttgataacg atggaaacgg tgtttatact gagggcgtag
    37561 acgaacttgt tcaaaaaatt gctattaaag atggagccaa gggtgaaaaa ggggaccaag
    37621 gtgaacgcgg tctaaccgga gcgcaaggta ctaaaggtga aaagggagat cagggtgaac
    37681 gcggtctaac cggagcccaa ggagctaaag gtgaaaaagg tgaacaaggt cttcaagggc
    37741 gtgatggtga acaaggacca aaaggagaag atgggaaaac cccaacagtt aaagtaactg
    37801 atggtcaaga tggaacgcat acaattacaa ttaacgatgg taaaggtggt ataactacta
    37861 cagtagtaag agatggattt gatggtgcaa gccctcttgt ttctactcat agaaatgaag
    37921 cagataaaac aacaactgtt attttctatt atgatctaaa tgataataat caatttgatg
    37981 aaggagatac aaaacttaaa gaagttgtta tcgcagatgg aaaacaagga ccaaaaggtg
    38041 acaaaggtga taacggaaaa gatggattca caccagaagt aacagttaca gataacaata
    38101 acggaacaca caccatcaca atcacacaac cagacaacag accatcatta acaacaatcg
    38161 ttaaaaacgg tgaagatgga aaaacaccaa aagtcaaagc agaacgagat gatgcgaaga
    38221 aacaaacaac attaacattc tacattgaca aagatggaga tggaagttac acagcaggaa
    38281 aagacgagtt agttcaaaca acagtagtta aagacggaca agacggagct gcaggagcat
    38341 ctggacgtga tggaaaagaa gtattaaacg gaaaagcaga cccaacaaca gaaggtaaag
    38401 atggagacac attcgtaaat acacaaacag gagatgtatt cgttaagaaa ggtaacactt
    38461 gggaaccagc aggaaacatc aaaggaccga aaggtgacaa aggtgcagat ggtgctaaag
    38521 gcgaaaaagg agaccgaggc gaacgcggtc taaccggagc gcaaggtact aaaggtgaaa
    38581 agggagatca gggtgaacgc ggtctaaccg gagcgcaagg tactaaaggt gaaaaaggag
    38641 accgaggcga acgcggtcta actggagcgc aaggtcaggc aggtcgtgac gctgtaactc
    38701 caaccgtaac cgttaaagat aataaaaatg acggcactca tactatcact attaacgacg
    38761 gtagaggtaa tgttgcaagt actgttgtaa gagatggttt cgatggcgca agtccattag
    38821 ttgcgactca acgaaatgaa gcagataaga caacaactgt tatcttctat tatgatcaaa
    38881 atggaaataa tgaattagat gcttctgata agaaattaaa agaagttatt attgcagatg
    38941 gtgccaaagg tgaacaaggt cttcaaggtc gtgatggtca agacggagct cagggacaag
    39001 caggacgcga cggtaaagac gtgttgaacg gcaaagctaa tccagaagta aatcaaggta
    39061 aagacggtga taaatacgtc aatacagaaa caggcgacgt cttcgttaag aataacggca
    39121 actgggataa agagggcaac atcaagggac ctaaagggga caaaggtgaa cgcggagaag
    39181 atggtaagac tccagaagta actgtaactc caggtaaaga tggccatagt actgacatta
    39241 cattcactgt tccaggtaaa gatccagtaa ccttcactgt aaaagatggt aagaatggta
    39301 aagatggccg tgcaccgaaa atcaaagtag aagatattac ttcaccttca agaattagac
    39361 gcgatacaga tgctgctgca actccaacgc gtaacggtat ccgtgttaca gtttatgatg
    39421 atgttaatga caatggggta tacgacgaag gtgtcgataa agtattaaat agtaaagata
    39481 tttataacgg tatagatgga cgtgatggtt cagctccaac tattactaca aaagataatg
    39541 gagatggaac tcacactatc acagttcaaa acccagatag ttctgaatca acaacagttg
    39601 ttaaagatgg taaagacggt aaaactgcga atatcactac aacagaaaac ccagatggaa
    39661 gccacacaat tacggtgaca aatccagatg gttcaactaa agaaactgtt gttaaaaacg
    39721 gtaaagacgg taagactcct aaagttgaag taacggataa caacgatgga actcatactg
    39781 ttaaagttac agatggagac ggcaatgtta ccaacgctat catcaaagat ggtaaagacg
    39841 gtaaagctgc aacagcaaca actactgaaa atccagatgg aagccacaca gtaacaatca
    39901 ctaacccaga cggaactaag aatgagtttg ttgttaagaa tggacgtgac ggtgttgacg
    39961 gacgtactcc aaccgcatct gttcgtgata atggagacgg aagtcataca atcgttatta
    40021 caaatccaga aggtgtgaca actgaaacca cagttcgtga tggtaaatca ccaaaagtga
    40081 ctataactga tgaacaaaat ggaactcata agatctctgt tctaaatggt gacggaacaa
    40141 ctactgaaac aatcattaaa gatggtaaat caccagtagc aacagttaga gataaccaag
    40201 atggtactta cactattcgt gtggaaaacg gtaatggtac tgtttctgaa accacagttc
    40261 gtgacggtaa atcaccaact gctaaggttg tggataatgg agatggaact cacactatca
    40321 cagttgtgaa ctcagacgga acaactacaa caactacagt tcgtgatggt agagaaccaa
    40381 aacttgaagt tattgataac aacgatggtt cacacactat taaagtgaca ggtgctgatg
    40441 gtaaaggaac gacaactaca atctttgatg gtaaatcacc aaaagcgaac atcgttgata
    40501 acggagatgg aactcataca ttaacaatcg tagattctga tggtcgtgaa tacaaatcta
    40561 ttatcaaaga tggtaaagac ggcaaagata gcgtttcacc aactgtaact gttaaaaata
    40621 ataacgatgg aactcacgtt gttacaatca ctaatccaga tggaagtaag acagaaatgg
    40681 tgattaaaga cggtaaagat ggaaaatgtg gatgccaaga caaaccagta acaccatcaa
    40741 atgacaaacc agttcctcca acaccaaatg tgccgacacc agaagtaccg gttaaacctg
    40801 tgccagcgca accaacacca aatgtaccga caccagaagt gccagtacaa ccaactccag
    40861 ctgttccaac accagaagta ccggttaaac cagtaccagc ggttccagaa caaccagtag
    40921 taccaacacc ggctcaacca gcaactccag taaatgctaa tccagtagca ccaactacag
    40981 gtaaagaaaa ccgtggggac aaattacctg aaactggaag ccaatctgat tatatctctg
    41041 ttcttttagg tagcggtatt ctattgagcc tatatgtagg acgaagaaaa gaagattaat
    41101 cagccaaaag cagtcactaa tttctcgaaa gaagatgata agtgatagat ctcgaatgaa
    41161 agaatattct tagaatgatt ttcctatgat ggaaaagact gctaaaaacc ttgagtggta
    41221 acgctcaagg tttttttgga tggctgatgt ttgtctgaaa atcttgattg agaaataaaa
    41281 agccacccta ttaggtggct ataattgatt tagactttct aaaattttct attttttact
    41341 gaatcgcttc gaccaagtct tgagcttgtt tttcaagtga gtttaggact gtttcttcaa
    41401 gaaccaattt tccgtctgcc caggcagagt cattaacacg tgcagcagtg aaatcaccaa
    41461 cgccttgtgt acggataaat ggcaagaggt ctttgtagat agcgaaaagt tgatcgtgcc
    41521 ctgcattggc tacagatgat actgtgacaa acttgtcttg aagggcagaa acgccacgtg
    41581 tatcagacaa gtcaagggca cgagatagcc agtcaagcaa gtttttcact gtaccaggga
    41641 tagagaagtt gtagactgga gagaaaatcc agatagcatc cgcaacgaga actgcttcac
    41701 gagcagcagc tacagctgga tgtgttggaa cttccaaatc ttggctgaag agaggaaggg
    41761 ctgaataatc aaggtagcta acttccgctt taccagcaag tgctttctca gcttcgagcg
    41821 ccatttggtg gttgaaagaa ccttgacgta gtgatccgac gataaataat acttttttag
    41881 acatgatgtg tctccttttt cttaaaattt cgagaactct ctcgttgtta taaaatatat
    41941 tacaacaaaa caaaagaact tgcaagaaat ttgctcagag tttatttgaa aattgtaaaa
    42001 tttcggaaac tctaatcatt tgtgactgaa aaagtaagaa ctgtttcact ttcaaaatcg
    42061 gttttgtttg aagggagaaa tagaattggt tgctcaaagc acagctttga ggttgcagat
    42121 aaagctgacg tggtttgaag agattttcga agagtattct tatattcact tgtaataaag
    42181 cttaatagat ggtaaaatag acgagtgaaa aaaagacaaa acaaagcaaa aaataatcta
    42241 ctgtggcagt atggtctagg gatgacgatt ttgtttgtgg ttatcagtgg ttcctttctg
    42301 tatatggttt ctcttagcat gaaaccctat caaacagcta aaagtgaagg agaaaaatta
    42361 gctcagcagt atgcaggatt agagcaggtc gatcaggttg atttatacaa tggcttggaa
    42421 tcttattaca gcgttcttgg tcgtaataaa cagcaagaag cgcttgctgt cctgattggt
    42481 aaagatgacc ataagattta cgtttatcag ctaaatcagg gtgtttcaca agaaaaagca
    42541 gaaacggttt ctaaggaaaa gggagctggc gagattgaca agataacctt tggccgttat
    42601 caagataagc caatctggga agttaagtca ggatctgatt tttatctagt agattttgaa
    42661 acaggagcat tggtcaacaa ggagggccta tgaaactatc caaccgtgtt ttagaaatgg
    42721 aagaaagtgt gactttggct gctggagccc gtgccaaagc actgaaggct gagggtagag
    42781 atattttgtc tctaaccttg ggtgagccag atttcactac tcccaaaaat atccaagatg
    42841 ccgccattgc atcgattcga gatgggcgtg cttcttttta tacagtaacc tcgggtctgc
    42901 cagagcttaa ggcggcggtc aatagctact ttgagcgctt ttacggctat tctgtagcgt
    42961 caaatcaagt gacagtcgct gcgggagcca aatattctct ctataccttc tttatggctg
    43021 tggtcaatcc aggtgatgaa gtcatcatcc caaccccata ctgggttagc tatggagatc
    43081 aggtcaagat ggcagaaggc gttcccgtct ttgtttctac taaggaagac aatcacttta
    43141 aggtgaccgt agatcagtta gaagcagctc gcactgacaa gaccaaggtt ttggtgctga
    43201 attcgccatc taatcccaca ggtatgattt acacccgtga ggaactcttg gcaattggaa
    43261 actgggctgt agaaaatgat attctcatcc tagcagatga tatctatggc cgcttggttt
    43321 ataatggtca tgagttcaca ccgatttcta gcctatcgga agcgattcgc aagcaaacag
    43381 tggtcatcaa tggtgtgtct aaaacctatg ccatgactgg ttggcggatt ggttatgccg
    43441 ttggagaagc agatattatc gctgccatgt ccaagattgc aggtcaaaca acttcgaatc
    43501 cgtcagcagt agcccaatat gcagcagttg aggctctatc aggtgagcaa gatactgtag
    43561 aaagcatgcg tcaggccttt gaggaacgtc ttaataccat ctatcccctc cttgcagagg
    43621 taccaggatt tgaagtggtc aaaccgcaag gggccttcta tctcttccca aatgtcaaaa
    43681 aggccatgga gatgaaaggc tacacggatg tgacagactt tacaactgct atcttagaag
    43741 aagccgaagt ggccttggta acaggagctg gatttggagc accagaaaat gtccgcctca
    43801 gctatgcgac agacctagac acgcttaaag aagcagtcga acgcttgaaa gcatttatgg
    43861 gtagtgagaa tgattgatca ttttgagatt aaggtaaagg atttacaaat ttcagaagga
    43921 ttttatagga gttttctcgc tcctttggac tataaattgg cttttaagac tagttctcta
    43981 attagttttc tatccccgaa cagccctcat cctggtggtg atttttggct gactcaggga
    44041 acacaagatc ctgttcattt tgctttttta gcagaaaata aggaagaagt tcaggcttgt
    44101 tatgaggctg gcttagaggc aggtgggcga gacaatgggg ctcctggtta tcgaagtgag
    44161 catccgattt actatgctgc ttttatgatt gacctggatg ggaacaatat agaggtggtt
    44221 tgccataaag aataaaaaag aaaaggaaaa ataatgacaa aacgtgtaac gattattgac
    44281 gtaaaagact atgttggtca ggaagtgacg attggcgctt gggttgccaa caaatcagga
    44341 aaaggaaaaa tcgctttctt acaattgcgt gatggaacag ccttctttca aggtgtggct
    44401 tttaaaccaa actttgtcga aaaatttggt gaagaagtgg gacttgagaa gtttgatgtt
    44461 atcaaacgct tgagccaaga aacgtctgtt tatgtgacag gtattgtcaa agaggacgaa
    44521 cgttctaaat ttggctatga gttggacatc acagacatcg aagtgatcgg tgaatctcaa
    44581 gactacccaa tcacaccaaa agaacacgga acagactttt tgatggataa ccgtcacttg
    44641 tggctacgct ctcgtaagca agtagctgtg ttgcaaatcc gtaacgctat tatctatgca
    44701 acttatgagt tctttgacaa gaacggtttt atgaagtttg acagcccaat tctttcagga
    44761 aatgcggcag aagattctac agaactcttt gaaactgact acttcggaac gccagcctac
    44821 ttgagccaat caggtcagct ttacctagaa gcaggggcta tggctcttgg tcgtgtcttt
    44881 gactttggtc cagttttccg tgctgaaaaa tcaaaaacac gccgtcactt gactgagttc
    44941 tggatgatgg atgctgagta ctcatacttg acacatgatg agtcgcttga cttgcaagaa
    45001 gcttatgtga aagctcttct acaaggtgtt cttgaccgcg cgcctcaagc cttggaaacc
    45061 ttggaacgtg atacagaact cttgaaacgc tacattgcag agccattcaa acgtatcact
    45121 tacgatcaag ccattgacct cttgcaagag catgaaaatg atgaagatgc tgactacgag
    45181 catcttgagc atggtgatga ctttgggtca ccacacgaaa cttggatttc aaaccacttt
    45241 ggtgtgccaa catttgtcat gaactatcca gcagccatca aggccttcta catgaaacca
    45301 gttcctggaa atccagagcg cgtgctttgt gcagacttgc ttgctccaga aggctatgga
    45361 gaaattatcg gtgggtctat gcgtgaggaa gattacgatg cccttgtcgc taagatggat
    45421 gaacttggca tggatcgtac agaatatgaa ttctaccttg accttcgtaa atacggtaca
    45481 gttccacacg gaggatttgg tatcggtatc gaacgtatgg taaccttcgc agcaggaaca
    45541 aaacatatcc gtgaagctat tccattccca cgtatgttgc accgtatcaa accataagaa
    45601 caggaaaacg cccatgtggc gttttttcga attctagtgt ttttacttgc gtaaaaaaat
    45661 tttttctagt ataatagttt attgtgagcg aacctcactt accccttgca aagtcttggg
    45721 gtcattagac caaaaggagg aacatatcaa tggctaaata cgaaattctt tatatcattc
    45781 gtccaaacat tgaagaagaa gctaaaaacg ctttggtagc acgttttgac tctattttga
    45841 ctgacaacgg tgcaactgtt gttgaatcaa aaacttggga aaaacgtcgt cttgcatacg
    45901 aaatccaaga tttccgtgaa ggactttacc acatcgttaa cgttgaagca aatgacgatg
    45961 cagctcttaa agagtttgac cgtctttcaa aaatcaacgc tgacattctt cgtcacatga
    46021 tcgtcaaaat tgacgcgtaa gaaggtaaac tatgattaac aatgttgtac ttgtagggcg
    46081 tatgacacgt gacgctgagt tgcgttatac cccatcaaat gtagcagttg cgacttttac
    46141 tcttgcagta aaccgtacat ttaagagtca aaatggtgaa cgtgaggctg attttatcaa
    46201 tgtcgttatg tggcgccaac aggctgaaaa tcttgctaac tgggctaaaa aaggctcact
    46261 tatcggggtg acaggtcgta tccagactcg tagttacgat aaccagcaag gacaacgtgt
    46321 ctacgtgaca gaggtcgtgg ctgagaattt ccaaatgttg gaaagccgta gtgtgcgtga
    46381 gggccacaca ggtggagctt actctgcacc aactgcaaac tattcagcac ctacaaattc
    46441 agtaccagac ttttcacgta atgaaaatcc atttggagca acaaacccat tggatatttc
    46501 agatgatgat ttaccattct aatggacaac taaacttata aaggagaaaa aacatggctc
    46561 aacaacgtcg tggcggattc aaacgccgta aaaaagttga ttacatcgca gcaaacaaaa
    46621 ttgaatatgt tgattacaaa gatactgagc ttcttagccg tttcgtttca gaacgtggga
    46681 aaatccttcc tcgtcgtgta acaggaactt cagctaaaaa ccaacgtaaa gtaacaacag
    46741 ctatcaaacg cgctcgcgta atggctttga tgcctttcgt aaacgaagat taaagaaaag
    46801 acccggttgg gtctcttttt catgagcttg aaaacaagaa agcgaattaa gaccccaacg
    46861 ggtctttttt cacaagcttt gaaatgagag agcgagttag gctcagtggc tcccttttta
    46921 cgagtttgaa aacaagagaa cacattaaaa gcacgatgga gctttttcat aaatatgtct
    46981 tttttctcat ccaagaaatt aaaataaaaa tgataaactt tttgaaaata ggggatttgc
    47041 ctactttatg atataatgga aagagttaga ttgaaagagg tagtgagatg gacgcgaaat
    47101 taagatacaa ggcaaagaag atcaagattg tcttttttga tattgatgat acattgcgga
    47161 attcaaagac agggtttatt ccaactacaa ttcccactgt ttttaaacag ttgcgtgaaa
    47221 aaggaatttt aacaggaatc gcctctggac gtggcatttt tggtgttgtt ccagagattc
    47281 gtgatctcaa gcctgacttt tttgtaactt tgaatggagc ttatatcgaa gataaaaaag
    47341 gtcaggtcat ttatcagcat cagattgaaa agtcagatgt tgaggagtat atctcttggg
    47401 ctaagcaaga aggaattgag tatggcttgg ttgggagtca tgatgccaag ttgtcgactc
    47461 gcaccgatat gatgagtgaa gctatcaatc caatttatcc cgacttagat gtagatcccg
    47521 atttccatga aaaagaagat atctatcaga tgtggacttt tgaagataag ggagatgact
    47581 tgcacttgcc tgacagtctc tcagacaaac ttcgcatggt tcgttggcat caacattcgt
    47641 ctgatattgt gccgatttca ggctccaaag cgacgggggt ggaaaaggtt gtggaacacc
    47701 ttggcttgaa accagagaag gtcatggttt ttggagatgg tctcaacgac ttggaactct
    47761 ttgattatgc tggaatcagc gttgccatgg gaatttctca tgataaaatc aaagaaaaag
    47821 cagattatat tacaaaaaca ttagaagaag atggcatttt tgatgcctta gaagtatttg
    47881 gtatggtaga aaaagaattg cattttccac aagtagacat tgaaacagta gaaggtcctc
    47941 ttgcgactat taagaccaat cacggagact tacgtatcaa gcttttccct gaacatgctc
    48001 ctaaaacagt ggctaacttt gtatctcttt caaaagatgg ctactatgat ggtgtcattt
    48061 tccaccgtat tatcaaggac tttatgatcc aaggtggaga cccaactgga actggtatgg
    48121 gtggcgagtc aatctacggc gaatcttttg aggatgaatt ctcagaagag ctttacaata
    48181 tccgtggtgc tctttccatg gcaaatgctg gtccaaatac caacggcagc cagttcttta
    48241 tcgtgcaaaa ccaacaccta ccttattcga agaaagaaat tactcgtggt ggttggccag
    48301 aaccgattgc agaaatctat gccaatcaag gtgggacacc tcacctagac cgccgtcaca
    48361 cggtttttgg tcagttagct gatgaagcat cttacgctgt cttggatgcc attgctgctg
    48421 ttgagacagg agctatggac aagccagttg aagatgttgt aattgaaact attgaaatcg
    48481 aggactaaga tgaaaatcgg tgataagcta aaggggcgta ttacagggat tcagccctac
    48541 ggtgcctttg ttgagttaga gacgggtgat acggggctga ttcacatttc agaaattcgg
    48601 acaggattta ttgaaaatat tcatgaaacc ttgaaagtcg atgaagaggt tcaagttcag
    48661 gtagtggatt tagatgaatt tacggggaaa gccagtcttt ctatccgcac tttggaggaa
    48721 gaaaagtacc agtttcctag acggagacgc ttttcaagcg accgctttaa ctacggtttt
    48781 gctccctttc gacgaatgct accaatctgg actggagaag ccctgcacca tttaaaaaag
    48841 aagaagtagt ttagagtttt atattttttg taatgttaat atgaatttgc tataatagga
    48901 ccatggaaga agaacaatta ttaaaatcag gagagcgcat taaccagctc ttttcgacag
    48961 atatcaaaat cattcaaaat agagaggttt ttagctattc ggtggatagt gttctcttat
    49021 cacgatttcc acgttttcct aagaaggggt tgattgtgga tttctgtgct gggaatggag
    49081 cagtggggct ttttgctagc actcgtactc aagcacagat attgtctgtt gagattcagg
    49141 agcgtttggc ggatatggct gaacgctctg tccgtttgaa tggattagag gagcaaatgc
    49201 aggtcatctg cgatgatttg aaaaatatgc ctgctcacat tcaggggagt aaggtggata
    49261 tgattttgtg taatccaccc tatttcaagg tgaatcctta ttctaatctg aacgagagtg
    49321 aacattatct cttggctcga cacgaaatca cgactaattt ggaagaaatc tgtcgtagtg
    49381 cccagagtat tctcaagtct aatgggcgtt tggccatggt tcatcgtcct gatcgacttc
    49441 tggatatttt ggatacgtta aaacgacata atctagcccc taagcgcctg cagtttgttt
    49501 atccaaaaag agaaaaggaa gccaatatgc ttttgattga ggcgatcaag gatggctcaa
    49561 caagtggctt taaggtctta cctcctttga ttgtccacaa tgatgatggc tcttatacgc
    49621 ccgaaatcga agagatttat tatggatcat aaggcttata tgtacgttct ggagtgtcgt
    49681 gatggatcct actatatagg ctatacgact gatatgagaa gacgcctcgc tatccacaat
    49741 agtgggaagg gagccaaata tacacgagca cgcttgccag tcaaacttat ctatgctcaa
    49801 ggttttgcca gtaaggaaga agccatgtcg gctgaagctc ttctcaagcg taagaagagg
    49861 ccacagaagg aagaattttt atctgaaaat caagatagaa atttactcag ttattttgaa
    49921 gaatcgtggg gagtcctttg actcctctta cctttgtcaa aaagcgaaaa aaatgctaca
    49981 ataaagaaaa taaacaaaat gaggtattat catgtccaag attctagtat ttggtcacca
    50041 aaatccagac tcagatgcca tcggatcatc tgtagctttt gcctaccttg caaaagaagc
    50101 ttacggtttg gatacggaag ctgttgccct tggaactcca aatgaagaaa cagcctttgt
    50161 cttgaactat tttggtgtgg aagcaccacg tgttatcact tctgccaaag cagagggggc
    50221 agagcaagtt atcttgactg accacaatga attccaacaa tctgtatcag atatcgctga
    50281 agtagaagtt tacggtgttg tagaccacca ccgtgtggct aactttgaaa ctgcaagccc
    50341 actttacatg cgtttggagc cagttggatc agcgtcttca atcgtttacc gtatgttcaa
    50401 agaacatggt gtagctgtgc ctaaagagat tgcaggtttg atgctttcag gtttgatttc
    50461 agataccctt cttttgaaat caccaacaac acacccaaca gataaaatca ttgctcctga
    50521 attggctgaa ttggctggtg tgaacttgga agaatatggt ttggcaatgt tgaaagctgg
    50581 taccaacttg gctagcaaat ctgctgaaga attgattgat atcgatgcta agacttttga
    50641 actcaacgga aataatgtcc gtgttgccca agtgaacaca gttgacatcg ctgaagtttt
    50701 ggaacgccaa gcagaaattg aagctgcaat gcaagctgcc aacgaatcaa acggctactc
    50761 tgactttgtc ttgatgatta cagatatcgt caactcaaac tcagaaatct tggctcttgg
    50821 tgccaatatg tacaaggtcg aagcggcttt caacttcaaa cttgaaaaca atcatgcctt
    50881 ccttgctggt gccgtttcac gtaagaaaca agtggtacct caattgactg aaagctttaa
    50941 tgcgtaagat tttgggtgtc agctcaaaat cggaaagtct agtttgcctt atatcgaaag
    51001 gagtttcggc tccttttttc taggagtgaa gtatgttaga aaatggcgat ttgatttttg
    51061 tgagagatgg gtcagacatg ggacaggcca tccagacttc cacaggtaac tatagccatg
    51121 ttgccattta tttggatggg atgatttatc atgctagtgg acaggctggt gttgtctgtc
    51181 aagaaccggc agacttcttt gagtccaatc atttatacga cctctatgtt tacccagaaa
    51241 tggatatcca gtcggtgaag gaaagagctt gcaaacatct tggagcaccc tacaatgctt
    51301 ctttctatcc agatgcacct ggtttctact gctcccagta tatagcagaa atcctaccta
    51361 tttttgaaac tattcctatg aaatttggag atggggagca ggagattagt gatttttgga
    51421 gggagtatta catagaacta ggtctgcctg ttcctctgaa ccaagctggt accaatccta
    51481 gtcagttggc agcatcgcct ctgttacaat gtaaagaaag gaatcttcat gattcagatt
    51541 tttaatccat ctcgtttgac gagacagcca tttttggaga attgatccgc tatctggacc
    51601 agtatgagga tgtgattcta cgggaaatta aggctcaatt tccagatgtt gcagttgata
    51661 aactcatgga agagtatata aaggcaggct tgattctacg tgaaaataag cgctattacc
    51721 tcaattttcc tacgcttgaa tcacttgata gtcttgaact ggatcaagag atttttgtca
    51781 gagaagctag tccggtctat caagccttgt tggagcagag ttttgagacg gaattgcgca
    51841 atcaaatcaa tgcagctatt ttagttgaaa agacggactt tgcgcgcatt aaaatgactc
    51901 tgtccaatta tttttacaag gtcaaacagc agtatccttt gacagaaaaa cagcaggagc
    51961 tctatgacat tttaggagat gttaatcctg agtatgcact caagtatatg acggcttttt
    52021 tgttgaaatt tctcaaaaaa gaccagctta tgcagaaatg ccgtgatatc tttgtggaca
    52081 gtttggttgt cttaggctat attgtgcaaa atgaagatgg aaagtatgag ttggctatcg
    52141 attttgataa ggagagatta actttctact tagcgtgatt tcttgtttct gagtacattg
    52201 tttgactttc cttagtattc ggtataaact atatgtaacc ggtaacacat atcggaataa
    52261 actaaaggag acaatcatat gtcacttgaa aacaaattgg aacaagcaac aggcgctgtc
    52321 aaagaaggtt ttggtaaagt tactggagac agcaagacag aacttgaagg agctgttgaa
    52381 aaaacagttg ctaaggcaaa agacgttgta gaagacgcaa aaggtgctgt agaaggtgcc
    52441 gttgaaggtt tgaaaaacgt ttttactaaa gaataggaaa aaatcaaggg tttcattttc
    52501 ccttgatttt ttctattctt ataaataatt ttctgcgacg gctgtatctc ctgggtagga
    52561 ttctttcttg ccctggatga tttggtaaca atcggctccc ttacccgcaa taataactgc
    52621 atctaattcg tgatttgtga tagccattgc cgccttgatg gcttcttggc gatccgcaat
    52681 cttctcaaca ggatgattga tgtagctact aatttcatct gcaatggcca ttgggtcttc
    52741 atagttaggg tcatcagcag tcagaaagac ttgaatctca gggtgttgat tgaggaggag
    52801 gccaaagtcc ttacgacgac tttctccctt gtttcctgtt gatcccagaa ccagagcaat
    52861 ctttccggtt tgatgagttt caaccacatt gatgagtttt ttcagactat ccccattgtg
    52921 ggcatagtcg atgaagacct tggctccatt tttctgagtg aggacttcca tacgaccagg
    52981 aacgcgggtt gcagcgatgc cttttttgat gtcctcaaga cttgctccga gacggagaca
    53041 agcaagtcca gcagcaactg cattttcttg gttgaagttg ccaatgagtt ggatatcata
    53101 atctccagcg agtttacccg tagctgaaaa gctaaaggct ttggaattct cgatttggtt
    53161 atcaaattgg ctaccataga aatcatggtc ttgatcttta acctgttctt tcaagactga
    53221 gaagtggtcc atgtcactgt taatgatgac tgctcggcta ttttccatca agagacgctt
    53281 gtggtagaaa tagtcttcaa agctagggtg ttcaatcggg ccgatatggt ctgggctgat
    53341 attgaggaaa actcccacat caaaggttag accatagaca cgtctgacca gataggattg
    53401 actggagact tccatgatga ggtgggtacg gtcattttgc acagcctgat tcatcatgtc
    53461 aaagaggtca atactctcag gggttgtcaa cgctgactta aagaaagtct cgccatcaag
    53521 agttgtgttc atggtcgaca acatagcagg tcgatgccct tgagataaga tgttataggc
    53581 gaaataggct gctgttgtct tacccttagt accagtaaag gcaaggagtt tgagtttttc
    53641 ctgtggatta ccatagaact ccatggcaat caaactcatg gctttcttta tatcgttcac
    53701 aatgatgaca gggataccga cttcgtagtc cttttcagct acataccaag ctaagccttg
    53761 tgttatagca gaaagaaggt attctttttt aaaggcagcg ccttttgcaa aaaaaagagt
    53821 gtcttctgtt acttttcggc tgtcgtagct gatgctatca aaaacaactt tgctgtagtt
    53881 gtagtggtaa tgaccttggt caataatttc gcgaaaaagg ccatctttct ttaaaatatc
    53941 taatacagtt tcaattttta tcatactttc tattgtaaac cgaaagtcgc aaatttacaa
    54001 gtaacaagga aaagtttata atggaagata aggagttttt cctagttatc aaaattgaat
    54061 gaggaatcta tgtcgcacga aaacaatcac cagcaggccc agatgttacg ggggactgct
    54121 tggctaacgg ctagtaactt tatcagtcgc ctactcgggg ctgtttacat tatcccttgg
    54181 tacatctgga tgggggctta tgcagctaag gcaaatggtc tctttaccat gggttacaat
    54241 atctatgctt ggttcttgtt ggtttcaaca gcggggattc cagttgcggt ggccaagcaa
    54301 gttgccaagt ataataccat gcgagaagaa gagcatagct ttgccctgat tcggagcttc
    54361 ttaggcttta tgacaggact aggcctggtt tttgctttag tcttgtatgt ctttgctcct
    54421 tggctagcag acttgtctgg cgtgggcaaa gacttgatcc caatcatgca aagcttggct
    54481 tggggagtct tgattttccc gtctatgagt gttatccgag gatttttcca agggatgaat
    54541 aacctcaaac cctatgccat gagccaaatt gctgagcagg tcattcgtgt tatctggatg
    54601 ctcctagcaa cctttatcat tatgaagctc ggttcaggag attatctagc agccgttacc
    54661 caatcaacct ttgctgcctt tgtcggtatg gtagccagtt ttgcagtctt gatttatttc
    54721 cttgcccaag aaggttcact caaaagagtc tttgaaacag gagataagat taacagtaag
    54781 cgtctcttgg ttgataccat taaggaagcc attcctttta tcctgacagg gtctgccatc
    54841 cagctcttcc agattttgga tcagctgacc tttatcaata gtatgagctg gtttaccaac
    54901 tacagcaatg aggacttggt tgtcatgttt tcttatttct cagccaatcc taataaaatc
    54961 acgatgattt tgatttctgt aggggtttcg attgggagtg ttggtttgcc acttttgacg
    55021 gaaaactatg tcaaggggga cttgaaagca gcttctcgtc tggttcagga cagtctcacc
    55081 ctactcttta tgttcttgct accagcaacg gttggagtgg ttatggtagg agaacctcta
    55141 tatacagtct tctatggtaa gccagatagt ttggctctgg gcttatttgt ctttgcagtt
    55201 ttgcagtcta ttattttagg cttgtacatg gtcttgtctc caatgcttca ggccatgttc
    55261 cgcaaccgca aggccgttct ctattttatc tatggttcta ttgccaagct agtcttgcaa
    55321 ctacctacca tcgccctctt ccacagttat ggtcctttga tttcaacaac cattgctctc
    55381 atcattccta acgtcttgat gtatcgggat atttgtaaag taactggtgt caagcgcaag
    55441 gtgattttga agcgaaccat tttaatcagt ttgctgaccc tagtcatgtt tctgttaata
    55501 ggaaccatcc agtggctgtt aggatttttc ttccaaccaa gtggacgttt gtggagcttc
    55561 ttttatgtag ctcttgtcgg tgccatgggg ggtggacttt atatggttat gagtctgcgt
    55621 acctatttat tagataaggt aataggaaaa gcccaagcag atcgcctgcg agcaaaattt
    55681 aagctttcgt aaggtagcat ttataaataa aaggaataag ttgaacaatc ttttaggaga
    55741 acttgaagct tattcctttt ttagcgtaaa aatagctaaa attatatttc aaaaatagaa
    55801 aatgaggctt ttttcgattt tttggaaaaa atcattgact aaacaaacta aacgttgtat
    55861 aataaaacaa atatttaaag caggaggttc cggaaatgaa aaagtctaag agcaaatatc
    55921 taaccttggc aggtcttgtc ctgggtacag gagttttatt gagcgcgtgt ggaaattcta
    55981 gcacggcgtc aaaaacatac aactatgttt attcaagtga tccatctagc ttgaactatc
    56041 tagcagaaaa ccgcgcagca acatccgata ttgttgcaaa tttggtagac gggttattag
    56101 aaaatgacca atatgggaat attattccat cattagcaga ggattggact gtttctcagg
    56161 acggtttgac ctatacctac aaacttcgta aggatgccaa gtggtttact tctgagggag
    56221 aagaatatgc gcctgtaact gcccaggatt ttgtgacagg tttgcaatat gcagctgata
    56281 aaaaatcaga agccttgtat ctagtgcagg actctgttgc tggtttggat gactatatca
    56341 ctggtaaaac aagcgacttt tcaactgtcg gtgtcaaggc acttgatgac caaacggttc
    56401 aatatacttt ggttaaacca gaactttact ggaattcaaa aacacttgca acgatacttt
    56461 ttcctgttaa tgcagatttc ctgaaatcaa aaggggatga ttttgggaag gcggatccat
    56521 ctagtatttt gtacaatgga cctttcttga tgaaagcact tgtctcaaaa tctgctattg
    56581 aatataagaa aaaccctaat tactgggatg ctaagaatgt ctttgtagac gatgtgaaat
    56641 tgacctacta tgatggtagc gaccaagaat cactggaacg taattttaca gctggtgctt
    56701 atactacggc tcgtcttttt cctaacagct ccagctatga agggattaaa gaaaaataca
    56761 aaaacaatat catctatagt atgcaaaatt caacttcata tttctttaat tttaacctag
    56821 ataggaagtc ttacaattat acttctaaaa caagtgacat tgaaaagaaa tcgacccagg
    56881 aagcagttct caataaaaac ttccgtcagg ctatcaattt tgcttttgac agaacatctt
    56941 atggggctca gtctgaaggg aaagaaggtg caacaaagat tttgcgtaac ctagtggttc
    57001 ctccaaactt tgtcagtatc aagggaaaag actttggtga agttgtagcc tctaagatgg
    57061 tcaactatgg taaggaatgg caaggtatca actttgcgga tggtcaagac ccttactaca
    57121 atcctgagaa agccaaggct aagtttgcgg aagctaagaa agaactcgaa gcaaagggtg
    57181 ttcaattccc aatccacttg gataagactg tggaagtaac agataaagta ggcatacaag
    57241 gagttagttc tatcaaacaa tcaattgaat ctgttttagg ttctgataat gtagtgattg
    57301 acattcagca attaacatca gatgagtttg acagttcagg ctactttgct caaacagctg
    57361 ctcagaaaga ctatgattta tatcatggcg gttggggacc tgattatcaa gacccgtcaa
    57421 cctatctcga tatttttaat actaatagtg gaggagttct acaaaatctt ggactagagc
    57481 ctggagaagc caatgacaag gctaaggcag ttggactgga tgtctatact caaatgttgg
    57541 aagaagctaa taaagagcaa gatccagcca aacgttatga gaaatatgct gatattcaag
    57601 cttggttgat tgatagttct ttagttcttc caagtgtttc gcgtggggga acaccatcat
    57661 tgagaagaac cgtaccattt gctgctgcct atggtttaac cggtacaaaa ggggttgaat
    57721 catataaata cctcaaagta caagataaga ttgtcacaac agacgaatat gcaaaagcca
    57781 gagaaaaatg gttgaaagaa aaagaagaat ccaataaaaa agcccaagaa gaattggcaa
    57841 aacatgtcaa ataaaatcta attgtagata agtttgtgta agaagtcttt gtgcttaaaa
    57901 acgcataata tcaggtatat aaaatcctag atgttatgcg ttttgttata ggaagattta
    57961 ttagatttta tcctcaaatt gagttattcc cgactttatc cgttgaaata ttataaggag
    58021 tatttatgaa attaaaatta ttaagagtag atactaaggt gattatgggg agtttcttac
    58081 ttgttctgtc tagtctactt gctttgttgc ttccccttat cttaaagggt ttaatagatg
    58141 ggagttctat tgaaaatata ggttccaaag tatttcaatc gtttttgatt tttattggtc
    58201 aagccttgtt ttcttctatt ggttactatc tgtttagtca atcgggtgaa aaaagatagc
    58261 aaaaatcagg aaaaaagtga tagaggggtt gatttatgca gagaaatcct tctttgataa
    58321 gagccaaagt ggggagttga cttctgccat tgtcaatgac atgagtgtca ttcgtgagtt
    58381 tttaattacg actttcccaa atattattct gagtttagtt atggtacttg gttccattgt
    58441 agtcttattt agtcttgatt ggaatctttc tctactttta ttcatcactc ttccttgtat
    58501 gatgtttatt atcttgcccc tttccaatat cagtgaaaag tatagtcgtc gtttacagga
    58561 ggaaatcgga tttttaacag ggcaattgac tgaaaagatt caagaacatg aattaattaa
    58621 gactaaccaa gcagagaaaa gtgtacagga tgttttggat aattgtattg aaagggtaca
    58681 aaacaattca ctgaaatcag atagggttac ttcttttgag accccgtttg ctctcttatt
    58741 tatctttgcg actatagttg tgatgctaac ctatgggggt tatcgggtca gcgcaggata
    58801 tatatctgtg ggaaccttgg tttcgttttt gatttacctc tttcaattac ttaatcctat
    58861 tagtaatata gctaattttg taactattta ttctagtagc aagggatctt cagttgcact
    58921 ggagaacttg cttgcagttc ctaaagaaaa atttgaggga ggaaaatcgg tatcaggaca
    58981 agggttgaat tttaaccatg tctattttgg ttatgatgaa aatcgacctg tcttaaagga
    59041 tattacttgt tcaattttca aggggcaaaa aattgctttt gttgggccat ctggatcagg
    59101 aaaatcaacg attgtgcgtt tgttagagcg gttttataaa ccgctttcag gagatattct
    59161 aatggagcaa tcaagtatat atgattttaa cttaaaagaa tggagaagta aaatcgcttg
    59221 ggtttcacaa aataatgcag tcttatctgg cagtattcgt gacaatcttt gtctcggttt
    59281 gaatcgctta gtaactgatg atgaattgat gaaagtgcta gacttagtat cactaggtga
    59341 tgagattcgc tccatgaaag agggactaga tactgaagtt ggtgaacgcg gacgactctt
    59401 gtcagggggg cgaagccaaa gacttcaaat agctagagcc tacttaaaag atgctgaaat
    59461 tcttatattt gatgaagcca ctgctaatct tgatgcggat tctgagtatg cgattatcag
    59521 tagcctctat tctgtactaa aggagaagac ggttgtgatt atagcgcatc gcttgtcaac
    59581 ggtaaaagat gtggattgta ttttcttctt agaggagggg aaaatcactg gctcaggaac
    59641 tcataaggaa ctactggaaa atcatgagcg ttatgctcgt tttgtgcagg agcaaatgat
    59701 agagtgaagg tgtcttttga gattcaccat tttatagtct attaaaggga gcaggaaaaa
    59761 ctcccttttt atatagtttg aaactataac tagctcttga aaagaagaaa atgagttgat
    59821 gaaaataagt ggtacaatag ttactataga tttggaggaa ttgtatgagc aaggaattac
    59881 acattaacac aattttagca caagcaggga tcaagtctga tgaggcaaca ggtgctttgg
    59941 tgacaccact tcatttttca acgacctatc agcatccaga gtttggtcga tctactgggt
    60001 ttgactatac gcgcactaaa aatccaactc gtagtaaggc tgaggaagtc ttggcggcta
    60061 ttgagtcagc agactatgcc ctagcgacta gctcagggat gtcagctatt gtactggcct
    60121 ttagcgtctt tccagtagga agtaaggtct tggcagtgcg tgatctttac ggtggttctt
    60181 ttcgctggtt taaccaagtg gagcaggaag gtcatttcca ttttacctat gccaatacag
    60241 aagaagagtt gattgccgag ttagaaaagg atgtggatgt tctctatatc gaaaccccaa
    60301 ccaatccctt gatgttggaa tttgatatcg aaaaactagc aaaattggct catgctaagg
    60361 gtgccaaagt ggtggtggac aataccttct atagccctat ctaccaacgt ccgattgaag
    60421 atggagcaga tatcgttctc cattcagcaa ccaagtatct agcaggccac aatgatgtct
    60481 tggctggagt ggttgtgacc aatagtttag aactatacga gaagcttttt tacaatctta
    60541 atacaacagg ggcagtcttg tctccatttg acagctacca gttgcttcgt ggtctcaaga
    60601 ccttgtctct tcgtatggag cgctcaacag ctaacgccca agaagtggtt gcctttttga
    60661 aggattctcc agcagttaag gaagttctct acactggtcg tggaggcatg atttccttta
    60721 aagtagccga tgaaacacgc attcctcata ttttgaacag tctcaaggtc ttctcttttg
    60781 cggaaagttt gggtggagtg gaaagtctta ttacttatcc aacgactcaa actcatgctg
    60841 atattccagc agaagtacgc cattcttatg gtttgacaga tgacctcttg cgtttgtcta
    60901 ttgggattga ggatgctaga gatttgattg cagatttgcg ccaagcctta gaaggataag
    60961 acaaagatgg gaaaatatga ttttacaagc ctgcccaacc gtttagggca ccatacctat
    61021 aaatggaaag aaacagaaac ggatagtgaa gttctaccag cttggatagc ggatatggac
    61081 tttgtagtct tgcctgaaat ccaccaagcc gtgcaaactt acgcagacca actggtttat
    61141 ggttatacct atgccagtga agacttaatt aaggaagttc aaaagtggga agctacacaa
    61201 tacggttaca actttgacaa agaggctctt gtctttatcg agggtgtggt accagccatc
    61261 tcaacagcta ttcaaacctt tacaaaagaa ggcgaggcgg ttttaattaa cacgcctgtc
    61321 tacccaccct ttgctcgcag tgtcaagttg aataatcgta gattgattac taattcctta
    61381 gtggaaaagg atagtctgtt tgagattgac tttgaccaac ttgaaaagga tttggtggaa
    61441 gaggaggtta aactctatgt tctttgcaac cctcacaatc ctggtggacg tgtttgggaa
    61501 aaagaagtgt tggagaagat tggccaactc tgccaaaaac acggtgtttt gttagtttcg
    61561 gatgagattc accaagattt gaccctcttt ggtcacaaac accagtcttt caataccatc
    61621 aatcctgcct tcaaaaattt tgctatcgtc ttgagcagtg ccactaaaac atttaatatt
    61681 gctggaacaa aaaattccta tgcagtcatt gaaaatccta agttgagact ggctttccag
    61741 aaacgcctgt tggccaataa tcagcatgaa atttcaggct tgggttattt ggcgacagaa
    61801 gctgcctatc gatacggtaa agattggcta gaggaactca agcaagtctt tgaagaccac
    61861 atcaattatg tggtggatct atttggaaaa gagactaaaa tcaaggtcat gaaaccgcaa
    61921 ggtacctact tgatttggct tgacttttca gcttatgacc tgactgatga aacattgcaa
    61981 gagttgttga gaaatgaagc caaggttatc ctcaaccgtg gtttggattt tggagaggaa
    62041 ggaagtctcc atgcccgcat caatatagct atgcccaaat ctctgttgca agaagtctgt
    62101 cagcggattg tggctacttt tgccaaatgt taaaaatcca gccttctagg agaaaagtct
    62161 tcctagaagg ctattttcat aggcgaaaat atggtataat aaaaagataa ggtaaaggtg
    62221 aaaatatggc taaattgatt ccggggaaaa ttcgtatcga aggtgttgcc ctttatgaaa
    62281 ctggtaaggt tgatatcatc aaggaaaaga acaatcggct ctacgctcgc gttgcagaag
    62341 aagaactgcg ctatagttta gaggatgatt tgattttttg tgcctgtgat ttttttcaaa
    62401 agaggggcta ctgtgtgcat ttggcagcgc tagagcattt tctgaaaaat gatgagcgtg
    62461 gtcaggaaat cttgtggagt ctggaagaag gtcatgaaga aaaagaggcc gttgaaacca
    62521 aggtgacctt gggtggcaag tttttggatc gaattttatc tccaaaatca gaatgcgcct
    62581 atgagttatc agctgtgggt caggtggaag caggaaccaa tcatatcttg tggactctga
    62641 gaatcggcca aatcaatagc caaaaatact atgtcattcg ggatattcca ctttttttaa
    62701 ggattgtcga gcagagaaag tcgtatatga ttggcaagat ttatgaggag tctctttctt
    62761 gggaagcctt tgatgatgcc agccaagaac ttttgacttt cttgcacgga ctaacggagg
    62821 aagggctggt tccagacctc tttttccaaa accaaggtcg gcacctcttt ttccctctga
    62881 ccttttttga gcagggtgtg aatttactga tggccttgcc ccattttcaa tttgaccatc
    62941 aagtggatag ctaccaaacc ctgctttttc aggatatgca tgctgatgcc aatctatttg
    63001 cctttacagt aacagaatat tcggactatt ttgaaatgga aatcagtgag agtcctaggg
    63061 tcaatgtctt ttatcaagga gcagtacttt tccataaagg tcaggtttat tttttaacag
    63121 accagcagat gcgtcttctc aaggaaatta aagcgttacc tgtggatcga caaggaaaga
    63181 aatacctgca atttgatagc agtgatcgag acaaattggc ctcctgtctg actcttttta
    63241 tccagatggg caccgtttca gctccagaac gtctacaaat caaaactttt gcgccctctt
    63301 tttactttga cagggaagaa gataatcgga ttcgtttaga aattcagttt gattatggaa
    63361 atagacaggt atctagccga caagagctag aagaattacc attttcaagt gacgcggact
    63421 tagaagaaag aattttccaa gtctgtttgg ctgcgggctt tgaagccgat tttcaatctt
    63481 ggcgtcaggc cttaaaagcg gagtctgtct atcatttttt tcatgatatc attccagtct
    63541 ttgaaaaact cgggcatgtt gacctatcag ataaactaga agagctttat agcctagcga
    63601 gtcctcaggt gcagattgcc tccaagggag gtctcttgga aatccagttt gattttcaag
    63661 atattgccca ggaggaaatc gaccaagcca tacaggcctt ggttgccaat caggattttt
    63721 atattgattc gtctaatcaa gtttactttt tcgatgaaga aaccaagaaa attcgccaaa
    63781 atctacagga actggggcaa tttgaattaa aagatgggac cttgcaggct cggaaatcct
    63841 tggcctacag tttagctcat ctctttgaag ggcgagaccg tgtttctttt tcacaagaat
    63901 tccagaatct ggcccaggat ttgacgcatc cagaggactt tcctttgcaa gcaactcagg
    63961 tcaaggctga cttgcgagat tatcaggaaa agggaattgg ctggttgcag atgctccatc
    64021 attatggttt tggtgggatt ttggctgatg atatgggact tgggaaaacc cttcagacca
    64081 ttgctttttt gactagtcaa gtgacaaaag aaagtcgggt tttgattctc gctccgtcgg
    64141 gtttgattta caactgggca gatgagtttc agaaatttgc tccacagttg gatgtggctg
    64201 ttgttcatgg tttgaaagca agtcgtgagg agattcttgc cgagagccat caaatctatg
    64261 tgactagcta tgccaccttc cgtcaggaca gtgagcttta tcaggggatg gcctttgact
    64321 tccttttctt agatgaagct caggtcatga aaaatgccca gaccaagatt gcccagacct
    64381 tgagacaatt tgtggtgccg tcggtctttg ccttgtcagg aactccgatt gaaaaccatc
    64441 tgggtgagtt gtggtctatt tttcaaatcg tcatgcccgg acttttgcca agcaagaaag
    64501 aatttatgaa attgccagca gagcgagtgg ctcagtttat caagcctttc gtgatgcgac
    64561 gcaagaaaga agaagttctg actgaattgc cagacttgat tgaggtggtt tataaaaatg
    64621 aactggaaga ccagcaaaag gctatttacc ttgcccagtt acaacagatg cgagaccatc
    64681 tggctcaagt gtcagaacag gaatttcagc gaagtcgtgt ggaaatttta tctggtttga
    64741 tgcgcttgcg tcaaatatgt gacactcctg ccctgtttat ggaagattat cagggagcca
    64801 gcggcaaact agatagtctc cgagacctac tggtacaggt ggcagacggc ggacaccgtg
    64861 tcttgatttt ctctcagttc aagggaatgt tggaaaaaat tgaacaagaa ctgccagact
    64921 tgggcctgac atcctttaaa attacgggtt caaccccagc caaggaaaga caagacatga
    64981 ccaaggcctt taaccaagga gaaagagatg cctttctgat ttccctcaag gctggtgggg
    65041 tcggtctgaa cctgacaggt gcagatacag tgatcttggt tgacctttgg tggaatcctg
    65101 cggtggaagc gcaagccatt ggccgtgccc atcggatggg tcaggaagaa acggttgagg
    65161 tctatcgctt ggtgaccaag ggaaccattg aagaaaaaat tcaggaactc caagaacaaa
    65221 agaaacatct ggtgtcacaa gtattggacg gcacagagtc acgtggtagt ctgaccctag
    65281 cagaaattag agaaattttg ggaatttctg aagccagcac ttgaaaaatc aagacaatac
    65341 gctataatga agtgttgaaa ggaaatagaa aatgaaacaa gaacgatttc cattggtgtc
    65401 agatgacgag gtcatgttga ctgaaatgcc agtcatgaat ctctatgatg agtctgatct
    65461 gatcagtaat atcaagggtg agtatcgaga taaaaattat ttagaatggg ctcctattgc
    65521 tgaagaaaaa ccagtaaaac cgattgaaaa gcaagtaggg aaacctaaaa aagctccttt
    65581 aggggttaaa aaagaaggaa agagctatgc ggaggtggcg cgtgaagaag cgcgtgcaga
    65641 cttgaaaaag aaacgctctg ctaactatct aactcaggat ttcagccttg cgagacgtca
    65701 ttctcagccc agtctagtta gacagggcaa tcaaccgaca actcctttcc aaaaggaaaa
    65761 tcctggtgaa tttgtcaaat atagccaaaa attgacccag tctcattata tcttggcgga
    65821 agaagttcat tctatcccta ccaagaatga agaagtgtca gcacctgctc caaagaaaaa
    65881 caattatgat tttctaaaga agagccaaat ctacaataaa aaaagtaaac aaacagaaca
    65941 agaacgtcgg gttgcccaag agttgaatct gaccagaatg acagaatagg ggagaaaaca
    66001 tgtcaaagac atatcatttt atcggaatta agggatcagg gatgagtgcc ttggccttga
    66061 tgttgtacca gatggggcac aaggttcagg gatcagatgt tgaaaagtac tactttaccc
    66121 aacgcggtct tgagcaggca ggaattacca ttcttccttt tgatgaaaag aatctagacg
    66181 gtgatatgga aattatcgct ggaaatgcct ttcgtccaga taacaacgtc gaaattgcct
    66241 atgcggacca aaatggtatc agctacaaac gttaccatga gtttctaggt agctttatgc
    66301 gtgactttgt tagcatggga gtagcaggag cacatggaaa aacttcaacg acaggtatgt
    66361 tgtctcatgt cttgtctcac attacagata ccagcttctt gattggagat gggacaggtc
    66421 gtggttcggc caatgccaaa tattttgtct ttgaatctga cgaatatgag cgtcacttca
    66481 tgccttacca cccagaatac tctattatca ccaacattga ctttgaccat ccagattatt
    66541 tcacaagtct cgaggatgtt ttcaatgcct ttaacgacta tgccaaacaa atcaccaagg
    66601 gtctttttgt ctatggtgaa gatgctgaat tgcgtaagat tacgtctgat gcaccaattt
    66661 attattatgg ttttgaagct gaaggcaatg actttgtagc tagtgatctt cttcgttcaa
    66721 caactggttc aaccttcacc gttcatttcc gtggacaaaa cttggggcaa ttccacattc
    66781 caacctttgg tcgtcacaat atcatgaatg cgacagccgt tattggtctt ctttacacag
    66841 caggatttga tttgaacttg gtgcgtgagc acttgaaaac attttccggt gttaaacgtc
    66901 gtttcactga gaaaattgtc aatgatacag tgattatcga tgactttgcc catcatccaa
    66961 cagaaattat tgcgaccttg gatgcggctc gtcagaaata cccaagcaag gaaattgtag
    67021 cagtctttca accgcatacc tttacaagaa ccattgcctt gttggacgac tttgcccatg
    67081 ctttaaacca agcagatgct gtttatctag cgcaaattta tggctcggct cgtgaagtag
    67141 atcatggtga cgttaaggta gaagacctag ccaacaaaat caacaaaaaa caccaagtga
    67201 ttactgttga aaatgtttct ccactcctag accatgacaa tgctgtttac gtctttatgg
    67261 gagcaggaga catccaaacc tatgaatact catttgagcg tctcttgtct aacttgacaa
    67321 gcaatgttca ataggatgtt cccatggaaa ttccaattaa gatcattcag gcaagcaagt
    67381 ctgatttgcc tgagataggg gcacttcaga cctcgtcttt tccagctgaa aagcagcaac
    67441 tttcccatat tttagaagaa agtatccgta agtgtgcgga tacctttctt ctagctaggg
    67501 atgaaaatca acttttaggc tatattttat caagtcccca gtcagacaat ccgcaatatc
    67561 taaaagtaca ttctttagtc atcgagtctg accatcagag acagggcttg ggaacacttc
    67621 ttcttgcagc cttgaaagag gtggcagttg agctggatta caaagggatt cgtttggaga
    67681 gtcctgatga gctgctttcc tattttgaaa tgaacggttt tgttgatgaa gaagcaactt
    67741 tgctctatgc aactagccag ggctatagta tgatttggtt taatcccttt tatctggagg
    67801 aacaatgaaa atcagacaag caagattaga agatttggat cggattgttg aacttgaatt
    67861 tgaaaatttt tcggtcgaag aagccattcc tccttctgtc tttgaagcac atttgagaga
    67921 aattcagacc tcttttctgg ttgctgaaaa agaaggaaga atcatgggtt atatcgaagg
    67981 accagttggc ctgcaccgcc atctgcaaga ccagtctttt acagaagaaa taaaagacta
    68041 tagtcatgag cctggtggtt atatctctgt gacctgtctg tctattgcca aggaggcaca
    68101 gggactcgga ctgggtcaga aattgctgac agccttgaaa gaagttgctc ttgaagatga
    68161 gagagatggc attaatctaa cctgtcatga ctatctcatc gcctactatg aaaaacatgg
    68221 atttgtcaac gaaggccagt cccagtcaac ctttgcaggg gaaacatggt atgatatggt
    68281 ctgggaaatg aaaaaataag ttaggaaaag tatcatagat tgcttttttt ggacttttaa
    68341 gatataatat tatggattat caacaaggag gaaaaacttt tgagtgaaaa gtcaagagaa
    68401 gaagagaaat taagctttaa agagcagatt ctgagagatt tagaaaaagt aaaaggctat
    68461 gatgaagttc tgaaagaaga tgaggcagta gttcgcactc ctgcaaatga accttcaact
    68521 gaagaactca tggctgattc cttgtcaacg gtagaggaga ttatgagaaa agctcctacc
    68581 gtgcctactc acccaagtca aggtgtacca gcttctccag cagatgagat tcaaagagaa
    68641 actcctggtg ttccaagtca tccaagtcaa gatgtacctt cttctccagc ggaagaaagt
    68701 ggatcaagac caggtccagg tcctgttaga cctaagaaac ttgaaagaga atacaatgaa
    68761 accccaacaa gggtagctgt ttcctatacg acggcagaga aaaaagcaga acaagcaggt
    68821 ccagaaacac ctacgcctgc tacagaaaca gtggatatca tcagagatac atcacgtcgt
    68881 agccgtagag aaggagcaaa acccgttaag cctaagaaag agaagaagtc acatgtgaaa
    68941 gcttttgtga tttcattcct tgtattcctt gccttgctct cagcaggtgg ttactttggt
    69001 taccagtacg tgctagattc cttattacct atcgatgcta attctaagaa atatgtgacg
    69061 gttggaattc cagaaggttc aaacgttcaa gaaatcggta cgacgcttga aaaagctggt
    69121 ttggtaaagc atggtctgat ttttagtttt tatgccaagt ataaaaatta taccgacttg
    69181 aaagcaggtt actacaattt gcaaaagagt atgagtacag aagacttact caaagagttg
    69241 caaaaaggtg gaacagatga accgcaagaa cctgtacttg cgactttgac aattccagaa
    69301 ggttatacct tggatcagat tgctcaagct gtgggtcaat tgcaaggtga cttcaaagag
    69361 tctttgacag cggagacttt cttggctaaa gttcaagatg agacgtttat cagtcaagca
    69421 gtagcgaaat atcctacttt actggaaagt ttgcctgtaa aagacagcgg tgcgcgttat
    69481 cgtttggaag gatacctttt cccagctaca tactctatca aggaaagcac aactattgag
    69541 agcttgattg atgagatgtt agctgctatg gataagaacc tatctcctta ctatagtact
    69601 atcaaatcta aaaacttgac tgtcaatgag ttgttgacca ttgcttcctt ggtcgaaaaa
    69661 gaaggtgcca agacagaaga tcgtaagctc attgcaggtg tattctacaa tcgtttgaat
    69721 cgtgatatgc cacttcaaag taatattgca atcttgtatg cccaaggaaa actggggcaa
    69781 aatatcagtc tagctgagga tgttgcgatt gataccaaca ttgattcacc ttataatgtt
    69841 tataaaaatg taggtctcat gcctggtcca gtcgatagtc caagtctgga tgcgattgag
    69901 tcaagcatca atcaaactaa gagcgataac ctctactttg tagcagatgt cacagaaggc
    69961 aaggtctact atgctaacaa tcaagaagac cacgaccgca atgtcgctga acatgtcaac
    70021 agcaaattaa actaaacaaa ctaaaattat gttatacttc acataatttt ctttagaaaa
    70081 tattatcaga agaaagttga gaaaaatggc agaaaaaaca tatcctatga cccttgagga
    70141 aaaggaaaaa cttgaaaaag aattagaaga attgaaattg gttcgtcgac cagaagtggt
    70201 agaacgcatt aagattgccc gttcatacgg tgacctttca gaaaacagtg agtacgaagc
    70261 agctaaggat gaacaagcct ttgtcgaagg acaaatctct agcttagaaa caaaaatccg
    70321 ctatgctgaa atcgtcaata gcgacgcagt tgcccaggac gaagtagcga ttggtaaaac
    70381 agtcaccatc caagaaattg gtgaggacga agaagaagtt tatattatcg taggttcagc
    70441 tggtgcggat gcctttgcag gtaaggtttc aaatgaaagc ccaattgggc aggccttgat
    70501 tggcaagaaa acaggtgata cagcaaccat tgaaacgcct gttggtagct atgatgtaaa
    70561 aatcttgaag gttgaaaaaa cagcctaaaa acagaaaaag gagtggggag gcgatgtgct
    70621 tcactcactc ctttttccat tttgctattc ttcgaaaatc tcttcaaacc acgtcagcgt
    70681 cgccttgccg tatgtatggt tactgacttc gtcagtttca tctacaacct caaaaccatg
    70741 ttttgagccg acttcgtcag tttcatctac aacctcaaaa ccatgctttg agctgacttc
    70801 gtcagtttca tctacaacct caaaaccatg ctttgagctg acttcgtcag tttcatctac
    70861 aacctcaaaa ccatgctttg agctgacttc gtcagttcta tctacaacct caaaacagtg
    70921 ttttgagcaa cctgcggcta gtttcctagt ttgctctttg atttttattg agtattagat
    70981 gtatagtgca ttgaagttaa aatagtacac tttgatttct aagacattgt tagaaattag
    71041 attaaattcc ttaatcgatt tgcgcatgtt ttatttcatt tcactatact ttagattgga
    71101 aaataaggaa tcacataaat cgcaagaaat agggaatctg attcgtgttt ataaccgttc
    71161 aaaaagagaa gaggctgaaa gtgagccact taatctttat gtcgaagatg aaaagggcaa
    71221 tctcctggca ggtttgatag cagagacttt tggaaattgg ctagaaatcg agtatttgtt
    71281 tgtaaaagag gaactgcgag ggcaaggaat cggttcaaaa ctattgcaac aggcagaaag
    71341 tgaagctaag aatcgaaatt gttgttttgc ctttgtcaat acttaccagt tccaggcacc
    71401 ggacttttat cagaaacatg gctacaagga agttttttct ttgcaagact atctctacat
    71461 taggcaaaga tattattacc aaaagaatct gtaaggtgag tatggaggta taatacaaag
    71521 agaggctcgc acataagtat ggaggtggac tgatgtatat gagtaactat cgataaatac
    71581 cagttataac ctagaaattg tgtctttcta gacgatattg aggacaatat aatcgtagcc
    71641 ccaaaattag gaatcaagac ttatcaggtt aagaaaagaa gtgatgttgt tgatatttta
    71701 aacaatttat ttaaactaaa aactctctat ctattaatcc gagattcccc tctcggattt
    71761 tgtgttgctt tcattaaatt tacaggtaag acttgctagc ttcagtaaat atacacaagt
    71821 ttttcagaat agagtgaaat ccaaaagaaa atggaaataa tgaaagctct tgtaggcata
    71881 agaaaacacc tctgtgttat acttgttgtt caaccacaaa cacaagaaag gcacagagat
    71941 gcaagacaat tatactacaa aagccaaaca tttgacaatc gatagccgtc gcttaatcga
    72001 aagatggaaa aaagaaggga aatcaaatag ataaattgcc tctctgcttg gaaaagttcc
    72061 tcaaactatc cacactgaaa tcaagcgtgg gacagtccga caatgtcttg gaaaagggcg
    72121 cttcaaagag gtttattctg ccgactatgc tcaacagtct tatgaaaata atcgcaagcg
    72181 ctcggtcaag aaatcaagct tgaccaagga actaaaggaa aagattctcc actatcataa
    72241 ccaaaaattt tcgcctgaaa tgatggtgat ggctaaaggg gttaacgtgg gaatttcaac
    72301 catttactat tggattcatc atggaaaatt ggggttaagc aaacaggatc tgctttaccc
    72361 tagaaaagga aaagcgctta agaaacaggc tagcaccaac tttaaacctg ctggtcaatc
    72421 catcgaacag cggtctgaag ctatcaatct tcgcttggag aatgggcatt atgagattga
    72481 tacggttcta cttacgagag cgaaaaacta ctgcttgctt gtcttgacgg atcgaaagag
    72541 tagacatcag atcatccgat tgattccaaa taaaagtgct gaggtggtca atcaggctct
    72601 aaaactcatc ttaaaacaac acaagattct ttccatcacg gcagataatg gaacggaatt
    72661 caatcgcttg tttgatgtat tttctgagga gcacatctat tatgcgcacc cctatgcctc
    72721 ttgggaaagg ggaactaatg agaatcacaa caggctcatt cgtagatggt tacctaaggg
    72781 aaccaagaaa atgactccca aagaagtcgc attcatcgaa aagtggatta acaactatcc
    72841 taaaaaatgc ttggactaca agtcacccag agaagacttc tggatggcta acttgaactt
    72901 gaaatttagc aaaatggaaa taatttttat taaacgcttc caatagcggt taaaagttga
    72961 caaatttaaa ttttaggact acactaagta agtaaatttt attttaaagg agaatttgtt
    73021 atgaatttaa catttttagg cttatgtatt gcctgtatgg gcgtatctgt cggtgaaggt
    73081 ttattgatga atggactgtt taaatcagta gcacgccaac cagatatgct ttctgagttt
    73141 cgtagtttga tgtttttagg tgttgccttt attgaaggaa ctttctttgt aactcttgtc
    73201 ttctcattta ttatcaaata aatacatgga acgagaagaa aagggaggat tttagatgga
    73261 agaaagtatt aatccaatca tctctattgg tcctgttatc ttcaatctga ctatgttagc
    73321 catgactttg ttgattgtgg gagttatttt tgtctttatt tattgggcaa gccgcaatat
    73381 gaccttgaaa cccaaaggaa agcaaaatgt acttgagtat gtctatgact ttgttattgg
    73441 atttacagaa cctaacattg gttcgcgcta catgaaagat tactcactct ttttcctttg
    73501 tttattcctt ttcatggtga ttgccaataa ccttggctta atgacaaagc ttcaaacgat
    73561 cgatgggact aactggtgga gttcgccaac cgctaattta cagtatgact taaccttatc
    73621 ttttcttgtc attttgttga cacatataga aagcgttcgt cgtcgtggat ttaaaaaaag
    73681 tataaaatct tttatgagtc ctgtttttgt cataccgatg aatatcttgg aagaatttac
    73741 aaacttctta tctttggctt tgcggatttt tgggaatatc tttgcaggag aggtcatgac
    73801 gagtttgtta cttcttcttt cccaccaagc tatttattgg tatccagtag cctttggagc
    73861 taatttggct tggactgcat tttctgtctt tatttcctgc atccaagctt atgtttttac
    73921 tcttttgaca tctgtgtatt tagggaataa gattaatatt gaagaggaat agaaaggagt
    73981 aactgatgca cgtaacagta ggtgaattaa ttggtaattt tattttaatc actggctctt
    74041 ttattctttt gctagtcttg attaaaaaat ttgcatggtc taatattaca ggcattttcg
    74101 aagaaagagc tgaaaaaatt gcttcagata ttgacagagc tgaagaagcc cgtcaaaaag
    74161 cagaagtatt ggctcaaaaa cgcgaagatg aattggctgg tagccgtaaa gaagctaaga
    74221 caatcattga aaatgcaaag gaaacagctg agcaaagtaa ggctaatatc ttagcagatg
    74281 ctaaactaga agcaggacac ttaaaagaaa aagccaatca agaaattgct caaaataaag
    74341 tagaagcttt acagagtgtt aagggtgagg tcgcagattt gaccatcagc ttagctggta
    74401 aaatcatctc acaaaacctt gacagtcatg cccataaagc actcattgat cagtatatcg
    74461 atcagctagg agaagcttaa tggacaagaa aacagtaaag gtaattgaaa aatacagcat
    74521 gccttttgtc caattggtac ttgaaaaagg agaagaagac cgtatctttt cagacttgac
    74581 tcaaatcaag caagttgttg aaaaaacagg tctgccttct tttttaaaac aagtggcagt
    74641 agacgagtcg gataaggaaa aaacaattgc ttttttccaa gattctgtgt cgcctttatt
    74701 acaaaacttt atccaggttc tggcctacaa tcacagagca aatctttttt atgatgtgct
    74761 tgtagattgc ttgaaccgac ttgaaaaaga aacaaatcga tttgaagtga cgattacgtc
    74821 tgctcatcct ctaactgatg aacagaagac tcgtttgctc cctttgattg agaaaaaaat
    74881 gtctctgaaa gtaaggagtg taaaagaaca aatcgatgaa agtctcattg gtggttttgt
    74941 catttttgcc aatcacaaga caattgatgt gagtattaaa caacaactta aagttgttaa
    75001 agaaaatttg aaatagaaag tggtgttctt ttggcaatta acgcacaaga aatcagcgct
    75061 ttaattaagc aacaaattga aaatttcaaa cccaattttg atgtgactga aacaggtgtt
    75121 gtaacctata tcggggacgg tatcgcgcgt gctcatggcc ttgaaaatgt catgagtgga
    75181 gagttgttga attttgaaaa cggctcttat ggtatggctc aaaacttgga gtcaacagac
    75241 gttggtatta tcatcctagg tgactttaca gatatccgtg aaggcgatac aatccgccgt
    75301 acagggaaaa tcatggaagt ccctgtaggt gaaagtctga ttggtcgtgt tgtggatccg
    75361 cttggtcgtc cagttgacgg tcttggagaa atccacactg ataaaactcg tccagtagaa
    75421 gcaccagctc ctggtgttat gcaacgtaag tctgtttcag aaccattgca aactggtttg
    75481 aaagctattg acgcccttgt accgattggt cgtggtcaac gtgagttgat tatcggtgac
    75541 cgtcagacag ggaaaacaac cattgcgatt gatacaatct tgaaccaaaa agatcaagat
    75601 atgatctgta tctacgtcgc gattggacaa aaagaatcaa cagttcgtac gcaagtagaa
    75661 acacttcgtc agtacggtgc cttggactac acaatcgttg tgacagcctc tgcttcacaa
    75721 ccatctccat tgctcttcct agctccttat actggggttg ctatggcgga agaatttatg
    75781 tatcaaggta agcatgtttt gattgtatac gatgatctat caaaacaagc ggtagcttat
    75841 cgtgaactat cgctcttgct tcgtcgtcct ccaggtcgtg aagccttccc aggggatgtt
    75901 ttctatctcc acagccgttt gcttgagcgc tcagctaaag tttctgatga acttggtggt
    75961 ggatcaatta cagccctacc atttatcgag acacaagcag gagatatctc agcctatatc
    76021 gcaaccaacg tgatttctat cactgatgga caaatcttcc ttggcgatgg cctcttcaat
    76081 gcaggtattc gtccagccat cgatgcgggt tcatctgtat ctcgtgtagg tggttctgca
    76141 caaatcaaag ccatgaagaa ggttgctggt acacttcgta tcgaccttgc ttcataccgt
    76201 gagttggaag cctttactaa gtttggttct gacttggacg cagcaacaca ggctaagttg
    76261 aaccgtggac gtcgtaccgt tgaggtcttg aaacaacctg ttcacaaacc attacctgtt
    76321 gagaaacaag taaccattct ttatgctttg acacatggtt tcttggatac tgttccagta
    76381 gatgatattg ttcgtttcga ggaagagttc catgccttct ttgatgctca acatccagag
    76441 attttggaaa ccattcgtga tacaaaagac ttgccagaag aagcagtctt ggatgctgcg
    76501 attacagagt ttctcaatca atctagcttc caataagaat agaggtgtca gatggcagtg
    76561 tctctaaatg atattaaaac aaaaatcgcc tcaacaaaaa atacgagtca aatcactaat
    76621 gccatgcaaa tggtatcggc tgctaagtta ggtcgctctg aagaagctgc tcgcaacttc
    76681 caagtttacg ctcagaaagt gcgtaaactt ttgacagata tccttcatgg taatggagct
    76741 ggtgcttcaa ctaatccgat gttgattagc cgttctgtga agaagacagg ctatatcgtt
    76801 atcacttcag accgcggttt ggttggaggt tataattcct ctattttgaa agctgttatg
    76861 gagttgaaag aagaatacca cccagacggt aaaggttttg aaatgatctg tatcggtggg
    76921 atgggagctg atttctttaa ggctcgcggt attcaaccac tttatgaatt acgtggcttg
    76981 gcagaccaac ctagctttga tcaagttcgt aagattattt caaaaactgt tgaaatgtac
    77041 caaaatgaac tctttgatga gctttatgtt tgctacaacc accatgtcaa tacgctaacc
    77101 agtcaaatgc gtgtggaaca aatgcttccg attgttgact tggatccaaa tgaagcggat
    77161 gaagagtaca gcttgacttt tgaattggaa accagccgag aagaaattct ggagcagttg
    77221 ttgcctcagt ttgcagaaag tatgatttac ggtgccatta tcgatgccaa gacagctgag
    77281 aatgctgcgg gtatgacagc catgcaaaca gcgacagata atgctaagaa agtcatcaat
    77341 gatttgacaa ttcagtataa ccgtgccaga caggcggcga ttacacaaga aattacagaa
    77401 atcgtagcag gtgctagtgc cttagaatag gctctagtcc agctcgtatg aaaatgaact
    77461 taggacctag ttgagctagg aaccgacagt atcttatata gaataggaga aggagatgag
    77521 ttcaggtaaa attgctcagg ttatcggtcc cgttgtagac gttttgtttg cagcagggga
    77581 aaaacttcct gagattaaca atgcacttgt cgtctacaaa aatgacgaaa gaaaaacaaa
    77641 aatcgtcctt gaagtagcct tggagttagg agatggtatg gttcgtacta tcgccatgga
    77701 atcaacagat gggttgactc gtggaatgga agtattggac acaggtcgtc caatctctgt
    77761 accagtaggt aaagaaactt tgggacgtgt cttcaacgtt ttgggagata ccattgattt
    77821 ggaagctcct tttacagaag acgcagagcg tcagccaatt cataaaaaag ctccaacttt
    77881 tgatgagttg tctacctctt ctgaaatcct tgaaacaggg atcaaggtta ttgaccttct
    77941 tgccccttac cttaaaggtg gtaaagttgg acttttcggt ggtgccggag ttggtaaaac
    78001 cgtcttaatc caagaattga ttcacaacat tgcccaagag cacggtggta tttcagtatt
    78061 tactggtgtt ggggaacgta ctcgtgaggg gaatgacctt tactgggaaa tgaaagaatc
    78121 aggcgttatc gagaaaacag ccatggtctt tggtcagatg aatgagccac caggagcacg
    78181 tatgcgtgtt gcccttactg gtttgacaat cgctgaatac ttccgtgatg tggaaggcca
    78241 agacgtgctt ctctttatcg ataatatctt ccgtttcact caggctggtt cagaagtatc
    78301 tgcccttttg ggtcgtatgc catcagccgt tggttaccaa ccaacacttg ctacggaaat
    78361 gggtcaattg caagaacgta tcacatcaac caagaagggt tctgtaacct ctatccaggc
    78421 tatctatgtg ccagcggatg actatactga cccagcgcca gcaacagcct tcgctcactt
    78481 ggattcaaca acaaacttgg aacgtaaatt ggtacaattg ggtatctacc cagccgttga
    78541 cccacttgct tcaagctcac gtgccttggc acctgaaatc gttggagaag agcactatgc
    78601 agttgctgct gaagtaaaac gtgtccttca acgttaccat gaattgcaag atatcattgc
    78661 tatccttggt atggatgagc tttctgatga agaaaagacc ttggttgctc gcgcccgtcg
    78721 tatccagttc ttcttgtcac aaaacttcaa cgttgcggaa caatttactg gtcagccagg
    78781 ttcttatgtt ccagttgctg aaactgtacg tggctttaag gaaatccttg atggtaaata
    78841 cgaccacttg ccagaagatg ccttccgtgg tgtaggttct atcgaagatg tgattgcaaa
    78901 agctgaaaaa atgggatttt aagaggtgac ctatggctca gttaactgtc cagatcgtga
    78961 caccagatgg tctcgtctat gatcaccatg ccagctatgt atcggttcga actctggatg
    79021 gtgagatggg gatcttgcca cgacatgaaa atatgattgc ggttttagca gttgatgaag
    79081 taaaggtaaa acgtatcgat gataaagatc acgtgaactg gattgcagta aacggtggcg
    79141 ttattgaaat tgccaatgat atgatcacaa tcgtcgctga ctctgcagaa cgtgctcgtg
    79201 atatcgatat tagccgtgca gaacgtgcca aacttcgtgc agaacgtgca attgaagaag
    79261 cacaagacaa acatttgatt gaccaagaac gtcgtgctaa gattgctttg caacgtgcca
    79321 ttaaccgtat taatgtcgga aatagactat aagaaaaaat gaacttgaaa ataccaagtt
    79381 cattttttag gctctttgtc aactgtagtg ggttgaaaaa
//
LOCUS       DAVLBE010000003        67465 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.003, whole genome shotgun sequence.
ACCESSION   DAVLBE010000003 DAVLBE010000000
VERSION     DAVLBE010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 67465)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 67465)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..67465
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.003"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(37..972)
                     /locus_tag="VXB91_000168"
     CDS             complement(37..972)
                     /locus_tag="VXB91_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HEV0469686.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTSIWKAIKRLEQE
                     GIEIDSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAASLFKATAPITRNELIIEIWRAFFETPAEELLYLYKKQSFILGKEVTFTLQQKDYK
                     GLAKDISENGKLLVQCDNGKEIWLNSGEISLNSWK"
     gene            complement(969..1829)
                     /locus_tag="VXB91_000169"
     CDS             complement(969..1829)
                     /locus_tag="VXB91_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEV0469687.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIT
                     KGQGKFHYKGKIVDLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKAPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRAGQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQTPSHTRKEYS
                     QYQLVRKATL"
     gene            1937..4099
                     /locus_tag="VXB91_000170"
     CDS             1937..4099
                     /locus_tag="VXB91_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HEV0469688.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHNVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATIASYSKLD
                     NNSNQEVVIHKDFSFMADFPAADYEIATLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHIMLSEFSKKERPILINNWEATY
                     FDFQREKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRQHPDWAIQVPDYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQLLSYHEIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMIRYFPQVWASDNTDAIARLPIQYGSSYLYPTISMGA
                     HVSAVPNHQMGRMTPLETRGHVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTASNEAAVQFNYGNQTIVTYVRVLSVVETMETTLKLKDLDEEGLY
                     KLQENGEVYSGAELMYAGLTVILSQGDFLSRQYIFRKL"
     gene            4191..5450
                     /locus_tag="VXB91_000171"
     CDS             4191..5450
                     /locus_tag="VXB91_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV0469689.1"
                     /translation="MEWYKKIGLLATTGLALFGLGACSNYGKSADGTVTIEYFNQKKE
                     MTKTLEEITRDFEKENPKIKVKVVNVPNAGEVLKTRVLAGDVPDVVNIYPQSIELQEW
                     AKAGVFEDLSNKDYLKRVKNAYAEKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV
                     PETWDEFEQLVKDIVAKGQTPFGIAGADAWTLNGYNQLAFATATGGGKEANQYLRYSQ
                     PNAIKLSDPIMKDDIKVMDILRINGSKQKNWEGAGYTDVIGAFARGDVLMTPNGSWAI
                     TAINEQKPNFKIGTFMIPGKEKGQSLTVGAGDLAWSISATTKHPKEANAFVEYMTRPE
                     VMQKYYDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTDRHLVWLQQYWTSEADFHTLTM
                     NYVLTGDKQGMVNDLNAFFNPMKADVD"
     gene            5464..6330
                     /locus_tag="VXB91_000172"
     CDS             5464..6330
                     /locus_tag="VXB91_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0469690.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIITIAMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFLQTSLLGTKWGAIFAAVFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSMVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFLLIVVIS
                     IIQLRVSKKFEI"
     gene            6344..7177
                     /locus_tag="VXB91_000173"
     CDS             6344..7177
                     /locus_tag="VXB91_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV0469691.1"
                     /translation="MKQDERKALIGKYILLILGSVLILVPLLATLFSSFKPTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     VFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIISGMSNGAV
                     K"
     gene            7178..7258
                     /locus_tag="VXB91_000174"
                     /pseudo
     CDS             7178..7258
                     /locus_tag="VXB91_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            7535..8977
                     /gene="gtfA"
                     /locus_tag="VXB91_000175"
     CDS             7535..8977
                     /gene="gtfA"
                     /locus_tag="VXB91_000175"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HEV0469692.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYDNLEEHFGDAIGGVHLLPFF
                     PSTGDRGFAPVDYDEVDSAFGDWEDVKRLGEKYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKDLFLNWDKFWPENRPTQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGCDLIRLDAFAYAVKKLDTNDFFVEPDIWDLLD
                     KVRDIAAEYGTELLPEIHEHYSIQFKIADHDYYVYDFALPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTTLDTHDGIGVVDVKDILTDEEIDYASNELYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQVYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAKEVQRPVVKALLNLFSFRNRSEAFDLEGTTEIETPTAHSIVIKRQ
                     NKDKSVTAVAEIDLQNQTYRVIENGVEVTF"
     gene            9115..10308
                     /locus_tag="VXB91_000176"
     CDS             9115..10308
                     /locus_tag="VXB91_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HEV0469693.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVFCLYIIS
                     LIFTGDMKSILQKMGEHSMLLLFLGYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMHSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            10994..12973
                     /locus_tag="VXB91_000177"
     CDS             10994..12973
                     /locus_tag="VXB91_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0469694.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKTSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKANAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVQVGLKEYDKLVDEAAKETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KAVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            13040..14536
                     /locus_tag="VXB91_000178"
     CDS             13040..14536
                     /locus_tag="VXB91_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0469695.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGALTFLLALPTIALVY
                     IVRLIGSSISLPDSFPILGAGDWRSYVLPAVILGLLGAPGTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPGAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            14536..15462
                     /locus_tag="VXB91_000179"
     CDS             14536..15462
                     /locus_tag="VXB91_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0469696.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSVRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            15471..16538
                     /locus_tag="VXB91_000180"
     CDS             15471..16538
                     /locus_tag="VXB91_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0469697.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKDWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSKTHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            16549..17475
                     /locus_tag="VXB91_000181"
     CDS             16549..17475
                     /locus_tag="VXB91_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0469698.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQNIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQAELARYQKGLN"
     gene            18042..18902
                     /locus_tag="VXB91_000182"
     CDS             18042..18902
                     /locus_tag="VXB91_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV0469699.1"
                     /translation="MSQFITHQSLYATREGFVDELAKQGYVEGENIEIDLQNAQGEQR
                     NLKTISQQLAESSDVVLAIARPSAQSLANTTQTTPVIFSAVTDPVSAKLVESREHPGG
                     NVTGTSDQSSDAISTQINLIKKVLPKAKTIGILYTQSEPNSVVQKDEAKRLLKEKGFT
                     VVEKTILDSNNVKAAAESLMAEVDMVFVPTDNIISLTMETVKQVSIKHKVPVFGGSTE
                     MIAVGGLYNYGTNYEELVRQTARMLIRVLKGEKPENIAVELPEKLELHTNQEMADALG
                     IDISKLEGKE"
     gene            18914..19807
                     /locus_tag="VXB91_000183"
     CDS             18914..19807
                     /locus_tag="VXB91_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001012086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0469700.1"
                     /translation="MNFVLSSLSEGLLWSIVAIGVYLTFRILDIADMTAEGAFPLGAA
                     VVVSQIQAGANPWLATLLALLAGMVAGLVSGMLHTKMKIPALLTGIVTLTGLYSINIK
                     IMGSVPNLSLGDSATVFKQLASLGLTNEGTVFSLSLACFLLVCLVLTLLMKTEIGLVL
                     RSTGDNIPMSEANGVNVDTMKIVGYMISNGLIALCGSLFAQNDGFSDVTSGTGTIVVG
                     LSSVIIAEVLIHDLTIGGRLLSIGIGAIVYRLIILNIYEIPNLDQNLVRLFNAILLAL
                     VLFAPELQKRLKIRGLKLRNE"
     gene            19820..20623
                     /locus_tag="VXB91_000184"
     CDS             19820..20623
                     /locus_tag="VXB91_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000157668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0469701.1"
                     /translation="MTSLLTLENIHKTFEAGTVNENHVLKGLDLEVEEGDFISVIGGN
                     GAGKSTLMNILAGNLSVDEGDLLLAGKSIKNLSVRKRAKDIARVFQDPKMGTASRLTI
                     EENMAIALRRGQKRGLGWGVKEKDRIQFQEALKELNIGLENRLKVDTQYLSGGQRQAL
                     TLVMTDLMKPKLLLLDEHTAALDPKTSQMVMDLTQKIVEHHQWTTLMITHDMNHAIEY
                     GNRLIMLYQGKIVVDVKGEEKKHLTVEDLMHLFQKNSGQSLVSDELVLG"
     gene            complement(20656..21366)
                     /gene="treR"
                     /locus_tag="VXB91_000185"
     CDS             complement(20656..21366)
                     /gene="treR"
                     /locus_tag="VXB91_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HEV0469702.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIREQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
     gene            21551..23518
                     /gene="treP"
                     /locus_tag="VXB91_000186"
     CDS             21551..23518
                     /gene="treP"
                     /locus_tag="VXB91_000186"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HEV0469703.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGDDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVV
                     QRVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTVNRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKGLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFAYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKTEGDTNLQAEFVAQEEAEFVNHEPVELTSVEII
                     SPLTGQVKELSQATDPIFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVTVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTATIPGTYPTTIQAGASLMVATRI"
     gene            23696..25321
                     /gene="treC"
                     /locus_tag="VXB91_000187"
     CDS             23696..25321
                     /gene="treC"
                     /locus_tag="VXB91_000187"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HEV0469704.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTENGIGDFRGIIEKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCVGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWAPFGDTGKYYLHLFDETQA
                     DLNWRNSNVRKELFKVVNFWRDKGVKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQMLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDTSENAGFSTGTPWLKVGKSYKDINVENEIKGLIFTFY
                     QDLIRLRKEMPIISEGNYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            25577..25825
                     /locus_tag="VXB91_000188"
     CDS             25577..25825
                     /locus_tag="VXB91_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HEV0469705.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            26032..26826
                     /gene="racE"
                     /locus_tag="VXB91_000189"
     CDS             26032..26826
                     /gene="racE"
                     /locus_tag="VXB91_000189"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HEV0469706.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIHVEHVEL"
     gene            26823..27794
                     /locus_tag="VXB91_000190"
     CDS             26823..27794
                     /locus_tag="VXB91_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HEV0469707.1"
                     /translation="MTNKIYEYKDDQDWYVGSYSIFGGVNSLSDYKTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGESSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            27770..28291
                     /locus_tag="VXB91_000191"
     CDS             27770..28291
                     /locus_tag="VXB91_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEV0469708.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWLEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            28288..28749
                     /locus_tag="VXB91_000192"
     CDS             28288..28749
                     /locus_tag="VXB91_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEV0469709.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDAEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            28740..29480
                     /gene="xerD"
                     /locus_tag="VXB91_000193"
     CDS             28740..29480
                     /gene="xerD"
                     /locus_tag="VXB91_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HEV0469710.1"
                     /translation="MPMRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETS
                     LKIYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEIL
                     YLDSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQQRIVT
                     IPTALLSELEPLMGQTYLFERGEKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFIL
                     RQIENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            29480..30208
                     /locus_tag="VXB91_000194"
     CDS             29480..30208
                     /locus_tag="VXB91_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HEV0469711.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            30227..30796
                     /locus_tag="VXB91_000195"
     CDS             30227..30796
                     /locus_tag="VXB91_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HEV0469712.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKPQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            30783..31505
                     /locus_tag="VXB91_000196"
     CDS             30783..31505
                     /locus_tag="VXB91_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEV0469713.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVANKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLTIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            31505..31747
                     /gene="yidD"
                     /locus_tag="VXB91_000197"
     CDS             31505..31747
                     /gene="yidD"
                     /locus_tag="VXB91_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HEV0469714.1"
                     /translation="MKRILIAPVRFYQRFISPVFPPSCRFELTCSNYMIQAIEKHGFK
                     GVLMGLARILRCHPWSKTGKDPVPDHFSLKRNQEGE"
     gene            complement(31972..32937)
                     /locus_tag="VXB91_000198"
     CDS             complement(31972..32937)
                     /locus_tag="VXB91_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0469715.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEVTI
                     KSSLAEVKLSKVPEKIVTFDLGAADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETGTQKAKEELAKLDKSIQEVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTKFEDSRHGQEVSFESVKEINPDILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(33033..33785)
                     /locus_tag="VXB91_000199"
     CDS             complement(33033..33785)
                     /locus_tag="VXB91_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0469716.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINIASQYADEIVAFKDGQVFSKGR
                     TDQIMQADLLSQLYEIPITLADINDKKICIYS"
     gene            complement(33782..34738)
                     /locus_tag="VXB91_000200"
     CDS             complement(33782..34738)
                     /locus_tag="VXB91_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HEV0469717.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSLFFLALQGYLKTLMKQDLVFILLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFGFMLANLTYLIVKDYQHKLLFIVAILVGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRARQ"
     gene            complement(34728..35687)
                     /locus_tag="VXB91_000201"
     CDS             complement(34728..35687)
                     /locus_tag="VXB91_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0469718.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAPKLGMVLSLFVFPSAS
                     LTQKMLFAFVSSIVFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKETSESLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKRYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLVFILLLWRGGRKDAD"
     gene            complement(36110..36811)
                     /gene="galE"
                     /locus_tag="VXB91_000202"
     CDS             complement(36110..36811)
                     /gene="galE"
                     /locus_tag="VXB91_000202"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEV0469719.1"
                     /translation="MTKTILVTGGTSYIGSHTVKALLNAGYKVHVLDNLSTGNRAAVD
                     SRASFKELDVYDASALKAYLEENQIDAVLHCAGEIVVSESIENPSKYFTANVAGMNQV
                     LKVLSEVGIQKIMFSSTASLYGNNCIDKPVTEDTLLDPVNPYAETKLMGERMIYWMAN
                     RYDWKYVIFRYFNVAGAEMDASNGLRVKNPTHIIPNINKTALGQNDSLKIFGDDYDTR
                     DGSCIRDYIYVLDLA"
     gene            37212..38276
                     /gene="pepA"
                     /locus_tag="VXB91_000203"
     CDS             37212..38276
                     /gene="pepA"
                     /locus_tag="VXB91_000203"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HEV0469720.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPHVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKAEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALSGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
     gene            38298..38594
                     /locus_tag="VXB91_000204"
     CDS             38298..38594
                     /locus_tag="VXB91_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEV0469721.1"
                     /translation="MVEPNLESLIKDLYNHARHDLSEDLVAALLETTKKLPTTNEQLQ
                     AVRLSSLVNRELLLNPKHPAPELLNLARFVKREEAKYRGTATSALMYEELFKML"
     gene            39276..39719
                     /locus_tag="VXB91_000205"
     CDS             39276..39719
                     /locus_tag="VXB91_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV0469722.1"
                     /translation="MKDSHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKFQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKENEV"
     gene            39723..40487
                     /locus_tag="VXB91_000206"
     CDS             39723..40487
                     /locus_tag="VXB91_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HEV0469723.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGDTYIQHSTGVPDGK
                     EGFAAFFADFFERHPERQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFRADENG
                     RIVEHWDVIDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTETFQNGELEQW
                     SDYVADDLIQHNHEIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLENGKIVEHWDNKEVIPKVEDLTNRGKF"
     gene            40502..41230
                     /locus_tag="VXB91_000207"
     CDS             40502..41230
                     /locus_tag="VXB91_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0469724.1"
                     /translation="MIEYKNVALRYTEKDVLRDVNLQIENGEFMVLVGPSGSGKTTMI
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLTTGYVLQAIALFPNLTVEENIALIPEM
                     KGWTKEEIAQKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKIFLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVA
                     NPETILKVPATDFVADLFGGSVHD"
     gene            41223..42743
                     /locus_tag="VXB91_000208"
     CDS             41223..42743
                     /locus_tag="VXB91_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HEV0469725.1"
                     /translation="MTNLIATFQDRFSDWLTALSQHLQLSLLTLLLAILLAIPLAVYL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLKGIDPSLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLATLIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVAL
                     LLGLSYSPALLAQKEKENLIIAGKIGPEPEILANMYKLLIEENTSMTATVKPNFGTTS
                     FLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVATMQPALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELERVLNTLAGKITESQMSQLNYQVGVEGKSAKQVAKEFLQEQGLLKK"
     gene            43088..43894
                     /locus_tag="VXB91_000209"
     CDS             43088..43894
                     /locus_tag="VXB91_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HEV0469726.1"
                     /translation="MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKAIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLLN"
     gene            complement(44061..44597)
                     /locus_tag="VXB91_000210"
     CDS             complement(44061..44597)
                     /locus_tag="VXB91_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEV0469727.1"
                     /translation="MTNIDRRISKTKKAIYQAFIQLLNAKGYEATTVQDIIDLADVGR
                     STFYCHYESKELLLDQLCRYLFHHLFEREQAISTEDYLAHLFLHFHKNQDHITSLLFS
                     KNDYFLRQLHKELEHHVYSVLADNLKEAHPNMPTSYLQHFVVTNFIETLTWWLKKGQD
                     FTDQEVVQFYLDLLIPKN"
     gene            44730..45620
                     /locus_tag="VXB91_000211"
     CDS             44730..45620
                     /locus_tag="VXB91_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HEV0469728.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGVFGSSAVLADSVHDLGDA
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGALVTAVILVTGSVLVILENVTKILHP
                     QPVNDEGILWLGIIAITINLLASLVVGKGKTKNESILSLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALPRFWSTLKIFLDAVPEGLDIKQVKSGLERLDNV
                     ASLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            45864..46217
                     /locus_tag="VXB91_000212"
     CDS             45864..46217
                     /locus_tag="VXB91_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEV0469729.1"
                     /translation="MNIKSASDLLGISADTIRYYERVGLVPPITRTATGIRDFQDQDI
                     EALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQLQTAL
                     NRLNLKIKLYKEGKF"
     gene            46218..47255
                     /locus_tag="VXB91_000213"
     CDS             46218..47255
                     /locus_tag="VXB91_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEV0469730.1"
                     /translation="MKSAVYTKAGQVGLASIERPQIIEADDVIIRVVRACVCGSDLWR
                     YRNPETKAGHKNSGHEAIGIVEEAGEAITTVKPGDFVIVPFTHGCGECDACLAGFDGS
                     CDNHIGNNLGGDFQAEYIRFHYANWALVKIPGQPSDYTEGMLKSLLTLADVMPTGYHA
                     ARVANVQKGDKVVVIGDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVV
                     AERGQEGITKVREILGGGADAALECVGTEAAIEQALGVLHNGGRMGFVGVPHYNNRAL
                     GSTFMQNISVAGGAASATTYDKQFLLKAVLDGDINPGRVFTSSYKLEDIDQAYKDMDE
                     RKTIKSMIIIE"
     gene            complement(47302..48309)
                     /gene="galR"
                     /locus_tag="VXB91_000214"
     CDS             complement(47302..48309)
                     /gene="galR"
                     /locus_tag="VXB91_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HEV0469731.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIEDKRLENFRNYSQAKGIYHDELIFQGN
                     FTAQSGYDLMKEAIQSLGDQLPPAFFAASDSLAIGALRALQEAGINLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHGRKIPSLTMLGTRLTLRESTLNQ
                     E"
     gene            48474..49652
                     /locus_tag="VXB91_000215"
     CDS             48474..49652
                     /locus_tag="VXB91_000215"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HEV0469732.1"
                     /translation="MAQHLTTEVLRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAARKRDDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLDRLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELDEWAVDQYSYLIKDENRLKRAR
                     HAVLENQRTLKAQAALQAGDLETFGRLMNASHVSLEHDYEVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEAFKEAVGKHYEEVVGYAPSFYIAEVAGGTRVLD
                     "
     gene            49671..51152
                     /locus_tag="VXB91_000216"
     CDS             49671..51152
                     /locus_tag="VXB91_000216"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEV0469733.1"
                     /translation="MILVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKDQLVEEAVRLEMIEDSQTAREILGTELMDLVTPYPSQVNRDFWEAYVHSPE
                     QAIEDFYQLSQKNDYIKLKAIAKNIAYRVPSDYGELEITINLSKPEKDPKEIAVAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARSNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVEQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKTFRFAGFEQVKAGIIKWPMSVLRLTSDSKEDLINLADKIFQEWRQYSDSSVQ
                     ILAETDGTPHHTITPIARKRDGQFELDLVLRDNQTSAEHPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFVRVLEDAGVYKQTEQGQTAFMRFVEQVGILLD"
     gene            51222..51626
                     /locus_tag="VXB91_000217"
     CDS             51222..51626
                     /locus_tag="VXB91_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HEV0469734.1"
                     /translation="MKDFHFDAISAFESYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVTGQRSEERRVSI"
     gene            51807..52571
                     /locus_tag="VXB91_000218"
     CDS             51807..52571
                     /locus_tag="VXB91_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-2 restriction enzyme DpnI"
                     /protein_id="HEV0469735.1"
                     /translation="MELHFNLELVETYKSNSQKARILTEDWVYRQSYCPNCGNNPLNH
                     FENNRPVADFYCNHCSEEFELKSKKGNFSSTINDGAYATMMKRVQADNNPNFFFLTYT
                     KNFEVNNFLVLPKQFVTPKSIIQRKPLAPTARRAGWIGCNIDLSQVPSKGRIFLVQDG
                     QVRDPEKVTKEFKQGLFLRKSSLSSRGWTIEILNCIDKIEGSEFTLEDMYRFESDLKN
                     IFVKNNHIKEKIRQQLQILRDKEIIEFKGRGKYRKL"
     gene            52568..53029
                     /locus_tag="VXB91_000219"
     CDS             52568..53029
                     /locus_tag="VXB91_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein DpnD"
                     /protein_id="HEV0469736.1"
                     /translation="MKTKQLVASEEVYDFLKVIWPDYETESRYDNLSLIVCTLSDPDC
                     VRWLSENMKFGDEKQLALMKEKYGWEVGDKLPEWLHSSYHRLLLIGELLESNLKLKKY
                     TVEITETLSRLVSIEAENPDEAERLVREKYKSCEIVLDADDFQDYDTSIYE"
     gene            complement(53080..54342)
                     /locus_tag="VXB91_000220"
     CDS             complement(53080..54342)
                     /locus_tag="VXB91_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HEV0469737.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGNGAMFGAL
                     IASGIYVVLVSGIFSKVANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LAAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPTP
                     LYFGMPTFEISSIVMMCIIATVSMVESTGVYLALSDITKDPIDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIVVASLLAIVLNAVLNHKKK"
     gene            complement(54342..54923)
                     /locus_tag="VXB91_000221"
     CDS             complement(54342..54923)
                     /locus_tag="VXB91_000221"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HEV0469738.1"
                     /translation="MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMREIGKVFAE
                     KFAATGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL"
     regulatory      complement(55323..55418)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            complement(55801..56040)
                     /locus_tag="VXB91_000222"
     CDS             complement(55801..56040)
                     /locus_tag="VXB91_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEV0469739.1"
                     /translation="MLEEGTKDQLAELTYPFGRGVNLSFGIKDVPKLYQKVMEANYPI
                     YRLLTKRKFRVSDPYIYPHKFAVLDPDGYFLRFSE"
     gene            complement(56085..56183)
                     /locus_tag="VXB91_000223"
     CDS             complement(56085..56183)
                     /locus_tag="VXB91_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEV0469740.1"
                     /translation="MDYNAVIPEFLVSNIEQSRSFYCGLLGFRIEY"
     gene            complement(56195..57022)
                     /gene="xth"
                     /locus_tag="VXB91_000224"
     CDS             complement(56195..57022)
                     /gene="xth"
                     /locus_tag="VXB91_000224"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HEV0469741.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAENADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTISFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDVKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            57156..57612
                     /locus_tag="VXB91_000225"
                     /pseudo
     CDS             57156..57612
                     /locus_tag="VXB91_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            57609..58139
                     /locus_tag="VXB91_000226"
     CDS             57609..58139
                     /locus_tag="VXB91_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000174443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HEV0469742.1"
                     /translation="MTLNYIEILIKLVLTLKWLNNNVHFVKRLIDGKPTLLIKNGNID
                     PEACRSVGLSASDVALKLRSQGIFQMKQVKRAVQEQNGQLIVVQMGDENPKYPVVTDG
                     VIQVDVLESIGRSEEWLLDNLSKQGHDNVANIFIAEYDKGAVTVVTYEKEKPGVLYSS
                     KISSNRVNVALPYVGY"
     gene            58267..60012
                     /locus_tag="VXB91_000227"
     CDS             58267..60012
                     /locus_tag="VXB91_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0469743.1"
                     /translation="MSIIQKLWWFFKLEKRRYLVGIVALVLVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSSAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYATSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLLFVGSSYVLTLLVGSLVVQEGQITVGN
                     LVTFISYLDMLVWPLMAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     RLEYAIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGAI
                     YLNGHDIRDYRLTDLRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSAVEEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRTMILDPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADLILVLQNGQIIERGRHEDLLALDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            60002..61753
                     /locus_tag="VXB91_000228"
     CDS             60002..61753
                     /locus_tag="VXB91_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0469744.1"
                     /translation="MQNKQEQWTVLKRLMSYLKPYGLLTFLALSFLLATTVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLAYANRSVALDALFLRPAMSLLKLLGYAVLMTYFGYRGLSIG
                     ITAGTMYAFIQYINRLFDPLIEVTQNFSTLQTSMVSAGRVFALIDERTYEPLQENGQA
                     KVKEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQEISDEQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLTLGG
                     TYHKMYSLQAGAMAYTL"
     gene            61926..62618
                     /locus_tag="VXB91_000229"
     CDS             61926..62618
                     /locus_tag="VXB91_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEV0469745.1"
                     /translation="MLKWEDLPVEMKSSEVESYYQLVSKRKGSLIFKRCLDWVLALVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVTDADKKGSLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSPEMMATLLL
                     QAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMRYNLAYLREFSFFGDI
                     KIMFQTVFEVLK"
     gene            62661..63887
                     /locus_tag="VXB91_000230"
     CDS             62661..63887
                     /locus_tag="VXB91_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase family
                     protein"
                     /protein_id="HEV0469746.1"
                     /translation="MPNYNIPFSPPDITEAEIAEVADTLRSGWITTGPKTKELERRLS
                     LYTQTPKTVCLNSATAALELILRVLEVGPGDEVIVPAMTYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSTYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWKANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAGSRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFENEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            65018..67177
                     /gene="pfbA"
                     /locus_tag="VXB91_000231"
     CDS             65018..67177
                     /gene="pfbA"
                     /locus_tag="VXB91_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HEV0469747.1"
                     /translation="MLKIVKKLEVLMKYFVPNEVFSIRKLKVGTCSVLLAISILGSQG
                     ILSDEVVTSSSPMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNS
                     ISSNGTIRSNSQLDNRTVESTVTSTNENKSYKEDVISDRIIKKEFEDTALSVKDYGAV
                     GDGIHDDRQAIQDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKSHTHLELNEKATILN
                     GINIKNHPSIVFMTGLFTDDGAQVEWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLI
                     NSSGAFAIGNSNNVTIKNVTFKDSYQGHAIQIAGSKNVLVDNSRFLGQALPKTMKDGQ
                     IISKESIQIEPLTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTL
                     STQNPSNIKILNNHFDNMMYAGVRFTGFTDVLIKGNRFDKKVKGESVHYRESGAALVN
                     AYSYKNTKDLLDLNKQVVIAENIFNIADPKTKAIRVAKDSAEYLGKVSDITVTKNVIN
                     NNSKETEQPNIELLRVSDNLVVSENSIFGGKEGIVIEDSKGKITVLNNQFYNLSGKYI
                     SFIKSNANGKEPVIRDSDGNFNIVTENGLYKIVTNNLSDKNEKEKNKEEKQSNSNNVI
                     DSNQKNGEFNSSKDNRQMNDKIDNKQDNKTEEVNYKIVGDGRETENHINKSKEIVDVK
                     QKLPKTGSNKIMELFLTVTGIGLLLTLKGLKYYGKDK"
     gene            67161..67457
                     /locus_tag="VXB91_000232"
     CDS             67161..67457
                     /locus_tag="VXB91_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0469748.1"
                     /translation="MVKINKICSIQGSSVENEDIVGSQNQYFWIIGGATDLYNSKEEI
                     GYSVSEVVHILSESLSVNCKESKTLKQIFETALLEVKDEIGLNSYELTEYNKMK"
BASE COUNT        19808 a        12419 c        15093 g        20145 t
ORIGIN      
        1 aaatattata gagccttata ttataattgt gttattttac ttccaactat tgagagaaat
       61 ttcgccacta tttagccaga tttcttttcc gttatcacat tgaactaaaa gttttccatt
      121 ttctgagatg tctttagcaa gtcccttgta gtctttttgc tgtagtgtga aagtgacttc
      181 ttttcctaga atgaatgact gttttttgta taggtataat agctcttctg ctggtgtttc
      241 gaagaaagca cgccagattt ctatgatcaa ttcattcctt gttataggag ctgtagcttt
      301 aaataagctg gcagcttttt cttttaattc ctgagggaag tctttaatag tgaaattgat
      361 acctactcca ataatgatat ctgtgactaa gccagtttct acagaggtca ttgcttcagt
      421 aaggattcct ccaattttat gattgtttag atagatatca ttgacccatt ttatgtcgac
      481 atctattaaa gttaggttct taatagcttt gtagacagct ccagctacaa gtagtgtgta
      541 ggatggtaat ttgtcatagg ggagatttgg tttaagatgg agtgtcatat aaataccacc
      601 ttgtggtgag tagaaggaac gttgaaaacg tcctcggcct gctgtttgat aggaagctag
      661 atagagggta tttgcttcat ggcctaaatc aattgcttct tttgcatcta gttgtgttga
      721 ttttgtttcg ggtttaaagc tgactttaat tggaagattt tcttctagaa tctctggaag
      781 aataaggtca ccattcatta gtttatatcc tctatttttg atactatcaa tttcaatgcc
      841 ttcttgttct agtcgcttga tagctttcca aattgatgtt cggcttaggg atagtttttc
      901 tgcgattttt tctccgctga tatagtcggt ttctttagat aggatttggt agacagcttg
      961 gtaggatttc ataatgttgc ctttctcact agttggtatt gagagtattc ttttcttgta
     1021 tgacttggag tctgattaaa gtattgttta taagctttcg aaaaatggag tggatctgaa
     1081 aaacctaccg agtatgcaat taccttgatg gactcttggg tattttcgag aagttgtcca
     1141 gctcggtgca ttcgaacgta gagtaggtat tctttgggtg ataaggtatt aaattctttg
     1201 aatacgcttg ataagtagct tctgtgaacg gatagttctt ttgctaaatc ttgaattgta
     1261 agtgattgag gatagtggct atcaattaat cgtttgcatt caagatagag ttggtgggtt
     1321 gatgaaatat tctttttttt ctgattggga gcaatagttc ccagatgaaa catcagttca
     1381 tgaagttgtc ccatgatatg gagttgagct aattcacttg attttgtaat ctgagcgaag
     1441 cggacaatgt ctgagatgag ttttgcagta gtctgggtat gacaagtttc agattggatg
     1501 agataggatt gatcagaaat ttgggaaaga gcaaaataat caggggcttt ccctccagtg
     1561 attcctaacc agtagtaggc ccaaggttct ttactatctg cttgataaaa ggttagttcc
     1621 tctggtttta atagaaagaa atctccttct tttaaatcaa caattttacc cttgtaatga
     1681 aattttcctt gtcctttagt aatgtaatgt agaacgtatg tatcacgaat ggctggacca
     1741 aaagagtaat taggtgtgca ttcctcatat ccataaaagc ttagggcaag gtcgattgtt
     1801 ccagtctggt attctgaaaa aactaacatg tgctacctcc tacctaacat tttaccatat
     1861 tcttgagaca tttttctatt ttggaaagcg atttcaggtg ataaaatata atcaataaag
     1921 tgatgaggtg aagtaaatgg gagttaggat agagaataat ctattttatg ttgagagtaa
     1981 aaatctaagt ttgattattg aaaatcgaaa tggctactta cttttgaaac atttaggaaa
     2041 gactattaag aactataaag gttccaatag tgtttatgaa cgagaccatg ccttttcagg
     2101 aaatccaacg gctactaatc gaacctttag tttagatact caacgtcaaa tttttggaca
     2161 acatggctta ggagatttta ggaaaccaac catacaggtt cagcataatg taactgaagt
     2221 aacagacttt cgatttgtag aagcaaagat tttaaaaggt cagaatggtc cacagggctt
     2281 accttctcca catagcatgg acgatacaga gactcttgtc ttaatgttag aagattctaa
     2341 ggctcaactt agtctgactt tgtattatac tacttttaat aatgatgcga ctattgctag
     2401 ctacagtaaa ttagataata atagtaatca ggaagttgtc atccataaag atttttcttt
     2461 tatggctgat tttccagctg cagattatga aatagcaact ctgcagggtg cttatgctcg
     2521 tgaaaagact gttagacgtc aacaggtaga acaaggaatc ttttcgatta gttcaaaccg
     2581 aggtgcttct ggtcatgctc aaacaccagc tcttctacta tgcgaacaag gagtcacaga
     2641 ggatgctggg aatgtgtttg ctattcaact aatgtatagt ggcaactttg aagcttttgt
     2701 tcaaaaaaat caattgaatg aagttcgggt ggctattggc attaatccag aaaacttttc
     2761 ttggaagtta gcccctgagg aatactttga aacaccggta gctttagtga ctcattcaga
     2821 tcagggatta actggtatta gtcatgaaag tcagaatttt gtactgaagc acattatgct
     2881 aagtgaattt tctaaaaaag aacgtccaat tctaatcaat aactgggaag ctacttactt
     2941 tgactttcag agagaaaaac tgttagagtt agcagatgaa gctaagaaag ttggcattga
     3001 actttttgta ttagatgatg gttggtttgg caatcgtttt gatgataatc gtgctttagg
     3061 tgattgggtt gttaatgagg aaaaactggg tggaagtcta gaaagtctga tttcagctat
     3121 ccatgaaaga ggtttgcagt ttggactttg gttagaaccc gaaatgattt ctgtagatag
     3181 tgatttgtat cgtcaacatc ctgactgggc tattcaggtt cctgattatg agcatactta
     3241 ttctcggaat caattagtac ttaatcttgc caatcctcag gtagtagaat acttgaaaag
     3301 tgtcttagat caactcctat cttatcatga gattgattac attaaatggg atatgaaccg
     3361 caatatcact aagctaggga atggattaac ttatctagag acacagatgc aatctcatca
     3421 gtacatgctg gggctttacg aactcgtttc ttatctgaca gagaagcaca gccatattct
     3481 ctttgagtcc tgctctggtg gtggtggacg aaatgatctt ggtatgatac gctatttccc
     3541 acaagtctgg gctagtgata atactgatgc cattgcacgt ttaccaattc aatacggttc
     3601 atcctatctc tatccaacca tttctatggg ggctcatgtg tcagcagtac cgaatcatca
     3661 gatgggacga atgacaccat tagaaacacg tggccatgta gcaatgatgg gaaatttggg
     3721 ctatgagctt gatttgacaa atttatcaga tgaagagaaa gctacgattg ctaatcaggt
     3781 gaacttgtat aaagaattac gaccagtagt tcagttagga cagcagtata gactaattaa
     3841 tcctgatact gcatccaatg aagcagctgt acaatttaat tacggaaatc aaacgattgt
     3901 aacctacgtt cgcgttttat ctgttgtaga gaccatggaa acaactttaa aattaaaaga
     3961 tttggatgaa gagggactat ataaattaca ggaaaatggc gaagtttact caggtgcaga
     4021 actaatgtat gcgggcttaa ctgttatctt atcccaagga gattttttga gtagacagta
     4081 tatttttaga aaactatgat atgtactgac cccaaaagtt agatttattc tgtctaactt
     4141 ttggggtgca gttcaataag ggtgtataaa tttataaagg aggctttcta atggaatggt
     4201 ataaaaaaat cggacttctt gcaactacag gtttagcttt gtttgggctc ggcgcttgct
     4261 ccaactatgg taaatctgcg gatggcacag tgaccatcga gtatttcaac cagaaaaaag
     4321 aaatgaccaa aaccttggaa gaaatcactc gtgattttga gaaggaaaac cctaagatca
     4381 aggtcaaagt cgtcaatgta ccaaatgctg gtgaagtatt gaagacacgc gttctcgcag
     4441 gagatgtgcc tgatgtggtc aatatttacc cacagtccat cgaactgcaa gaatgggcaa
     4501 aagcaggtgt ttttgaagat ttgagcaaca aagactacct gaaacgcgtg aaaaatgcct
     4561 acgctgaaaa atatgctgta aacgaaaaag tttataacgt tccttttaca gctaatgctt
     4621 atggaattta ctacaacaaa gataaattcg aagaactggg cttgaaggtt cctgaaacct
     4681 gggatgaatt tgaacagtta gtcaaagata tcgttgctaa aggacaaaca ccatttggaa
     4741 ttgcaggtgc agatgcctgg acactcaatg gttacaatca attagccttt gcgacagcaa
     4801 caggtggagg aaaagaagca aatcaatacc ttcgttattc tcaaccaaat gccattaaat
     4861 tgtcggatcc gattatgaaa gatgacatca aggtcatgga catccttcgc atcaatggct
     4921 ctaagcaaaa gaactgggaa ggtgctggct ataccgatgt tatcggagcc ttcgcacgtg
     4981 gggatgtcct catgacacca aatgggtctt gggcgatcac agcgattaat gaacaaaaac
     5041 cgaactttaa gattgggacc ttcatgattc caggaaaaga aaaaggacaa agcttaaccg
     5101 ttggtgcggg agacttggca tggtctatct cagccaccac caaacatcca aaagaagcca
     5161 atgcctttgt ggaatatatg acccgtccag aagtcatgca aaaatactac gatgtggacg
     5221 gatctccaac agcgatcgaa ggggtcaaac aagcaggaga agattcaccg cttgctggta
     5281 tgaccgaata tgcctttacg gatcgtcact tggtctggtt gcaacaatac tggaccagtg
     5341 aagcagactt ccataccttg accatgaact atgtcttgac cggtgataaa caaggcatgg
     5401 tcaatgattt gaatgccttc tttaacccga tgaaagcgga tgtggattag gagtagagag
     5461 actatgaaaa aagtattaca aaaatattgg gcatgggctt ttgtggtcat ccccctcttg
     5521 ttacaagcaa ttttcttcta tgtgccgatg tttcaaggag ccttttacag ttttaccaac
     5581 tggacaggat tgacttacaa ctacaaattt gtcggcttaa acaactttaa gctcctcttc
     5641 atggatccaa aattcatgaa tgcgattggc tttaccgcaa tcattacgat tgccatggtg
     5701 gttggtgaga ttgcactcgg gatcttcatt gcgcgtgtct tgaactctaa aatcaaaggc
     5761 caaaccttct tccgtgcttg gttcttcttc ccagctgttt tatctggttt gacagtggct
     5821 ttgatcttca agcaagtctt caactacggt cttccagcga ttgggaatgc ccttcatatt
     5881 gaatttctcc aaaccagtct tttagggact aagtggggag caatctttgc ggctgtcttt
     5941 gtccttcttt ggcaaggggt ggctatgccc atcatcatct tcctagctgg tttgcaatct
     6001 attccaactg agattacaga ggcagcaagg attgatggtg cgactagcaa gcaagttttc
     6061 tggaacattg aattgcctta cttgctacca agtgtctcta tggtctttat cctagcccta
     6121 aaaggtgggc tgactgcctt tgaccaagtc tttgccatga ccggtggtgg tccaaacaat
     6181 gccacaacct cacttgggct cttggtttat aactatgcct ttaaaaacaa ccaattcggt
     6241 tatgccaatg ccattgccgt aatcttgttc ctcttaattg tagtgatttc gatcatccaa
     6301 ttgagagtat ctaagaaatt tgaaatttaa gaggagaagc atgatgaaac aagatgaaag
     6361 aaaagccctg attggcaaat acattctatt gattctagga tcggttctga ttttagtgcc
     6421 gctccttgct accctcttta gttccttcaa acccactaag gatattgtag ataatttctt
     6481 tggctttcca accaacttca catgggacaa ctttagccgt ctcttagctg atgggattgg
     6541 aggctattat tggaactctg tcgtcatcac tgtcttgtct ttacttgcag taatgatctt
     6601 tatccctatg gcagcctact ccatcgctcg caatatgagt aaaagaaaag tctttaccat
     6661 catgtatacc ctcttaatcc tcggaatctt cgtacctttc caagtcatca tgattccgat
     6721 tacggttatg atgagtaaac tcggtttggc taataccttt ggtttgatct tgctctactt
     6781 gacctatgcg attccacaga ccctctttct ctatgttggc tatatcaaaa tctcgattcc
     6841 agaaagtctg gatgaagcag cagagatcga tggggctaat caatttacaa cctatttccg
     6901 catcatcttc ccaatgatga aaccgatgca tgcgacaacc atgatcatca atgccctttg
     6961 gttctggaat gacttcatgt tgccactcct tgtcttgaac cgggattcca aaatgtggac
     7021 tctgcctttg ttccaataca actacgcagg ccaatatttc aacgactacg gaccaagctt
     7081 tgcctcttac gtggtcggca ttatcagtat caccattgtc tatctcttct tccaacgcca
     7141 tatcatttca ggaatgagca acggggcagt gaagtaatac tcaatgaaaa tcaaagagca
     7201 aactaggaag ctagccgcag gttgctcaaa acactgtttt gaggttgtgg atgaaactga
     7261 cgaagtcagt aaccatacct acggtaaggt gaagctgacg tggtttgaag agattttcga
     7321 agagtataag aagagctcat ggaatctata gtctttgaca cagaggaaga gttcagcttg
     7381 ttgataattc tatgtagaaa acaagaaagt agtactttgt ttatcacagt ctatattagt
     7441 acgagtttga tgataaatag agatttaaaa tgaatttgat ttacgaagcc agatcatatg
     7501 agacttggct tcaattagaa aaaggagagt aatgatgcca attcaaaata aaaccatgtt
     7561 gattacctat tctgatagcc ttggaaataa tcttaaagac ttatatgata atttggaaga
     7621 gcattttgga gatgctattg gaggagttca ccttttacca tttttcccat caacaggtga
     7681 tcgtggattt gcgccagttg actacgacga agtggactca gcttttggtg attgggagga
     7741 tgttaagcgt ttaggtgaga aatattatct tatgtttgat tttatgatta atcatatttc
     7801 tcgtcaatcc aagtattata aggactatca agaaaaacat gaagccagtg aatttaaaga
     7861 tctcttttta aactgggata agttttggcc agaaaaccgt ccgacacagt ctgatgtaga
     7921 tttaatttac aagcgtaagg atcgtgcacc aaagcaagag attgtgtttg aagatggttc
     7981 agtggaacat ttgtggaata cctttggtga ggagcagatt gatcttgatg tgaccaaaga
     8041 agtaactatg gaatttatcc gtaagaccat tcagcacttg gcaagtaatg ggtgtgattt
     8101 gattcgtcta gatgcctttg cttatgcagt gaagaaattg gatactaatg atttctttgt
     8161 ggaaccagat atttgggatt tattggacaa agttcgagat atcgctgctg agtatgggac
     8221 agagctttta cctgagattc atgaacacta ttcgattcag tttaaaatag cagaccatga
     8281 ttactatgtt tatgattttg ctcttccaat ggtgacactt tatactcttt acagttccag
     8341 aacagagcgt ttggctaagt ggttaaagat gagcccgatg aagcaattta cgacgctaga
     8401 tacccatgat gggattggag tagtagatgt caaggatatc ctgaccgatg aggagattga
     8461 ctatgcttca aatgaactct ataaggttgg agccaatgtc aaacgtaagt actctagtgc
     8521 cgagtataac aacttagata tctaccaaat caattcaacc tactattcag cgcttggaga
     8581 tgatgatgtc aagtattttc tcgctcgtct aattcaagct tttgccccag gtattcctca
     8641 ggtttactat gtgggtctat tagcaggcaa gaatgacttg aaattattag aagaaactaa
     8701 agaaggtcga aatattaatc gtcattacta tagcaacgag gaaatagcaa aagaagtgca
     8761 acgacctgtt gtgaaggccc ttctcaatct attttctttc cgtaaccgtt cagaagcctt
     8821 tgatctagaa gggactactg agatagagac accaacagct cacagcattg taatcaaacg
     8881 tcaaaataaa gataagtccg taacagcagt agcagaaatt gacttgcaaa atcagactta
     8941 tcgggtaatt gagaatggag ttgaagtaac attttgaagc cttgatatgg tggataaaat
     9001 agggttttta ttttggaaaa cgtttccttt gttttcaaat tgctaaaaaa gtggtacaat
     9061 ataggatagc ttactattat ctgaatcagc tgatttggag agaaaggatt cattttgaaa
     9121 tcaataggct ttattgaaaa gctgaagggg ttgtctagta aagagctgat tttattggga
     9181 attatcctga gtatcttttt acccttttat ctttttgtag ttgtattctg tttatatatt
     9241 atcagtctga tttttacagg agacatgaaa agtattcttc agaaaatggg ggagcattcg
     9301 atgctgcttc tttttcttgg ctatagtact gttatatcca ttcttgcaca aaattggatg
     9361 ggtcttgtgg cttcagtagg aatgtttcta tttactattt tctttttgca ctatcagtcg
     9421 attttatccc ataaattctt tcgattgatt ttgcagttcg tcttgtttgg tagtgtcttg
     9481 tcagctgctt ttgccagttt agaacatttc caaattgtga agaaatttaa ctatgctttt
     9541 ctttccccca atatgcaggt gtggcatcag aaccgggcag aagtgacctt ctttaatcct
     9601 aattattatg gaattatttg ttgtttctgt attatgattg ctttctatct gtttacaacg
     9661 accaagttga attggttgaa agtattctgt gtgattgcag gctttgttaa tctctttggt
     9721 ttgaacttta ctcaaaatcg aactgccttt cctgctatta tcgctggagc aattatctat
     9781 ctctttacga ctattaaaaa ctggaaggcc ttttggctta gtattggggt cttcgcgatt
     9841 ggtttgagtt tcctcttttc tagtgatttg ggagttcgaa tgggtacttt agactcttct
     9901 atggaagaac gcatttctat ctgggatgct gggatggcct tgtttaagca aaatcctttt
     9961 tggggtgaag ggccattgac ctatatgcac tcttatcctc ggatacatgc tccttatcat
    10021 gaacatgccc acagtcttta tattgatacg attctgagtt acggaattgt gggtaccatt
    10081 ttattagttc tgtcttctgt tgctcctgtt cgcttgatga tggatatgag tcaggagtcg
    10141 gggaaacgtc cgattatcgg cctttatcta tctttcctta cagtggttgc tgtgcacgga
    10201 atttttgact tggctctctt ctggattcag tcaggcttta ttttcttgct agttatgtgc
    10261 agtattccat tggagcatcg aatgttggta tcggacatga cggattaagt tttataagtt
    10321 tgaaatcttc taccttgggt aggagatttt ttatacgatg ggcatgtcgt gcatctgagg
    10381 tgtaagtcct ctgtagggat ccactaccgg tgaatacaat agcgctcccc aagcctgact
    10441 atcgtgaggt agcggattaa aatggtctgg ggatagatcg ttttaagtct gacgcaggaa
    10501 ataagaattg tcagagaaag caatagtgaa atcgtaggct atgaatagaa acgtgatagc
    10561 gaggagcata tagtggataa ggtagcgaga aattttaaag tataaaagat agtcttaatc
    10621 tatatatgta aatcacaaaa gtaattgaat tcggaataag gttggtgtga aaagacatag
    10681 taaactgaat cttgaatact agaatgatac ttctacaata ttgttataat ttaatttgaa
    10741 ttccaaaatc acattgttcc gtccgtattt cattttactg tatgtcttcc taaactccaa
    10801 agtttctgcg tcaaatttcc tattttcact gtagtctttg acacttcgaa cgacaatttg
    10861 aatcatatat tcaaaaaaaa atgaaaaatt tgtgccaaca agcctaaata ttctgaaaat
    10921 ttgtttgatt tttaatggat aatgtgatat aatggttgtc aatctataat tcacataaac
    10981 agaggagtag aaaatgaaaa aaaatcgtgt atttgctaca gcaggtcttg ttttattagc
    11041 agcaggtgta cttgcagcat gcagttcttc aaaaacatct gattcatcag cccctaaagc
    11101 ttatggctat gtttatacag cagacccaga aaccttggac tacctgattt caagtaaaaa
    11161 tagtacaaca gtagtgactt caaatgggat tgatggttta ttcactaacg ataattacgg
    11221 taatcttgct cctgcagttg cagaggattg ggaagtctct aaggatggtt tgacctacac
    11281 ttataagatt cgtaaagggg ttaaatggtt tacctctgat ggagaagaat atgcagaggt
    11341 gacggctaaa gatttcgtga acggtttaaa acacgcagca gataaaaaat cagaagctat
    11401 gtatttagct gaaaattcgg ttaaaggctt ggcagattat ctatcaggaa cttcaacaga
    11461 tttttcaaca gttggtgtca aggcggttga tgattatacg ttacaataca ctttgaacca
    11521 gcctgaaccg ttctggaact ctaagttgac ctattctatt ttctggcctc tgaatgaaga
    11581 attcgaaaca tcaaaaggaa gcgattttgc taaaccaaca gatccgacat ccttgcttta
    11641 taatggtcca ttcttgttga aagggttgac tgcaaaatct tctgtagagt ttgtaaaaaa
    11701 tgagcaatat tgggataaag aaaatgtcca cctagatact atcaatctag cttactatga
    11761 tggatcagat caggagtcgc tagagcgtaa cttcactagt ggagcttata gttatgcccg
    11821 tctttaccct accagctcca actattctaa ggttgcagaa gaatacaagg acaatatcta
    11881 ttacacacaa tcaggctctg ggattgctgg tctgggtgtg aatattgatc gccaaagtta
    11941 caactatact tctaaaacta cagattcaga gaaagtagct actaagaagg cattgcttaa
    12001 caaagatttc cgtcaagcct tgaattttgc tcttgatcgc tcagcttact cagctcaaat
    12061 caatggtaaa gatggagcag ctttagcagt tcgtaattta tttgtaaaac cagactttgt
    12121 ttcagctggt gagaagacct ttggtgattt agtcgctgct caacttcctg cttatggtga
    12181 tgagtggaaa ggtgtgaatt tagctgatgg gcaggatggt ttattcaatg ctgacaaggc
    12241 caatgcagag tttgcgaaag ctaagaaagc tttagaagca gacggcgttc agtttcctat
    12301 tcatctggac gttccagtag accaagcatc aaaaaactat atatctcgta ttcagtcctt
    12361 taaacaatct gtagaaacag ttcttggtgt tgaaaatgtc gttgttgata ttcaacaaat
    12421 gacaagtgat gaattcctta atattactta ctatgctgcc aatgcttcat ctgaggattg
    12481 ggatgtatcg ggaggagttt catgggggcc agactatcaa gacccatcta cttacctgga
    12541 tattttaaaa acaactagca gtgaaactac aaaaacatat ttaggatttg ataatccaaa
    12601 tagcccttca gtagttcaag ttggtttgaa agaatacgat aaattagttg atgaagctgc
    12661 caaagagaca agcgacttga atgtccgtta tgaaaaatat gcagcggctc aagcatggtt
    12721 gacagatagt tcactcttta ttcctgctat ggcttcttct ggtgcagcac cagtgctttc
    12781 acgaattgtt ccatttactg gagcttctgc gcaaacaggc tctaaggggt cagatgttta
    12841 cttcaaatat ttgaaattac aagataaagc ggtgactaag gaagagtatg aaaaagctcg
    12901 tgaaaaatgg ttgaaagaaa aagctgaatc aaatgagaaa gctcaaaaag aattggcaag
    12961 tcatgtgaag taaataattt ctaatagaac tttctctcca tgaggagaag gttcttttgg
    13021 gatttttaaa ggaaataata tgaaaaaata tatttttatg cgtgttttgc ggtcattggt
    13081 ttcgattttc ttagtaacga ctttgaccta cacgattatc tataccttgg ttcctcgaaa
    13141 attgattttc aagcaggatc ctaactataa taaaattgcg acaacggctg ataaacgtga
    13201 taactatgaa aatactgtgt ttgagcgtat gggctacatt gagtattacg atactaaaga
    13261 gttgcaagaa aaggcaagta gcatggattc ttctgtaaca gtagaagcaa atgcgaccaa
    13321 taaagctatt tatgaaaagt acatcaatca attaggtcat ggttggactt tgggagaatt
    13381 tactgaaagt ggtcaattct atgctactcg tgaaattcca atttttgaac gtgtttttca
    13441 cttctatgct aacttgattg acattgacca tacaaataaa atccaagacc ctgaaaatcc
    13501 agacttgaaa cgctaccttc gttttgaaaa cgatccagct atcggatggt cattggtcgg
    13561 ttcaggaact aaacataaat atctcttgta ctttaacagt cagttcccat ttgttcatca
    13621 aaactttgtg aacttgaatt taggtgactc ttacccaacc tatgctaata caccagttct
    13681 tcaggttatt actcaaggtc aaggacaaac caaaactgcc caagttcagt tcccaacagg
    13741 taagaaaacg tcttctgtaa atatttactc aagaacctac aagtcaccta gtcaggctga
    13801 ctctcgtgaa gtagctagct atgggaaaga tgatccttat acagcgactg aaagtaatta
    13861 ccaatatcca tctatgattg tcagctctgc tattactggt ttgattggtt tggttcttgc
    13921 ctatgctctt gccgtgccac ttggttcagc catggctcgt ttcaagaaca cttggattga
    13981 tagcctctca acaggggctt tgaccttctt gcttgctctt ccaacgattg ccttggttta
    14041 catcgttcga ttgattggat catctatttc ccttccagat tcattcccta tcttgggagc
    14101 tggagattgg cgttcttacg ttttaccagc agtcatcctt ggtttgttgg gtgctcctgg
    14161 tacagccatt tggattcgtc gttacatgat tgacttgcaa tctcaagact ttgttcgttt
    14221 cgctcgtgca aaaggtttgt ctgaaaaaga aatttcaaac aaacacatct ttaaaaatgc
    14281 catggttccg ctggtttcag gaattcctgg tgccattatt ggggttatcg gtggtgcaac
    14341 ccttactgaa acagtcttcg ccttcccagg tatgggtaaa atgttgattg actctgtaaa
    14401 agcatctaat aactctatgg tcgttggtct tgtcttcatc tttacatgta tttctatctt
    14461 ctcacgtctt ttgggagata tttggatgac tattattgac ccacgtatta aattgactga
    14521 gaaaggaggc aaataatgtc tacaatcgat aaagaaaaat ttcagtttgt aaaacgtgac
    14581 gattttgcct ctgaaactat tgatgcgcca gcatattctt actggaaatc agtgtttaaa
    14641 caatttatga agaaaaaatc aactgtagtc atgttgggaa tcttggtagc catcattttg
    14701 ataagtttca tctacccaat gttttctaag tttgatttca atgatgtcag caaggtaaac
    14761 gactttagtg ttcgttatat caagccaaat gcggagcatt ggttcggtac tgacagtaac
    14821 ggtaaatcgc tctttgacgg tgtctggttc ggagctcgta actccatcct catttctgtg
    14881 attgcgacag tgattaactt ggttatcggt gtttttgtcg gtggtatttg gggtatttca
    14941 aaatcagttg accgtgtcat gatggaagtt tacaacgtca tctcaaacat cccacctctt
    15001 ttgattgtta ttgtcttgac ttactcaatc ggagctggat tctggaatct gatttttgcc
    15061 atgagcgtaa caacatggat tggtattgcc ttcatgatcc gtgtgcaaat cttgcgctat
    15121 cgtgacttgg aatacaactt ggcgtcacgt actttgggaa caccaacctt gaagattgtt
    15181 gccaaaaata tcatgcctca attggtatct gttattgtga caaccatgac tcaaatgctt
    15241 ccaagcttta tctcatacga agccttcttg tctttcttcg gtcttggatt accgattaca
    15301 gtgccaagtt tgggtcgttt gatttcggat tattcacaaa acgtaacaac caatgcttac
    15361 ttgttctgga ttccattgac aacccttgtc ttggtatcct tgtccctttt cgtagttggt
    15421 caaaacttag cggatgctag tgatccacgt acacatagat aggagtagaa atgacaaaag
    15481 aaaaaaatgt aattttgact gctcgcgata ttgtcgtgga atttgacgtt cgtgacaaag
    15541 tattgacagc cattcgcggc gtttcccttg aactagtcga aggagaagta ttagccttgg
    15601 taggtgagtc aggatcaggt aaatctgttt tgacaaagac cttcacaggt atgctcgaag
    15661 aaaatggtcg cattgcccaa ggtagtattg actaccgtgg tcaggacttg acagctttat
    15721 cttctcacaa ggattgggaa caaattcgtg gtgctaagat tgcgactatc ttccaggacc
    15781 caatgactag tttggacccc attaaaacaa ttggtagtca gattacagaa gttattgtaa
    15841 aacaccaagg aaaaacagct aaagaagcga aagaattggc cattgactac atgaataagg
    15901 ttggcattcc agacgcagat agacgtttta atgaataccc attccaatat tctggaggaa
    15961 tgcgtcaacg tatcgttatt gcgattgccc ttgcctgccg acctgatgtc ttgatctgtg
    16021 atgagccaac aactgccttg gatgtaacta ttcaagctca gattattgat ttgctaaaat
    16081 ctttacaaaa cgagtatcat ttcacaacaa tctttattac ccacgacctt ggtgtggtgg
    16141 caagtattgc ggataaggta gcggttatgt atgcaggaga aatcgttgag tatggaacgg
    16201 ttgaggaagt cttctatgac cctcgccatc catatacatg gagtctcttg tctagcttgc
    16261 ctcagcttgc tgatgataaa ggggatcttt actcaatccc aggaacacct ccgtcacttt
    16321 atactgacct gaaaggggat gcttttgctt tgcgttctga ctacgcaatg cagattgact
    16381 tcgaacaaaa agctcctcaa ttctcagtat caaagacaca ttgggctaaa acttggcttc
    16441 ttcatgagga tgctccaaaa gtagaaaaac cagctgtgat tgcaaatctc catgataaga
    16501 tccgtgaaaa aatgggattt gcccatctgg ctgactagga ggaaggaaat gtctgaaaaa
    16561 ttagtagaaa tcaaagattt agaaatttcc ttcggtgaag gaagtaagaa gtttgtcgcg
    16621 gttaaaaatg ctaacttctt tatcaacaag ggagaaactt tctcgcttgt aggtgagtcc
    16681 ggtagtggga aaacaactat tggtcgtgct atcatcggtc taaatgatac aagtaatgga
    16741 gatatcattt ttgatggtca aaagattaat ggtaagaaat cgcgtgaaca agctgcggaa
    16801 ttgattcgtc gaatccagat gattttccaa gaccctgccg caagtttgaa tgaacgtgcg
    16861 actgttgatt atattatttc tgaaggtctt tacaatcacc gtttatttaa ggatgaagaa
    16921 gaacgtaaag agaaagttca aaatattatc cgtgaagtag gtcttcttgc tgagcacttg
    16981 actcgttacc ctcatgaatt ctcaggcggt caacgtcaac gtatcggtat tgcccgtgcc
    17041 ttggtcatgc aaccagactt tgttattgca gatgagccaa tttcagcctt ggacgtttct
    17101 gtacgtgccc aagtcttgaa cttgctcaaa aaattccaaa aagagctcgg cctgacctat
    17161 ctcttcatcg cccatgactt gtcggttgtt cgctttattt cagatcgtat cgcagttatt
    17221 tacaagggtg ttattgtaga ggttgcagaa acagaagaat tgtttaacaa tccaattcac
    17281 ccatatactc aagccttgct ttcagcggta ccaatcccag atccaatctt ggaacgtaag
    17341 aaggtcttga aggtttacga cccaagtcaa cacgactatg agactgataa gccatctatg
    17401 gtagaaatcc gtccaggtca ctatgtttgg gcgaaccaag ccgaattggc acgttatcaa
    17461 aaaggactaa actagtaatg gttttataat ttccatgtca atttttatgg aaattataaa
    17521 actttttttg ttggactgat ttgaaaaact ttgaaagctt cctgaaagaa tttttgaaaa
    17581 attttaaaaa ttatgaaatg ttattgacag gtgatgaaaa aggtggtagg acaggaagca
    17641 tcaaaaaaga aagcagaaaa agaaatgaat aagagacaag ccgtaactat gaatcaaaac
    17701 ttttacttta gctactttag atagtgtttg tagacatgtc accatggatg caaacagttc
    17761 aagcaatttg tttgtatcta tgtggctaag atttttgatt gtggtccata tagatgaata
    17821 tctaaatgga ctagctaagt tgtaacttgt taggttattt caagtatccg tttagatagt
    17881 atctaggcgg ttttttgttt tatcttttct gagaaggagt ttcattatga aagttgttcg
    17941 aaaatcacta gccccctctt ggtagtgggg ctcctcttga cttctctgat cagtttgcat
    18001 cagttgaagg cagataagaa aaagatgtct ttcgtatcgg tatttcgcaa tttattaccc
    18061 accagtcctt atacgctact agagaaggat ttgtggatga gctggccaaa caaggctatg
    18121 ttgaggggga aaatattgag attgatttgc aaaatgcaca gggagaacaa agaaatctaa
    18181 aaacgatttc ccagcaacta gcagaatcca gcgatgtcgt tctagccatc gcaaggcctt
    18241 ctgctcagag cttggccaat acgacgcaaa cgacaccagt tatcttttca gctgtaacag
    18301 acccagtcag tgccaagttg gttgagtcaa gagaacatcc tgggggcaat gtaactggga
    18361 caagcgatca gtcatcagat gccatttcaa cccaaatcaa tttgataaag aaagtgttgc
    18421 caaaggctaa aacgattgga atcctctata ctcagagcga gcccaattcg gttgttcaaa
    18481 aggatgaagc taagcgactt ctgaaagaaa aaggctttac cgttgttgaa aaaacaatct
    18541 tggacagtaa taacgtcaag gcggcagcag agagtttgat ggcagaggtg gatatggttt
    18601 ttgtcccaac tgataatatc atttcgttaa ccatggaaac agttaagcag gtttctatta
    18661 aacacaaggt tccagtattc ggtggttcaa cagaaatgat tgctgttggt ggcttgtata
    18721 actacggaac caattatgaa gaattggtac gtcagacagc tcgcatgctg attcgtgttt
    18781 taaaaggtga gaaaccagaa aatatagcag ttgagttgcc tgaaaaactg gaattgcata
    18841 ccaatcaaga aatggcagat gcattgggaa ttgatattag taagttagaa ggcaaggaat
    18901 aaggaggatt aagatgaatt ttgtgttatc tagtttatca gaaggtttgt tgtggtcgat
    18961 tgtggcgatt ggggtctact tgactttccg tattttggat attgcggata tgactgctga
    19021 gggagccttt cctctggggg cagcagtcgt tgtatcacag atacaggcag gggcaaatcc
    19081 ttggcttgcg actttacttg ctttgctggc aggtatggta gcaggtcttg tatcaggaat
    19141 gctccacacc aagatgaaaa tcccagctct cttgacaggg attgtgacct tgacagggct
    19201 ctattcaatc aatattaaaa tcatgggcag tgtacccaat ctttccttgg gagattctgc
    19261 aaccgtcttt aaacagttgg cgagcttggg tctgacaaat gaaggaactg ttttctcact
    19321 tagtttggcc tgttttttac ttgtttgttt ggtcttgacc cttttgatga aaacagagat
    19381 tggcctggtc ttgcgttcga ctggggataa tatcccgatg agtgaggcca atggagtcaa
    19441 tgtagacacc atgaagattg ttggttacat gatttcaaac ggtttgattg ctctatgtgg
    19501 ttccttgttt gcccaaaatg atggattttc agatgtgact tctgggacag gaaccattgt
    19561 tgttggtttg agctcggtga ttattgcgga agtcttgata cacgacttga ccattggagg
    19621 ccgcttatta tccatcggaa tcggtgctat tgtttaccgt ttgattattt taaatatcta
    19681 tgaaattcca aatctagatc aaaacttggt acgtctcttt aatgcaatct tgctcgcttt
    19741 ggttttattt gcaccagaat tgcaaaagag attaaagatt cgtggtctga aattgagaaa
    19801 tgaataggag gagaaagtta tgacaagttt gttaacactt gaaaatattc acaagacatt
    19861 tgaagcaggg acggtcaatg agaaccatgt cctcaaagga ttagatttag aggttgaaga
    19921 gggagatttt atctctgtga ttggtggaaa tggagcagga aaatccactt tgatgaatat
    19981 cttggctggc aatctatcgg tggacgaagg ggaccttcta ctggcaggga aatccattaa
    20041 aaatctgagt gtcagaaaga gagccaagga tattgcccgt gtttttcaag atcctaagat
    20101 gggaacagct tctcgtttga cgattgagga gaatatggct attgccttga gacgcgggca
    20161 gaagagaggg cttggttggg gcgtgaagga gaaggataga atccagttcc aagaggcctt
    20221 gaaggagttg aatattggtc ttgaaaaccg cttaaaagta gatactcaat atctctcagg
    20281 aggacaaaga caggctttga ctctagtcat gacagatctg atgaaaccaa aacttttact
    20341 tttggatgaa catactgcgg cacttgaccc gaaaaccagt caaatggtga tggacttgac
    20401 gcaaaagatt gtggagcacc atcagtggac gactttgatg attacccatg atatgaatca
    20461 tgcgattgag tacggcaatc gtctcattat gctctatcaa ggcaagatag tggtggatgt
    20521 caagggagaa gagaaaaagc atctgacagt tgaagacctt atgcatctct tccagaaaaa
    20581 tagtggccaa agtctggtca gtgatgaatt agttttggga taaagaaaaa ggctgagatc
    20641 tggtgtctca gtcttttatt tcttgcgttt tgcaaaatct acaaatctaa atttctctaa
    20701 cttatggcga ctttcggtaa actgaaattg gcgtccgtct tggagataga cttttgattt
    20761 aatcgaaacg acataagggt ctttgccaat gtccatgaga atcttgtctc ggtcgcttga
    20821 gtggtcaatg gtgatttcct tctgagcata atcaataagg agtttgaggc cattttctat
    20881 ataagaatag atagactgct cagcaatttg gcgagtgaga tttggaatta gttccatatc
    20941 cagatagtcc gtatccagaa cggataccag atcatccacc acacgctggc ggaccacctt
    21001 ccaaaccatc cgaaactctg ggaaaccggt tatcagtgag gattttttat caataataat
    21061 cttgtccaga ctgaccacgt tggttttaga gcgcagtcca agttctttaa ctagttcttg
    21121 gtagctggtt aggttggata cagggaaatt gacggtttct tctttgacga cttgagaacc
    21181 ttgctctctt atctttttga tcaatccttc ctcttggagg agagacaggg cctttcggac
    21241 ggtatcacga ctcacttgat attgctccat aaggtcgtgc tcgctaggaa ggaaatctcc
    21301 gacagcgtaa gtctcgtttt gaatggtttc ttggatttgc ttaaataatt gttggtattt
    21361 cttcattttg cctgctttaa taggttttta gtctagttta atgaacacct gtatctattt
    21421 taccatacaa gtgctagaaa atttacaaaa aaacaccctt tttataccaa acaagttgca
    21481 gacaagtttg gtatcgttta caatatactt atcaaatcaa acttgctttg acaagtataa
    21541 ggagaatcaa atgggaaaat ttgaacaaga agccaaagat ctgcttcagg caattggagg
    21601 caaagaaaat gtgactgccg taactcactg tgcgacacgg atgcgctttg ttttaggaga
    21661 tgataagaag gctaatgtta aagctatcga gtcaattcca gctgttaaag gaacttttac
    21721 aaatgcaggt caatttcagg taatcattgg aaatgacgtg cccatctttt ataatgattt
    21781 tacagccgtt tcaggtattg agggtgtttc caaagaagca gccaagtctg cagctaagag
    21841 taatcaaaac gtggtccaac gtgttatgac cactctggcg gagattttta ctccgattat
    21901 tccagccttg atagtcggag gattgatcct cggtttccgt aatgtcttgg aaggtgtcca
    21961 ttggtcgatg ttggatggca agaccatcac agaatcctct cagttttggg caggtgtcaa
    22021 tcacttcctc tggttgcctg gtgaagctat cttccagttc ttaccagtag ggattacttg
    22081 gtctgtttct cgtaagatgg gaaccagcca aattttggga attgttctcg gaatctgttt
    22141 ggtatcgcct cagttgctca atgcctatgc ggttgcttca acgccagcag ctgatatcgc
    22201 ggcaaactgg gtttggaatt ttggctattt tactgttaat cgtatcggtt accaagccca
    22261 agttatccca gccttgcttg caggtttgag tctgtcttat cttgaaatct tctggcgcaa
    22321 gcatatccca gaagtcattt ctatgatttt tgtacctttc ttgtcattga ttccagcctt
    22381 gattttggct catactgttt tgggaccaat cggttggaca attggacaag gactttcatc
    22441 agttgtcttg gcaggtttaa ctggtccagt taaagggctc ttcggtgcaa tttttggtgc
    22501 cctctacgct ccatttgtca tcacaggtct gcaccatatg accaatgcca ttgatacaca
    22561 attgattgcg gatgctggtg gcactgccct atggccaatg attgctcttt ctaatattgc
    22621 tcaaggctca gccgtgtttg cctattattt catgcatcgc catgatgagc gtgaggctca
    22681 ggtttcactt cctgcaacca tttcagccta tctcggtgtt acagaaccag ctctttttgg
    22741 ggttaacgta aaatatattt atccatttgt tgctgggatg actggttcag cccttgcagg
    22801 catgttatcc gttactttta atgtaactgc ggcttctatt ggtatcggtg gtttgccagg
    22861 tattctctct attcaacctc aatacatgct gccatttgca ggaactatgc tagttgcgat
    22921 tgttgttcca atgctcttga ctttcttctt ccgcaaggct ggtctcttta caaaaacaga
    22981 gggcgatacg aacttgcagg cagaattcgt tgctcaagaa gaagcagaat ttgtgaacca
    23041 tgaaccagta gaacttactt cggtagaaat tatcagccca ctaactggcc aagtgaaaga
    23101 attgagtcaa gcgacggatc ctatttttgc atcaggtgtc atggggcaag gtctggtcat
    23161 tgaaccaagc caaggtgagt tgacctctcc agttaatggg acagtgacgg ttcttttccc
    23221 taccaagcat gccatcggca ttgtctctga cgagggagtt gaattgctca tccacatcgg
    23281 tatggataca gtaggtcttg atggcaaagg ttttgaaagt cttgtagtcc aaggagatca
    23341 cgttacagtt ggtcagcaac tgattcgttt tgatatggat gtcattaagg ctgcaggtct
    23401 ggtgacagaa actcctgtta tcatcaccaa ccaagatgct tatacagcga ctattcccgg
    23461 aacttatccg acaacgattc aagctggagc atctctcatg gtcgctacac gaatctaata
    23521 ctcttcgaaa atctcttcaa accacgtcag ctctatctgc aacctcaaaa cagtgttttg
    23581 agcaacctgt ggctagcttc ctagtttgct ctttgatttt cattgagtat aattgaaata
    23641 gcacaaatag ggacggaaga ctgcttcctc ccttttatca gaaaaggaga aacagatgac
    23701 acttgataaa ggaaaagtag tctatcaaat ctatccaaaa tcttacaaag acaccactga
    23761 aaacggtatt ggggatttcc gtgggattat cgaaaaaatt ccctatttag ccaaactagg
    23821 cgtggatatg gtctggctca atccattcta tccaagccct caacgggata atggttacga
    23881 tatttcagat tatatggcag tggatcctct ttttggtgat atggctgatt ttgaggaaat
    23941 ggtgtgtgtc ggtaaagagc acaagattga ctttatgctg gacatggtac ttaatcattg
    24001 ttcgacagag catgaatggt ttcagaaagc cctagctggt gataagtatt atcaagactt
    24061 tttcttcatc caagaccaac caacagattg gcagtctaag tttggtggtt ctgcatgggc
    24121 gcctttcggg gatactggga aatactatct tcacctattt gatgagaccc aggctgacct
    24181 taactggcgc aattccaatg tccgtaagga gcttttcaag gttgttaatt tctggcgcga
    24241 caagggtgtc aaaggtttcc gatttgatgt gatcaatttg atcggtaagg acgaggtttc
    24301 agtggactgt cctgaaaatg aagggaagcc agcttataca gacaaaccca tcgttcataa
    24361 ctatttgcgt atgatgaacc aagccacttt tggatctgac gatagcttta tgacagttgg
    24421 ggaaatgtct tctaccacca tggaaaactg tgtcctctat tcgtcgcctg atcgtcagga
    24481 attatccatg acctttaatt ttcatcacct caaggtggac tataaggatg gacaaaagtg
    24541 gaccttggct ccctttgatt ttgaagagtt gaagagtctt taccatagtt ggggtaagga
    24601 aatgagtgat aaagacggtt ggagtgccct cttttggaac aatcacgatc aaccacgtgc
    24661 cttgaaccgt tttgtcgata ttcaaaactt ccgcaaggaa ggagccacca tgctagcagc
    24721 cagcattcac ctgtcacgtg ggacacctta tatctacatg ggtgaggaaa tcgggatgat
    24781 tgacccagac tatgattcta tggctgatta tgtggatgtc gaatcgctta atgcctatca
    24841 gatgctctta gaagaaggaa agagtcagca agaagccttc cagattattc aagctaagtc
    24901 gcgtgataat tcacgtattc ccatgcagtg ggatacttct gaaaatgcag gattttcaac
    24961 aggcactcca tggttgaaag tcggtaaatc ctataaagat atcaatgtag aaaatgaaat
    25021 caaaggtctg attttcacct tctatcaaga cttgattcga ctgcgtaagg aaatgccaat
    25081 catttcagaa ggaaattaca aaccagcctt tgaagatagc aaacaagtct acgcttttga
    25141 acgccagttt gaggatcaaa agttactagt gctcaataac ttttatgcca aagaagtgga
    25201 aatcgacttg ccagcagtct accaaaatgg acagattttg atttcaaact atgaagatgc
    25261 agaagtgtct gagaaaattc tactcaaacc ctatcaaaca ctggctattt atgtaaatta
    25321 atactcttcg aaaatctctt caaaccgtgt cagttttatc tgtaacctca aagcggtgct
    25381 ttgagcaacc tgtggctagc ttcctagttt gctctttgat tttcattgag tataaactta
    25441 gcaaggagac ctctttttca gaaaagcagg gttctttttg ctgtctattc catccttgaa
    25501 agtgtagaac aaactggtca gggtggctag tttgtggtat aatgaaaggg attcaaaaag
    25561 aaacaggaga aaaatgatgg atttactttt agcaattgta ttgattgtgc tagcttttct
    25621 aggaggagct cttggaggaa tgtacttggt tcgtaagcaa atcgaaaaag aatttgctga
    25681 caacccacgt ttgaatgctg aagcagttcg tactcttttg agtgcaaatg gtcaaaaacc
    25741 aagcgaagct aaggtacaac aagtttacca ccaaatcatc cgccaacaaa aggcagccct
    25801 tgctaacaat aaaaagaaaa aataaataag gaaaagtctg ggatgaaagt tccagacttc
    25861 tcactatgtt ggttatggtt tagggatgag actttttcct tgcattctat tgatatttga
    25921 ttatgattaa gagagaggta gttgacattc tatcaagctg tcggtcagtt cgttcagtac
    25981 aaggaatcat aatgaacgat caatcagaaa aaagactaga aagaagactg tatggataat
    26041 cgaccaattg gttttttgga ttcgggtgtc gggggcttga ccgttgtgcg cgagctcatg
    26101 cgccagcttc cccatgaaga aatcgtctat attggagatt cggcgcgggc gccctatggc
    26161 ccccgtcctg ctgagcaaat tcgtgaatat acttggcagc tggtcaactt tctcttgacc
    26221 aaggatgtca aaatgattgt cattgcttgt aacactgcga ctgcggtcgt ctgggaagaa
    26281 atcaaggctc aactagatat tcctgtcttg ggtgtaattt tgccaggagc ttcggcagcc
    26341 atcaagtcca gtcaaggtgg gaaaatcgga gtgattggaa cgcccatgac ggtacaatca
    26401 gacatatacc gtcagaaaat ccatgatctg gatcccgact tacaggtgga gagcttggcc
    26461 tgtcccaagt ttgctccctt ggttgagtca ggtgccctgt caaccagtgt taccaagaag
    26521 gtggtctatg aaaccctgcg tcccttggtt ggaaaggtgg atagcctgat tttgggctgt
    26581 actcattatc cactccttcg ccctattatc caaaatgtga tggggccaaa ggttcagctc
    26641 atcgatagtg gggcagagtg cgtacgggat atctcagtct tactcaatta ttttgaaatc
    26701 aatcgtggtc gcgatgctgg accactccat caccgttttt acacaacagc cagtagccaa
    26761 agttttgcac aaattggtga agaatggctg gaaaaagaga ttcatgtgga gcatgtagaa
    26821 ttatgacaaa taaaatttat gaatataagg atgaccagga ctggtatgtt gggtcttata
    26881 gtatttttgg tggcgttaac agtttgagcg actataagac agattttcct ctgtttgaat
    26941 tctccaaaat atttggagat gaagagtatg gtttcccgct ttcagttact gttttacgct
    27001 atggttctac ctaccgtttg ttctcctttg tggtagacat gcttaatcaa gaaatgggac
    27061 gaaacttgga agttattcaa cgtcatgggg ccctgctctt ggttgaaaat gggcaactct
    27121 tgtatgtaga attgcctaaa gaaggggtca atgttcatga tttctttgag acaagcaagg
    27181 tcagagaaac cttgttgatt gcgactcgta acgaaggtaa aaccaaggaa ttccgagcta
    27241 tctttgataa gttaggctac gatgtggaaa atcttaatga ctaccctgac ctgcctgaag
    27301 tagcagaaac aggtatgacc tttgaagaaa atgcccgcct taaggcagaa accatttctc
    27361 aattaacggg caagatggtt ttggcagatg attctggtct caaagtcgat gtccttggtg
    27421 gcttaccagg cgtctggtca gctcgtttcg caggtgtggg agcaactgac cgtgaaaata
    27481 atgccaaact cttgcacgaa ttggccatgg tctttgaact caaggaccgc tcggctcagt
    27541 tccacacaac cctagtcgta gccagcccaa ataaggaaag tttagttgtt gaagcagact
    27601 ggtcaggtta tattaacttt gaacctaagg gtgaaaatgg ctttggctat gatcccctct
    27661 tccttgtagg agagacaggt gagtcatcag ctgaattaac cctagaagaa aaaaatagtc
    27721 aatctcaccg tgccttagcc gttaagaaac ttttggaggt atttccatca tggcaaagca
    27781 aaccatcatt gtaatgagcg attcccatgg cgatagcttg attgtggaag aagtccgtga
    27841 tcgctatgtg ggcaaagtcg atgccgtttt tcataacggc gattctgaac tacgtccgga
    27901 ttctccactt tgggagggca tccgcgttgt taaagggaac atggacttct acgccggcta
    27961 cccagaacgt ctggtgactg agcttggttc gaccaagatt atccaaactc atggtcactt
    28021 gtttgacatc aatttcaact ttcaaaagtt ggactactgg gctcaggagg aagaggccgc
    28081 tatctgcctc tatggtcact tgcatgtgcc aagtgcttgg ttggaaggca agatcctctt
    28141 tctaaatcca ggttctatca gtcaaccacg aggtaccatc agagaatgtc tctatgctcg
    28201 tgtggagatt gatgatagtt acttcaaagt ggactttttg acacgagatc acgaggtgta
    28261 tccaggtttg tccaaggagt ttagccgatg attgccaagg agtttgagac tttcttgttg
    28321 gggcaggagg aaactttttt gacccctgct aaaaatctag ctgtgttgat tgatacccac
    28381 aatgcggatc atgcgaccct cttgctcagt cagatgacct atacccgtgt tcccgttgtg
    28441 acagatgaaa aacagtttgt tgggacgatt ggactcagag atattatggc ttatcagatg
    28501 gagcatgact tgagccaaga aatcatggcg gatacggata tcgttcatat gacaaaaacg
    28561 gacgtagcgg ttgtttcgcc tgatttcacc attacggagg tcttgcacaa gctagtagat
    28621 gagtccttct taccggtcgt ggatgcagag ggtattttcc aagggattat tacgcgcaag
    28681 tccatcctca aggccgttaa tgccctcttg catgacttta gtaaggaata tgagattcga
    28741 tgccaatgag agacaggatt tcagcctttt tagaggaaaa gcagggcttg tctgtcaatt
    28801 ccaagcagtc ctataagtat gatttggagc aatttttaga catggtaggt gagcggattt
    28861 ctgagaccag tctcaagatt taccaagccc agctagccaa tctaaaaatc agcgcccaga
    28921 agcgaaagat ttcggcctgt aaccaatttc tatactttct ctatcaaaaa ggagaggtgg
    28981 acagctttta ccgcttggaa ttagccaaac aagctgaaaa gaagacggaa aagccagaga
    29041 ttctatacct agactctttt tggcaggaaa gcgaccatcc agagggccgc ttgctagcgc
    29101 tcttaatcct agaaatgggg ctcttgccca gtgagatttt agccatcaag gttgcggaca
    29161 tcaatctgga ttttcaggtg ctgcgaatca gcaaggcttc ccaacagagg attgtcacca
    29221 ttcccacggc cttgctttca gaattggaac ccttgatggg gcagacctat ctttttgaaa
    29281 gaggagagaa accctattct cgtcagtggg cctttcgtca gttagaatct tttgtcaagg
    29341 agaaaggttt tccatcctta tcagctcaag tcttacgtga acagtttatt ctaagacaaa
    29401 tagaaaacaa ggtcgatttg tacgaaattg caaaaaaatt aggattaaaa acagtcctga
    29461 ccttagaaaa atatagataa tggatattaa attaaaagat tttgaaggac ccctggactt
    29521 gctcttgcat ctggtttcta agtaccagat ggatatctac gatgtgccca ttacggaagt
    29581 catcgaacag tatctagcct atgtctcaac cctgcaggcc atgcgtctgg aagtgacggg
    29641 tgagtacatg gtcatggcta gtcagctcat gctgattaag agtcgtaaac tccttccgaa
    29701 ggtagcagaa gtgacagact tgggggatga cctggagcag gacctcctct ctcaaatcga
    29761 agaatatcgc aagttcaagc tcttgggtga gcacttggaa gccaagcacc aagaacgggc
    29821 ccagtattat tccaaagcgc cgacagagtt gatttacgaa gatgcggagc ttgtgcatga
    29881 caagacgacc attgacctct ttttggcttt ttcaaatatc ctagccaaga aaaaagagga
    29941 gtttgcacaa aatcacacga cgatcttgcg ggatgagtat aagattgagg acatgatgat
    30001 tatcgtgaaa gagtccttga ttggacgaga tcaattgcgc ttgcaggatt tgttcaagga
    30061 agcccagaat gtccaagagg tcatcaccct ctttttggca accctagagt taatcaaaac
    30121 ccaggagctg atcctcgtgc aagaggagag ttttggagat atctatctca tggaaaagaa
    30181 ggaagaaagt caagtgcctc aaagctagac ttgatagaga ggaaagatga gtactttagc
    30241 aaaaatagaa gcgctcttgt ttgtagcggg tgaagatggg attcgggtcc gccagttagc
    30301 tgaactcctc tctctgccac cgacaggcat ccagcaaagt ttaggaaaat tagcccagaa
    30361 gtatgaaaag gacccagatt ccagtttggc tttgattgag acaagtggtg cttatagatt
    30421 ggtgaccaag cctcaatttg cagagatttt gaaggaatac tctaaggcgc ctatcaacca
    30481 gagcttgtct cgggctgccc ttgagacctt gtccattatt gcctacaaac agccgattac
    30541 gcggatagaa attgatgcca tccgtggagt taactcgagt ggagccttgg caaagttgca
    30601 ggcttttgac ctgataaagg aagacgggaa aaaggaagta ttggggcgcc ccaacctcta
    30661 tgtgactacg gattatttcc tagattacat ggggataaac catttagaag aattaccagt
    30721 gattgatgag cttgagattc aagcccaaga aagccaatta tttggtgaaa ggatagaaga
    30781 agatgagaat caataagtat attgcccacg caggtgtggc cagtaggaga aaagcagaag
    30841 agctgattaa gcaaggcttg gtgacggtta acggccaagt ggtgcgtgaa ctagcaacca
    30901 ctatcaagtc aggcgacaag gtcgaagttg aaggtcaacc tatctacaac gaagaaaagg
    30961 tctactatct gcttaacaaa ccacgcggtg tgatttccag tgtgacagat gataagggtc
    31021 gcaagacggt tgtcgacctc ttgcccaatg tcaaagagcg tatttaccct gtgggtcgtt
    31081 tggactggga tacatcaggt gtcttgattt tgaccaatga tggggacttt acagacgaga
    31141 tgattcaccc tcgtaatgag attgacaagg tttatgtcgc gcgtgttaaa ggtgtggcca
    31201 ataaggacaa tctccgcccc ttgacccgtg gtcttgagat tgatggtaag aaaaccaagc
    31261 cagctgttta tgaaattctc aaagtggacc cagtcaaaaa tcgctctgtg gtgcagttga
    31321 ccatccatga agggcgtaac catcaggtta aaaagatgtt tgaagctgtt ggtctccaag
    31381 tagataagtt gtctcggact cgtttcggac acctagactt gacaggactc cgtccaggag
    31441 aatcccgtcg tcttaataaa aaagaaatca gccaactaca caccatggct gtaactaaga
    31501 aataatgaaa cgaattttaa tagcgcctgt gcgcttttac caacgtttta tctcaccagt
    31561 ctttccaccc tcttgtcgct ttgagctgac ttgttccaac tacatgattc aggctattga
    31621 aaaacatggt tttaaggggg tattgatggg cttggctcgg attttacgtt gtcatccctg
    31681 gtcgaaaaca ggtaaggacc ccgttccaga ccacttttcc cttaaacgaa atcaagaagg
    31741 ggaatgaggt ggggtaaata gatttcaaaa tgataaaaac gcatcctatc aggtttgagt
    31801 aaacttgata ggatgcgttt tagaatgtca aaattttata ctcttcgaaa atctcttcaa
    31861 accgcgtcag ctttcatctg caacctcaaa acagtgtttt gagcaacctg cggctagttt
    31921 cctagtttgc tctttgattt tcattgagta ttaaattgag tttgaagtgg cttatttcaa
    31981 agctttttgt atgtcttcaa tcatgagttt tgttgattca agtccgcctc cgcttagata
    32041 ccagaggtct ggtgttagtt ggataatctt accattttta gcagcaggtg tttcagcgat
    32101 aagggcattt tctaggacac cgtcgttgct agagttgtcc ccaccgatgg caagggtacg
    32161 gttgatgaca aagaggatgt cagggttgat ttctttgaca ctttcaaagc tgacttcttg
    32221 tccgtggcgt gagtcttcaa attttgtatc agttggtttg aatttcaagg tttggtacaa
    32281 gaaagagaaa cgagatttgg caccaaaggc tgccattttt ccttcattaa ggaggatcgc
    32341 aagggctttt ttgtcagagc tttcattttt agtagcgact tcttggatgc tcttgtctag
    32401 cttggccaat tcttccttgg ctttctgtgt accagtttcg ccgaaggcac ttgctaagga
    32461 ttcgatatta gccttggtag aagtccagta gtcgtccttg cttgcttgga agagaacggt
    32521 tggggcgatt tctttgaatt tgtctacgaa tttttgtgta cgtggtgaag cgataatcaa
    32581 atcaggctca agggcggcga tagcttctaa atcaggttct ttcatagaac caacattttt
    32641 gacagttccc actaggtctt ttagataagt cggaacagtt tttgtaggca ttccgacgat
    32701 atttttttca aatcctaaag cgcgaatagt atccgcagcg ccgaggtcaa aggtcacaat
    32761 cttttcagga actttggaaa gtttgacctc ggccagtgaa cttttaatgg ttacctctgt
    32821 tggagcagag ctactggtct ctgtctgact agtgcttgag tttgtactac atgcaccaag
    32881 taggagcaag aagctggcca ctagggcagt gaaataaagt ttaagggatg ttttcataat
    32941 ttctcctctt taaaatgtga taacgattta gggagtctct tgatcttatt gactaagaga
    33001 ctgaaggttc tctaacttga gcttttatgt tactagctat agatacagat ctttttgtca
    33061 ttgatatcag ctagcgtgat gggaatctca taaagttgac tgagcaggtc agcctgcatg
    33121 atttgatcgg ttcttccctt gctaaagacc tggccgtcct tgaaggcgac aatttcatct
    33181 gcatactgac tggctatgtt gatatcgtgg aggacgatga taatggtctt gccgagttcc
    33241 tccaccagtc gtcgaagaat ctgcatcatg ctgacgcttt gcttgatatc gagattgttg
    33301 agtggttcgt ccagcaagat aaagtccgta tcctgggcca gtaccatagc gataaagacg
    33361 cgctggagtt gcccccctga caggctattg atgtagcggt cttttaagtt ggtcagttcc
    33421 aaatagttca gagtttctcg gattttttcc cagtcttctg atctaagtcg acctcggctg
    33481 tagggaaaac gtccaaaact gaccagttct tcaacagtca atttggcttg gtaattgatt
    33541 ttctgtttta ggatggttag ttcttgggcc agttcttgcg aattccagct ctcgatttca
    33601 cgtcctttga tactgagaac tccctgatct ttcttggtta gtctgctcat gatggagagg
    33661 agagtcgatt ttccagcacc atttggacca ataaaggctg tcagtttttg aggactgact
    33721 tcaagcgaaa tgccttgcaa aatatcctgt ttttgaatgg atttgtcaat gttttccagt
    33781 ttcactgacg agccctccta tatagtaaga taaagaataa gaagccaccc acactctcaa
    33841 tgatcatact gatacgaatt tccagtgcaa agactcgttc aatcaaggct tgccccaagg
    33901 ttaagctaat aaatccaacc agaatggcca ctataaagag taacttgtgc tgatagtctt
    33961 tgacaatcag gtaggtgagg ttggccagca taaagccgaa gaaggccata ggtcctacca
    34021 aggcagtggc cgttgaggtc aaaagcacga ttccccagag gagctctttc tgttcttttt
    34081 caacatcgag tcccaatatc tgagccgttt ctctttgcag gtgcaagaca tctagaacga
    34141 ctgcttttcg aaagaaaaag attgtcaaag cgaggatgat cagagaaccg atggctagga
    34201 tggaagtgtt gagatgttga aaggaggcaa aaagactatt ttgcagttta tcgtattcgt
    34261 ttggatccat taggacttga aggaaggtgc tgatatttcg aaagagactt ctgagcgcta
    34321 gacagatcag caggatgaag accaggtctt gcttcatcag tgtcttcaag taaccttgta
    34381 aggcgagaaa gaagagggac tggacaagaa gtaagactag gaattctaag ataggggatt
    34441 tgccaagttg aagaaacttg ctttcaaaaa ccagtagtag ggtttgtagt aggacgtaga
    34501 aggattcaat tcccaaaata ctaggcgtca ggaagcgatt ttccgtcagg gtttgaaaac
    34561 taatggtcga aatcccagtc gcgatggcta ccaagagata aacgatgatc ttttgggaac
    34621 gcaacttcca agcaaaggct gacaagtgag tgatgggcca aaagtagaga agacaagctc
    34681 cgatggcaag aataatgaga atccagaaga gcttggtatg tttgctttta gtctgcatct
    34741 tttcgtcccc ctctccagag aagtaggata aagacgagac taccgatgat tcctagcaag
    34801 agactgacag acaactcata gggcctaatc agaactcggg ataggatatc gcaagccaga
    34861 actagattgg caccaaccag tgcgaccatg agtttggttt gacttagatt atctccatag
    34921 cgcttgcgaa caagattggg aacgataact ccgagaaatg gtaggccacc cacggtaatc
    34981 atggtgacgc ttgtcgttag cgccaccaga aagagggcca gtttttcaag tagggagtag
    35041 gaaatcccca aactctcgct ggtttctttc cctagattca tgatggtgaa ggtttgggat
    35101 aatttccaaa cggttatcag gatgatgagg cctaagaaga gccactcata ctgatgggtc
    35161 tgaatcatgg agaaggagcc ctgggtccag gcagtcatac tctgaaccag attgaaacga
    35221 taggcgataa cttctgtgac tgagccgata atcccgctat agatgatccc aatcagaggc
    35281 aacatccacc tttcctttac agtaaaaatg gtcataaagg ctaggaagaa gagggtgaat
    35341 acgatggatg aaacaaaagc gaagagcatc ttttgggtca gactagccga tggaaagaca
    35401 aaaaggctca gcaccattcc cagtttgggg gcttcagtcg ttccaactgt actcggtgca
    35461 gcaaactgat tttgggtaat agtctgcatg agaaggcctg ccatactcat actagaggca
    35521 gtcaggagaa tactgatagt tcttgggaga cgggactctt gaaagaggag ccaggtctgc
    35581 tggtcgaaat caaatagctt tccccatgaa aaatcactgg tcccaatgct aatagagaga
    35641 aagactagga gtagaagtaa gccaattaaa taatgagaaa gtttcatacc ccgtcctttc
    35701 atgtagattt ggtatcgaaa gatatctgcg gatataaatg taacattatt tttctaatct
    35761 gtcaataaaa tttctgacaa tttaataaat acaacaagga gagagcaaca agactttctc
    35821 ctttgttatc ctattctaaa atgtttttac cttaatctga taaaataata tcttcgaggg
    35881 agtagctagc cgtccaatca agatattgtt tagcttttga agcatctgct aggacactgg
    35941 ctgggtcact agcacgtcga gcaacaatct cgtgtgggat tttttaattt agtaattctt
    36001 cagcagtttt aaagatttct ttgatagtat agcctttttt agttcctaag ttaaagattt
    36061 gagaagaact gtcttcttga aataggtagt tcattccttt aacatgagcc tatgcaaggt
    36121 ccaagacata aatgtaatct cgaatacatg aaccgtcacg tgtatcgtag tcatctccaa
    36181 atatttttaa gctatcattt tgtcccaatg cggtcttgtt gatatttgga atgatgtgag
    36241 ttggattttt cacacgcaga ccgtttgaag catccatttc agccccagca acattaaagt
    36301 aacggaaaat aacatatttc cagtcgtagc gattggccat ccagtaaatc attcgttcgc
    36361 ccatcagttt tgtctctgca taagggttga cagggtcgag cagggtatct tcagtcaccg
    36421 gcttgtcaat acagttattt ccatagagag aagcagtcga agagaacatg attttttgaa
    36481 tgccaacttc agataagact ttgagaactt ggttcatacc agcaacgttg gcagtgaagt
    36541 atttacttgg attttcaata ctttcgctca caacaatttc acctgcacaa tggaggacag
    36601 catcaatctg attttcttct aagtaagcct ttaaggcgct agcatcataa acatccagtt
    36661 ctttaaagct agcacgacta tccacagccg ctcgatttcc tgtggagaga ttatcgagga
    36721 catgcacctt atagccagca tttaaaagag ctttaacggt atgggagcca atgtagctag
    36781 tcccacctgt aacaagaatt gttttggtca tgattttttc cttttctagt tttgtactat
    36841 agtaaattga aataagatat gaacaactct attaggaaag tcaaattaat ttctagaaat
    36901 gtttcagcag ctacagcgta ctattccaaa ctcaaccaac tatatattta aagaaagaag
    36961 aaagggaagt caactatttt ctgtaaattt catgaaaaat ccaaacaact ttgatggtgt
    37021 attgtttttt tgtttggaaa taaatattcg agttaatttt ggaatgttta ctagattttg
    37081 cactacatgc aagagaatac tatccttttc taagatagag caggactaag atactaactt
    37141 agaaatccac cttcccacta tccttctcct ataaaaagtg gtaaaatgga tgaaagaaag
    37201 aaggaactga aatgacaaca ttattttcaa aaattaaaga agtaacagaa cttgctgcag
    37261 tctcaggtca tgaagcgcct gtccgtgctt atcttcgtga aaagttgaca ccgcatgtgg
    37321 atgaagtggt gacagatggc ttgggtggta tttttggtat caaacattca gaagctgtgg
    37381 atgcaccgcg cgtcttggtc gcttctcata tggacgaagt tggttttatg gtcagcgaaa
    37441 tcaagccaga tggtaccttc cgtgtcgtag aaatcggtgg ctggaacccc atggtggtta
    37501 gcagccaacg tttcaaactc ttgactcgtg atggtcatga aattcctgtg atttcaggtt
    37561 ctgttcctcc gcatttgact cgtggaaagg ggggaccaac catgccagcc attgccgata
    37621 tcgtttttga tggtggtttt gcggacaagg ctgaggcaga aagttttggc atccgtcctg
    37681 gtgataccat cgtaccagat agttctgcaa ttttgacagc caatgaaaaa aatatcatct
    37741 caaaagcttg ggataaccgc tacggtgtcc tcatggtaag cgagctagct gaagctttat
    37801 caggtcaaaa actcggcaat gaactctatc tgggttctaa cgtccaagaa gaagttggtc
    37861 tgcgtggcgc tcatacctct acaaccaagt ttgacccaga agtcttcctc gcagttgatt
    37921 gctcaccagc aggtgatgtc tacggtggtc aaggcaagat tggagatgga accttgattc
    37981 gtttctatga tccaggtcac ttgcttctcc cagggatgaa ggatttcctt ttgacaacgg
    38041 ctgaagaagc tggtatcaag taccaatact actgtggtaa aggcggaaca gatgcaggtg
    38101 cagctcatct gaaaaatggt ggtgtcccat caacaactat cggtgtctgc gctcgttata
    38161 tccattctca ccaaaccctc tatgcaatgg atgacttcct agaagcgcaa gctttcttac
    38221 aagccttggt gaagaaattg gatcgttcaa cggttgattt gattaaacat tattaaacca
    38281 taagggaggt ggtagggatg gtagaaccaa acctagaaag ccttataaaa gatctttaca
    38341 atcatgctcg acatgatttg agtgaagatt tagttgctgc tctcctagag actactaaaa
    38401 aactgcctac tacaaatgag caattgcagg cagttcgtct ctcaagcctg gtcaatcgtg
    38461 aattgctcct aaatcccaaa catccagcac ctgagttgct caacttggct cgctttgtca
    38521 aaagagaaga agccaagtac agaggaactg cgacttctgc gcttatgtat gaggaacttt
    38581 ttaaaatgct ttgattccat tgtggatcaa agcatttttt ataagaccta tctcgtgagc
    38641 gttcaaatag tagtaacaag gaatcatgag aagtcagccg agaccatagt agtgaagaaa
    38701 cttctgtaat ggaagtggag tgaagtgagg aatcatcaaa cggtagggga taggctgttt
    38761 gaagggtgct acgaaaaaga tagggtaagg tgaaattata gcggaatgaa ataagatatg
    38821 aacaaattga ttagggaaat caaatgaatt tatagaaatc ttttagcagt catggcgtcc
    38881 tattctagtt tcaaaatgct ataaatacga acaaattgat tgggaaattc aaatcgcttt
    38941 ctatcaatgt tttagaagat acagtgccct agtccaactt caatatacta taaaagaaca
    39001 gatggaagca attatgattt acttctatct ttaaaataaa tgatctgata ggaaaaatgt
    39061 gtcccctcat aaaaaatagg atagtacgga tggaaggctt ttgtagactg gaggacgaag
    39121 gaatttagaa actctcgtta aaagttagtt gagccggagt atggtggtgt gaataattat
    39181 caaaaattat ttccaaatcg aaatagttga cagttagaac gatgagtgtt acaattattt
    39241 tattcatttc gatatcgaaa taaattggag gtgttatgaa agatagtcat ttgctagccc
    39301 atcatattcg tttgttgaat gggcggattt ttcaaaagtt actgagtcaa gatcctgagg
    39361 ctctttatag gggtgaacag ggcaagattt tagcggtttt atggaatagt gaaactggct
    39421 gcgcaactgc gacagatatc gcgcttgcga ctgggcttgc gaataatacg ctgacgacta
    39481 tgataaaaaa gctagaggaa caaaagcttg taattgttag tccgtgtgga aaagacaagc
    39541 gtaagaagta tttagtttta acggagttag gcaagttcca gaaagaagtg gggcatcgtg
    39601 tcagtcagaa attggatact atcttttaca aaggattttc agaggaagaa attcaccaat
    39661 ttgaaggttt tcaagaaaga attttggcaa atctgaaaga gaaggaaaat gaggtttaga
    39721 atatgtcaca acaagtgaaa aatgctcaca acctatacat ccatgccatt caagacggac
    39781 gagttgctga ggctcaagcc cagtctgtag gggataccta tatccaacat tcgacaggtg
    39841 ttcctgacgg gaaagaagga tttgcagcct tctttgcaga tttctttgag cgtcatccag
    39901 agcgtcagat taagattgtc cgcaccattg aggatggcaa tctggtcttt gttcatgttc
    39961 atcaatatct gaatggtgga gaagctcaat gggtgacgac ggatactttc cgtgcggatg
    40021 agaatggtcg tattgttgag cattgggatg tcattgacta ctatcgaaca cctgaaaatg
    40081 accaactaga tcaaattttt ggagattttg aaatcaagga tttggacaag aaagcagaaa
    40141 ataaaaagct ggttcgccgt ttcttgacag aaactttcca aaatggggag ctagagcagt
    40201 ggagtgatta tgtggcagac gatttgattc agcataatca tgagattgga caaggaagtg
    40261 ctgcttataa aaactatgtg gctgaatata gtgtcacttt tgactttgtt ttccaactct
    40321 taggacaagg aaactatgtg gttagctatg gtcagactca gattgatggc gttgcttatg
    40381 cccagtacga tatcttccgt ttagagaacg ggaaaattgt ggagcattgg gataataagg
    40441 aagtcatacc taaggtagaa gacttgacta atcgagggaa gttttaaatt gaggacaaag
    40501 aatgattgaa tacaaaaatg tagcactgcg ctacacagaa aaagatgtct tgagagatgt
    40561 caatttacag attgagaatg gggagttcat ggttttagtt gggccttctg ggtcaggtaa
    40621 gacgaccatg attaagatga ttaaccgtct cttggaacca actgatggaa atatttatat
    40681 ggatggcaag cgcatcaaag actatgatga gcgtgaactt cgtcttacta ctggatatgt
    40741 tttacaggct attgctctct ttcccaatct aacagttgag gaaaatattg ctctcattcc
    40801 tgaaatgaag ggttggacta aggaagaaat tgctcaaaaa acagaagagc ttttggcaaa
    40861 agttggatta ccagtagctg agtatgggca tcgacttcca agtgagctat ctggtggaga
    40921 acagcaacgg gtcggtattg tccgagctat gattggtcag cccaagattt tcctcatgga
    40981 tgaacccttt tcggccttgg atgctatttc gagaaaacag ttgcaggttc tgacaaaaga
    41041 attgcataaa gagtttggga tgacaacgat ttttgtaacc catgatacgg atgaagcctt
    41101 gaagttggcg gaccgtattg ctgtcttgca ggatggagaa attcgccagg tagcgaatcc
    41161 cgagacaatt ttaaaagtgc ctgcaacaga ctttgtagca gacttgtttg gaggtagtgt
    41221 tcatgactaa tttaattgca acttttcagg atcgttttag tgattggttg acagccctat
    41281 ctcaacattt gcagttgtca cttttgacct tgttactagc tattttgctt gcgattccct
    41341 tggctgttta tcttcgctat catgagaagt tggcggattg ggtcttacag attgcaggga
    41401 ttttccagac catcccgtct ctggccttgt tgggactctt tattcccttg atgggaattg
    41461 ggactttacc ggcattgaca gctctagtga tttatgcgat ttttccgatt ttacaaaata
    41521 ctattactgg gctgaaggga attgatccga gtcttcaaga ggctgggatt gcctttggga
    41581 tgaccagatg ggagcgtctc aagaagtttg aaattccact tgccatgcct gttatcatgt
    41641 ctggaattcg gacggcagcg gtcttgatta tcggtacggc taccttggcg accttgattg
    41701 gggcaggggg actgggttcc tttatcctgt tgggaattga ccgtaataat gccagtttga
    41761 ttttgattgg ggccctttct tctgcagtgc tagctattgc ctttaacttc ctactaaaag
    41821 taatggaaaa agcgaaattg cggacgattt tctctggttt tgccttggtg gctttattac
    41881 tgggtctgtc ttatagtcca gcccttttgg ctcaaaaaga gaaggaaaac ttgattattg
    41941 ctgggaaaat aggcccagaa ccagaaattt tggctaatat gtataaattg ctgattgaag
    42001 aaaataccag catgactgcg actgttaaac cgaattttgg gacgacaagt ttcctttatg
    42061 aagctctgaa aaaaggtgat attgacattt atcctgaatt taccggtacg gtgactgaaa
    42121 gtttgcttca accatcaccc aaggtgagtc atgagccaga gcaggtttat caagtggcgc
    42181 gtgatggcat tgccaagcag gatcatctag cctatctcaa acctatgtct tatcaaaata
    42241 cctatgctgt agctgttccg aaaaagattg ctcaagaata tggcttgaag accatttcgg
    42301 atttgaaaaa agtggaaggg cagctgaagg caggctttac gcttgagttt aacgaccgtg
    42361 aagatggaaa taagggcttg caatcaatgt atggtctcaa tctcaatgtg gcgactatgc
    42421 agccagctct tcgttatcag gcaattcagt caggggatat tcaaatcacg gatgcctatt
    42481 cgactgatgc ggaattggag cgttatgatt tacaggtctt ggaagatgac aagcaactct
    42541 tcccacctta tcaaggggct ccactcatga aagaagctct tctcaagaaa cacccagagt
    42601 tggaaagagt tcttaataca ttggctggta agattacaga aagccagatg agccagctca
    42661 actaccaagt cggtgttgaa ggcaagtcag caaagcaagt agccaaggag tttctccaag
    42721 aacaaggttt gttgaagaaa tgatgggaca gagactttaa acatactgaa ctcaacttcc
    42781 ttaaacgact agataaaaga atgctcagac aatttcgtct gggctttttt gatgtgagaa
    42841 tgactgaatg tcacttaaaa tggaaagaaa gagaaaattt tcatgatttt ctaaaatttt
    42901 actgtaaaga cagttgacta ttcataaaat aggtgtataa tattttgtga actacttaac
    42961 aaataagagg tttcagctca tgtcgactaa ggttagaaat cttgtgtata ggcagttcat
    43021 tatctaatag agcgttgcgt ccgaaagtct atccagacac ggctctttaa aaacaaaagg
    43081 agaaatgatg catacttatt tgcaaaagaa aattgaaaat atcaaaacaa ccctaggtga
    43141 aatgtcaggt ggttaccgtc gtatggttgc ggctatggct gatttaggat tttcaggaac
    43201 tatgaaggct atctgggatg acctctttgc ccatcgtagt tttgcccagt ggatttattt
    43261 gctggtttta ggaagttttc ctctctggct ggagttggtt tacgaacatc gtattgttga
    43321 ctggattggg atgatttgta gcttgacagg gattatctgt gtaatctttg tatcggaagg
    43381 tcgagcaagt aattatcttt ttggcttgat taactctgtt atttacctta ttttggccct
    43441 acagaaaggc ttttatggtg aggtgctgac gacactttac ttcacagtca tgcagccaat
    43501 tggacttcta gtttggattt atcaggcaca gtttaagaag gaaaagcagg agtttgtcgc
    43561 gcgtaaactg gacggcaagg gctggacaaa gtatctttcc attagtgtgc tttggtggtt
    43621 ggcctttggc ttcatttatc agtctattgg tgccaatcgt ccctatcgtg attcaatcac
    43681 agatgcaacc aatggggtag ggcaaatcct catgacagct gtttaccgtg aacagtggat
    43741 attctgggcg gctaccaatg tcttttcaat ctatctctgg tggggagaaa gcctgcaaat
    43801 tcaagggaaa tatctaattt atctcattaa cagtctagtt ggttggtatc aatggagcaa
    43861 ggcagctaag cagaatactg atttacttaa ctaggaaaag atgtttgaaa gtgctgtttt
    43921 gagatttcga ttaaaacaga tatagttgat aatcaaggat ttatagtatg aaaaagagga
    43981 tcggcgggtc ctcttttgtt gttgaaaaga taaaaaactc agtaacctag aaataagaca
    44041 actgaagttt tactctatat tcaattttta ggaatgagaa ggtctagata aaattggaca
    44101 acttcctggt ctgtgaaatc ttgacctttt ttgagccacc aggtcaatgt ttcgataaag
    44161 ttagttacga caaaatgttg gaggtaagaa gtaggcatat tagggtgggc ttcttttaaa
    44221 ttatcagcta gcacggaata gacatggtgt tctagctctt tatggagttg acggaggaag
    44281 tagtcatttt tggaaaatag cagactggtg atatggtctt ggtttttatg aaaatggaga
    44341 aagaggtggg cgaggtagtc ctcggttgaa atggcttgct ctctttcaaa aagatgatgg
    44401 aagaggtagc ggcagagctg gtccagaaga agctccttac tttcatagtg acagtaaaag
    44461 gtggatcttc ccacatctgc gagatcaatg atatcctgaa cagtagtggc ctcgtagccc
    44521 ttagcattca aaagttgtat aaaagcttga tagatggctt ttttggtttt gctgatacgg
    44581 cggtcaatgt tagtcatatg gacacttaag gcaaattgtt cagaactgaa taaagctgac
    44641 gttttgcttc tatcctttct ttgagtttta gtggataatg ataatgaaca aggtgttcat
    44701 aaatctatta taacaaagga atgagaaata tgaaggcaaa atatgctgtt tgggtggctt
    44761 ttttcttaaa tttgacttat gccattgttg agtttattgc aggtggagta tttggttcta
    44821 gcgctgttct tgctgactct gtgcatgact tgggagatgc gattgcaatt ggaatatcag
    44881 cttttctaga aacaatctcc aatcgtgaag aagacaatca gtacaccttg ggctataagc
    44941 ggtttagcct gctaggagcc ttggtaacag ctgtgattct cgtaacgggc tctgttctag
    45001 tcattttgga aaatgtcacg aagattttgc atccgcaacc agtcaatgat gaggggattc
    45061 tctggttagg aattattgcg attactatca atctgttagc gagtctggtg gttggtaagg
    45121 gaaagacaaa gaatgagtct attctgagtt tgcattttct ggaagatacg ctagggtggg
    45181 tagctgttat cctgatggcg attgttcttc gatttacgga ctggtatatc ctagatcctc
    45241 ttttgtccct tgtcatttct ttctttattc tttcaaaagc ccttccacgt ttttggtcta
    45301 cactcaagat tttcttggat gctgtgccag aaggtcttga tatcaagcaa gtaaagagtg
    45361 gcctggagcg attggacaat gtggccagcc ttaatcagct taatctctgg actatggatg
    45421 ctttggaaaa aaatgccatt gtccatgttt gtctaaaaga aatggaacat atggaaactt
    45481 gtaaagagtc tattcgaatt ttcctaaaag attgtggttt tcaaaatatt accattgaaa
    45541 ttgatgctga cctagaaact caccaaaccc ataagcgaaa ggtgtgtgac ttggaacgga
    45601 gttatgagca tcaacattag aaaaaagtga aaaatacttg ggtactatct tatttggaat
    45661 agagtaattt ctttattatt taaatatttc aaaaattggt aagagaagag cattgtataa
    45721 actccggata tatgattgtt aatgataaaa atttttcgat tagatacaaa atgcttgact
    45781 tggagtcaac tcaaagttat ataataagat aagtgagtta gaatagcgtg aattcagtga
    45841 atgaaatgag aggaggttag cgtgtgaata ttaaatctgc cagtgatttg ttgggaattt
    45901 cagcggatac gattcggtat tatgaacggg ttggtcttgt gccaccgatt actcgtactg
    45961 ctactgggat tcgtgatttt caagatcagg atatcgaagc gctggaattt attaagtgtt
    46021 ttcgttcggc gggtgtctct gtagatagtt tagttgacta tatgtcgctc taccaaaagg
    46081 gagatgaaac gagagaggag aggcttggta ttttagaaga ggaaaagcaa aaattagagg
    46141 agcgcttgtc tcagctacag acagctttaa atcgtttaaa tctcaaaatt aaactttata
    46201 aggaaggaaa attttaaatg aaatcagcag tatatacaaa ggcaggtcag gttggacttg
    46261 ctagcattga acgtccgcaa ataatagaag cggatgatgt gattattcgt gtggttcgtg
    46321 cgtgcgtttg tggttcagat ttatggaggt accgtaatcc agaaacgaaa gctggacata
    46381 aaaatagtgg acacgaagcg attgggattg ttgaagaagc tggggaagcc attacgacgg
    46441 tgaaaccagg tgattttgtg attgtccctt ttacacatgg atgtggtgag tgtgatgcct
    46501 gtcttgctgg atttgacggt tcttgcgaca atcatattgg caataatttg gggggtgatt
    46561 ttcaggcaga atatattcgc ttccactatg caaactgggc gctggttaaa atccctggtc
    46621 aaccttctga ttatacagaa gggatgctca agtccctttt gactcttgca gatgtcatgc
    46681 cgacaggcta tcatgcagcg cgtgttgcaa atgttcaaaa aggggacaag gttgttgtta
    46741 tcggtgatgg ggctgttggt caatgtgctg tcatcgcggc taagatgcgt ggagcatcac
    46801 aaattatcct tatgagccgt catgaagacc gtcaaaagat ggctatggag tcaggtgcga
    46861 cagctgttgt tgcagaacgt ggtcaagaag gaattaccaa ggtgcgtgaa atcctcggtg
    46921 gaggagcaga tgcagcactt gaatgtgttg gtacggaggc tgctatagaa caggcgctag
    46981 gtgttcttca taatggaggg cgtatgggct ttgtaggagt cccacactat aataatcgtg
    47041 ctcttggttc gacatttatg caaaatatct ctgtagcagg tggggcagct tctgctacaa
    47101 catacgataa gcaattttta ctaaaagccg tccttgatgg tgatatcaat ccaggtcgcg
    47161 tctttacttc aagttataaa ctggaagata tcgaccaagc ctacaaagat atggatgaac
    47221 gtaagaccat taagtctatg attataatcg aataaaaaac gaataggagt tctaaaactc
    47281 ctattcgttt tttatgttat cctattcttg atttagggta ctttctctta atgtcagtct
    47341 ggttcccagc atggtcaggc tagggatttt ccgaccgtgg aggacttcct tgttaagaat
    47401 atccatacct gctcggccca tttcttcagt ataaactgta atactagaga ggggaggata
    47461 gacctgtttg gtcagactag tgtcgttaaa ggaaatgagg ctgacgcgat ctggcaggtt
    47521 gattccagct tcttggaggg cacggagggc accgatagct aaactatcgc tggctgcgaa
    47581 aaatgctggc ggaagttggt ctcccaagct ctgaatggcc tccttcatca agtcatagcc
    47641 agactgggca gtaaagtttc cttgaaagat cagttcatca tgatagattc cttttgcttg
    47701 actgtagttt ctgaaatttt ccagccgctt atcctcaatg atttcttctt ggtctgttgt
    47761 ttcttcaagg cctgttagaa tcccgatacg gtccattcct tgactgagga aataatcgac
    47821 aacctgtttc atagcagtgt aaaaatccgt gataatacag gtatgtccca gggaaagtgt
    47881 atcgctgtct agaaatacaa gaggcttttg gtattcttca aaggcagaaa tctgagctcg
    47941 actaaacttt ccgatgcaga gaatcccaat cacttcctcg cttagggtaa aagggtggtc
    48001 attaaaatag cgcaagatat cgtagtccaa ctcttgggct cttttttcta ttcctaggcg
    48061 aatctggtag tagtagaggt cgtctagctc cccttgttcg ctgacccatt gaataatggc
    48121 aatcttttgc ttgggtttgt gggactcgcc tgtcttgagg tgcttggtgt agcccagctc
    48181 ttcagcaacg gttaaaatac ggtgtctggt ttcttctgta acagataggc tctggtcgcg
    48241 gttgaggaca cgggatacgg tcgcgattga gacagaggct agctgtgcaa tgtcttttaa
    48301 ggtagccata aatcctcctt gattaggtta gtatatcata tttttcttct ttttactgat
    48361 attttagtaa aattttagta aaaaggattg accttgggaa attccttgga tacaatagaa
    48421 agaaaacgat tacacgttaa gatggcttaa cggacagtca aaggagaatt catatggcac
    48481 aacatcttac tactgaagtc cttcgcaaag actttcttgc tgtttttggt caagaagcag
    48541 accaaacctt cttttcacca ggccgtatta atttgattgg tgaacacaca gactacaacg
    48601 gtgggcacgt ttttcctgct gctatttcct tgggaactta cggtgcagct cgtaagcgtg
    48661 acgaccaagt cttgcgtttc tactcagcta actttgagga caagggcatt atcgaagtgc
    48721 ctctcgctga cctcaagttt gaaaaagagc acaactggac caattatcca aaaggggttc
    48781 ttcatttctt gcaagaagct gggcacgtga ttgacaaagg ttttgatttt tatgtttatg
    48841 ggaatatccc aaatggtgct ggcttgtctt cttcagcatc cttggagctc ttgacaggag
    48901 tcgtggcaga gcatctcttt gatttaaaac tagaccgttt ggatttggtt aaaatcggaa
    48961 aacaaacaga aaacaacttt atcggagtca actctggtat catggaccag tttgctattg
    49021 gtatgggggc tgaccaacgt gctatttact tagataccaa tactttagaa tacgacttgg
    49081 tgccacttga tttgaaggac aatgtcgttg ttatcatgaa caccaacaaa cgccgtgaat
    49141 tggcggactc taaatacaat gaacgtcgtg ctgagtgtga aaaagcagtg gaagaattgc
    49201 aagttgcctt ggatattcag accctgggtg aattggacga gtgggccgtt gaccaatata
    49261 gctatttgat taaagatgaa aatcgtttga aacgtgctcg ccatgctgtg cttgaaaacc
    49321 aacgtaccct taaagctcaa gcagcccttc aagcaggtga tttggaaaca tttggtcgtt
    49381 tgatgaatgc gtcacacgtt tctctggagc atgattatga agtaactggt ttggaattgg
    49441 atactcttgt tcacacagct tgggcacaag aaggagttct cggtgctcgt atgacagggg
    49501 ctggttttgg tggctgtgcc attgccttgg ttcaaaaaga tactgttgag gcctttaagg
    49561 aagctgtagg caaacactac gaggaagtag ttggatacgc tccaagcttc tatatcgctg
    49621 aagttgcagg tggcactcgc gtccttgact agtcaaaagg aggctctata gtgatcttag
    49681 tagataaatt tgtaacacat gtcatttctg aaagttcatt tgaggaaatg gatcgaatct
    49741 acctgaccaa ccgtgttttg gcacgagtgg gagaaggtgt tttggaagtt gagaccaatc
    49801 tggataaatt gattgacctc aaggaccagc tagttgagga agccgttcga ttagagatga
    49861 ttgaggatag tcagactgcg cgtgaaatcc ttggtactga actgatggac ttggtgactc
    49921 cttatccgag tcaggtcaat cgtgacttct gggaagccta tgtccactct cctgagcaag
    49981 cgatagagga tttttatcaa ctcagtcaga aaaatgatta catcaaactc aaggccattg
    50041 ctaaaaatat cgcttatcgt gttccatctg attatggaga acttgaaatt accatcaatc
    50101 tctctaagcc tgaaaaggat ccgaaagaga ttgcggtagc caagttggtg caagctagta
    50161 attatcctca gtgtcaactt tgtttagaga atgagggtta ccatggtcgg gtcaaccacc
    50221 cagctcgcag caaccaccgg attatccgtt ttgaaatggt tggtcaggaa tgggggttcc
    50281 agtattcgcc ctatgcttac tttaatgagc attgtatctt tttagatggc cagcatcgtc
    50341 ccatggccat tagtcgtcag agttttgaac gtctgttggc tatcgtagag cagtttccag
    50401 gatattttgc tggatctaat gccgacctgc cgattgtggg gggctctatt ctaactcatg
    50461 atcattatca gggaggccgt cacgtatttc ctatggaatt ggctcccttg caaaagacct
    50521 tccgatttgc tggttttgag caggtcaagg ctggaattat caagtggcca atgtctgtcc
    50581 tacgcttgac ttcggattcc aaagaggatt tgattaactt agctgataag attttccagg
    50641 aatggcgtca gtattcagat tctagtgtgc agattttagc agagacagac gggacaccgc
    50701 atcacaccat cacaccaata gcgcgtaagc gtgatggaca gtttgagttg gacttggtct
    50761 tgcgagacaa tcagacttca gcagagcatc ctgatggcat ctatcatccc cacaaggatg
    50821 tccaacatat caagaaggaa aatatcggct tgattgaggt catgggcttg gcaatcttgc
    50881 caccacgtct gaaagaagaa gtagagcaag tcgctagcta tcttgtagga gaagctgtta
    50941 cagttgccga ttatcatcag gagtgggcag accaactcaa atcccaacat ccagacctaa
    51001 cggataaaga aaaagccctt gcaatcgtca aggactctgt gggtgctatc tttgtgcgtg
    51061 tacttgagga tgcaggagtc tacaagcaga cagaacaagg gcagacagcc tttatgcgct
    51121 ttgtggaaca ggtcggaatt ttactagact aggagctttc tccttgcaca gtcctataaa
    51181 aagtagtatc atagtgtcgt ttgaaatatc aggaggaaac gatgaaagac tttcattttg
    51241 acgctatatc tgcctttgaa agttacgaaa ttgaaaaaat gagagatggt cacgttgtgg
    51301 tgacgaccaa agtagtgaac tcatcgctca actactatgg caatgcccat ggtggctatc
    51361 tattcacgct atgtgaccaa atcagtggtt tggtggttat ctcgctggga cttgatgggg
    51421 tgacactcca atcctctatc aactacctta aggcaggaaa actcgacgat gtattgacca
    51481 ttaaaggaga atgtgtccat caaggtcgta caacctgtgt gatggatgtg gatatcacca
    51541 atcaagaggg cagaaatgtc tgtaaggcaa cctttaccat gtttgtcaca ggccaaaggt
    51601 ctgaggaaag acgggtaagt atataaagaa aggtgagtgg gataaattta tctcactcat
    51661 ttttaattta tgagatatgt tagaaggaaa tataaaagag agtgatgaaa tacaaatgta
    51721 ataggtacat atatgtggta tactagttat agtagatttt aattgcttat atcgagtgag
    51781 ttctcatatt agtgaggaat ttttaaatgg aattacactt taatttagaa ttagtagaaa
    51841 cctataaaag taatagccaa aaggcacgta tcttaacgga ggattgggtt tatcgtcagt
    51901 cttattgccc taattgtggg aacaatccct taaatcattt tgaaaataat cggcctgtag
    51961 cagattttta ctgtaatcat tgtagtgagg agtttgaact aaagagcaaa aaaggaaatt
    52021 tttcatcaac aatcaatgat ggtgcttatg caacgatgat gaagcgtgtg caggcagata
    52081 ataatcctaa tttctttttt ttaacttaca caaaaaattt tgaggtaaat aactttcttg
    52141 tccttccgaa gcaatttgtt acaccgaaat cgattattca aagaaaacca cttgcaccaa
    52201 ctgctagacg agcaggttgg attggttgta acattgattt atcacaagta ccttctaaag
    52261 gaaggatatt tcttgtgcaa gatggacaag ttagagatcc agaaaaagtt acaaaagaat
    52321 ttaagcaagg tttattttta aggaagagct ctctgtcatc aagaggttgg acaatagaaa
    52381 ttctaaattg tatagataag atagagggtt cagaatttac ccttgaagat atgtatcgtt
    52441 ttgaaagtga cctaaaaaat atctttgtta agaacaatca tatcaaagaa aagattaggc
    52501 aacagcttca aatattaaga gacaaagaaa taatagaatt taaaggtaga ggaaagtatc
    52561 ggaaattatg aaaacgaaac aacttgttgc atcagaagag gtgtatgatt tcttaaaagt
    52621 catctggcct gattatgaaa ctgaaagccg ttacgataac ctaagtttaa tcgtctgtac
    52681 cttatcagat cccgattgtg tgagatggtt atctgaaaat atgaaatttg gtgacgaaaa
    52741 acaactagct ttgatgaagg aaaaatatgg gtgggaagta ggagataaat tgccagagtg
    52801 gctacatagc tcctatcata gattattgtt aataggtgaa ttattggaaa gcaatctaaa
    52861 actgaaaaag tatacagtag aaattacaga aactttatca cgtttagtaa gtatagaggc
    52921 tgaaaatcca gatgaagccg aacgacttgt aagagaaaag tataagagtt gtgaaattgt
    52981 tcttgatgca gatgattttc aggactatga cactagcata tatgaatagg tagatgtttt
    53041 tattttgtca cacaaaaaag aggctcgcac ctctttttct tatttctttt tatgatttaa
    53101 tacggcattg aggacaatag cgagtaggct ggctacgacg attccgtttg agaagaacat
    53161 ttggaaggct gtcggcatgc tgacaaagag attactgttg ttgagaccga cacctgcagc
    53221 gattgaaaca gctgcgataa ggaagttgtg ttcattgtta gcaaagtcaa ctcgggcgag
    53281 gatttgcatc ccttgaatag atacaaaacc aaacatcacc agcatggcac cgccgaggac
    53341 ggagcttgga atgatttggg caagggcacc aaacttagga agcagtccaa ggagaaccag
    53401 gaaaccagct gcgtagtaga ttggcaggcg ttttttgatg cctgacaatt taaccaaacc
    53461 aacgttttgt gaaaatccgg tgtaagggaa ggtgttaaag attcctccga gaagtaccgc
    53521 caaaccttct gcgcggtaac cgttgcgaag gcgcgtgctg tcgattggat cttttgtgat
    53581 atcagacaag gctagataaa caccagttga ctcaaccata gacaccgttg cgatgataca
    53641 catcatgaca atagatgaga tttcaaaggt tggcatccca aagtagagtg gagttgggac
    53701 atggacaagt ggagctaccg caacaggaga gaagtccacc aagcccatag tagcagcaat
    53761 ggcagttcca acaaccagac caatcaaaat agagatagac ttgataaatc ctttggtaaa
    53821 gatgttgatc aagaggataa tcagaacagt aatagctgca agcaagagac tttgaccagt
    53881 tggctctgga acgttatttc ccatatttcc aatagcgaca gggatcaagg ttaaaccaat
    53941 cgtggtaata acagatcctg ttacgataga tgggaagaga ttggctactt ttgagaagat
    54001 gcctgaaaca agaaccacgt aaatcccaga tgcgataagg gcaccaaaca tagcgccatt
    54061 accatggctt tgcccaatca taatcaaggg agcgaccgac tggaatgcaa ctccaagaac
    54121 gactgggagt ccaatcccaa agtatttgtt gagttggagt tggaggaagg ttgccacccc
    54181 acacatgaag atatctgtag aaatcaggta ggtcaactgc tcagctgaat agccaagggc
    54241 tgtcgcaatc atgatgggaa ccaggataga tcctgagtac atggctagta agtgctgcaa
    54301 gcccagaacg gctgcttgcg agtgtttttc ttgagtttgc attagagatc tgcctcctta
    54361 aatacgacct gaccattttc aaaacgatcc aagcgagcaa gtgataggac agggtagcct
    54421 gctttttcaa gcaaatcacg accatcttgg aaggatttct caatcacgat accgatagct
    54481 tggactgtgg caccggcctg ttcgatgatt tgaatcaagc ctttagcagc ttggccatta
    54541 gcaaggaaat cgtcgataat caaaaccttg tcctctggtg agaggaattt tccagcgata
    54601 gaaacagtgc tggtcacctg cttggtaaag gagtagactt gagcagttaa gatgccttcg
    54661 ttcatggtga tgttcttagc ttttttggcg aaaatcatgg gaacgtttaa ggcttcagct
    54721 gtaaaaacgg ctggggcaat acccgacgct tcaatggtta cgaccttggt aatgccagta
    54781 gcagcaaatt tttccgcaaa aaccttacca atctctcgca tcaagctaaa gtcaacttgg
    54841 tgggttaaaa aggaatctac cttgaggatg ttatcaccca agatatgccc atccttgagg
    54901 atgcgctctt ctaataattt cataagacct cctaaagtct aaaagttaat ttacttgttg
    54961 tttaaatatt tctatagtga tcccttttgc taatactata tatttgataa aactattacg
    55021 agcgaagcga gtcttatcaa atatttcccg ttgtagtggt atcatagaca ataatcttgt
    55081 tattgtctat gacgggattt ttgagagtaa aatagttcgg ggaactattt tagcctaagc
    55141 ctagaaatga aagagctagg ggctcaaaaa ttagggatga aattccctgg attcctgaaa
    55201 ttattcacag gataatttca cctcccgtcc gcactaatta agggaaatat taaaaatatt
    55261 caaaaaagac ctacttaatc tctaagtaag tcccctaaat agacatggca aaaacggcca
    55321 tatctcactg ctgacttact tattgttagg tgttccggca ccttgtagaa acgtcgtgcc
    55381 aattcacgac ataaacaagt aaaacgatat tcaattttaa ataggcttga gccaatgttt
    55441 ttattttaca ctaaataact ttagaaatca actattttgt tagtgttttg gtttaaaaag
    55501 cgaacaaaaa taagagaggg tgaacaaaaa ctccattgta agctaacatt tatactaaat
    55561 gaaaatcaaa gagcaaacta ggaagctatc cacaacctca aaacactgtt ttgaggttgt
    55621 ggatagaatt gacagagtca gtatcatata cctacggtaa ggcgacgttg acgtggcttg
    55681 aagagatttt cgaagagtat tagaagattt ttccatcata aaaggcatac tatcaagttt
    55741 ttagacacct gacaatatgc ctttttctaa ctttaaagac ttttcccaat ttttattatt
    55801 ctactcgcta aatcttaaaa aatagccatc tggatccaaa actgcaaatt tatgaggata
    55861 gatataggga tcactgacac gaaactttct tttggtcaag agacgataaa taggatagtt
    55921 tgcctccatc actttttgat agagttttgg aacatccttt atgccaaagg agagattgac
    55981 tccacgacca aaggggtagg tcagttcagc tagttgatcc tttgttccct cctctaacat
    56041 tagttgacac tcttcaagag aaagagaaag ttttcttctg gacgttagta ttcaatccta
    56101 aaacccagta aaccacagta gaaggaccgg gactgttcga tattcgatac aagaaactcg
    56161 ggaatgaccg cattgtagtc catatagaaa atccttacaa gtcaatttcc aagacaatcg
    56221 gtgtatggtc ttggcgagca cctgagtcaa tcatatcaga tttagtgacc ttgtcagcga
    56281 tacggttact tgtgagccag tagtcgattc tccagcctgt attgttgatt ttagaagttt
    56341 tgctgcgttg tgcccaccaa gtgtagcgtt caggaacatc gccatgaaca tggcggaagg
    56401 tgtctgtaaa tccagttgcc aaaaggttgg taaatccagc acgttcctcg tcagtaaatc
    56461 caggtgaacg gcggttgcta gcaggatttg caaggtcgat ttcattgtgg gctacgttgt
    56521 agtcaccggt cgcaaggact ggtttttctt tgtctagttc agccaaatac tcagcatatt
    56581 taacatccca gacttggcgt tcttccaagc gtttgagacc gtcaccagcg tttggagtgt
    56641 aaacttgggt tacgaaaaat gcatcaaatt ctagagtgat gatacggcct tccaagtcca
    56701 tggtagaagg ggcaccgatt tctggaaaac tgatcgtagg cgtaagttct ttcttataaa
    56761 ggaacatggt tccagcatag cctttacggg caggctcttg ggaagagcgc catgtgtttt
    56821 cgtagcctgg gaagagttct tctaaaattt ccacgtgttt ctttgtaggt cctttggcag
    56881 aaagcttggt ttcttggata gcaatgatat cagcattttc agcgaccaag gtttgtagga
    56941 cttcttggga caatttggca cgagctgagt cactagttag ggcagcgttt agggaatcaa
    57001 tattccatga gataagtttc ataaagttac ctttttcatt cagattatag attttattat
    57061 accaaaaaaa gatctatttc cccaacgtat ggtttgaaaa attactctct ttcgtttata
    57121 attaagaatg attttatgaa agggagtgaa aatatatgaa attctactct tatgactatg
    57181 tactcagcca aatcggtcag caaaatggta tcatggttgg ctttgggatt gttctattag
    57241 ctgtgacagt tttttttgct ttcaaggcat accatgataa aaagggaacc gaatttcgtg
    57301 agttggtcat gatttcagct ctggccttat ttagctctgc ttttggtcag catcacgact
    57361 tatcaaaaca atcaagtttc taacaataaa tttcaaactt cacttcattt catcgaggtt
    57421 gtttccaaag atttgggagt agacaagtca gaagtctatg ttaatacttc cacaaacaca
    57481 gatggcgcac ttatcaaggt gggagatcgc tattatcgtg ccctaaacgg aagtgagcca
    57541 gacaagtacc tgttagagaa agtcgaattg tataagacag acgcaattga actggtggat
    57601 gtgaacaaat gacacttaat tatatcgaaa ttttaatcaa actggtcttg actctcaaat
    57661 ggctcaacaa caatgttcac tttgtgaaac gtttgattga tggtaagcca actctcctta
    57721 tcaaaaatgg gaatattgac ccagaagcct gtcgttcagt tggtttgtct gcatcggatg
    57781 tagccctcaa acttcgtagc caagggattt tccagatgaa gcaagtcaaa cgagctgtgc
    57841 aagagcaaaa tgggcaactt atcgttgtgc aaatgggaga tgaaaatcct aagtatccag
    57901 ttgtgactga cggtgtgatt caagtagatg tcttggaatc gattggtcgt agcgaagagt
    57961 ggttgcttga taacctcagt aaacaagggc atgacaatgt agccaatatc tttattgctg
    58021 aatatgacaa gggtgctgtt acagtcgtaa cttatgaaaa agaaaaacct ggggtcttgt
    58081 actcttcgaa aatctcttca aaccgcgtca acgtcgcctt gccgtatgta ggttactgac
    58141 ttcgtcagtt ctatctacaa cctcaaagca gtgctttgag cagcctgcgg ctagtttcct
    58201 agtttgctct ttgattttca ttgagtattg gcctcaggtt tccatttgca atcagaaagg
    58261 gattttatgt ccattattca aaaactttgg tggtttttca agttagaaaa acgccgttat
    58321 ctagtcggaa ttgtggccct ggtcttggtt tccgtcctca atctcattcc tcctatggtt
    58381 atggggcggg ttattgatgc catcacatcg gggcaattaa cccagcagga cctccttctt
    58441 agcctatttt acttgctact tgcagccttt ggtatgtact atttgcgcta tgtgtggcgt
    58501 atgtatatcc ttgggacctc ttattgcttg ggacagatca tgcggtctcg cttgtttaag
    58561 catttcacaa aaatgtcgtc agccttttat caaacctatc ggacgggtga tctgatggca
    58621 cacgcaacca atgatatcaa tgccttgact cgtttagcag gtggcggtgt catgtctgcg
    58681 gtggatgcct ctatcacggc tctggtgact ttgttgacca tgctctttag catctcatgg
    58741 cagatgactc ttgttgccat tctcccccta cctttcatgg cctatgcgac tagtcgccta
    58801 gggagaaaga ctcataaggc ctttggcgaa tcccaagctg ctttttctga actcaataac
    58861 aaggtacagg agtccgtatc aggtatcaaa gtgaccaagt ctttcggtta tcaggcagac
    58921 gagttgaagt cttttcaggc agtcaatgaa ttaaccttcc aaaagaacct gcaaaccatg
    58981 aaatatgata gtctctttga ccctatggtt ctcttgtttg ttggttcgtc ctatgtttta
    59041 acgcttttgg ttggctcctt ggtggttcag gaagggcaga ttacagttgg gaatctagtc
    59101 acctttatca gctatttgga tatgctggtc tggcctctta tggccatcgg cttcctcttt
    59161 aatactactc agcgagggaa ggtttcttac cagcggattg aaaatctttt gtctcaggaa
    59221 tctcctgtac aagacccgga gtttcctctg gatggtattg aaaatgggcg tttggagtat
    59281 gccattgaca gctttgcttt tgaaaatgag gaaacactga cggatattca ctttagtttg
    59341 gcaaaagggc aaacactggg cttggttggg cagacaggct ctgggaaaac gtccttaatc
    59401 aagctcctct tgcgtgaata cgatgtggat aagggcgcca tttatctaaa cggtcacgat
    59461 attcgggact atcgtctgac agaccttcgc agtctcatgg gctatgttcc tcaggaccag
    59521 tttctttttg cgacttcaat cctagacaat atccgctttg gcaatcctaa cttgcccctt
    59581 tcagcggtcg aggaagctac taagctagcc cgagtttacc aagatattgt agacatgcct
    59641 caaggatttg atacgctgat tggtgaaaaa ggagtcagtc tttctggtgg tcaaaagcaa
    59701 cggttggcta tgagtcggac tatgatttta gaccctgata tcttgatttt ggatgattcc
    59761 ttatccgccg tagatgccaa gacagagtat gcgattatcg acaacctcaa ggagacgcga
    59821 aaggacaaga caaccattat cactgcccat cgcctgagtg cagttgtcca tgcagatttg
    59881 attttagtcc tgcaaaatgg tcaaattatc gaacgaggca ggcacgaaga cttgctagct
    59941 ttggatggct ggtatgccca aacctaccag tctcagcagc tggaaatgaa gggagaagaa
    60001 gatgcagaat aaacaagaac aatggactgt attgaagcgc ttgatgtcct atctcaagcc
    60061 ttatggactc cttacctttt tggcactcag ttttctccta gcgacgacgg tcattaaaag
    60121 tgtcattccc cttgtggctt cccactttat cgaccagtat ctcagcaatc ttaaccaact
    60181 agccgtgacc gttttgctgg tctactatgg tctctacatc ctacaaactg tagttcagta
    60241 tgtcggcaat cttctctttg cgcgcgtgtc ttacagtatt gttagggata ttcgtcggga
    60301 tgcctttgcc aatatggaga aactgggcat gtcttacttt gacaagacgc cagcaggttc
    60361 tatcgtttct cgtttgacca acgataccga gacgattagt gatatgtttt ctgggatttt
    60421 atccagcttt atctcagcag tttttatctt tctgacaacc ctttatacca tgttggtgct
    60481 ggattttcgt ttgacggctt tagtcttgct ctttctcccc ttgattttcc ttttggtcaa
    60541 tctctatcga aaaaagtcag tgaaaatcat cgagaaaacc agaagtctct tgtcagatat
    60601 caatagtaag ctggcagaga atatcgaggg aatcaggatt attcaggctt ttaatcaaga
    60661 gaagcgcctg caggcagaat ttgatgaaat caaccaagag cacttggcct atgccaaccg
    60721 ttctgtagcc ttggatgccc tctttttgag acctgccatg agtttgttga aacttctagg
    60781 ttatgctgtc ttgatgacct attttggcta tcgtggtctt tctatcggga taacggccgg
    60841 gaccatgtat gcttttatcc agtacatcaa ccgcctcttt gaccctttga ttgaggtgac
    60901 gcaaaacttt tcaacactgc aaacgtctat ggtttctgca ggccgtgtct ttgccttaat
    60961 cgatgagagg acctatgagc cccttcaaga aaatgggcaa gccaaagtca aagaaggcaa
    61021 tatccgtttt gaacatgtgt gtttctcgta tgacggtaaa catccgattc tggatgacat
    61081 ttctttctct gttaataagg gtgaaaccat tgcctttgta ggtcatacag gttcagggaa
    61141 atcgtctatt atcaatgtcc tcatgcgctt ttatgaattc cagtcaggga gagttctctt
    61201 ggatgatgtg gatatcaggg atttcagtca agaagagctg agaaaaaaca tcggtttggt
    61261 tttacaggaa cccttcctct atcatggaac tattaagtcc aatatcgcca tgtaccaaga
    61321 aatcagtgat gagcaggttc aggctgcggc agcctttgtg gatgcagatt cctttattca
    61381 agaacttcct caggggtacg actcccctgt ttccgagcgt ggttcgagct tctctactgg
    61441 gcagcgccag cttcttgcct ttgctagaac agtcgccagc cagcctaaaa tcctgatttt
    61501 ggatgaagcg acagccaata ttgactctga aacagaaagt ttggttcaag cttctctggc
    61561 gaagatgaga cagggccgaa caactattgc tatcgctcac cgcctttcta ctattcaaga
    61621 cgccaactgc atctatgtct tggataaggg acgcattatc gagagtggaa cccatgagga
    61681 actcttgact ctgggaggaa cctatcacaa gatgtatagt ttgcaggcag gggccatggc
    61741 ctatactctt tgaaaatctc tttaaaccat gtcagcttta tctgcaatct caaagctgta
    61801 ctttgatttt cattgagtac tagaaggaaa tccttcaaat tacagatttc tttcaccgcc
    61861 ttttccattt tgtggtataa tgaaaaatgt tgacaaatag tataataaaa acaaaggaga
    61921 acagcatgct gaaatgggaa gacttgcctg tggaaatgaa atcaagcgag gttgagtctt
    61981 actaccagct tgtctctaaa aggaagggtt cgctgatttt caagcgttgc ttggactggg
    62041 ttttggcctt ggtcttactg gttctaactt ctcccatctt tctcatcttg agcatttgga
    62101 tcaagttgga tagcaagggg ccagtgattt acaagcaaga gcgtgtgacc cagtacaacc
    62161 gtcggttcaa gatttggaag ttccgtacca tggtgacgga tgcggataaa aaaggaagtc
    62221 tggtgacttc tgctaacgat agccgtatta ccaaggttgg aaatttcatc cgacgtgtcc
    62281 gtttggacga actgcctcag ttggtcaatg tccttaaagg tgagatgtcc tttgtcggta
    62341 cacgacctga agtgccacgt tatacagagc agtatagccc tgaaatgatg gcaaccttgc
    62401 tcttgcaagc aggaattacc tctccagcca gcatcaacta caaggatgag gacaccatca
    62461 tcagtcaaat gacggagaaa ggtctgtcag ttgatcaggc ctatgtggag catgttcttc
    62521 ctgaaaagat gcgctataac ctcgcctatc tccgagagtt tagtttcttt ggggacatca
    62581 aaatcatgtt tcaaaccgtg tttgaggtac taaaataaag tagtcataag aaaatgagta
    62641 cagataaaag gagcaaatca atgccaaatt acaatattcc attttcaccg cctgatatca
    62701 cagaagcaga aattgctgaa gtagcggata ccctgcgttc tggttggatc acaacaggtc
    62761 ctaaaacaaa agaactggag cgccgcttgt ctctttacac acagacacct aagactgttt
    62821 gtctcaactc tgcgacagcc gctctggagt tgattttacg cgttttggaa gtgggacctg
    62881 gtgatgaagt catcgttcca gccatgacct atacggcttc atgtagtgtc attacgcacg
    62941 tgggagcaac ccctgtcatg gtggatatcc aagcagatac gtttgagatg gactatgacc
    63001 tgcttgagca agctatcact gagaaaacta aggtgattat cccagtagag ctcgcaggga
    63061 ttgtttgcga ttatgaccgt ttgttccaag tcgtggagaa aaaacgtgac ttctttaccg
    63121 cttcaagcaa gtggcaaaag gcctttaacc gtattgtcat tgtctctgat agtgcccacg
    63181 ctttgggatc tacttataaa ggacaacctt ctggttctat cgctgatttt acttccttct
    63241 cattccatgc tgttaagaac tttacaacgg cagaaggtgg aagtgcgact tggaaagcca
    63301 atccagtgat tgatgacgaa gagatgtaca aggaattcca aatcctttcc cttcacgggc
    63361 aaactaagga tgctcttgcc aagatgcaac tggggtcatg ggaatacgat atcgttacac
    63421 cagcctataa gtgcaacatg accgatatca tggcttcact tggtttggta caattggacc
    63481 gctatccaag tttgttgcaa cgccgtaagg acattgtgga ccgctatgat agtggttttg
    63541 caggttctcg catccatcct ttggcacaca agactgaaac tgtcgaatct tcacgccacc
    63601 tctacatcac ccgtgtagaa ggagcaagcc tagaagaacg caacctcatc atccaagaat
    63661 tggctaaagc aggaattgca agtaatgttc actacaaacc gcttcctctc ttgacagcct
    63721 ataagaatct tggatttgat atgacgaact atcctaaggc ctatgccttc tttgagaatg
    63781 aaattaccct ccctcttcat actaaattaa gcgatgaaga agtagactat atcattgaga
    63841 ctttcaaaac agtttctgaa aaagtgctaa ctttatcaaa aaaatgacaa actacagtca
    63901 agcgaaagtg atcctgtccc taaaaagtct aattgagtgt aaaaactgtt gttttcaatt
    63961 gataatagtt tacacctgta gttgaggcct ctttctcctc agagagagaa tttttatagg
    64021 attttccttt cttgtgggag tcccgtggtt tgaaataaga tgtgagcaat ttggtatagc
    64081 atttagaatc cttactagac atcatttaga aaatctagtg tcttgttcta gttttcaatt
    64141 caccctattt tttgaaagac gtgagtttcc atgagtgaga ttgtggaaac tagcgtcttt
    64201 tttttgtttt cagaatattg ttcaaagttt tgtgcctgtc tttcatgttc tagtcattct
    64261 tttgcatgat agaatttata gcatgttgat attataataa cgcaaatatc ccatatgttt
    64321 agtgatgctt gctatacatc attagatctc ctgcgagaca atctataaaa cacttgtcta
    64381 cgattaccta tatgccctat tccagtattt tagaagcact gcatctattt ttatcgaggt
    64441 taaatctagc ttttatagaa ggtctattta agaaatatat tgtagtgttt tagtttcaat
    64501 ccgccatatg agcgatattc aggtaaatat ccctggcgaa tgcttgtatg acaaggtatt
    64561 tgttctttca tttataattt acaacatatc aacaaattta aatatagtaa atgggatatt
    64621 ttatattcaa gctaagaaag atagcatcac ttttgaatgg aaggctaaag agcaaactag
    64681 gaagttggcc atagatagct caaaaccctg ctttgaggtt gtagatatag taaaatgaaa
    64741 caagaatagg acaaattgat cgggacagtt aaatcgattt ctaacaatgt tttagaagta
    64801 gaggtgtact attatagttt cagtctacta tagaactgac caagtcagta acctagactt
    64861 agggcaaggc ggcactgacc tagtttgaag agatttccga agagtataaa ttttaatatt
    64921 ttcttgtgtt attccttgac aattcaattt ggaaaatata tgataaagat aatgacagcg
    64981 gtgtcattct atctatttta agaaaagtaa taatcaattg ttaaaaatag taaaaaaatt
    65041 ggaggttctg atgaaatatt ttgttcctaa tgaggtattc agtattcgta aattaaaggt
    65101 ggggacttgc tcggtactat tggcaatttc aattttggga agccaaggta ttttatcgga
    65161 tgaagttgtt actagttctt caccgatggc tacaaaagag tcttctaatg caattactaa
    65221 tgatttagat aattcaccaa ctgttaatca gaatcgttct gctgaaatga ttgcctctaa
    65281 ttcaaccact aatggtttag ataattcgtt aagtgttaat agtatcagct ctaatggtac
    65341 tattcgttcc aattcacaat tagacaacag aacagttgaa tctacagtaa catctactaa
    65401 tgaaaataag agttataagg aagatgttat aagtgacaga attatcaaaa aagaatttga
    65461 agatactgct ttaagtgtaa aagattatgg tgcggtaggt gatgggattc atgatgatcg
    65521 acaagcaatt caagatgcaa tagatgctgc agctcaaggg ctaggtggag gaaatgtata
    65581 ttttcctgaa ggaacttatt tagtaaaaga aattgttttt ttaaaaagtc atacacactt
    65641 agaattgaat gagaaagcta caattctaaa tggtataaat attaagaatc acccttccat
    65701 tgtttttatg acaggtttat ttacggatga tggtgcgcaa gtagaatggg gcccaacaga
    65761 agatattagt tattctggtg gtacgattga tatgaacggt gctttgaatg aagaaggaac
    65821 taaagcaaaa aatctaccac ttataaattc ttcaggtgca tttgctattg ggaattcaaa
    65881 taacgtaact ataaaaaatg taacattcaa ggatagttat caagggcatg ctattcaaat
    65941 tgcaggttcg aaaaatgtat tagttgataa ttctcgtttt cttgggcaag ccttacccaa
    66001 aacgatgaag gatgggcaaa tcataagtaa ggagagcatt cagattgaac cattaactag
    66061 aaaaggtttt ccttatgcct tgaatgatga tgggaaaaaa tctgaaaatg tgactattca
    66121 aaattcctat tttggcaaaa gtgataaatc tggggaatta gtaacagcaa ttggcacaca
    66181 ctatcaaaca ttgtcgacac agaacccctc taatattaaa attttaaata atcattttga
    66241 taacatgatg tatgcaggtg tacgttttac aggattcact gatgtattaa tcaaaggaaa
    66301 tcgctttgat aagaaagtta aaggagagag tgtacattat cgagaaagcg gagcagcttt
    66361 agtaaatgct tatagctata aaaacactaa agacctatta gatttaaata aacaggtggt
    66421 tatcgccgaa aatatattta atattgccga tcctaaaaca aaagcgatac gagttgcaaa
    66481 agatagtgca gaatatttag gaaaagtatc agatattact gtaacaaaaa atgtaattaa
    66541 taataattct aaggaaacag aacaaccaaa tattgaatta ttacgagtta gtgataattt
    66601 agtagtgtca gagaatagta tattcggtgg taaagaagga attgttattg aggattcaaa
    66661 gggtaaaata accgttttaa ataaccaatt ttataattta tccggtaagt atatatcatt
    66721 catcaaatct aatgcaaacg ggaaagaacc tgttatacgt gatagcgatg gtaatttcaa
    66781 tattgtaacg gagaatgggc tttacaaaat tgtaacaaat aatttaagtg ataaaaacga
    66841 aaaagaaaaa aacaaagagg aaaaacaatc taattcaaat aatgtaattg atagtaacca
    66901 gaagaacgga gagtttaact caagtaaaga taatagacaa atgaatgaca agatcgacaa
    66961 taaacaagat aataagacag aagaagtaaa ctataaaata gttggagatg gcagagaaac
    67021 tgaaaatcat attaataaat ctaaagaaat agtagatgta aaacaaaaat taccaaagac
    67081 tggttcgaac aagattatgg aactattctt aacagtgaca ggaattggtt tacttttgac
    67141 actaaaaggg ttgaagtatt atggtaaaga taaataaaat ttgttcgata caaggaagtt
    67201 ccgtagaaaa tgaggatatt gtaggttcac aaaatcagta tttttggatt attggtggag
    67261 ctacagattt atataattct aaagaggaga taggttattc agtctcagaa gttgtacata
    67321 ttttatcaga aagtttgtcg gttaattgta aagaatcaaa aactcttaaa caaatatttg
    67381 aaactgcttt actcgaggtt aaagatgaaa tcggtttaaa ctcatatgaa ttaacagagt
    67441 ataataaaat gaaataataa tagga
//
LOCUS       DAVLBE010000004        65973 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.004, whole genome shotgun sequence.
ACCESSION   DAVLBE010000004 DAVLBE010000000
VERSION     DAVLBE010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 65973)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 65973)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..65973
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.004"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(269..406)
                     /locus_tag="VXB91_000233"
     CDS             complement(269..406)
                     /locus_tag="VXB91_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
                     /protein_id="HEV0469749.1"
                     /translation="MAEEVLNLQLVSVQVDETDEVDGMRFSTFSTNRCGNWSAFSWEN
                     C"
     gene            complement(608..1195)
                     /locus_tag="VXB91_000234"
     CDS             complement(608..1195)
                     /locus_tag="VXB91_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0469750.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCIGELTILQILYGSSLIS
                     FLWMYGQRKQAHKVNMKSRMKWLGVEFVSLLIISLCFSLIHAQGSTNQANLIGLQHQI
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALAHHTGTILAWCLYV
                     SLGMFLGMVRYKSDLWGSMGLHLVWNLLVYSLLLF"
     gene            complement(1288..1431)
                     /locus_tag="VXB91_000235"
     CDS             complement(1288..1431)
                     /locus_tag="VXB91_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0469751.1"
                     /translation="MAERFWENLSIILAERNISWIELTRKMFAGEFHYPSELNRLYQK
                     IRH"
     gene            complement(1444..1824)
                     /locus_tag="VXB91_000236"
     CDS             complement(1444..1824)
                     /locus_tag="VXB91_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEV0469752.1"
                     /translation="MIDLYLSKNRQRNQLLLDFFQNYGIEVSCHSVSEMTKDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFVEIILKNPELTIRLPLAVSNKRVYPSLNLE
                     EARALLPRDTKQLIYMAQTHYLSN"
     gene            complement(1817..2157)
                     /locus_tag="VXB91_000237"
                     /pseudo
     CDS             complement(1817..2157)
                     /locus_tag="VXB91_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812122.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(2171..2419)
                     /locus_tag="VXB91_000238"
                     /pseudo
     CDS             complement(2171..2419)
                     /locus_tag="VXB91_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648301.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
     gene            complement(2419..2589)
                     /locus_tag="VXB91_000239"
     CDS             complement(2419..2589)
                     /locus_tag="VXB91_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001168336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0469753.1"
                     /translation="MQKEGQSSRQFVKSHLMTIMGVDIVKATQLVDEMEQVGLIRFDE
                     FGNVGILVLEGQ"
     gene            complement(2776..3144)
                     /gene="rplL"
                     /locus_tag="VXB91_000240"
     CDS             complement(2776..3144)
                     /gene="rplL"
                     /locus_tag="VXB91_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HEV0469754.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKAKLEEAGASVTLK"
     gene            complement(3220..3720)
                     /locus_tag="VXB91_000241"
     CDS             complement(3220..3720)
                     /locus_tag="VXB91_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HEV0469755.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     misc_feature    complement(3759..3894)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(3970..5229)
                     /locus_tag="VXB91_000242"
     CDS             complement(3970..5229)
                     /locus_tag="VXB91_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HEV0469756.1"
                     /translation="MKVFQHVNIVTCDQNFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPNGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQLQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKVLGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLTVEL"
     gene            complement(5576..7324)
                     /locus_tag="VXB91_000243"
     CDS             complement(5576..7324)
                     /locus_tag="VXB91_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0469757.1"
                     /translation="MKRQTVNQTLKRLAVDLANHPFLLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSPVFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFADRQGNGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKRSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGSA
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     SDQVKGAISFKHVSFGYHPEKILIKDLSIDIPAGSKIAIVGPTGAGKSTLINLLMRFY
                     PISSGDILLDGQSIYDYTRASLRQQFGMVLQETWLTQGTIHDNIAFGNPEASREQVIA
                     AAKAANADFFIQQLPQGYDTKLENAGESLSVGQAQLLTIARVFLAIPKILILDEATSS
                     IDTRTEVLVQDTFAKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYGNHQELMDR
                     KGKYYQMQKAAAFSSE"
     gene            complement(7326..9050)
                     /locus_tag="VXB91_000244"
     CDS             complement(7326..9050)
                     /locus_tag="VXB91_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0469758.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLPKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISAELTFWFL
                     VMVAILTIVIVGLSRLVNPLYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFWSSLLTPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNQSYISAKRIEEVFAESPENIHSELEQKQVTSGRVLQV
                     QELTFTYPDAAQPSLRYISFDMTQGQILGIIGGTGSGKSSLVQLLLGLYPIDKGSIDL
                     YRDGSSPRNLEQWRSWIAYVPQKVELFKGTIRSNLTLGLNQEVTDQELWQALEIAQAK
                     DFVSDKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFLILDDATSALDTITESK
                     LLKAIRENFPNMSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYREIN
                     ASQHGKED"
     gene            complement(9108..10046)
                     /gene="msrB"
                     /locus_tag="VXB91_000245"
     CDS             complement(9108..10046)
                     /gene="msrB"
                     /locus_tag="VXB91_000245"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEV0469759.1"
                     /translation="MAEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLI
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            complement(10191..10265)
                     /locus_tag="VXB91_000246"
                     /pseudo
     CDS             complement(10191..10265)
                     /locus_tag="VXB91_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829418.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(10341..11210)
                     /locus_tag="VXB91_000247"
     CDS             complement(10341..11210)
                     /locus_tag="VXB91_000247"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HEV0469760.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTQGVRVEAK"
     gene            complement(11212..12498)
                     /locus_tag="VXB91_000248"
     CDS             complement(11212..12498)
                     /locus_tag="VXB91_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HEV0469761.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVAHKGIRNITPEDVAVAQEFGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILAPDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            complement(12649..13386)
                     /gene="mecA"
                     /locus_tag="VXB91_000249"
     CDS             complement(12649..13386)
                     /gene="mecA"
                     /locus_tag="VXB91_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HEV0469762.1"
                     /translation="MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVVFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            complement(13586..14620)
                     /locus_tag="VXB91_000250"
     CDS             complement(13586..14620)
                     /locus_tag="VXB91_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEV0469763.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPKESAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            complement(14649..16082)
                     /locus_tag="VXB91_000251"
     CDS             complement(14649..16082)
                     /locus_tag="VXB91_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HEV0469764.1"
                     /translation="MIDGKRLLFSLTIVSYALTLVSGIVYLFNNNNVSLLSTLLFLLV
                     SSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVMV
                     SILGLTTGGILARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRLF
                     ERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSFI
                     AANTIHLAIGTRNPFILSILFAFVYYFMREQTEKGKWIGFKEKLAIFVGSPILMLAMG
                     VLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPVL
                     DYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYIM
                     ELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSES
                     FFNLFTMQFWGIVLVIIFVAKMLTKEN"
     gene            complement(16098..17084)
                     /locus_tag="VXB91_000252"
     CDS             complement(16098..17084)
                     /locus_tag="VXB91_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV0469765.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQKQTYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATALSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAEKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFEAYS
                     QIHRFLKGHAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            complement(17086..18189)
                     /locus_tag="VXB91_000253"
     CDS             complement(17086..18189)
                     /locus_tag="VXB91_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEV0469766.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDPEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLARRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYTSKLQTIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYGIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTNVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFDVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            complement(18179..19024)
                     /locus_tag="VXB91_000254"
     CDS             complement(18179..19024)
                     /locus_tag="VXB91_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEV0469767.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVAFCKEHDLLCYLCGGGAIGALR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSHKDFVDRNLFITIRDKET
                     TCIKPYQQDLDLPHGLALDVLPLDYYPKNPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSRILLGLTPKSLCYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFLPFEGTEMPIPIGYDVYLRTAFGDYMTPPPADKQVPHHDAVIADMDKSYTEYK
                     GEYGG"
     gene            complement(19303..20574)
                     /gene="psr"
                     /locus_tag="VXB91_000255"
     CDS             complement(19303..20574)
                     /gene="psr"
                     /locus_tag="VXB91_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HEV0469768.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFAYLQEKLTLAR
                     GNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSFPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDEADYGRTKRQQQVLTA
                     ILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPELG
                     DWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            complement(20571..21419)
                     /gene="pheA"
                     /locus_tag="VXB91_000256"
     CDS             complement(20571..21419)
                     /gene="pheA"
                     /locus_tag="VXB91_000256"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEV0469769.1"
                     /translation="MKIAYLGPKGSFSHHVVQIAFPHEELQAFANITDVIKAYEQGLV
                     DYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAVAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWVLGAEKPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYTDKDLVHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            complement(21416..21892)
                     /locus_tag="VXB91_000257"
     CDS             complement(21416..21892)
                     /locus_tag="VXB91_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEV0469770.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDPNYLDMDALIEKRLGMSIANFFA
                     EKGEAAFRQVESEVLADLLQTDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLY
                     QRIAADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            complement(21885..23168)
                     /gene="aroA"
                     /locus_tag="VXB91_000258"
     CDS             complement(21885..23168)
                     /gene="aroA"
                     /locus_tag="VXB91_000258"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HEV0469771.1"
                     /translation="MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVITIQGVGMAGLKAPQNALNMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLRPIHY
                     ELPIASAQVKSALMFAALQAKGESVIIEKECTRNHTEDMLKQFGGHLSVDGKKITVQG
                     PQKLTGQKVVVPGDISSAAFWLVAGLIVPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EITEIDPVAKSSTLTVESSDLKGTEIGGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVADGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            complement(23260..23598)
                     /locus_tag="VXB91_000259"
     CDS             complement(23260..23598)
                     /locus_tag="VXB91_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HEV0469772.1"
                     /translation="MSNIYDSANELSRGLRGLPEYKAVKAAKDAIAADAEASKIFTEY
                     LAFQEEIQKLAHTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            complement(23609..24712)
                     /locus_tag="VXB91_000260"
     CDS             complement(23609..24712)
                     /locus_tag="VXB91_000260"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HEV0469773.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSETILDRIEDFKERLEVIGQAISKGDEEQIWNFFN
                     QAREQRQTMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITENTDYTVVIK"
     gene            complement(24722..25888)
                     /gene="aroC"
                     /locus_tag="VXB91_000261"
     CDS             complement(24722..25888)
                     /gene="aroC"
                     /locus_tag="VXB91_000261"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HEV0469774.1"
                     /translation="MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIESDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            complement(25898..26965)
                     /locus_tag="VXB91_000262"
     CDS             complement(25898..26965)
                     /locus_tag="VXB91_000262"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HEV0469775.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTELNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     VAEEKGLMPAGITQSITEMCQKFGLPVDYENWEVDKLYQALTHDKKTRGNTLKLVLVS
                     ELGSAIIHPVSLEEMKDYLVK"
     gene            complement(26984..27838)
                     /locus_tag="VXB91_000263"
     CDS             complement(26984..27838)
                     /locus_tag="VXB91_000263"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEV0469776.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGAYVAWEI
                     EASDLAETVANIRRYQMFGINLSMPYKEQVIPYLDKLSDEARLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLCALENVSELQARIAESDLLVNATSVGMDGQSSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIW
                     QSLTEKYQ"
     gene            complement(27828..28505)
                     /locus_tag="VXB91_000264"
     CDS             complement(27828..28505)
                     /locus_tag="VXB91_000264"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HEV0469777.1"
                     /translation="MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQFYQPDYIDFEYYSYKD
                     VFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            complement(28502..29665)
                     /locus_tag="VXB91_000265"
     CDS             complement(28502..29665)
                     /locus_tag="VXB91_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HEV0469778.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASDLENVNLKDQEVEVQGQEGN
                     FLGTAYLSQQNKGLGWFVSKDKVAFNQTFFETLFRKAKEKRNAYYQDDLTTAFRLFNQ
                     EGDGFGGLTVDLYGDYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGFDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLAMGKSLLN
                     MFSYTAAFSVAAAMGGASQTTSVDLAKRSRELSQAHFQANGLSTDEHRFIVMDVFEYF
                     KYAKRKDLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            complement(30350..31984)
                     /locus_tag="VXB91_000266"
     CDS             complement(30350..31984)
                     /locus_tag="VXB91_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0469779.1"
                     /translation="MRLKVIKKLVDINILYSSQEANLANLRKKQAKNPGKKVNVSARV
                     LSSYIFSSLLMLICFSNIAIHFPFEEMPIYFSSMVAILLVLAFSTSFTAFYNVFYESK
                     DLASYRPYAFKESEIIMAKGLSVLLPALTGIVPILAYFLALYISLAPSLWLGLPLMLL
                     SLTLLFVSVTLVTVVAVHFLAQTRVFRKYQSIFSNVMIGIGVLIPLIFIFFLQSTFGS
                     IVDKVRDIPFLLYPLHIFYKIAVEPFSTEALVGLLAWIGLTLFLLYLTKKKVLPRFYD
                     VILLNSEEKVKKERRSKERISTTKKGFFRMVLRYHLTLLGQGTGVITVLFTSAFLPYL
                     MMISLISKIRDSQIVPDIHPPYWLPLFFVGVFIAVVNNNITSLHSIALSLERENVDFL
                     KSLPFDFARYVKVKFWIIFAVQSFLPVLTLLGLSLYLGLSILSMIYLLVVWIIASVIL
                     SCHHYFKDVKNLSTNWSSITDLVNRSNGIVAIVLLFIYSAILMALVIGSIFLVQSLSP
                     ILAINLGVGALIVLLALAIFGYHYYLSRILAEIEKR"
     gene            complement(31965..32714)
                     /locus_tag="VXB91_000267"
     CDS             complement(31965..32714)
                     /locus_tag="VXB91_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0469780.1"
                     /translation="MIEFQNVSKLYGDKEALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQELSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLSRSDLEASLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSDPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCDRIAILKKGHLIYCGKVED
                     LRKDHPDQFLESIYLSLAGRKEEVADASQGH"
     gene            32893..34347
                     /locus_tag="VXB91_000268"
     CDS             32893..34347
                     /locus_tag="VXB91_000268"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HEV0469781.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAENAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKAQGIQPMADVVL
                     NHKAAADHREAFQVIEVDPVDRTVELGEPFTINGWTSFTFDGRQDTYNGFHWHWYHFT
                     GTDYDAKRSKSGIYLIQGDNKGWANEELVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKAVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQQDFKEILDRLLAIR
                     KDLAYGEQNDYFDHANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            complement(34437..37055)
                     /gene="alaS"
                     /locus_tag="VXB91_000269"
     CDS             complement(34437..37055)
                     /gene="alaS"
                     /locus_tag="VXB91_000269"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HEV0469782.1"
                     /translation="MKQLSSAQVRQMWLDFWATKGHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPCITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLTSPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGS
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESVFNYNASQLSSKLVAIVADNAEVEAVSEGTASLIFAETSFYAEMGGQVA
                     DYGQILDESGKVVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLAIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVGNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAVAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDVKEVNGHRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIIDGRGGGKPDMAMAGGS
                     NQAKIQELLDAVAGKL"
     gene            complement(37077..37562)
                     /locus_tag="VXB91_000270"
     CDS             complement(37077..37562)
                     /locus_tag="VXB91_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related family protein"
                     /protein_id="HEV0469783.1"
                     /translation="MKTFLVKQKFRLGGERFAIKNDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSEISKEILTLLPRFEIQLRDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEMLESQS
                     H"
     gene            complement(37837..38076)
                     /locus_tag="VXB91_000271"
     CDS             complement(37837..38076)
                     /locus_tag="VXB91_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0469784.1"
                     /translation="MKMSTFFKKSFWPTFMIVNQTVILFHLKDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILKK"
     gene            complement(38337..39407)
                     /locus_tag="VXB91_000272"
     CDS             complement(38337..39407)
                     /locus_tag="VXB91_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV0469785.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYETFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIKGIENIGPEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKPEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDLQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQNS
                     AYAFINFMLKPENALQNAEYVGYSTPNLPAKELLPEETKEDKAFYPDVETMKHLEVYK
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            complement(39404..40177)
                     /locus_tag="VXB91_000273"
     CDS             complement(39404..40177)
                     /locus_tag="VXB91_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0469786.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSFTGFSWTH
                     FETMFGDGRLMLILAQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIIAGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            complement(40174..40980)
                     /locus_tag="VXB91_000274"
     CDS             complement(40174..40980)
                     /locus_tag="VXB91_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0469787.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWLMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            complement(40961..42118)
                     /locus_tag="VXB91_000275"
     CDS             complement(40961..42118)
                     /locus_tag="VXB91_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0469788.1"
                     /translation="MKKPIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRKIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFESEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            complement(42278..43183)
                     /gene="murB"
                     /locus_tag="VXB91_000276"
     CDS             complement(42278..43183)
                     /gene="murB"
                     /locus_tag="VXB91_000276"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HEV0469789.1"
                     /translation="MSVREKMLEILEGIDIRFKEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARLVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESK"
     gene            complement(43295..44047)
                     /locus_tag="VXB91_000277"
     CDS             complement(43295..44047)
                     /locus_tag="VXB91_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
                     /protein_id="HEV0469790.1"
                     /translation="MTIHIIITMLLLLAFLIGSIWFAKKKYQINLAVLGLGAVAFFVS
                     SQILEKLVHILILHPQKDGSIALLQDHPLIYIIYGLAMAAFFEETARLVFFKWLEKKR
                     SLEKADALAYGLGHGGLELIFLGLISLLNLYIVLSAVQTQNPQVMQLLSENMLKTIQS
                     LSVWQIYLLGFERILALGFQLLLTVWVYQAVRQKKWIYLLAAYGLHAFFDLAPSLFQV
                     GWLTNPVLVEVILALELVLVAYGTKEIFCKKS"
     gene            complement(44057..44788)
                     /gene="budA"
                     /locus_tag="VXB91_000278"
     CDS             complement(44057..44788)
                     /gene="budA"
                     /locus_tag="VXB91_000278"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HEV0469791.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKGSGDQPEIVEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELKERIESYYDGENLFRSIKIRGEFSHMHVRMIPKSTPDTKFADVATHQPEYSRDNV
                     AGTIVGFWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            44930..46201
                     /locus_tag="VXB91_000279"
     CDS             44930..46201
                     /locus_tag="VXB91_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HEV0469792.1"
                     /translation="MKKQSKYKEVVSYLKNGIESGRFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFEQALYCKANQLVLTSGTQQALFILSQISFP
                     SQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLKELERHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRSILNLAAKYDVYIVEDDYLGDLDSKKGQTFHYLDTEEHVIYI
                     KSFSTSLFPALRITALILPNAIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQPGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            complement(46221..47036)
                     /locus_tag="VXB91_000280"
     CDS             complement(46221..47036)
                     /locus_tag="VXB91_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEV0469793.1"
                     /translation="MKSKKWIFVLCNFLASFFLVACQSGSNGSQSAVEAIKQKGKLVV
                     ATSPDYAPFEFQSLVDGKNQVVGADIDMAQAIADELGVKLEISSMSFDNVLTSLQTGK
                     ADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTSLESANIAAQKGT
                     VPESMVKEQLPKAQLTSLTNMGEAVNELQAGKVDAVHMDEPVALSYAAKNAGLAVATV
                     SLKMKDGDANAVALRKNSDDLKEVVDKVIQKLKDEGIYQSYLEKAASLTEVEE"
     gene            complement(47193..47846)
                     /gene="phoU"
                     /locus_tag="VXB91_000281"
     CDS             complement(47193..47846)
                     /gene="phoU"
                     /locus_tag="VXB91_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEV0469794.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            complement(47858..48616)
                     /gene="pstB"
                     /locus_tag="VXB91_000282"
     CDS             complement(47858..48616)
                     /gene="pstB"
                     /locus_tag="VXB91_000282"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEV0469795.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLDPQHKETEDYITGKFG"
     gene            complement(48629..49432)
                     /gene="pstB"
                     /locus_tag="VXB91_000283"
     CDS             complement(48629..49432)
                     /gene="pstB"
                     /locus_tag="VXB91_000283"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEV0469796.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            complement(49443..50327)
                     /gene="pstA"
                     /locus_tag="VXB91_000284"
     CDS             complement(49443..50327)
                     /gene="pstA"
                     /locus_tag="VXB91_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEV0469797.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            complement(50317..51234)
                     /gene="pstC"
                     /locus_tag="VXB91_000285"
     CDS             complement(50317..51234)
                     /gene="pstC"
                     /locus_tag="VXB91_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEV0469798.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGTWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            complement(51234..52112)
                     /gene="pstS"
                     /locus_tag="VXB91_000286"
     CDS             complement(51234..52112)
                     /gene="pstS"
                     /locus_tag="VXB91_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HEV0469799.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            complement(52686..53990)
                     /locus_tag="VXB91_000287"
     CDS             complement(52686..53990)
                     /locus_tag="VXB91_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HEV0469800.1"
                     /translation="MQFPEGFVEKYKEILGDEARDFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDAMDYWSLDYPSQCASLQREILEDAVTMLAEGGRLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQTFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKPSQVEQSVEIGQEAFVKYAAGEI
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            complement(53991..54764)
                     /locus_tag="VXB91_000288"
     CDS             complement(53991..54764)
                     /locus_tag="VXB91_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HEV0469801.1"
                     /translation="MESKFEFAKELVKKAGQYILDHMQEDLRVETKSSPTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRPLAPFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRAVLGVRVYGSAAISFAKILSGRLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            complement(54754..55032)
                     /locus_tag="VXB91_000289"
     CDS             complement(54754..55032)
                     /locus_tag="VXB91_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HEV0469802.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGEGKISLGK"
     gene            complement(55032..55433)
                     /locus_tag="VXB91_000290"
     CDS             complement(55032..55433)
                     /locus_tag="VXB91_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HEV0469803.1"
                     /translation="MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQH
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            complement(55643..56260)
                     /locus_tag="VXB91_000291"
     CDS             complement(55643..56260)
                     /locus_tag="VXB91_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HEV0469804.1"
                     /translation="MKTKLTFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLALVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYESFFGYLCLKSRRK"
     gene            complement(56250..57023)
                     /locus_tag="VXB91_000292"
     CDS             complement(56250..57023)
                     /locus_tag="VXB91_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HEV0469805.1"
                     /translation="MKYKGYLIDLDGTIYKGKDRIPAGETFVHELQKRDIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEVIK
                     AAGYVEDKEKPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            complement(57034..57771)
                     /locus_tag="VXB91_000293"
     CDS             complement(57034..57771)
                     /locus_tag="VXB91_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000524807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HEV0469806.1"
                     /translation="MGLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEEYNLVWIIVEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAEQ
                     ELIHMMATFVLMDRDSRKVHVVEPEIVAPYQSDFDKKLIRGPKYESLEEPISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSAVERTG
                     LESKHEITSDGVINAQAIITWQEIKKA"
     gene            complement(57776..58906)
                     /locus_tag="VXB91_000294"
     CDS             complement(57776..58906)
                     /locus_tag="VXB91_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HEV0469807.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLDAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     HGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            complement(58990..59379)
                     /locus_tag="VXB91_000295"
     CDS             complement(58990..59379)
                     /locus_tag="VXB91_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEV0469808.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYAFQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIDITEE"
     gene            complement(59395..59778)
                     /locus_tag="VXB91_000296"
     CDS             complement(59395..59778)
                     /locus_tag="VXB91_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HEV0469809.1"
                     /translation="MLEVAYILVALALIVFLVYLIITVQKLGRVIDETEKTIKTLTSD
                     VDVTLHHTNELLAKVNVLADDINVKVATIDPLFSAVADLSLSVSDLNDHARVLSKKAS
                     SAGSKTLKTGASLSALRLASKFFKK"
     gene            complement(59779..60567)
                     /locus_tag="VXB91_000297"
     CDS             complement(59779..60567)
                     /locus_tag="VXB91_000297"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HEV0469810.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFSLRVSQWLSVVLIGLGIMIVIYQNRKKAPYYITEEEK"
     gene            complement(60560..61495)
                     /locus_tag="VXB91_000298"
     CDS             complement(60560..61495)
                     /locus_tag="VXB91_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HEV0469811.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINTADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            complement(61625..61801)
                     /locus_tag="VXB91_000299"
     CDS             complement(61625..61801)
                     /locus_tag="VXB91_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HEV0469812.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            complement(61941..62648)
                     /locus_tag="VXB91_000300"
     CDS             complement(61941..62648)
                     /locus_tag="VXB91_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HEV0469813.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESDLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            62799..63827
                     /gene="queA"
                     /locus_tag="VXB91_000301"
     CDS             62799..63827
                     /gene="queA"
                     /locus_tag="VXB91_000301"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HEV0469814.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFY
                     SIIDMLEPGDALVMNDTRVLPARLYGQKVETGGHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQGIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKENGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKVVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHAIQEHYRFFS
                     FGDAMFIY"
     gene            complement(64488..64877)
                     /locus_tag="VXB91_000302"
     CDS             complement(64488..64877)
                     /locus_tag="VXB91_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV0469815.1"
                     /translation="MVKRRIRRGTREPEKVVVPEQSSIPSYPVSVTSNQGTDVAVEPA
                     KAVAPTTGWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGSMKVNQWFQVGGKWY
                     YVNTSGELAVNTSIDGYRVNDNGEWVR"
     gene            complement(64931..65623)
                     /locus_tag="VXB91_000303"
     CDS             complement(64931..65623)
                     /locus_tag="VXB91_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEV0469816.1"
                     /translation="MNTSFVHAADGIQYVRDDTRDKEEGIEYDDADNGDIIVKVATKP
                     KVVTKKISSTRIRYEKDETKDRSENPVTIDGEDGYVTTTRTYDVNPETGHVTEQVTVD
                     RKEATDTVIKVPAKSKVEEVFVPFATKYEADNDLSAGQEQEITLGKNGKTVTTITYDV
                     DGKSGQVTESTLSQKEDSQTRVVKKGTKPQVLVQEISIETEYLDGPTLDKSQEVEEVG
                     EIGKLLLLQSIL"
BASE COUNT        19609 a        14938 c        12265 g        19161 t
ORIGIN      
        1 ttctgtctaa ctattggggt gcagttcaat aaatcttgac ccgttaaatt tgtactgaat
       61 aaactaaatg aaacttttat cccactcact aatactatta tatcaaccca ctacagttga
      121 caaagagaca aaccagccta atggctaact tgtcttcaat caagagagga ttctgttccc
      181 cccatataag cactaacatt ccaacgtaca catattggaa cgacatccat aacttcagag
      241 aatccctaaa gtttacaatt taaatgaatt aacaattttc ccaactaaaa gcactccagt
      301 taccgcaacg gtttgtactg aatgtactaa atcgcattcc atcaacttca tctgtttcgt
      361 caacttgaac agatactaat tgaagattta atacttcttc tgccatagct agctcctcct
      421 atttaaattt ttgggattaa gtactttatc caccctcatt atactctctc caccagtaaa
      481 atgcaagcaa ttatacaatg ttgtcacata gaaaataatg tttccgtaac ttttcaaagt
      541 aacttccatc tctctcccaa aactggaagt tagttttaga agttacctaa aaatcaggtc
      601 acctatttta aaaaagcagc aaactataaa ctagtaggtt ccacaccaaa tgtagtccca
      661 tactgcccca taagtcagat ttatagcgca ccatacctaa aaacatccca agtgaaacat
      721 acaaacacca agctagaatg gttcctgtat gatgtgctaa ggcaaataaa acacttgtca
      781 aagcaactct gatatctaat tttctgacca aattccataa aatttctcga tacagaaatt
      841 cttcaaccat actcgcattg attaagaaca ataaaaatga aaaccaagga atttgatgtt
      901 gaaggccaat taagtttgct tgattcgtgc ttccttgagc atgaatcaga ctaaaacata
      961 gacttataat cagtaggcta acaaattcaa caccaagcca tttcatccta gatttcatat
     1021 tgaccttatg cgcttgtttg cgttggccat acatccataa aaaagaaatg agtgacgaac
     1081 catagagaat ctgtagtata gttaactcac cgatacaaag aaatttcaat aagtatagag
     1141 ataccaatag gacatttact tgttggaata tataaactgg aattattctt ttcatagtta
     1201 cctccgaaat aaatcttcat aatctaaatc taatacctgc acaatccttt ctacccatgg
     1261 actttgaggc attcattgtt ccatcttcta gtggcgaatc ttttgataca aacgattcaa
     1321 ttcacttgga tagtgaaact ctcccgcaaa catttttctg gttaactcaa tccagctgat
     1381 atttctttca gccaaaataa tggacaagtt ctcccaaaat cgttcagcca tattgcttct
     1441 cctttagtta gataaataat gtgtttgcgc catgtaaatc aattgtttcg tatctcttgg
     1501 caatagagct ctagcctctt ccaaattcag acttggataa actcgcttat ttgaaaccgc
     1561 aagaggaagt ctgatggtta gttcaggatt ttttaaaatt atctcaacga aatccgttaa
     1621 tcttagattg tcacggttct taaatcgtaa taaattggga gataaaaact caaaacaatc
     1681 tgaagaatag ctcatcatct caattaattt gtcctttgtc atttcagaaa ctgaatgaca
     1741 agatacctct atgccatagt tttggaagaa atctaaaaga agttgatttc tttgtctatt
     1801 tttacttaga tagagatcaa tcatgggaga cctcccaaag attcggttcc atttgatatt
     1861 ctgacacgat taaggaatct aataaattaa ggaatctaat aaatttgcga agttaatcgg
     1921 tttcttgtct tcatcataag cttttacagt tacttgggtt gtaagtattc cctcttttcc
     1981 ctcggctcga tagccttgtc catataaaac aaaaacgaga ttttgatgat catctacaaa
     2041 ggcatcaacc ccattcttta tgtcttgact ttcaaggaat tccataacgt tttgaagata
     2101 ggattcgtaa aatagtgggt agttatgttt tttatggtaa tcatctaaaa atgtcacttc
     2161 aaactcacat ggagagtaat tttgactttg aacagcctaa aagtgccatc aaatttgaat
     2221 tggaataaat caaataaata gccccatcct catcaatcca acctttgctc aaagacaact
     2281 ccaaccgatc ttttaaaact gagtaaacca ccttaacctc cagtttcata ttcttatacc
     2341 gttcactctc aaataaaagt ttggggagct tataataacg ctctgatgtc tgatattgat
     2401 tagcggtaat acgcttcatt attgtccctc caagactaaa attccaacat ttccaaattc
     2461 atcaaatcgg attaaaccta cttgttccat ttcatcaact aactgagttg cttttacaat
     2521 atcaactccc atgatagtca tgagatgact cttcacgaat tgacgtgatg actgtccttc
     2581 cttttgcata attacctccg aaacacaaaa aaaggggtag acaatctagt gtctaccccc
     2641 gaaagtttat taaaacaaaa atcctgccaa agaatttttg gcaggaaacc aaatcaattt
     2701 atcagtttct atcaatcgct tatcgctctc aaagactggt aaatagggat tccgcaatca
     2761 aattgcgata ctctattatt taagagtaac tgaagctcca gcttcttcca atttagcttt
     2821 gatttcttca gcttctgcag ttgcaacgcc ttctttaaca agtgctggtg caccgtcaac
     2881 aagttcttta gcttctttaa gaccaagacc agtgatttca cgtacaactt tgataacgcc
     2941 aacttttttg tcgcctgcag atgtcaattc aacgtcgaat gaatctttag cagcaccagc
     3001 atcagctgca tcagctgcag caacagctac aggagcagct gcagttacac caaattcttc
     3061 ttcgatagct tttacaaggt cgttcaattc aaggattgaa gcttctttaa tttcagcaat
     3121 aatgttttca atgttcaatg ccattgttat ttcctccaaa taagttttaa attttataat
     3181 agtttttttc gtagctaggc tacgctatgt agcttaagat taagccgcgt cttctttgct
     3241 ttctgcaacc gctttgactg caagagcaac gttgcgcact ggcgcttgaa gtacagaaag
     3301 gagcatagaa agaagtcctt cgcggtttgg aagagttgca agtgcaagaa tctcttcttt
     3361 agatgcgaca gcgccttcga ttgcaccacc tttaatttca agtgcttcag cgtttttaga
     3421 aaagtcgttc aagattttcg ctggtgcgat aacatcttca ttagaaaatg ctactgcaga
     3481 tggtccaaca aatacagatg caagatcttc aagaccagct ttttcagctg cacgacgcaa
     3541 gattgagttt ttaataactt tatactcaac ttcgcttcca cgaagctcac gacgaagaac
     3601 tgtatcttgc tcaactgtca aaccacgagc gtctacaacg acgatagatg cagcagcttt
     3661 cattttttca gctactacgt caactagttc cgctttttta gcaataattg cttcactcat
     3721 tagtgtgttc acctccgtaa ttattttgct tggggaattt ttcaaaaaga aaaacgcgcc
     3781 caaacctaga cacgaaagta caatacgctt ctttttacat gatacgtttt gtcctcggta
     3841 ggatatttat gagtcgatct cccctactgt cttaggcagt ttttttaaac cgtatataag
     3901 tatagcatag tcaaaaaaag aatgcaagat ttttgcaaac tttttttaaa atttttcgtg
     3961 atttttcttt taaagttcta ctgtcaggac ttgaccttgc ttaacaacct gttctccggc
     4021 gatataaaca tcatctacat cactagattt aactgcataa accaggtgag acagcatatt
     4081 ttcctgaggt tggagatgaa ttttcccttg tggttgaatg accagaaaat ctgcttgctt
     4141 gccgacttcc agacttccta tctgattttc cattccaagg accttagccc cttcgattgt
     4201 cagtaccttg agagctgttt cgattggaaa ctggctggca tccccacttt tcatcttctg
     4261 aagaagagct gcagtccttc cttcctcaaa catatctaga ttgttattgg aagcaaccga
     4321 gtcagtcgca attccgactg ctactcccgc tttttggagc tggataattg gagcaattcc
     4381 tgatgccagt ttgaggttac tgataggatt gtgggcgata gccacttgag aagatgccaa
     4441 gcgttcaatt tctctctcgt ttaattcgac cccgtgagca aatacggacg gatgatctaa
     4501 ataacccagt tcttcaagaa aagcaagggg gcgtttgccg tatcgtttga ggataattcc
     4561 tgactcctcc ttggtctccg ccacatggac atggagcgga atatttagct cttttgccat
     4621 ttccaaactc gcttccagca agtctctact gcagctatac ggagaatgag gtgctaccat
     4681 aaccttgaaa tttggatttt tatattttaa gatttcgtct atgatggatc gagttctgct
     4741 tatagtctca gcagttgttt ctgtctctga agaaaagaga gtcggagaaa aataacaacg
     4801 catcttggaa gttttcacca cctgataaat ttgctggata tccacaccat tgggattata
     4861 catatcgtta aaggttgttg ttcctgactg gagcatctct gtcagggctt ctttgaccgc
     4921 attggtagtc atgtcgggag taaactcaga ttctgctggc cagatatagt cattgagcca
     4981 ttcatggaga ttgctgtcat ctcggatccc tctcagacct gtcattgcag aatgggtgtg
     5041 acaattgacc aaaccaggca taatccaagc tccctgatag tctataatct gctcagcttg
     5101 ttctaaaaac gctggcttat cttgaccgac atagacgatt tgagaatcct tgactgctaa
     5161 gattccatca agataaacat ggaaattttg atcacaagtc acgatattta catgctgaaa
     5221 gactttcatt atagactcct tttttaaaag acaagttgta ctctcttcaa accacttcag
     5281 attcactttg ccgtaggtgt ggttactgac ttcgtcagtt ctatctgcaa cctcaaaaca
     5341 gtgttttgag ctgacttcgt cagttctatc tgcaacctca aaacagtgtt ttgaactgac
     5401 ttcgtcagtc ttatctacaa cctcaaagct gtgctttgag caacctacgg ctagcttcct
     5461 agtttgctct ttgattttca ttgagtatta cagtgaacaa tttttctagc tattgtaaca
     5521 aaaaagtcac tcgaaggcaa cttttttcgt ccataaactt tcaaaagaga atggcttatt
     5581 cagaactaaa agccgcagct ttttgcattt ggtaatactt accctttcta tccatgagtt
     5641 cttgatggtt accatattca acaatatcac catctactaa gacaagaatt aaatccgcat
     5701 cctgaatggt tgacaaacgg tgagcaatga tgaagcttgt gcggcccttc atgagttttg
     5761 caaaggtatc ctgtaccagc acttctgtcc gtgtatcaat ggaagaagtt gcctcgtcta
     5821 agataagaat ctttggaata gccagaaaga ctcgggctat ggtcaagagc tgagcttggc
     5881 cgacagagag agattctcca gcattttcca acttggtatc gtatccctgt ggcaactgtt
     5941 gaatgaaaaa gtctgcatta gctgctttgg cagcagcaat tacttgctct cgactggctt
     6001 caggattgcc aaaggcaata ttatcatgaa tggtcccttg tgtgagccag gtttcttgaa
     6061 gcaccatacc aaactgctgt ctcaatgatg ctcgtgtata atcataaatg gattgcccat
     6121 ccagcaagat atctcccgag ctaatgggat aaaaacgcat aaggagattg ataagagttg
     6181 attttccagc acctgtcgga ccaacgatgg ctatcttact accagctgga atatcgatag
     6241 acaagtcctt aatcaaaatt ttttcaggat ggtagccaaa agagacatgt ttaaaggaaa
     6301 tagctccctt aacttggtca ctggtcaaga cttccttacc tgtttcagcc acttcagggc
     6361 tatctaagac tccatagata cgctctacgc aagccagagc actttgcaac tcagctagca
     6421 ctgaagaaat atcgttaaag ggcttggtgt attgctgaac atagttcaaa aaagtcacta
     6481 aacgaccgac ggtcaaggct gaacccatca tgatacgata agctcctact ccagctaaaa
     6541 gggcataaat gagtgcattt acaaagcgag tcgaaggatt gaccgttgaa gaataaaaga
     6601 tggctgactg agaatagcct gagtagttgt catgagcctc acgcaatctt tggataaatt
     6661 ctgtttgagc attgaaggac tggattatag tctgctggct aagcgattct tcaatcaact
     6721 gagtctgaat tcccctcgtc tctgtttgct tctggaagag atgataggat ctcttggcaa
     6781 taaagcgtga aatcaccatg gacagtggcg tcaacagcaa gactaagaga gtcatgagga
     6841 gatgaatttg gagcatggct agaatactaa ccaaaatcat caaaacacca atgaaaaatt
     6901 ggttaaaaat catggtcaag ccagctgcca actgttcgat gtccgtggtt acacgactga
     6961 ccatctctcc attgccttgc cgatccgcaa aagcaatcgg taaccgatgg agtttatgga
     7021 tgattcgctc tcgtaaatct ctggtataag agaagattag acgattatag aggagaggat
     7081 tggcccattg tactagagta tttcctatta ccaccaagag catctggaga aaaatctgcc
     7141 aaaaaactgg tgatgaacca gccactagga cttggtcaat gacctgccca atcagaatag
     7201 gtagataaat tgataagcca acttgggcaa tagttcctag aaaggctagg aaaaggagga
     7261 agggatggtt tgctaaatct acggctaaac gtttgagcgt ctggtttaca gtttgtcgtt
     7321 tcattctagt cctcctttcc atgttgggat gcattgattt cacgatagac ttgactggat
     7381 ttcatcaagt catcgtgctt gccaacagct agcaactcac ctttttccaa gaggagaatc
     7441 tggtcagcca tctgtaaagt cgaggttcgt tgagagatca aaattaagct catgtttgga
     7501 aaattttctc taatagcttt caagagcttg gactcggtaa tggtgtccag tgctgaggtc
     7561 gcatcatcta ggatgagaaa cggagcctgg cgcaagactg ctcgtgcgat agacagcctt
     7621 tgtttttgtc cacctgagaa atttcgccct cctgcttcaa ctagagcatc caagagtcct
     7681 tccttatcac tgacaaaatc cttagcttga gcaatttcca aggcttgcca gagttcttga
     7741 tcagtcactt cttgatttaa acctaaagtc aagttggaac gaatagttcc cttaaaaagt
     7801 tcgacctttt ggggaacata agcaatccaa gaccgccact gctctaaatt acgaggacta
     7861 gatccatctc gataaaggtc aatgctcccc ttatctattg gataaagtcc aagtaagagt
     7921 tgcaccaagc ttgacttacc agaacccgtt cccccgatga tacctagaat ttgtccttga
     7981 gtcatatcaa aggaaatgta tctcagagaa ggctgggccg catcaggata ggtaaaagtc
     8041 aattcttgga cttgtaaaac ccgaccactg gtaacttgct tttgttctaa ttctgaatgg
     8101 atgttttcgg gagattccgc aaagacctcc tcgattcgct tggctgagat ataggactgg
     8161 ttgagagaat ttatcaacat ggctagcttg accaattcca ccaaaatctg taagaggtaa
     8221 ttgataagag caatgagagc accttgactg agcactcctc cttgaattga aatatagcct
     8281 tgccagataa taacgagaag agttccattg acaatcagat aggtcagagg tgttaataaa
     8341 ctagaccaga aacctgtctt ttcttgtaat ctagcataaa cttggttaag ggtttgaaaa
     8401 atctgtaact ctcgtttttc ttgaccaaaa gcacgaataa cccgcatccc ttgcaattgc
     8461 tggcgcgttt cctgaaccag ttggtccgtt ttctttctga gactactgta gagaggattg
     8521 accaatcgag ataaccctac aatgacaatg gtcaaaatgg caaccatgac taagaaccag
     8581 aaagtcaact cagctgagat tcgataagcc ataaaaatgg caccaaaaac gataatgggc
     8641 gctcgtaaaa agagacgcag gaattgattg ataccagtct gaatctggta ggtatccgaa
     8701 gtcaagcgag taaccaaact agaagttgtc agacggtctc tgctgtcctt tggcaaggaa
     8761 agaatatgac gataaagatc gtttgtcaat tccttagcaa aacctactgc tgcctttgct
     8821 gagtaaaatt gagctatcaa ggccactaaa acgccaatta ctgcaaagat aaggagcagg
     8881 ccaatctgca tccagagatg accttgatct ccctgaggta aagattggtc aacaatccca
     8941 gcaatcacca tgggaaccaa gagctcaaaa acagcttcta acagcttgaa caagggggct
     9001 aaaattgatt ccttgatgta gggtttgaag taagataata ggtgtttcat aaatcccttc
     9061 tattcatatt ctagaaatga agaaagtggg aagccccact ctctgtttta tttgtttaag
     9121 taaggcaata gatagccata tcctgctttt tccatctcat ccttggccac aaagcgtaaa
     9181 gaagcagaat tgatacagta acggaggccg cctaactccc gcggtccatc tgtgaaaaca
     9241 tgacccaagt gagcactgcc tgaacgagaa cgaacttcaa ttcgctccat tccatggctc
     9301 agatccttgt aataatgaat caactctttg gaaatcggac ggctaaaact tggccaacca
     9361 caacctgaag caaacttatc cttggcaaaa aagagtggct cacctgtcgt aatatctaca
     9421 taaatcccct cttcaaaggt ttggtcatag gcattggtaa atggagcctc tgtagcagct
     9481 tcttgtgtga cacgataaga ctcttcagat agactggcct tcaacacctc ttgactaggc
     9541 ttttcatagt ttgctgcatc aatcaatggc ttatcagcat cggtcacatc gatatgacag
     9601 taacctgaag gattcttcct gagatagtct tggtggtagt cttcagccag aatgtagtgg
     9661 cgtaattgct ccacttctac tgcaatcttt cgacccagca tgcgttcctg ctcctgcacc
     9721 actgtgtaga tagctggcaa atctgcttca tcctgataat aaatcccagt tcgatattgg
     9781 cggccacggt cattcccttg ttgattgata gatagaggat cgataactcg gaaataataa
     9841 agtaaaatct ctctgagtga cacttccttc tcatcgtaaa tcacttggac cgtttctgca
     9901 tggtctgttt ccttgatcaa ctggtaattg gtcgtttcga cttgaccatt agcgtagcca
     9961 acactggttt ctagcactcc agaaatgcgt gaaaaatatt cctctaggcc ccaaaaacaa
    10021 ccacctgcta gataaatttc tgccatcttt atttctcctt tatcacgttt ttaactaata
    10081 ctcttcgaaa atctcttcaa accacgttag cgtcacctta ccgtatatat gttactgact
    10141 tcgtcagttc tatctgcaac ctcaaaacag tgtcttgagc tgacttcgtc agttctatct
    10201 gcaacctcaa aacactgttt tgagcagcct gcggctagct tcctagtttg ctctttgatt
    10261 ttcattgagt ataaacttct tttcacaaaa aggatatgaa accctctggt taagagtttc
    10321 cccatcctat cttctattct ttattttgct tctacacgga caccttgggt atcaactctc
    10381 aagtcatgca gttttccttt gaaaggttgc ttttccaatt ctgccttaat tgttggcatc
    10441 ttgtcatgag aagccagaac cataactgtc ggcccagcac cagaaaggta ggttgcatag
    10501 gccccatttt ctttggtcac ttgcttaatc atcgcaaatt ctcttaccaa gtcctgacga
    10561 taacgctcat ggaagaggtc tccctcgatt gcttgcccag cggtcaccat gtctcctgcc
    10621 aacaaggcag caaccgctac attggcgata gaacttgcag caacagcttc cttataagac
    10681 aattttttag gcaagacact acggctgtcg cgagtacgta attcatagtt tggaatgtaa
    10741 gctagaaaat cacactctgg aaagtctgct acgatagcag agacttgccc ttcaacagaa
    10801 cttgcaataa cgagattacc ataaatggct ggagccacat tgtcaggatg cccttcaatc
    10861 ttggtcgcta actgcaattt ttcatggtct gataagttga gttgacccag ttggttggct
    10921 agttcaatcc cagcaacgat aaccgagctg gaagaaccca aaccgcgcgc caaagggaca
    10981 tcactggtca ttttcaagcg tcttggttgc aagtctggta caatttgcaa agcgattttg
    11041 agcaagagat tacgctcatc atgtggaatc catttgccaa tctggtgttc aatcagccac
    11101 tcatctcgtt cttcgcagac ctcaatttga agatacttgg ttacagctac accgaccgag
    11161 tcaaaacctg gcccgatatt ggcactggtt gcaggtacaa taatcttcat cttattctcc
    11221 tagcaccttg aaggtattca agaggtcgaa ttctgaaacc ttcttcaatt cagctgagac
    11281 attttcaagc tgggctttat taatcttgtg tgtgatgata acgacacgcg ccttgtcacc
    11341 ctctttgcca tcttgaagga tttgcttaaa ggaaatatct tgagcattga agatttcagc
    11401 caacttcaag acctgacctt ttgagtctgg agccaagatt gagaaatagt agtttgcttt
    11461 gacatcttca ggatttgcca agaccaagtc acggctatat tcgttgaagt ctttgccaat
    11521 ggtaccatca ttcaaacgac gaacgatacg gacaatatca gctacaacac ttgttgcagt
    11581 tggtttttga cccgcacctg gtccgtagta catagactca ccaataccga tagattctac
    11641 aaagacagcg ttcattacgc cattcacact agcaagtggg tgcgctttag gtaggaaggt
    11701 tggagtcact tctgcagcaa tacctgaaga agtttcctca atagaaccaa ccaatttcac
    11761 tacgtaacca aactcttgag ctacagctac gtcttctggt gtgatattgc ggattccctt
    11821 gtgggctaca tcatcaaagg caatcttcat gccaaaggca aattggctca aaataaccat
    11881 cttgtaggct gcatcaatcc catctacgtc attcgtcgga tcgctttctg caaatcctag
    11941 acgttgtgct tccgcaagag catcatcgta agaccagcct tcttccacca tcttggtcac
    12001 catgaagttg gaagttccgt tgactactcc aagcacgcgc gtaattttat cagaagccaa
    12061 ggaatttgct aaagtacgaa gaattggaat cccaccagca actgctgctt cgtagtaaag
    12121 tgctaccttg ttagcttgag cgatttctag caattctgcg ccatggacag ctaaaaggtc
    12181 cttgttagca gtaacaacgt gttttccagc ttccaaggca cgagtgataa aggttttagc
    12241 aggctcaata cgccccatca attccactac gatagtaata tcctggtctg ataaaatatc
    12301 atccacattg gttacaaagt taaagtcatt ccctgctgca agcaagcgat ttttttcatc
    12361 ttcatccttg accaatacct tagcaacttt gatatctgaa tgtgctgatt gattgatttt
    12421 tcctccattt tcctttagga ggaaaggcac accacttgca acggtaccaa atcctagtaa
    12481 agcaatttta actgtcatct ttatctcctc gaaattttct aatatagcca ttataacaga
    12541 attttgtgaa aattcctatt atagtaaatc actatttcag tataaaaaga aaaaacgaat
    12601 cagacgattc gctcttctta aaatctgaaa atagctttcc agaaaggatt agccgatttt
    12661 ttgcagattg agcactgcat cgtgactcat caagacttga ccatactctt gtaagactga
    12721 gcgactgata tcactatcgt ctgcaaactc gcgcatacgg gccaacagcc aagctggata
    12781 tgggcttgga tgattttcaa tatccactaa aatggtcaaa taatagcgct cgttcatttt
    12841 gtagagttca gaagtttcca tttcaaaagt cactgtcttg gcaaaaacta ccaagtcagc
    12901 caacttagca aaagaaagga tgtagtagat gtaaggttct ttcttactct cagcttcttg
    12961 ttcagcctgc tcttgctctt cttccttggc ttcaacttgc tcaagagatt gaatggcttc
    13021 gatatcatcc ttggttttgt ctgcgatgct tttttccagg gttttgataa attcatctgg
    13081 agacatttga gccaattctt ccatatctgg caaatccgat aagtcttcaa aatctagatt
    13141 ttggtcaatc tttgacttgg tcacaaagac atctacctta tcaggttttg gagtcacacg
    13201 gaagctcaac atgcctgtat ccagaaagct atcaggcatc tctagttcat ccaagatagc
    13261 ataaaagaac tcttctgttt tttcttgagg aacgagaaag tcagcaatct ccattccacg
    13321 atccatcaaa tcctctaaag acatcgtgat ttttaaagtt gtatcactaa tttgtttcat
    13381 tttcattgct agtaacctca tactttcagt tctatctatt atactagatt tttacgattt
    13441 tatcaaaaga aggctcctct atacggatag attttcccta gggtctttct ataggagact
    13501 ccaaaagaaa atttctgcag acagatagaa aaagccttca aaatcagctc ttagccgatt
    13561 ttgaagacct tatacatcag aatacttata atttaaaggt tgctacacca aggatagaac
    13621 gatttaagtt tctgagaatt tgaagacttt gctcaaattt cttataacga gtcactccgt
    13681 actcttcaac aagaaggact gtatctcttt ccaaaagaga tgatacatcc tgtaaatcta
    13741 caaaatgcat tccttttaaa gcttcttgac tctgtttcaa tttatctagg atagctttat
    13801 ttgagctaac gatggtcaat tcctgtccag tatttttgta tgacaaaaca tctgctaggt
    13861 tagcaattgt tgtaatctct gttacaaaat caatttgata ctgagaaaaa tcacctactc
    13921 tattgattgt tggattaaag agataaacta acacatttcc catcacaacc aaaatcacac
    13981 aaaccactcc aataacaact aaacgaagaa tcagattttt cacatttaag ccaagcgctg
    14041 tttcaccatt tgcgttcaat tctttagagt tgatggtttc cagtttttca attttcacat
    14101 ttgcataggc atgtttaaat ttctcaatca acccatcaat ttttttctct aacaagtcat
    14161 tggcatcttt acttgatgtc aaaattttca caccaacccc tgcatcgtca atcatatagt
    14221 agacggtcaa ttttttccac caatagtcat tcgttgaatt tttcaaggtt gtttctgtcg
    14281 tgtctaattc actggcaatt tttttcaact cactgggttc tacatcattg aaaagataag
    14341 ctccattcaa attaccatca atcaatttcc cataaaaatc actataacca ccaatttgat
    14401 gattcaaaat cgttttggcc gactcttttg gaggagtgat tttatagata agataagttg
    14461 aataacttgt tgtatctttg acagtgtttt tattcctaac tgctttaatt gtaaatggta
    14521 cagcaatgag agcaaataaa gcgatgagag ctaaaatatt tgcttttcgc tttttataaa
    14581 gatttgcaaa caaatcagct actgaataat gttcaaacat gatttttttc tcctttgttt
    14641 agtagatact agttttcctt tgtaagcatt tttgctacaa atataatcac aagaacaatt
    14701 ccccagaatt gcattgtaaa taaattgaag aaactttctg aaaagctgct tcttggcata
    14761 aagaatagat tattcaagat gagtagggat aaagcaaata ggattgtcct tgagcgatag
    14821 gctacttgca gcatggctat aaataatacg ccgagtaaga aactaagcag aaagactcca
    14881 atcataccat agtcggtata caactccatg atataactac ttccgatacc atgccctttc
    14941 aagtattcct tgttcaagac aagataggat agattgtggg cataactatt actatcaata
    15001 gctagttcca cactattggt tgtatgttca aaggcttttc ctccgaaaat ggctcccaaa
    15061 ctcccccttg caaaataatc aagaacagga ccaaaagtaa aattacggaa atctcggtaa
    15121 gggaggctac tgttaaatag aaaacctcga gccagaacac caaaactagt cccttgttta
    15181 tagataaagt caagtaagat atcccagaaa cctgtatgag aaacttggac attatcccgt
    15241 acataattga gtactcccat cgctaacatg agaataggag aacctacaaa aatcgctaac
    15301 ttttctttaa acccaatcca ttttcctttt tcagtttgct cccgcataaa gtaataaaca
    15361 aaagcaaata aaatacttaa aataaaggga tttcgtgtcc caattgccaa atgaatagta
    15421 ttagctgcaa taaaggagac aagcactgct gtggcctgca atttctttgg cttggttgcc
    15481 agatacatac acattgcata gaccgtaaag gtagacaaaa tgtaggtaaa ataaggcagt
    15541 ttactttcaa aatttgcata gtaggcatag taggaagtct gcaaacgata caagagccgt
    15601 tcaaataacc gaatgaaata gaaaggatag gttagaagaa aaactcctag tgatacaaag
    15661 cgtaaccgct tgatataaac ctcttttaga gaatttccta tatttgctac ttttattttc
    15721 ttcctagcta tgaagtaacg agccagaatg cctcctgtgg tcaagcccag aatcgaaacc
    15781 atgacaacta taaaggcaaa acgataggct attggatgat aggtatccaa agcaccatcc
    15841 ctaaaataat caatggtcgg tcttgatacc agaaatacaa aaatggttaa atagaaaata
    15901 aaatggatta agtaatactt gatatcattc caacaagcaa ttaagctact aaccaacaag
    15961 aacaataaag tagaaagtaa gctaacatta ttattattaa acagatacac aattccactt
    16021 actagcgtca aggcataact gactatggtc aaactaaata ataatcgttt cccatcaatc
    16081 acttggtcac ccccgttcta atgtaatttt ttagattttt caatattttt cagtaataag
    16141 aatcgatata aggaaatatt tatgaatagg gccaaagcac taattcttct ccccttacgg
    16201 aaaattggat tcctagaaat agcaaaggca tggcctttta aaaaacgatg aatctgagaa
    16261 taggcttcaa actgtttata ctgatcatct agcaacatct tatccagaat aaagaagtgg
    16321 gcataggcca atctgaaaaa agcgacctct ttcaagtcag gatagttttt cacaacttca
    16381 ttataaaact tttggtagat atcaatatag gctaaatcct tctctgcata gggtttggtc
    16441 gtaatactat cccctctatg gaaatagtaa taatagggtt tagtattaac cacatacttc
    16501 ttggccaact tgattaaatc aaaatggtaa taggcatctt cgtaaatcaa ccccttagga
    16561 aaggataggg cagttgcaat ctgtctcttg attagcttat tgcaaatcgt cccaggtatt
    16621 ttttcaccta tgaggtattc ctttagaaat gtttgagaat cacagacaaa atagtcatcc
    16681 tgattggctg actgtgggct ttcatcatta gcatagacat tcatgacacc acagcttgaa
    16741 acatccgcat cttcttgaac taattgctca tataagctct gaatcatttc tggatggata
    16801 taatcatctg agtcaataaa aatcagataa tccccgtgag cctgcttcat cccatcattt
    16861 cgtgcttgcg acaatccttc gttcttttta tgaagcactg acaccctgtc atcttgttca
    16921 gcgattgaat cacacaagcg accactttca tctgttgcac catcatcaac aagaataatt
    16981 tccagatttt gataggtctg cttctgaatg gaagctatcg atttttctag gtactgcgcc
    17041 acattataga ctggcacaat cacactaatt aatgcagttt ccatgctact cctctaatag
    17101 tttttctact tgttcgattt gttttgtaat tgtaaattgt tgaatgaatt ggctagcctc
    17161 atcgacatca aagtttgagg cagaagtcat gtaattagta atcgcctgag ctgcctcttg
    17221 attgctctca atgatttgtc caaatcgtcc ttcttgggat aattcctcag cccctccaac
    17281 gttcgtagag ataaaaggga gtcccagact caaggcctcc acatacactc caggaaaacc
    17341 ttcttgttta gacatagaca aaagaacttt cgtctgagat agatactgat aaggattttt
    17401 ttgataacca aggaaatgta catagtcctc aatcccatac tctttgactc gttttttcag
    17461 ttcctcttcc atatcaccag ccccgataaa atagagatga tagttttttc cctcttggtg
    17521 taataatcgt atcacttcca ctacacggtc agaaccctta ttttcctcaa tccgtccgat
    17581 agtacagata ctttgaggag caatctcgat atcgatcttc tcttgagatt tttctagaat
    17641 agtctgaaaa tcatatccat tgtagattgt ctgtaattta gaagtataat ctggataaac
    17701 ttccttgata gaattgctgg tcttttttga aatccctaca attgtattcg cagcatccaa
    17761 ctggcttcta tgtgattctc ttttagagct atccttaaga agttcttcaa tacttccatg
    17821 aatccaagat atcttcttga cttctcttct tttagagaac aacagtggtg gattcataat
    17881 ggtaaaagaa acttcaacat cataatcatc ttttacaagc aaacgacgag ccagtcttgg
    17941 aaaataaatt ctcattctcc acaaaaaagc tcgtaaccat ctggtttggc gataatcttg
    18001 aagggatttt aaaatgcgta catgctttgg aacagattca tatcccttgt caaagtgctc
    18061 catttcaaga atatcaatat catacttttc tggatccaga tttgaaacaa tggttgatag
    18121 aatcttctct gcaccacctc caagagaaaa agaccacata aaaaataaga tttttttctt
    18181 agccaccata ttctcccttg tattctgtat aagacttatc catatcagcg atgacagcat
    18241 catgatgcgg tacctgcttg tctgctggtg gaggcgtcat ataatcccca aaagcagttc
    18301 tgagatagac atcatagccg attggaatag gcatctctgt tccttcaaat ggcaagaaaa
    18361 gattgtcttc aaaagatgtg attgggtact tgtttctcat gtagccagga cctgagcata
    18421 attctgtaat gccatcacaa tcagccaaat catacttagt catttctttc tcagcttttt
    18481 tccagatgcg ataacagaga gattttggag tcaaacccag taaaatgcga cttccccatt
    18541 tcatgagagc accatgcttt tctggaatag tttgcgcaca aaagagtgaa taaatcaagg
    18601 cccaacgaac ctgttttttc cgctcagctg gatttttcgg ataataatcc aaaggcaaaa
    18661 catccaaggc cagaccatgt ggcaaatcca aatcctgctg ataaggcttg atacaggtgg
    18721 tttccttgtc acgaatggta ataaaaagat tacgatcaac aaaatccttg tgactctttg
    18781 acaagaaata acgttcatct gcataacgag gccataattc tgctaatttc tcataatctt
    18841 tacgaggcat aaaaaagtct aggtcgtcgt cccaaggaat aaatcccttg tttcgaaggg
    18901 caccaatagc gcctccgcca cagagataac agagcaaatc atgttcttta caaaaggcca
    18961 caaaatattc agccatctcc agactacgag cctgaattgc ttttaaatca gtcatattgt
    19021 tcattattct ttctatcgta tcgtttcatt ataccacaaa caaggggtga aaatctattg
    19081 cagactgtaa aaaatcaaag cctgactgct atccaaatag ctatcaaact ttgatttttc
    19141 tgtcttatac tcttcgaaaa tctcttcaaa ccacgtcagc ttcaccttgc cgtaggtata
    19201 ggtaactgac ttcgtcagtc ttatctacaa cctcaaaact gtgtttttag cagcctgcgg
    19261 ctagcttcct agtttgcact ttgattttca ttgagtatta tcttatctca agcccatttg
    19321 agcgagcttg gtttgatatt tgttttgatc aaccagcaag cccaagcctc cataaacatc
    19381 ataggcatct acccagtcac ccagttctgg aatcgtcaat ttttcaatac cattttttgc
    19441 tccatccaaa acagataaac cgtttgttag gaggaaagta tagggtacgt tggttgaggt
    19501 catagcaaaa acctttccaa gagcttcaga accagtgaaa agtttagtgg gatctttaat
    19561 ttgctctaaa attgctgtta aaacttgttg ctgtcttttt gtacggccgt aatccgcctc
    19621 atcatcacgg aaacgagcat aattgagcag ggtcgagcca ttcatctgct gttttccgac
    19681 tttaatggtt tgggttggag actcagtctc ggtagcgtat aaatcatctc cgactgtagc
    19741 ttctgttagg ggacgcccat tcaatgttga aaattgagca tcaatcgtca ccccatcagg
    19801 gaaaagcgtg tcaatcgctg tggcaaaggc ctggaaatca accaaggcgt agtacttaat
    19861 gtccaagtca aaattatctt tcaagacttg gcgaaccatt tctgcccctt tttgcccctc
    19921 ttgttctcct aactcgtagg ctacgtttaa cttgttatct gtctgttttc taccgttaat
    19981 cacttgacta taaccatcta tatagaccaa attatcacgc atgaaactga ctagcttcat
    20041 tttcttatct gagcccccga catttaatac cataatagag tcagttcgtg tctcaacact
    20101 gttctggccg attcgaccat cagtacccat gattaaaata ttaactccat ctctagtgtc
    20161 ctgaccatta aagacttcta cttgagctgc ccgggcatca gcagttttct ttgcgctagc
    20221 atcttggtaa ccacgcaaaa acatgaatac catggccaaa gccacacaga ccaaaagtga
    20281 aaaaatcacc ataaaaattc gtttaagacg gagcttccgt cttttctttt ttggagggaa
    20341 agagagtgct tgtgatttgg attgtgagcg actccggttc gcatagcttg gtaagtcaac
    20401 ctgctcttct ctttcttgtt ccaagctaga gctactattt cccctagcaa gagttagctt
    20461 ttcttgcaaa taggcaaact catttttttc tctctcattg agatagtgaa tattttttag
    20521 caaataatca taacgcaact gctcatgatg acttaaggga ttttctttac tcatcttctc
    20581 tcctttccat ggtctgatat tggataaata ggataggcac ccagaatttt atactggatt
    20641 ccaatcgctt ctaattcttt ttgggcaaag tggaccaagt ccttatcggt ataatccaca
    20701 tcgataatga aaaagtattc acccagtgct gtcttgagtg gacgactttc aatttttgtc
    20761 aagtcaattc ctcgccaagc aaaggtcgac agggccttat aaagtgcacc tggaaggttg
    20821 tcaggtaatg tcaaggccaa actcatcttt tcagtttgtg cttgcaaggg aatactaggc
    20881 ttttcagctc ctagaaccca gaaacgtgtg aaattggctt ccatttcctg aatatcctcg
    20941 gcaatcagtt ccaatccata ttcttcagca gaacttctag gtgcaactgc tgcaaagggc
    21001 tggtctggat gttcggaaat aaaacgggcc gcataagctg tactagctgt tacctcgatt
    21061 tgagcctctg gatattgttc atcgatgaat ttctttcctt gagccaaggc ctgtggatgt
    21121 gaaaaaatct tttcaatctt agtatggcct ggaaccacca tcaactgctg atgaataggc
    21181 tgaacgattt ctgctactgc ttggatgtga gcctgatgaa aaagatagtc caaggtttca
    21241 tgaacactac cctcaataga attttcaact ggcaccacag aatagtccac taatccttgc
    21301 tcataagcct tgatgacatc tgtaatgtta gcaaaagcct gcaattcctc atgaggaaaa
    21361 gctatctgca caacgtggtg tgaaaatgat cccttgggac ctagataagc aattttcatc
    21421 ttagttcctc tataatttcc tctgggctta gcttggtcac atccaaaacc cgactagcca
    21481 cttcctcata ccaagcctgt ctttcttgaa aaatagctac tagttcttcc ttgctattat
    21541 ttagaaaaag cggtcgctga ttgtccttat cagctgcgat acgttggtag agggtttcaa
    21601 aatctgcttt caggtagatg ttatctgtat tagtcttgag taagtcacga tttctctgag
    21661 aaataaccac tcctcctcca gttgacacga cttggtctgt ttgtagtaaa tcagctagga
    21721 cttctgattc tacctgacga aaggctgctt ctcccttttc agcgaaaaaa ttcgcaatgg
    21781 acatacctag gcgcttctca atcagagcat ccatatcaag gtaattaggg tccaagcctc
    21841 ttgcaatagt cgattttcca gcccccataa accctaataa caccttagcc atgaatcaag
    21901 ctctccaaat catcaaagaa actaggatag ctggtattga tggcttctgc acggtcaagc
    21961 tccacctctc catctgcaac caagagggct gcgatagctg tcatcatgcc gatacggtgg
    22021 tcaccaaacg tattgactct agcaccgtga agagctgatt tccctttgat aatcatccca
    22081 tctgccgtag gagtaatatc tgctcccata ctatttaagg cgtctgccac aacctgaata
    22141 cggtctgttt ccttgacctt gagctcctca gcatccttga taactgttac accttgggct
    22201 tgagtcgcaa gcagggcaat aatgggcaat tcatcaatca atcgtggaat caaagcgcca
    22261 ccaatctctg ttcctttcaa gtcagaagac tcaacagtca aggtagaaga tttagcgact
    22321 ggatcgattt cagttatttc caattttcca cccatggcac gaatgacatc aataataccg
    22381 gtgcgagttt cgttgatccc cacattctgc agcactagac gagaatttgg aacaatcaaa
    22441 cctgcgacta accaaaaggc tgcactggaa atatctcctg gtacgaccac cttctgtcct
    22501 gtcaattttt gtggcccttg gactgtgatt ttcttaccgt ccacacttaa atgaccacca
    22561 aattgtttca acatatcttc agtatgatta cgggtgcact ctttttcgat aataactgac
    22621 tcccccttag cttgtaaggc tgcaaacatc aaggctgact tgacttgggc agaggcaatt
    22681 ggcaactcat aatgaatagg tcttaggttt ttcgtccctt ttaagcgaag gggaggcaag
    22741 tctcgttcag tttgccctga aatgctgacg cccatttttt tcagtggaag ggtcacacgg
    22801 tccataggac gtttggaaag actatcatct ccaaacatct ctacttcgaa atctgcacca
    22861 gcaaggacac ctgaaatcag gcgaatcgag gtgccagaat ttcccatatt aagggcattt
    22921 tgtggcgctt ttaagccagc catgcctaca ccttgaatgg taataacccc atctttatcc
    22981 tcaatttcaa caccaaggtc acgaaaaacc tgcatggtcg aaagaacgtc ttcacctcgc
    23041 agaatatcat aaaccttggt ctcaccctca gccaaacttc caaagataat ggaacggtgg
    23101 ctgatagact tgtcacctgg gacgcggata ctaccatgta aatggcgaat gtttgttttt
    23161 agtttcatac tggacctcat acttgcaata cttttaccta ttttatcata aaaagccaga
    23221 aattccttaa aaattcctga ctttaggatc gttcttttct tatttcagca attctgaaac
    23281 tggttcaaaa acaatttttt caatgtcaga aaggtaaatg gccaattgtt gttgcttggt
    23341 aaagaattct gacaagaggc tatttccttg aatctgttta ccaaagcctt ccatcttagc
    23401 ttggaaggac gcatctggca tttgacctgt atgtgctagt ttttgaattt cctcttgaaa
    23461 ggcaagatat tctgtaaaga ttttgcttgc ctcagcatct gctgcaatcg catctttagc
    23521 tgctttaaca gccttgtatt ctggtaatcc gcgtagaccg cgactgagtt cgtttgcact
    23581 atcgtaaata tttgacatgt tcttctcctt atttgatgac gactgtatag tcggtatttt
    23641 ctgttatgag atgctcagct ctttccaagt cttgagcatt tttaaatgaa atttgtagga
    23701 ttccgtgaat atcctcacga ttttcctcgt tgatgtggat gttaaccaag gaagtcccac
    23761 gtagcagttc caaaatccgc aggatgacat cttcttcatc aggaacgtca acatagaggt
    23821 cgtaagagct atccacacca ccacgcttat ggatttccat ggtctggcgt tgttcacgcg
    23881 cttggttaaa aaagttccaa atttgctctt catctccctt actaatggcc tgaccaatca
    23941 cttccaaacg ttccttgaaa tcctcaattc tatccagaat ggtctcgcta ttggacaaga
    24001 gaatggaggt ccacattcct ggctcgcttt ccgcaattcg ggtcatatct cgaaaaccac
    24061 ctgccgcaaa gcgccttgcc atctcatgct cttgagcata gaccgcagtc tgctccatga
    24121 gactagaagc caaaatatga ggaaaatggc taatctgaga agtgacacga tcatgctcct
    24181 tggcatcaat ctcgataaaa cgagcatgaa gacctgaaag cagatccttc atttccttaa
    24241 gcgtgtcctg acttgtcagg cttgaaggtg taaagatata ataggcattt tcaaaaagat
    24301 tgacatctgc cgaagcagcc cctgtcttgt gactaccagc catgggatgg gccccgacaa
    24361 agcgaacaga cttgccagcc aaatactgct ccgccgcatc cacaatggtt gacttggtcg
    24421 aaccagcatc tgaaataata acgccttctc gcaaatccaa attggccaac tccttaatga
    24481 aagcaatagt ttgtttgatt ggcaagctga ggataatgac atctgccaaa ggagcaaaac
    24541 tagcaaaatc atccgttgca cggtcaatca tgccttcttt caaggcgata tctctcgaag
    24601 cttgactacg attataacct aaaatttcat aatctggatg atcgcgtttg ataccaagtg
    24661 ccatagaggc tccaatcaac ccaagacctg cgatatagat tgtttttgcc ataggaactc
    24721 cttaatagtt ctttgtatag tctcggtgtt tggctaccgc ttcttttagt tcctcaagat
    24781 tatctgatga gaatttttcg aggatttctt gcgccagaac cgttgctaca actgcttcca
    24841 tgaccattcc tgcagctgga agagcagtcg gatcacttct ctccacggtt gccttgtaag
    24901 gttcgtgggt ttcgatatcc acactcataa gaggtttata aagagtagga atgggtttca
    24961 tgaccccacg aacaacgatg ggttgcccat tagtcatacc accttcaaaa ccacctagat
    25021 tattggtacg gcgagtataa ccgtcttctt tagaccagag aatttcatcc ataacttggc
    25081 tgcctttacg ataaccagcc tcaaagccaa gaccaaattc caccccttta aaggcattga
    25141 tagagacaac agcttgagcc aatcttgcat ccaattttct atcccattgg acataggaac
    25201 caagaccaac tggaacgcct ccgacgactg tctccacaac cccaccgatg gtatcaccat
    25261 cacgtttgat ttggtcaata tagtccttga tttcctgttc tcgttcttgg ttaacaatag
    25321 aaacttcaga ctgggcagct ctttgcttaa tttcagcgac tgtcagattt tcaggaacat
    25381 cgatttcctt gccaccaaag accacgacat ggttggcaat ctccatatcc agctcagcca
    25441 agaggcgttt ggctactgca ccaactgcca cccgcatggt ggtttcacga gctgatgaac
    25501 gctccaaaga atttcgcaaa tcatcaaaac ggtacttaat ccccccaacc aaatcggcat
    25561 gacctgggcg aggatgagta attttccgct tgcttttaag gcggtcttca atgtcctccg
    25621 cagacatgat gtccagccat ttctggtggt ccttattgat gacatccata gtaataggcg
    25681 cccctgtcgt cttcccgtgg cgaacgcccg aagtaaagac aacctggtca ctctcaatct
    25741 tcatacgacc accacgaccg tagccaccct gacggcgtct aaggtcctca ttgatatcct
    25801 cagctgtcaa tggaagtcca gctggaattc cctcaataat agctgttaga cgggggccgt
    25861 gtgattctcc tgcagttaaa tatctcatac actctcctta ttttaccaag tagtctttca
    25921 tctcttccag agaaactggg tgaatgatcg ctgaaccaag ctctgacacc aagaccaatt
    25981 tcaaggtgtt accacgcgtt ttcttgtcat gagtaagagc ctgataaagc ttgtcaactt
    26041 cccaattttc atagtcaaca ggcaagccga atttctgaca catctctgtg atagattggg
    26101 taatgccagc tggcatgagg cctttttcct cagcaacctt ggaaatctgt accattccca
    26161 tggcaacagc ctctccatgc atgaccttgc cataaccggc agtcgcttcg atggcatggc
    26221 caatagtgtg gccaaaattg aggtaaagac gaataccatt gtccaactca tcttcaacca
    26281 ccatcttgcg cttcacctga caagaatgtt caatcaaggt ctctgcatgt tccaaaatgc
    26341 tctcaacaga accattcagt tccgtcaaga gagcccacag ttctggatcc tcaatcaagc
    26401 catacttgat aacttcaccc atcccttcaa tcaactctct ttttccgagg gtttcaagaa
    26461 caagtggatc aatcagaacc ccatctggtt gggcaaaggt ccccaccata tttttagcaa
    26521 atggtgtgtt aacgcctgtc tttccaccga tagaagaatc aacctgagct gtcaaactag
    26581 tcggaatctg aacaaagtga ataccccgca tataggtaga ggctacaaat ccagccaggt
    26641 ccccaacaac gccaccacca agagcaacga ttccatcgct acgagtcaga ccttgcttga
    26701 ctagaaattc atagactttc tgaacagtag ttaaattctt tctttcttca ccttctaaga
    26761 aatcaaaaac agctacctga aaaccagcat cttctaggct gagcttgacc ttctctgcat
    26821 agagagaggc tacatggtta tctgtcacaa tgactacctt ttgcggttgc cagagttctc
    26881 gcaaccactg accagcctgg gccatacaac ctttttcaat ctgaatatca taaggatgat
    26941 gaggaatatc gattctgatt ttcataggag agtctccctt tctttattgg tatttttctg
    27001 ttaaagactg ccaaatctct tctgtcggca tttccttgcc tgtccacagt tgaaaagctt
    27061 ctgcagcttg atagagcaac attcccagac cattgactgc tggattgccc tgacttctag
    27121 cccatttcaa aaacggtgtt tcaaagggtt ggtatatgat atctgcaact aagagagttt
    27181 ctggtaagac tatgttttca ggaacaggag aggattggcc atccatgccc acactggtgg
    27241 cattaactag caaatccgac tcggcaatcc ttgcttgcag ttcagaaaca ttctctaaag
    27301 cacacaaatc cactttaaaa cctgtctgct cctgtaactt gtctaggtaa ggtcttgttt
    27361 tttccataga aacggaacga acaaagaccg aaatctgact gacgccatcc aaaatagcct
    27421 gtgccaagat tgatttagcc gcaccacctg cacccagcag ggtcatcttt ttacctgaaa
    27481 ttgtaaaaga aggcaagcac ttaaaaaatc ccttgccatc tgtattatat ccaattaaat
    27541 tgccattctc attgacaacc gtattaaccg caccaatcaa gcgcgcttca tcgctcagct
    27601 tatccaaata aggaatcacc tgctccttat agggcatgga cagattgatg ccaaacatct
    27661 ggtagcgacg aatattggcc actgtttctg ccaagtcact cgcttcaatc tcccaagcca
    27721 cataagcacc gttggtagct gtcgcctcaa aggctctatt gtggatgaag ggagaaatag
    27781 aatgcttaat aggattggca acaactgcag ctaaacgtgt atagccatca agcttcatcc
    27841 aaaatctccc tgattttttt catgctagct agagaaatct gcccaggggc actaacctca
    27901 tccagactgg caaaagacca actcgaacca gtcacatccg cagtgatacg agagaccttg
    27961 cccaccttac ccatagaaat ggtcacatat tcctgttcag gattgagggt tttaaagcct
    28021 cgtgtatagt tcatcaagtc taagacatcc tgctccgtgt gagccatcac cgcaacctta
    28081 acaagttttg gatttaggat cgtcaactct gacaagattt ccatcatgtt ctcaggtgtt
    28141 tcttggaaat tatggtaact caaaacaaga tttgggaagt ccagcatttc ctcaaaaaca
    28201 tccttgtagc tatagtactc aaaatcaata tagtctggtt gatagaattg cgcaacttcc
    28261 ttgattagat ggatatactc ttctggagaa aggtcgattt ctccaccttc ggagcgagtt
    28321 cgtagcgtga aaaccaactc acggcctgcg aatttttcaa aaatggctgg agctacctgc
    28381 aaaatcgctt ctttaggcag atagtcggca cgccattcaa tgatgtcggc atccaggtac
    28441 ctcgtggcat ccagagcctg agcctcctct aaacttcttg gcattactga aacgattaat
    28501 ttcatttact aaccttcata ctaatcacct tgaggtaatt actactttca tcttttttat
    28561 tataggcaaa atctgctgga agaccatatt tgtttaaaat ctggtaactt cttcctgcaa
    28621 agcctttatc aatttgttct gtaaatttct gacgggaaac attggcagca ttggtactgg
    28681 caatgataat ccctcccgga tttaaaatct caagactctg ggaaatcaac ttgtgataat
    28741 ccttggccac agagaaagtt tgttttttat tccgagcaaa gctaggcgga tctaggacaa
    28801 tcacatcgta ggtcaagtct ttgcgtttgg catatttgaa atactcaaag acatccatga
    28861 ctataaaacg atgctcgtct gtgctgagcc catttgcctg aaaatgcgct tgagacaatt
    28921 ctcgtgaacg tttggctaga tcaacagaag ttgtctggct agctcctccc atggccgcag
    28981 ctactgaaaa agccgctgtg taggaaaaca tattgagcaa ggatttaccc atagccaagc
    29041 cgtcaactaa actaccgcga acctcatgct ggtctaggaa aattcctgtc atcaagccat
    29101 cattcataaa gacttgatac aggacaccat tttctaaaac agtgaaaaag tcaggtgctt
    29161 cttgaccata aacatgggca gattcatagt caaaaccctt aaagcggatt ttctcataag
    29221 cccctaaaac ctcagggaaa acctgtctaa aggcttctga tatagtctga cgaatctgat
    29281 aaacataaga gttataccaa gaaaagacgg cgtagtcgcc ataaaggtcc actgtcagac
    29341 ccccaaagcc atctccctct tgattaaaga gacgaaaggc agttgtcaaa tcatcttgat
    29401 agtaggcgtt tctcttttct ttggcttttc taaacaacgt ttcaaagaaa gtttgattga
    29461 aggccacctt gtctttgctg acaaaccagc ccaagccctt gttttgctga gaaaggtagg
    29521 cagtcccaag aaagtttcct tcctgaccct gcacctctac ttcctgatcc ttaagattga
    29581 cattctcaag atcactggct tctagtaaaa ctagcccctt agcaagcttc ttttcaaccc
    29641 ttttgctgac tcttattcta ttcataacta ccattatatc aaacttttag acaattctca
    29701 aaaaagaaac tacccttgct tttttactct tcttttaaaa aatggtatac tagacttcct
    29761 gcaaaactag gaaataaatg tgtaagaatc acaataaaaa atgctcttcc gtcttggagg
    29821 agcatttctt tttatcaacg aaaatcaaat agcaaactat gaaactagcc tcaggttaac
    29881 cgtgagatta taggtagaga ggttgtatca gcaatatgtg tctgtcaaat ttagtgacaa
    29941 aggtagtaga agaaagatga agaaataaat cagcttcagt aggtatctgg aaaatttgat
    30001 tttatagaga agccttttgt tacaaactca atatactatc aataaataat attatagaag
    30061 caacaataat taaaatttca cctatttgca tcattctatt tcgaactcta aatatatgtt
    30121 ctatcaaaaa tacttggatc acacacatta taggaattaa cgtttttgaa attgaaaaat
    30181 atcccaataa ataaactata aacaacaata atagaactat attatatttc ttattcaaaa
    30241 cattcctccc tatatttttg attaccaatc ttaatcattt acaactacat tctaacaaac
    30301 tataaaagcg tttgtcgaat tgaatttatc aagcaagcaa ccaactatct catctttttt
    30361 ctatttctgc caatatgcgt gacaggtaat aatgatagcc aaaaatagca agagcaagca
    30421 agacgataag agctcctact cccaagttga tggcaaggat aggggagaga gactgaacca
    30481 agaatatgct cccaattaca agggccatca ggattgcact ataaataaac aataaaacta
    30541 tggcgactat gccatttgaa cgattcacca ggtccgtaat gctactccaa ttggttgaca
    30601 gatttttaac gtccttaaag taatggtggc aagaaaggat gacactggca atgatccaga
    30661 ctacaagaag gtaaatcatc gaaaggatgg acaagcctag atatagagaa agaccgagca
    30721 aagtcagaac tggtaaaaag gactgaacag caaagataat ccaaaatttc actttcacat
    30781 aacgagcaaa gtcaaagggt aaactcttca gaaaatcaac attttccctc tccaaggaca
    30841 aggcaattga atgcaggctg gtgatattgt tattgacaac tgctataaac actcctacaa
    30901 aaaacaaggg taaccagtat ggaggatgaa tgtctggaac tatctgagaa tctcggattt
    30961 tggaaatcag actgatcatc atgagataag gaaggaaagc acttgtaaaa agcactgtaa
    31021 tcacaccagt cccctgtccc aagagggtga ggtggtagcg taaaaccata cggaaaaagc
    31081 cctttttagt agttgaaatc ctctccttgc tgcgacgttc ttttttgacc ttctcctcac
    31141 tgttaagcag gatcacgtca taaaaacgag gaaggacctt ctttttggtc agataaagca
    31201 ggaagagagt tagtcctatc caagcgagca gacccactaa ggcttctgtc gaaaaaggct
    31261 ccactgctat tttgtaaaag atatgaagag gataaaggag aaatggaatg tctctaactt
    31321 tgtcaacaat acttccaaaa gtcgactgaa gaaagaagat aaatattaaa ggtatgagaa
    31381 ctcctatccc aatcatcaca ttcgaaaaaa tagactgata ctttctgaag accctagtct
    31441 gagccaagaa atgtactgcc actaccgtca ctaaagtaac agagacaaat aataaggtca
    31501 aggacagtag catcaaaggc aaacccagcc aaagagaagg agctagacta atatagaggg
    31561 ctagaaaata agctaggatt ggtacaattc cagttagagc tggcaagagg acagacagac
    31621 ctttggccat tataatctct gattctttaa aggcataggg cctataggag gccaggtcct
    31681 tactctcata aaagacattg taaaaggcag tgaaagaagt tgaaaaggcc agcaccagta
    31741 aaatagcaac catcgagcta aaataaatag gcatttcctc aaaaggaaaa tgaatggcta
    31801 tattactaaa acagatgagc atcaagagac tggaaaaaat gtaagaactt aggactctag
    31861 cagaaacatt tacttttttc ccaggattct tagcctgctt ctttcgtaga ttagccagat
    31921 tagcttcttg agatgaatag aggatattga tatcaactaa ttttttaatg accttgagac
    31981 gcatccgcaa cctcctcttt tctaccagca agactaaggt agatactttc caaaaactgg
    32041 tctgggtggt ctttcctcaa gtcctctacc ttaccacaat aaatcaaatg cccctttttc
    32101 aaaatggcaa tccgatcaca gacttgctct gccacctcta ggacatgagt tgaaaacaag
    32161 actgtcttcc ctttttgtgc atgttccttc atcatctgtt tcaaatcaaa ggcagcctgg
    32221 ggatccaaac cagtcaaggg ttcatccaag acccaaatat cgggatcaga caagagtgct
    32281 ccgatgacaa agactttctg acgcattccg tgagaaagag tttcaataac ctgatagcga
    32341 ttttcagcaa aatcaaaaac gttcaatagc ctagctagac tagcctccaa gtcagatcta
    32401 ctcagatcat aggatgaggc gatcaattcc caaaattcat tggccgttaa gcgtaaaaat
    32461 aagtcaggcg agtctgctac gtagccaatc tttcgtttaa tagccaagcg attttccgat
    32521 aactcctgac cgtctaccaa aatacgacca ctgctgggtg aaatgatact gactagggat
    32581 tttatggtgg tcgattttcc agccccatta tgaccaatca agcccataat ctctccattt
    32641 tcaatctgca aattgagatt actcaaggcc tctttatcac catacaactt actaacattt
    32701 tgaaattcaa tcatgggaca actcctatct ttatctgtat tatacatcgc tatactagca
    32761 ctttgataca aaaaaatcaa tactttattt taagtagtta aaatagtttc cttctatctt
    32821 acgcaaacgt ttgcaccaag agatacttta tgatagaata aagaacaaga ttgacaagta
    32881 agaggaaaca tcatgcaaaa tcaaacactc atgcaatact ttgaatggta tctgccccac
    32941 gacggtcaac actggacgcg tctggctgaa aatgctccac acctagctca tctggggatc
    33001 agtcacgtct ggatgccacc agccttcaag gcaaccaacg aaaaagatgt cggctatggg
    33061 gtctatgact tatttgactt aggagagttc aaccaaaaag ggactgtccg caccaagtat
    33121 ggtttcaaag aagactatct tcaagccatt caagccctta aagcacaggg aattcaacct
    33181 atggccgatg tagttctcaa ccacaaggct gctgccgatc acagggaagc ctttcaggtc
    33241 atcgaagttg atcctgtaga ccgtacagtt gaacttggag aacccttcac catcaatggc
    33301 tggactagtt ttaccttcga tggtcgccaa gatacctata atggcttcca ctggcattgg
    33361 taccacttca ccggtacaga ctacgatgcc aaacgcagta aatctgggat ttatctgatc
    33421 caaggggaca acaagggctg ggctaacgag gaattggtcg ataacgaaaa cggaaactac
    33481 gactacctca tgtatgccga cctagacttt aaacatcctg aagtcatcca aaacatctat
    33541 gactgggctg attggttcat ggaaacgact ggtgtagctg gtttccgttt ggatgccgtt
    33601 aagcatattg actctttctt tatgcgcaac ttcatccgcg atatgaagga aaaatacggt
    33661 gacgatttct atgtttttgg tgaattttgg aacccagaca aggaagccaa tctggactat
    33721 ctcgaaaaaa cggaagaaca ctttgacctt gtcgatgttc gtctccacca gaatctcttt
    33781 gaagccagtc aagctggcgc aaactatgac cttcgtggca ttttcacaga tagcctggtt
    33841 gaactcaagc ctgacaaggc tgtgactttt gtcgacaacc acgataccca acgaggacaa
    33901 gcccttgagt ctaccgttga agaatggttc aagccagcag cctatgccct cattttgtta
    33961 cgccaagacg gccttccatg tgtcttttac ggagactact atgggatttc agggcagtat
    34021 gctcaacaag atttcaaaga aatccttgac cgcctcctag ccatccgaaa agatttggcc
    34081 tatggagaac aaaatgacta ctttgaccat gctaactgta tcggttgggt acgttcaggt
    34141 gctgaaaatc aatccccaat cgcagtcctt atctcaaatg accaagaaaa cagcaagtca
    34201 atgtttgtcg gtcaagaatg gactaatcaa acctttgtag atttacttgg taaccaccaa
    34261 ggtcaagtta caattgatga ggaaggttat ggacaattcc ctgtctcagc tagatccgta
    34321 agtgtctggg cagtcaatac catctaatag ctcataataa ccaagctagg tccaagcgga
    34381 tttggctttt ttgtattcac aaaaagacct acccaaatgg atagatcttt acttgattac
    34441 aatttacctg ctactgcatc caacaattct tggatcttag cttggttgct tcctcctgcc
    34501 atggccatgt ctggtttacc accaccacgt ccatcgatga ttggtgctaa ttctttgaca
    34561 aggtttcctg catgaaggtc ttttgtcttg cttgctacaa ggacattgac tttgtcaccg
    34621 atagcagcaa ctaggacaag aagatcagag tagtcttttt gtttccagtt atctgcaaag
    34681 gtacgaaggg caccggcatc tgatacagac acttgactag caatgtagcg gtgaccgttg
    34741 acttccttca catccttgaa gatatcgcct gcggctgcag ctgcggcttt ttctttcaac
    34801 tcagcatttt ctttttgaag ttgacgaagt tgttcttgaa gtccttctac cttgtgaggt
    34861 acttccttga cttgaggtgc tttcaaggtt gctgcaacag ctttaagagc gtcctcttgt
    34921 tcacgatagg cttcaaaggc ttccttacca gtcactgcca agatacgacg agttcctgaa
    34981 ccgattcctt cttctttgac aattttgaag agaccaatct cagaagtgtt gccaacgtgg
    35041 gtaccaccac aaagttcaat agagtagtca ccgatagtca cgacacgaac ttccttgccg
    35101 tatttctcac caaagagggc catcgctccc atttctttag cagtgtcaat atccgtttca
    35161 actgtcttaa cttcaagagc ttcccagatt ttttcgttga cttgctgttc aatcgcacga
    35221 agttcctcag cagttactgc ttggaagtgg gtaaagtcaa agcgaaggaa ttcaacttcg
    35281 ttaagagatc ctgcctgtgt tgcgtggttt ccaaggatat tgtgaagggc agcgtgaagc
    35341 aaatgagtcg cagtgtggtt tttcatgaca cggtgacggc gattgctatc aattgccaag
    35401 gtatattctt ggttcaaggc aagcggtgca aggacttcaa ctgtatgaag ggcttgacca
    35461 tttggggctt tctgaacatt ggtcacagta gccacaacct tacctgactc atccaagatt
    35521 tgtccgtagt cagctacctg tccacccatt tcagcataaa atgacgtttc cgcaaagata
    35581 agagaggcag ttccttctga aacagcttct acttctgcat tgtccgccac gatagctacc
    35641 aatttagaag acaattggct agcattgtag ttgaagacac tttctacagt gatgttttga
    35701 agagtttcat tttgcatacc cattgagcca cccttgacag ctgaggcacg cgcgcgttct
    35761 tgctgttctt tcatggctgc ttcaaaacct tcacggtcta cagtcatacc agcttcttca
    35821 gcgatttctt cagtcaattc aactgggaac ccataagtat catagagttt gaagacatct
    35881 gaaccagcga taacagattg acctttttct ttcaagtctg ctacaatgcc ttgggcaaag
    35941 tgttgacctg agtgaagggt acgggcaaat gattcttctt cgctcttaac gattttctca
    36001 ataaagtcac gtttctcaag cacttctggg tagtagcttt ccatgatttt tccaacagtt
    36061 ggaaccaatt tgtaaaggaa aggctcgttg atacccaatt tttgaccatg catagaagca
    36121 cgacggagaa gacgacgaag aacataacca cgaccttcat ttcctggaag ggcaccatca
    36181 ccgatagcaa atgaaagaga acgaatgtgg tctgcgataa ccttgaagct catgttgtcg
    36241 ccatcttggt cataaacctt accagacaat ttctcgactt cacggataat cggcatgaag
    36301 aggtccgttt caaagttggt cttagcccct tggataacgg ccaccaaacg ctccaaacca
    36361 gcgcccgtat caatgttctt atgtggcaat tccttgtatt cgctacgagg aacagcaggg
    36421 tctgcgttaa attgtgacaa aacgatgttc cagatttcaa tataacggtc gttttcaata
    36481 tcttctgcaa gcaggcgaag accgatattt tctgggtcaa aggcttcccc acggtcaaag
    36541 aagatttctg tatctggtcc agaaggtccc gcaccgattt cccagaagtt gtcctcaatt
    36601 ggaatcaagt gacttggatc cactcccact tcaatccagc ggttgtaaga atctttatcg
    36661 tctggatagt aggtcatgta aagtttttca gcagggaaat caaaccattc agggcttgtc
    36721 aaaagctcat aagcccaagt gatagcttcg tcacggaagt aatccccgat agagaagttc
    36781 cccagcattt caaacatggt atggtgacgc gcggtcttcc ctacgttttc gatgtcgttg
    36841 gtacggatag ccttttgggc attggtaata catggatttt cagggataat ggtcccgtca
    36901 aagtatttct taagggttgc taccccagag ttgatccaca aaagagttgg gtcatttaca
    36961 ggaaccaaac ttactgatgg ttctactgag tgacctttgg tcgcccagaa atcaagccac
    37021 atttggcgta cttgtgcact agatagttgt ttcatattgt ctccttattc acttgtttaa
    37081 tgtgattggc tttccagcat ttccacatag tcaatcgcga cacagaggga aatgactagg
    37141 tctgcataag cgtcttcaag aaccgttacg gtataggtag aggtcagatg gaagagttcc
    37201 ttcttaattt ccgcaatcaa ctgatcgcga tcatccagca atttgaaatt caaatcccag
    37261 atattgccct cgatacgaag acctagatta tcaaactcat acttatctcg ccagaaggtc
    37321 aacttcttac gaatgacaaa actcgagcca tcccgaagct gaatctcaaa acgaggaagc
    37381 aaggtcaaga tttctttact aatctcactg acttgttcac cagccgcatc atagatggta
    37441 aaggttttag gaatcttaaa aaatgatccc tccacctgat aggcaatttc tcccctgtca
    37501 ttcttgatag cgaagcgttc gcctccaaga cgaaactttt gtttgacaag aaatgttttc
    37561 atcaacacct ccaaaaatca aaagacaagc tcatatcacg aagggcgaaa aaccgcggta
    37621 ccaccttcat tcaatgaact tgtcattctc ttgttcttat gcaattgtat gattgagtag
    37681 catgacttcc tagcttagat ggctcgcagc accgccattt ctctggacta agacaagtga
    37741 aaatcaattc tcaactttct tattatatcg tttttttaat cttgcgtcaa ctggaaatga
    37801 tctccgttga attagaccaa ttccctacat ctctgattac tttttcagga tatatttttt
    37861 cttactgcca tttttctttt tatcccaaat tttcatatta ctaaacacag ctactagaat
    37921 atttccaaat ataaaggtgc ctatcaccca atatatggac tcagttgtta ggtattgtcg
    37981 atccaagcca tcctttaaat ggaatagtat aacagtttgg ttaacaatca taaaggttgg
    38041 ccagaaactt tttttgaaaa aagtagacat tttcattatt tgttgccgct ttctgtaagg
    38101 ttaatactca ataaaaatca aaaagcaaac taggaagcta gcctcaagct gtacttgagt
    38161 acggcaaggc aacgctgacg tggtttgaag agtataggct tagtatacta ctaggcaagc
    38221 aaataagcaa ataaacaaat aaacaactag aatagaaaaa gatagggctc taaaaactga
    38281 cttctattcc ttaaaaacga accagcttga ctgattcgtc ttcttacgtt tatctcctac
    38341 ttccgataca ttttaaactg taggaagagg tcgctatatt tccctgtcca tttatggtca
    38401 aatttcttat aaacttctag gtgtttcatg gtttcaacat cgggatagaa ggccttatct
    38461 tcctttgttt cctctgggag caattccttc gctggtaggt ttggtgttga atagccgaca
    38521 tactccgcat tttggagagc attttcaggt ttcaacataa agttgataaa ggcataggct
    38581 gagttttggt ttttaactgt tttgggaatg accatattgt caaaccaaag attgctggcc
    38641 tctgtcggta ccacataacg tagattttca tttttttcta acatttggct ggcttcacca
    38701 gagaaggtca cgccgattgc aacattattc tgaatcatat agcccttcat ctcgtccgca
    38761 acgatagcct tgatatttgg agtcagtttg tagagcttat ccactgtctc ttccaactgc
    38821 tgcagatcct tggagttgag gctgtagccg agggaattga gtcctagtcc cagcacctca
    38881 cgcgccccat caaagagcat gatagaattc ttatactccg gcttccaaag gtcatcccaa
    38941 tgctcaggcg cttcatctac catggtttcg ttgtagacaa ttcctaaggt tccccagaag
    39001 taagggatgg agaatttatt acctgggtca aaggactggt tgagaaactc tggtccgata
    39061 ttttcgattc ctttaatttt tgaataatca agcggaacca agaggtcttc gtccttcatc
    39121 ttgttaatca tgtattcact tggaatggca atatcgtagg tcgttccacc ctgctttatc
    39181 ttagtgtaca tggcttcgtt ggagtcaaaa gtctcgtact gaacttgaat tcctgtttct
    39241 tctgtaaact gagtcaagag ttcaggatcg atatagtcgc cccagttata gataaccaat
    39301 ttttgactat ctcgactatt gattttacta tctaaatgag tcgcaattcc ccacaagaca
    39361 aggataatcg ctgcaattcc tgctaaaaat gaatagattt ttttcatgct tgctcctcct
    39421 tctcacgaga gataaagtaa taacctacaa ctaggataat actaaagaga aagactagag
    39481 cagacagggc attgatttct aaggaaatcc ccttgcgagc acgagagtaa atctcgactg
    39541 atagggttga aaagccattt cctgttacaa agaaggtcac ggcaaaatca tccagcgaat
    39601 aggtgaaggc catgaagtaa cctgcaatga tagacggagt caggtaagga agcatgattt
    39661 ccttaaacat ctgaaattga ctagctccca agtcataggc cgcatgaatc atgtcgccat
    39721 tcatttcctt gagtcgaggc aagaccatca agaccacgat aggaatggag aaggccacgt
    39781 gactagatag aacggtcaaa aagccaagtg aaaacttgag ttgggtaaag agaatcaaga
    39841 agctagcacc aatcataacg tcaggcgcaa ccatgaggat attattgagt gatagaaagg
    39901 cttcttggta tttcttacga gactggtaga tgtaaatggc accaaaagtc ccgataatgg
    39961 tcgctatcaa ggctgatagg aaggccaaga aaaatgtctg agccaaaatc agcatgagtc
    40021 tcccatctcc aaacatggtt tcaaagtgag tccagctaaa acctgtaaag ctattcatat
    40081 catcaccagc attaaaggca tagccaatca agtaaaaaat cggcaggtag aggaccagaa
    40141 agaccagtcc cagataaagg ttggcaaatt ttttcatcgt tctctccttt ccttggtcac
    40201 ccacatggtg atgaacatgg tcaggatgag aatcacaccg atggttgaac ccataccata
    40261 gttgtcattg gttagaaaat tctgctcaat agccgtcccc aaggtgataa cgcggttccc
    40321 accaatcaaa cgggtcagca tgaagagact caaacttggg ataaagaccg actgaacccc
    40381 acttcgcaca ccgttcatag atagagggaa gatgacatga cggaaggtct cccacttagt
    40441 tgcaccaagg tcgtaactag cattgatgag attattatcc atatcgtcta agacattgaa
    40501 aatcggcaaa atcataaagg ggagctcgat gtagcttgcg acaaagataa aggaaaaatc
    40561 ggtaaaaagc aactgttgtg aaccaattcc gataaattcc aagaattggt taatagagcc
    40621 attttgacca aaaatcccga taaaagcata ggctttaagg agcaaattga tccaggtagg
    40681 aaggataatc agcatgagcc agagttgacg gtgcttgaga cgggtcaaaa agagggctgt
    40741 tggatagctg ataagcaagg tcacaaaggt cacaatccct gcataaagca ctgagttgaa
    40801 actcattttg aggtaggtca agttttgtga cgcaaagtaa gatttataat tttctaaact
    40861 aaactggcct tcaatgttga aaaaggattg tccgaaaatc aagaccaagg gtgccaatac
    40921 aaagagggca atccaaagca tgtagggcac tacaaagagt ttagagcttg ttttcttcat
    40981 ctctttcctc ctcgatcgca ttgatcagac ctgcttcttg ctcttcgatt tccacgtatt
    41041 cttcgatacg agcatcgaac tcttcttcgg tttcattgag acgcatgatg tggatgtctt
    41101 ctgattcaaa gtccagaccg atttcctcac ccacgatggc cttacgggtt gagtggatca
    41161 tccattcatt tccaagttcg tcataggcga taatttcata atgaactcca cggaagagct
    41221 gggtgtcgac cttaacttgg agtttgcctt cttcaggaag ggtaatgcgc aagtcctctg
    41281 gacgaataac gacctcaaca ggttcatttg gcttcatccc accatcaacc gcttcaaagc
    41341 gtttgccgtt aaattcgacc aagtagtcct caatcatggt acctggcaag atgtttgact
    41401 ccccgataaa ggtggcaaca aagtggttga ttggctcatc gtagatgtcc acaggggttc
    41461 cagactggac aatctcgcca tcattcataa cgaaaatcca gtcactcatg gcaagagctt
    41521 cttcctgatc gtgagtgaca aagacaaagg taatgcccaa tcgttgttgt aattcacgca
    41581 attcgtactg catgtctgtt ctcaatttca agtccagcgc tgataaaggc tcgtccaaca
    41641 agaccacacg gggttggttg atgatagcac gggcgatggc cacacgctga cgttgtcctc
    41701 cagaaagttt gcggatggaa cgtttttcat aaccttccaa ctgaaccatc ttgagaactt
    41761 ccgctacacg ctgctcgatt tctttcttat caattttacg caagcgaagt ggaaaggcaa
    41821 cattttcaaa cacattcata tgtgggaaca aggcatagga ttggaagacg gtatgtacgt
    41881 cgcgcttgtt ggttggaata tcattgatac gaacaccgtc tagcatgata tctcctgtcg
    41941 tcgcatccag taaacctgca ataatgttta ggatagttga tttccccgaa ccagatgcac
    42001 ctagaagggt gtagaatttc ccttcttcca actcaaagtt gatgtctttg agaaccttgg
    42061 tgttgctgtc ttcaaaaact ttagagacgt ttttgaattc gataattggt tttttcaatt
    42121 ggcataaatt ccttcttttt catagattaa ccgatcgggg ctctgtcagg tccccactac
    42181 ctcttgcagg gagtaaaacc acctgcatac atcttcgcta ccgataggct ttcaccccct
    42241 ttccatgaca tagcagcagc ttttcaaata cagcttccta cttgctttca cccaagatcc
    42301 ggacttctct ttcaagcgta atacctgagt gttccttgac tttttcgata accgattgga
    42361 tcaagtcctc gtagtctttg gccgttccat ctgcgacatt gatcataaat cctgcatgct
    42421 tttctgacac ttctacgcca ccgatacgat agcctttcaa gccagcttct gaaattaact
    42481 gacctgcaaa atgcccgact ggacgcttaa agaccgagcc acaagatggg tattccaaag
    42541 gttgcttgag ttcacgtagg tgcgtcaagc ggtccatttc ctgcttgata acctgatggg
    42601 ttcctggggc tagggcaaat ttaactgaca agacaactgc accagactcc tgaatagctg
    42661 aatggcggta accaaaagcc aagtctttag cagacagggt ttcgatttct ccatccttgg
    42721 tcaagacctt acaagactgc aagatgtgag caatctcgcc accataggca cccgcattca
    42781 taaagacagc accgccaacg cttcctggaa taccacaagc aaactcaaag ccagtcaaac
    42841 tatgacggag ggcaatgcga gttgtttcaa tcaagttagc cccagcttct gcttcaatgg
    42901 tatagccatc aacagaaacg ttattgagct tgtcacacaa gatgacaaat ccacgaatcc
    42961 caccatcacg aacgatgata ttgcttgcat tgccaagaac catccaaggg atattttctt
    43021 ggttggcaaa tttcacaagg cgcgccaact caaaacgatt tcgtggaaag accaaataat
    43081 cagcctctcc acctactttt gtataactat agctatgcaa gggttcctta aaacggatat
    43141 caattccttc taagatttca agcatttttt ctcttacaga catgtcactc ttccttttac
    43201 aaaattcatt ccattatacc atttttagag acatttgacg accataaaaa taccttgttt
    43261 ggattttgca taagaaaaag aggttccccc ctttttatga ttttttacaa aagatttcct
    43321 tggttccata ggcgaccaga acgagctcca gtgctagaat cacttcaacc aagactggat
    43381 ttgtcaacca gcctacttgg aaaagagatg gtgccagatc aaagaaggca tgcaagccat
    43441 aggctgctag gagataaatc catttcttct ggcgaacagc ttggtaaacc caaactgtca
    43501 aaagtaattg gaaaccaagc gccaagattc gctcaaaacc aagcaaataa atctgccaga
    43561 ccgaaagtga ctgaatggtt tttaacatat tttcagacag taattgcata acctgtggat
    43621 tctgagtttg aactgccgaa agaacgatgt aaagattgag taaactaata aggcctagaa
    43681 aaatcaactc caagccacca tgccctaggc cataggccaa ggcatctgcc ttttccaaac
    43741 ttctcttttt ctccaaccat ttgaagaaaa caagacgagc cgtttcctca aaaaatgctg
    43801 ccatggctag gccatagata atatagataa gcggatgatc ttgcaagagg gcaatactac
    43861 cgtctttttg agggtgcaaa atcaagatat gcaccagttt ttccaaaatc tgcgaagaga
    43921 caaagaaagc gactgcaccc aagcccaaga cagctagatt aatctggtat ttctttttgg
    43981 caaaccaaat gcttcctatc agaaaagcta gcaacagcaa catggtaata atgatatgaa
    44041 tggtcatttt cttctcctat tctgcctttt caatatcttt tttcatctcg tcaacattga
    44101 acttagcaaa caagtattga cggtcttgga ctgggaaacg ttggtccaac tggtcaactg
    44161 ctcccacctc gataatgcct tccttgatga caaaatccat gacatgtcca ccgaaggtca
    44221 aatcatctga tatgaagtgc agatggtagc ctgccacact gaccccatgg aaaatctcag
    44281 gcgtccagaa accaacaata gtccccgcaa cattgtcacg actatattcc ggttgatggg
    44341 ttgcgacatc agcaaactta gtatcgggtg ttgacttagg aatcatacgc acatgcatat
    44401 gtgaaaattc tccccgaatc ttgatagaac ggaaaagatt ttccccatca taataagact
    44461 caattcgttc tttcaattcc ttgtctgtca tctcaaagcg ctggcggaaa atgacctctg
    44521 cctgatgcgg taccactgca gcgtaaggaa taagggcatc tggtgacact tccacaattt
    44581 ctggctggtc tcctgaccct ttggcctgat aagccttgcc atccaagaca atcaattccc
    44641 catcaataga atccaaggtt cccaaaccaa ggtcaccatg ctctagcaat tctcccactg
    44701 tcatggtacc accataaagg ccagccatca aggctccaag agtattgtat tgaaataatt
    44761 tcactggttc ctgcacgttc ttatccattc actttcttgt ctgttattct ataaatctta
    44821 ctcctaagta taccacattt gcccctagat gtgaacgaga gaaacgctct agacattgcc
    44881 aagaaggaaa aaaaagggta caatgtaaca aaatcaaggg aggtctggaa tgaagaaaca
    44941 aagcaagtac aaagaggtcg tttcctatct gaaaaatggt atcgagtctg gacgatttcc
    45001 gacgggtagt cgcctgcctt ctatccgtca actgagcctt gactttcact gtagcaagga
    45061 caccattcaa cgagccctgc tggaattacg gcacgaacaa tacctctatg ccaagcccca
    45121 gagtggctac tatgtcctag aacaagggca acaccaggac ctagaaatcg aggttaccga
    45181 cgaacatgcc agtgcctatg acgatttccg actctgtgtc aatgaaacct tgattggccg
    45241 agaaaactac ctcttcaact actatgataa tcaagaagga ttagaagacc taagacaatc
    45301 cattcacaaa ctcctctttg agcaagctct ctactgcaag gctaaccaac tagtactgac
    45361 ttctggaacc caacaagcct tgtttatcct ctctcaaata tcctttccta gccaagccaa
    45421 ggaaatcttg gtggaacagc caacctacca tcggatgaat cgcctcttga ttgcacaggg
    45481 gctggactat caaacgattg aacgaggcat tgatgggatt gacctgaagg agctggagcg
    45541 acacttcaag acaggaaaaa ttaagttttt ctacaccatt ccccgatttc actatcctct
    45601 gggacattcc tattctgagc aagacaaacg atccattctt aacttagctg ccaagtatga
    45661 tgtctatatc gtagaagacg attatctggg tgatttggac tccaagaagg gccaaacctt
    45721 ccactatctt gatacagagg agcatgtcat ttatatcaag tccttctcga ccagcctttt
    45781 tcctgccctt cgtattacag cactcattct tccaaatgct atcaaagaag catttgtggc
    45841 ctacaaaaat atcctagact acgacagcaa cctcattatg caaaaggccc tgtcactcta
    45901 tattgacagt caattgtttg aaaaaaatcg tttggctcgc ttgaccaatc atgaatctta
    45961 ccaaaaacaa atcgaggaaa ggataactaa aacaccttgt ccccttcctc attatcccct
    46021 acacgatggt ttattgctag acctgagaca gtatcctaaa atcgccagtc tcaaacacag
    46081 tcaaccgggc ttggacttct ttgaagaggc ctatttaagt acctgtcctt atcaatttgc
    46141 caaggtgtcc ctagacaatc tggaaaatgt tttaaactat ttaaaagcag aattggaatg
    46201 acatccaact ctgctttttc ttattcttca acttcagtta gacttgctgc tttttcaaga
    46261 tagctttggt aaattccttc atccttaagt ttttggatga ccttgtctac cacttctttc
    46321 aaatcatcac tattttttct aagagcaacg gcattggcgt cgccgtcctt catcttcaag
    46381 ctgacagttg cgacagctaa gccagcgttt ttagcagcat aactaagtgc aacaggctca
    46441 tccatatgaa cagcatctac ttttccagcc tgcaattcat tgactgcttc acccatatta
    46501 gttagggaag ttaattgagc ttttggcaat tgttccttga ccattgattc tggaacagtc
    46561 cctttttggg ctgcaatatt agcactttct aggctagtta aatccttgta tttttccaca
    46621 tcagccttac gaaccaagaa actaatcttg ttttcatagt atgggattga aaaatcaaag
    46681 acttcttttc tctcgtcagt agcactaatt cctgcaactg ctaggtcagc cttaccagtt
    46741 tgaagactgg tcaaaacatt gtcaaaactc atgcttgaga tttccaactt aaccccaagt
    46801 tcatcagcga tagcctgagc catgtcgatg tctgcaccga ctacctggtt ctttccatca
    46861 accaatgatt gaaattcaaa gggtgcatag tcaggactgg ttgccacaac taatttcccc
    46921 ttttgcttaa ttgcctcaac agctgactga gaaccattag aacctgactg gcaagctact
    46981 aagaagaaac ttgcaagaaa attacataaa acaaatatcc atttttttga tttcataaat
    47041 aaacaacctc tctgttaatt ttgtataatt ataacgatat ccaagttact tgtcaagtgt
    47101 tttttaaatt tttatctcaa aaatattttt tcgttcaaaa aaaggagcca tcagttgatt
    47161 tcaagctcct ttttatacag aattaaacta ttttatagtt cgacaatctt acctgtttca
    47221 aagtagacaa cccattcaca gatattttta gcatagtcac cgatacgctc caagtaggaa
    47281 ataacttgga aataatcacg acccgtaaca atggcttctg gatttttctt aatctcttca
    47341 gtcgcaaggt cacggatagt ttcaaaatag tggttaattt gctcatccat ggaggccacc
    47401 cggtatgcgt cgtcaacaga accattaaga taaagatcaa gtgctgcttc aacaacgctt
    47461 ttaacttcac gtcccatttt tttaatttct tcctctacag ctggaatacg ttcttccccc
    47521 ttcatacgga tggttgcctg ggcaatggct acagcgtgat cccccatacg ctccacatct
    47581 gatacagcct taaggacagt caagactgta cgcaaatctt gagagactgg ttgttggagt
    47641 gcgatcattt caaatgattt cttttccagt ttcacttcgt attcatttac ttctgcatca
    47701 tcttcgatga cctcttttgc caggtcacgg tcatgcgtga caaaagcacg taccgtacga
    47761 ttgatttgtg agagcacttc ttgtcccata gcgtagaact ggttatgtaa tttctctaaa
    47821 tcttcttcaa attgagatcg taacatcttt catctcctta tccaaatttt cctgtaatat
    47881 agtcttccgt ttccttgtgt tggggatcaa ggaacatctg cttggtatca ttaaattcaa
    47941 tcaaatctcc atctaggaaa aatcctgtct tatcagagat acgtgaagct tgctgcatgg
    48001 aacgggttac cagaagcatg gtgtacttgt cttttagacc atacaaggtt tcctcaattt
    48061 taccagctga aatcggatcc aaagccgaag ttggctcatc caagaggatg attttaggac
    48121 tagttgccaa gacacgggcc acgcagacac gctgctgttg accacctgac aatccaatag
    48181 ctgaatcata tagacgatcc ttgacctcat cccagataga ggcaccttgc aaggcttttt
    48241 ctacggcttc atccagaacc tgcttatcct taattccatt gatacgaagc ccgtagacaa
    48301 cattctcata gatagtcata gggaaaggat taggttgttg gaaaaccatt ccgatttcct
    48361 tacgtaattc aaccgtatct gtacgcggac tgtagatgtt gtgaccattg tacaccacgg
    48421 atccagttgt ggtcacctct ggattgagat ctcccatgcg gttgagagac ttgaggaggg
    48481 ttgacttccc tgatccagat ggaccaatca aggctgtaat ttccttaggt tggaaagata
    48541 gggaaacact attcaaagcc ttctttttat tataataaac ggacaggtct gatacctgta
    48601 aaatcgcatc tgtcatacgg tttcctttct aaccaaagtg accagataca tagtcattgg
    48661 tggactgtag cttggcattt tggaaaatag ttgcagtctt gtcatactca atcaaatcac
    48721 ccaagtaaaa gaagcctgta tagtcacttg cacgagcagc ctgctgcata ttatgcgtta
    48781 caatgatgat ggtaaagttt ttcttgagct caaacatggt ctcttctagt tgcatggtcg
    48841 caatcggatc caaggctgag gctggctcat ccattaagag gatatctggc ttaacagaga
    48901 tggcacgagc gatacagaga cgttgttgct gaccacctga taaggtcaag gctgacttgt
    48961 ggagatcgtc tttaacctga tcccagaggg cagcctgacg aagggaggtt tctacgattt
    49021 catctaggac ttgcttatcc ttaactccag cacgttcatg cgcaaaggta atattacggt
    49081 aaattgactt agcaaatgga ttggggcgtt gaaaaaccat tccaatgtgt ttacgcattt
    49141 cataaacgtt gatttctgga cggttgacat caattccacg atagagaatc tgcccagtta
    49201 ctttagcaat atcaatggta tcattcatgc gattgagact gcgtaagtag gtagatttcc
    49261 ccgatcccga cggaccaatc aaagctgtaa ttttatttct ttcaaattgc atatcaatcc
    49321 ccttaatgga ttcattttta ccatagtaaa catggacatc cttagtagaa agggctactt
    49381 tttcttcagg aaaggtaagg atatgcttct catcccagtt atatgttgac atggcttctc
    49441 ctttaggcag cggttaattt cttgtgtaga tagcttccga acttacgagc tccaaagtta
    49501 aaaatcagga taaagatcag gagcacagcg gcagaacctg ctgatacaat ggttccatct
    49561 ggaatagtgc cttcactatt gactttccag atatggacag ccaaggtttc tgcttgacgg
    49621 aagatagaga tggggctagt cacactgagg atattccagt tagaccagtc aagagctggc
    49681 gccgattgcc ctgctgtata gatcagagct gcagcttcgc caaagatacg accagatgcc
    49741 aagacgacac ccgttacaat acctggaagc gcttctggaa taacaacatg aaccactgtc
    49801 tcccagcgag aaatcccaag agccagacca gcctcacgtt gggtatggtg aacgtgtttc
    49861 aaactatcct ctacattacg cgtcatctga ggcaagttaa agactgtcaa ggccaaggca
    49921 cctgaaatga ttgaaaaccc atactcaaac tggactacaa agatcaagta accaaagaga
    49981 cccaccacca ctgatggtaa agaggacaag atttcaatac aagtccgcac aaagttggta
    50041 acaggacctt ttttagcata ttcagccaag taaatcccag ctcccataga aagaggtaca
    50101 gaaataatca aggtaatgac caataggaaa aaggaattgt aaagctgaat gccaatccca
    50161 ccacctgctt gaaaagcaga agaccttcca gtcaagaaag accaagagat atggggcaag
    50221 ccccgaacca agatatagag aattaaggaa gccaagattg tcacaatgat gctagcaatc
    50281 gtatagagga cagctgttgc aagtttatct aatttcttag cgcgcataat ttttctttcc
    50341 tctttctttc gtaatcaatt taatcacact gttaaaaact aaactcatca agagcagtac
    50401 caaggccagt gaccagagaa cattattatt tacagttccc atgacagtgt tcccaattcc
    50461 catagttaat atagaagtta aagttgcagc tggtgtggtc aaggaagttg ggataacagc
    50521 tgagtttccg acaaccatct ggatagctaa agcctcacca aaggcacgcg ccatcccaaa
    50581 gaccactgca gtgaaaatac cagaacgggc cgccttcaag atcacacgcc agatagtctg
    50641 ccagcgagtg gctcccatag cgaaactggc ctcacgataa taacgaggaa ccgcacgcaa
    50701 gctatccgtt gtcataaagg ttacggtcgg caaaatcatg acaaagagga cggaaatccc
    50761 tgacaaaatc ccaaaaccag tcccaccaaa gacactgcga acaaagggaa cgacgacttg
    50821 caagccaata aatccgtaca ctactgaagg aatcccaacc aggagttcaa tagctggttg
    50881 caaaatcttc gccccttttg gtgatacttc ggtcataaaa actgctgcac caatagcaaa
    50941 gggtgttgcg ataagggctg agagaatggt aacgataaag gaacccaaaa tcataggaag
    51001 ggcaccaaat tctttactag aaggattcca agttcctccc aaaagaaagt caaagatatt
    51061 cacaccattg acaaagaagg tcgacaagcc tttttgcgct acgaaaacca aaatcatggc
    51121 cacaaggatg actatcaaag aaagacaggc aaaggtcaaa ccttttccta atttctccag
    51181 acgagaattc tttgatggaa gcaacatttt cttagctaat tcttcttgat tcattattgt
    51241 ctcccttcca acactgtcac agttccggca gcatcttttt caaccttcat ttccttaatc
    51301 ggaatatact tcaatccttt gacaatccct tcttgggtct catccgagag aacaaaattg
    51361 agaaattctg cagccaactc attgggctgc cccaatgtat acatatgctc ataagaccac
    51421 aagggccaat tattgctact tatattttct ggacttaagt catagccatt caacttcatg
    51481 cttttgaccg aatcatctat ataggtaaga gataaataag agatagctcc tggacttttt
    51541 gatacgattg attttaccgc tccatttgaa tcctgctcct gactttgcat ggcagactga
    51601 ccttccataa tgacagtatc aaaggtagca cgagaaccag agccggctgc ccgattgata
    51661 acagagatgg gtaagtcctt accaccaacc tctttccaat tggttacctc acctatgaag
    51721 atttgacgaa gttgctctgt cgttaggtta tcaacatcaa cctccttatt gacaatcaga
    51781 gccaagccag ctaccgcgac cttgtggtca acaagagcag aagcatcaat tccgtctttt
    51841 tcctcagcaa atacatctga gtttcctata tcaactgccc cagactgaac ctgggacaag
    51901 cctgtaccag aacctccccc ttggacattg accgtttttc caacatggat cgtgccaaat
    51961 tcatctgccg ctacttcaac caagggttgc aaggcagttg agccaacagc cgttatggat
    52021 tctccacgat caatccagct agcacagcct actaaacaag ccgtcagcca aaaagcgata
    52081 agagacagag caagcttttt tctttttttc actgtttttc tcctcgaaaa taattatgaa
    52141 tactgtgaat tttttaagta gttctttatg agttgacgca tgaattctta ccaaatttct
    52201 gcgcaattga ttatttatat aatataggct atattactct ttcctaacct ccttttttca
    52261 tatgtggata aaatctcttg tctatccctt cccccattgt cacccattat agtcatttcg
    52321 tgtctctttt tccccttttt aatgcaaggg aaattactct ccttagatga taatccaaaa
    52381 gctagaaagg tatctcaaac ctctctactc tcccagacta gtttacaact aaaaggaaaa
    52441 gattctattt tatgagaaat ctagtttaca agcggtaaga acgctaataa ctaaacttct
    52501 tgtactcttt gaaaatctct tcaaaccagt gttttgagct atctatggct agcttcctag
    52561 tttgctcttt gattttcatt gagtagtaaa actacatgta atggcaatca agatatcaag
    52621 aatcatccta ctaaaaaaat ccatactttc actataacat agaataagat atttgactag
    52681 cattttcatt tgaatctgag gccttttgga aaataatttt tcaaaacatt tccagtaacc
    52741 tttgcaaagc ccaagccatt gcctttaacc aaaacttggt accaaccatt tggcagactt
    52801 tctgccagct gaacgatttc tccagccgca tacttgacaa acgcttcttg gccaatttca
    52861 accgactgtt cgacctgact cggtttcaag gctaaaccaa gagcgaaact gggctcaaag
    52921 cgtttcttct taaaagtgcc cagatgcagt ccattgcgag caatcttgag cttccctaaa
    52981 tctggcaaaa gttctggcaa gagataaagc tggtctccaa aagtctgcaa gatacccggt
    53041 agattgacct tcaaatggtt ttgggcaaat tcctgccaca aggcaacttg ttcacggctg
    53101 aggttactct tacttgcctt aaatttagga gctggattgt tacccttaaa ctgtagatgg
    53161 gcaacaaact gaccctctcc cttaaactga tgagggtaca tccgagccgt ttctggcagg
    53221 tcaataccag ctaccattcc attgatatgc tctactggca acaagtcaaa atcatactct
    53281 tccagcaacc aattgacaat ctcttcgttt tcctcgggtg cccaggtaca ggtcgaataa
    53341 accagacgac caccttcagc taacatggtc actgcatcct ccagaatttc tctttgcaag
    53401 ctagcacatt gactcggata atctaagctc caatagtcca tagcatcagg ttgcttacga
    53461 aacattcctt caccagagca aggggcatca agaacgatta agtcaaaata gcctttaaag
    53521 accttgacca agcggtcggc agattcattg gtcaccacga catttgtcgc tccaaaacgc
    53581 tccatgtttt caaccaaaat cttagcccgt ttgcttgaaa tttcattgga aacaagtagc
    53641 ccctcccctg ctagataggc tgccagttga gttgatttgc cccccggtgc agcagccaag
    53701 tccaagacct tcataccagg actgggttga gctacttgag ccaccatttg agcagcaggt
    53761 tcttgcgaat aaactaaacc tgtagcatgc tcaggcgatt tccctgaaac cttcccatag
    53821 tggccccaag gggtttgagt aatggcatca gaaaaggaaa gttgctcttc ttttaaggga
    53881 ttgacccgaa aggccgaaac cgcttcctcc tcaaaagagg caagaaaatc tcttgcctca
    53941 tctcctagta tctctttata tttttcaaca aatccttctg gaaattgcat ttaagttctt
    54001 ttcctttcgt aaatatagga ctgaatttcc tcctgcatct caagaggcac catcatgacc
    54061 ggctgtctgg tttgaaaatc aggagcttca ccaaaaaggg tcacaacccg atagcccaga
    54121 ctttccccta aaatactagc tgcggcataa tcccatggtt gcagataagt gagataggtc
    54181 aacaaacgcc ctgacaaaat cttggcaaaa ctaatggccg cacttccata gacacgaaca
    54241 ccaagaaccg ctcggctcaa atcagccagc ccccattcat tggtttccag cataccacta
    54301 ttccctgcaa tgagaaaatc tccaagtggt ttagttttaa aaggagctag gggcctatca
    54361 tttagacaaa ctggaaattc cccaccaccg tggtaacaat cccctttgac cacatcataa
    54421 atcagaccaa actgtccctg accattttca aaataagcca tcataacagc aaaatcttcc
    54481 tgctgggcta caaaattatt ggtaccatca atgggatcaa tgacccaaac cttgccctct
    54541 tgaaccgagg ctcgcagaca accttcttca gcacaaatct tatcctcagg ataacgggac
    54601 aaaatctcac caaccaagag ttcctgaact tctttgtcca gtctggtcac caaatctgtt
    54661 ggagaggact tggtttcaac acgcaagtct tcctgcatat ggtcaagaat gtactgacct
    54721 gctttcttaa caagctcttt agcaaattca aatttacttt ccaagagaaa tctttccttc
    54781 ccctttttct ttggcagcct gaactgctcg gtaaagtgaa tagccactaa ccgtttcaaa
    54841 ttctcgtccc aaacgtttct cttcgctctt gcttggcacg accgctttga atcccttata
    54901 ggagtccagt aactttttag cctctacttt gccttcatag gcagcttcaa catcattaaa
    54961 aaaagaaagc actgaagcaa gttcttcagt gctccacgac aaatctagtg ggtaactata
    55021 ctgtttgttc attaactaat accagctctc attcttgctt cttttagttc ttgcttacga
    55081 taactacgag ggagaaaagc acgaatctca tcttcattaa aaccgatttg catacgcttg
    55141 gcatcaataa taattggacg acgcaaaaga ctaggatact gctcaatcaa atgaagcaat
    55201 tccgataccg aaatactctc tacatcaata ttcaattttt gaaaaatttt tgaacgagtt
    55261 gaaatgatgt catcagtacc attttcggtc aaggaaagga tgtgttgcaa ttcttttctt
    55321 gttaaaggac tggtcataat attgtgttcc acaaagggaa ccttatgttt ttctaaccag
    55381 gccttagcct tacgacatga tgtacagctc ggtgatagaa atagtgtaat catgcttttc
    55441 tcttcttatc tatactttgc tacttctatt atacaaaaaa ataaggcgct tgactaggga
    55501 tttttagaaa aaaagcctat tttttcaaga aaaataggct gtttgcgaac gattgacaca
    55561 attggatttg gttaattcac tcttaacgat ggttttaaac gatatatatt tttatatatg
    55621 caaattaaaa acatctttca tttcacttcc tacgactttt cagacacaga tagccaaaga
    55681 agctttcata gagggcaaaa aagaggagga aggcatgaag aaagaaggtc tctggcaaaa
    55741 tcataataac aggatccttg gctggatcaa aaagccaggt atcatctccc acaaagagaa
    55801 tttgatggaa aagagtaaag aattggtcaa aaccaatcaa aactccccca agtccaatca
    55861 tcacaggtaa gactactaga gccaggagac tttttcgata aagagacaaa aagtcctttt
    55921 tcacaatcct attgacaaag acatagaaac ttggcagtgt cactagagct actagctgaa
    55981 ccaaatgaaa gagattcttg accactgcga aatggtgcag accagctgct gacgaacgaa
    56041 aatcaggcat ctgtaagacc tgactaaaag gattggtcag ataattcatc aagatatgaa
    56101 aattgtattg aatggtttct ggttttagat agactcgatt cgttaagttt agccactgaa
    56161 tctccatagg atagaaaatc caagccagat aaatggtcag aaggattgag agggagagga
    56221 gaaagagcat agagccccaa aaggtcaatt tagttttcat caaaatccca ctccgcaagg
    56281 ctagaaacca catgtgtcgg tgcgattggc aggccagcta cttcttctgc cttggtaaaa
    56341 cctgtcgtca ccaagagcgt tggaatgcca ttgtcaatcc cagcccggat atcagtcaaa
    56401 taattgtccc caaccatgat taactcttca cgttccaaac ctaagtgctc aaccgccttg
    56461 tccataatga tggcatttgg ttttccgata taaaccggct tcactcgtgt cgctacttca
    56521 agcagcgtaa tcagtgagcc agcacctggc aaaagaccgc gttccgtcgg gatgttgagg
    56581 tcaggattgg ttccgataaa atgggcaccc ttttgaatag caagagttgc tgtggcaaat
    56641 ttttcatagt cgacttgcca atccagacca actaccacgt aggcaggttt ttccttgtct
    56701 tccacataac cagccgcctt gatgacttcc ttgagtcctg cttctccgac gacatagacg
    56761 gtcttttcaa gccccaaatc attcatatag tcgatggttg ccaaagtcgc tgtgtagaca
    56821 gtcgataggg gcgtatcgat attaaaattc tgagccaaca tctccttaac actctctgga
    56881 gtgcgggttg tattgttggt tacaaagaga tagggaatgt cccgcttttg caattcatga
    56941 acaaaagtct ctccagcagg gattcggtct ttccccttat aaatggttcc gtctaaatca
    57001 attaaatagc ctttatattt catctatttc tccctaagcc ttttttattt cttgccaagt
    57061 aatgattgct tgggcattga taaccccatc acttgtaatt tcatgcttgc tttccagtcc
    57121 agtccgttca acagccgatg taatcacccc acctggtcga acttccttga catacttgag
    57181 gttgattttc ttgggaatat agtgggtcaa aaaatccgct cccatgacct caaaaatcca
    57241 gtccaagtat ttactgttat tgacatgacc attcatatcc aagtcgtaaa aacgaacatg
    57301 gtaatccttg ctgatcggtt cttccaagga ctcatacttc ggtccacgga taagtttttt
    57361 atcaaaatca gactggtaag gagccacaat ctcaggttca acaacatgga cttttcgact
    57421 gtcgcggtcc atgagaacaa aggtcgccat catgtggatg agctcctgct ccgcttcatt
    57481 ataaatagta aagcgacggt agcaaaaaag tcgattgtag ctcaaggctt ccgtttcgat
    57541 ggtaatttct tccgcaaaac gaggcaaacg aaccacctca atatcatatt ctacgataat
    57601 ccagaccaga ttatattctt ccaaaatggc cttatcacta actcccagtt caatcgactg
    57661 catccctgaa acttgcagtg acagcaaaat cacatctgga agtttgatat gaccgttcat
    57721 atcagccata tcaaaaggaa ttttcatttt catttgataa gttaagccca tgatcctact
    57781 ccaaaataaa tcgttctgct acagtatctc ccaaaaagag acctctcttt gtcatgcgaa
    57841 cgtggtcacc ctcaatctgc atgaggcctt gttgaaccaa atctctgaca atttctccat
    57901 aaagtccagc aaaagactgt ccaaattttt cctcaaatcg cgccatggaa accccggatt
    57961 tcttgcggag tcccaagaac atttcttctt ccatttgctc cttttgactc aggtgatctt
    58021 ctgtaataca agcattgcct tcctcaaccg cactgagata atgacgaatg ggaccatgat
    58081 ttttatagcg tactccattg acataaccag atgcccctgc accaatacca tagtattcag
    58141 cattgtccca gtacatgaga ttgtgacgac tttcaaaacc gggtttggag aaattagaaa
    58201 tctcataatg ctcaaaaccc gctcgctcca gctctgcaat gatgtactca aacatctccg
    58261 cttctagttc ctccttaggc agaggcaatt tcccacgtcg catccggttc ataaagaccg
    58321 tatggttttc taaaatcaaa ctatacaaac tcatgtgggg aatatccagt ccaatggctt
    58381 tagccacatt ttcctttact tgctccatgg tctgaccagg cagagcataa atcaaatcaa
    58441 tggagatgtt gtcaaaacca gccagtttca gacgatcgat attttcataa atatccttct
    58501 ccaaatgact gcgcccaatc tttttcaaca tcttatcatc aaaggtctgg acacctagcg
    58561 aaacacgatt gacagccgaa tttttcaaaa cagctatctt atccgcatcc aaatcgcctg
    58621 gattggcttc aatggtcaac tcttccaaga cagacaagtc caagttttta gtcaagccat
    58681 tcagtaacac ctccagttgc ggagccgaca gggctgtcgg tgttccacca ccgatataaa
    58741 gggttgacaa cttttcaata tcataagaac gaaactcttc cagcagatgc tctaaatagc
    58801 tgtcgactgg ctgatttttg atgaagacct ttgaaaaatc acaataataa caaatctggg
    58861 tacaaaatgg gatgtgcaca taggctgacg ttggtttttt ctgcatagta attattatac
    58921 cacaaagact agattccaga taaaaatcac catccccaga tacatagtcc gtccggagat
    58981 ggtgatggtt tattcttctg ttatatcaat cacaatctct tctgagtcat caagagcttc
    59041 ggctttttct tgccattgtt ccttgagatt atttaattga ttttttgatg cttctgtcgc
    59101 ttgaaaagca taggatttag cttgagcaag tatactgtcc acagtgattt cacctgactc
    59161 aacctgttct tttgttttca gaacaaaatc tgtagcctgc tccttaactt ctgtcagttt
    59221 ttcacagact tgctccttgg catactccgg atcttctctc aaatcatcta gaaaatcttg
    59281 agcctgactg caaacttgtt tgcccttatc acttgttaaa aacaaggcaa gagctgcacc
    59341 tgaaaccgtt cctaaaagga ttgaggataa tttacccata aggattctcc ttttttattt
    59401 tttgaaaaat ttacttgcaa gacgaagagc tgacagactt gcaccagtct tgagtgtttt
    59461 tgaaccagct gatgaagctt tcttgctcaa gacacgcgca tggtcattga ggtctgaaac
    59521 agatagagat aaatctgcaa cagcactgaa gagtggatca atcgtagcca ccttgacatt
    59581 gatatcatct gccaagacat tgaccttagc caacaactca ttggtgtgat gcaaggtcac
    59641 atccacatct gaagtcaagg ttttaatcgt cttttctgtt tcatcgatga cacgaccaag
    59701 cttttgtaca gtaatgatca gatagaccaa aaagacaatc aaagctaggg caacaagaat
    59761 atatgcaact tctaacattt atttttcctc ctctgtaata tagtaagggg ccttctttcg
    59821 attttgataa ataacgatca ttataccgag accgataagg acaactgaca gccattggga
    59881 cactcgaagg ctgaagaaca tgagactatc tgttcgcata ccttcgatga ccatacgacc
    59941 gaaaccatac caaatcaagt aaaaggccgt gatatgacct cgtctgagac tcttccattt
    60001 ccgtctaaaa atcagaatca aagcaaagcc aagcagattc catagagact cataaaggaa
    60061 agtcggttga cggtagctcc cctcaatata catctggtca cggataaagc caggtagata
    60121 atccagatta tccactgttg caccataagc ttcttggtta aagaaattac cccaacgccc
    60181 caaactttga gcaatcataa cgctaggcgc cgcaatatct agaaaatccc aagtattgat
    60241 gagtttacgg tcagcaaaga tatagagcac aagagcccca gttatcaaac caccgtaaat
    60301 ggccaaacca ccattccaaa tggcaaaaat ctctcctaaa ttctgactat agtaatcaaa
    60361 tcggaaaata acatagtaga gacgagctcc taaaatagcc aagggaaagg ctactaagat
    60421 aaaatctaaa atatcgtctg gtatgatctt ctttctaggt gcttctttca tggtcaaata
    60481 aaccgcaaga atcaagcctg tcacaataca taaggcatac caacgaatgg ctaggggtcc
    60541 tagttgaata gcaattggat caagcatttt gcacctcatt tcgagcaatg agacttgtca
    60601 gtcgttcgtc gaacaaacgg gtcgcatcaa agcccatttc cttggcacga taattcatgg
    60661 cagctgcctc aatcacaaca gagatattac gacctgtttt aactggaata cgaatacgag
    60721 gaatggctac gccagaaact tcaagttcct ctgcattgtt tccaagacga tcaaaggtct
    60781 tatgtgtatc gtaattttcc aaatagacag caagctgaac ctgtgaagaa tccttgacag
    60841 cactcgcacc gtagagactc ataacatcga taataccaac cccacgaatt tcaatcaagt
    60901 gtttcaaaat ttcagctggt tcaccccaga gagtaatctc atccttggca aagatatcga
    60961 cacggtcatc ggctaccaaa cggtgaccac gtttgacaag ctcaagacct gtctcgctct
    61021 taccaattcc actatctccc tgaatcaaga cgcccatccc ataaatatcc atcaagacac
    61081 cgtgcacact ggtacgttct gccaaacgag aatccagata gctagataac tctccagata
    61141 aacgactggt agctgcacgg ctggttaaaa tagcaatctt acattctcta gcagccttta
    61201 acatctcctc tggaaccacc aaaccacgag caacaatgac tgctggtgtc tcaggtagaa
    61261 acattttttt caaaacttca taacggctgt tggaaggcat gctgatcaga taagaccact
    61321 ccttcatccc caaaagttga atccgctctg gtgtatagta gtcaaaatag cctgtcattt
    61381 caagaccagg tcgcgtaata tccgctgtat tgatttcctt ttcaagcaac tctggttcac
    61441 catagacaat gtctagtcta agcttttcaa tcacttcttt tactaaaacc gacatcattt
    61501 cctccttcaa atgagttctt ctctctatta tatcaaattg taggaggaag tttcagattt
    61561 ttgcaggctt tggagtattt atttaaaaga aaaaggacta gatttctcta gcctttcatt
    61621 tcaattagaa ttttttacgt ttacgagcta cttctgattt acgtttacgt tttacagaag
    61681 gtttttcata gaattcacgt ttgcgtgttt cttgaagagt accagcttta gtaaccgcac
    61741 gtttgaaacg gcgaagtgcg tcgtcaagag attcattctt acgtactact gttttagaca
    61801 tttttttcac tcccttcaag ttcaatatct atttcattct acacgtaaaa ggaataattg
    61861 tcaagcaaaa atgcggttta attttgattt tttcttccat ttatacaaga gttgaaagcg
    61921 ttcaatagaa cattgctttt ttatttttcg agtaagctaa gcgcttcagc atctgcgatg
    61981 atggttacat cagggtgatt ttgaaggcta cttgcaggta ggttctcagt cactgggcca
    62041 gatactgttc cggcaatggc ttctgctttc gactcaccgt aagcaaaaag aataatagac
    62101 ttggcatcca aaatgttttt aatccccatt gaaatagctt gggttgggac gtcttcaatc
    62161 ttggcaaaga agcgtgcatt ggcttcgata gtagactggt caagttctac tagatgcgtt
    62221 tgactgtcaa atggagtacc aggctcatta aagccgatat gcccattgcg accgattccc
    62281 aagatttgga ggtcaactgg atggtcagcc aaaatttggt tgtagcgttc aacttcagct
    62341 tcagcattgt ccttaacacc acgaggcaag aaactttctt taaatggttt ttggttgaac
    62401 aagttttctt gcatgaagta acgataagat tgtggattgt ccccatcaag gcccacatac
    62461 tcatcaaggt tgacactggt tagatttgaa aaatcaaggt cactctcaac aatttccttg
    62521 taaaattcaa gtgggctact tcctgtcgca agtcctagag tttgagctcc attagccaat
    62581 ttttccttca aaatctcaaa agcaactttt ccaccttgaa cttggttttc aactttaata
    62641 actttcatct tttcatcctc catttctgtc tatatttatt atatggtata gaccaatttt
    62701 tgtcaagtga aaacgattta atttctaaaa aaagagcgtc caaacttgaa acgtgttata
    62761 atggatagga ttagaactta gaaagaatga acaaatatat gaatacagct gattttgatt
    62821 tccacttgcc agaggaattg attgcccaaa cgccccttga aaaacgtgat gcctccaaac
    62881 tcctcatcgt caaccgtgag acaggagaaa tgcaagataa acacttctac tctattattg
    62941 atatgctgga acctggtgat gcccttgtca tgaacgacac ccgagttctc cctgcccgcc
    63001 tctatggtca aaaagtggag acaggaggtc atgtggaact tctcctcctt aagaacacta
    63061 gtggagacga gtgggaagtt ctggctaaac ctgccaaacg cctcaaggtc ggtactcgta
    63121 tcagctttgg tgatggccgc ctcagcgctg tcgttacaga agaattgacc cacgggggac
    63181 gcattgtccg ctttgaatac caaggaattt tcctagaagt cttggaaagt ctgggagaaa
    63241 tgcctctgcc accttatatc cacgaaaaat tagatgaccg tgaacgttat caaaccgtct
    63301 acgccaagga aagcggctct gctgcagcac cgactgctgg tcttcacttc accaaagaac
    63361 tgctggcaga aatccaagct aagggtgttc atctagtcta tctgactctc catgtcggac
    63421 tcggaacctt tagacctgtt tctgtggata atctggacga acacgaaatg cactcagagt
    63481 tctatcaact ttctgaggaa gctgctgcca cccttcgctc tgtcaaagaa aatggtggtc
    63541 gcgtcatcgc tgtcggaacc acttctatcc gcaccttgga aactattggt tccaagtttg
    63601 atgggcaaat ccaagcagat tctggttgga ccaatatctt tatcaaacct gggtatgagt
    63661 ggaaggtcgt ggatgccttc tcaaccaact tccatctgcc aaaatcaact ctggtcatgt
    63721 tggtttctgc ctttgcaggc cgtgaattag tcttagatgc ctaccaccat gccatccaag
    63781 aacactaccg cttcttcagt tttggtgacg ccatgtttat ttattgagaa agaatttctc
    63841 taattcttct aataccaata aatcgctaag atattatttc aaagaacatc tacaattgaa
    63901 actctagcta gctgtagaag acgcctagta cattgaaatt aaaatgcttc cccctagctt
    63961 cgaaaatatt gccatagatt gcgttgactc tccaaattga ttcatctata ttttatttca
    64021 gcttcctata ttttcttcgc tgtttgtaaa tcaaaatgca agacacatga gtagcaccat
    64081 atttgttact cttatctgtc ctctcaagag actattatga gttatttcag aatcattcac
    64141 tactttgacc ctgactctcc ttagtctcaa aatcaaagac ttatactctt caaaaatctc
    64201 ttcaaaccgc gtcaacgtca ccttggatta tatatgtgac tgacttcgtc agttctatct
    64261 acaacctcaa agcagtactt tgagcaacct gcgactagtt ttctagtttg ctctttgatt
    64321 ttcattgagt attaaacaaa aagtgaacaa atctgaattc taatgtacag aagactaggc
    64381 ttgttcactt ttttatagtc gctataagat gaccttatct atagcttttt atatataatt
    64441 atatattcag acatactatt atcaattttg tcgcagggag gaatctgtta acgcacccat
    64501 tcaccattat cattgactct atagccatct atacttgtat tgaccgctaa ctcacccgat
    64561 gtatttacat aataccattt accaccaact tggaaccatt gattgacttt catagaaccg
    64621 ttgctgttga ggtagtacca tgaaccatta acttgtaccc aacctgttgc catggaacca
    64681 tcagtattat aaaaatacca cataccattt tcttgtttcc agcctgttgt tggagcaact
    64741 gctttagctg gttctactgc tacatctgtt ccttggttag atgtaacaga tacaggatac
    64801 gaaggaatag atgattgctc aggaacaaca actttttcag gttctctcgt ccctctcctt
    64861 atacgtcttt ttaccatctc tttagtaatt tgacgagaag tagtttcttc aattgttcca
    64921 tcacgttcat ctacagtata gattgtagta agagtaattt accaatttct cctacttctt
    64981 ctacttcttg acttttatca agagttgggc catcgagata ttctgtttcg attgaaattt
    65041 cttggacaag aacttggggc ttggttcctt ttttaacaac tcttgtttga gagtcttctt
    65101 tttgacttaa agtactctca gttacttgtc cactctttcc atctacatca taagttatcg
    65161 ttgtaactgt tttcccattc tttcctagag taatctcttg ctcctgtcct gcagaaaggt
    65221 cattgtctgc ttcatattta gtagcaaatg gaacaaaaac ttcttcaacc ttgcttttag
    65281 ctggaacttt gataactgta tccgtggctt cttttctatc aacagtaacc tgttcggtaa
    65341 catgaccagt ctctggatta acatcgtagg tccttgtcgt agttacatag ccatcctctc
    65401 catcaattgt aacaggattt tcactacggt cttttgtttc atctttttca taacgaattc
    65461 gcgtacttga aattttcttg gttactacct taggtttagt cgctactttt acaataatat
    65521 ccccattgtc agcgtcatca tactctattc cctcttcttt atctctagta tcatctctga
    65581 catattgaat cccatcagca gcatgaacaa aacttgtatt cagattcctc ctaaaaataa
    65641 agttagcccg attaccgcag aaccaaaaat ctttccgagt ttacgtattg catagcgctt
    65701 attagtatta gattttgcca ttacatccta cttctagtat agcatctttt ctatcaaacg
    65761 ttaaacaata tactttatat ataaaataga cttagaatga tatattgatt attgaactaa
    65821 cactttaact atatcgtaat caatctcata tataaaggat tgcagacatc ttatctaaat
    65881 acatgctaat atatttagat acaaacattc caacttgata attttcactc atctttcatc
    65941 attccttata caactatgca gtataaatag aat
//
LOCUS       DAVLBE010000005        62903 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.005, whole genome shotgun sequence.
ACCESSION   DAVLBE010000005 DAVLBE010000000
VERSION     DAVLBE010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 62903)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 62903)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..62903
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.005"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            352..1215
                     /locus_tag="VXB91_000304"
     CDS             352..1215
                     /locus_tag="VXB91_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEV0469817.1"
                     /translation="MIEKMELGEFYKELRLARKLKQSDVACDGLTASQLSKFELGQSM
                     LSADKLILAIQGINVTFDEFGHKLNNYQESPHMQIGRKVVDRFAHQDIAGLEQLLEEV
                     EQEQMAETYRRLNAIVIKDAIHSLDKSYPLAEEDSEFLTTYLYAIESWTWFELYLFCN
                     TLPFLSNQDLIFLSTSLLEKSKEFKELVHNRLYMKQGLLNIISELMERKLFSYIPIFE
                     AELESMLRPYDVFEKVLWQFLKKMSIFLQTKGSNQKEIEHFIQSLQVLENPQLIALFE
                     LRLQQYKKLID"
     gene            1501..1701
                     /locus_tag="VXB91_000305"
     CDS             1501..1701
                     /locus_tag="VXB91_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide pheromone VP1"
                     /protein_id="HEV0469818.1"
                     /translation="MLNLQFAETMELTEAELEIVYGGEFGNNAVIPAGAWGGFGTPWS
                     ITNFWKKNFNDRPDFDSDRRRY"
     gene            1768..2433
                     /locus_tag="VXB91_000306"
     CDS             1768..2433
                     /locus_tag="VXB91_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0469819.1"
                     /translation="MKKIISHRYFIIVFLLVIADQKFSVLVLRSDLVTGLSDFAYYLS
                     DMMLNFLVVLFALIAMIWSGKWQKINSRKFKGSYLFYSFLALLAFVVWNFVTFFLFPP
                     TRNEISYQHAAPTFTGATAFLMYFFYPVIAGPIFEEIIHRGLVMTALEKGKKWGLDVL
                     GSAILFGVSHISNHGWVLTDFVFYMGGGLIFAVLFRMTKSIYWPIGLHIVYNGIGQLL
                     MLL"
     gene            2505..3731
                     /locus_tag="VXB91_000307"
     CDS             2505..3731
                     /locus_tag="VXB91_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV0469820.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLA
                     ILLITISETLPQVLQIFLGVLADFQHHRVLKYTVISFTKFLLYSIVSLSLSGQSFSLF
                     LVTFICMINLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTISYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPVSTLFLRNQPFLNLQTGQSLALLSTFEL
                     SALIVGSLVSGYLQHTISIKTALYASLVIQLLLLVGFATVRFDWILIFSTLDAFFAGV
                     LSPRLQELVFKQIPEESMGAVQSSISAITVVLPSLFTISLVTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
     gene            complement(4084..4158)
                     /locus_tag="VXB91_000308"
                     /pseudo
     CDS             complement(4084..4158)
                     /locus_tag="VXB91_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829418.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            4229..4885
                     /locus_tag="VXB91_000309"
     CDS             4229..4885
                     /locus_tag="VXB91_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HEV0469821.1"
                     /translation="MPTALGYVSIGLACGIIGAPYVTPVEMGLMSLFVYAGSAQFAML
                     ALIVVQAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSLWHNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTALGDLLPNPEIFGLDFALVGMFIGI
                     FASQFQMMQRRISVRNLLIILAVVAVSFFLLLTVVSQSLAVLFATLLGCSMGMVLDGQ
                     "
     gene            4875..5084
                     /locus_tag="VXB91_000310"
     CDS             4875..5084
                     /locus_tag="VXB91_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HEV0469822.1"
                     /translation="MVSKYLLLAVIFSGLVTWIPRMIPFILVKYKGLPTIVERFLKFL
                     PVSIIFALILSRVVTGKVGNLPQIK"
     gene            5302..6132
                     /locus_tag="VXB91_000311"
     CDS             5302..6132
                     /locus_tag="VXB91_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0469823.1"
                     /translation="MKKIVKYSSLAALALVAAGVLAACSGGAKKEGQAASKKEIIVAT
                     NGSPRPFIYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            6286..7140
                     /locus_tag="VXB91_000312"
     CDS             6286..7140
                     /locus_tag="VXB91_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HEV0469824.1"
                     /translation="MKIKKWLGLAALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIADTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEESS
                     DGLDQPVW"
     gene            7240..8613
                     /locus_tag="VXB91_000313"
     CDS             7240..8613
                     /locus_tag="VXB91_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HEV0469825.1"
                     /translation="MVFPSEQEQIEKFEKDHVVQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLRGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEERMAFLKRFFFEPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYHTHIELVE
                     ELIRSYE"
     gene            8606..9667
                     /locus_tag="VXB91_000314"
     CDS             8606..9667
                     /locus_tag="VXB91_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HEV0469826.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSELSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSDPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGSSTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGGQ"
     gene            9669..10361
                     /locus_tag="VXB91_000315"
     CDS             9669..10361
                     /locus_tag="VXB91_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0469827.1"
                     /translation="MESLIQTYLPNVYKMGWSGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAIPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIIIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(10390..10959)
                     /locus_tag="VXB91_000316"
     CDS             complement(10390..10959)
                     /locus_tag="VXB91_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEV0469828.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIALFFLGTKHGAGSFLPGIICGLLADEVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVAPNPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            11094..11708
                     /locus_tag="VXB91_000317"
     CDS             11094..11708
                     /locus_tag="VXB91_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEV0469829.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLAGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFVSSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKILLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            11710..13362
                     /locus_tag="VXB91_000318"
     CDS             11710..13362
                     /locus_tag="VXB91_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV0469830.1"
                     /translation="MKQFWLHTLLRTYSSVMIIIIASFAILLSYADWDSREKEAQRVA
                     QRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQLERKASPY
                     ISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDFKPAGNSFA
                     IPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGHTPMAVTVTSPFDTEIFHIGETVDK
                     ESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLNLTLRQTFA
                     NYQKQVVDLVESIQVIAQGEEGRRIDISEKDQELLLIAETTNDMLDRLEKNIHDIYQL
                     ELSQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLRNNISDE
                     RETLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVENYFAHG
                     VDHRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQRYFEHQASYSDQ
                     RQSIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            13374..14660
                     /locus_tag="VXB91_000319"
     CDS             13374..14660
                     /locus_tag="VXB91_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0469831.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFTIPYYVLGQDWQIFISGQPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRVPITKQLFIQFVMDVF
                     HLFEHLKADDLTDIVKTIHAIQSFDELVSYIKETLISFFGQYRMNENVVSVLEVIGRD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            14712..15245
                     /locus_tag="VXB91_000320"
     CDS             14712..15245
                     /locus_tag="VXB91_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000729030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0469832.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRAAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKALAEEEETEELT"
     gene            15323..15793
                     /gene="nrdI"
                     /locus_tag="VXB91_000321"
     CDS             15323..15793
                     /gene="nrdI"
                     /locus_tag="VXB91_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEV0469833.1"
                     /translation="MKTISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHPYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(16086..17348)
                     /locus_tag="VXB91_000322"
     CDS             complement(16086..17348)
                     /locus_tag="VXB91_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HEV0469834.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDALFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIVIIKFFAGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
     gene            complement(17658..18116)
                     /locus_tag="VXB91_000323"
     CDS             complement(17658..18116)
                     /locus_tag="VXB91_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HEV0469835.1"
                     /translation="MKKQVFHDAAAGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWAAIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            complement(18113..18553)
                     /locus_tag="VXB91_000324"
     CDS             complement(18113..18553)
                     /locus_tag="VXB91_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0469836.1"
                     /translation="MKVELQISETYEEEKLIVQAPQETEKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPSNFIQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            18909..20858
                     /gene="mutL"
                     /locus_tag="VXB91_000325"
     CDS             18909..20858
                     /gene="mutL"
                     /locus_tag="VXB91_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HEV0469837.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKVQITDNGHGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVEQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(21183..21650)
                     /locus_tag="VXB91_000326"
     CDS             complement(21183..21650)
                     /locus_tag="VXB91_000326"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HEV0469838.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIEVAWVPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(21651..22856)
                     /locus_tag="VXB91_000327"
     CDS             complement(21651..22856)
                     /locus_tag="VXB91_000327"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HEV0469839.1"
                     /translation="MEYRKIQETLEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERNGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRTDDLIQFSKKHNIPLITIKELQEYRKVYDQLIERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKA
                     MKMIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(22876..23511)
                     /gene="ribE"
                     /locus_tag="VXB91_000328"
     CDS             complement(22876..23511)
                     /gene="ribE"
                     /locus_tag="VXB91_000328"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HEV0469840.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSINGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLKQTILKSKQVGSTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(23496..24596)
                     /gene="ribD"
                     /locus_tag="VXB91_000329"
     CDS             complement(23496..24596)
                     /gene="ribD"
                     /locus_tag="VXB91_000329"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HEV0469841.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAVIVKDNHIIGQGYHE
                     FFGGPHAERNALKNCRESPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
                     IATKTNQSKWITEEEARKHVHQLRHHVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(24731..24845)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            25002..25595
                     /gene="ruvA"
                     /locus_tag="VXB91_000330"
     CDS             25002..25595
                     /gene="ruvA"
                     /locus_tag="VXB91_000330"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HEV0469842.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQED
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDDLPAKVAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            25605..26168
                     /locus_tag="VXB91_000331"
     CDS             25605..26168
                     /locus_tag="VXB91_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HEV0469843.1"
                     /translation="MTKRCSWVKMTNPLYIAYHDEEWGQPLHDDQALFELLCMETYQA
                     GLSWETVLNKRQAFREAFHSYQIHSVAEMTETELEAMLENPAIIRNRAKLFATRANAQ
                     VLLQLQAEYGSFDAYLWSFVEGKIVVNDVPDYRQAPAKTPLSEKLAKDLKKRGFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWKGLK"
     gene            26165..26842
                     /locus_tag="VXB91_000332"
     CDS             26165..26842
                     /locus_tag="VXB91_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0469844.1"
                     /translation="MMSNKNKGILIFAILYTVLFVFDGVKLLASLMPSVIANYLVYVV
                     LALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVRL
                     DGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLPGLLSIILV
                     GLVFALTHMHSLALSEWIGAVGYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
     gene            complement(26979..28010)
                     /locus_tag="VXB91_000333"
     CDS             complement(26979..28010)
                     /locus_tag="VXB91_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HEV0469845.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKDLGLNPIFLPHS
                     LKGLDFIKDHPEARAEDLIHAFSDDSIDMILCAIGGDDTYRLLPYLFENDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIETGRIS
                     EIRPSDVWYEERTDFSPTALGTPRVSHTNTGFDLLQGSAQFEGKILGGCLESLYDIFD
                     NSRYADSTELCQKYKLFPDLSDWEGKILLLETSEEKPKPEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDETFHDDYKEALLDIIDSNIPIVYNLNVGHATPRAIVPFGVHAHVDAQE
                     QVILFDYNK"
     gene            complement(28265..28948)
                     /locus_tag="VXB91_000334"
     CDS             complement(28265..28948)
                     /locus_tag="VXB91_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HEV0469846.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGPDMDRSQRPPFWK
                     SVLVILTSMFLWLLVFFATSFLPASLNPVLDPLPLAIIGVALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(28960..29904)
                     /locus_tag="VXB91_000335"
     CDS             complement(28960..29904)
                     /locus_tag="VXB91_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEV0469847.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            30036..32867
                     /gene="uvrA"
                     /locus_tag="VXB91_000336"
     CDS             30036..32867
                     /gene="uvrA"
                     /locus_tag="VXB91_000336"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HEV0469848.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAINASSVEQIVDKVLELPERQRLQILAPVIRKKK
                     GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDDSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPDASKTLHEGALAPWNPISSNYYPNMLEQAMKVFGVAMDKP
                     FEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCQGYRLNDQALSVRVGGQQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVTGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDAGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            32860..33921
                     /locus_tag="VXB91_000337"
     CDS             32860..33921
                     /locus_tag="VXB91_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEV0469849.1"
                     /translation="MNKRVQAFLAKMQEKELDGIIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMNLTRIGFEDEISVSYY
                     HRMQAAFAGLNLLPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
     gene            34053..34451
                     /gene="spx"
                     /locus_tag="VXB91_000338"
     CDS             34053..34451
                     /gene="spx"
                     /locus_tag="VXB91_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HEV0469850.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
     gene            34517..35086
                     /locus_tag="VXB91_000339"
     CDS             34517..35086
                     /locus_tag="VXB91_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEV0469851.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGPATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLAIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLAGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSKYISDRLANGATEQ"
     gene            35173..35439
                     /locus_tag="VXB91_000340"
     CDS             35173..35439
                     /locus_tag="VXB91_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HEV0469852.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            35443..35862
                     /gene="ruvX"
                     /locus_tag="VXB91_000341"
     CDS             35443..35862
                     /gene="ruvX"
                     /locus_tag="VXB91_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HEV0469853.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPVDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            35878..36183
                     /locus_tag="VXB91_000342"
     CDS             35878..36183
                     /locus_tag="VXB91_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HEV0469854.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            36441..37691
                     /locus_tag="VXB91_000343"
     CDS             36441..37691
                     /locus_tag="VXB91_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEV0469855.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRMQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLTDQVKE
                     MEKTLLQTPAQLSFFELLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKAGKKAVIAKLPPEARLVCQKKAESLAVDLYQA
                     GQDFSVLNGDFSSSLLNLSQLNIGLEGAYQQENAALALQTFLLFMGERKEAIDEQAVR
                     KALEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGSLKRKD
                     YQGMLGYLTENLPQVELKMTGFDYQGSLDETDVTGYHVIPSYREFISSFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            37688..38230
                     /locus_tag="VXB91_000344"
     CDS             37688..38230
                     /locus_tag="VXB91_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin/fatty acid-binding family protein"
                     /protein_id="HEV0469856.1"
                     /translation="MTPFFELVILGELLVRENFSKLVAERKFIMKLKRFTLSLASLAS
                     FSLLVACSQRAQQVQQPVAQQVQQPAQQNTNTANAGGNQNQAAPVQNQPVAQPTDIDG
                     TYTGQDDGDRITLVVTGTTGTWTELESDGDQKVKQVTFDSANQRMIIGDDVKIYTVNG
                     NQIVVDDMDRDPSDQIVLTK"
     gene            38376..39908
                     /gene="cls"
                     /locus_tag="VXB91_000345"
     CDS             38376..39908
                     /gene="cls"
                     /locus_tag="VXB91_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HEV0469857.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGVNLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIREIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            40166..41704
                     /locus_tag="VXB91_000346"
     CDS             40166..41704
                     /locus_tag="VXB91_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HEV0469858.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWGLHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     FFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVSLGLLVFNLG
                     HRRFAHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLLVFGFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILS
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVVVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            41824..44031
                     /gene="nrdD"
                     /locus_tag="VXB91_000347"
     CDS             41824..44031
                     /gene="nrdD"
                     /locus_tag="VXB91_000347"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HEV0469859.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKRLNDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKREDYAWK
                     KTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHRLGKEESVDQLFKNRRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTN"
     gene            44043..44183
                     /locus_tag="VXB91_000348"
     CDS             44043..44183
                     /locus_tag="VXB91_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0469860.1"
                     /translation="MGKYQLDDKGRAQVTRYHEKHSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            44227..44733
                     /locus_tag="VXB91_000349"
     CDS             44227..44733
                     /locus_tag="VXB91_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0469861.1"
                     /translation="MELRRPRLADKKAVLDMMTEFEKFQSPHDGGFWDTENFVYEDWL
                     ESNQEQEMGINLPEGWVPAIQLVAFSEKGQAVGFLNLRLRLSNFLLEEGGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNPASRAVIIANGGIFEDARNGVER
                     YWIEVANE"
     gene            44726..45316
                     /gene="nrdG"
                     /locus_tag="VXB91_000350"
     CDS             44726..45316
                     /gene="nrdG"
                     /locus_tag="VXB91_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HEV0469862.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVSGCMF
                     HCEGCYNVATWSFNAGIPYTAELEEQIMADLAQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELPDKDIWSWTGYTWEEMMLETPDKLEFLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKESYEQVKRE"
     gene            45324..45941
                     /locus_tag="VXB91_000351"
     CDS             45324..45941
                     /locus_tag="VXB91_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
                     /protein_id="HEV0469863.1"
                     /translation="MKKKDLVDQLVSEIETGKVRTLGIYGHGASGKSTFAQELYQALD
                     STTVNLLETDPYITSGRYLVVPKDAPNQKVTASLPVAHELESLQRDILALQAGMDVLT
                     IEEPWKASEVLSGAKPILIVEGMSVGFLPKELFEKTICFYTDEETELKRRLARDTTVR
                     NRYASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
     gene            46207..46515
                     /gene="rpsJ"
                     /locus_tag="VXB91_000352"
     CDS             46207..46515
                     /gene="rpsJ"
                     /locus_tag="VXB91_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HEV0469864.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            46732..47358
                     /gene="rplC"
                     /locus_tag="VXB91_000353"
     CDS             46732..47358
                     /gene="rplC"
                     /locus_tag="VXB91_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HEV0469865.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            47383..48006
                     /gene="rplD"
                     /locus_tag="VXB91_000354"
     CDS             47383..48006
                     /gene="rplD"
                     /locus_tag="VXB91_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HEV0469866.1"
                     /translation="MANVTLFDQTGKEAGQVVLSDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            48006..48302
                     /locus_tag="VXB91_000355"
     CDS             48006..48302
                     /locus_tag="VXB91_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HEV0469867.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            48320..49153
                     /gene="rplB"
                     /locus_tag="VXB91_000356"
     CDS             48320..49153
                     /gene="rplB"
                     /locus_tag="VXB91_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HEV0469868.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            49257..49538
                     /gene="rpsS"
                     /locus_tag="VXB91_000357"
     CDS             49257..49538
                     /gene="rpsS"
                     /locus_tag="VXB91_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HEV0469869.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            49550..49894
                     /gene="rplV"
                     /locus_tag="VXB91_000358"
     CDS             49550..49894
                     /gene="rplV"
                     /locus_tag="VXB91_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HEV0469870.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            49907..50560
                     /gene="rpsC"
                     /locus_tag="VXB91_000359"
     CDS             49907..50560
                     /gene="rpsC"
                     /locus_tag="VXB91_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HEV0469871.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            50564..50977
                     /gene="rplP"
                     /locus_tag="VXB91_000360"
     CDS             50564..50977
                     /gene="rplP"
                     /locus_tag="VXB91_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HEV0469872.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            50987..51193
                     /locus_tag="VXB91_000361"
     CDS             50987..51193
                     /locus_tag="VXB91_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HEV0469873.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            51218..51478
                     /gene="rpsQ"
                     /locus_tag="VXB91_000362"
     CDS             51218..51478
                     /gene="rpsQ"
                     /locus_tag="VXB91_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HEV0469874.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            51504..51872
                     /gene="rplN"
                     /locus_tag="VXB91_000363"
     CDS             51504..51872
                     /gene="rplN"
                     /locus_tag="VXB91_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HEV0469875.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            51950..52255
                     /gene="rplX"
                     /locus_tag="VXB91_000364"
     CDS             51950..52255
                     /gene="rplX"
                     /locus_tag="VXB91_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HEV0469876.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            52279..52821
                     /gene="rplE"
                     /locus_tag="VXB91_000365"
     CDS             52279..52821
                     /gene="rplE"
                     /locus_tag="VXB91_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HEV0469877.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            52839..53108
                     /gene="rpsN"
                     /locus_tag="VXB91_000366"
     CDS             52839..53108
                     /gene="rpsN"
                     /locus_tag="VXB91_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HEV0469878.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            53393..53791
                     /gene="rpsH"
                     /locus_tag="VXB91_000367"
     CDS             53393..53791
                     /gene="rpsH"
                     /locus_tag="VXB91_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HEV0469879.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            53983..54519
                     /gene="rplF"
                     /locus_tag="VXB91_000368"
     CDS             53983..54519
                     /gene="rplF"
                     /locus_tag="VXB91_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HEV0469880.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEVTLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            54603..54959
                     /gene="rplR"
                     /locus_tag="VXB91_000369"
     CDS             54603..54959
                     /gene="rplR"
                     /locus_tag="VXB91_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HEV0469881.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            54977..55471
                     /gene="rpsE"
                     /locus_tag="VXB91_000370"
     CDS             54977..55471
                     /gene="rpsE"
                     /locus_tag="VXB91_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HEV0469882.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            55443..55667
                     /gene="rpmD"
                     /locus_tag="VXB91_000371"
     CDS             55443..55667
                     /gene="rpmD"
                     /locus_tag="VXB91_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HEV0469883.1"
                     /translation="MVFQFLIWHKKGDKMAQIKITLTKSPIGRIPSQRKTVVALGLGK
                     LNSSVIKEDNAAIRGMITAVSHLVTVEEVN"
     gene            55812..56252
                     /gene="rplO"
                     /locus_tag="VXB91_000372"
     CDS             55812..56252
                     /gene="rplO"
                     /locus_tag="VXB91_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HEV0469884.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            56265..57575
                     /gene="secY"
                     /locus_tag="VXB91_000373"
     CDS             56265..57575
                     /gene="secY"
                     /locus_tag="VXB91_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HEV0469885.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            57726..58364
                     /locus_tag="VXB91_000374"
     CDS             57726..58364
                     /locus_tag="VXB91_000374"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HEV0469886.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLA
                     ELGIELEGIINIEVNPDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEKVLTNLK"
     gene            58481..58699
                     /gene="infA"
                     /locus_tag="VXB91_000375"
     CDS             58481..58699
                     /gene="infA"
                     /locus_tag="VXB91_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HEV0469887.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            58724..58840
                     /gene="rpmJ"
                     /locus_tag="VXB91_000376"
     CDS             58724..58840
                     /gene="rpmJ"
                     /locus_tag="VXB91_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HEV0469888.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            58858..59223
                     /gene="rpsM"
                     /locus_tag="VXB91_000377"
     CDS             58858..59223
                     /gene="rpsM"
                     /locus_tag="VXB91_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HEV0469889.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            59241..59624
                     /gene="rpsK"
                     /locus_tag="VXB91_000378"
     CDS             59241..59624
                     /gene="rpsK"
                     /locus_tag="VXB91_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HEV0469890.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            59667..60602
                     /locus_tag="VXB91_000379"
     CDS             59667..60602
                     /locus_tag="VXB91_000379"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HEV0469891.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            60614..61000
                     /gene="rplQ"
                     /locus_tag="VXB91_000380"
     CDS             60614..61000
                     /gene="rplQ"
                     /locus_tag="VXB91_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HEV0469892.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            61265..61531
                     /locus_tag="VXB91_000381"
     CDS             61265..61531
                     /locus_tag="VXB91_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HEV0469893.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAVVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            61541..62878
                     /locus_tag="VXB91_000382"
     CDS             61541..62878
                     /locus_tag="VXB91_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HEV0469894.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPDINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALTETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGAAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     VGDSVARVLEEMGLETVGTHGTTAALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGREGDMIEFGGLLGTAPVMKVNGASSVDFISRGGQIPAPIHSFKN"
BASE COUNT        18733 a        11869 c        13824 g        18477 t
ORIGIN      
        1 aaatgttaaa ttttcacatt ttcatagtat actgtttaat agaaagtagg ttctttgtaa
       61 ccgctccatt ataaaatcct ttcactcttc cggtatacta ttaggaaaaa cataactgga
      121 ggatattttg agctcacacc tcatcgttcc agtggctgtt ccccaagctc gtgtactgcc
      181 caaaaaagtt agacattcta tttagaacga ggattgagtt ctgtattgta caaggctcgg
      241 tccttttaga gtcagcttaa ggctggcttt tttatttttt ctaactatca gaatattttg
      301 acaaatgaac acaaataatg atataatatg caaaagctag gaggtggtag gatgattgaa
      361 aaaatggaat tgggggaatt ttacaaggaa ttacgtttgg cgagaaagct caagcagtca
      421 gatgtggctt gtgacgggct aacagcttct cagttgtcca agtttgagct agggcagtcc
      481 atgttgtctg ctgataagct catattagcc atccaaggga tcaatgtgac ctttgatgag
      541 tttgggcaca agctcaacaa ctatcaagaa tctccacata tgcagattgg tagaaaggtt
      601 gtggatcgct ttgctcatca agatatagct ggcttagagc aactgttgga ggaagtcgag
      661 caagaacaga tggcagagac ttatcgtcgt ttgaatgcta ttgtaatcaa agatgccatc
      721 cactcactag ataaaagcta cccactagca gaggaggata gcgagttttt gaccacctat
      781 ctctatgcta tcgagtcttg gacctggttt gaactctatc tcttttgcaa tactctgccc
      841 ttcttgagca atcaagatct gatcttttta tcaacctcct tactcgaaaa atccaaagaa
      901 tttaaagagt tagtacacaa tcgattgtat atgaagcaag gactcttaaa tatcatctca
      961 gagctcatgg agcgcaaact tttttcttat atcccaatct ttgaagccga gctggagagt
     1021 atgctccgtc catacgatgt ttttgagaaa gtgttgtggc agtttttaaa gaagatgagc
     1081 attttccttc aaactaaggg aagcaatcaa aaagagattg aacactttat ccaatctctg
     1141 caagtattag aaaatccaca attaatagcc ctttttgaat tgcgtttgca gcaatacaaa
     1201 aagcttatcg attagttaga aatggcaaaa taataataat ctcagcaacg attttcaata
     1261 atgttaaaat ttgtttcttc atatttctcc actcctcatt agtagtaact ttattatacc
     1321 agagaagtaa tcaaattcac caaaatcgca aatctgaaat ttctataaga aaaaatatca
     1381 aatatgcgat tttctaaaat aagccaattt tcgtgttata ctgtacttgt aaagcacttg
     1441 aagcaaatcc taggtcacag aagtggttta caaatgaaga taattgaagg agtgtaaaag
     1501 atgttaaatt tacaatttgc agaaacaatg gaattgacag aagctgagtt ggagatagtt
     1561 tatggagggg aatttgggaa taatgctgtt atcccagccg gtgcttgggg agggttcggg
     1621 acaccttggt caatcactaa tttctggaag aaaaatttta acgatagacc tgactttgat
     1681 tctgaccgcc gtcgttatta atatccaaag cccttgcctt ttcttgggta ggggctgtct
     1741 ttatttcata gtataggagg aaatagaatg aaaaagataa tctcacaccg ctactttatt
     1801 atagtttttc tactagttat tgctgaccag aagttcagtg ttctagtttt acgcagcgac
     1861 cttgttactg ggctatctga ctttgcctat tatctgtcgg atatgatgtt gaattttctt
     1921 gtggttttat ttgctcttat tgctatgatt tggtcgggga aatggcagaa aatcaatagt
     1981 agaaagttta aaggatccta tcttttctat tccttcctag ctctgcttgc ttttgttgtt
     2041 tggaatttcg ttaccttttt tcttttccca cctactcgaa atgaaatttc ttatcaacat
     2101 gctgctccga cttttacagg ggctacagca tttttgatgt attttttcta tcctgtgatt
     2161 gcaggtccca tttttgaaga gataatccat cggggattgg tgatgacagc tctggaaaaa
     2221 ggaaagaaat gggggctaga tgtacttggc tctgctattt tatttggggt ctcgcacatt
     2281 agtaatcacg gttgggtctt gacagacttt gtcttctata tgggtggagg tcttatattt
     2341 gcagtcttat ttagaatgac aaagtcaatt tattggccta ttggactgca tatagtctac
     2401 aatggtattg gtcagctttt gatgttactg taattttggt tgttagtagt atcgcggtct
     2461 attcttgggg aaagattccc atttgaactt aagaaggagt tgtaatgaaa gtatttcttc
     2521 aaaatagaga ttttaggcaa ttaactatca accagtggat ttcaacgctt ggggatacga
     2581 ttttttatct ggccttcctg aattatgtgg cagatgcgtc ttttgcccct ttggcgattt
     2641 tacttatcac gatttcagaa acccttcccc aagttctaca aatctttctg ggagttttgg
     2701 cggattttca acatcatcgt gtcttgaaat acacagtcat tagttttaca aaatttttgc
     2761 tttactctat agtgtcccta tcgctttcag ggcagtcttt ttccttgttt ctagtaacct
     2821 ttatttgtat gattaacctc ttgtctgaca cattgagtta tttttcaggc gccatgctca
     2881 ctccgatttt cattagaatt attgggcaag atcatctggc agaagctatt ggatttaaac
     2941 agtcaactgt tagtttagtg aaaacaatca gtaatatcct aggaggagtc ttactaggta
     3001 ttctatccat ccagtttatt tccttactga acgctcttac ctttttaatc gcatttttag
     3061 gtatcctctt cataaaaact gacctcttga aagtagaaaa aacgattagc tatcaagaag
     3121 gactctctgt aaaatccttt tgccagcatt tgctccaatc atcgaaattg atatggaata
     3181 tgaataaggt gctcttggtt ttgtttatta tctctactag tcaagcagtg ataaatgtta
     3241 cagttcctgt ctctactcta tttttgagga atcaaccctt tttgaattta caaacaggtc
     3301 aatctcttgc cttgctatcc acttttgaac tgtcagccct gattgtcgga agccttgtaa
     3361 gtggctatct gcaacatacc atttccataa aaacagctct ctatgcctca cttgtcatcc
     3421 agttgcttct tctagtagga tttgccacag ttcgttttga ctggattctc atctttagta
     3481 ccttggatgc ctttttcgca ggtgttctct ctcctagatt gcaagaactc gtctttaaac
     3541 aaatacctga ggagtcaatg ggagcagttc aatcttctat cagtgccatt acggttgttt
     3601 tacctagctt atttacaata tctttggtaa ccattgctac tagctttgga actctggcag
     3661 ttagctttgt tttattgcta tttcttctag ttgcctttgt tatgcttctg aatattcgtg
     3721 aaagtattta gtggagaatt tctataatat atgtttgaga ctggattgcc agtcttttta
     3781 tgatggtcaa aatcaacaga ctttttctct tttctgaatg tgttatagta gactgaatct
     3841 aaaatagtac gaaacaattg ctaaaacatt tatagaaatt aattttactt tcccaatcga
     3901 tttgttctca tcttatttca atctgctata taatagtcca tgctgtggct ggattctttt
     3961 cagcctactt atactcttcg aaactctctt caaaccacgt cagcttcacc ttgccgtata
     4021 tgtgttactg acttcgtcag ttctatccac aacctcaaaa cagtgttttg agctgacttc
     4081 atcagttcta tctgcaacct caaaacagtg ttttgagcaa cctgcggcta gtttcctagt
     4141 ttgctctttg attttcattg agtattatta agacaatatg aggagaaaga tgaaagaaaa
     4201 aggattttag gagggggcgc aggcagccat gccaacggct cttggctatg tcagtatcgg
     4261 cctggcctgt ggaattatcg gtgcgcccta tgtgacacct gttgagatgg gcttgatgag
     4321 tctctttgtt tatgctggga gtgcccagtt tgccatgttg gcactgattg tggttcaagc
     4381 tcctgtggca gctattgcta tgacggtttt tctaatcaat ttgcgtctct ttttgttgag
     4441 cttacacgca tcgacttatt tccgtcatac cagtctttgg cacaatatcg gtatgtctag
     4501 tatcttgaca gatgagacct atggcgtttt gatgggcgaa ttagcccata cagataaggt
     4561 caatccgatg tggatgcacg ggaacaatct caacagctat gtggcttggt ttgtgggaac
     4621 agtggtcgga acggctctag gtgacctgtt gccaaatcca gaaatctttg gtttagattt
     4681 tgccctggtt gggatgttta tcgggatttt tgcttcgcaa ttccagatga tgcaaagacg
     4741 gatttctgtc cgcaatctgc tcattatctt agcagttgtt gcagtgtcct tctttttact
     4801 tttgacagtg gtgtctcagt cactagctgt tctgtttgcg acgctacttg gttgtagcat
     4861 ggggatggtt ttagatggtc agtaagtatc ttttattagc agttattttc tctggtcttg
     4921 tgacctggat tccccgtatg attcccttca tcttggtcaa gtataagggc ctgcctacga
     4981 ttgttgagcg ttttttgaag tttttgcctg tttccattat ctttgccttg attctttcaa
     5041 gagtagtgac aggtaaggtt gggaaccttc ctcaaatcaa atgactggac ttcttagcag
     5101 tctttccaac agcttgggta gcttttcgct accgcaatct agtcggtacg gttctctttg
     5161 gagtagtctt gattgccgtc ttgcgtttgg tcttttaaat aagtcataaa gaaaacttat
     5221 cacagagata gatatcatat aatggcgtaa ttactttttt tctgataaga ttataaggta
     5281 ttctattttg gaggaaatga catgaaaaaa atcgttaaat actcatctct tgcagccctt
     5341 gctcttgttg ctgcaggtgt gcttgcggct tgctcaggtg gtgctaagaa agaaggacaa
     5401 gcagctagca agaaagaaat catcgttgca accaatggat caccaaggcc atttatctat
     5461 gaagaaaatg gcgaattgac tggttacgag attgaagtcg ttcgcgctat ctttaaagat
     5521 tctgacaaat atgatgtcaa gtttgaaaag acagaatggt caggtgtctt tgctggtctt
     5581 gacgctgacc gttacaatat ggctgtcaac aatcttagct acactaaaga acgtgcggag
     5641 aaatacctct atgccgcacc aattgcccaa aatcctaatg tccttgtcgt gaagaaagat
     5701 gactctagta tcaagtctct cgatgatatc ggtggaaaat cgacggaagt cgttcaagcc
     5761 actacatcag ctaagcagtt agaagcatac aacgctgaac acacggacaa cccaactatc
     5821 cttaactata ctaaggcaga tttccaacaa atcatggtac gtttgagcga tggacaattt
     5881 gactataaga tttttgataa aatcggtgtt gaaacagtga tcaagaacca aggtttggac
     5941 aacttgaaag ttatcgaact tccaagcgac caacaaccgt acgtttaccc acttcttgct
     6001 cagggtcaag atgagttgaa atcgtttgta gacaaacgca tcaaagaact ttataaagat
     6061 ggaactcttg aaaaattgtc taaacaattc ttcggagaca cttatctacc ggcagaagct
     6121 gatattaaat aatttcttga aatcatccat tctgagtaag atgggtggtt tctcagtttt
     6181 tagggatata gttttaaact atatatctga ctatctaata acaatttgtg aaatcaaaca
     6241 aattgtgaga tactagtacg gtattatttt taaggagaaa gaatcatgaa aatcaaaaaa
     6301 tggcttggtc tagcagccct tgctacagtc gcaggtttgg ctcttgcagc ttgcggaaac
     6361 tcagaaaaga aagcagacaa tgcaacaact atcaaaatcg caactgttaa ccgtagcggt
     6421 tctgaagaaa aacgttggga caaaatccaa gaattggtta aaaaagacgg aattaccttg
     6481 gaatttacag agttcacaga ctactcacaa ccaaacaaag caactgctga tggcgaagta
     6541 gatttgaacg ctttccaaca ctataacttc ttgaataact ggaacaaaga aaacggaaaa
     6601 gatcttgtag cgattgcaga tacttacatc tctccaatcc gcctttactc aggtttgaat
     6661 ggaagtgcca acaagtacac taaagtagaa gacatcccag caaacggaga aatcgctgta
     6721 ccaaatgacg ctacaaacga aagccgtgcg ctttacttgc ttcaatcagc tggcttgatt
     6781 aaattggatg tttctggaac tgctcttgca acagttgcca acatcaaaga aaatccaaag
     6841 aacttgaaaa tcactgaatt ggacgctagc caaacagctc gttcattgtc atcagttgac
     6901 gctgccgttg taaacaatac cttcgttaca gaagcaaaat tggactacaa gaaagcactt
     6961 ttcaaagaac aagctgatga aaactcaaaa caatggtaca acatcattgt tgcgaaaaaa
     7021 gattgggaaa catcacctaa ggctgatgct atcaagaaag taatcgcagc ttaccacaca
     7081 gatgacgtga aaaaagttat cgaagaatca tcagatggtt tggatcaacc agtttggtaa
     7141 taagaaacag ggaggtggga gagaaaattc cacctcttgc ttttgtatag agtatagatt
     7201 gtaaagaaga ctattcgttc atagaaaggt agagagaata tggtttttcc tagcgaacaa
     7261 gaacagattg aaaaatttga aaaggatcat gtagtccaac attattttga ggttttgcgt
     7321 accttgattt ctaagaaatc agtctttgcc cagcaggttg gactcaagga agtcgcaaat
     7381 tatctgggtg agattttcaa gcgtgttgga gctgaagtgg agattgatga gagctataca
     7441 gcgccctttg tcatggcaca tttcaagagt tcgcgtccag atgccaagac cttgattttc
     7501 tataaccact atgacactgt gccagcggat ggggatcagg tctggacaga ggatcctttt
     7561 acgctttcgg tccgcaatgg cttcatgtat gggcgtgggg ttgatgacga caagggtcat
     7621 atcacagctc gcttgagtgc tttgagaaaa tatatgcagc accatgatga tttacctgtc
     7681 aatatcagct ttatcatgga gggagcggag gaatcggctt caacagacct agataagtat
     7741 ttggaaaagc atgcagacaa actccgtggg gcggatttgt tggtctggga acaagggacc
     7801 aaaaatgcct tggagcagct ggaaatttct ggtggcaata aggggattgt gacctttgat
     7861 gccaaggtaa aaagcgctga tgtggatatc cactcgagtt atggtggtgt tgtggaatca
     7921 gctccttggt atctcctcca agccttacag tctcttcgtg ctgcggatgg ccgtatcttg
     7981 gttgaaggct tgtacgaaga agtacaagag cccaatgaac gagaaatggc cttgctagaa
     8041 acttatggtc aacgaaaccc agaggaagtt agtcggattt atggattgga gttgcctctc
     8101 ttacaggagg agcggatggc ctttctaaaa cgtttctttt tcgagccagc gcttaatatc
     8161 gaaggaatcc agtctggtta tcaaggtcag ggtgttaaga ctattttacc tgcagaagcc
     8221 agtgccaagc tagaggttcg tctggttccg ggcctagaac cgcatgatgt tctggaaaaa
     8281 attcggaaac agctagacaa aaatggcttt gataaggtag aattatacta taccttggga
     8341 gagatgagct atcgaagcga tatgagcgca ccagccattc tcaatgtgat cgagttggcc
     8401 aagaaattct atccacaggg cgtttcagtc ttgccgacga cagcggggac aggacctatg
     8461 catacggtct ttgatgccct agaggtacca atggttgcat tcggtctagg aaatgccaat
     8521 agccgagacc acggtggaga tgaaaatgtg cgaatcgctg attatcacac ccatatcgaa
     8581 ttagtagagg agctgattag aagctatgag tagagatatt atcaagttag atcagatcga
     8641 tgtgactttt caccaaaaga agagaaccat tacagcggtt aaggatgtga ccattcacat
     8701 ccaagaaggg gatatctacg gaatcgttgg atattctgga gcaggaaaat caacccttgt
     8761 acgggtgatt aatctcttgc aaaaaccatc tgcagggaaa attaccattg acgacgatgt
     8821 gatttttgac ggcaaggtga ccttgacggc agagcagttg cgtcgtaaac gtcaagatat
     8881 cggaatgatt ttccagcatt ttaacctgat gagccaaaag acagcagagg agaatgtagc
     8941 ctttgccctt aaacactctg aactcagcaa ggaagaaaag aaggctaaag tagctaagtt
     9001 gttggacttg gttggtttgg cagatcgtgc tgaaaactac ccttcacaac tatctggagg
     9061 gcaaaaacag cgtgtggcaa ttgcgcgtgc cttggccaat gatccaaaaa tcttgatttc
     9121 agacgagtca acttctgccc ttgatccgaa gacaaccaag cagattttgg ccttgttgca
     9181 agatttgaac caaaaattag gcttgactgt tgtcttgatt acgcatgaaa tgcagattgt
     9241 caaagacatt gccaaccgtg tggcggttat gcaggatggg catttgattg aagagggtag
     9301 tgtgcttgaa atcttctcag accctaaaca acctttgact caagacttta tctcaacagc
     9361 tacaggtatt gacgaagcca tggtcaaaat cgagaagcaa gaaatcgtgg aacacttgtc
     9421 tgaaaacagt ctcttggtgc aactcaagta cgctggatct tcaacagacg agccactttt
     9481 gaatgaattg tacaagcatt atcaagtaat ggctaatatt ctctatggga atatcgaaat
     9541 cctcgatggt actcctgttg gagaattggt ggtggtcttg tcaggtgaaa aagcagcgtt
     9601 ggcaggtgcc caagaagcca ttcgtcaagc aggcgtacag ttaaaagtat tgaagggagg
     9661 acagtaagat ggaatcattg attcaaacct atttgccaaa tgtctataag atgggttggt
     9721 ctggtcaggc aggctgggga acagctatct acctaaccct ctatatgaca gttctttcct
     9781 tcattatcgg aggcttcttg gggctagtgg caggtctctt tctcgtcttg acagcgccag
     9841 gtggtgtctt ggagaataaa gtcgtattct ggattttaga caaaattacc tcaatttttc
     9901 gtgcgattcc ctttatcatc ctcttggcaa tcttgtcacc actttctcac ttgattgtta
     9961 aaacaagtat cgggccaaat gcagcccttg tcccactttc ttttgcagtc tttgccttct
    10021 ttgcccgtca ggtgcaggtt gtcttggctg aattggatgg cggtgtcatt gaggcggctc
    10081 aagcgagcgg agcgactttc tgggacatcg tgggtgttta cctatcagaa ggtcttccag
    10141 atttgatccg tgtgacgact gtgaccttga tttcccttgt tggggaaaca gctatggccg
    10201 gtgcggttgg agctggtggt atcggtaacg tagccatcgc ttatggattt aaccgctaca
    10261 atcacgatgt gaccatcttg gcaaccatta ttatcatttt gattatcttt gcaatccaat
    10321 tcttgggaga tttcttgact aagaaattga gtcataaata aaaagagccg cgtggctctt
    10381 tttaactgat cagattttct gtgcaaattt tttactcaag gcttgtccaa tcaaggcacc
    10441 cactagggct ccgatgacaa tacttgcgat aaatagaagg acagttccag ggtttggagc
    10501 gaccatgata cggtcgatat attcttggga ttttcctctt gccagaagag tagccatata
    10561 ggctttgggc gcaatccaca taagcaagat tggtcctgtt gtactaaagg cgaaaataat
    10621 gaaagaaagg aagttctttg ttttgtcctt gtattttcct aaatgagcta cttcatctgc
    10681 taggaggcca cagataattc caggaaggaa ggaaccagca ccgtgtttag ttcccaagaa
    10741 aaagagggca atgacaaggc cgatagtggt aatggctcca aagcgcggaa cttttgcgac
    10801 taggatcata tagacgctac cgccgacaag ggcagtaaag gcaggcgcat aaaacatgtt
    10861 tccagtttgg tcaaagagat tgcccaaaag gacaccaatc cccatgcaga ggaagtaaag
    10921 aactgcaaaa agcagtgtag ttaagataga tttcttcatg aattgtctcc tgataatttt
    10981 ttcacaattc tcattgtacc acggtttggt gggattgtaa atggatacta gaagtttttg
    11041 aaaacgcttg aaatatgata taatggtttc atagttattt ttaggggaat atcatgggta
    11101 gatttttaga ctttgtcttt aatcgtttct ttttagggat gattgcgaca gccttctttt
    11161 ggctattaac tttagcagga gggattatcc ttggtctagc gccggctagt gccaccttga
    11221 tgagcttata tgcagaacat ggttatagct ttcgggaata cagtttgaag gaggcttggt
    11281 ctctttacaa gcaaaatttt gtctcaagca acctgatttt ctatagcttt ttaggtgtgg
    11341 gtctagtttt gacctatggt ttgtatctct tggtgcaatt gcctcatcag accattgttc
    11401 atttgattgc gacccttttg aatgtcctag tagttgccct gatctttttg gcttatacag
    11461 tatctttaaa attacaagtt tattttgcct tgtcctatcg aaatagtctc aaattatcct
    11521 tgattggcat ctttatgagt ctagcagctg tggccaagat tctccttggg actgtgctac
    11581 ttgtagcaat tggttactat atgcctgccc tgctattttt tgtaggaatt gggatgtggc
    11641 atttctttat cagtgatatg ttggaacctg tctatgaaat catccatgaa aaattggcga
    11701 caaaatagaa tgaagcagtt ttggctacat acgcttctaa gaacctatag ttcagtgatg
    11761 atcattatca ttgcgagttt tgcaatctta ctctcttacg ctgactggga ttcacgtgaa
    11821 aaggaagccc agagagtagc ccagcgtgta actgctagaa cagtgagtga aattgaatat
    11881 taccatagag agtcaaccca gatagctcag gctttagttg aaaaccaagc tcgtattgag
    11941 ggaatctata aatactttag tcttagcatg ccagactatt tttactggca attagagcgg
    12001 aaagcttcgc cttatatatc agtctctctg tatgaaaatg ttgatgacct ctatgttcga
    12061 aatgattttg taactggagt ggccattgct tttcaagatt acaaggaagt ctatgtttct
    12121 actaaagaca aacgtagtgg agaaaaaatc agggctgagg atttcaaacc agcaggaaat
    12181 agttttgcca ttccggtgtc agatccagtg tcagatcaag atttaggagt gatttacatc
    12241 tccttggatc ctgctgtttt ataccatgcc attgataata ctagaggtca tactccgatg
    12301 gcagtaacag tgacctcacc ttttgatacg gagatttttc atattggtga gacagttgat
    12361 aaggagagtg aaaattggct agttggctta acttctcatg gatatcaggt tcaggtggca
    12421 gttcctaaaa actttgtttt acaaggaaca gtgactagct ctgctttgat tgtgggtttg
    12481 agccttctct ttattgtcat tctttatctg aatctgactt tgaggcagac ttttgctaat
    12541 taccaaaagc aggtagtgga tttagtagaa tccattcaag tcattgctca aggcgaagag
    12601 gggcgtcgga ttgacatttc cgagaaagat caggaattac tcctaatcgc ggagacgacc
    12661 aatgatatgt tggatcgatt ggaaaagaat atccatgata tttaccagtt agagcttagt
    12721 caaaaagatg ccaatatgcg agccttgcag gcgcaaatca atcctcattt tatgtataat
    12781 acgctggagt tcttgcgcat gtatgcagtt atgcagagtc aagatgagtt ggcagatatc
    12841 atttatgaat tcagtagtct cttgcgtaac aatatttccg acgaaagaga gaccctcctc
    12901 aaacaggaat tagaattttg ccgtaaatac agctatctct gcatggttcg ctatcccaag
    12961 tccattgcct atggtttcaa gatagatcca gagttagaga atatgaagat tcccaagttt
    13021 accttgcaac cgctggtaga aaactatttc gcgcatggtg ttgaccacag gcggacagat
    13081 aatgtgatta gcatcaaggc tcttaaacag gatggttttg tggaaatttt ggtggtcgat
    13141 aatggtagag gaatgtcggc tgaaaagttg gcaaatatcc gagaaaaatt aagtcagaga
    13201 tattttgaac accaagccag ctacagtgat caaaggcagt ctatcgggat tgtcaatgta
    13261 cacgagcgtt ttgtgctcta ttttggagac cgctatgcca ttactataga gtctgcagag
    13321 caagccggtg ttcagtatcg tattacaatt caagatgagt agaaagggag aaaatgtata
    13381 aagtattatt agtagatgat gagtacatgg tgacagaagg tctgaagcgt ttgattccct
    13441 ttgataagtg ggatatggag gttgtcgcaa cagccagtca tgccgatgaa gctctagaat
    13501 atgttcagga aaatcctgtc gatgtcatca tttccgatgt caatatgcca gacaaaacag
    13561 ggcttgatat gattcgggag atgaaagaga tcttaccaga tgctgcctat atcctgctct
    13621 caggttatca ggagtttgat tatgtaaaaa gagcaatgaa ccttagtgtg gtggactatt
    13681 tggtcaagcc tgttgataag gtagagctgg gaaatctgct ggagaagatt gcaggtcagc
    13741 tcggcgagag agggaagaaa agtcagactc ttagtcaaga attagacgag gctggatttg
    13801 ttagttattt aggggataag gagaattggt ggataggtct atccaaggaa aaacaaggtt
    13861 ccttcaccat tccctactat gtcttgggcc aagactggca gattttcatt tctggccaac
    13921 ctctagatgg tttagtcgtt acaccttttg aagctcctta tcaagaacac tttgaacgct
    13981 ggaagctgaa tgctgagaaa accctctttt acggttctgt aaatttgcag cagtctgaga
    14041 gtctctttgc ctattacgaa ccgatttata gggttatcat tcagggaaat ctcaatcaaa
    14101 tcgtagaaga gttaaatctc ttggagaagg tagttcttga aaatacgccg cgtgttccga
    14161 ttactaaaca gctttttatt cagtttgtca tggatgtttt ccatttattt gaacatctca
    14221 aagctgatga cctgacagac atcgtcaaaa ccattcatgc tattcaatcc ttcgatgaat
    14281 tggtttctta tatcaaggaa actctgatca gctttttcgg tcaataccgt atgaatgaaa
    14341 atgtggtcag tgtgctggaa gtcattggtc gtgattacca aaaagagctt tccctcaagg
    14401 atatcagtaa ggctctcttt atcaatcctg tttatctagg gcagttgatt aagcgtgaaa
    14461 ccgattcgac ttttgcagag ttactaaaca aacaacgtat taaggctgcc caacaacttt
    14521 tgctttcaac tagtgacagc atcgaagata tttgttatgc tgttggttac agtaaccttg
    14581 gatatttcta taaagttttc cgaaaattgt gcggaaaatc gccaaaagcc taccgaaaac
    14641 aggtagaaac tatactataa gatttgtatt cctttacaaa aggtgctata atattatcag
    14701 gaggttctat catgaaaaag aaaccaattt atctatgggt cttgctaatc ttgtctgccc
    14761 ttatttcagt tccgtctctg tttggaattg tgagtccctt gcctagtaaa gaagcccttc
    14821 gtgctgctca gaaacaagtt gcaggggtca atgctcagca attagaagac cagcttaatt
    14881 atacctatag agtagcagaa gcatctcatt ctatttttaa tgttgctttg attgtgctat
    14941 ctactatttt agtggtcgta gcgattgtct tccttgttcg taaaaatttg caatatgcaa
    15001 actatactta cgttggctat gttttgttag ctattattgg ttcgatttat ggctatgttg
    15061 gtttacaaga cgctgtgcag ttggttcaag atgagagcat gcgtttgaca gtgagtattg
    15121 gttcaaaagc tgttagcatt ttctatatcg tcatcaatgt tctcttccta gcccttgtct
    15181 tctataagat gtggcgacaa cagaaagcct tggcagaaga agaggaaaca gaagagctta
    15241 cctaagtatt gacaaaaaag aactatcaag atacaatctt ggtagttgtt ttttgattat
    15301 agataaaatc atggaggtac atatgaagac aatttcttta gtttatatta gtttgagtgg
    15361 caacactgaa agttttgtga cgcgcttgaa agactatctc ttgtcccagt acaaagggat
    15421 tgaggttcaa aagattcata tcaaggattt ggtcaaggaa ggcaaaaatt tctatgaaat
    15481 ggaccatccc tatgtcgctt ttttgccgac ctatctcgaa ggtgggaatg gcgtggataa
    15541 cggagatgtt gagattttga cgacaccggt gggagatttt attgcctatg gtaacaatgc
    15601 tagtaagtgt tttggtgtgg ttgggtcagg aaatcgtaac tttaataacc aatactgcct
    15661 aacagccaag caatacagtc aacgctttgg cttccctgta ttggctgact ttgaaatgcg
    15721 aggcatgctg gaagatatca aacatgtcgc agctattatc gcagatttgt atgagttgga
    15781 aaaggagaat taatactcaa tgaaaatcaa agagcaaact aggaagctag tcgcaggttg
    15841 ctcaaagcac agctttgagg ttgcagatag agctgacgtg gtttgaagag attctcgaat
    15901 agtataaagt tcttataaga tgtggttgaa gttgttcaac tgttttttga gtataaacag
    15961 tctttaagaa cgtaaaaaag cataagttca ggtcttcaaa accttgttct tatgcttttt
    16021 atcatagaaa tatttgctga attttctctt gaaatgaaac cttatcttca tctcgcgctt
    16081 gtcccttacc ctgcttttcc gattgcgagt gcgtagataa agaagatggc gaagccaaag
    16141 aggaaaatca atcccgcaat ggcaaggtgt ttgagccaag aaggaagatt tttgttttca
    16201 cgtgttacca aggcgtaatt caaaagagca aagaaaggtg ttgtcaggaa agagccaatc
    16261 atggcaaagc ggagcatggt tgaaacctga ccagcgaaga acttgataat gacgataccg
    16321 atgatagcag tgatggtcat ccagatgttc aaagatttac gattgtcctc tttttgactg
    16381 attagcagtc ggagagattc ctgattaacg cgagaatagc catcgataac agttataact
    16441 gttccaaaga tacagaggaa ggcaataaag gtaatcaagt aacgggacca ttcgccaaga
    16501 acagaggcat acatgcccac gaattgagag atgtatttgg ctgaagcagc ttcaaccgcc
    16561 tgccctgtag gatactgaat cagtgctccc agtgccacaa agaagacggc taggatagct
    16621 gttccaatat aaccagtgtt aaagtcaaac agagcgtctt ctgtgttaaa gttgacggtc
    16681 tttctctttt cagctgacca aagtgaattg atggctgaaa tttcaatagg agccggcatc
    16741 catcctagga gggagacgat gaagggcaga gctgccattt gccaaggtgt cttctcgaca
    16801 aaatcagaac tgtattctgg atgcttgacc gccgcaatga taactgcaag aacagtcgca
    16861 atggttaagg cagacataat ccatttgacc atgccgtcta aaagtttgta gcctccaaag
    16921 agtagcatag cccaaatgat tgcaacgaga atgagggacc actgagtaat gctaagtcca
    16981 atcattggga aggcactggc gatgatagct gagcacagaa tggcaacacc agccgtgttg
    17041 accatagccg aaaagacatt gagaataaag aaaatccaga gatagagttt tcctttttcg
    17101 gcataacctt caaccaaagt ctttccagta tcagctgtgt attcagcacc aaaacggaaa
    17161 aatggatatt taaagacatt ggctaagatg accaagagaa gtagagacca accgtaagaa
    17221 ccgccagctt gagttgagga tacaatgtgg gaacctccaa cagcggcagt tgccattagg
    17281 attccaggtc ccattgcttt tagcttgctt gcccaggttg attgatttaa ggaaatagct
    17341 tgcgacatga taaatactcc tttttgaatt ttcagaataa tctgtatatg caatctatat
    17401 tctacaaaaa attttggaaa aatgcaagaa tattttgaaa aaagatagaa aatttacaaa
    17461 gaaaatctga aataactgtt atgatatagc agattgaaac tagaatagta cacttttgct
    17521 tctaaaacat tgttagaaat cgatttgact gtcctgattg atttatcctg ttcttatttc
    17581 atttcactat agtaaggtgc agcaggataa agcaaaaccg agaagtttct ttctcggttt
    17641 tgcttattat gaggttccta ttttctatgc tccaagagtt gattgatgtg atctactttt
    17701 ttagcctctc ttttatagag aatagcccag atgatgagat agacaatcgc aaactcgata
    17761 atgagctgga ggtagaaaat ccagtggaag gggaaccaac cagcaagagt tgctagtggg
    17821 acaaagccag ccagcataag gaagaaatga gtcagagtgg cacgaagcat gctccagtca
    17881 cggctgaata agcggttgcc aaagttgaag agcataccga tggctgccca gataagtgtg
    17941 cagtagagca agaccagggc accgtgaacc tgatgctgat ccatcacttg gccgatgaga
    18001 gagtagggat ttagtggtgc gtaggtattt ggtgcataaa tgagtgaaaa gaggatggag
    18061 aggatgaggc cgataagaac accggcagct gcatcgtgaa atacttgttt tttcatagtt
    18121 ctaatttctc cttgatggtt tttagataac ggcgtgaaga gtaggtgaag ctttcgtttt
    18181 tcaagaaaat ttctaccaga ccgtttggcg tgagcttgag gtgagagatg gaatcgatat
    18241 tgatgatttc tgattgggaa atttggataa aattgcttgg caagagttta agaacctgat
    18301 agagtcgcaa atcaatgctg taggtctgac tcgcggtttc tgctagaacc ttccgattct
    18361 cgatatagaa gcgctgaatc ttgccaatct caactagata gacctgatca tcgatttttc
    18421 ctttgatttt ttctctttgg tccagatttt ctgcgaactc gatgactttc tggacttttt
    18481 cggtttcttg aggtgcttgg acaatcagct tttcctcctc gtaagtctca ctaatctgta
    18541 gttctacttt cataaatttc tctccttgtt tttcatacaa aattaatctc acttcttgta
    18601 cacctttatt aatactcttc aaaaatctct tcaaaccacg tcagcgtcgt cttgccgtag
    18661 gatagttgtt gactttgtca gttttatcta caacctcaaa acagtgtttt gagctgtctg
    18721 cgtctagctt tctagtttgc tctttgattt ttattgagta taccactatt ttactccctc
    18781 tggcaaggga ctttgtctat gtggagggat tgggctccta tgtggtggag tttttctgtt
    18841 ctttctgaaa tatggtataa tagcactaat taatttctag gaaaatagat acagaaaggg
    18901 gctgaaagat gtctcatatt attgaattgc cagagatgct ggcaaaccaa atcgcagctg
    18961 gggaggtcat tgaacgtcct gccagtgtgg ttaaagagtt ggtagaaaat gccattgacg
    19021 cgggctctag tcagattatc attgagattg aggaagctgg tctcaagaag gttcaaatca
    19081 cggataacgg tcatggaatt gcccacgatg aggtggagtt ggccctgcgt cgccatgcga
    19141 ccagtaagat aaaaaatcaa gcagatctct ttcggattcg gacgcttggt tttcgtggtg
    19201 aagccttgcc ttctattgcg tctgttagtg tcttgactct gttaacggcg gtggatggtg
    19261 ctagtcatgg aaccaagtta gtcgcgcgtg ggggtgaagt tgaggaagtc atcccagcga
    19321 ctagtcctgt gggaaccaag gtttgtgtgg aggatctctt tttcaacacg cctgcccgtc
    19381 tcaagtatat gaagagccag caagcggagt tgtctcatat cattgatatt gtcaaccgtc
    19441 tgggcttggc ccatcctgag atttctttta gcttgattag tgatggcaag gaaatgacgc
    19501 ggacagcagg gactggtcaa ttgcgccaag caatcgcagg gatttacggt ttggtcagtg
    19561 ccaagaagat gattgaaatt gagaactctg acctagattt cgaaatttca ggttttgtgt
    19621 ctttacctga gttgactcgg gctaaccgca attatatcag cctcttcatc aatggccgtt
    19681 atatcaagaa cttcctgctc aatcgtgcta ttttggatgg tttcggaagc aagcttatgg
    19741 ttggacgttt tccactggct gtcattcaca tccatatcga cccttatcta gcggatgtca
    19801 atgtgcatcc aactaagcaa gaggtgcgga tttccaagga aaaagaactg atgaccctgg
    19861 tttcagaagc tattgcaaat agtctcaagg aacaaacctt gattccagat gccttggaaa
    19921 atcttgccaa atcgaccgtg cgcaatcgtg agaaggtgga gcaaactatt ctcccactca
    19981 aagaaaatac gctctactat gagaaaactg agccgtcaag acctagtcaa actgaagtag
    20041 ctgattatca ggtagaattg actgatgaag ggcaggattt gaccctgttt gccaaggaaa
    20101 ccttggaccg attgaccaag ccagcaaaac tgcattttgc agagagaaag cctgctaact
    20161 acgaccagct agaccatcca gagttagatc ttgctagcat cgataaggct tatgacaaac
    20221 tggagcgaga agaagcatcc agcttcccag agttggagtt tttcggacaa atgcacggga
    20281 cttatctctt tgcccaaggg cgagatggac tttacatcat agatcagcac gctgctcagg
    20341 aacgggtcaa gtacgaggag taccgtgaaa gcattggcaa tgttgaccag agtcagcagc
    20401 aactcctagt gccctatatc tttgaatttc ctgcggatga tgccctgcgt ctcaaggaaa
    20461 gaatgcctct cttagaggaa gtgggcgtct ttctagcaga gtacggagaa aatcaattta
    20521 ttctacgtga acatcctatt tggatggcag aagaagagat tgaatcaggc atctatgaga
    20581 tgtgcgacat gctccttttg accaaggaag tttctatcaa gaaataccga gcagagctgg
    20641 ctatcatgat gtcttgcaag cgatctatca aggccaatca tcgtattgat gatcattcag
    20701 ctagacaact cctctatcag ctttctcaat gtgacaatcc ctataactgt cctcacggac
    20761 gtcctgtttt ggtgcatttt accaagtcgg atatggaaaa gatgttccga cgtattcagg
    20821 aaaatcacac cagtctccgt gagttgggga aatattaaaa gtataaaaaa gtctgggaaa
    20881 aattttcaaa atcagaaaaa cgcataaaat caggtgttca aaaaccttga ttttatgcgt
    20941 tttatcatgg aaatagttac ttcatgtttt cctaattctt ttcgaaactc tttttaaacc
    21001 acgtcagttt tatcagtaat ctcaaaacag tgttttgagc taattttgcc agttttgtct
    21061 gtaacatcga agttgtgttt taccactctg cgactggttt cctagtttgc tctatgattt
    21121 tcacagagta ttaaattgcg attttgccaa gtttctttat tcgtctaaaa gtagagtctg
    21181 ttctatgcgt ctaatgtacg aattaggttg accatttcaa tagctccttg tgcacactca
    21241 gaacccttat ttcctgcttt ggtaccagct cgttctatgg cttgttcaat tgtatctgtc
    21301 gttagcacac caaacataac aggaatttcg ctatttaaac tgatttgggc gattccctta
    21361 gatacctcgc tacatacata atcataatga cttgtattcc ctctaatgac agctcccaag
    21421 cagataattg catcatattt tttacttttt gccatttttg atgcaatcag tggtatttca
    21481 aaagctcctg gaacccaggc tacctctata tctttctcgt ttacattctc tcttttgaga
    21541 ttatctagtg ctccagataa taattttgaa gttataaatt cattaaatct cgctacaaca
    21601 atacctattt taatattgtt tgctactaaa ttaccttcat aagtgttcat ttatttttcc
    21661 tccatattta aaatgtgacc cattcgattt ttctttgttt ctaaataaaa actatcgtaa
    21721 ggattggctt ctatttcgat tgatattcta ctggaaatgg taattccata tttttctaac
    21781 tgttcaacct tgtcaggatt atttgtcagt aaatgaagtg actgaagtcc cagatcttta
    21841 agcatttgtg ctccaatatg atattctctt aaatcacctt caaagcctaa tgcaagattg
    21901 gcatcaagcg tatccatgcc ttgatcttgt aaatgatagg cttttaattt attgataagt
    21961 ccaattcctc gtccctcctg tcgcaagtaa agtaagacac ccgaaccatt ctcaacaatc
    22021 attttcatag ctttatcgaa ttgctgtcca caatcgcaac gtaaagagcc taaaacatct
    22081 cctgttaaac attcggagtg gacccgacat aatacattgg cttcatcctc tatgtttccc
    22141 ataataagag caagatgatg ttccccattt agtttatcta tatagctaat tgctttgaaa
    22201 ttaccgtatc tagtaggcat attgacagtt gaaactcgtt ctatcagctg atcatatact
    22261 tttctatatt cttgtaattc tttgatggta attagtggaa tgttgtgttt cttcgagaac
    22321 tgaattaaat catctgttct catcattttg ccatcatgat tcattatttc acaacatagg
    22381 ccacactctt ttagtccagc taattttaat aaatcaacag ttgcttctgt gtgtccattt
    22441 ctttctagaa caccaccttt ttttgcaatt aaaggaaaca tgtgtcctgg cctgcgaaaa
    22501 tcagagggtg ttatatcttc agctacacac atacgtgcgg tcagtcctct ttcctcggca
    22561 gaaatacctg tggtcgtttc tttataatca attgaaactg taaaagcagt cttatgatta
    22621 tctgtattgt tttcaaccat aggtgaaagc attaattgat tagctaaact ttcgctcata
    22681 ggcatacaaa ttaatccttt ggcataagta gccataaaat taacattttc tgttgtagct
    22741 gcttgtgcag aacaaattaa gtctccttca ttttctctat ccttgtcgtc tataacaaga
    22801 acaagtcgtc ccttctgcaa tgcttctaat gtttcttgta tttttcgata ttccattgac
    22861 tgattatcct ttctgctaaa atccattttg atataatagt tccttagata tttctgattt
    22921 tggagagtta tccatcagtt tttgcacata tttacctaag atatcatttt caagatttac
    22981 tgtactcccg acttgtttac ttttaagaat ggtttgtttc aaggtatgag ggataacaga
    23041 tactgaaaag tttactttgg agactttagc gacagtcaga ctaatgccgt caattgtaat
    23101 agatcctttt tcaactatta aatctaaaat ttctttttgt gtgttgattt gataccatac
    23161 agcattatca tcttttttta ttgacgagat ttttcctgta ccatcaatgt gtcctgtaac
    23221 gacgtgaccc ccaagtcgac cgttgataga taaggctctt tctagattca cctcacttcc
    23281 atgttttaat agagtaagag ctgttcgact ccatgtttca ttcattacat caactgtaaa
    23341 ggattgatga ttgaaatgag taactgtaag acagatacca tttactgcta tactatcgcc
    23401 taaatggata tccgttaata tttttgaggc tttaattgat agtttacaat tacgagagtc
    23461 tttctgtatt ctttcaactt ttccgatttc ttcaattatt cctgtgaaca tggataaatc
    23521 acttcacttt ctatgagata gtcatttcct atttgagaaa aagcataagg tttcaatcta
    23581 atagcgtcat ttggcaaaga aatgccttca cctccgacag gaaacttggc actgcctcca
    23641 aaaatttttg gtgcaatata tattttcagc tcatcaacaa tttgttgttc caaagcactc
    23701 caattcatta gactgccccc ttctagaact aggctatcaa tctgcatgtt tcctagatgt
    23761 tgcattaaac tcgataagtc tatatgattg ccttttttct ttatggaaag tatttcacag
    23821 ccatgatttt gatatagctt cattttattt ttgtcttcag aggaagtggc aatgtaagtt
    23881 ttaatatcat ttgctgtttt tacgatttta gaggtaagag gagttcgtaa atgtgtatcg
    23941 catatgatac ggataggatt tttcccttcc tccaatctac atgtcagcaa aggatcgtct
    24001 tgaataacag tattgactcc caccataatt gcactaacat ggtgtcgtaa ctgatgcaca
    24061 tgctttcttg cttcttcttc agtaatccat ttggattgat ttgttttagt ggctattttt
    24121 ccatccattg acattgcata tttcataaaa acatagggta catgctgggt aatatacttt
    24181 ctaaaacttt ttattaagtt aagacactca ttttctaaaa ttccaacagt aacttgaaga
    24241 ttattttcct caagtatctt tactcctttt ccagatacaa taggattaca gtctaggctt
    24301 ccaatgacta ctcttgtaat accactatcg attatagcat ctatacaggg aggtgttttc
    24361 ccgaagtgac aacagggttc aagtgttaca taaagcgtcg ctccgacagg ggattctcta
    24421 cagtttttaa gagcatttct ctcagcatgt gggccaccaa aaaactcatg ataaccttgt
    24481 ccgatgatgt gattatcttt tacaataact gcgccgacca taggattggg attgacgtaa
    24541 ccagcccctt tttgtgccag ttttattgct aatttcatat attttgaatc gctcatctca
    24601 ctacctccaa aaaaaatata ccttgaatag gggactactc aaggcataca aaagaaaact
    24661 tatgcgatta acaaaaatac tctgaaatga caagtaatca tttcagagca cgcaaaaagc
    24721 acaaatatac ttttatcttc tttcatccag actatactgt cggctttgga atttcaccaa
    24781 atcatgcctt tcggctcgtg ggctatacca ccggtaggga attacaccct gccctgaaga
    24841 tagttattca attacagatg attatagtac ttaattttga atatgtcaac agataaatac
    24901 cgattgtttt tgatatactg tatttgtgat aatcgattct cgctcctcgg ataaagaaaa
    24961 tatgatatac tagataaacg aaataagaga gaaggaatac tatgtacgca tatttaaaag
    25021 gaatcattac caaaattact gccaaataca ttgttcttga aaccaatggt attggttata
    25081 tcctgcatgt ggccaatcct tatgcctatt caggtcaggt taatcaggag gatcagattt
    25141 atgtgcatca ggttgtgcgt gaggacgccc atttgcttta tggatttcgc tcagaggatg
    25201 agaaaaagct ctttcttagt ctgatttcgg tctctgggat tggtcctgta tcagctcttg
    25261 ctattatcgc tgctgatgac aatgctggct tggttcaagc cattgaaacc aagaacatca
    25321 cctacttgac caagttccct aaaattggca agaaaacagc ccagcagatg gtgctggact
    25381 tggaaggcaa ggtagtagtt gcaggagatg accttcctgc caaggtcgca gtgcaagcaa
    25441 gtgctgaaaa ccaagaattg gaagaagcta tggaagccat gttggctctg ggctacaagg
    25501 caacagagct caagaaaatc aagaaattct ttgaaggaac gacagataca gctgagaact
    25561 atatcaagtc ggcccttaaa atgttggtca aataggagca gagaatgaca aaacgttgtt
    25621 cgtgggtcaa gatgacaaac ccgctctaca tcgcctatca tgatgaggag tggggtcagc
    25681 ccctccatga tgaccaagca ttgtttgagt tgttgtgtat ggaaacctat caggcaggcc
    25741 tgtcttggga aacggtactc aacaaacgcc aagctttccg agaagccttt catagctatc
    25801 aaattcactc agtcgcagag atgactgaga ctgaattgga agccatgctg gagaatccag
    25861 ctatcattcg aaatagagcc aagctttttg ctacacgcgc taacgcccaa gtccttctac
    25921 agttacaggc agagtacggc tcttttgatg cctatctttg gtcttttgtt gaggggaaaa
    25981 ttgtcgttaa cgatgttcct gattatcgcc aagcgccagc taaaacaccc ttatctgaga
    26041 aattagccaa agatctcaaa aaacgaggct tcaagttcac aggcccagtc gccgtattgt
    26101 cttttctaca ggctgcaggg ctagttgatg accacgagaa tgattgtgag tggaaaggtc
    26161 ttaaatgatg tctaacaaaa ataagggaat tctgattttt gcgattctct atacagtcct
    26221 ctttgtgttt gatggcgtta aattgctggc ttctttaatg ccatctgtca ttgcaaatta
    26281 tcttgtttat gtagttttag ctttatatgg ctccttcttg ttcaaggata gattgatcca
    26341 acaatggaag gagattagaa agactaaaag aaaattcttc tttggcgtct taacaggatg
    26401 gctctttctc attctgatga ctgttgtctt tgaatttgta tcagagatgt tgaagcagtt
    26461 tgtgagacta gatggacaag gtctaaatca gtctaatatt caaagtacct ttcaagaaca
    26521 accactactg atagctgttt ttgcttgtgt cattggacct ctggtagaag aattattttt
    26581 ccgtcaggtc ttattgcatt acttgcagga acggttgcca ggtttactaa gcattattct
    26641 ggtaggactt gtttttgctc tgactcatat gcacagtttg gccctatcag agtggattgg
    26701 tgcagttggt tacttaggtg gaggccttgc cttttctatt atttatgtga aagaaaaaga
    26761 gaatatctac tatcccctac ttgttcacat gttaagcaac agcctctcct taatcatttt
    26821 agctatcagt atagtaaaat gaaatgagaa caggacaaat cgatttctaa caatgtttta
    26881 gaagtagagg tgtactattc tagtttcaat atactgtaat atgtgatgaa aatgccagta
    26941 atgataccga gaaaaaagct gagaaacttt tcccagcttt atttgttata gtcaaagaga
    27001 atgacttgtt cctgtgcatc tacatgagca tggaccccaa agggtacaat tgctcttgga
    27061 gttgcgtggc cgacattcag attatagaca atcgggatat tgctgtcaat gatatccaat
    27121 agtgcctctt tatagtcgtc atggaaagtt tcatccatag gttttccgac caagagtcca
    27181 ttgatgaccg cgaatatgcc agtgtccttt aaagttagca acatcttttt gaagtcttct
    27241 ggcttaggct tttcttcgct tgtttcgagc aagaggattt tcccttccca gtctgacaag
    27301 tcagggaaaa gtttgtattt ttggcagagt tccgtgctat ctgcgtatcg agagttgtca
    27361 aagatatcgt agagggattc gaggcaacca ccgaggattt tcccctcgaa ctgggcactt
    27421 ccttgcaaca agtcaaaacc tgtatttgta tgactgacac gaggtgttcc cagggccgtg
    27481 ggactaaaat cagttcgttc ctcataccaa acgtcactag ggcggatttc tgaaattctt
    27541 cccgtctcaa tcaattcttt aaagtagtga aggctatagg ctagcatttc tttgtctaat
    27601 tcacaaatgt ctgctaaaaa ggattgacca taaaaagtct tgattcctaa tttatgcaac
    27661 atgaggtggt tcatggttgt atccgagaag ccaagaaaaa ttttttgttt gataaccttt
    27721 tggagttggt cattttcaaa aagataaggt agcaagcgat aggtatcgtc tccaccgatg
    27781 gcacatagga tcatgtcgat gctatcatca gaaaaggcat gaatcaaatc ctctgcacga
    27841 gcttcaggat ggtccttgat aaagtctaat ccttttaacg aatggggcaa aaagatggga
    27901 ttgagtccca gatccttgag acgttggata cccaagtcca cttcgtgttt gacaaaatcc
    27961 tctccgataa tgccactaga taaactaaca ataccaatag tagaaaccat atctcatcct
    28021 cctagaaata gattgagcct attttatcac aaaatataag agaaagctat gtgggatttc
    28081 agaagaatac ttttaatact cttcgaaaat ctcttcaaac cacgtcagtt ttatttgcaa
    28141 cctcaaagct gtgctttgag caacctgcag ctagcttcct agtttgctct ttgattttca
    28201 ttgagtataa ctcaaaaaag taagtgaaaa agcaaccgca cctgcagttg cttttatcgt
    28261 tttcttattc ttgatagcgt gttggtcctg cacttgcact acggatattc aagcgtttct
    28321 tgagatagaa gcgaagggct aggagggcta ctccaataat agctagtggc aatggatcca
    28381 gtactgggtt aaggctagct ggtaggaagc ttgttgcaaa gaagacaagc aaccaaagga
    28441 acatagaagt taggataact agtacagatt tccagaaagg tggacgttga ctgcgatcca
    28501 tatctggtcc atagtattgg taaacaaagt agtacatcaa gtagaaggca aatccaccaa
    28561 ccagtccaac taatagaaga gtaatcaatc catagccgaa agcttgatct gccgcaaaga
    28621 aggttgtgag ggcgctgaca agggcaaaga ggctagtgat gaaaagagct gagtccataa
    28681 tcatcagttt tggatcatca ttttcttttg gatgctcttt ttcgtactgc tctttgacag
    28741 tgaagctatg agcccaatga gttggtgcgc cgtataggga acgggcagtt gtacctttag
    28801 attgctcctc aaggatttgg ggaatgactt cctcaaaaat agtctggatt tcagcgtctg
    28861 ttttcccatc tttgatgaat tgttgggtag caatgtggac aaactcttgg tttttcttag
    28921 ttaatttttg tagatcaatt tgagacatag gaactcctct tagaaccatt ttttatggat
    28981 gagatagaga gtgagcgaga cactcatagc aaaggcgata aagacgatta accagaaggc
    29041 atttggctct ccgtttaggg gaatttcatt atccttaaag ttcatcccgt aggcagaaaa
    29101 gaccatggtt gggatggaca tgacgatggt cacaagggcc aaggttttca tgatgttgtt
    29161 ctggttgtta gaaatgatag aggcaaaggt ctctgtcata gaatgcaaga cgtttccata
    29221 aatatctgcc atctcgatgg cctgttgggt ttcaatcagg gtgtcttcaa gcaggtcttc
    29281 gtcctcaagg tatttcttga tattgctggt tgaactggtc aatttcttaa tcacgcgctc
    29341 atttgttttg agggaggcct tgaaatagac gatagttttt tccaattcca tgagctcaat
    29401 caattcttca ttacgagttg attgatgcag ttgactttcg atttgttcac tcttgcggtc
    29461 gattgaacga agggctgtta ggtaaagctc tgcattgcga taaagaattt gaaagataaa
    29521 acgtgaacgc atgaaggtat agaaattacg caatcgacgg ttgataaaga catcaaggac
    29581 aggtagtggt tccaaacacg tagtgataat ggtttcctca gtgatgataa taccaagcgg
    29641 gatggttacg tagtaggtgc ggttatttct ttcctccgtg accggcacgt ctacgataat
    29701 cagggtatac tcgtcttcaa tggtaatacg agacatttct tccgcatcga gcggtgctcg
    29761 aaggtcggca atatcaatat cgaaggtgtt ggcgatttcg agtgattcat tttgagtcgg
    29821 attgacgaga ttgatccaag tacccggttc aagcgtatcg atctctttaa attcagttgt
    29881 tgtagagaga aaaacttgtt tcatatccct tatcctttct catttttcag attttttcac
    29941 actgtactat tatactacaa aatcggcctt ttgggtaata gaatctcact ttttttggta
    30001 taatggtaag caataatgga ctagaaagaa caaagatgca agataaaatt gtcattcatg
    30061 gggcgcgtgc ccataattta aaaaatattg atgtggagat tccgcgagac aagttggttg
    30121 tcgtgactgg cttgtcaggt tcagggaagt ccagtctggc ttttgatact ctctatgcgg
    30181 agggacaacg tcgctatgta gagagtttgt ctgcctacgc tcgtcagttc ttgggaaata
    30241 tggaaaaacc agatgtagat gccattgatg gtctcagccc agctatttcc atcgaccaga
    30301 aaacgactag taaaaatcct cgctcgacgg tgggaacgac gactgaaatc aatgactatc
    30361 tgcgtctcct ctacgcacgt gtggggacgc cttactgtat caacggacat ggagctatca
    30421 atgcttcttc tgtggagcaa atcgttgata aggttttgga gttacctgaa cgccagcgct
    30481 tgcagatctt ggctcctgtc atccgcaaga aaaaaggcca acataagagt gttatcgaga
    30541 aggttcagaa agacgggtat gttcgtgttc gtgtggatgg ggaagtctat gatgtgaccg
    30601 aagtgccaga gttgtctaag agcaagcaac acaatatcga tgtcgtggtt gaccgtattg
    30661 ttatcaagga gggcattcgt agccgtctct ttgattccat tgaagctgcc cttcgtatcg
    30721 cagaaggtta tgtgattatc gacaccatgg acgactctga gttgttgttc tctgagcatt
    30781 atgcctgtcc agtttgtgga tttactgtcc cagagttaga acctcgtctc ttctctttca
    30841 atgctccctt tggctcttgt agtgagtgtg acggcttggg gattaagctg gaggtggata
    30901 ctgatttggt agtgccagat gccagcaaaa ccttacatga gggagcgctg gcaccttgga
    30961 atcctatctc atccaactac tatccaaaca tgttagagca ggccatgaaa gtctttggag
    31021 tggctatgga taagcctttt gaggacctgt cagaagaaga taagaacttg attctctacg
    31081 gctcagatgg taaggaattc catttccatt atgaaaatga atttggtggt gtgcgcgata
    31141 tcgacattcc gtttgaggga gttatcaata atatcaaacg tcgttaccat gaaaccaata
    31201 gcgattacac tcgcactcag atgcgtctct acatgaatga gctgacctgc ggaacctgtc
    31261 aaggctatcg tctcaatgac caggccttgt ctgtccgtgt gggcggccag caagggccac
    31321 atattggaga aatctcagac ctgtctatcg ctgaccactt ggacttggtg agccagttaa
    31381 ctttgtctga aaatgaagcc atcattgctc gtcccattct caaggaaatc aaggatcgtt
    31441 tgaccttcct taataatgtg ggtcttaact atctaaccct gtcacgttca gcaggaaccc
    31501 tttcaggtgg ggaaagtcag cgcattcgtt tggcaaccca gattggttcc aacctatcag
    31561 gtgtcctcta tatcctagac gagccgtcaa tcggtcttca ccagagggac aatgaccgcc
    31621 tgattgccag tctgaaaaag atgcgtgact tgggcaatac tcttatcgtg gtggaacacg
    31681 acgaagatac catgcgtgaa gctgattatc tgattgacgt tggtcctggt gccggtgttt
    31741 ttggtggtga gattgttgca gcaggtacac ctaagcaagt ggctcgcaac agcaagtcta
    31801 tcacaggtca gtacttgtca ggcaaacgtg tcatcccagt accagaagag cgccgtgtcg
    31861 gaaatggtcg ttttattgaa gtgacaggag cgcgtgagaa caacttgcaa aatgtcacgg
    31921 ctcgctttcc actaggaaaa tttatcgcag tgacaggtgt gtcgggttca gggaaatcga
    31981 ctctaatcaa cagcattctc aaaaaagcca ttgcccagaa gctcaaccgt aattcagaca
    32041 aacctggtaa gtttaagact attacaggga ttgagcatgt cgaccgtttg attgatattg
    32101 accagagccc tatcggacgg acgccgaggt ctaacccagc tacctataca ggagtttttg
    32161 acgatatacg tgaccttttt gctcagacaa atgaagccaa gattcgaggc tacaagaagg
    32221 ggcgcttcag tttcaacgtc aagggaggtc gctgtgaagc ttgctcaggt gacgggatta
    32281 tcaagattga gatgcacttc ttgccagatg tttatgtggc ttgtgaagtt tgccacggaa
    32341 cccgctataa cagtgaaacc ctagaagttc actacaagga aaagaatatt tcgcaggtct
    32401 tggatatgac ggtcaacgat gcggtagaat ttttccaaca cattccgaaa attcaacgca
    32461 aactccagac catcaaggat gtaggtctag gctatgtgac cttgggacag ccagctacca
    32521 ccctttctgg gggagaagcc caacgtatga agttagctag cgaactccac aaacgctcga
    32581 caggaaaatc tttctacatt ctggatgagc cgacgacagg gcttcataca gaggacattg
    32641 ctcgcctgct caaggtttta gctcgctttg tagacgccgg caatacagtc ctcgtcatcg
    32701 agcacaatct ggatgttatc aagacggcag accatatcat tgacttggga cctgagggcg
    32761 gtgtcggtgg tggaaccatc atcgtaacag gaactccaga agaagtagct gccaacgaag
    32821 ccagctatac aggacactat ttgaaaggaa agttacatca tgaataaacg cgtacaagca
    32881 tttctagcta aaatgcaaga aaaagaacta gatggtatca tcatcaacaa tcttaaaaac
    32941 gtctattatt tgactggttt ttggggctca aacggaacag tctttatcag ccgtgaccgt
    33001 caggtcttag tgacagactc tcgctatatc atcgcagcta agcaagaaac cagtggtttt
    33061 gagattgtgg ctgatcgtga tgaattggct gtcattgcag gaattgttaa ggacatgaac
    33121 ttgactcgta tcggttttga agatgagatt tcagtgtctt attaccaccg tatgcaggca
    33181 gcttttgcag gtttgaactt gcttccacaa actcagtttg tggaaggtct tcgtatgatt
    33241 aaggatgagg cagagattgc agcgattcgc aaggcttgtt ctatctcaga ccaagctttc
    33301 cgcgatgcgc ttgactttat caaaccagga aaaactgaaa ttgagattgc caacttcctt
    33361 gatttccgca tgcgtgagtt gggagcatct ggcttatctt ttgatacgat cctagctagc
    33421 ggtatcaatt cttctaaacc ccatgcccat ccaatgcaca aaccagtgga gttgggagaa
    33481 gccattacca tggacttcgg ctgtctctat gaccactatg tcagtgatat gacccggact
    33541 atctatctag ggcatgttag cgatgagcag gcagagattt acaatacggt tctaaaagct
    33601 aaccaagcct tgattgacca agctaaggca ggcttaggtt tccgtgactt tgacaaaatc
    33661 cctcgtgata ttatcattga ggcaggttat ggtgactact ttactcacgg cattggccac
    33721 ggtattggtc tggatatcca tgaggaaccc tactttagtc agacttctac agaaactatt
    33781 aagacaggta tggccttgac cgatgaacca ggtatctata tcgaaggcaa atatggcgtt
    33841 cgtatcgagg atgatatcct gattacagag acaggttgtg aattattgac cctagctcca
    33901 aaagagttga tagtcattta gttgtttgtc aagaaaaaag tacgaaaatg acgaaaaaag
    33961 tcaaaaaaaa ttaaaaatag gtcgcaagtc ggatgttttt tatggtataa tagactaaac
    34021 tgatagtaac atgtagcgaa aggggtaggt acatgattaa aatttataca gtctcaagtt
    34081 gtactagttg taaaaaagca aaaacctggc tcaatgccca ccagttaagt tataaagaac
    34141 aaaaccttgg taaagaagga attacgagag aagaattact ggatattcta accaaaacag
    34201 ataacggaat agccagcatc gtttcgtcta aaaatcgcta tgccaaagcc cttggagtgg
    34261 atattgaaga tttgagtgtc aatgaagttc tcaatctgat tatggaaaca ccgagaattt
    34321 taaagagccc aatccttgta gatgaaaaac gcctgcaagt tggctacaag gaagacgata
    34381 ttcgtgcctt cctaccacgc tctgtccgta atgtagaaaa tgcagaagca cgtttgcgtg
    34441 cagctctata aacatcaagg ctgggagcac ttcccagtct tattctattt taatttcaaa
    34501 aagaaagaag aaagaaatga aaaaaatagt tcttgttagt ctagctttcc tttttgtcct
    34561 ggttggttgc ggacagaaaa aagaaactgg accagctaca aaaacagaaa aagatacgct
    34621 tcagtcggca ttgccagtta ttgaaaatgc tgagaagaat acagttgtaa ctaagacttt
    34681 ggtcttgccc aagtcagatg atggtagcca gcagacacaa acaattactt acaaagacaa
    34741 gacttttttg agtctagcta tccaacaaaa acgtccagtc tctgatgagt tgaagactta
    34801 tattgaccaa catggagtgg aggaaactca aaaagctctt cttgaagcgg aggagaagga
    34861 taagtctatc attgaagctc gtaaattggc aggtttcaaa cttgaaacaa aactattgag
    34921 cgcaacggaa cttcaaacaa cgactagttt tgattttcaa gttctggatg tcaagaaggc
    34981 ttcccagttg gaacatctga agaatattgg tttggaaaat cttttgaaaa atgaaccaag
    35041 caaatatatt tcagatagat tggcaaatgg cgcgacagaa caatagaaaa tccaaataaa
    35101 tagactgcct gaattgtaga aggtaaggaa ttatgctata atggtactat tctaaggaaa
    35161 gagggtgtta gaatgggatt tactgaagaa acagtacgtt ttaaattgga cgattccaat
    35221 aaaaaagaaa ttagcgaaac tttgacagat gtttatgctt cgttgaacga taagggttac
    35281 aacccaatta accaaatcgt aggttacgta ttgagtggag accctgccta cgttcctcgt
    35341 tataataatg cacgaaatca aatccgtaag tatgagcgtg atgaaatcgt tgaggaattg
    35401 gttcgctact acctcaaagg acaaggagtc gatctataac ctatgagaat tatgggattg
    35461 gacgtcggtt caaaaacggt aggggtggcg attagcgatc cgcttggttt tacagctcaa
    35521 gggcttgaaa tcatccagat aaatgaagaa caaggccaat ttggttttga ccgcgttaag
    35581 gaattggttg atacttacaa ggtggaacga tttgtagtgg gcttgcctaa aaacatgaac
    35641 aatacaagtg gaccgcgcgt agaagctagt caagcctacg gagcaaagct agaagagttt
    35701 tttggtttac cagtagacta tcaggatgaa cgcttgacaa cagtggctgc tgagcgcatg
    35761 ttgattgaac aagcagatat cagtcgcaat aagcgcaaga aagtcattga taagttagca
    35821 gctcagctga ttttacaaaa ttatttagat agaaaatttt aatataaagg agaggctatg
    35881 tcacacgatc ataaccacga ccacgaagaa cgtgaactaa tcacactagt agatgagcaa
    35941 ggaaatgaaa ccttgtttga aatccttttg acaattgatg gaaaagaaga atttggtaaa
    36001 aactatgttc ttctagtacc agttaacgca gaagaagacg aagacggaca agttgaaatc
    36061 caagcttact cattcattga aaatgaagat ggaacagaag gcgaattgca accaatccca
    36121 gaagactcag aagacgaatg gaacatgatt gaagaagtct tcaacagctt tatggaggag
    36181 tgatacagtc tgggagactg tatcagccca actccagaaa tggggaagag ttggaacgtc
    36241 cagtgaacat ttttacccca actcttagaa attgagaaga gttggaacat ctagtggatg
    36301 tttttagccc atattcacat tcatagtagc tagttattag ctaaccaggt aagaggtcgg
    36361 gacgaaaatc ctggccttgt ttttattagt aaccatactt taatgcgata attgattgga
    36421 cttttgtcaa ggagatgtgt atgtttgaag tagaagaatg gctccatagt cggattggtt
    36481 tgaattttcg atcaggtttg ggccgaatgc agcaagcggt ggatttgtta ggaaatcctg
    36541 agcagtctta ccctattatc cacgtaacag ggactaatgg gaaaggatct accattgctt
    36601 ttatgaggga attatttatg gggcatggca aaaaagttgc gacctttacc tcccctcata
    36661 tcgtctctat caatgaccga atctgcatta atgggcaacc tatagcagac gcagacttta
    36721 tccgtttgac tgatcaggtc aaggagatgg agaaaacgct tctgcaaact cctgcccagt
    36781 tgtccttttt tgaattgctg accttagttg cttttcttta ttttagggag caagaggtgg
    36841 atttggtttt attagaagtg ggaattggtg gcttacttga cacgaccaat gtggtaactg
    36901 gagagcttgc tgtcatcacc tccattgggc ttgaccatca agaaaccttg ggtgatagtc
    36961 tagaagcaat tgcagagcag aaagctggta ttttcaaggc tggtaaaaag gcagtgattg
    37021 cgaaattgcc tccagaagct agacttgtct gtcagaaaaa agccgaatct ttagctgttg
    37081 acctttatca ggcaggtcaa gatttttcag tgctgaatgg tgatttttca agctctttac
    37141 taaatctttc acagctgaac ataggcttag aaggagccta tcagcaggag aatgcggcct
    37201 tggcgttgca aacttttctt ctttttatgg gagaaagaaa ggaagctatt gatgaacagg
    37261 ctgtaagaaa ggccttggaa cagacccatt gggctggtcg cttggagcgt attcgcccac
    37321 agatttactt ggatggtgct cataacctcc ctgccttgac tcgcttggtt gagtttatca
    37381 aagaaaaaga gcaggaaggc tatcgacctc aaatcctctt tggatccttg aaacgtaagg
    37441 attatcaagg gatgttgggt tatctgactg aaaatttacc tcaagtggaa ctcaaaatga
    37501 ccggctttga ctatcaaggg tctttggacg agacagatgt aacaggttac catgtaattc
    37561 cctcttaccg agaatttatc agcagtttcg aagaaagggc agacgctcaa gacttgctgt
    37621 tcgttacagg gtctctctat tttatctcag aagtacgggg ctacctgctg gaccgtgagc
    37681 agataaattg accccctttt ttgaacttgt tatactaggg gaattgctgg ttagagaaaa
    37741 tttctctaaa ttggtagcag aaaggaaatt catcatgaaa ttaaaaagat tcacactttc
    37801 tcttgcttct ctagcaagtt ttagtctctt agtagcttgt tcacaaagag ctcaacaggt
    37861 tcaacagcct gttgctcagc aggtccaaca gcctgctcaa cagaatacca atactgcaaa
    37921 tgcaggaggt aaccaaaatc aagcggctcc agtacaaaac caacctgttg ctcaaccgac
    37981 cgatattgat gggacttata ctggtcagga tgacggagac cgtatcactt tagtggtaac
    38041 tggaacgact ggtacatgga ctgagctcga atctgacggg gatcagaaag tcaaacaggt
    38101 tacatttgat tcagcaaatc aacgcatgat tattggcgat gatgtcaaaa tttacactgt
    38161 aaacggtaat caaatcgtcg tagatgatat ggatagagac ccatcggacc aaatcgtttt
    38221 aactaaataa gactatgcaa gtagaaaggg ctggattttt cagccttttt acttttacct
    38281 agaaaataat cataaatact tgccttctac cgaatacctg cgttatacta gtatcaatta
    38341 cttgttttta gcattcaaac tatcaaggag gggatatgaa atataggaaa tttcaattat
    38401 tgatgtccaa gtatggcttt agtctttcga ttatgctact tgaactttgt cttgtttttg
    38461 gtctctttct ttatttagga cgcatggctc ccattttatg gattactgtc ctcattctac
    38521 tgagtatcat cacaatcatt tcgatagtca accgtaatac gactcctgag aataaggtaa
    38581 cctggttgtt agtagccttt gtgccagtat ttggtccctt gctctatctg atgtttggtg
    38641 aaaggcgatt gtccaaaaaa gaaatcaaac aactgaagaa gctaggctct atgcatttcc
    38701 aagaagcaaa tagccagcta ctaaaagaga aattaaaaga aagtgacaag gcagcttatg
    38761 gagtcatcaa gtccttattg agtatggata ccaatgctga catctatgat caaactgcct
    38821 ctacattttt tcctaacgga gaagctatgt ggaaaaagat ggtagaagat cttaaaaagg
    38881 ctgagaaatt tattttcttg gaatattaca ttatagaaga aggtttgatg tggaatcgca
    38941 tactagatat actagagcaa aaggtagctc agggtgtaga ggttaagatg ctctatgatg
    39001 atatcggctg tatggctact ttaacaggag attatgcaca tcgacttcgt cagctgggca
    39061 tcgaggccca taaattcaat aaagttattc ctcgtttgac agtggcttat aataacagag
    39121 atcatagaaa aatattgatt gttgatggtc agatagccta tactggtggg gtcaatctgg
    39181 cagatgagta cattaaccac gtcgagagat ttggttattg gaaggatagt ggaattcgct
    39241 tagacggact agcagtaaaa gccctgacac gcttattttt gaccacttgg tacattaatc
    39301 gaggagaaat tagtgatttt gatcaatatc atttagaaaa tcattctatc ccgagtgacg
    39361 gtttaaccat tccatacgga agtggaccca agccaatttt tcgagcgcag gtagggaaaa
    39421 aagtttatca gagtttaatc aatcaagcaa cagaatcggt ctatattacg acaccttatt
    39481 tgattataga ttatgattta acagagacaa tcaaaaatgc agctatgaga ggggtcgatg
    39541 ttcgaattat caccccttac ataccagata agaagttcat tcagttagtc acgagaggag
    39601 cttatcccga ccttctttct gctggtgttc ggatttatga gtatagtcca ggttttattc
    39661 atagtaagca gatgttggta gacgaagatt ttgcggtggt ggggacaatc aatctcgact
    39721 accggagctt ggtacaccat tatgaaaatg cagtcttact ctataaaact ccttctataa
    39781 gggaaatcgc ccgagatttt cgaaatatat ttgcagattc tcaggaagtc tatcctcatt
    39841 ctatcaaaac gagctggtat caaaagcttg taaaagaaat cgcccagcta ttcgccccta
    39901 tcttataaga aatctagaac ttaggataca aaccagacct atttttcttg tcttttacta
    39961 atagaaagaa agaggagggg aattcatgct aactaaggaa gaagtgaatg atatgattga
    40021 gttcaaacag acacatttat accgctttcg ggaaattgaa acctttgtga aactatgcaa
    40081 aaaatcactc aaacagccat cgcaagctga caatcctagg actttttgat atactaagac
    40141 agataaattg aacaggagaa acgatatgag tgtgtatggt agagtagaag aagttcataa
    40201 ggagaatcgt gaacctctag aataccaaat cgaacaagaa tcgcatcatc gtgaatcaag
    40261 tcgtcttcct ttggtgaaaa ttttactatg gagtacgctt gtaacgggga taactctagg
    40321 agtaccgcta ttactcgact taatgagtgc acaagaagtg caggattttt atgcaggttg
    40381 ggggcttcat cagacaggga agatttacag cgactattat ggaagtcaag gtttgcttta
    40441 ttatttgctg acttacgtga gtcagggcgg atttttcttt gccatctttg agtggttagc
    40501 cttggtagca ggaggatttt tcctttttag atcagcggac accttgacag agcaaggaga
    40561 ccaagctgga catctggtga ctatttttta catgctagtt acaggtcttg cttttggtgg
    40621 aggctatgcg actcttttag cgcttccttt cttattcgca gcctttagtt tagttgcggc
    40681 ttacctaagc aatccaagcc atgataaggg atttgtacgg attgggctag ctttggcagg
    40741 cggatttttc tttgctccct tatcatcgct cctgtttatt gctgtagtga gtttaggctt
    40801 gttggtcttt aaccttgggc atagacgctt tgcgcatggg ttttatcagt ttcttgcagt
    40861 ggctttaggt ttttcacttg tcttttatcc aactgcctac tatagtgctg caacaggaag
    40921 ttttggggat gcgattagtg gtattcgtta tcctattgac agtattcgct ttgattttac
    40981 ttctaaaatt ttagagaata tgttttttta tggcttgttg tcccttggtt tgggatttgt
    41041 ggtttgtatc tttttaggtc tctttcaatc caaacccttt aaactatacg tcatttcggt
    41101 tcctgcaagt cttgtggtaa ttttaggttt gattttactt ttcttttcac aagagcctct
    41161 gcacgcttct tatttgatgg tcgtcttccc tgttttccta cttttattgg taaccaatat
    41221 taagagtcaa cagagggggc gtagtgctag aagaagccga agagaaacgc cagttagcct
    41281 atggagtcgt ttcttcaaag gaaatctata tctgctagtt tttgggtttg tctatctttt
    41341 gtctgttcct tttttgatga agtttgtcct ttatccagta ccttatcaag aacgtaatcg
    41401 tcttgctgat ttggtaaaag aggagacaaa tacggaagat gctatctatg catgggatga
    41461 tactgcgact ctttatcgta agagtgagcg cttgtcgcca tcggcgattt tgtccccgtt
    41521 gcactataca gcaactgagg aaaatcgtaa taagttactt aatgacttga aagaaaaaca
    41581 acctaaggtg attgtggtaa atgacaaggt ggtagtctgg tctgaagtgg aaacactttt
    41641 aaaagaaaat taccaacaag taaagactga ttactcagag tttaaagtct ataaaattaa
    41701 ataaccaaat caatatcttg tgtattttta aaaattttag gatttttaac acaagatatt
    41761 gatttttctt tttagagtgg tataatactt tttagaaaga acattttaga aaagagcatg
    41821 cgtatgattg cactagaaga aaaaattaca attttgccaa ctctcttcgt cgagaaacga
    41881 gatgggagac gtgttgtatt tgatgtggac aagattgaca aggctctcca caaggcggct
    41941 gacaaggtta tggatgtgac acccctggtt gaaaaacgcc tcaatgatct gactgagcga
    42001 attattacag aaattcatag tcgctttcca cagggaatta agatttacga aattcaaaat
    42061 atcgtagaac atgaactcct tgaagccaaa gaatatgcgc tggctgagga gtatattact
    42121 tatcggacac agagggattt tgagcgctca aaagcgacgg atatcaactt tagtattcat
    42181 aaacttctca acaaagacca gacagttgtc aatgaaaatg ctaataaaga cagtgatgtc
    42241 tttaacactc agcgtgattt gacagcaggg attgttggga aatcaatcgg actgcaaatg
    42301 cttcctaagc acgtagccaa tgcccaccaa aagggggata tccactatca cgatttggac
    42361 tacagtccct atacccctat gaccaactgc tgtttgattg attttaaggg tatgttggaa
    42421 aatggtttta agattggaaa tgcagaggta gagagtccca agtctatcca gactgcgaca
    42481 gcacagattt ctcaaatcat tgccaacgtt gcttctagcc agtacggtgg ctgttcagct
    42541 gaccgtatcg atgaaatttt ggcgccttat gcagagaaga attatcaaaa acatctcaaa
    42601 gatgcagaag agtgggtatt gcctgaaaaa cgggaagatt acgcttggaa gaaaacgcaa
    42661 aaggacatct acgatgccat gcaatctctt gagtatgaaa tcaatactct cttcacttca
    42721 aatggacaaa caccttttac ttcgttaggt tttggtctgg gaaccagtcg ttttgaacga
    42781 gaaattcaaa aagctatttt aaacattcgc atcaagggtc ttggttcaga acaccgtacg
    42841 gctatctttc ctaaacttat tttcactctg aaaagaggcc ttaatttaga ggaaggaact
    42901 cccaactacg acatcaagca gttggctctt gagtgtgcaa ccaaacggat gtatccagat
    42961 gttttatctt acgataagat tgttgacttg acaggatcct tcaaggtgcc tatgggttgc
    43021 cgttctttcc tccaaggatg gaaggatgaa aatggtgtag aagtcaattc aggtcgcatg
    43081 aatctgggtg ttgtgacggt taatctgcct cgtattgctc ttgagtctga aggtgatatg
    43141 aataagttct gggaaatctt caacgagcga atgaatatcg cagaagatgc tcttgtttac
    43201 cgtgtcgaac gcactaaaga ggcgacacca gcaaatgctc ctattcttta tcagtacggt
    43261 gcttttggcc atcgtctagg taaagaagaa agtgttgacc agctctttaa gaatcgtcgt
    43321 gctaccgttt cgctgggcta tatcggcttg tatgaagtag cgacagtttt ctttggtaac
    43381 agctgggaaa gtaatccaga tgctaaggaa ttcacgctag acatcattca cgatatgaaa
    43441 cgccgtgtag aagagtggtc agaccaatat ggctaccatt tctctatcta ctcaacacca
    43501 tccgaaagtc tgacagaccg tttctgtcga ctagatatag acaagtttgg ctctattcct
    43561 gatatcacag acaaggaata ctacaccaac tctttccact acgatgttcg taaaaatcca
    43621 acaccgtttg aaaaattgga ctttgagaaa gtctatccag aagcaggtgc gtcaggtggt
    43681 ttcatccatt attgtgagta tccagtcctt cagcaaaatc caaaggcctt ggaagctgtc
    43741 tgggattatg cttatgaccg tgtaggctat ctaggcacca atactccgat tgaccgttgc
    43801 tacaagtgtg actttgaagg ggattttgaa ccaactgaga gagggtttgc ttgtccaaac
    43861 tgtggcaata gcgaccctaa aacagtagat gtggtgaagc gaacttgtgg ctacctaggt
    43921 aatcctcaag caagaccgat ggtcaacggc cgtcacaagg aaatcgctgc gcgtgtcaaa
    43981 catatgaatg gttcaacgat taaaatagct gggcatcaag taacaaatta gaaagaaatg
    44041 aaatgggaaa atatcaacta gacgataagg ggcgcgcaca agtgacccgt tatcacgaga
    44101 aacactctaa aggtggagct ggtaagaaag aacgcttgct tagcttcaga gaacaatttt
    44161 taaacaagaa caagaaaaaa taaaagtgag agccagctct cgcttttctc atagtgggag
    44221 gtaaggatgg aattacgcag accaagatta gcggataaga aagctgtttt agatatgatg
    44281 acagagtttg aaaaatttca gtcgcctcac gacggcggtt tctgggatac agagaacttt
    44341 gtgtatgaag actggttaga aagcaatcag gaacaggaaa tggggattaa tctgcctgaa
    44401 ggatgggttc ctgcaattca gttagtggct ttttctgaga aaggtcaagc agttggattt
    44461 cttaatctcc ggttgcgcct cagtaacttt ctactagaag aaggtggcca cattggctac
    44521 tccattcgtc catctgaaag aggcaagggt tatgcaaaag agactctccg tcagggcttg
    44581 caagttgcta aggaaaagaa catcaagaaa gctctggtga cctgtagcgt gaataatcct
    44641 gctagcagag cagtcattat agcaaatggt ggaatatttg aggatgctcg caatggagtc
    44701 gagcgttatt ggatagaggt agcgaatgaa taatccaaaa ccacaagaat ggaaaagcga
    44761 ggaacttagt caaggtcgta tcattgacta caaggccttt aactttgtgg acggcgaagg
    44821 cgtgcgtaac tctctctatg tatcaggctg tatgtttcac tgcgagggat gttataatgt
    44881 tgcaacttgg tcttttaatg ctggcattcc ctatacagca gaattagaag agcagatcat
    44941 ggcagatctt gctcagccct atgttcaagg tttgactttg ttgggagggg agccttttct
    45001 taatactggg attctcttgc cacttgttaa gcggattcgg aaggaattgc cagacaagga
    45061 catctggtcc tggaccggct acacttggga agaaatgatg ttggaaactc cagataaact
    45121 ggaattcttg tcactgattg acattcttgt cgatggaaga tatgatcgaa ctaagagaaa
    45181 tcttatgctc cagtttcgag gttcatctaa ccaacgaatt atcgatgtgc aaaaatcgct
    45241 caaaagtggg caagtagtga tttgggacaa gctcaatgac ggaaaagaaa gctatgaaca
    45301 ggtgaagaga gaatgaagaa aaaatgaaga aaaaagactt agtagaccaa ctagtctcag
    45361 agatcgagac ggggaaagtc aggacactgg gaatatacgg tcatggagct tcaggtaaat
    45421 caacctttgc acaggaattg taccaagctt tagattctac tacagtaaat ttgctagaaa
    45481 cagatcccta tatcacctcc ggacgctatt tggtagtacc caaggacgcg ccgaatcaaa
    45541 aggtgacagc cagtctgcca gtggcgcatg aactggagag tttgcagaga gatatccttg
    45601 ccttgcaggc gggtatggat gtcttgacaa ttgaagaacc ttggaaggct agtgaggtct
    45661 tgtctggagc caaaccaatt ttgattgtcg aagggatgtc tgttggtttt ctacccaagg
    45721 aactctttga aaaaaccatc tgtttctaca cggatgagga gaccgaatta aagcgacgcc
    45781 ttgctagaga tacgactgtg agaaatcgct atgcatcctt tatattggct agccatcaga
    45841 tgagacggga gcagtatctg cgatactata aagaaactga gtctaaggcg gatatcttag
    45901 tggaccaatc agaagataaa tttgatgtca agaggactta acttatgtat agaagaaata
    45961 tagaagaaaa tccctaattt tagaaagaaa aagtaggaaa acagtttcat cccaaaaaaa
    46021 cgaaaaaacc taacaaatcc cttgcaatcg caggggattt gtgttattct attatggtgc
    46081 tgtaaattac agccttagtt ttgatgcaag aggttgcgac acgctcggtt gcattgccac
    46141 gcaacaccgc gtcggttttc ttgtggagct agcctattat cttaaataga cgaaaaggag
    46201 aaaaagatgg caaacaaaaa aatccgtatc cgtttgaaag cttacgaaca ccgtacgctt
    46261 gacacagcgg ctgcaaaaat cgtagaatca gctactcgta caggtgcaca agttgcgggt
    46321 ccaataccac ttccaactga acgtagcctc tacacaatca ttcgtgcgac tcacaaatac
    46381 aaagactctc gcgaacaatt tgaaatgcgt acacacaaac gtttgatcga tatcgttaac
    46441 ccaactcaaa aaacagttga tgccttgatg aaattggatc ttccaagtgg tgtaaacgta
    46501 gaaatcaaac tttaatctaa aatataaaag agcagaggct ggtgtttcaa tctaattgaa
    46561 cacgggctaa actcggtgtg aaaaagataa acttcctcgc gtctgctaga cactgtgtca
    46621 gtttcctatt ttcactttga gtttgacgcc ctttgtatct tagacttgag cataaaaaac
    46681 gctcgttaaa aactttttga ataaaaaata tagaaaagga actattttct catgacaaaa
    46741 ggaatcttag ggaaaaaagt gggaatgact caaatcttca ctgaagctgg cgaattgatc
    46801 cctgtaacag ttattgaagc aactccaaac gttgttcttc aagttaaaac tgttgaaaca
    46861 gacggataca acgctatcca agttggtttc gatgacaaac gcgaagtatt gagcaacaaa
    46921 cctgctaaag gacatgtagc gaaagctaac acggctccta agcgcttcat tcgtgaattc
    46981 aaaaacgttg aaggcttgga agttggtgct gaaattacag ttgaaacatt cgcagctgga
    47041 gacgttgttg acgtaactgg tacttctaaa ggtaaaggtt tccaaggtgt tatcaaacgc
    47101 cacggacaat cacgtggacc aatggctcac ggttctcgtt accaccgtcg tccaggttct
    47161 atgggacctg ttgcacctaa ccgcgtattc aaaggtaaaa accttgcagg gcgtatgggt
    47221 ggcgaccgcg taacaattca aaaccttgaa gttgtacaag ttgttccaga aaagaacgtt
    47281 atccttatca aaggtaacgt accaggtgct aagaaatctc ttatcactat caaatcagca
    47341 gttaaagctg gtaaataata aagaaagggg aaatcagtca caatggcaaa cgtaacatta
    47401 tttgaccaaa ctggtaaaga agctggccaa gttgttctta gcgatgcagt atttggtatc
    47461 gaaccaaatg aatcagttgt gtttgatgta atcatcagcc aacgcgcaag ccttcgtcaa
    47521 ggaacacacg ctgttaaaaa ccgctctgca gtatcaggtg gtggacgcaa accatggcgt
    47581 caaaaaggaa ctggacgtgc tcgtcaaggt tctatccgct caccacaatg gcgtggtggt
    47641 ggtgttgtct tcggaccaac tccacgttca tacggctaca aacttccaca aaaagttcgt
    47701 cgcctagctc ttaaatcagt ttactctgaa aaagttgctg aaaacaaatt cgtagctgta
    47761 gacgctcttt catttacagc tccaaaaact gctgaatttg caaaagttct tgcagcattg
    47821 agcatcgatt ctaaagttct tgttatcctt gaagaaggaa atgaattcgc agctctttca
    47881 gctcgtaacc ttccaaacgt gaaagttgca actgctacaa ctgcaagtgt tcttgacatc
    47941 gcaaatagcg acaaacttct tgtcacacaa gcagctatct ctaaaatcga ggaggttctt
    48001 gcataatgaa tttgtatgat gttatcaaaa aacctgtcat cactgaaagc tcaatggctc
    48061 aacttgaagc agggaaatat gtatttgaag ttgacactcg tgcacacaaa cttttgatca
    48121 agcaagctgt tgaagctgct ttcgaaggtg ttaaagttgc caatgttaac acaatcaacg
    48181 taaaaccaaa agctaaacgt gttggacgtt acactggttt tactaacaaa actaaaaaag
    48241 ctatcatcac acttacagct gattctaaag caatcgagtt gtttgctgct gaagctgaat
    48301 aatctaagga ggaaatatcg tgggaattcg tgtttataaa ccaacaacaa acggtcgccg
    48361 taatatgact tctttggatt tcgctgaaat cacaacaagc actcctgaaa aatcattgct
    48421 tgttgcattg aagagcaagg ctggtcgtaa caacaacggt cgtatcacag ttcgtcacca
    48481 aggtggtgga cacaaacgtt tttaccgttt ggttgacttc aaacgtaata aagacaacgt
    48541 tgaagcagtt gttaaaacaa tcgagtacga tccaaaccgt tctgcaaaca tcgctcttgt
    48601 acactacact gacggtgtga aagcatacat catcgctcca aaaggtcttg aagtaggtca
    48661 acgtatcgtt tcaggtccag aagcagatat caaagtcgga aacgctcttc cacttgctaa
    48721 catcccagtt ggtactttga ttcacaacat cgagttgaaa ccaggtcgtg gtggtgaatt
    48781 ggtacgtgct gctggtgcat ctgctcaagt attgggttct gaaggtaaat atgttcttgt
    48841 tcgtcttcaa tcaggtgaag ttcgtatgat tcttggaact tgccgtgcta cagttggtgt
    48901 tgtcggaaac gaacaacatg gacttgtaaa ccttggtaaa gcaggacgta gccgttggaa
    48961 aggtatccgc ccaacagttc gtggttctgt aatgaaccct aacgatcacc cacacggtgg
    49021 tggtgaaggt aaagcaccag ttggtcgtaa agcaccatct actccatggg gcaaacctgc
    49081 tcttggtctt aaaactcgta acaagaaagc gaaatctgac aaacttatcg ttcgtcgtcg
    49141 caacgagaaa taatattaaa ctagtcgctt aagcaactag taaatccgcc agctcggtag
    49201 cgctccatag gagtgcaagc cgctgtggta caacatttaa aggagaaaat ataaaaatgg
    49261 gacgcagtct taaaaaagga cctttcgtcg atgagcattt gatgaaaaaa gttgaagctc
    49321 aagctaacga cgaaaagaaa aaagttatta aaacttggtc acgtcgttca acgatcttcc
    49381 caagtttcat tggttacact attgcagttt atgacggacg taaacacgta cctgtttaca
    49441 tccaagaaga catggtaggc cacaaacttg gtgaatttgc accaactcgt acttacaaag
    49501 gtcacgctgc agacgacaag aaaacacgta gaaaataagg agaacataaa tggcagaaat
    49561 tacttcagct aaagcaatgg ctcgtacagt acgtgtttca cctcgtaaat cacgtcttgt
    49621 tcttgataac atccgtggta aaagcgtagc cgatgcaatc gcaatcttga cattcactcc
    49681 aaacaaagct gctgaaatca tcttgaaagt tttgaactca gctgtagcta acgctgaaaa
    49741 caactttggt ttggataaag ctaatttggt agtatctgaa gcattcgcaa acgaaggacc
    49801 aactatgaaa cgtttccgtc cacgtgcgaa aggttcagct tcaccaatca acaaacgtac
    49861 agctcacatc actgtagctg ttgcagaaaa ataaggaggt aaaatcgtgg gtcaaaaagt
    49921 acatccaatt ggtatgcgtg tcggcatcat ccgtgattgg gatgccaaat ggtatgctga
    49981 aaaagaatac gcggattacc ttcatgaaga tcttgcaatc cgtaaattcg ttcaaaaaga
    50041 acttgctgac gcagcagttt caactattga aatcgaacgc gcagtaaaca aagttaacgt
    50101 ttcacttcac actgctaaac caggtatggt tatcggtaaa ggtggtgcta acgttgatgc
    50161 actccgtgca aaacttaaca aattgactgg aaaacaagta cacatcaaca tcatcgaaat
    50221 caaacaacct gatttggatg ctcaccttgt aggtgaagga attgctcgtc aattggagca
    50281 acgtgttgct ttccgtcgtg cacaaaaaca agcaatccaa cgtgcaatgc gtgctggagc
    50341 taaaggaatc aaaactcaag tatcaggtcg tttgaacggt gcagatatcg cccgtgctga
    50401 aggatactct gaaggaactg ttccgcttca cacacttcgt gcagatatcg attacgcttg
    50461 ggaagaagca gatactacat acggtaaact tggtgttaaa gtatggatct accgtggtga
    50521 agttcttcca gctcgtaaaa acactaaagg aggtaaataa ccaatgttag tacctaaacg
    50581 tgttaaacac cgtcgtgagt tccgtggaaa aatgcgcggt gaagcaaaag gtggaaaaga
    50641 agtagcattc ggtgaatacg gtcttcaagc tacaactagc cactggatca ctaaccgcca
    50701 aatcgaagct gctcgtatcg ccatgactcg ttacatgaaa cgtggtggta aagtttggat
    50761 taaaatcttc ccacacaaat catacactgc taaagctatc ggtgtgcgta tgggatctgg
    50821 taaaggggca cctgaaggtt gggtagcacc agttaaacgt ggtaaagtga tgttcgaaat
    50881 cgctggtgta tctgaagaga ttgcacgtga agcgcttcga cttgctagcc acaaattgcc
    50941 agttaaatgt aaattcgtaa aacgtgaagc agaataagga gaaggcatga aacttaatga
    51001 agtaaaagaa tttgttaaag aacttcgtgg tctttctcaa gaagaactcg cgaagcgcga
    51061 aaacgaattg aaaaaagaat tgtttgaact tcgtttccaa gctgctactg gtcaattgga
    51121 acaaacagct cgcttgaaag aagttaaaaa acaaatcgct cgtatcaaaa cagttcaatc
    51181 tgaagcgaaa taatagacta gggaaggaga aatttcaatg gaacgcaata atcgtaaagt
    51241 tcttgttgga cgtgttgtat ctgacaaaat ggacaagaca atcacagttg tagttgaaac
    51301 aaaacgtaac cacccagtct atggtaaacg tattaactac tctaaaaaat acaaagctca
    51361 tgatgaaaac aatgttgcca aagaaggcga tatcgtacgt atcatggaaa ctcgcccgct
    51421 ttcagctaca aaacgtttcc gtcttgtaga agttgttgaa gaagcggtca tcatctaatc
    51481 aaacctgaaa ggagaaaact gaaatgattc aaacagaaac tcgtttgaaa gtcgcagaca
    51541 acagcggtgc tcgcgaaatc ttgactatca aagttcttgg tggttcagga cgtaaatttg
    51601 caaacatcgg tgatgttatc gtggcatctg taaaacaagc tactcctggt ggtgcggtta
    51661 aaaaaggtga cgttgttaaa gcagttatcg ttcgtactaa atcaggtgct cgtcgtgctg
    51721 atggttcata catcaaattt gacgaaaacg cagcagttat catccgtgaa gacaaaactc
    51781 ctcgcggaac acgtatcttt ggcccagttg cacgtgaatt gcgtgaaggt ggcttcatga
    51841 agatcgtgtc acttgctcca gaagtacttt aatttttagg aacaaactag tcccctagct
    51901 tcaagctagg gtgcccttat gggcgtaaga aaaatcaagg agaaacctaa tgtttgtaaa
    51961 aaaaggcgac aaagttcgcg taatcgctgg taaagataag ggaacagaag ctgttgtcct
    52021 tactgccctt ccaaaagtaa acaaagttat cgttgaaggt gttaacattg ttaagaaaca
    52081 ccaacgtcca actaacgagc ttcctcaagg tggtatcatc gagaaagaag cagctatcca
    52141 cgtatcaaac gttcaagttt tggacaaaaa tggtgtagct ggtcgtgttg gttacaaatt
    52201 tgtagacggt aaaaaagttc gctacaacaa aaaatcaggc gaagtgcttg attaatcacg
    52261 aaggaaagga gaagtataat ggcaaatcgt ttaaaagaaa aatatcttaa tgaagtagtt
    52321 cctgctttga cagaacaatt caactactca tcagtgatgg ctgtgcctaa agtagataag
    52381 attgttttga acatgggtgt tggtgaagct gtatcaaacg ctaaaagcct tgaaaaagct
    52441 gctgaagaat tggcacttat ctcaggtcaa aaaccactta tcactaaagc taaaaaatca
    52501 atcgccggct tccgtcttcg tgaaggtgtt gcgatcggtg caaaagttac ccttcgtggt
    52561 gaacgtatgt acgaattctt ggataaattg gtatcagttt cacttccacg tgtacgtgac
    52621 ttccacggtg ttccaacaaa atcatttgat ggacgcggga actacacact tggtgtgaaa
    52681 gaacaattaa tcttcccaga aatcaacttc gatgacgttg acaaaactcg tggtcttgac
    52741 atcgttatcg taacaactgc taacactgac gaagagtcac gtgcattgct tacaggcctt
    52801 ggaatgcctt ttgcaaaata atataggagg taaatctaat ggctaaaaaa tcaatggtag
    52861 ctagagaggc taaacgccaa aaaattgttg accgttatgc tgaaaaacgt gctgcattaa
    52921 aggcggcagg ggactacgaa ggtttatcta aattacctcg caacgcttca ccgactcgtt
    52981 tacataatcg ttgtagagtt acggggcgtc cacattcagt ttaccgcaaa tttggtctga
    53041 gtcgtatcgc ttttcgcgaa cttgcgcata aaggtcaaat tcctggtgta acaaaagcat
    53101 cttggtaatt taagatatca agggcgtcaa aactccaagt aaaaatagga aacttgacga
    53161 agaaactaaa gtttctagga aagtttatct ttttcacaca gagtttagcc cgggttcaat
    53221 tgggcttgcc aatttgaaca cgagctacag ctttggcaaa aaagaccaat ttgctttgga
    53281 gcattgcttc tgcattaaat tgtctatttt tgctcgtgct gttacgctct ttgtatcatg
    53341 tattaactag caagtgcaac ttgcaaacta ctagtaagag gagaaaaaca aaatggttat
    53401 gactgaccca atcgcagact tcctaactcg tattcgtaat gctaaccaag ctaaacacga
    53461 agtacttgaa gtacctgcat caaacatcaa aaaagggatt gctgaaatcc ttaaacgcga
    53521 aggttttgta aaaaacgttg aaatcatcga agatgacaaa caaggcgtca tccgtgtatt
    53581 tcttaaatac ggaccaaatg gtgaaaaagt tatcactaac ttgaaacgtg tttctaaacc
    53641 aggacttcgt gtctacaaaa aacgtgaaga ccttccaaaa gttcttaacg gacttggaat
    53701 tgccatcctt tcaacttctg aaggtttgct tactgataaa gaagcacgcc aaaagaatgt
    53761 tggtggtgag gttatcgctt acgtttggta aaatcaagat acaaagctcg taaagaacaa
    53821 agcaaaatta ggaagttgga gaagtttgtt tacaaacaag ccaacttatc tattttgcac
    53881 agttcttaga gcgtgttcag ttcagctttt gaactaaata agtatctgaa ccccgtgaaa
    53941 actggccgtt ttggcctgac aatttaacag gagaaaataa acatgtcacg tattggtaat
    54001 aaagttatcg tgttgcctgc tggtgttgaa ctcgctaaca atgacaacgt tgtaactgta
    54061 aaaggaccta aaggagaact tactcgtgag ttctcaaaag atattgaaat ccgtgtggaa
    54121 ggtactgaag taactcttca ccgtccaaac gattcaaaag aaatgaaaac tatccacgga
    54181 actactcgtg cccttttgaa caacatggtt gttggtgtat cagaaggatt caagaaagaa
    54241 cttgaaatgc gtggggttgg ttaccgtgca cagcttcaag gatctaaact tgttttggct
    54301 gttggtaaat ctcatccaga cgaagttgaa gctccagaag gaattacttt tgaacttcca
    54361 aacccaacaa caatcgttgt tagcggaatt tcaaaagaag tagttggtca aacagctgct
    54421 tacgtacgta gccttcgttc accagaacca tataaaggta aaggtatccg ttacgttggt
    54481 gaattcgttc gccgtaaaga aggtaaaaca ggtaaataat gttgagtggt tgatcatcaa
    54541 ccaccaacct attttccaac tttgtgcata gcacacgatt taaaactaaa gaggtgaaaa
    54601 ctgtgatttc aaaaccagat aaaaacaaac tccgccaaaa acgccaccgt cgcgttcgcg
    54661 gaaaactctc tggaactgct gatcgcccac gtttgaacgt attccgttct aatacaggca
    54721 tctacgctca agtgattgat gacgtagcgg gtgtaacgct cgcaagtgct tcaactcttg
    54781 ataaagaagt ttcaaaagga actaaaactg aacaagccgt tgctgtcggt aaactcgttg
    54841 cagaacgtgc aaacgctaaa ggtatttcag aagtggtgtt cgaccgcggt ggatatctat
    54901 atcacggacg tgtgaaagct ttggctgatg cagctcgtga aaacggattg aaattctaat
    54961 aggaggacac tagaaaatgg catttaaaga caatgcagtt gaattagaag aacgcgtagt
    55021 tgctgtcaac cgtgttacaa aagttgttaa aggtggacgt cgtcttcgtt tcgcagctct
    55081 tgttgttgtt ggtgaccaca atggtcgcgt aggatttggt actggtaaag ctcaagaagt
    55141 tccagaagca atccgtaaag cagtagatga tgctaagaaa aacttgatcg aagttcctat
    55201 ggttggaaca acaatcccac acgaagttct ttcagaattc ggtggagcta aagtattgtt
    55261 gaaacctgct gtagaaggtt ctggagttgc cgctggtggt gcagttcgtg ccgttgtgga
    55321 attggcaggt gtggcagata ttacatctaa atcacttggt tctaacactc caatcaacat
    55381 tgttcgtgca actgttgaag gtttgaaaca attgaaacgc gctgaagaaa ttgctgccct
    55441 tcgtggtatt tcagtttctg atttggcata agaaagggga taaaatggct caaattaaaa
    55501 ttactttgac taagtctcca atcggacgca ttccatcaca acgtaaaact gttgtagcac
    55561 ttggacttgg caaattgaac agctctgtta ttaaagaaga taacgctgct atccgtggta
    55621 tgattacagc agtatctcac ttagtaacag ttgaagaagt aaactaatga agttttaggg
    55681 gatgtgcact gtaccatccc ctaaaactag atatagtcat ctatgatgac atcgtatagg
    55741 cgagttgatg ggggagacaa ccttttctcc cttatcggcg ctagcatttt acaaaagagg
    55801 agaaaataaa aatgaaactt catgaattga aacctgcaga aggttctcgt aaagtacgta
    55861 accgcgttgg tcgtggtact tcatcaggta acggtaaaac atctggtcgt ggtcaaaaag
    55921 gtcaaaaagc tcgtagcggt ggcggagttc gccttggttt tgaaggtgga caaactccat
    55981 tgttccgtcg tcttccaaaa cgtggattca ctaacatcaa cgctaaagaa tacgcaattg
    56041 tgaaccttga ccaattgaac gtctttgaag atggtgctga agtaactcca gttgttctta
    56101 tcgaagcagg aattgttaaa gctgaaaagt caggtattaa aattcttggt aacggtgagt
    56161 tgactaagaa attgactgtg aaagcagcta aattctctaa atcagctgaa gaagctatca
    56221 ctgctaaagg tggttcagta gaagtcatct aagagaggtg acctatgttt tttaaattat
    56281 taagagaagc tcttaaagtc aagcaggttc gatcaaaaat tttatttaca atttttatcg
    56341 ttttggtctt tcgtatcgga actagcatta cagttcctgg tgtgaatgcc aatagcttga
    56401 atgctttaag tggattatcc ttcttaaaca tgttgagctt ggtgtcgggg aatgccctaa
    56461 aaaacttttc gatttttgcc ctaggagtta gtccctatat caccgcttct attgttgtcc
    56521 aactcttgca aatggatatt ttacccaagt ttgtagagtg gggtaaacaa ggggaagtag
    56581 gtcgaagaaa attgaatcaa gctactcgtt atattgctct agttctcgct tttgtgcaat
    56641 ctatcgggat tacagctggt tttaatacct tggctggagc tcaattgatt aaaactgctt
    56701 taactccaca agtttttctg acgattggta tcatcttaac agctggtagt atgattgtca
    56761 cttggttggg tgagcaaatt acagataagg gatacggaaa cggtgtttcc atgattatct
    56821 ttgccgggat tgtttcctca attccagaga tgattcaggg catctatgtg gactactttg
    56881 tgaacgtccc aagtagccgt atcacttcat ctatcatttt cgtaatcatt ttgattatta
    56941 ctgtattgtt gattatttac tttacaactt atgttcaaca agcagaatac aaaattccaa
    57001 tccaatatac taaggttgca caaggtgctc catctagctc ttaccttccg ttaaaggtaa
    57061 accctgctgg agttatccct gttatctttg ccagttcgat tactgcagcg cctgcggcta
    57121 ttcttcagtt tttgagtgcc acaggtcatg attgggcttg ggtaagggta gcacaagaga
    57181 tgttggcaac tacttctcca actggtattg ccatgtatgc tttgttgatt attctcttta
    57241 cattcttcta tacgtttgta cagattaatc ctgaaaaagc agcagagagc ctacaaaaga
    57301 gtggtgccta tatccatgga gttcgtcctg gtaaaggtac agaagaatat atgtctaaac
    57361 ttcttcgtcg tcttgcaact gttggttccc tcttccttgg tgtgatttcc attttaccga
    57421 ttgcagctaa agatgtattt ggtctttctg atgttgttgc ctttggtgga acaagtctct
    57481 tgatcattat ctctacaggt atcgaaggaa tcaagcaatt ggaaggttac ctattgaaac
    57541 gtaagtatgt tggtttcatg gacagaacag aataaaagta tttactgaat cagtaaatac
    57601 tgagggagtg gaggtttaaa ctctgacatt tgtaagagtt ggatctcccc tcttctattt
    57661 tgtttttaaa taggggtgaa aagacttttt gcttctattt aaaaataaaa taaggagatc
    57721 aaatcatgaa tcttttgatt atgggcttac ctggtgcagg taagggaact caagcagcaa
    57781 aaatcgtaga acaattccat gttgcacata tctcaacagg tgatatgttc cgcgctgcaa
    57841 tggcaaatca aactgaaatg ggtgttcttg ctaagtcata tattgacaag ggtgaattgg
    57901 ttcctgacga agttacaaat ggaatcgtaa aagaacgcct ttcacaagat gatattaaag
    57961 aaacaggatt cttattggat ggttacccac gtacaattga acaagctcat gccttggaca
    58021 aaacattggc tgaacttggc attgaactag aaggtattat caatattgaa gtgaaccctg
    58081 acagcctctt ggaacgtttg agtggccgta tcatccaccg cgtaactgga gaaactttcc
    58141 acaaggtctt taacccacca gttgactata aagaagaaga ttactaccaa cgtgaagatg
    58201 ataagcctga gacagtaaaa cgtcgtttgg atgttaatat tgctcaagga gaaccaatca
    58261 ttgctcacta ccgtgccaaa ggtttggttc atgacatcga aggtaatcaa gatatcaatg
    58321 atgtcttctc agatattgaa aaagtattga caaatttgaa ataaagcgtt tttcgcactt
    58381 gcaaaaatcc gctacaaatg ttatactgag atagtctgac ttataattgt tgtctctgtg
    58441 tctagaggca tcgaatcgaa atttatggag gtgcttttgc gtggcaaaag acgatgtgat
    58501 tgaagttgaa ggcaaagtag ttgatacaat gccgaatgca atgtttacgg ttgaacttga
    58561 aaatggacat cagattttag caacagtttc tggtaaaatt cgtaaaaact atattcgtat
    58621 tttagcggga gatcgtgtta ctgtcgaaat gagtccatat gacttgacac gtggacgtat
    58681 cacttaccgc tttaaataat cgaaaaactt ggagggataa gaaatgaaag taagaccatc
    58741 ggtcaaacca atttgcgaat actgtaaagt tattcgtcgt aatggtcgtg ttatggtaat
    58801 ttgcccagca aatccaaaac acaaacaacg tcaaggataa gatagaaagg agaaaacatg
    58861 gctcgtattg ctggagttga tattccaaat gacaaacgcg tagtaatctc attgacttat
    58921 gtttatggta tcggacttgc aacatctaag aaaattttgg ctgctgctgg aatctcagaa
    58981 gatgttcgtg tacgtgatct tacatcagat caagaagatg ctatccgtcg tgaagtggat
    59041 gcaatcaaag ttgaaggtga ccttcgtcgt gaagtaaact tgaacatcaa acgtttgatg
    59101 gaaatcggtt cataccgtgg tatccgtcac cgtcgtggac ttcctgtccg tggacaaaac
    59161 actaaaaaca acgctcgcac tcgtaaaggt aaagctgttg cgattgctgg taagaaaaaa
    59221 taatatagga ggtaaaagtc ttggctaaac caacacgtaa acgtcgtgtg aaaaagaata
    59281 tcgaatctgg tattgctcat attcacgcta catttaataa cactattgtt atgattactg
    59341 atgtgcatgg taatgcaatt gcttggtcat cagctggtgc tcttggtttc aaaggttctc
    59401 gtaaatctac accattcgct gctcaaatgg cttctgaagc tgctgctaaa tctgcacaag
    59461 aacacggtct taaatcagtt gaagttactg taaaaggtcc aggttctggt cgtgagtcag
    59521 ctattcgtgc gcttgctgcc gctggtcttg aagtaacagc aattcgtgat gtgactccag
    59581 tgccacacaa tggtgctcgt cctccaaaac gtcgccgtgt ataatcatcg cattacactg
    59641 cttttcgttt aagagggagt aactaaatga tcgagtttga aaaaccaaat ataacaaaaa
    59701 ttgatgaaaa taaagattat ggcaagtttg taatcgaacc acttgaacgt ggctacggta
    59761 caactcttgg taactctctt cgtcgtgtac ttctagcttc tctaccagga gcagctgtga
    59821 catctatcaa cattgatggt gtgttacatg agtttgacac agttccaggt gttcgtgaag
    59881 acgtgatgca aatcattctg aacattaaag gaattgcagt gaaatcgtac gttgaagacg
    59941 aaaaaatcat cgaactggat gttgaaggtc ctgctgaagt aacagctggt gacattttga
    60001 cagatagcga tattgaaatt gtaaatccag atcattatct ctttacaatc ggtgaaggtt
    60061 cttctctaaa agcgactatg actgttaaca gtggtcgtgg atatgtacct gctgatgaaa
    60121 ataaaaagga taatgcacca gttggaacac ttgctgtaga ttctatttat acaccagtta
    60181 caaaagtcaa ctatcaagtg gaacctgctc gtgtaggtag caatgatggt ttcgacaaat
    60241 taacccttga aatcttgaca aatggaacaa ttattccaga agatgcttta gggctttcag
    60301 cacgtatttt gacagaacat cttgatttgt ttacaaatct tactgagatt gctaagtcaa
    60361 ctgaagtgat gaaagaagct gatactgaat ctgacgaccg tattttagat cgtacgattg
    60421 aggaactgga cttgtctgtg cgttcataca actgtttaaa acgtgccggt atcaatactg
    60481 tgcatgattt gacagaaaaa tctgaagcag agatgatgaa agtacgaaat cttggacgca
    60541 agagtttgga agaagtgaaa ctcaaactca ttgatttggg tcttggatta aaagataaat
    60601 aaaggaggaa tacatggctt accgtaaact aggacgcact agctcacaac gtaaagcaat
    60661 gcttcgcgat ttgacaactg accttttgat caacgaatca atcgtgacaa ctgaagctcg
    60721 tgctaaagaa atccgtaaaa ctgttgaaaa aatgattact ctaggtaaac gtggtgattt
    60781 gcatgcacgt cgtcaagcag ctgctttcgt acgtaatgaa atcgcatctg aaaactatga
    60841 tgaagcaact gataagtaca cttctactac agcacttcaa aaattgttct cagaaatcgc
    60901 acctcgttat gctgaacgta acggtggata cactcgtatc cttaaaactg aaccacgtcg
    60961 tggtgatgca gcgccaatgg cgatcatcga attagtataa aatcatcaat tttgttgagt
    61021 gttatgatga tggagtcttg tgctcttagt ctagctctgg tctaccgcta ggatttcggt
    61081 cctagcggga acactcatca taagttggga tagtagacgc ttgtttacga aattgttttt
    61141 ttcttaagaa caacttcgta agcaggcgtt tttgagtatt ttcgttagaa ttatgctata
    61201 ctatttgaaa agaatcctgt ttaatgttaa ggtttcttat tttaagaaga attggagttt
    61261 acttatgaaa gccattataa ctgttgttgg taaagataaa tctggaattg ttgcaggtgt
    61321 ttctggtaaa attgcagaat taggattgaa tattgacgat atctctcaaa ctgtcttgga
    61381 tgaatatttt acgatgatgg ctgttgtatc tagtgatgaa aagcaagatt ttacctatct
    61441 tcgtaatgaa tttgaagctt ttgggcaaac tttgaatgta aaaatcaata ttcagagtgc
    61501 agcgattttc gaagctatgt ataatatcta ggaggttatc atggatatta gacaagttac
    61561 tgaaaccatc gccatgattg aggagcaaaa tttcgatatc agaaccatta ccatggggat
    61621 ttctcttttg gattgtatcg atccagatat caatcgtgct gcggagaaaa tctatcaaaa
    61681 aattacgaca aaggcggcta atttagtagc tgttggtgat gaaattgcgg ctgagttggg
    61741 aattcctatc gttaataagc gtgtatcggt gacacctatt tctctgattg gggcagcgac
    61801 agatgcgacg gactacgtgg ttctggcaaa agcgcttgat aaggctgcga aagagattgg
    61861 tgtggacttt attggtggtt tttctgcctt agtacaaaaa ggttatcaaa agggagatga
    61921 gattctcatc aattccattc ctcgcgcttt gactgagacg gataaggtct gctcgtcagt
    61981 caatatcggc tcaaccaagt ctggtattaa tatgacggct gtggcagata tgggacgaat
    62041 tatcaaggaa acggcaaatc tttcagatat gggagcggcc aagttggttg tattcgctaa
    62101 tgctgttgag gacaatccat ttatggcggg tgcctttcat ggtgttgggg aagcagatgt
    62161 tatcatcaat gtcggagttt ctggtcctgg tgtggtgaaa cgtgctttgg aaaaagttcg
    62221 tggacagagc tttgatgtag tagccgaaac agttaagaaa actgccttta aaatcactcg
    62281 tatcggtcaa ttggttggtc aaatggccag tgagagactg ggtgtggagt ttggtattgt
    62341 ggacttgagt ttggcaccaa cccctgcggt tggagactct gtggcacgtg tccttgagga
    62401 aatggggcta gaaacagttg gcacgcatgg aacgacagct gccttggccc tcttgaacga
    62461 ccaagttaaa aagggtggag tgatggcctg taatcaggtc ggtggtctat ctggtgcctt
    62521 tatccctgtt tctgaggatg aaggaatgat tgctgcagtg caaaatggct ctcttaattt
    62581 agaaaaacta gaagctatga cggctatctg ttctgttgga ttggatatga ttgccatccc
    62641 agaagatacg cctgctgaaa ctattgcggc tatgattgcg gatgaagcag caatcggtgt
    62701 tatcaacatg aaaacaacag ctgttcgtat cattcccaaa ggaagagaag gcgatatgat
    62761 tgagtttggt ggtctattag gaactgcacc cgttatgaag gttaatgggg cttcgtctgt
    62821 cgacttcatc tctcgcggtg gacaaatccc agcaccaatt catagtttta aaaattaaga
    62881 aaataggaga aattttaagt tct
//
LOCUS       DAVLBE010000006        58029 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.006, whole genome shotgun sequence.
ACCESSION   DAVLBE010000006 DAVLBE010000000
VERSION     DAVLBE010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 58029)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 58029)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..58029
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.006"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            226..507
                     /locus_tag="VXB91_000383"
     CDS             226..507
                     /locus_tag="VXB91_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HEV0469895.1"
                     /translation="MDTPDENGYVADDYRITYLEAHIKAMRDAIYKDGVDLLGYTTWG
                     CIDSVSAGTGEMNKRYGFIYVDRDNVGNGTLKRSKKKSFYWYMSFIAMV"
     gene            639..1583
                     /gene="manA"
                     /locus_tag="VXB91_000384"
     CDS             639..1583
                     /gene="manA"
                     /locus_tag="VXB91_000384"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HEV0469896.1"
                     /translation="MSEPLFLQSVMQEKIWGGTKLRDEFGYDIPSEKVGEYWAISAHL
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDALLTKVPVKAG
                     DFFYVPSGTMHAIGAGILILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTIKADDLRSTLLVSNDFFAVYKWEITGKVNFEKTADYSLLSVLAGQGQL
                     TVDGKNYPIQKGRHFILPSDVEAWTLEGQDLELIVSHP"
     gene            complement(1605..3080)
                     /locus_tag="VXB91_000385"
     CDS             complement(1605..3080)
                     /locus_tag="VXB91_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
                     /protein_id="HEV0469897.1"
                     /translation="MVFLTDLRKHNRIVKSINQTEGYLTTQVAFSYFEKGDQSLTMSE
                     KSQWGSKLGFILASAGSVIGLGSVWKFPYMTAANGGGGFLLIFLISTILIGFPLLLAE
                     FALGRSAGVSAIKTFGKLGKNNKYNFIGWIGAFALFILLSFYSVIGGWILVYLGIEFG
                     KLFQLGGTGDYAQLFTSIISNPAIALGAQAAFILLNIFIVSRGVQKGIERASKVMMPL
                     LFIIFVVIIGRSLSLPNAMEGVLYFLKPDFSKLTSAGLLYALGQSFFALSLGVTVMLT
                     YASYLDKKTNLVQSGISIVAMNISISIMAGLAIFQARSPFNIQSEGGPSLLFIVLPQL
                     FDKMPFGTIFYVLFLFATVTSSVVMLEINVGNITNQDNSKRAKWSVILGILTFVFGIP
                     SALSYGVMADVHIFGKTFFDAMNFLVPNLLMPFGALYLSLFTGYIFKKALAMEELHLD
                     ERAWKQGLFQVWLFLLRFFVPSFQSSSWSSSPNLCNQKGLE"
     gene            3246..3410
                     /locus_tag="VXB91_000386"
     CDS             3246..3410
                     /locus_tag="VXB91_000386"
                     /inference="COORDINATES: protein motif:HMM:NF024803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEV0469898.1"
                     /translation="MVPLKSENGYRTYSQEDLERLQVILYYKYLGFSLEKIAELLKEE
                     RTDLLLHLTR"
     gene            3411..3917
                     /locus_tag="VXB91_000387"
     CDS             3411..3917
                     /locus_tag="VXB91_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000386122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TipAS antibiotic-recognition domain-containing
                     protein"
                     /protein_id="HEV0469899.1"
                     /translation="MDYLTRERQHLDTLISTLQKTIQEQKGERKMTIEEKFTGFSYQD
                     NQKYHQEAVEKYGQEVMGQALERQKGHEDEATAAFNQVFQTLAQNLQVGLPATATENQ
                     EQAAKLLQAIRTYGFDCSIEVFGHIGKGYVYNPEFKENIDKFGSETAQYTSDAIAAYV
                     QTNAEKIG"
     gene            complement(3937..4392)
                     /locus_tag="VXB91_000388"
     CDS             complement(3937..4392)
                     /locus_tag="VXB91_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEV0469900.1"
                     /translation="MNRREAVEFVNMCMIKNGDKVLVQDRVSPDWSGITFPGGHVERG
                     ESFVDAVIREVKEETGLIISKPQLCGIKNWYDDKDYRYVVLFYKTEHFTGELQSSDEG
                     KVWWEDFENLSHLKLATDDMSDMLRVFLEEDLSEFFYYKNGDDWLYDLK"
     gene            complement(4412..5587)
                     /locus_tag="VXB91_000389"
     CDS             complement(4412..5587)
                     /locus_tag="VXB91_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEV0469901.1"
                     /translation="MKHFDTIVIGGGPAGMMATISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELGGQVATQIEIVSVKKVDDQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTITDLEAAESPLLTDFPHKALQGISLDDVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSFVKGGEVLSLDVLPQLSEKDLVTFLEENREKS
                     LKNALKTLLPERLAEFFVQGYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFTGEVMDINAHTGGFNITSALCTGWVAGSLHYD"
     gene            complement(5646..6491)
                     /locus_tag="VXB91_000390"
     CDS             complement(5646..6491)
                     /locus_tag="VXB91_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEV0469902.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYNE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEEGGLLM
                     GYEID"
     gene            6616..7173
                     /locus_tag="VXB91_000391"
     CDS             6616..7173
                     /locus_tag="VXB91_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEV0469903.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            7192..7659
                     /locus_tag="VXB91_000392"
     CDS             7192..7659
                     /locus_tag="VXB91_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HEV0469904.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            7748..8377
                     /gene="upp"
                     /locus_tag="VXB91_000393"
     CDS             7748..8377
                     /gene="upp"
                     /locus_tag="VXB91_000393"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HEV0469905.1"
                     /translation="MGKIEVINHPLIQHKLSILRRTDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRDEETLQPVEYLVKLPEDIDQRQIFIVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            8551..9141
                     /gene="clpP"
                     /locus_tag="VXB91_000394"
     CDS             8551..9141
                     /gene="clpP"
                     /locus_tag="VXB91_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HEV0469906.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN"
     gene            9220..9468
                     /locus_tag="VXB91_000395"
     CDS             9220..9468
                     /locus_tag="VXB91_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HEV0469907.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            9569..10729
                     /locus_tag="VXB91_000396"
     CDS             9569..10729
                     /locus_tag="VXB91_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV0469908.1"
                     /translation="MKKKFALSFVALASVALLAACGEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVVDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTKMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKDNLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEAAEVVKP"
     gene            10997..11866
                     /locus_tag="VXB91_000397"
     CDS             10997..11866
                     /locus_tag="VXB91_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEV0469909.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGPISLTNVQLMILAISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFGMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            11870..12826
                     /locus_tag="VXB91_000398"
     CDS             11870..12826
                     /locus_tag="VXB91_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEV0469910.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKLPTYGAFFGAMLVGALLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            12826..13590
                     /locus_tag="VXB91_000399"
     CDS             12826..13590
                     /locus_tag="VXB91_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0469911.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKAKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            13590..14300
                     /locus_tag="VXB91_000400"
     CDS             13590..14300
                     /locus_tag="VXB91_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0469912.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKMPAQKIVAGGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQGTTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            14714..15370
                     /locus_tag="VXB91_000401"
     CDS             14714..15370
                     /locus_tag="VXB91_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEV0469913.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQGLHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKISILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIVSL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDGSIDLPALKEKFEANGIQVEEIARTSAKVL
                     "
     gene            15478..16573
                     /gene="prfB"
                     /locus_tag="VXB91_000402"
     CDS             join(15478..15549,15551..16573)
                     /gene="prfB"
                     /locus_tag="VXB91_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HEV0469914.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQEKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSFEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            16591..17283
                     /gene="ftsE"
                     /locus_tag="VXB91_000403"
     CDS             16591..17283
                     /gene="ftsE"
                     /locus_tag="VXB91_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HEV0469915.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDIPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKRRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            17276..18202
                     /locus_tag="VXB91_000404"
     CDS             17276..18202
                     /locus_tag="VXB91_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0469916.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLKV"
     gene            18488..20668
                     /locus_tag="VXB91_000405"
     CDS             18488..20668
                     /locus_tag="VXB91_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEV0469917.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFAPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDASQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEA
                     QQNTVHFKDLTEEVYSVADGQVVALEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVAAGDLLVTADL
                     DAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            20720..21535
                     /locus_tag="VXB91_000406"
     CDS             20720..21535
                     /locus_tag="VXB91_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEV0469918.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLLEQGKNYYWTWAYNHIGYDRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETVVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAILNWK"
     gene            21675..23018
                     /locus_tag="VXB91_000407"
     CDS             21675..23018
                     /locus_tag="VXB91_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV0469919.1"
                     /translation="MSFTKFQFKNYIREALKELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLASNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLETVDKIAGSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDKNAQIYQLTQLMQPYLAMIFVNTKTRADELHSYLTAQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
     gene            23234..24424
                     /locus_tag="VXB91_000408"
     CDS             23234..24424
                     /locus_tag="VXB91_000408"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HEV0469920.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRL
                     AELRKSEEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVIKK
                     VIKEVIPSSYLDDKTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAADLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            24977..25912
                     /locus_tag="VXB91_000409"
     CDS             24977..25912
                     /locus_tag="VXB91_000409"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HEV0469921.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
     gene            25946..26983
                     /locus_tag="VXB91_000410"
     CDS             25946..26983
                     /locus_tag="VXB91_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEV0469922.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQVLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNPSPTTKLIIFAEGKLDSKRRLVKLLKRDAKVFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKANSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            27156..27761
                     /locus_tag="VXB91_000411"
     CDS             27156..27761
                     /locus_tag="VXB91_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HEV0469923.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELTAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            27918..28448
                     /locus_tag="VXB91_000412"
     CDS             27918..28448
                     /locus_tag="VXB91_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HEV0469924.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCAYFVLENEAPKRVSFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKEQRHFVIRQK"
     gene            28469..29371
                     /locus_tag="VXB91_000413"
     CDS             28469..29371
                     /locus_tag="VXB91_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S rRNA methyltransferase"
                     /protein_id="HEV0469925.1"
                     /translation="MKPSIHSLAHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQRIVQESADGTVKYLFELPDGMLIETVLMRQHYGLS
                     VCVTTQVSCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFADEGVQVNLAVSLHA
                     PNNELRSSIMKINRAFPIEKLFAAIEYYIETTNRRVTFEYIMLNEVNDGVEQALELAE
                     LLKNIKKLSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGGNCVVRQEHGTDID
                     AACGQLRFNTMKRDRQKAVAAVNP"
     gene            29371..29853
                     /locus_tag="VXB91_000414"
     CDS             29371..29853
                     /locus_tag="VXB91_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEV0469926.1"
                     /translation="MMKKTYNHILVWGVIFYSICIVYFCFTPQEQSTVGVGTPDIQPL
                     GRLVFLLTPFNSLWKLGEVSDIGQLCWIFLQNILNVFLFFPLIFQLLYLFPNLRKTKK
                     VLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKIRN
                     "
     gene            29855..31396
                     /locus_tag="VXB91_000415"
     CDS             29855..31396
                     /locus_tag="VXB91_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV0469927.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMEMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGIMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQAKNLQIGY
                     DRPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHEPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(31452..32255)
                     /locus_tag="VXB91_000416"
     CDS             complement(31452..32255)
                     /locus_tag="VXB91_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEV0469928.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGDGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQNSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIDGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS"
     gene            complement(32339..32552)
                     /locus_tag="VXB91_000417"
                     /pseudo
     CDS             complement(32339..32552)
                     /locus_tag="VXB91_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(33031..33240)
                     /locus_tag="VXB91_000418"
     CDS             complement(33031..33240)
                     /locus_tag="VXB91_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0469929.1"
                     /translation="MLSVNTILEKFYKEHQVKPFISPERELDTWLLSPKPVPKRNMDL
                     LVDDSLAGDIILLWRIQFGTFTTET"
     gene            33410..33682
                     /gene="rpsP"
                     /locus_tag="VXB91_000419"
     CDS             33410..33682
                     /gene="rpsP"
                     /locus_tag="VXB91_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HEV0469930.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            33702..33941
                     /locus_tag="VXB91_000420"
     CDS             33702..33941
                     /locus_tag="VXB91_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HEV0469931.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
     gene            34518..35306
                     /locus_tag="VXB91_000421"
     CDS             34518..35306
                     /locus_tag="VXB91_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEV0469932.1"
                     /translation="MKRFEVSTEIGSLSVTYQKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIHDQAGKNLDNLADAVYEVLEELGISEYILCAHSWSGI
                     LACKLLEKPIKRQTLVAIEPTTKKVMFADFSENPYPKMEEQMRLIDECGPELYFKNLT
                     QATFSPETNKKIWELMQEKGLELENQDPEFQISGEITEEDFENLSIESHVPVFIFCQT
                     YREKEYRESEYWTSNTKLILGGNHHYLQWSESEKIAAIIRELSE"
     gene            35337..35855
                     /gene="rimM"
                     /locus_tag="VXB91_000422"
     CDS             35337..35855
                     /gene="rimM"
                     /locus_tag="VXB91_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HEV0469933.1"
                     /translation="MNYFNIGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELALFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKGYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            35845..36564
                     /gene="trmD"
                     /locus_tag="VXB91_000423"
     CDS             35845..36564
                     /gene="trmD"
                     /locus_tag="VXB91_000423"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HEV0469934.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDDPYGGGQGMLLRAQPIFDSFDAIEKKNPRVILLDPAGKQFDQAYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            36576..36914
                     /locus_tag="VXB91_000424"
     CDS             36576..36914
                     /locus_tag="VXB91_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0469935.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(36945..37265)
                     /locus_tag="VXB91_000425"
     CDS             complement(36945..37265)
                     /locus_tag="VXB91_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0469936.1"
                     /translation="MRHKFQQVLDKIHDFLNGHDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFAKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            37363..37578
                     /locus_tag="VXB91_000426"
     CDS             37363..37578
                     /locus_tag="VXB91_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HEV0469937.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            complement(37647..37733)
                     /locus_tag="VXB91_000427"
                     /pseudo
     CDS             complement(37647..37733)
                     /locus_tag="VXB91_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(37784..38320)
                     /locus_tag="VXB91_000428"
     CDS             complement(37784..38320)
                     /locus_tag="VXB91_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HEV0469938.1"
                     /translation="MKKAHVYAIPAIGAALIAVLAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALVVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQAYFTN"
     gene            38746..39084
                     /locus_tag="VXB91_000429"
     CDS             38746..39084
                     /locus_tag="VXB91_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0469939.1"
                     /translation="MKKRINKKASVFLVASVFSFSFATTASVVNAVTAHPAPSPIIDV
                     WEYGVNDNYGYSNYFVSSPSNIGSKSSVTNFWGTVKAQDKKDYGWAYSSATKSWNDVR
                     LNAYWDYYRF"
     gene            39150..41132
                     /locus_tag="VXB91_000430"
     CDS             39150..41132
                     /locus_tag="VXB91_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0469940.1"
                     /translation="MKLKLCIIGFFFCLIATIGLVTISDTEIPIPLPIDGAFSIQGKS
                     NLSNNEIYEMVRDLSKTEKVTIYKPIVQSSGQLKYVNFDDVNNEQLKSAPIVGMYYTL
                     GKMDVDSLKPLTMTGLQTVYMAYPWYIGGILQFTGTLRILLMGSIYLTLLVVLFVVRT
                     RQIKEGVIRRSLGLPIYDLRREYGISLIFELIMMALLMISYSSFLGNGFFTYSSKLFF
                     SLLLTNFILFQIIDLITFVLFWLTIQIEKPIEIIKNKAKNKLIFVVWLAIISIIILVS
                     GVFLQETKSSQSSINIQIQNLVPWDTVKDWRRIEFLGIESNSTKNREVNDSDGQYLQI
                     VAALKNLDFLYIERSSAYVPDFMKTSHVIENFSKQLENDGITNPEINKELIYINQTGA
                     NLQNKVNGTNYHLLDNKIATIYIPEKWKENQKSIENTVVAEQFIGTNYTREQLAVQII
                     PDGEKIFYFNEDADNNLKMKDILPLANVADSKDNIVVVLDTDKMMENNKFSLASNILY
                     KSLFSPEAVKKINEMTVLLNFSMNPVDVYQIVKLKIQSLEHQILLSQILQKIIYSIVF
                     ILIYQYVQLFITLKQNEYVKKIILGLSKTYIAISSLKYFMMTITMVILFTFLMTGQIE
                     LLYIGAASLLVLMLSIIMSFRKLSESYTKILKGDES"
     gene            41129..41752
                     /locus_tag="VXB91_000431"
     CDS             41129..41752
                     /locus_tag="VXB91_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0469941.1"
                     /translation="MTIDLLNVSKSFGSKKIFTDLNLIFESGKSYALIGGSGSGKSTL
                     LNIIGRLEKIDSGNVLVDKQDIWKIKERTFFKNTVGYVFQNYSLIDNKTVYDNLSLIT
                     KDKKTITDVLEKVGLSSDYLHQKIYELSGGQAQRVAIARMLMKPCKIILADEPTGALD
                     GEIGKEIIRLLLNETAEDKYVIIATHDPAVYNEVDVIIDMKDIGYKV"
     gene            41749..42249
                     /locus_tag="VXB91_000432"
     CDS             41749..42249
                     /locus_tag="VXB91_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0469942.1"
                     /translation="MKKKIYIALIFVTGVLAIFFFGKQMITKENINKPTVELTIYTLS
                     SSDTEKWNKVRQVETEEAIYFITVKEVSSSEEVFSNIIANGAATGFGVREEEVKKFNN
                     GLGDTIEDSKHNKLIEIEFFTFSDDGAGFVVANFDYGKEELNSQKKDIKELYKKIYES
                     FKEKNK"
     gene            complement(42415..43761)
                     /gene="gor"
                     /locus_tag="VXB91_000433"
     CDS             complement(42415..43761)
                     /gene="gor"
                     /locus_tag="VXB91_000433"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HEV0469943.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGAKAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFDFATLRRNREAYIDRARSSYDGSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESIAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RTNLPLHTHKVPVKLEKTTDGITIHFEDGTSHTASQVIWATGRRPNVKGLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGIYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFASMYSACTRNRQESRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMGATKADFDATVAIHPTASEEFVTMR"
     gene            44026..45225
                     /locus_tag="VXB91_000434"
     CDS             44026..45225
                     /locus_tag="VXB91_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HEV0469944.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTALKDE
                     PTHLVVAKEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVAKADRHINELNQARNEAASAPAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILVPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KADEATN"
     gene            45209..45910
                     /locus_tag="VXB91_000435"
     CDS             45209..45910
                     /locus_tag="VXB91_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0469945.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            45912..47171
                     /locus_tag="VXB91_000436"
     CDS             45912..47171
                     /locus_tag="VXB91_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0469946.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSSFTVSGKEEEIPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYGFGGLP
                     ITTNISLAANFNIDEIASIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESV
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            47295..49292
                     /gene="metG"
                     /locus_tag="VXB91_000437"
     CDS             47295..49292
                     /gene="metG"
                     /locus_tag="VXB91_000437"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEV0469947.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQAYVDGMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPDGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEQSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWVLAKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEIAYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFRLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIIAN
                     LKPRKMMKKYVSQGMILSAEHDGKLTLLTVDPAVPNGSVIG"
     gene            49336..49416
                     /locus_tag="VXB91_000438"
                     /pseudo
     CDS             49336..49416
                     /locus_tag="VXB91_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            49623..49943
                     /locus_tag="VXB91_000439"
     CDS             49623..49943
                     /locus_tag="VXB91_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEV0469948.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLMKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
     gene            49947..50762
                     /locus_tag="VXB91_000440"
     CDS             49947..50762
                     /locus_tag="VXB91_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0469949.1"
                     /translation="MKKMKYYEETSALLHEFSEENQKYFEELWESFNLAGFLYDEDYL
                     REQIYLMMLDFSEAERDGMSAEDYLGKNPKKIMKEILKGAPRSSIKESLLTPILVLAV
                     LRYYQLLSDFSKGPLLTVNLLTFLGQLLIFLIGFGLVATILRRSLVQDSPKMKIGTYI
                     VVGTIVLLVVLGYVGMASFIQEGVFYIPAPWDSLSVFTISLVIGIWNWKEAVFRPFVS
                     MIIAHLVVGSLLRYYEWMGISNVFLTKVIPLAVLFIGIFVLFRGFKKIKWSEV"
     gene            50837..51763
                     /locus_tag="VXB91_000441"
     CDS             50837..51763
                     /locus_tag="VXB91_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HEV0469950.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALMESDQVAEAFDLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCQLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSRAANFSLTRKEWYEIYLAAGNNLP"
     gene            51829..52095
                     /locus_tag="VXB91_000442"
     CDS             51829..52095
                     /locus_tag="VXB91_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HEV0469951.1"
                     /translation="MKNVELKEKNMTFEEILPGLKAKRKYVRTGWGGAENYVQLFDTI
                     EQNGLALEMTPYFLINVSGEGEGFSMWSPTVCDVLATDWVEVHD"
     gene            52088..52786
                     /locus_tag="VXB91_000443"
     CDS             52088..52786
                     /locus_tag="VXB91_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HEV0469952.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDF
                     HFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDAYKPLLEQTAQDIQEIFEINYIIPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEARI
                     QVFGIAPGAVKTAMTAADFETGGLADWVASETPIKRWIEPEEVAEVSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            52797..53276
                     /locus_tag="VXB91_000444"
     CDS             52797..53276
                     /locus_tag="VXB91_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV0469953.1"
                     /translation="MEIKNHFGVYCVCFENGKLLCIEKTRGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETGFTVRSYSNPRIYDVFVREELKNFMVHHVIALYDVEMNESAPQV
                     TISEAVSDGANDSLGYIWMDIQEITEENASPLVLKVKSELLGLPELDKTSYMNWKVK"
     gene            53284..54012
                     /locus_tag="VXB91_000445"
     CDS             53284..54012
                     /locus_tag="VXB91_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0469954.1"
                     /translation="MELFKTWKKNMVLYGLKSQIGTVYRNNDRTTSFYDVGNFLYLAG
                     ELDSRFWEDFVRKYGLDYKIIISENTNWQDFLHRKVGLNSFTRYSFKDKANFQVEFLN
                     NLVTHLEEGYNIVPIDNHIYNCFSTEEWSQDLQGDFESYQDFVLKGGFGFVILKNNEL
                     IAGISSGLVYRKAVEVEVATRPNEQGNGFAKKLGAAMILESLNRDMFPLWDAHNEASK
                     KVAEFLGYELSEPYEAFELEEILI"
     gene            54054..54923
                     /locus_tag="VXB91_000446"
     CDS             54054..54923
                     /locus_tag="VXB91_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-utilizing enzyme, TIM barrel domain protein"
                     /protein_id="HEV0469955.1"
                     /translation="MRNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRELNQNIILAS
                     CQQFVKDYLETICSLYSDEEVWYRFSELTNTEANCLVGTREFFDEGHPLFGYRGTRRL
                     LACLDEFQAEAHVVTEVYQTNPNLSLIFPFVNDADQLKQAITVLRQQGFTGKVGTMIE
                     LPSAYFDLSSILETGISKIVVGMNDLTSFVFATMRNSQWHDMESPIMLDMLRDMQDKA
                     RKNKIDFAVAGYLNTSFIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            54898..55338
                     /locus_tag="VXB91_000447"
     CDS             54898..55338
                     /locus_tag="VXB91_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HEV0469956.1"
                     /translation="MIPQEMWNKYKQINPLIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDIILDSQNQSVCIVEITKVSVELFNQVSAQHAFKEGE
                     GDKSLAYWRQVHEDFFTDCLGEVGLTFTPESKVVLEEFRKVYPL"
     gene            55461..58007
                     /locus_tag="VXB91_000448"
     CDS             55461..58007
                     /locus_tag="VXB91_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HEV0469957.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHISYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEARQVASQIFATHKENLAELPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
BASE COUNT        17965 a        10383 c        12558 g        17123 t
ORIGIN      
        1 ctaaaacatt gttagaaatc gatttgactg tcctgatcga tttgccctgt tcttgtttcg
       61 ttttactata gaacgatttg aaggcgttta tgatatttag ctgtacgaga gtctttaaaa
      121 agtgttttga tggtttggat ttcttcttta gttgatttca tatcactatt atataatgct
      181 ttttgatttt agtatagtat tatcgtagaa aatggactcg gtgctatgga tacaccggat
      241 gagaatggtt atgtagcaga tgactatcgg attacttact tagaggccca catcaaggcc
      301 atgcgagatg ccatttacaa agacggggtt gacttgcttg gttatacgac atggggctgt
      361 atcgattcgg tttcagctgg cacaggggaa atgaataagc gctatggttt tatctatgta
      421 gatcgagata atgtaggaaa tgggactctc aaacgtagca agaagaagtc cttctattgg
      481 tacatgtcat ttatagcaat ggtgtaagca tcgagtagag cacatttgtt tactattttt
      541 ataaaatctt ctccctgctt tataagatgt aaaaaagagt tcaattcgaa ctcttttttt
      601 gctataatga ggggagaaaa atcagacagg agattaagat gtcagaacca ttatttttac
      661 aatcagttat gcaagaaaaa atctggggtg gtaccaagct acgtgatgag tttggctacg
      721 acatcccaag tgaaaaagtc ggagagtact gggctatctc agctcatcta aatggtgttt
      781 ctaaagttgc caatggtcgt tacgagggaa cagatcttgc tactttgtat gcggaacacc
      841 gtgaattatt tggcaatcgt cctgagcctg tatttccgct tttgactaag attttggatg
      901 ctaacgactg gctcagcgtt caagttcacc cagacgatgc ttatggacta gagcatgaag
      961 gcgaacttgg aaaaacagaa tgctggtaca tcatcgctgc ggatgaaggt tcagagatta
     1021 tctacggcca caatgccaag tcaaaagaag aactccgcca gcaaatcgag gataagaact
     1081 gggatgcgct gttgacaaaa gtgccagtta aagcaggaga tttcttctat gtaccaagcg
     1141 gtaccatgca cgctatcggg gcgggtatct tgattcttga aacccagcag tctagcgata
     1201 ccacttaccg tgtctatgac tttgaccgta aggatgacaa gggcaattta cgtgaacttc
     1261 accttgaaaa atctatcgat gtcttgaaca ttggtgaacc cgcaaatagc cgtccagtga
     1321 caatcaaagc agatgatcta cgttccactc tccttgtatc caatgatttc ttcgcagttt
     1381 acaaatggga aattactgga aaagttaact ttgaaaagac agctgactac agcttgttga
     1441 gtgtcttggc tggtcaaggt caactaactg ttgacgggaa aaactatcca atccaaaaag
     1501 ggagacactt tatcctacca agtgatgttg aagcttggac tctggaaggg caagatttag
     1561 aattaattgt tagtcatcca taaaaaagaa agggcctgag ttcattactc aagtcctttt
     1621 tgattacata aattgggcga tgaagaccac gatgatgatt ggaatgacgg aacgaagaaa
     1681 cgaagaagga agagccagac ttggaacagt ccttgtttcc atgctctttc atcgagatgg
     1741 agttcctcca ttgcaagagc ctttttaaag atatagcctg taaaaagtga aaggtagaga
     1801 gctccaaatg gcatgaggag attgggaacc aagaagttca tagcgtcaaa gaaggtctta
     1861 ccaaaaatgt gaacatccgc catgacaccg taagataggg ctgaaggaat gccaaagaca
     1921 aaggtcaaaa ttcctaaaat aacactccat ttggcacgtt tgctgttatc ctggttggtg
     1981 atattgccca cattgatctc cagcatcacg acagaagaag tgacagtcgc aaagaggaag
     2041 aggacgtaga aaatggttcc aaaaggcatc ttgtcaaaga gttgaggcaa gacgataaag
     2101 agcaagctcg gtcccccttc agactggata ttgaaggggg accgagcttg gaaaatggct
     2161 agacctgcca tgatggatat cgagatattc atggctacga tggagattcc tgactggact
     2221 agattggttt tcttgtccaa gtaagaagca taggtcaaca tgactgtaac ccctagtgag
     2281 agggcaaaga aagattgtcc cagagcatag aggagaccag cgctagtcag ttttgaaaag
     2341 tctggtttga ggaagtaaag aaccccttcc atggcatttg gcaaactgag agagcgaccg
     2401 atgataacaa caaagatgat aaagagcagg ggcatcatga ctttcgaagc tctttcaatc
     2461 cctttttgaa ccccacgtga tacaataaag atatttaata agataaaggc tgcttgagct
     2521 cctagggcaa tggctggatt tgaaatgatt gaagtaaata actgagcata atcacccgtt
     2581 ccaccaagtt ggaacaattt cccaaactca atacctagat agactagaat ccatcctccg
     2641 ataacactgt aaaaagataa gaggataaag agggcaaagg cgccaatcca accgataaag
     2701 ttgtacttgt tattcttgcc cagttttcca aaggttttga tagcggaaac gccagcacta
     2761 cggccaaggg caaactcagc cagcaggaga gggaaaccga ttaaaatagt ggaaatgaga
     2821 aagattagta aaaagcctcc accgccatta gcagcagtca tgtagggaaa cttccaaacg
     2881 gaaccaagcc cgatgaccga gccagcagat gctagaataa agccaagttt cgacccccat
     2941 tgtgattttt ctgacatagt taaactctga tctccttttt caaaataaga aaaagctact
     3001 tgagttgtca aatagccttc tgtttgattg atagacttga ctatcctatt atgttttcta
     3061 aggtctgtca agaaaacaat tttcaagttt tcacaccttt ctcaaaaacg cttgactctg
     3121 acctaagggg aggggttata ctatcattgt aaggaggaaa tcatgtacca tataaaagaa
     3181 gctgcgcagc tttcaggtgt ctctgtcaag accctgccct gcatcactat gacaagatag
     3241 gactcttggt ccccttaaag tcggaaaacg gctatcgaac ctatagtcaa gaggatttgg
     3301 aacgccttca ggtcattctt tactacaaat atctaggctt ttctttagag aaaatagcag
     3361 aactgttaaa ggaagaaagg acagatttat tgctccattt gactaggtag ttggactatc
     3421 taactcgcga aaggcaacat ctggatacct tgatttccac cttgcaaaaa actattcaag
     3481 aacaaaaagg agaaagaaaa atgaccattg aggaaaaatt cacgggattt agctatcaag
     3541 acaatcaaaa ataccaccaa gaagcggtag agaaatatgg tcaagaagtc atgggacaag
     3601 cgctcgaacg ccaaaaaggt cacgaagacg aggctacggc cgcctttaac caagtctttc
     3661 aaactttggc acaaaatctt caagttggtt tacctgcaac agcaaccgaa aaccaggagc
     3721 aagcagccaa gctcttgcaa gccattcgca cttatggatt tgactgctct attgaggtat
     3781 tcggtcatat cggtaaaggt tacgtctaca acccagagtt taaggaaaac attgacaagt
     3841 ttggttctga aacagcccag tacacgtcag atgccattgc ggcttacgtt cagacaaatg
     3901 cagaaaaaat aggctaggaa tttcctagcc tattttttac ttcaaatcat aaagccagtc
     3961 gtcaccgttt ttgtagtaaa agaattcact gagatcttct tctagaaaca cacgaagcat
     4021 atcagacata tcatcggttg caagttttag atgagaaaga ttttcaaagt cctcccacca
     4081 aactttccct tcgtctgaag actggagttc accagtaaag tgttctgtct tgtaaaaaag
     4141 gacgacataa cgataatcct tgtcgtcata ccagtttttg ataccacaga gttggggttt
     4201 ggaaatgatc agaccagttt cttctttcac ttcacgaatg acagcatcga caaaggattc
     4261 gccacgttca acatgaccac caggaaaagt aatgccagac cagtcgggac taactcggtc
     4321 ttggaccagg accttatctc cgtttttaat catacacatg ttaacaaatt cgactgcctc
     4381 tcttctgttc attcttcaca acctttaatc tttaatcata atgcagactt cccgccaccc
     4441 agccggtaca gagggcagaa gtgatgttaa agccacccgt gtgggcattg atatccataa
     4501 cttcgcctgt aaagtggagg ccaggtacca gcttactttc aagggtttta ggattgattt
     4561 ccttgagact gactccaccc ttggtaacaa aggactttgc aagggacatt tttccagtta
     4621 caggaatttt aagttcttta atggactgga caagttgttc tcgttccttt tcagtcagtt
     4681 gtttgacttt ttcaggatat ccttgtacaa aaaattcggc caagcgttct ggtaacaagg
     4741 tttttaaagc gtttttcaag gatttttccc gattttcttc tagaaatgta accaagtcct
     4801 tctcagaaag ttgaggcaaa acatcgagtg agagaacctc cccacctttg acaaagctag
     4861 acatgcgtag ggcagcagga cctgacaaac caaagtgggt aaagagtaaa tcatgagtga
     4921 tgacatgctt accataactt agggtcacat cgtccagaga aatcccttgt aaggctttat
     4981 gtggaaaatc tgttaataaa ggactttcag cagcctcaag atcggtgatg gtatgcttaa
     5041 aatggcgagc aatctcgtga ccaaaaccag tcgaaccagt cgaaggataa gacttaccac
     5101 ctgttgtgac aatgagtttc tcacaagtga aggtttgatc cgctgactta aggacaaact
     5161 ggtcatctac ttttttaaca gaaacgattt ctatttgagt agcaacttga ccacctagtt
     5221 cggtgatttt cttttccaaa gcttcgataa tagtccgaga cttgtcactg gctggaaaga
     5281 cgcgtccgtg gtcttcgacc ttaagtttaa caccattttc tgtaaaaaag ttgatgatgt
     5341 catgattatc gaactgggag aaaacactgt aaagaaagcg tccgtttcca ggaattccag
     5401 ctagcaggtt gtctaagcta ccattgttgg tcacattgca acgtccccca ccagtcccag
     5461 ctaatttttt tccaagtttc cgattttttt cgatgaggag ggttttctgt ccataaaagc
     5521 tactggaaat cgtagccatc ataccagcag gtcccccacc gatgacaata gtatcaaaat
     5581 gtttcatagc tctattgtac cacaaaaaaa caagagatga tggtcacctc ttgtcaagaa
     5641 tgcaattaat caatttcata gcccatcagc aaaccgccct cttctgcata gaaactgcag
     5701 agaccagagg ttggtagaat tttaatatcc gcttgtggga aggtttcacg gattcgctct
     5761 gagagctgtt gacaacattt ttcgttattg cgttgggcca tgacaatacg gccaccagca
     5821 tatccagctt ttactaactc attataggca gcttgaactg atttctttga tccccttgct
     5881 ttttgtagca attcgagagt tccagtttca ctagcttttc cgaccatacg aatgttgaga
     5941 aggccaacga ccgtaccgat aagcttgctc aaacggccgt tcttcaccaa gttatcgact
     6001 ttggctagga caaagagcaa cttagttttt tcttgatagg cagtgatagc ttcaaccact
     6061 tcttcaaaag acaagccctg gtcaatcaag tcattcaatt tttctacgag taggtcaact
     6121 tcaccaccag cagataaact atcaatcaca tgaatcttag tgtcaggatg gtcttctaga
     6181 taaatattct ttgctagttg agcactattg tgactgccag aaagggtacc tgtgatggtt
     6241 actaggaaaa tgtttttggc accttcaaat gctcgcaaat agtcatctgg gcttggacaa
     6301 gccgattttg aagcttctgc agttgcatac atggtttcca tcatttggtc aatatcgaga
     6361 ctggcgtcat caacaaagac ctgatcagct acttgaatgg ttaaggggac acttacaaag
     6421 gttgtgttaa tagctggtgt tggcagttga cgataatcac aaccagagtc agcaataatt
     6481 ttccaagtca tagaaattct ccatctttgt cagttataca ttgacaaagg ttctgtcttt
     6541 ttttacaatt atatcatgaa aacccttgaa acaaaagcat catccgtctg ttgtgacaag
     6601 tagaaagaaa atgttatgtc tgaacgtaga atctctgaaa agtctcttga aaatctcaga
     6661 aaatcaaacc aagaatccaa tttattaacc agagaagcca ttgaaacagc cctcttgcaa
     6721 ctcttggaaa aaaaggagct gaccaagatt agtatttctg aattggtcaa acgtgcaggt
     6781 gtttcgcgtg cggcctttta tcgcaattat gactccaaag aggaaatttt agagagcgtc
     6841 tttaaacgaa ctgtccacaa tattatggaa cagctgcatc attacgattt aaagacagac
     6901 ctttatttgg tttgggttca ccttttccgg gaggccagaa aggaagctag agtgattcaa
     6961 ttggccttgg attaccatct ggaaaaaatc tttgtccaag ccatgcagga atttctagaa
     7021 aaataccatg ggaaatcaaa aggtgtcagc tcttatcttc attccttctg gagctcagcc
     7081 atcgtctctg tccttctaaa atggatcaag gatggcatga aggtaccagc tgaaaagatt
     7141 gcagatttag gtttaccatt ttttaaaaaa tagagaaaaa ggagaaaaga gatgactgaa
     7201 aaaagactgg cctgggatga gtattttgca gcccaagccc tactaattgc gaatcgttcc
     7261 acttgtaaac gtgctaaagt gggcgcgatt ctggtaaaag ataataaggt tatttccact
     7321 ggttacaatg gttcggtgtc agggactgag cattgtattg atcacgaatg tttggtcatt
     7381 gaaggccact gtgttcgcac ccttcacgct gaggtcaatg ctatccttca aggtgctgag
     7441 cgtggtgttc ccaaaggctt tacagcctat gtaacccatt ttccttgtct caactgtaca
     7501 aaacaattgc ttcaggtcgg ctgcaagcgc gtggtttata tcaaccagta ccgaatggac
     7561 gactacgccc aataccttta tcaagaaaaa gggacagaat tgacccattt accacttgag
     7621 acagtacaga cagctcttaa agaggctgat ctaatgtaaa aattatcaaa aataaatggc
     7681 ttagaaagat ttttaaaccg ttttttggta taataagaag aataaattga aagaaggaat
     7741 tccaaaaatg ggaaaaattg aagttattaa tcacccactg attcaacaca aattgtcaat
     7801 cttgcgtcgt acagatactt ctacaaaagc ttttcgtgag ctagtagatg agattgcaat
     7861 gttgatgggg tatgaagtac ttcgtgatct tccactagaa gatgtggaaa tcgaaacacc
     7921 aattacaaaa acagttcaaa aacaattggc aggtaagaaa ttggccatcg tcccaatctt
     7981 gcgtgcaggt atcgggatgg ttgatggtct cttgagcttg gttccagctg ctaaagttgg
     8041 ccacatcggt atgtaccgtg atgaagaaac acttcaacca gttgaatact tggtgaaatt
     8101 gcctgaggac attgaccaac gtcaaatttt tatagtagac ccaatgttgg caacaggtgg
     8161 ctcagcaatc ttggctgttg attctcttaa aaaacgtggc gcatcaaata tcaaatttgt
     8221 ctgccttgta tctgctccag agggtgtaaa agcccttcaa gaagctcatc cagatgtaga
     8281 aatctttaca gcagccttgg atgaacgttt gaacgaacac ggttatatcg ttccaggtct
     8341 tggagatgct ggagaccgct tgttcggtac aaaataagat cgaaaagaag aatgacttgg
     8401 aaaagtattt ccagtcacga aaggaggttg ggtttttgtt tctgtctaat gaaagcagag
     8461 caaaaatttg accttttttg accaagatat tataatagtc ttatcttcag tcatttgacc
     8521 aacaaaatta aaactcaaaa ggagaaatga atgattcctg tagttattga acaaacaagc
     8581 cgtggagaac gttcttacga tatttactca cgtcttctca aagaccgcat cattatgctg
     8641 acaggtccgg ttgaagacaa tatggctaac tctgttattg cccaattgct tttcttggat
     8701 gcccaagata gtacaaaaga tatttacctt tatgtcaata caccaggtgg ttctgtttca
     8761 gctggtttgg caatcgtaga taccatgaac tttatcaagg cagatgtcca aaccattgtt
     8821 atgggaatgg ctgcatctat gggaacagtc atcgcatcaa gtggagcaaa aggcaaacgt
     8881 ttcatgcttc caaatgctga atacatgatt caccaaccaa tgggcggtac aggtggtggt
     8941 acccaacaaa ctgatatggc tatcgctgca gaacacttgc tcaaaactcg taataccttg
     9001 gaaaaaatct tggctgaaaa ttcaggtcag tcaatggaaa aagtccatgc agatgcagaa
     9061 cgtgataact ggatgagcgc ccaggaaaca cttgaatatg gctttattga tgaaattatg
     9121 gccaacaatt cattgaacta atgatgatag aaggcaaact cgactgggtt tgcttttttt
     9181 ggtataatag ggagagattt cttagaaaga ggatttatca tgtttgaaaa agtcaatcgc
     9241 tctggcttga ttatctatct ttactataat cgtgatgcca aaaaactgca ggattatgga
     9301 gatattacct atcattccaa gaaacatcgt tacttacaac tctatgttcc aactcaagaa
     9361 gtggagcaat tggtcggacg cttgagcaag gaaaaattta ttaaaaaagt tagggtttgt
     9421 catatccaag agttggaaac accctttgtg ggcaatcttt atcgatagga aaacgttatc
     9481 atcgaaaaag ttcaaggaaa acattgacaa ttttctgata attcggtata ttcttaacag
     9541 actatttaag aaataaggag acaaaaagat gaagaaaaaa tttgccctat cgtttgtggc
     9601 gcttgcaagt gtagcacttc ttgcagcctg tggagaagtg aagtctggag cagtcaacac
     9661 tgctggtaac tcagtagagg aaaagacaat taaaatcggg tttaactttg aagaatcagg
     9721 ttctttagct gcatacggaa cagctgaaca aaaaggtgcc caattggctg ttgatgaaat
     9781 caatgccgca ggtggtatcg atggaaaaca aatcgaagta gtcgataaag ataataagtc
     9841 tgaaacagct gaggctgctt cagttacaac taaccttgta acccaatcta aagtatcagc
     9901 agtcgtagga cctgcaacat ctggtgcgac tgcagctgcg gtagcgaacg ctacaaaagc
     9961 aggtgttccc ttgatctcac caagtgcgac tcaagatgga ttgactaaag gtcaagatta
    10021 cctctttatt ggaactttcc aagatagctt ccaaggaaaa attatctcaa actatgtttc
    10081 tgaaaaatta aatgctaaga aagttgttct ttacactgac aatgccagtg actatgctaa
    10141 agggattgcc aaatctttcc gcgagtcata caagggtgaa atcgttgcag atgaaacttt
    10201 cgtagcaggt gacacagact tccaagcagc ccttacaaaa atgaaaggga aagactttga
    10261 tgctatcgtt gttcctggtt actataatga ggctggtaag attgtaaacc aagcgcgtgg
    10321 tatgggaatt gacaaaccaa tcgttggtgg tgatggattc aacggtgagg agtttgtaca
    10381 acaagcaact gctgaaaaag catcaaacat ctactttatc tcaggcttct caactactgt
    10441 agaagtttca gctaaagcta aagccttcct tgacgcttac cgtgctaagt acaatgaaga
    10501 gccttcaaca tttgcagcct tggcttatga ttcagttcac cttgtagcaa acgcagcaaa
    10561 aggtgctaaa aattcaggtg aaatcaagga taaccttgct aaaacaaaag attttgaagg
    10621 tgtaactggt caaacaagct tcgatgcaga ccacaacaca gtcaaaactg cttacatgat
    10681 gaccatgaac aatggtaaag ttgaagcagc agaagttgta aaaccataat agaaaaatgt
    10741 tgaaataggg aatgagcctt tgactcactc cctgtttcga tatttaatac tcttcgaaaa
    10801 tctcttcaaa ctgcgtcaac gtcgccttgg attatatatg tgactgactt cgtcagtctt
    10861 atctacaacc tcaaagcagt gctttgagca acctgcggct agtttcctag tttgctcttt
    10921 gattttcatt gagtataaga acctatcaaa aagtgaggga aacccctcgg aattataaat
    10981 agaaagagtg aatcttatgc tccaacaact cgtaaatggt ttgattctag gtagtgttta
    11041 cgcgctgtta gccctaggat ataccatggt ttacggaatt atcaagctca tcaacttcgc
    11101 ccatggtgat atttatatga tgggagcctt tatcggttat ttcttgatca attctttcca
    11161 aatgaatttc tttgtagcgc ttattgtagc tatgctagcg acagctattc ttggtgtcgt
    11221 gattgagttt cttgcttacc gacctttgcg ccactctact cgtattgctg ttttgattac
    11281 ggctattggg gtttctttcc tattggagta tggaatggtc tatctggttg gtgccaatac
    11341 ccgtgccttc cctcaagcga ttcaaacagt tcgatatgat ttgggaccaa ttagcttaac
    11401 aaatgtgcag ttaatgattt tggctatttc cttgattttg atgattttgt tacaagtcat
    11461 tgtccaaaag actaagatgg ggaaagccat gcgtgcagta tcagtagata gcgacgcggc
    11521 gcaattgatg gggatcaatg taaaccgtac gattagcttt accttcgctt tgggttctgc
    11581 tcttgcgggt gcggctggtg ttctgattgc tctttattat aactctcttg agcctttgat
    11641 gggggttact ccaggtctta aatctttcgt tgccgcagta cttggtggta tcggaattat
    11701 tcctggtgcg gctcttggtg gctttgtgat tggtctattg gaaacctttg cgactgcctt
    11761 tgggatgtca gatttccgtg atgccattgt ttatggaatc ttgttgttga tcttgattgt
    11821 ccgcccagct ggtatccttg gtaagaatgt gaaagagaag gtgtaaacga tgaaggaaaa
    11881 tttaaaagtt aatattctat ggttactcct tttgttagct ggctatagct tgattagtgt
    11941 actggtttca gtcggagtac ttaatctatt ctatgtacag attttacagc aaattggaat
    12001 taatattatt ttggctgttg gtctcaactt aatcgttggt ttttcaggac aattttcact
    12061 tggtcatgct ggtttcatgg cgattggtgc ctatgcagca gctattattg gttctaaatt
    12121 accaacctac ggtgccttct ttggagctat gcttgtaggg gctttgcttt caggagcagt
    12181 tgccttactt gtcggcattc caaccttgcg cttgaagggg gactatcttg cggtagcaac
    12241 tctgggtgtt tctgaaatta tccgtatctt tatcatcaat ggtggaagcc ttacaaatgg
    12301 tgcggcaggt atcttaggga ttcctaactt tacaacttgg caaatggttt acttctttgt
    12361 cgtgattaca accattgcaa ccttgaactt cttgcgtagc ccaattggtc gttcaaccct
    12421 ctctgttcgt gaagatgaaa tcgctgctga gtcagttggg gttaatacga ctaaaattaa
    12481 aatcatcgct tttgtctttg gtgccattac tgcaagtatt gctgggtcac ttcaggcagg
    12541 atttatcggg tctgttgtac cgaaagatta caccttcatc aactcaatca acgttttgat
    12601 tattgttgta tttggtggac tcggttccat tacaggtgcg attgtttcgg ctattgttct
    12661 gggaattttg aatatgcttc tccaagatgt tgctagtgtg cgtatgatta tttacgcttt
    12721 ggccttggta ttggtaatga ttttcagacc aggtggactc cttggaacat gggaactgag
    12781 cctatcacgt ttctttaaaa aatctaagaa ggaggaacaa aactaatggc attacttgaa
    12841 gtaaaacagt taaccaaaca ttttggtggt ctaacagctg ttggagatgt gactcttgaa
    12901 ttgaacgaag gggaactggt tggattaatc ggtccaaacg gagctgggaa aaccaccctt
    12961 ttcaaccttt tgaccggtgt ttatgaacca agcgagggaa cagtaaccct agatggtcac
    13021 cttttgaatg ggaaatcacc ttataagatt gcctctttgg gacttggacg tactttccaa
    13081 aatatccgtc tctttaaaga tttaacagtt ttagacaatg ttttgattgc ttttggaaac
    13141 catcacaaac aacatgtttt tactagtttc ttacgcttac cagcttttta caagagtgaa
    13201 aaagaattaa aggctaaagc tttggaattg ttgaaaatct ttgatttaga tggtgatgca
    13261 gagactcttg ctaaaaatct ttcctacgga caacaacgtc gtttggaaat tgttcgtgcc
    13321 cttgctacgg aacctaaaat tctcttctta gatgaaccag cagcaggtat gaacccacag
    13381 gaaacagccg aattgactga gttaattcgt cgtatcaaag atgaatttaa gattacaatc
    13441 atgttgattg aacacgatat gaatctggtc atggaagtaa cagaacgtat ctacgtactt
    13501 gaatatggcc gtttaattgc tcaaggaact ccagacgaaa ttaagaccaa taaacgcgtt
    13561 atcgaagctt atctaggagg tgaagcctaa tgtctatgtt aaaagttgaa aatctttctg
    13621 tgcattacgg tatgatccaa gcagtccgtg atgtaagctt tgaagttaat gaaggagaag
    13681 ttgtttccct tatcggtgcc aacggtgcag gtaagacaac tattcttcgc accttgtcag
    13741 gtttggttcg accaagttca ggaaagattg aatttttagg tcaagaaatc caaaaaatgc
    13801 cagctcagaa aattgtggca ggtggtcttt cacaagttcc agaaggacgc cacgtctttc
    13861 ctggcttgac tgttatggaa aatcttgaaa tgggagcttt cttaaagaaa aatcgtgaag
    13921 aaaatcaagc taacttgaag aaggttttct cacgctttcc tcgtcttgaa gaacgtaaga
    13981 accaagatgc agctactctt tcaggagggg aacaacaaat gcttgccatg ggacgcgctc
    14041 ttatgtcaac accaaaactt cttcttttag atgaaccatc aatgggactt gccccaatct
    14101 tcatccaaga gatttttgat atcattcaag atattcagaa gcaaggaaca accgtcctct
    14161 tgattgaaca aaatgccaat aaagcacttg caatctctga ccgaggatat gtactggaaa
    14221 cagggaaaat cgtcctatca ggaacaggaa aagaactcgc ctcatcagaa gaagtcagaa
    14281 aagcatatct aggtggctaa aacaatccag tggattgttt tagtcggcag atgaagatta
    14341 cgaagtaatc atcattatag tctgggagac tagtttaggt tgcagataaa gattgcgaag
    14401 caatcatcaa atccagtgga ttgttttagt cggcagatgg agattacgaa gtaatcatca
    14461 atatagtccg ggggaccttt ttagtcggta gattgagatt gcaaacaaat ctgcatctac
    14521 attgaaagct taatttctaa taattgaaaa aatcgaatga aaaatttctt accttcattc
    14581 acagagctcg atttcagagc tctttttgct agcttattca tacttttctg aatttcgaaa
    14641 aagaaatgta agcgtttgat agatttacaa aaagattgta taatagggat aagaatagaa
    14701 aaggagaagt ctcatggcag ttaaagattt tatgacccgc aaggtagttt atattagtcc
    14761 agatacaaca gtatctcatg cagcagattt gatgagagag caaggtttgc accgtctgcc
    14821 tgttatcgaa aatgatcaat tagttggttt ggtgactgag ggaaccattg cacaagcaag
    14881 tccatctaaa gcaacaagtc tttctatcta tgagatgaat tatcttctga ataagacaaa
    14941 agtaaaagat gtcatgattc gcgatgttgt cactgtctca ggctatgcta gtctagaaga
    15001 tgcaacttat ctgatgttga aaaataagat tagtattctc cctgtcgtag ataaccatca
    15061 agtatacgga gttattactg accgtgacgt tttccaagcc tttcttgaaa ttgcaggtta
    15121 tggcgaagaa gggattcgtg tacgctttgt tacagaagat gaagttggtg ttcttggaaa
    15181 aattgtttct ttgattgtag aagaaaattt gaatatctcc catacagtca atattccgcg
    15241 taaggatggt aaggtgatta tcgaagtgca aatcgatgga tcaattgatt taccagcctt
    15301 gaaagaaaaa tttgaagcaa atggtattca agtggaagaa atcgctcgca cttcagcaaa
    15361 agtcttgtaa gaagggaagc ccaaaggctt cttttttcat gaaaagggga ttagagaaaa
    15421 agatggaaag aaatgataaa atatgctata atgaaataat gtaaaaaagg agtatttatg
    15481 gacatttcag taattcgtca gaaaattgac gcaaatcgtg aaaaattagc ttctttcagg
    15541 gggtctcttt gacctcgaag ggctagagga ggagattgcc atcttggaaa acaagatgac
    15601 agaacctgat ttttggaacg ataatattgc agcccaaaaa acgtcgcaag aattaaatga
    15661 attaaaaaac acttacaata ccttccataa gatggaagag ttgcaggatg aagtcgaaat
    15721 tttattggat tttttggctg aagacgagtc agtgcatgat gaactggtag cgcagttagc
    15781 cgaacttgat aagataatga ccagctacga gatgactcta ctcttgtcag aaccttatga
    15841 ccacaacaat gccatcttgg aaatccatcc aggttctggt ggtactgagg cgcaggactg
    15901 gggtgatatg ttgcttcgta tgtatactcg ttatggtaat gctaaaggct ttaaagtgga
    15961 agtgttggat taccaagcag gtgatgaggc tggtattaag tcggtaactt tatcatttga
    16021 agggcctaat gcctatggtc tcctcaagtc agaaatgggt gttcaccgct tagtgcgaat
    16081 ctcaccattt gactctgcca aacgtcgcca tacctctttc acatctgtag aagtgatgcc
    16141 agaattggat gatactattg aagtggaaat ccgtgaagat gatatcaaga tggatacctt
    16201 ccgttcaggt ggtgccggtg gacaaaacgt caataaggtt tcaacaggtg tacgtttaac
    16261 ccacattcca actggaattg ttgtccaatc aacagtggat cgtacccagt atggaaatag
    16321 agatcgtgcc atgaagatgt tgcaggctaa gctctatcaa atggagcaag agaagaaggc
    16381 tgcagaggta gattctctca aaggtgagaa aaaggagatc acttggggaa gccaaatccg
    16441 ttcttatgtc ttcacgcctt atactatggt aaaagatcac cgaactagct ttgaggttgc
    16501 tcaggtagat aaggttatgg atggggactt agatggtttt atcgatgctt atctcaagtg
    16561 gcgaattagc taagatagaa aggaactcac atgtcaatta ttgaaatgag agatgtcgtt
    16621 aaaaaatacg acaacggaac gactgctcta cgcggtgttt cggttagcgt tcaaccgggg
    16681 gaatttgctt acatcgtagg accttcagga gcagggaagt caacttttat tcgttctctg
    16741 tatcgtgaag taaaaatcga taaaggaagc ctatcagttg ctggttttaa tctggttaag
    16801 atcaaaaaga aagatatccc gcttctacgt cgtagtgttg gggttgtctt ccaggattat
    16861 aaattgttac caaagaaaac tgtctatgaa aatattgctt acgctatgga agtaatcggg
    16921 gaaaatcgcc gtaatatcaa aagacgagtg atggaagttt tggacttggt tggattgaag
    16981 cataaggttc gttctttccc aaatgaactc tcaggtgggg agcaacagcg gattgcgatt
    17041 gcgcgtgcaa ttgtaaataa tcccaaagta ttgatagctg atgagccaac aggaaatctg
    17101 gatccggata attcatggga aattatgaat cttttggaac ggattaacct acaaggaaca
    17161 actattttga tggcgactca taatagccag attgtaaata ccttgcgcca ccgtgtcatt
    17221 gccattgaaa atggccgtgt cgttcgtgac gaatcaaaag gagagtatgg atacgatgat
    17281 tagtagattt tttcgccatt tatttgaagc cttaaaaagt ttgaaacgaa atggttggat
    17341 gacagtagct gctgtcagtt cagtcatgat tactttgacc ttggtggcaa tatttgcatc
    17401 tgttattttc aatacagcga aactagctac agatattgaa aataatgtcc gtgtagtagt
    17461 ttatatccga aaggatgtgg aagataatag tcagacaatt gaaaaagaag gtcaaactgt
    17521 tacaaataat gactaccaca aggtatatga ttctttgaag aacatgtcta cggttaaaag
    17581 tgttaccttt tcaagtaaag aagaacaata tgaaaaatta accgagataa tgggagataa
    17641 ctggaaaatc tttgaaggag atgccaatcc tctctatgat gcctatattg tagaggcaaa
    17701 cactccaaat gatgtaaaaa ctatagccga agatgctaaa aaaattgaag gtgtctctga
    17761 ggttcaagat ggcggtgcca atacagaaag actcttcaag ttagcttcat ttatccgtgt
    17821 ttggggacta gggattgctg ctttgttaat ttttatcgca gttttcttga tttcaaatac
    17881 cattcgtatt accattattt cccgcagtcg cgaaattcaa atcatgcgct tggtcggagc
    17941 taaaaacagt tatatccgtg gaccgttctt gttagaagga gcctttatcg gtttattggg
    18001 agctatcgca ccatctgttt tggtctttat tgtttatcaa attgtttacc aatctgtcaa
    18061 caaatcgttg gtagggcaaa atctatccat gattagtcca gatttattta gtccgttgat
    18121 gattgcccta ctatttgtga ttggggtttt cattggttca ttgggatcag gaatatccat
    18181 gcgccgattc ttgaaggttt aggtaaaata gctgctttta tgaggagatt gtaaaatctc
    18241 cttttttgct acaagagttt ttgaaaagag atgcgcagaa gaaaagagct tccaaagaag
    18301 tcccccagag aagacttctt gatggctaat ttgaacttga aatttggcgc actagaaatt
    18361 ttttagaaaa aagtgtaatt tttttataaa agcctttaca aaaaaaatta aagtggtata
    18421 attaaattat agaaagtgca aacgttttcg taaaacgttt gcctaaataa aaataaagga
    18481 gatttgaatg atgaaagata cattcaaaaa tgtcttgtct ttcgaatttt ggcaaaaatt
    18541 cggtaaggct ttgatggtag ttatcgcggt tatgccggct gctggtttga tgatttcaat
    18601 cggtaagtct atcgtgatga ttaacccaac ctttgcacca cttgtcatca caggtggaat
    18661 tcttgagcaa atcggttggg gggttatcgg taaccttcac attttgtttg ccctagccat
    18721 tggaggaagc tgggctaaag aacgtgctgg tggtgctttc gccgctggtc ttgccttcat
    18781 cttgattaac cgtatcactg gtacaatctt tggtgtatca ggcgatatgt tgaaaaatcc
    18841 agatgctatg gtaactactt tctttggtgg ttcaatcaaa gttgctgatt actttatcag
    18901 tgttcttgaa gctccagcct tgaacatggg ggtattcgta gggattatct caggttttgt
    18961 aggggcaact gcttacaaca aatactacaa cttccgtaaa cttcctgatg cactttcatt
    19021 cttcaacggg aaacgtttcg taccatttgt agttattctt cgttcagcaa tcgctgcaat
    19081 tctacttgct gctttctggc cagtagttca aacaggtatc aataacttcg gtatctggat
    19141 tgccaactca caagaaactg ctccaattct tgcaccattc ttgtatggta ctttggaacg
    19201 tttgctcttg ccatttggtc ttcaccacat gttgactatc ccaatgaact acacagctct
    19261 tggtggtact tatgacattt taactggtgc agctaaaggt actcaagtat tcggtcaaga
    19321 cccactatgg cttgcatggg taacagacct tgtaaacctt aaaggtactg atgctagtca
    19381 atatcaacac ttgttagata cagtacatcc agctcgtttc aaagttggac aaatgatcgg
    19441 ttcattcggt atcttgatgg gtgtgattgt tgctatctac cgtaatgttg atgctgacaa
    19501 gaaacataaa tacaaaggta tgatgattgc aacagctctt gcaacattct tgacaggggt
    19561 tactgaacca atcgaataca tgttcatgtt catcgcaaca cctatgtatc ttgtttactc
    19621 acttgttcaa ggtgctgcct tcgctatggc tgacgtcgta aacctacgta tgcactcatt
    19681 cggttcaatc gagttcttga ctcgtacacc tattgcaatc agtgctggta ttggtatgga
    19741 tatcgttaac ttcgtttggg taactgttct ctttgctgta atcatgtact ttatcgcaaa
    19801 cttcatgatt caaaaattca actacgcaac tccagggcgc aacggaaact acgaaactgc
    19861 tgaaggttca gaagaaacca gcagcgaagt gaaagttgca gcaggctctc aagctgtaaa
    19921 cattatcaac cttcttggtg gacgtgtaaa catcgttgat gttgatgcat gtatgactcg
    19981 tcttcgtgta actgttaaag atgcagataa agtaggaaat gcagagcaat ggaaagcaga
    20041 aggagctatg ggtcttgtga tgaaaggaca aggggttcaa gctatctacg gtccaaaagc
    20101 tgacattttg aaatctgata tccaagatat ccttgattca ggtgaaatca ttcctgaaac
    20161 tcttccaagc caaatgactg aagcacaaca aaacactgtt cacttcaaag atcttactga
    20221 ggaagtttac tcagtagcag acggtcaagt tgttgctttg gaacaagtaa aggatccagt
    20281 atttgctcaa aaaatgatgg gtgatggatt tgcagtagaa cctgcaaatg gaaacattgt
    20341 atctccagtt tcaggtactg tgtcaagcat cttcccaaca aaacatgctt ttggtattgt
    20401 gacggaagca ggtcttgaag tattggttca cattggtttg gacacagtaa gtcttgaagg
    20461 taaaccattt acagttcatg ttgctgaagg acaaaaagtt gcagcaggag atctccttgt
    20521 cacagctgac ttggatgcta tccgtgcagc aggacgtgaa acttcaacag tagttgtctt
    20581 cacaaatggt gatgcaatta aatcagttaa attagaaaaa acaggttctc ttgcagctaa
    20641 aacagcagtt gctaaagtag aattgtaata tacttgaggt tggaagctgt attccaacct
    20701 cttattttgg gagaaaagaa tgaaattttt aacactcaat actcacagtt ggatggagaa
    20761 agaagcagag gaaaaattcc agattttgct tgaagatatt cttgaaaagg actatgattt
    20821 gatttgtttc caagaaatca atcaggagat gacctcgtca gaggtggagg ttaatgacct
    20881 ttatcaagct ttgccagcag ctgagcctat tcaccaagac cattatgtta gactcttggt
    20941 tgaaaagttg ttagagcaag ggaaaaatta ctactggacc tgggcttata accatatcgg
    21001 ctatgaccgc taccacgaag gtgtggctat cttgtctaaa acacctattg aagccagaga
    21061 aattttggtt tcagatgtgg atgatccaac agactatcat actcgccgtg ttgccctagc
    21121 tgaaactgta gtcgatggca aggagctagc agttgccagt gttcatctct cttggtggga
    21181 taaaggtttc caagaagaat gggcacgatt tgaggctgtc ttgaaaaaat tgaacaagcc
    21241 acttttacta gctggagatt ttaacaaccc agcaggtcag gaaggttacc aagctatttt
    21301 agctagtcca ttaggcttac aagacgcatt tgaagttgct caagagaaaa gtggtagcta
    21361 tactgttccg cctgaaattg atggctggaa agggaacact gaaccccttc gaatcgatta
    21421 tgtctttact accaaagagt tagcggtgga aaatttacat gtcgtatttg atggtaacaa
    21481 gagtccacaa gtgagtgatc actatggctt gaatgctata ttaaactgga aataataact
    21541 gaaaagaggt tggaactata aaattccagc cttttcttac tagagaagct actggaaata
    21601 gcctaaataa gtgagactac tgtaatggaa taaaatatgg tataattgat aaggtagata
    21661 gaatcgagga tgttatgtca tttacgaaat ttcaatttaa aaactatatt agagaagcct
    21721 tgaaggagtt aaaatttaca actccaacag aggtgcaaga caagttgatt cctattgttt
    21781 tggcaggtcg tgacctagta ggagaatcaa aaacaggttc aggtaagact catactttct
    21841 tgttaccgat tttccagcaa ttagatgaag ctagcgatag tgtacaagca gtgattactg
    21901 caccgagtcg tgagttggct actcaaattt accaagtagc gcgtcagatt tcagctcact
    21961 cagatgtcga agttcgtgtg gttaattatg tgggtggtac ggataaggct cgccagattg
    22021 agaaattggc aagcaatcag cctcatattg ttattggaac accaggccgt atctacgact
    22081 tggttaaatc tggtgattta gctattcata aagccaagac atttgttgtt gatgaagcag
    22141 atatgacctt ggatatggga ttcttggaaa ctgttgataa gattgctggc agtcttccaa
    22201 aagacttgca attcatggtc ttctcagcga ctatcccaca aaaactgcaa ccattcttga
    22261 aaaaatactt atcaaatcct gttatggaga aaattaagac caaaacggtt atttctgaca
    22321 ccattgataa ttggttgatt tcgaccaagg gacatgataa gaatgctcaa atttaccagt
    22381 tgactcagtt gatgcagccg tatttggcaa tgatttttgt taacactaaa acacgtgctg
    22441 atgaattgca ttcatatctg actgctcaag gcttgaaggt tgcaaaaatc catggagata
    22501 ttgcccctcg tgaacgcaag cgaatcatga atcaggtgca aaatctggat tttgagtata
    22561 ttgtcgcaac agatttggca gcgcgtggga ttgacattga aggtgtcagc catgtcatca
    22621 atgatgccat tccgcaagac ttatcttttt ttgttcatcg tgttggtcgt actggacgaa
    22681 atggcctacc aggtacagct attacccttt atcagccaag tgatgactcg gatatccgtg
    22741 agttggagaa attgggaatc aagtttagtc ctaagatggt caaagacggg gaatttcaag
    22801 atacctatga ccgtgatcgt cgtgccaacc gtgagaaaaa acaagataaa cttgatatcg
    22861 aaatgattgg tttggttaaa aagaaaaaga aaaaagtcaa accgggttat aagaagaaaa
    22921 ttcaatgggc ggttgatgaa aagcgccgta aaaccaagcg tgctgaaaat cgcgctcgcg
    22981 gtcgtgcaga gcgtaaagct aaacgccaaa cattttaata gaaattgttg gagtattgag
    23041 ctccaacttt tttatttatg agaacgaact atctaaaccg aaacactaca ttaaagactg
    23101 caaattgcga ttaaaaatgg tataatgata aagttatata gtcccgataa gatggtaggt
    23161 atttattacg aagagttttc ctatcagtac tttgtaactc tataacaata ttttttaagg
    23221 gggggacatt tttatgtcag agcgtaaatt attcacgtct gaatctgtat ctgaggggca
    23281 tccggataag attgcagacc aaatttcaga tgcgattttg gatgctattt tagcaaagga
    23341 tccagaggcg cacgttgctg ctgaaacagc tgtatatact ggttctgtcc acgtttttgg
    23401 tgaaatttct acaaatgcct atgtggatat taaccgtgtg gttcgtgata ccattgcaga
    23461 gattggttat accaatacag aatatggatt ttctgctgag acggtgggag tacacccatc
    23521 tttggtggaa caatctcctg acatcgctca aggtgttaac gaagccttgg aggttcgtgg
    23581 aaatgctgat caagatccac tggacttgat tggagcaggt gaccaagggc tcatgtttgg
    23641 atttgcagta gatgaaacag aagagctcat gccattgcca attgcactca gtcataaatt
    23701 ggttcgtcgt ctggcagaac ttcgtaagtc tgaagaaatt agctatctcc gtccagatgc
    23761 aaaatcacaa gttacagttg agtacgatga aaatgaccgt ccggtacgtg tagatacagt
    23821 cgttatttct actcagcatg atccagaggc cactaatgaa caaatccatc aagatgtgat
    23881 taaaaaggtc atcaaagaag ttattccatc ttcttatctt gatgataaga caaaattctt
    23941 tatcaatccg acaggtcgtt ttgtaatcgg tggtcctcaa ggggactcag gtttgactgg
    24001 tcgtaagatt attgtagata cttatggtgg ctactctcgt catggtggtg gtgccttctc
    24061 tggtaaagat gcgactaagg tggatcgttc agcctcttat gcggctcgct atattgccaa
    24121 gaatatcgtt gcagcagacc ttgctaagaa ggcagaagtg cagttggcct atgctatcgg
    24181 tgttgcgcaa cctgtttctg ttcgtatcga tactttcggt acaggaacag tagctgaaag
    24241 tcaacttgaa aaagcggctc gtcaaatctt tgaccttcgc cctgcaggga ttatccaaat
    24301 gctggacctc aagcgtccaa tttaccgtca aacatcggct tacggtcaca tgggacgtac
    24361 agatattgat cttccatggg aacgtttgga taaggtagat gctttgaaag aagcagtaaa
    24421 ataagatttt aagaggggaa cgtcctctct tttttatagt ttttaactat actgggatac
    24481 tgttctgaaa atccattttg tgaaagtaga gatttacatg tatagtagat tgaaactaga
    24541 atagtacacc tcaacttcta aaacattgtt agaaatcgat ttgactgtcc tgattgattt
    24601 ctcctgttct tgtttcattt tactatattt ctttaaaaat gataaaggtt gagatttctc
    24661 ctcgtaatag ataatcatgg ggatatttca atccaaagtt ttattcgtta tcacttgact
    24721 attgcaaggt tttctagagc aacagagtca tggaatggac tcatggttga gatttctcct
    24781 tgttgcttgg acttcattca aaagtctgtt acccaagcct tgttcaaact tccaatacac
    24841 tagctgtttc catagcatga cttctgtact agactttctt ttccgaataa atagatagaa
    24901 ccacagaatc tagtaaacct agaattaaaa ttatggtata atattagcaa taaaagaaat
    24961 ctggaggatt agaatcatgg tatcaacgaa aacacaaatt gctggttttg agtttgacaa
    25021 ttgcttgatg aatgcagcag gtgtggcttg tatgacgata gaggagttag aagaggtcaa
    25081 aaactcagcg gcaggaacct ttgttactaa gacagcgacc ttggacttcc gtcaggggaa
    25141 tcctgagcca cgctaccaag atgttccact tggttccatc aactctatgg gcttgccaaa
    25201 taatggctta gactattatt tggattatct tttagatttg caggaaaaag agtcgaaccg
    25261 aactttcttc ttatctctgg tcggcatgtc tccagaggaa acccatacta ttttgaaaaa
    25321 agtccaagag agtgattttc gtggtctgac tgagctaaat ctttcctgtc caaatgttcc
    25381 aggtaaacct cagattgcct atgattttga gacaacagac cggattttgg cagaagtgtt
    25441 tgcttacttc accaaacctc ttggaattaa attgccacct tattttgata ttgttcactt
    25501 tgatcaagcg gcagctattt tcaacaaata tccgctcaag tttgtcaact gcgttaactc
    25561 tatcggaaac ggcctctata tagaagacga atctgtcgtt attcggccta agaatggttt
    25621 tggtggaatt ggtggagaat acatcaaacc gactgctcta gccaatgttc acgcctttta
    25681 tcaacgttta aatcctcaaa tccaaattat cggaacaggt ggcgttctga ctggtcgaga
    25741 tgcctttgaa cacatcctct gtggagcaag tatggtgcag gtgggaacga cccttcacaa
    25801 agaaggtgtc agtgcttttg accgcattac caatgaactg aaagcaatca tggtggaaaa
    25861 aggctacgag agcttagaag atttccgtgg gaaattgcgc tatattgact aaattaaatc
    25921 gaaaaatctg aagaaaggag agacgatgct agccattgaa gaaagtcaga agttgacttt
    25981 atcaaattta ccgagcctga gcctatttac agggacagat cagggtcagt ttgaagtgat
    26041 gaagagtcaa gtgttgaaac agattgggta tgattctgct gacctcaact ttgcctactt
    26101 tgatatgaaa gaagtagttt acaaggatgt ggaactggag ttggtcagcc ttcctttctt
    26161 tgcggatgag aaaatcgtga tattagatta ttttatggat atcacgactg ctaagaaacg
    26221 ctttttgaca gatgatgagc ttaagtcatt tgaggaatac cttgacaatc cttctccaac
    26281 aaccaagttg ataatctttg cagaaggaaa gctggatagc aaaagacggt tagtcaaatt
    26341 acttaagcgt gatgccaagg tcttcgatgc agtagaagta aaagaacaag aattgcgcca
    26401 gtatttccaa aagtggagtc agaaacaagg tctgcagttt accaatcatt cttttgaaaa
    26461 tctcctcatc aagtcggggt ttcaatttag cgaaatccag aaaaatcttc tctttttaca
    26521 gtcctataag gcgaattctg ttatcgagga agaggatatt gttaacgcaa ttcccaagac
    26581 cttgcaggac aatatttttg atttaactca gtttattctg actaaaaaga tggatcaggc
    26641 gcgcgatttg gtgagagact tgaccttgca aggggaagat gaaatcaaac tgattgcagt
    26701 catgctggga caatttcgga cttttactca ggtgaagatt ttggcggagt ctggccaaac
    26761 agaatcgcag attgcaagta gtttaggtag ttatctggga cgtaacccaa atccttatca
    26821 aatcaagttt gcattaagag attcgagagg actttctttg agctttctga agcaagctat
    26881 ttcctatttg attgagacag actatcagat taagacaggt ctttatgaaa aaggtttcct
    26941 ttttgaaaag gcactcttac agattgctag tcaggtcaat tgacatttgt tgaaactaca
    27001 acccacgtca ggattatctt gtcgtgggtt tcttgctgat ttgcttattt tattagaaag
    27061 tatgtcagtg atttccttat ctataagcaa aaaacttgaa aaaagtgaat gtttgcgtta
    27121 tcattttcat atagaaagaa aaagaggtat tacagatggc tattatctta ccagaacttc
    27181 catatgcata cgacgctttg gaaccataca tcgatgcgga aacaatgcat ttgcaccatg
    27241 acaaacacca tcaaacttat gtcaacaatg ccaatgcagc tttagaaaaa caccctgaaa
    27301 tcggtgaaga ccttgaagcc ttgcttgctg atgtagaatc tatcccagct gatatccgtc
    27361 aagcacttat caacaatggt ggcggacact tgaaccacgc tcttttctgg gaattgatga
    27421 ctcccgagaa aacagctcct tcagcagaac tgacagcagc aatcgatgca acatttggtt
    27481 catttgaaga attccaagca gccttcactg cagcagcaac aactcgtttt ggttcaggtt
    27541 gggcatggtt ggttgtcaac aaagaaggga aacttgaagt gacttcaaca gcaaaccaag
    27601 acacaccaat ctcagaaggt aaaaaaccaa tcttgggctt ggacgtttgg gaacatgctt
    27661 actacgtgaa ataccgcaac gtgcgtcctg actatatcaa agctttcttt tcagtaatca
    27721 actggaataa agtagatgaa ttgtacgcag ctgctaaata atgatagttg gagggaagaa
    27781 ttgttcttct cttttttagg ttataagatt ctggtctgac aaaatcgtca gacttttttc
    27841 atttttatga gaaacgtgct aactgctaga aattatggta gaataaagta ttaagtaatc
    27901 gtggaaaaag gatatctatg cgaaaagaaa ttgcacctga attatacaac tataacaagt
    27961 ttcctggtcc ggagttccat ttacacgggg acaaggtcga aacggaaggg atagcttttt
    28021 ccttggttga aaatatcaag gatgcctttg atgtgacgac ttttaatcag cgtttttcag
    28081 aagtattaac caagtttgat tatatcgtgg gggactggag caacgaacag cttcgcctac
    28141 gaggttttta caaggatgac cgaacagaag aaaaacttga aaaaatcagt cgtttacaag
    28201 actacctttt agagtattgt agttatggtt gtgcctattt tgtcttagaa aatgaagccc
    28261 ctaagcgagt atcatttgac aagaaaatgc gtaagacgga agaagaaaca ccttctagaa
    28321 aaggaaagaa accgactcaa actaaacgaa agtcgaatgc agataagaaa aatagacgtc
    28381 gtcagaaaga ccaacattct cagaaagagg acaaggaaca acgtcatttt gtcattcgtc
    28441 agaagtgagt agagaataag gagaagaaat gaaaccctca attcatagtt tggcacatca
    28501 aaccatgcag gaatgggtat tggagcaggg agaaaagaaa ttccgtgcag atcaaatctg
    28561 ggaatggctc taccgtaaac gtgtgcagtc atttgaagaa atgaccaacc tttccaagga
    28621 tttgattgct aagctcaatg accagtttgt ggtcaatccc ttgaaacaac gtattgtgca
    28681 agagtctgct gatggtacag tcaaatatct ctttgaattg cccgacggta tgttaattga
    28741 gactgtactc atgcgtcaac actatggttt atctgtctgt gtgaccactc aggtcagctg
    28801 taatatcggt tgtaccttct gtgcctctgg tttgattaag aagcagcgtg acctcaataa
    28861 cggtgaaatc gtagcgcaaa tcatgctggt tcagaaatac tttgctgatg aaggggttca
    28921 ggtcaatctt gccgtgtctc ttcacgcacc caacaatgaa cttcgttcaa gtatcatgaa
    28981 aattaaccgt gcctttccga ttgaaaaact ctttgctgct attgaatact acattgagac
    29041 aacaaaccgt cgtgtaacct ttgaatatat catgcttaat gaagtcaacg acggtgtaga
    29101 acaagccttg gaattggctg aattgctcaa gaacatcaag aaattgtctt atgtaaactt
    29161 gattccttat aacccagtta gtgagcatga ccaatatagc cgtagtccca aagagcgcgt
    29221 gttggctttc tatgatacgc ttaagaaaaa agggggcaac tgtgtggttc gtcaagagca
    29281 tggtacagat attgacgcag cttgtggaca attgcgcttt aacacaatga aacgtgaccg
    29341 ccagaaggca gtcgcagcgg taaatcctta atgatgaaga agacttataa tcatattttg
    29401 gtctggggag tcattttcta tagcatttgc attgtctatt tttgctttac tcctcaagaa
    29461 caatctaccg tgggagtggg aactccagat attcagcctc ttggacgcct ggtttttctt
    29521 ttgactcctt tcaattctct ctggaaactg ggcgaagtga gtgacattgg acaattatgt
    29581 tggatttttt tacaaaatat cctcaatgtc ttcttgtttt ttcctctgat tttccaactc
    29641 ctttatctat ttccaaattt gcggaaaaca aaaaaggtcc ttctttttag ttttcttgtg
    29701 agtcttggaa tcgagtgtac gcaattaatc ttggactttt tctttgattt taatcgcgtc
    29761 tttgagattg atgatttgtg gaccaacact ttgggtggct atctggcttg gctcctttat
    29821 aaacgattac ataaaaacaa gataaggaat taaaatgagt attttagaag ttaaaaatct
    29881 gagtcacggt tttggtgacc gtgcaatttt tgaagatgtg tccttccgtc tcctcaaggg
    29941 agaacatatc ggcctggtcg gtgccaatgg tgaaggaaaa tcaaccttta tgagtatcgt
    30001 gactggtaaa atgctgccag atgaaggaaa ggttgagtgg tccaaatatg tgacggctgg
    30061 ttacttggat cagcactctg tccttgctga aagacagtcg gtgcgtgatg ttctccgtac
    30121 ggcttttgat gagcttttca aagctgaagc tcgtatcaat gacctctata tggaaatggc
    30181 tgaagacggt gcggatgttg atgctctcat ggaagaagtg ggagaacttc aagaccgtct
    30241 ggagagtcgt gatttctata ccttggatgc taagattgac gaagtagcgc gtgctcttgg
    30301 tattatggac tttggcatgg atacggatgt aacttctttg tcaggtgggc aaagaaccaa
    30361 ggtgcttttg gcaaaacttc tccttgaaaa gcctgatatt ttgctgttgg acgagccgac
    30421 caactacttg gatgctgagc atattgattg gctcaagcgc tatctccaaa actatgagaa
    30481 tgcctttgtc ctcatttcgc acgatattcc attcctcaat gacgttatta atattgtcta
    30541 tcatgtggaa aatcaacagc tgacgcgtta ctctggtgac tactaccagt tccaagaagt
    30601 ttatgctatg aagaaatctc agctagaggc agcctacgaa cgccagcaga aagagattgc
    30661 agacctcaag gactttgtgg ctcgtaataa agcccgtgtt gcaactcgta atatggctat
    30721 gtctcgtcaa aagaaattgg ataagatgga tattatcgaa ctccaaagtg agaaaccaaa
    30781 accatccttt gatttcaaac cagctcgtac accagggcgc tttatcttcc aagccaagaa
    30841 cttgcaaatt ggttacgacc gtcctcttac taagccttta aatcttacct tcgaacgcaa
    30901 tcaaaaggtt gcgattattg gtgctaatgg tattggaaaa acaactctct tgaagagtct
    30961 cttaggcatt atctcgccaa tcgctgggga agtggagcgt ggagattatt tagaacttgg
    31021 ttattttgag caggaagtag aaggcggtaa tcgccaaact cctcttgaag ctgtctggaa
    31081 tgcctttcct gcccttaatc aagcagaagt ccgtgcagcc cttgcccgtt gtggtttgac
    31141 aaccaaacat attgaaagcc agattcaagt attatcaggg ggagagcaag ccaaggttcg
    31201 tttctgtctc ttgatgaatc gtgaaaacaa cgttttagtg ctggacgagc cgaccaacca
    31261 tttggatgtg gatgcaaagg atgagctcaa acgcgctctc aaagaatata ggggatctat
    31321 ccttatggtc tgccacgagc cagactttta tgaaggctgg atagaccaaa tatgggattt
    31381 taataattta acttaagaat gagagtaaaa gaaatacagt accgaatgtg gatactgtat
    31441 ttttttggtt tttaagattt aaaatcgtag tctttcacca cttcgatgct gtcgattgtg
    31501 atagcagtag ttggcttgtc tttttcatct ttttcggcct tagcaatctt atccacaaca
    31561 tccataccgt caatcacttg accaaagact gggtgtttgc catctagact agggtttcca
    31621 ccttctttgt aggcttcgat aattttctgt ggatacttgc ttgtagggag tttagaagag
    31681 gtatctgtag agttttggtt gatgaagaac tggctgccat tggtgtttgg ttgaccagta
    31741 ttagccatag caagagcacc acggatgtta tacaaataag gagtaatctc gttcttgaaa
    31801 ccagttcctt tgtctttagt cttatccttg tcatgccaga tggactgacc acctgtaccg
    31861 tccccttttg gatctccagt ttggaccata aagccatcga tgacacggtg gaaggtaata
    31921 ccgttatagt agccttcttt ggcgtgagtg aggaaatttt caaccgctag aggagcgagt
    31981 ttagggaaga gtttaatgcg aatatcacct tggcttgtgt ggagaatcac ttcggcttca
    32041 tcttcagcaa cttccttaga tagttgtggg aaattggcgt tttcgtttgt taaagcatcg
    32101 tttaactcct tggcagattg ggcagctact ttggaacttt cttcagcagc aagactggaa
    32161 tcaacataat catcaccacg cagactgcgt tggacgctgc tacacccagc tagggctaca
    32221 gtagacagta aaagaagggt tgctagtttt ttcattctga tcctctcaaa aattcattta
    32281 taaccattgt accctaaaag gaagtggatt tcaaatatta gtagtttaca gaactggctt
    32341 agataatagt tgggatttca tcatcatctt gaaaatcttc aacttcttcc ccagtaaatg
    32401 gtttctgaaa agaacttagt ataaaacggg caattggttc aacaattagg aaatttagag
    32461 gaagagctgc aataaagttt acgaaccagg cgcttagata ggtattgggt gtgatagcaa
    32521 tgccattgta aaaaaagtcc atagaaggac atgaaagtga ccagctaatt cttcttctga
    32581 aaaatgctca tgaagggctt gatccaggtc gcaagatttc attttagaaa gtccagtaac
    32641 tcccttcttc ttcaggatat tctttttcat ggtagtattt agatggtcaa gtgagtcaaa
    32701 agaagtttcg acaagagcat accctttttc taccagagtt tttagatgtt taggggcatc
    32761 aataccataa gtgtactcaa agtattttgg aaaccagatc ttaagaaagc tcgtaaagct
    32821 agccagttct ctaaacgcta agaactagct acaacacagc atttacaaca cttcatggtt
    32881 cacaccatgg ggtgtttttt aatgatttta agcaaaattc acacttaatt gaaagttatt
    32941 taaattagat gaaaatttat tttttgaaaa agtgggaaaa cattgattct aagcgaattt
    33001 tgaatcatat tcgaatggga gtttttaaaa tcatgtttca gtggtaaaag taccaaactg
    33061 gattctccat agtaaaatga tatctcctgc tagtgaatca tctactaata agtccatatt
    33121 tcgcttggga acgggcttgg gacttagaag ccaagtatcc aactctcgtt caggcgatat
    33181 gaagggtttg acttggtgtt ctttataaaa tttttctaaa atagtattca cggatagcat
    33241 ctttcaaaca tttatttcct attctaacaa atttctaaat actttaagaa atttatagtc
    33301 tgtcaagttt ttttcttgac acatgtcaga aatctgctat aatagaacat gtgctaaata
    33361 gctcagctat ttcaccgaaa taaaaaatta aagaaatgag actttaaaaa tggcagttaa
    33421 aatccgtttg actcgtatgg gttctaagaa aaaacctttc taccgtatca acgtagcaga
    33481 ttcacgttca ccacgtgacg gacgtttcat cgaaacagtt ggaacttaca acccacttgt
    33541 tgctgaaaac caagtaactt tgaaagaaga ccgcgttctt gcatggttgg ctaatggagc
    33601 tcaaccttca gacacagtac gtaacatcct ttcaaaagaa ggcgtattga aaaaattcca
    33661 cgattctaaa ttttcaaaat aagtttaaag taggttgaca gatggatacg attgaaaatc
    33721 tcattattgc gattgtgaaa cccttaattt cacaaccaga tgccttaact atcaagattg
    33781 aggatacacc agaatttttg gaatatcatt tgaatcttga tcaaagcgat gtgggtcgtg
    33841 taatcggtcg taagggtcgc actatttctg cgataagaac gattgtctac tctgtcccaa
    33901 ctgaatacaa aaaagtaaga atcgttattg acgaaaaata agaagggcgg gacggatgtc
    33961 tcgctttttt gtgtggaata gaagatatag taaaatgaaa caagaacagg acaaatcgat
    34021 caggacagtc aaatcgattt ctaacaatgt tttagaagta aaggtgtact attctagttt
    34081 caatatacta taaaagattg aacgtttagg caattccaag actacttaat cgaacattaa
    34141 cagcagtctc ggactgatga aggtctcttt atgaagttag tggaggaagt cggaaaagta
    34201 gccgaggttt tgaataggcg ctctggtcga aaagaaggga taggattcga acgaggaact
    34261 tgccagagaa ctggctgata tcatttacta caccgtcgca atcgtagcta ttaatcatat
    34321 tgaccttacc aagactgtct ttgagaaaga caaaaccgca gccgttaatt accaacataa
    34381 acataatttg gaaggattat tgaagggaaa gtagagatgt tgtccccttc ctccaacttg
    34441 agaaaatcct tggaacgtga taaaataaag gataatgatt tttaataatt cattatatag
    34501 aatgagtgga tttctttatg aagaggtttg aagtatctac agaaattggt agcctctctg
    34561 ttacttatca aaagcaaaag aaagtgctag tttgtctaaa cggagcaggt ttgctaccaa
    34621 gttatgaaaa tttttcactt atacttgaaa aacctcctcc tacaattggt tatttgacaa
    34681 ttgattttcc gaacacaggt aggagtccga ttcatgacca agctggaaaa aatctagata
    34741 atcttgcaga tgcggtttat gaagtacttg aagaattagg aatttctgaa tatatacttt
    34801 gtgcacatag ttggagtgga attttagctt gcaaattact cgagaaacca attaagcgtc
    34861 agactttagt agcaattgaa ccgacaacta aaaaagtcat gtttgctgat ttttcagaaa
    34921 atccttatcc aaaaatggaa gagcagatga ggctgattga cgagtgtggt cctgaacttt
    34981 attttaagaa cttaactcaa gcaacattta gtcctgaaac gaataaaaaa atctgggaat
    35041 taatgcaaga aaaaggctta gagttggaaa atcaagatcc agaatttcag atatctggag
    35101 agattactga ggaagatttt gagaatttgt cgatagaatc tcatgtccct gtttttattt
    35161 tttgtcagac ttatagagaa aaagagtaca gagaatcaga atattggact tccaatacta
    35221 aactcatttt aggagggaat caccattatt tacaatggtc agaatcggaa aaaattgcgg
    35281 ctattattcg agaattgtca gaataagatg gaaaaaagga gattacagga gacaagatga
    35341 actactttaa tattgggaaa atcgttaata cgcagggatt acagggtgag atgcgagtct
    35401 tgtctgtgac ggattttgca gaagaacggt ttaaaaaagg agctgagctg gctttgtttg
    35461 atgaaaaaga tcagtttgtc caaacagtga ccatcgctag ccaccgtaaa cagaagaact
    35521 ttgacattat taaattcaaa gatatgtacc atatcaatac tatcgaaaag tacaagggat
    35581 acagtctcaa ggtcgctgag gaagatttga atgacctaga cgatggtgaa ttttactatc
    35641 acgagattat cggtttggaa gtctatgagg gtgatagctt ggttggaacc atcaaggaaa
    35701 tcctgcaacc aggtgctaat gatgtctggg tggtcaaacg aaaaggcaaa cgtgatttgc
    35761 ttttacctta tatcccacca gtggttctca atgttgatat tccaaataaa cgggtcgatg
    35821 tggaaatctt agaagggtta gacgatgaag attgatattt taaccctctt tccagagatg
    35881 ttttctccac tggagcactc aatcgttgga aaggctcgag aaaaagggct cttggatatc
    35941 cagtatcata attttcgaga aaatgctgaa aaggcccgtc atgtagatga tgatccctac
    36001 ggaggcggtc agggcatgtt gctcagagca caacctattt tcgattcctt tgatgctatt
    36061 gaaaagaaaa atccgcgcgt tattctcctt gatcctgctg gaaagcagtt tgatcaggct
    36121 tatgctgaag atttggctca agaggaagag ctaatcttta tctgtgggca ctatgagggt
    36181 tatgatgagc gcattaagac cttggtaaca gatgagattt ccctaggcga ctatgtcctc
    36241 actggtggag aattggcagc tatgaccatg attgatgcta cagttcgcct gattccagaa
    36301 gtgattggca aggagtctag ccaccaagat gatagttttt cttcaggtct tttagaatat
    36361 cctcagtaca cacgtcccta tgattatcga ggcatggtcg tgccagatgt attgatgagt
    36421 ggccaccatg aaaagattcg tcagtggcga ttgtacgaga gtttaaagaa aacctacgag
    36481 cgcagaccgg atttacttga acattatcaa ctgacagtag aagaagaaaa aatgctggca
    36541 gaaatcaaag aaaacaaaga ataaaggaga aacctatgca agtaatcaaa cgtaatggcg
    36601 aaattgctga atttaatcca gataagattt accaagccat cttgaaggca gcccaaactg
    36661 tttatgtttt gacagatgat ttgcgtcaaa atcttgctca agtcactaag aaggtagttt
    36721 tggatttaca agaagccaag gtggaacgtg cgactatcag tatgattcaa tctatggttg
    36781 aacatcgttt attgggcgca ggttacatta ccattgcaga acactacatt tcctatcgtt
    36841 tacaacgtga cttggaaaga agtggttatg gagatcatat cgcagttcat ttacattttg
    36901 aacaaattcg ctaagaaaaa agagtgggat gaagcaacta catctcactc tttcttaaat
    36961 ctattttttt gggctgtttg gacagttgag gggacaaatc gcaggcgttg aatatcgctt
    37021 atacggataa tccggctcac atttttggca aaatttttca cgataatttg ctggccttgc
    37081 tgatcatatt tgatgatatc acctgtaaag cttgtctcag acaagataag gtgaacagcg
    37141 gtttgtttct ggatagcctc ttcaatagtg gctgtaaggg agttggtttc agtctggtca
    37201 ggttggtcat gtccatttaa aaaatcatgt attttatcta gaacttgctg gaatttatgt
    37261 ctcatattgg cctcccttct tctatatcaa tattatataa aattttccta aaatctacaa
    37321 gattttacga ataaactaat gaaactaaaa aaggagaaga aaatggcaga atttacattt
    37381 gaaatcgaag agcacttgtt gactctttct gaaaacgaaa aaggttggac caaggaaatt
    37441 aaccgtgtga gctttaatgg tgcccctgca aagtttgata ttcgtgcttg gagtccagac
    37501 catactaaaa tgggcaaagg gattactctc tcaaatgaag aatttcaaac gatggtggat
    37561 gcctttaaag gcaactaata ctcttcgaaa atctcttcaa accgcatcag ctttgccttg
    37621 ccgtatgtat ggttactgac ttcgtcagtt tcatccacaa cctcaaaaca gtgttttgag
    37681 cagcctgcgg ctagcttcct agtttgctct ttgattttca ttgagtataa gttttcaaaa
    37741 taaaaaaaaa ggatattgag tcatgataac tcgatatcct tttttagtta gtaaagtaag
    37801 cctgattttt aaggcgttga agtaggggac ggctaataaa actaatagcc agaagtttgc
    37861 caaggtctgg aatgataaag ggaagaaccc ccacaacaag agctttttca aatgccattc
    37921 cagctaggaa atgcaagctg agaatcccgc cgacaaagac aagggcatca cccaagaggt
    37981 ttgcaagaaa aatcttaaca acaccactct tgctgttggt tagagaggaa gtaagtccag
    38041 agtaaacgag ataaaaccaa agatagcctg cagtagggcc aactaaagcc tgaaaaccag
    38101 ctccacctcc tgcaaagaca ggaagaccga tagcacctag aagaagatag agtccagcag
    38161 aaagtacagc ctctctcggt ctaaagacag tagcaatcaa gccgattgca aagttttgca
    38221 gagtgaaggg aacaggtcca attggaagac tgatttgtgc caaaacagca atgagagcag
    38281 ccccaatagc agggatagca taaacgtgag cttttttcaa aatagttaac ctcttttcta
    38341 atgtatagta actattatac tcatatagga gtcgatgtca accatttttt aaaaacaagg
    38401 taacaaaaac tgtaacagcc gattttcgtg actagtcaag ttggataatt tttttgttga
    38461 ttcgaaaatt gtctgtatag ataatcctat tttattaata aaaaatatac tagtaaatac
    38521 ttgacaaatt aaaaaataag tgttacatta aaaatgtaaa cggatacatt tagatgtgtt
    38581 caattttaaa aggaggggta gttatgagat attttaacga ctctagatac cataacggtg
    38641 attaaaaacc taaatataat caattcatat taaagtaata tggagggact aaaaagagac
    38701 tattatttaa tcttcatcaa atatttaaat tcaaggagaa gtaaaatgaa aaaaagaatt
    38761 aataagaaag catctgtttt tctagttgca agtgttttca gttttagctt tgctactaca
    38821 gctagtgtcg ttaacgcagt aacggcacac cctgctccaa gtcccattat tgatgtatgg
    38881 gaatatggtg taaatgataa ctatggttat tcgaattact ttgttagttc tccaagtaat
    38941 attggatcaa aatcttcagt aacgaatttt tggggaacag ttaaagctca ggataaaaaa
    39001 gattatggat gggcatattc aagtgcaaca aaatcttgga acgatgttcg cttaaatgca
    39061 tattgggatt attatagatt ttaaaaataa tttatgaaaa caagagaccc aattataaga
    39121 ttgggtctct tgtaatatgg taattgctta tgaaattaaa attatgtatc attggattct
    39181 tcttttgttt gattgctaca attggtctgg tcactattag tgataccgaa atccccatac
    39241 ctttaccaat tgatggagct ttttctatcc aaggaaaaag taatctttct aataacgaaa
    39301 tatacgaaat ggttcgtgac ttatcaaaaa cggaaaaggt taccatttac aagccaatcg
    39361 ttcagagttc gggtcagttg aagtatgtaa attttgatga tgtaaataat gaacaattaa
    39421 agtcagcacc aatagtaggg atgtattaca cacttgggaa aatggatgta gacagtttga
    39481 aaccacttac gatgacggga ctacaaacag tctatatggc ttatccttgg tatataggag
    39541 gaatattaca attcactgga actttaagaa tactgttaat gggttcaatt tatttaactt
    39601 tattagttgt tttatttgtt gttaggacga ggcagatcaa agaaggagtg atacgacgtt
    39661 ctttgggctt gcctatatac gacttaagaa gagagtatgg catttctctt atttttgaac
    39721 tgattatgat ggctttattg atgatttctt acagttcttt tttgggtaat ggtttcttca
    39781 cctatagttc taagttattt ttctctctgc ttttaacgaa ttttatacta tttcaaatca
    39841 ttgatcttat tacttttgtt ttattttggt tgacgattca gattgaaaag cctattgaaa
    39901 ttattaaaaa caaggcaaaa aacaagctta tttttgtcgt atggcttgct attatttcga
    39961 ttatcatcct tgtctcagga gtttttttac aagaaacaaa gagtagtcaa tctagtatta
    40021 acatacagat acagaattta gtaccatggg atacagtaaa agactggaga aggattgagt
    40081 tccttggaat tgaaagtaac tctactaaaa atagagaagt taatgattca gatggtcagt
    40141 atctacagat agttgctgcc ttaaaaaact tagatttctt atatatagaa cggtcttcag
    40201 catatgttcc agatttcatg aaaacttcac atgttataga aaatttttct aaacaattag
    40261 aaaatgacgg gataacgaat ccagaaataa ataaagagtt aatttatatc aaccaaacag
    40321 gtgctaacct acaaaataaa gtgaatggaa caaactatca tcttttagat aataagatag
    40381 caaccatcta tattcctgag aagtggaaag aaaaccagaa atctattgag aatacagttg
    40441 tagcagaaca atttattgga acaaactata caagagaaca gcttgcagtt caaataattc
    40501 ctgatgggga aaaaattttt tattttaatg aggatgctga taataatctt aaaatgaaag
    40561 atattttacc gctggcaaat gtagcagata gcaaagataa tatagttgtt gtgttagata
    40621 cggacaaaat gatggaaaat aataagtttt ctttggctag taacatacta tataaatctc
    40681 tttttagtcc tgaagcggta aaaaaaataa atgagatgac tgtcctgttg aatttctcaa
    40741 tgaatccagt agatgtttac caaattgtga aattaaagat tcaatcctta gagcaccaaa
    40801 ttttactttc acaaatcttg cagaagataa tttacagtat tgtctttata ctcatttatc
    40861 aatatgtcca actttttatt actctaaaac agaatgaata tgtgaaaaaa atcattttgg
    40921 gtctgtcaaa aacatatata gcaatttcaa gtctcaaata ttttatgatg actattacaa
    40981 tggttattct atttacattt cttatgacag ggcaaataga gttgctatat attggagcgg
    41041 cttctctgct agttttgatg ttgtcaatca taatgagttt tagaaaatta tctgaaagct
    41101 acactaaaat tttaaaagga gatgaatcat gacaattgac cttttgaacg tttcaaaaag
    41161 tttcggctca aagaagatct ttacagactt aaatttaata tttgaatctg gaaaaagcta
    41221 tgcattgatt ggaggttctg gctccggtaa aagtaccctt cttaatatta taggaagatt
    41281 agaaaaaatt gacagtggga atgttttagt tgataaacaa gatatttgga agataaaaga
    41341 aagaactttt tttaaaaata ctgttggata tgtatttcag aattattctt taatagataa
    41401 caaaacagtg tatgataatc tgagccttat cactaaagac aaaaaaacaa taactgacgt
    41461 acttgaaaaa gtaggactgt caagtgacta tttacaccaa aaaatatatg aattgtctgg
    41521 agggcaggct caacgtgtag ctattgccag aatgttaatg aaaccatgta aaattatctt
    41581 agcagatgaa cctacaggag ctttagatgg tgagattgga aaagaaatta ttcgtttact
    41641 attgaatgaa acagctgaag ataaatatgt cattatagcg acacatgatc cagctgtcta
    41701 taacgaagtt gatgtgataa ttgacatgaa agatataggg tataaggtat gaaaaagaaa
    41761 atttatattg ctttgatctt tgtaactggg gtactcgcca ttttcttttt tggaaaacaa
    41821 atgattacaa aagaaaatat caataagcca acggtagagt taacaatcta tacgctttct
    41881 tctagtgata cagaaaaatg gaataaagtg agacaagtag aaacggaaga agctatatac
    41941 ttcataactg tgaaagaagt atcatcttca gaagaagtat tttcaaacat cattgcaaat
    42001 ggagctgcta cggggttcgg agttcgtgaa gaagaagtga agaaattcaa taatggttta
    42061 ggagacacca tagaggactc taagcataat aaactaattg aaatagaatt ttttactttt
    42121 tctgatgatg gcgcgggatt tgtggtagca aactttgact acggtaaaga agagttgaat
    42181 tctcagaaaa aagatataaa agaattatat aaaaaaatat atgaatcttt taaagaaaag
    42241 aataaatgat tgtattataa tccttgtatt ttgctatggt ttgttaattg atttttgcat
    42301 atcttacttc aacatactat aaaataaaac ataagaaaac gagtatctcc aactacggaa
    42361 atactcgctt tttgatattt agaagtgttt tttgctttgc ttcttttgtt tcgattaacg
    42421 catggttaca aattcttcag atgcagttgg gtgaattgcc acagttgcat caaagtcagc
    42481 cttggttgct cccattttga tagcaacggc aaatccttga atcatttcat caacgccgta
    42541 gccaattcca tgaagtccga caactttttc ttctgaacca gctgttatga gtttgaaacg
    42601 ggattcttga cggttgcgag tgcaagcaga gtacatagat gcaaagcttg atttataaac
    42661 cttgatttgg tcttgaccgt attctttaat agcttgctct tctgtcaaac caacagttcc
    42721 gatagcaggg tgtgaaaaga caacagttgg aatagttgag taatccattt ttgcagtagt
    42781 ttttccgtta aagagacgtt cagatagggt acgtccggcc ttgattgcaa ctggagtcag
    42841 ttctttctcg cccgttacat cacctagagc atagattccc tcaacaacag tattttggta
    42901 ttcatccact tggataaagc cacgttcgtt cagagtcact ccagcttttt caagttgcaa
    42961 gcccttaacg tttggacggc gacctgtagc ccagataact tggctagctg tgtgactagt
    43021 accatcttcg aaatgaatgg taatgccgtc agtagttttt tctaacttga cagggacttt
    43081 gtgagtgtga agtggtaagt ttgttctttc catttccttg accaaacctt caacgatgta
    43141 ggaatcaaaa ccacgtaaag gacgatcgcg gcgaacaaag agatctgtct tgacaccaaa
    43201 agtgtggagt acgccagcta attcaacggc gatataacca gcgcctagaa tggcaattga
    43261 ctctggaagt tcttcccagg caaatacatc atcagaagag ccacctagct cagcaccagg
    43321 aatattagga atacttggat gggcacctgt agcaatcacg atatgtttag cacgaatcag
    43381 ttcaccattt acgcttacag tatgagaatc tacaaattca gcatgacctt caatcaagtc
    43441 tacaccgttg cgtttaaaac taccatcata agaagaacga gcgcgatcaa tgtaggcttc
    43501 acgattgcga cgtagggttg caaagtcaaa gttaagatca gtagtcttaa agccgtagtc
    43561 ttctccaaat tgatggaaag tctcagcgat ttgcgccccg taccacatga tttttttagg
    43621 aacacaaccg acgttgacac aggttccacc taatttcttt tcctcaataa cggctgcttt
    43681 ggctccatgt tcaccagcac ggttcatggt agcgattcct ccgctacctc caccgatagc
    43741 aatgatatca tattctctca ttgaaaactc ctttgtaatc ttttaaatag tagagcgtct
    43801 tttttgatag ttatatttta ttcttttttt gatttgattg caaaaatctg ctacgcacaa
    43861 aaaattgcaa aaaagcttgc caaataagtc aagatagtgt attatatatc tagtacaata
    43921 gaaaagcaaa attccgaacg attgtttaat cctgaactgt attgtttgct ggagggaaat
    43981 ttggtataat agcaaagtat tgtaaaaaag aaaaggagtt tcattatgaa gaaaaagaat
    44041 ggtaaagcta aaaagtggca actgtatgca gcaatcggtg ctgcgagtgt agttgtattg
    44101 ggtgctgggg ggattttact ctttagacaa ccttctcaga ctgctctaaa agatgagcct
    44161 actcatcttg ttgttgccaa ggaaggaagc gtggcctcct ctgttttatt gtcagggaca
    44221 gtaacagcaa aaaatgaaca atatgtttat tttgatgcta gtaagggtga tttagatgaa
    44281 atccttgttt ctgtgggcga taaggtcagc gaagggcagg ctttagtcaa gtacagtagt
    44341 tcagaagcgc aggcggccta tgattcagct agtcgagcag tagctaaggc agatcgtcat
    44401 atcaatgaac tcaatcaagc acgaaatgaa gccgcttcag ctccggctcc acagttacca
    44461 gcgccagtag gaggagaaga tgcaacggtg caaagcccaa ctccagtggc tggaaattct
    44521 gttgcttcta ttgacgctca attgggtgat gcccgtgatg cgcgtgcaga tgctgcagcg
    44581 caattaagca aggctcaaag tcaattggat gcaacaactg ttctcagtac cctagaggga
    44641 actgtagtcg aagtcaatag caatgtttct aaatctccaa caggggcgag ccaagttatg
    44701 gttcatattg tcagcaatga aaatttacaa gtcaagggag aattgtctga gtacaatcta
    44761 gccaaccttt ctgtaggtca agaagtaagc tttacttcta aagtgtatcc tgataaaaaa
    44821 tggactggga aattaagcta tatttctgac tatcctaaaa acaatggtga agcagctagt
    44881 ccagcagccg ggaataatac aggttctaaa tacccttata ctattgatgt gacaggcgag
    44941 gttggtgatt tgaaacaggg tttttctgtc aacattgagg ttaaaagcaa aactaaggct
    45001 attcttgttc ctgttagcag tctagtaatg gatgatagta aaaattatgt ctggattgtg
    45061 gatgaacaac aaaaggctaa aaaagttgag gtttcattgg gaaatgctga cgcagaaaat
    45121 caagaaatca cttctggttt aacgaatggt gctaaggtca tcagtaatcc aacatcttcc
    45181 ttggaagaag gaaaagaggt gaaggctgat gaagcaacta attagtctaa aaaatatctt
    45241 cagaagctac cgtaatggtg accaagaact gcaggttctc aaaaatatca atctagaagt
    45301 gaatgagggt gaatttgtag ccatcatggg accatctggg tctggtaagt ccactctgat
    45361 gaatacgatt ggcatgttgg atacaccaac cagtggagaa tattatcttg aaggtcaaga
    45421 agtggctggg cttggtgaaa aacaactggc taaggtccgt aaccaacaaa tcggttttgt
    45481 ctttcagcag ttctttcttc tatcgaagct caatgctctg caaaatgtag aattgccctt
    45541 gatttacgca ggagtttcgt cttcaaaacg tcgcaagttg gctgaggaat atttagacaa
    45601 ggttgaattg acagaacgta gtcaccattt accttcagaa ttatctggtg gtcaaaagca
    45661 acgtgtagcc attgcgcgtg ccttggtaaa caatccttct attatcctag cggatgaacc
    45721 gacaggagcc ttggatacca aaacaggtaa ccaaattatg caattattgg ttgatttgaa
    45781 taaagaagga aaaaccatta tcatggtaac gcatgagcct gagattgctg cctatgctaa
    45841 acgtcagatt gtcattcggg atggggtcat ttcgtctgac agtgctcagt taggaaagga
    45901 ggaaaactaa gatgcagaat ctgaaatttg ccttttcatc tatcatggct cacaagatgc
    45961 gttctttgct tactatgatt gggattatta tcggtgtttc atcagttgtt gtgattatgg
    46021 ctttgggtga ttccctatct cgtcaagtca ataaagatat gactaaatct cagaaaaata
    46081 ttagcgtctt tttctctcct aaaaaaagta aagatggttc ttttactcag aaacaatcat
    46141 cttttacggt ttctggaaag gaagaggaaa ttcctgttga accgccaaaa ccgcaagaat
    46201 cctgggtcca agaggcagct aaactgaagg gagtggatag ttactatgta accaattcaa
    46261 cgaatgccat cttgacctat caagataaaa aggttgagaa tgctaatttg acaggtggaa
    46321 acagaactta catggacgct gttaagaatg aaattattgc aggtcgtagt ctgagagagc
    46381 aagatttcaa agagtttgca agtgttattt tgctagatga ggaattgtcc attagtttat
    46441 ttgaatctcc tcaagaggct attaacaagg ttgtagaagt caatggattt agttaccggg
    46501 tcattggggt ttatactagt ccggaggcta aaaggtcaaa aatatatggg tttggtggct
    46561 tgcctattac taccaatatc tcccttgctg cgaattttaa tatagatgaa atagctagta
    46621 ttgtctttcg agtgaatgat accagtttaa ccccaactct gggtccagaa ctggcacgaa
    46681 aaatgacaga gcttgcaggc ttacaacagg gagaatacca ggtggcagat gagtccgttg
    46741 tatttgcaga aattcaacaa tcgtttagtt ttatgacgac gattattagt tccatcgcag
    46801 ggatttctct ctttgttgga ggaactggtg tcatgaacat catgctggtt tcggtgacag
    46861 agcgcactcg tgagattggt cttcgtaagg ctttgggcgc aacacgtgcc aatattttaa
    46921 ttcagttttt gattgaatcc atgattttga ccttgttagg tggcttaatt ggcttgacaa
    46981 ttgcaagtgg tttaactgcc ttagcaggtt tgttactgca aggtttaata gaaggtatag
    47041 aagttggagt atcaatccca gttgccctat ttagtcttgc agtttcggct agtgttggta
    47101 tgatttttgg agtcttgcca gccaacaagg catcgaaact tgatccaatt gaagcccttc
    47161 gttatgaatg agatcaacaa gatggacact cgtctatctt gtttttgtat ggatttccct
    47221 atcgaaattc attaaaaatg tgatataatg aagtgttaga aaaacaggtt tcatttgcct
    47281 ggaaaggaaa aattatgtct gaaaaaaatt tttatattac aacgccgatt tactatccat
    47341 ctgggaaact tcatatcggt tctgcctaca caactatcgc atgtgatgtc ctagcacgtt
    47401 acaaacgcct gatgggctac gatgtatttt atctgacagg tcttgatgaa catggtcaga
    47461 aaattcagca gaaagcggaa gaagctggta ttacacctca agcctatgtt gatggaatgg
    47521 cggttggagt taaagaactc tggcaattac tagatatctc atacgataaa tttatccgta
    47581 caactgatga ctaccatgaa aaagttgtcg cacaagtctt tgaacgctta cttgctcaag
    47641 atgatatcta cttgggtgaa tactctggtt ggtattcagt atcagacgaa gaattcttta
    47701 cagaaagcca gctggcagaa gttttccgtg atgaagctgg aaatgtgact ggtggtattg
    47761 ctccatcagg tcatgaggtt gaatgggttt ctgaagaatc atacttcctt cgccttagca
    47821 aataccaaga ccgtttggtc gaatttttca aagctcatcc tgaatttatc acgccagatg
    47881 gtcgccttaa tgaaatgcta cgcaacttca tcgagccagg tttggaagat ttggcggtat
    47941 ctcgtacaac ctttacatgg ggagtgcctg tcccatcaaa tccaaaacac gttgtctacg
    48001 tttggattga tgcccttctt aactatgcga cagctcttgg ctacgctcaa gacgaacatg
    48061 gtaactttga caagttctgg aatggaacag tcttccatat ggtaggaaaa gatatccttc
    48121 gcttccactc tatctactgg ccaatccttc ttatgatgtt ggatgttaaa ttacctgatc
    48181 gtttgattgc ccatggttgg tttgtcatga aagacggaaa aatgtctaag tcaaaaggga
    48241 atgtcgttta ccctgaaatg ttggtagagc gttatggact agatccactt cgttactacc
    48301 tcatgcgtaa ccttccagtt ggttcagacg gaacctttac tcctgaagac tatgtcggcc
    48361 gtatcaacta tgaattggct aatgaccttg ggaacctcct taaccgtacg gtttccatga
    48421 ttaataagta ctttgatgga caaatccctg cctatgtaga aggtgtgact gaatttgatc
    48481 atgttcttgc tgaggttgca gaacaatcaa tcgcagactt ccatacacac atggaagcag
    48541 ttgactatcc acgtgcgctt gaagcagtct ggactctgat ctctcgtacc aataaataca
    48601 tcgatgagac tgcaccatgg gtcttggcca aggatgaagc tcttcgtgac caattggcaa
    48661 gtgtcatgag ccacttggca gccagcattc gtgtagttgc tcacttgatt gaaccattta
    48721 tgatggaaac tagtcgtgca gttttgactc aacttggttt ggaagaagtt tctagtcttg
    48781 aaaacttgag tttggctgac ttcccagcag atgtgactgt agttgccaaa ggaacaccta
    48841 tctttccacg tctaaatatg gaagaagaaa tcgcctatat caaggaacaa atggaaggca
    48901 ataaaccagc agtcgaaaaa gaatggaatc cggacgaagt tgagctcaaa ctaaacaagg
    48961 atgaaatcaa gtttgaagac tttgacaagg ttgaaatccg tgtcgcagaa gtcaaagaag
    49021 tgtctaaagt agaaggttca gataagttgc ttcaattccg cttggatgct ggtgatggag
    49081 aagatcgtca gattctttca ggaattgcaa aatactatcc aaatgaacaa gaattggtcg
    49141 gcaagaaagt tcaaatcatt gctaacctca aaccacgtaa aatgatgaaa aaatatgtca
    49201 gccagggtat gattctctca gctgaacatg atggcaaatt aacccttctc acagttgatc
    49261 cagctgtacc aaatggaagt gtgattgggt aaaagtagac aggactagtt caggctagtt
    49321 ctgttttttt atttatactc aatgaaaatc aaagagcaaa ctaggaagct agccgcaggt
    49381 tgctcaaaac acagttttga ggttgtagat gaaactgacg aagtcagctc aaaacacagt
    49441 tttgaggttg tagatgaaac tgacgaagtc agtaaccata cataaggtag ggcgacgctg
    49501 acgtggtttg aagagatttt cgaagagtat taactattat gctttacaaa ctagtgtaga
    49561 agtgatatac tataggtgaa gttactagta ggtattacaa aatagattag aagggaaaag
    49621 tgatgaaaga aactcagcta ttaaaaggtg ttcttgaagg ttgtgtcttg gatatgattg
    49681 gtcaaaaaga gcggtatggt tatgagttgg ttcagacttt gcgagaggct ggatttgata
    49741 ctatcgttcc aggaactatt tatcctttgt tgcaaaagtt agaaaaaaat caatggataa
    49801 gaggcgacat gcgcccgtcg ccagatggtc cagatcggaa gtatttttca ttaatgaaag
    49861 aaggagaaga gcgtgtctca gtcttttggc aacaatggga cgatttgagt caaaaagtag
    49921 aagggattaa gaatgggggt taaaccatga agaaaatgaa gtattacgaa gaaacaagcg
    49981 ctttgctaca tgagttttct gaggagaatc aaaagtattt tgaggagttg tgggaaagtt
    50041 ttaatcttgc tggatttctc tatgatgaag actatctcag agagcagatc tatttgatga
    50101 tgctagattt ctcagaagca gaacgagatg gcatgagtgc agaggattat ctaggtaaga
    50161 atcctaaaaa aataatgaaa gagattctca agggagcacc tcgcagttct atcaaagagt
    50221 cccttttgac gccaattctt gtcctggcgg tattacgtta ttatcaacta ctaagtgatt
    50281 tttctaaagg tcctctatta acagtcaatt tgctcacatt tttagggcaa cttcttattt
    50341 ttctgattgg atttggactt gtggccacaa ttttacgaag aagtttagtc caagattctc
    50401 ctaaaatgaa aattggcact tacattgttg ttgggactat agttcttcta gttgttttag
    50461 gatatgtagg aatggcaagc ttcatacaag aaggagtctt ttatattccg gctccctggg
    50521 atagtttgtc tgtctttacg atttcgctag ttatcggtat ttggaattgg aaagaagcgg
    50581 tctttcgtcc atttgtcagt atgattattg cccatcttgt ggtgggttct ctgctccgtt
    50641 attatgagtg gatgggaatt tcaaatgttt tccttacaaa agttattcct ttagctgtcc
    50701 tctttattgg aatctttgtc ttgttccgtg ggtttaagaa gataaaatgg agtgaagtat
    50761 agtcaaaaag ccgttgcaaa gcggtttttt gttataatga agggaagaat gttagaaatt
    50821 aaaggagaaa aatttgatga gatacataac tcttggtcaa gatgacaaag aattatcaga
    50881 aattgttctc ggaatgatga gaataaaaga taaatctgta aaagaagttg aagagcttgt
    50941 agaaacagca ctttctgttg gaatcaatgc cttcgacttg gctgatattt atggtcgtgg
    51001 tcgttgtgaa gaactgttag gtcttgtcct aaaaaatcgt ccagatttaa gagaaaagat
    51061 gtggattcag tccaaatgtg gcattcgcat tgaagaattt acctattttg atttttctaa
    51121 ggactatatt ataaaatcag tagacggtat tttgcaaaga ttgaagattg atcatctaga
    51181 tagcttgctc cttcatcgac cagatgcttt gatggaatct gaccaagtag cagaagcctt
    51241 tgatctcctt tataaacaag gtaaagttcg agattttgga gtttctaatc aaaatcctat
    51301 gatgatggag ttgcttaaaa aagatgtcaa gcagccgtta gctgttaatc agctacaatt
    51361 gagtgcggct tttactccag gatttgaatc agcttttcat gttaatatgg aagatagtca
    51421 agcagctatg cgagatggca gcatttttga atattgccaa ttacacgatg tggtcattca
    51481 agcatggtct gtcttgcaat tcgggtattt taaagggaac tttgttggaa atgagaaatt
    51541 tcaagcttta aatcaagtac ttgatcgttt agctattaaa tatggagtaa cctcttcaac
    51601 tattgccatt tcttggatat tgcgttatcc agcaaaaatg caggcagtcg taggtacaac
    51661 aaatcctaag cacttgagag aagttagccg agcggcaaac tttagcttaa caagaaaaga
    51721 atggtatgaa atttatcttg ctgcagggaa taatttgccg taagtagtag caggtttgaa
    51781 taactcacag tcaaaaagcc gtataaagtg gttttttgct ataattaaat gaagaatgta
    51841 gaattaaagg agaaaaacat gacatttgaa gagatcctgc ctgggttaaa ggctaagaga
    51901 aaatatgtac gaactggttg gggaggtgcg gaaaactatg tccaactctt tgataccatc
    51961 gagcaaaatg ggcttgcact tgaaatgaca ccttatttcc taatcaacgt ttctggagaa
    52021 ggagaaggtt tttccatgtg gagcccgaca gtttgtgatg ttttggcaac ggattgggta
    52081 gaagtgcatg actaaacgtg tactcattac aggagtgagt tcagggatcg gattggctca
    52141 agctcgcctc tttttagaga agggctatca agtttatgga gttgaccaag gtgaaaagcc
    52201 actcttagag ggtgattttc actttttaca gagagatttg accttggact tggaacctat
    52261 ttttgactgg tgccctcagg tggatgtttt gtgtaatact gccggagttt tggatgctta
    52321 caaaccactg ttggaacaaa cggcgcagga cattcaagag atttttgaaa tcaactacat
    52381 tattccagta gagttgactc ggtattattt gacacaaatg ctggaaaata aaaagggaat
    52441 catcatcaat atgtgttcca ttgcttctag cctagcaggt ggaggtggtc acgcctatac
    52501 ttcatccaag catgccttgg ctggcttcac caagcagttg gctctagact atgctgaagc
    52561 taggattcag gtctttggta tcgctccagg agcagtcaag acagctatga ccgctgcgga
    52621 ttttgagaca ggtggcttag ctgactgggt ggctagtgaa accccaatca agcgctggat
    52681 tgaaccagag gaagtggcag aagtcagtct ctttttggcc agtggaaagg catctgccat
    52741 gcagggacaa attctgacaa tagatggtgg ctggtctttg aagtaggagg agttggatgg
    52801 aaatcaaaaa tcactttggg gtctactgtg tttgctttga aaatggaaag ttactttgca
    52861 ttgaaaaaac gagaggccct tatcaacatc ggtatgatct acctggaggc agtcagcaac
    52921 ttggtgaagg actgacggaa acgctgacta gagaagttat ggaagagacg ggatttactg
    52981 ttagaagcta ctctaatcct cgaatctacg atgttttcgt cagggaagag ttaaaaaatt
    53041 ttatggttca ccatgtcata gccttgtatg atgttgaaat gaatgagagt gcacctcaag
    53101 ttacgatttc ggaagctgtg tctgatggtg cgaatgattc acttggatat atttggatgg
    53161 atattcaaga gattacagaa gaaaatgcat cgccattagt cttgaaggtt aagtctgaat
    53221 tattaggatt gccagaactg gacaagactt cttacatgaa ttggaaggtg aagtagaggg
    53281 ataatggaac tatttaaaac atggaagaaa aatatggttc tctatggtct taaatctcaa
    53341 attggaactg tctaccgaaa caatgatagg acaacaagct tttatgatgt tgggaatttt
    53401 ctatacctag caggggagtt ggattccaga ttttgggaag attttgttag aaaatatggt
    53461 ttagattata agattattat ttcagaaaat actaattggc aagattttct gcatcgaaaa
    53521 gtggggctaa attcttttac tcgctattct tttaaagata aggcaaattt tcaagttgaa
    53581 tttttaaata atctagttac tcatttagag gaaggttaca atattgtgcc tattgataat
    53641 catatttata actgcttttc tacggaagaa tggtcacagg atttacaggg ggattttgag
    53701 tcctatcagg attttgtttt aaaaggtgga tttggctttg tgattcttaa aaataatgaa
    53761 ctgattgctg ggatttcctc agggttagtt taccgtaaag cagttgaagt ggaagttgca
    53821 actagaccaa acgaacaagg aaatggattt gctaaaaagc ttggtgctgc aatgattcta
    53881 gagagtttaa atagagatat gtttccactt tgggatgctc ataatgaggc ttccaaaaaa
    53941 gtagcagaat ttttaggata tgagttatct gaaccttatg aagcttttga actagaggaa
    54001 attttgatat aattatatat gatattgtat cttttaagac gaggtgaatg gctatgagaa
    54061 atcaacttgc ccttagtggc gaaaaaattc ttgaaaaaat ttatcctcaa ctatttcacc
    54121 acgtcggcat gattcgtggg gaatatttgt tgagagagct taatcaaaac atcatattag
    54181 caagttgtca gcaatttgta aaagattatc tagagactat ctgctccctg tactcagatg
    54241 aagaagtttg gtatcgtttt tctgaattaa cgaatacaga agccaattgt ttagtgggga
    54301 ctagagagtt ttttgacgaa gggcatccct tgtttggcta tagaggaacc aggcgtttac
    54361 tggcgtgttt ggatgaattt caggctgaag cacatgtcgt tacagaagtt tatcaaacca
    54421 atcccaatct atctcttatc tttccttttg tcaatgatgc cgaccaatta aaacaagcta
    54481 ttacagtatt gcgtcagcag ggttttactg ggaaagtcgg aacgatgatt gaattaccgt
    54541 cagcgtattt tgacttatct agtatactgg aaacgggcat ttcaaagatt gtagttggaa
    54601 tgaatgattt gacttccttt gtttttgcga ctatgagaaa cagtcaatgg catgatatgg
    54661 aaagtccaat aatgttagat atgctaagag atatgcagga taaagcaaga aagaacaaga
    54721 ttgattttgc tgtagcaggc tatctgaata cttctttcat acaaaaaatg aatcagttgg
    54781 gtatcaagtg cattatccac tacagttcta ttccagagat ttttgattta gagattgacc
    54841 atccagatca tcttaaacac ataaaagaag aaagtaaaaa attacaaagg agtacccatg
    54901 ataccgcaag aaatgtggaa taaatacaag caaatcaatc ctttgatcgg agatgaaatc
    54961 gatgcttggg cttttggagt tgaaccagat cttttagcgg atttggtgtt taaaggagaa
    55021 aagacagcaa cagcatcagc ctatgacctc tatgtactag aagacgaacc acttccccaa
    55081 gtagggacct tcgatatcat tttagatagt caaaatcagt ctgtctgcat tgtcgaaatt
    55141 acaaaggttt ctgttgaact cttcaatcaa gtttctgcgc aacatgcctt taaggaaggt
    55201 gagggagaca aatcacttgc ctattggcgc caggttcatg aggacttttt cacagactgt
    55261 ttgggtgaag tagggctgac ttttacacct gaaagcaagg ttgttttaga agaatttcgc
    55321 aaggtctacc cactgtagac tattagaagg aagaaagttt tggaaatcgc tgtccaatcc
    55381 ttttttttca agcaaaatat gatataataa gtttgtttga agaagagcag cagctcttaa
    55441 acttagaata ggagaaaact atgcaagcag ttgaacattt tattaagcaa tttgttcctg
    55501 aacattatga tttattttta gatttgagtc gtgagaccaa gactttttct gggaaagtga
    55561 ccatcactgg tcaagcacag agtgaccgca tctccctcca ccaaaaagac ttggaaatca
    55621 cctctgtaga agttgcaggt caagctcgtc catttacagt tgaccatgac aatgaagccc
    55681 ttcatatcga attggctgag gctggtcaag ttgaattggt tcttgccttt tctggtaaaa
    55741 ttacagacaa catgacaggg atttaccctt cttattatac agttgatgga gtcaagaagg
    55801 aggtcttgtc tactcagttc gagagccatt ttgcgcgcga agctttccca tgtgtggatg
    55861 agcctgaagc caaagcaact tttgacctct ctcttcgctt tgaccaagca gaaggtgaat
    55921 tggccttgtc aaacatgcca gaaatcgatg ttgaaaaccg taaggaaaca ggtatctgga
    55981 agtttgagac aacacctcgc atgtcttctt acttgttggc ctttgttgct ggtgatttgc
    56041 aaggggtgac cgctaaaact aaaaatggta ccctggtagg tgtctactca accaaagcac
    56101 atccactttc aaatcttgat ttctcactgg atatcgctgt tcgctctatc gagttttacg
    56161 aagattacta tggagttaag tatccaattc ctcaatctct ccacatcgcc cttcctgact
    56221 tctcagctgg tgctatggaa aactggggtc ttgtgaccta ccgtgaagtt tacttggttg
    56281 tcgatgagaa ctctacattt gctagccgtc aacaagttgc ccttgttgtg gcccatgaat
    56341 tggctcacca atggtttggg aacctcgtga ctatgaaatg gtgggatgac ctttggctca
    56401 atgaaagttt cgctaatatg atggaatacg tctgtgtgga taccatcgaa ccaagctgga
    56461 atatctttga agatttccaa acaggtggag tacctcttgc tcttgaacgt gacgctactg
    56521 atggcgttca gtctgtccac gtcgaagtta aacatccaga tgaaatcaat acactctttg
    56581 acggcgctat cgtctatgcc aaaggaagcc gtctcatgca catgcttcgc cgttggctag
    56641 gagatgctga ttttgctaaa ggtttgcatg cctactttga aaaacaccaa tacagcaaca
    56701 ccattggtag tgacctttgg gatgcccttg gtcaagcgtc aggacgtgat gtcgcagcct
    56761 tcatggattc ttggttggaa cagcctggtt acccagttct tactgtcaaa gttgaaaatg
    56821 atgtcttgaa gatttcacaa aaacaattct tcatcggtga gaacgaagac aagaaccgtc
    56881 tctgggtggt gcccctcaat agcaactgga aaggcttgcc tgatacactc gaaactgaaa
    56941 gtatcgaaat ccctggctac gcagctcttc ttgctgaaaa tgaaggagct cttcgtctca
    57001 acactgaaaa tactgcccac tatattaccg actatcaagg agacttgtta gaagctgttc
    57061 ttgctgagct agagacactt gataacacaa gcaaactgca aattgttcaa gaacgtcgtt
    57121 tgttggctga ggcagggcac atttcttatg cagacttgct tccagttctt gataaacttg
    57181 ctaaggaaga gtcttatctg gtggtttcag ctgtttctca agtgatttca gcccttgagc
    57241 gctttattga tgaaggaacg gatgctgaaa cagccttcaa aggactggtt gctaaattgg
    57301 ctcgtcataa ctatgaccgt cttggttttg aagctaaaga cggagaatca gatgaggatg
    57361 aattggttcg tcagctggct gtttcgatga tgattcgctc aaatgatgca gaagctcgtc
    57421 aagtcgctag ccaaatcttc gcaacacaca aggagaatct tgcagaactc ccagcagcta
    57481 ttcgttcaca agttctgatt aatgagatga aacatcatga gactaaagac ttgttagcac
    57541 tttatcttga tacttatact cacgcaacag atgctgtctt taaacgccag ttggcagcag
    57601 ctcttgcata cagtacagat gcggataata tccaaaactt gattacttct tggaaggaca
    57661 aatttgtggt caaaccacag gacttgtctg cttggtatta ccaattccta gctcatcaag
    57721 caactcagaa aacagcttgg tcttgggcgc gtgaaaactg ggcttggatt aaggcagccc
    57781 ttggaggaga tatgagcttt gatagctttg ttatccttcc tgctcatgta tttaagactc
    57841 agcaacgctt ggcggaatac aaggagttct ttgagccgca actttctgac cttgctctta
    57901 gccgtaacat cggtatggga atcaaggaaa ttgcagcacg tgttgacttg attagccgtg
    57961 aaaaagctgc agtcgaagca gttgttcttc aatacggaaa tgcataaata agcctaaaat
    58021 aaaaagaaa
//
LOCUS       DAVLBE010000007        57278 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.007, whole genome shotgun sequence.
ACCESSION   DAVLBE010000007 DAVLBE010000000
VERSION     DAVLBE010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 57278)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 57278)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57278
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.007"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            49..1296
                     /locus_tag="VXB91_000449"
     CDS             49..1296
                     /locus_tag="VXB91_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HEV0469958.1"
                     /translation="MKLLFRNPAYRILTLSRFFNAFGASIFNLVFIVYASTLSQASFA
                     VAMANIVMILPTLFTVFVGIRADYTRDKVKWMVYSGLFQAVLFFLAALVVQQASLFAF
                     SSLCLINVISDVISDFAGGLRMPLIKEKVAEDDLMEAYSFSQFITYISAIGGQAFGVW
                     LLALSVNNFSLVAGINACFFLVSATILFLGKSKLSLSMSSADGENLKNEKLSIKDQFL
                     TIYRNLRLVFLKSGQKNFGFMLFAVLLINSLGGALGGIYNIFFLSHSLLNFSYTEALF
                     INQFCVLVAIIISSLTGNDYFGKQSLPRLMMWATVGLSLVGLANLFNQVVLGLLFLFF
                     TLYVSGKVQPKISAMLMKNLAPEVLARTSNFLGLLFTLSIPVGTACFSLVAVWNIQLT
                     WMLFVGLSLLAIFLTILNLKNDI"
     gene            1374..2663
                     /locus_tag="VXB91_000450"
     CDS             1374..2663
                     /locus_tag="VXB91_000450"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HEV0469959.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETISMAAYFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKVA
                     VENAPSILDFLDEESQTHFDAVRQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVAYFGGPETAGFGFGLGVERLLLILEKQGVALPIENALDVYIA
                     VLGDGANVKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFAAKTLITLGESEVES
                     GQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ"
     gene            2918..3232
                     /locus_tag="VXB91_000451"
     CDS             2918..3232
                     /locus_tag="VXB91_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0469960.1"
                     /translation="MWVLGFILFMIFFYSNNSKKIKKLENKIKKLERKEKGNAEMSRL
                     FQEMIGKEPIITGVYIGPDNWEVVDVDEEWVKLRRVDNTGKEKFKLQRIEDIQTVEFD
                     GE"
     gene            3242..3448
                     /locus_tag="VXB91_000452"
     CDS             3242..3448
                     /locus_tag="VXB91_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0469961.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            3448..3645
                     /locus_tag="VXB91_000453"
     CDS             3448..3645
                     /locus_tag="VXB91_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0469962.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNLYQSDQFVWVYFA
                     LIPVIEWIEKKSKNLASEKGE"
     gene            3648..4370
                     /locus_tag="VXB91_000454"
     CDS             3648..4370
                     /locus_tag="VXB91_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HEV0469963.1"
                     /translation="MKKKRRLLFLMSIVLGMFVGMFKARVESHEIILDVKALMPWISA
                     ICLLIGFISMFLTFNFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAFNITG
                     VAIPLAIFISLSEVIILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLEFFAT
                     PKDVLNYINSYDEGERQANLEQSFRILFQLHQYVLPALYIFLIIISFLTGEIQLLAFL
                     LVGAIHVYINVMQLPMVKRYFK"
     gene            4382..5023
                     /locus_tag="VXB91_000455"
     CDS             4382..5023
                     /locus_tag="VXB91_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0469964.1"
                     /translation="MKLLKNLGWILLALLSFLFIYGFIQGLATASLALGASPYAVTLL
                     YVAFAGVYVYGIYKWYQKAPVHIEKSGFNRFIWLPVLVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYISRKGLVYSISLHALNNLVGFLMILML"
     gene            5041..5271
                     /locus_tag="VXB91_000456"
     CDS             5041..5271
                     /locus_tag="VXB91_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0469965.1"
                     /translation="MKRVILLAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
     gene            5307..5387
                     /locus_tag="VXB91_000457"
                     /pseudo
     CDS             5307..5387
                     /locus_tag="VXB91_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            5668..7431
                     /gene="aspS"
                     /locus_tag="VXB91_000458"
     CDS             5668..7431
                     /gene="aspS"
                     /locus_tag="VXB91_000458"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HEV0469966.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEQEIQDITEGLIARVMKETKGIEVTLPFPRMKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEAPAVKAIVVKGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALALEDKDLVLFVADT
                     LEVANATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSTEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETNKTN"
     gene            7409..8350
                     /locus_tag="VXB91_000459"
     CDS             7409..8350
                     /locus_tag="VXB91_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEV0469967.1"
                     /translation="MKQTKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINSLFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(8470..8550)
                     /locus_tag="VXB91_000460"
                     /pseudo
     CDS             complement(8470..8550)
                     /locus_tag="VXB91_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(8686..9672)
                     /locus_tag="VXB91_000461"
     CDS             complement(8686..9672)
                     /locus_tag="VXB91_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV0469968.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNDNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
     gene            complement(9682..10482)
                     /locus_tag="VXB91_000462"
     CDS             complement(9682..10482)
                     /locus_tag="VXB91_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HEV0469969.1"
                     /translation="MLPYPFSFFSSILGFRKPLSKRFGLNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTNEVVQDLSEHATIVDGTLTYTGTVSQASSVVIG
                     PSQIKELPKNLQLHFDTNELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRVYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFRTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            complement(10735..11577)
                     /locus_tag="VXB91_000463"
     CDS             complement(10735..11577)
                     /locus_tag="VXB91_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0469970.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHNWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            complement(11579..12871)
                     /locus_tag="VXB91_000464"
     CDS             complement(11579..12871)
                     /locus_tag="VXB91_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0469971.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGDKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            complement(12982..14253)
                     /locus_tag="VXB91_000465"
     CDS             complement(12982..14253)
                     /locus_tag="VXB91_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV0469972.1"
                     /translation="MSSKFMKSTAVLGTVTLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKVTLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIVGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            14803..16320
                     /gene="malQ"
                     /locus_tag="VXB91_000466"
     CDS             14803..16320
                     /gene="malQ"
                     /locus_tag="VXB91_000466"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HEV0469973.1"
                     /translation="MKKRQSGVLMHISSLPGAYGIGSFGQSAYDFVDFLVRTKQRYWQ
                     ILPLGATSYGDSPYQSFSAFAGNTHFIDLDILVEQGLLEASDLEGVDFGSDASEVDYA
                     KIYYARRPLLEKAVKRFFEVGDVKDFEKFAQDNQSWLELFAEYMAIKEYFDNLAWTEW
                     PDADARARKASALESYREQLADKLVYHRVTQYFFFQQWLKLKAYANDNHIEIVGDMPI
                     YVAEDSSDMWANPHLFKTDVNGKATCIAGCPPDEFSVTGQLWGNPIYDWEAMDKDGYK
                     WWIERLRESFKIYDIVRIDHFRGFESYWEIPAGSDTAAPGEWVKGPGYKLFAAVKEEL
                     GELNIIAEDLGFMTDEVIELRERTGFPGMKILQFAFNPEDESIDSPHLAPANSVMYTG
                     THDNNTVLGWYRNEIDDATREYMARYTNRKEYETVVHAMLRTVFSSVSFMAIATMQDL
                     LELDEAARMNFPSTLGGNWSWRMTEDQLTPAVEEGLLDLTTIYRRINENLVDLKK"
     gene            16346..18604
                     /locus_tag="VXB91_000467"
     CDS             16346..18604
                     /locus_tag="VXB91_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan phosphorylase"
                     /protein_id="HEV0469974.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVRSSR
                     SYQVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIDLDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINPNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGEENIYIFGEDSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(19648..20220)
                     /locus_tag="VXB91_000468"
     CDS             complement(19648..20220)
                     /locus_tag="VXB91_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0469975.1"
                     /translation="MNKLMKFISVFLTSIVLIVSAIPSVSAVYASEQVSQIETNMELQ
                     PVTSLTEEQINTLANEIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGIT
                     VNQMGALLDTAIALALGGTTAGLANLIKVKGKHAAKSAIRSAISRYLGSWFVNDVALE
                     FAMNLLSPGTYLAQLWDKNDAIPNNGRINF"
     gene            complement(20842..21690)
                     /locus_tag="VXB91_000469"
     CDS             complement(20842..21690)
                     /locus_tag="VXB91_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEV0469976.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLAPQIKQSANYNKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAN
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSQLTEITIEAEI
                     LVGKAF"
     gene            21842..22120
                     /locus_tag="VXB91_000470"
     CDS             21842..22120
                     /locus_tag="VXB91_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0469977.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            22122..24185
                     /locus_tag="VXB91_000471"
     CDS             22122..24185
                     /locus_tag="VXB91_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEV0469978.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRIRVTD
                     NQMNSRILQLIELMKKSEENKKTKQRYFIKMADKVVKYNFLGAGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLVRTKELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWLSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(24263..25519)
                     /locus_tag="VXB91_000472"
     CDS             complement(24263..25519)
                     /locus_tag="VXB91_000472"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HEV0469979.1"
                     /translation="MHIFDELKERGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADENNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQELDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            25661..28126
                     /locus_tag="VXB91_000473"
     CDS             25661..28126
                     /locus_tag="VXB91_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEV0469980.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLGFLGGMLGAGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMNKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYRMLREKGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNERFALDPSVVKSEVLKSTGQKPGKVS
                     VEGKEVEVTGSTVTSYWANKSGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSSRARR"
     gene            28191..29102
                     /locus_tag="VXB91_000474"
     CDS             28191..29102
                     /locus_tag="VXB91_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEV0469981.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSLVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCVEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVAVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIALIILPMIFLSIEEAKESR"
     gene            29332..30030
                     /gene="dapD"
                     /locus_tag="VXB91_000475"
     CDS             29332..30030
                     /gene="dapD"
                     /locus_tag="VXB91_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HEV0469982.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVRVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            30098..31228
                     /locus_tag="VXB91_000476"
     CDS             30098..31228
                     /locus_tag="VXB91_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HEV0469983.1"
                     /translation="MLDLIQTRRDLHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFASQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEDDAFGDWLPDQFYGLHVRPDLK
                     VGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            31240..31779
                     /locus_tag="VXB91_000477"
     CDS             31240..31779
                     /locus_tag="VXB91_000477"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HEV0469984.1"
                     /translation="MKSELRKQVLHEMKAISQEQKQAIDQALTERILQHPFYQEAKVI
                     ATYLSFSHEFQTRELIEQALKDGKKVLIPKTYPKGRMDFVVYDPQQLVKTAFALLEPQ
                     GDLEVVDASQIDLIHVPGLAFTTDGYRIGYGGGYYDRYLEHFSGHTLSTVHPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            31763..32440
                     /locus_tag="VXB91_000478"
     CDS             31763..32440
                     /locus_tag="VXB91_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HEV0469985.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIVLRYATRNPYIQQLGQSYLTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRMYNTSQRLGAVVLFVGLAILL
                     FYKGMGM"
     gene            complement(32512..33411)
                     /gene="galU"
                     /locus_tag="VXB91_000479"
     CDS             complement(32512..33411)
                     /gene="galU"
                     /locus_tag="VXB91_000479"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEV0469986.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDKTTDMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMDDYERTHAST
                     IAVMPVPHDEVSAYGVIAPQGEGKDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEI
                     FQILENQAPGAGNEIQLTDAIDTLNKTQRVFAREFNGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            complement(33433..34449)
                     /locus_tag="VXB91_000480"
     CDS             complement(33433..34449)
                     /locus_tag="VXB91_000480"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HEV0469987.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     HHTNKHYFKDVVLDENIIAYTDLAETLKNVDAILFVVPTKVTRLVAQQVAQTLDHKVI
                     IMHASKGLEPDSHKRLSTILEEEIPEHLRSDIVVVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQELFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            34661..35101
                     /locus_tag="VXB91_000481"
     CDS             34661..35101
                     /locus_tag="VXB91_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0469988.1"
                     /translation="MREFGEKIKRLRLAKKISRSEFCGDESELSIRQLIRIENGESRP
                     TLTKLKYIAERLEVEDYKLMPSYIELDKEYLELKYFLMRTPTYEDETIAQKKESVFDK
                     IFEEYYDRLPEEERFIIPNYSYLALANYTVQKLPEKLVEILSFW"
     gene            complement(35224..35640)
                     /locus_tag="VXB91_000482"
     CDS             complement(35224..35640)
                     /locus_tag="VXB91_000482"
                     /inference="COORDINATES: protein motif:HMM:NF025080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0469989.1"
                     /translation="MTNLSSVDSEELFQFYRERGNAENFIKERKAGFFGDKTDSSTMI
                     KNEVRMMMGCLAYNLYLFLKQLAGDEVKALTIKRFRRLFLHIAGKYVSTARRHILKFS
                     SLYAYSKQFQALFDTICQINLILPVPYRARGQGKTA"
     gene            complement(35708..36358)
                     /gene="phoU"
                     /locus_tag="VXB91_000483"
     CDS             complement(35708..36358)
                     /gene="phoU"
                     /locus_tag="VXB91_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEV0469990.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKALLALASKDKEMAEL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSFSMLADLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            complement(36373..37125)
                     /gene="pstB"
                     /locus_tag="VXB91_000484"
     CDS             complement(36373..37125)
                     /gene="pstB"
                     /locus_tag="VXB91_000484"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEV0469991.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWEEVKDDLKKSAMSLSGGQQQRLCIARA
                     LAVEPDILLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            complement(37127..37942)
                     /gene="pstA"
                     /locus_tag="VXB91_000485"
     CDS             complement(37127..37942)
                     /gene="pstA"
                     /locus_tag="VXB91_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEV0469992.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDSMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            complement(37935..38798)
                     /gene="pstC"
                     /locus_tag="VXB91_000486"
     CDS             complement(37935..38798)
                     /gene="pstC"
                     /locus_tag="VXB91_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEV0469993.1"
                     /translation="MIKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFMANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRSFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            complement(38916..39791)
                     /locus_tag="VXB91_000487"
     CDS             complement(38916..39791)
                     /locus_tag="VXB91_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate-binding protein"
                     /protein_id="HEV0469994.1"
                     /translation="MKFKKMLTLAAIGLSGFGLVACGNQSAASKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGEYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            complement(39958..41289)
                     /locus_tag="VXB91_000488"
     CDS             complement(39958..41289)
                     /locus_tag="VXB91_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HEV0469995.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMALTWISKGIGLFLLALSLGQGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSGLKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            complement(41290..41997)
                     /locus_tag="VXB91_000489"
     CDS             complement(41290..41997)
                     /locus_tag="VXB91_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0469996.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            complement(42081..42557)
                     /locus_tag="VXB91_000490"
     CDS             complement(42081..42557)
                     /locus_tag="VXB91_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEV0469997.1"
                     /translation="MDKEDLIRTLELAPHVEGGYFRQTKKASDTINLAGKGRALYTSI
                     YFLLEETNPSHFHRLTADEIWYFHAGSPLTVHMITADGHYEAVTLGLDISKGQQLHYC
                     VPKGTIWGSTVDKDYALVSCLVAPGFEFEDFELFERVDLLATYPEHKEMIERLTRY"
     gene            42564..43091
                     /locus_tag="VXB91_000491"
                     /pseudo
     CDS             42564..43091
                     /locus_tag="VXB91_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(43406..45097)
                     /locus_tag="VXB91_000492"
     CDS             complement(43406..45097)
                     /locus_tag="VXB91_000492"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HEV0469998.1"
                     /translation="MNTKELIASELSSIIDSLDQEAILKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            45233..45679
                     /gene="argR"
                     /locus_tag="VXB91_000493"
     CDS             45233..45679
                     /gene="argR"
                     /locus_tag="VXB91_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEV0469999.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDEWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            45730..48264
                     /gene="mutS"
                     /locus_tag="VXB91_000494"
     CDS             45730..48264
                     /gene="mutS"
                     /locus_tag="VXB91_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HEV0470000.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKPDSQNNFLVSIDREGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPTLAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREKSA
                     NLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLVTGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTESPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            48411..50105
                     /gene="patA"
                     /locus_tag="VXB91_000495"
     CDS             48411..50105
                     /gene="patA"
                     /locus_tag="VXB91_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatA"
                     /protein_id="HEV0470001.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLGALLAG
                     KYEAIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SDELLGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMVQSDPSVVGSIASFVNYL
                     SQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDIPDEELVGSLSFENVTF
                     TYPMDKEPMLKDVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQEGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
     gene            complement(50435..50698)
                     /locus_tag="VXB91_000496"
                     /pseudo
     CDS             complement(50435..50698)
                     /locus_tag="VXB91_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199219.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            50896..52662
                     /gene="patB"
                     /locus_tag="VXB91_000497"
     CDS             50896..52662
                     /gene="patB"
                     /locus_tag="VXB91_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HEV0470002.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAYQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTRVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMSNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPVMNGMSLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     NQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTESKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFE"
     gene            52801..53490
                     /locus_tag="VXB91_000498"
     CDS             52801..53490
                     /locus_tag="VXB91_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEV0470003.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQVGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKDLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLNEL"
     gene            53494..53673
                     /locus_tag="VXB91_000499"
     CDS             53494..53673
                     /locus_tag="VXB91_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0470004.1"
                     /translation="MEHLVVLSFIFSKFLECGILRKRLNSDKNWRNSTKKLEKNEGKR
                     YDRKEEILEEEHVTY"
     gene            53660..55009
                     /locus_tag="VXB91_000500"
     CDS             53660..55009
                     /locus_tag="VXB91_000500"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HEV0470005.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWGTFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAVVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            55133..56593
                     /locus_tag="VXB91_000501"
     CDS             55133..56593
                     /locus_tag="VXB91_000501"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HEV0470006.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGIIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVVIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDEFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENILKEISK"
     gene            56607..57038
                     /locus_tag="VXB91_000502"
     CDS             56607..57038
                     /locus_tag="VXB91_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEV0470007.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAGDGQIFTGF
                     CMEGTCGVFHLCAERATLFNMYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVAELIPYWWGEERASKFNE"
     gene            57162..57233
                     /locus_tag="VXB91_000503"
     tRNA            57162..57233
                     /locus_tag="VXB91_000503"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:57195..57197,aa:Glu,seq:ttc)
BASE COUNT        16749 a        10881 c        12459 g        17189 t
ORIGIN      
        1 ctaaagctat tcttgatgta gaacttagaa caagaaggga gattatctat gaaactattg
       61 tttagaaatc cagcttatag aattttgact ttatcacgct tcttcaatgc ttttggtgct
      121 tcgattttca acctggtctt tatcgtctat gcatcgacct tgtcacaagc atcttttgct
      181 gttgctatgg cgaatattgt catgattctt ccgaccctct ttacagtttt tgtagggatt
      241 cgggcagatt acacgaggga caaggtcaaa tggatggtct atagcggttt gtttcaggcg
      301 gttctatttt tcctagcagc cctagttgtt cagcaagcta gtctctttgc cttttctagc
      361 ctgtgtttga tcaatgtcat tagtgatgtc atcagtgatt ttgcaggtgg cttgcgcatg
      421 cctcttatta aggaaaaagt agctgaagat gatctgatgg aggcttattc tttttcacag
      481 ttcatcacct atatttcagc tattggtggt caagctttcg gagtctggct cttagctcta
      541 tcggtcaaca atttttctct cgttgcggga atcaatgcct gctttttcct agtatcagcc
      601 actatcctct ttttaggaaa aagcaaattg agcctgtcaa tgtcatctgc tgatggtgaa
      661 aacttaaaaa atgagaagct ttctatcaaa gaccagttcc taacaattta ccgaaattta
      721 cgtctcgttt ttcttaaaag tgggcagaaa aactttggtt ttatgctctt tgctgtcttg
      781 cttattaatt ccttgggtgg cgctttgggt ggaatttata atatcttctt tttgagccat
      841 tctctcttga atttttctta tacagaggca ctatttatca atcaattctg tgttttagta
      901 gcaatcatca tcagtagcct tacgggcaat gattattttg ggaagcagtc cttgcctaga
      961 ttgatgatgt gggcgaccgt aggacttagt ctagttggtt tggctaattt attcaatcaa
     1021 gtcgtgcttg gtttgctatt tctcttcttt accctgtatg tgtctggtaa agttcaacca
     1081 aagattagtg ccatgctcat gaaaaatcta gctccagagg ttctagctcg tactagtaat
     1141 tttttaggtc tattgtttac cttatccata cctgtgggaa cagcttgttt ttcactagta
     1201 gccgtatgga atatacagtt gacttggatg ctatttgttg gtctttcctt gctagctatt
     1261 tttttgacaa ttcttaatct caaaaatgat atctaaatcc taattttttt cttactgttt
     1321 taatcccttt atttgtggta aaataagact attaagttta aagaggattc cctatgaaat
     1381 tacaaaaacc aaaaggaacg caggatattt tacctgctga atctgctaag tggcagtacg
     1441 ttgagggctt tgcccgtgag attttcaagc gctataacta tgcagaagtg cgcacgccta
     1501 tttttgagca ttacgaggtt atcagtcgct ctgtcggaga tacaacggat atcgtaacca
     1561 aggaaatgta cgatttttat gacaagggtg accgtcatat taccctccgt ccagaaggaa
     1621 ctgcgcccgt tgtccgttcc tatgtggaaa ataaactctt cgccccagaa gtgcaaaagc
     1681 caagcaagtt ctactatatg ggacctatgt tccgttatga gcgtccacag gcagggcgct
     1741 tgcgccaatt ccaccagatt ggtgttgagt gttttggctc tagcaatcca gctaccgatg
     1801 tggaaacaat ctctatggca gcctattttt tgaaggaaat cggtattcaa ggtgtcaaat
     1861 tgcacctcaa cactcttgga aatcctgaga gccgtgcagc ctaccgccaa gccttgattg
     1921 actatttgac accgctcaag gagaccttgt ctaaggatag ccaacgtcgc ttggaggaaa
     1981 atcctcttcg tgtcttggac tctaaggaaa aagaagacaa ggtggcagta gagaatgcgc
     2041 cgtctatctt ggactttctt gatgaagaaa gccaaactca ttttgatgct gtgcgtcaga
     2101 tgttggaaaa tcttggagta gattacatca tcgataccaa tatggtgcgt ggtctggact
     2161 actacaacca caccattttc gagtttatca cagagattga gggcaatgac ttgacagtct
     2221 gtgcgggtgg tcgctacgat ggtttggttg cttactttgg aggccctgaa actgctggat
     2281 ttggttttgg gcttggtgta gagcgcctgc ttctcatcct tgaaaaacaa ggcgtggccc
     2341 tccctatcga aaacgcccta gatgtctata tcgcagtctt gggtgatgga gcaaatgtca
     2401 aagccctaga actagtccaa gctcttcgcc aacaaggttt caaagcagag cgtgattacc
     2461 tcaaccgtaa gctcaaagct cagttcaagt cagcagatgt ctttgcggct aagaccctca
     2521 tcaccctagg agagagcgaa gtcgaaagcg gacaagtgac ggtcaagaac aaccaaaccc
     2581 gagaagaagt gcaagtgtca cttgagacaa tcagccaaaa cttctcagaa atctttgaaa
     2641 aactaggatt ttatactcaa tgaaaatcaa agagcaaact aggaagctag ccgcaggttg
     2701 ctcaaaacat ggttttgagg ttgtagatga agctgacgtg gtttgaagag attttagaag
     2761 agtattaatg atagataaag tggtcaggaa cttactcctg acctttttcc tttgcaaaat
     2821 gacaaaaatc ataaactttt tgacaactat acttgtcaaa aagaaaaaga tgtgttacga
     2881 tgtaagcaag ttaagagaaa agaagaaagg agctatgatg tgggtactag gatttatact
     2941 atttatgatt ttcttttatt ctaataattc taaaaaaatc aagaaactag agaataaaat
     3001 caaaaaactt gagcgaaaag agaaaggaaa cgcagaaatg tcgagattat ttcaagaaat
     3061 gattggaaag gaaccaatta taacgggagt gtatattggg ccagataact gggaagttgt
     3121 ggatgttgat gaggaatggg taaagctacg acgtgtagat aatacgggaa aagaaaaatt
     3181 caagttgcaa cgcattgagg atatccaaac cgttgaattt gacggagagt aggtgtgtaa
     3241 catgcaactt aaaaatcgtc taaaagagct tagagctcgc gatggtctca atcaaaccga
     3301 cctagccaaa ctggcagggg tttccagaca gaccattagc ctactagaac gggatgagta
     3361 caccccatcc attatcattg ccctgaaaat atctcaaatt ttcaacgaaa cagtcgaatc
     3421 ggtatttcgt ttggaggagg acgagtgatg aacaagtata aagtgattta ttatgtagtg
     3481 gtcatagctt tattagtcag tgtatttcta ctgattggga tggacctaag ctggtttaat
     3541 ctctatcaaa gcgaccaatt tgtttgggtc tactttgctc tcatcccagt aattgaatgg
     3601 attgaaaaga aatccaaaaa tctagcaagt gaaaaaggag aatgaatatg aaaaagaaac
     3661 gtagattgtt atttttgatg tctattgtct tgggcatgtt tgtagggatg tttaaggcac
     3721 gtgtcgaatc ccacgaaatt attttagatg taaaagcctt gatgccatgg atatcagcta
     3781 tttgtttact gataggtttc attagtatgt ttttgacttt caatttctta aagaaaagca
     3841 gaaaatttca ttccttgtat caagaggaaa tggatgacga tctgaatgaa acctattatg
     3901 tgcaaatgta tcggaatctt gagtttggaa ccattgcttt taatattaca ggtgtagcga
     3961 ttccattggc tatttttatt tcattaagtg aggtgattat attgcataca aaccctcaaa
     4021 catttttcct ttctttctta ctctttgtgg tattcttagt cgctcaaaaa tctcttttta
     4081 aaaccattgc gattgttcgt cagtttgatt tggaattttt cgctacacca aaggatgtct
     4141 tgaactatat aaattcttat gatgaagggg agcgtcaggc taatttggaa cagagttttc
     4201 gaattttatt ccaattacac caatatgtct taccagcctt atatattttt cttattatca
     4261 tttctttctt gacaggagag attcagttac tagctttctt gcttgtagga gccatccatg
     4321 tttatatcaa tgtgatgcag ttacctatgg taaaacgtta tttcaaataa aggagttatc
     4381 tatgaaatta cttaaaaacc ttggctggat tcttctagcc cttctatcct ttttatttat
     4441 ctatggcttt attcaggggc tcgcgactgc gtcgcttgct ttaggcgctt caccctatgc
     4501 tgttactcta ctctatgtgg cctttgctgg agtatatgtg tacggcattt acaaatggta
     4561 tcagaaggct cctgttcata ttgagaagag cggctttaat cgatttattt ggcttcctgt
     4621 cttggtttgg ttcttatctc tggtcgttca attcttcttg ccagatgatc cttcagtaaa
     4681 tcagcaaata gcgacagact tgaccttgtc tcaaccactt ttctcattct ttgctgtggt
     4741 tatttttgct cctttgacgg aagagattgt ttttagaggg atgttagcac gctatctctt
     4801 tcctaagcag gacaatagta aacgaaccct gatttttctt ctggtatcta gtcttctatt
     4861 tgccttgatt cattttccag gtgatgtgca acaatttttt gtctatttta gccttggttt
     4921 tagtttgggt ttggcttaca ttagcagaaa aggtctggtc tacagtattt ctcttcacgc
     4981 tttgaataat ttagtcggct ttttgatgat tctcatgcta taatagagtc aggaggtcac
     5041 atgaaacgag taattttatt agcagtgatt caggcagtcg ttctattttt catcattgga
     5101 gcgctagctt atgccttcaa aggcgatttc ttctataact atctagcagt tgtctttgct
     5161 cctattgcag gtgtactgcg ttttgggacg gcttacataa cggaaattgt cttgcctcga
     5221 aaggcagccg aaatcgctga aaagcgtaaa gcaggcaaaa attcaaaata aaagagtccg
     5281 gtgaagttca tcggattttt gtattatact caatgaaaat caaagagcaa actaggaagc
     5341 tagccgcagg ttgctcaaaa cactgttttg aggttgtgga tgaaactgac aaagtcagct
     5401 caaaacatgg ttttgaggtt gtagatgaaa ctgacgaagt cagctcaaaa catggttttg
     5461 aggttgtaga tgaaactgac gaagtcagta accataccta cggtaaggcg acgctgacgt
     5521 ggtttgaaga gattttcgaa gagtattagc gctaattttt agggctttca cctgactttt
     5581 aaagactggc aaacttttct gatgattttc atgaagagcc tgcgctttta tggtaaaata
     5641 gtaacagaat aaaagaggag agaaataatg aaacgtagta tgtatgctgg tcgtgttcgt
     5701 gaggaacaca tcggacaaga aataaccttg aaaggatggg ttggccgtcg tcgtgacctt
     5761 ggtggtttga tctttatcga tcttcgtgac cgtgaaggaa tcatgcagtt ggttatcaac
     5821 cctgaaaaag tatctgcaga ggttatggca acagctgaaa gccttcgtag cgaatttgtt
     5881 attgaggtga ctggtcaggt cgctgcgcgt gagcaagcca atgataagtt gccaactggt
     5941 gcggttgagt taaacgtgac agctcttatt gtgcttaaca cagctaagac aacaccattt
     6001 gagattaagg atggcattga ggcaaatgac gatacacgtt tgcgttaccg ttaccttgac
     6061 cttcgtcgtc cagaaatgtt ggaaaatctt aaacttcgtg ccaaggtgac ccactctatc
     6121 cgcaactact tggatgagtt ggagtttatc gacgtggaga caccattcct ttctaagtca
     6181 acgcctgaag gggcgcgtga ttatttagtg ccgtctcgtg ttaataaggg gcatttttac
     6241 gctcttcctc aaagtccaca aatcacgaaa cagctcttga tgaatgctgg ttttgaccgt
     6301 tactaccaaa tcgttaaatg tttccgtgac gaggacttgc gtggagaccg ccagcctgaa
     6361 tttactcagg tcgacttgga aacgtccttc cttactgagc aagaaatcca agatattaca
     6421 gaaggcttga tcgcgcgcgt gatgaaggaa acaaaaggca tcgaagtaac gctaccgttc
     6481 cctcgtatga aatacgatga tgctatggct ctttacggtt ctgacaagcc agatactcgt
     6541 tttgacatgt tgcttcagga cttgacagaa gtggtcaaag gtgtagactt taaagtcttt
     6601 tcagaagcac ctgctgtaaa agcgattgtg gtcaaaggag ctgcggacaa ctattcacgt
     6661 aaagacatcg acaagatgac ggaagtagcc aaacagtatg gtgccaaagg tcttgcttgg
     6721 gtcaaggtgg ttgatggaga attaaacgga ccagttgcca agttcttgac tggtatccaa
     6781 gaagaattga caacagcgct tgctcttgaa gataaggact tggttctctt tgtggcggat
     6841 acgcttgaag tggctaatgc aacactgggt gcccttcgtg gacgtattgc taaagagctt
     6901 ggcttgattg ataatgataa gttcaacttc ctttgggtgg ttgactggcc gatgtttgaa
     6961 tggtctgaag aagaaggccg ctacatgagc gcccaccatc cattcacact tccacaggaa
     7021 gagactgctc acgaattaga aggtgatttg gctaaggttc gtgccattgc ttacgatatc
     7081 gtcttgaacg gttatgagct tggtggtggt agccttcgta tcaaccaaaa agaccttcaa
     7141 gaacgcatgt tcaaggctct tggtttctca actgaagaag ccaatgacca gtttggtttc
     7201 cttcttgaag ccatggacta tggtttccca ccacacggtg gtttggctat cgggcttgac
     7261 cgttttgtca tgttgcttgc tggagaagaa aatatccgtg aagtcattgc ctttcctaag
     7321 aacaacaagg caactgaccc aatgacacaa gctccatcaa cagtcgctct caaacaacta
     7381 gaggaactca gcttacaagt agaagaagat gaaacaaaca aaacgaatta agcggtggcg
     7441 ctattatctg cgccgctttg cttatcagat aaaaatttta cgtgtcttac aaagtatctc
     7501 tcgagaaaag tatgatgaga agatttcggc ctctctggtc tatggttttt tatcagcagt
     7561 agcagttaat ttctttttcc aaccagggca tgtgtattcg agtggtgcaa caggtctggc
     7621 acagattatc tctgccttga gtaatcactg gtttggtttt catattccga tttcgctaag
     7681 cttctacgcc attaacttcc ctttgatggt cttagcttgg tatcagattg gccataagtt
     7741 caccgtcttt acctttatca cggtatctat gagttccttc tttatccagt ttgtccctgt
     7801 ggcaaccttg acggaggatc ccattatcaa ttcccttttt gggggtgttg ttatgggttt
     7861 ggggattggt tttgctcttc gaaacaatat ctccagtggt gggacggata tcgtcagcct
     7921 gactattcgc aagaaaacgg gtaagaatgt cggtagtatt tctttcttgg taaatggaac
     7981 tatcatgctg atagcaggtt tgacctttgg ttggaaatac gctctttatt ctatgattac
     8041 catctttgtc tctagccgtg tgacagacgc agtctttact aagcaaaagc gtatgcaggc
     8101 catgattgtg acaaatcatc cagagaaggt aattgaaaaa atccataaaa aattgcaccg
     8161 cggagcaacc atgatccacg atgcagaagg aacctataat cacgagagaa aggcagtttt
     8221 aatcactgtc attacacgtg cagagtttaa tgaatttaaa cagattatga cacaagtgga
     8281 tccaagctcc tttgtctctg tctcggaaaa tgttcatatt ctaggaagat ttgttgagat
     8341 agataattag tgattaatac tcttcgaaaa tctcttcaaa ccacgtcagc ttcaccttgc
     8401 cgtatatatg ttactgactt cgtcagttct atctgcaacc tcaaaaccat gttttgagct
     8461 gacttcgtca gttctatcca caacctcaaa acagtgtttt gagcaacctg cggctagctt
     8521 cctagtttgc actttgattt tcattgagta taaaaagatc ttgggaaaag actcaatttc
     8581 agtagaaaag gaagtaaatc ttcccacaat aaaacgcata gtatcaagtt ttttcaatac
     8641 ctgatagtat gcgtttttgc ttttaacgac tctttgccca gtctcttatt tttcgataat
     8701 tttgtgggcg atcaattgac ggtaacaaat ttgtttattg tttttattat cattaataat
     8761 ctggagaata gtttcaaggg aaacacgacc aagctctaaa ctattgatat cgacataggc
     8821 tgccaagttg agcttgggat taaccgagtc aaagctgaga acagggacat ccagctggtg
     8881 tttggcaata tagttacaaa caccttcagc taggaggcta tcggttgtga tgatagcatc
     8941 aatttgtgga tcgtgcttga ataatcgctt gctaaattta tagccctttt cttccagaaa
     9001 ctcgtcggca aagtagatgc gattgttgtc agtggtaagt ttgtaatgtt taagcgcctg
     9061 ttcatagcct gttaaacggt ctttggtcac gaagagcttt ttacttcctc cgataaaggc
     9121 aatgcgtttg cagccttttt tgatgaaata ttcagtcgca tcaaaaccag cttgaacatt
     9181 gtcgttgtcg acaagtggga tgaaaggaga tagagattta cctaggataa ggaaggggaa
     9241 ctgttcttct gcgacgagtt ttacgagagg gtcttcttct tgggcataga gaaagattag
     9301 cccatctaca cgcttgccgt agaccatttg tgaaatagcg ttgagacgct ccttctcatc
     9361 tttccctgtt gctatctgaa tggcatagtg gttttcagat gcgacttgag agatgccacg
     9421 tagaaccgat ggaaagaaag gattctggta gaaggcgtct gagtcatcag gaagaactaa
     9481 tccgataacc tgagtatagc tgcttaccaa gctacgagcg ttgaggtttg ggtggtagtt
     9541 gagttccttc atagccttgc gaacgcgttt ttttgtttcg tcgctaatgg ttgatttatt
     9601 ttgaataaca cgggttacgg ttgaaggcga aacaccagca gccttggcca cgtctttaat
     9661 cgtaacgggc ataaaaatct cctatttatg gtaatttgga tcacggaaat gtgttttata
     9721 aaagatagtg accagataca gaacaaaaag aatattttgt acagtaatca gggttgtcat
     9781 attttggcca aataatccca aaataagtgt aatcagagtc ggcaatccta aacagttcaa
     9841 gataaagtga tagcactctt taaaggttct aaatgaaaag aggcgtgatt tcttagtgat
     9901 ataaaggaga agactagctc ctagagagac gataaagaaa ttcaaaccaa agaggaagct
     9961 cgcaccgaga actaggaaga ggctgatata gacacgattt tgttggtacc agtctttaga
    10021 aattgcttgg gtcaagctgt ctttgctttt gaaactctca gtctgaatgg ctcggtaaga
    10081 gatgcgggtc agttccttgc tttccttgct gatgactagc tcatttgtat cgaaatgcag
    10141 ttgcaagttc ttaggtaatt ccttgatttg acttggacca atcacaacag aagaggcttg
    10201 actaactgtt ccagtataag ttaatgtgcc atcgacaatt gtagcatgtt cagagagatc
    10261 ctggacaacc tcatttgtca gaggttcata gacattatcg ataaaagttt ctagcggata
    10321 ggtctcctgg gagctgtttt ggatagcaat gggtaccata gacaagctga taaggaagat
    10381 actggtaaag agaagttgaa accagttgag cccgaaacgt ttggacaggg gcttacgaaa
    10441 ccccaaaata cttgaaaaaa aggaaaatgg atatggaagc ataggtatct ttctaaaagg
    10501 tgttttctat ataagtatta ttatatagag aaatgcgctt tatttcaagt ctaggagaaa
    10561 aattgcttgc tacaaggata ttatttacag tgacaattgc taataatcaa tgaaaatcaa
    10621 agtgcaaact agccacaggt tgctcaaagc acaactttga ggttggagat aaagctgacg
    10681 tggtttgaag agattttcga agagtataaa atgaaaaagg gtggcgggga taaattatcc
    10741 cttgtcgcca ccacttgtaa gtcctgaaac aaagttcttt tgtaggaaga agaagagaat
    10801 acagattgga agggcgatga ggatagcacc tgctgagaag taggcaatct tcaagttttt
    10861 cgcattgtta acgaaggttt ggagacctac ggcaacagta aagtattctt tctcacgaag
    10921 caagaaacta gagaggatgt agtccccgaa aggtcccatg aaggcccaga gagcttgtac
    10981 ggcaaccatt gggcgaacaa gtggaagaac aatttgccag aagcggcgga agtgtcctgc
    11041 accgtctagt tttgcagatt cgtctaaaga cattggcact gtatcgaagt agcctttcat
    11101 gagccaagca ttcatcggga taccaccacc aacgtagagg aagatgagga accagttgtg
    11161 gttaagggcg ttcaacataa gcgccataac gaagaaggct gtcaaagcgg ccatagttgg
    11221 caccatttgg atgatcaaga agaagaccaa actttgttta cgagccaaga agttgtaacg
    11281 gctgtaagca taaccagcaa gtacgatgat acttgtttga acagccatgg taattaaggc
    11341 gataatcaaa gtgttgaggt accaagtacc gtacaaggtt tcagtgaaga ggcctttaaa
    11401 gttatcaaaa ttgaggtcga tattagtatc tagtttaaag gctgagacgt tacctgcttt
    11461 aaaggctgac ataatggtaa tcaacagtgg atagataatt acaattgata gaccaatcag
    11521 gtaaaggtaa gtaaggcttt gagtcagtct acgtttgagt ttaattgagt tattcatctt
    11581 agacgtcctc catatcaaat gcgtgtagtt tcttgaatgc gatcatagag attgagatga
    11641 caatgataga gataatcaag gtaacagctg ccgccattga gtattgagga gatgtacctg
    11701 ttgtcaaacg gtagatccat gagatcaaga tatcggttga accagctcca cctccgacac
    11761 taccaggtcc tccaccattg aagaggtaca tgatagagaa gttgttaaag ttgaaggtgt
    11821 attggctaat caaagtaggt gccgcaacag ccaaaatcat tgggaaagtg atgttgcgga
    11881 atttttgcca agcgttggca ccgtcaatat aagctgcttc gtaaaggtcg ttaggaatag
    11941 attgcaagat acccaaggtc agaacgtaga tgtatgggaa tccgagccaa ccttgcatca
    12001 taatcaaggc aatcttagtc caagttgggt ctgttttcca aggaataaga gctccatcaa
    12061 ggaaaggaag gaatttagcc aagattggca atacttgagt gttgatagca ccgacactat
    12121 cgttaaacat gtttgagaat gtcaagatag tgatgaaggc tgggacagcc caaggaagaa
    12181 ggaaaataac accaaagata cgttttcctt tgataaatgg ttggttggca atgatagctg
    12241 tgaagatacc aattacgatt tgtaaagtag aagctgccaa agcccaaatg atagtccaag
    12301 aaagaacaga accaaaggca gaacggaagg tactcaagct ccaaatgttt gtaaagttgg
    12361 tcaaaccaac ccagtccaac aacttgtttg gtggcaagtg ttggaagtcg tagttggtaa
    12421 aggcgatcat caaggttacg ataactggga agataatcgc gaaggtcatg gcaacataag
    12481 atggaatgat caagaggtaa gggaagccat tttcataaat ccctttgatc atgtctttga
    12541 gtgtgcgtgg aactggaatt ccattgttaa tgcgttttgc aatcgtatgt gcatctttga
    12601 tatttgagaa ataaaagagt acataaacga ttacaaagat tagatggaag gcaccacgaa
    12661 tcagcataaa gagggaatta tcacgacctg gtttgtcacc aagagtgatg aggttgctca
    12721 attcaggggt tgcaagtgct aggaagtaaa ggacaaatac gatggttaca ccaaggaaga
    12781 taaaaccttt ggctttttgt ttattgtaaa tctgtcctaa cccaggaatg atagacagca
    12841 gggctgcttt actaggttgt tgcttttcca tattaactcc tttcatagga tactactttt
    12901 ttataagaaa gctaaattat ttgtgtctct attgataaat tcaaaggggg atttgatttc
    12961 cacccccctt gaacaaattt tttattcacc aaatttttgt ttgattgttt ctttgatcaa
    13021 tgttacagca tcgttagcag ctgttttagc atctttttga ccacttacag catcaaagag
    13081 catatttttc gctggatccc aaactgcaga catttgagag atgtttggca gtggttgagt
    13141 gttcttgaac tgtttgataa cagctgttgt caactcatcg tttttacctt cagcgtatga
    13201 acgagcctca gtattagctg ggatttcgtt agtcttatca tataatactt tttgttgttc
    13261 agttgcaaca aggaagtcta caaatttttg agaagcttca aggttcttaa cggcttgagg
    13321 aatgacccaa gctttaccac caccgaatgc agcatattct tttccatttg gaagagttgg
    13381 gatagttgca actccgtagt ttactttagc atctttaaag gcttgagctt tccaaggtcc
    13441 gtcgatgata gcagctgttt taccttcttg gaattgagtt tggattaagt ttccagcacc
    13501 ttctgtatct tgcatacctt taggccattt ttcgtaccaa gatttagcgt agttgatacc
    13561 tacgatagaa ccgtcgtttg caagaccgat gtctttagcg tctttaccgt tttggccaaa
    13621 gacgtaagca ccgttaccgg caagaagtcc atatgtatag tagaagtttg tccagtcagc
    13681 taggaaggca gtagttttac catcttcacc agcgaatgcg tatttgctat ctttagcaag
    13741 gttttccaag tcagcaaatg tttttggagc atctttcacc aagtctttgt tgtagtacat
    13801 aacaagtgac tcgataacgg caggagcacc gtaaacttta ccattagcag ctgttacaag
    13861 agatttagtt gtgtcgtctg ttttagcacc atcgctcaat ttcacttctg aaagttgtcc
    13921 gtcagaacca aggctaccta cacggtcgta tggagccatc ataacatcag ggacattacc
    13981 agattggttg tcaagagaaa gtttatcaag acctcctaga gcatcaccag ttttaagagt
    14041 gacttttact ccagcttctt tttcataagc tttagcaacc tcttcaatat agctcttata
    14101 tccctcgtct acatatacag tgagttcttt gacttcagat gaaccagaat cagcaggctt
    14161 atcagcagtt ttgcttccgc aagctaccaa aagcaagcta gcaagtgtaa cagttccaag
    14221 caccgcagtg ctcttcataa atttagatga catagtgtat tcctcccaaa gaatagcaag
    14281 ttttattgat aaggaaacgc aaacgttttc ctttatgagc ttagtatagc acaaatagaa
    14341 aacggttgca agtatttttt gtaaaaattt taaaaaattt ttaagcttga tttgatagca
    14401 taattttgca ttttaataga agaaaagtat gaaatagata agaatacagt atttttaata
    14461 aaaatatatg gaatctgtct aaagagggaa accaggaggg gctacctccc tggttctaat
    14521 ccctatctat tttctatgga cgtttgtgct ttgttacata taaattcaag ctccctaagg
    14581 aggttttgta ctttgtagac tgtctcgtga gagtcaaacc ttaggattag atagttttaa
    14641 gttatctttg ctaaaatgag ttagtctcct taaaaataat caaaaaagtt ttttaaaaac
    14701 gcttgcaatt atgcttgaaa aggagtatac ttataagtaa cgcaaacgtt tgcgtctgca
    14761 aaatacgcaa cgttccatta ttttaacaca cgaggtgcta ttatgaaaaa acgtcaaagt
    14821 ggtgtgttga tgcacatctc ttctcttcca ggagcttacg gaatcggatc atttggtcaa
    14881 agtgcttacg acttcgttga tttcttggtc cgtacaaaac aacgttactg gcaaatcctt
    14941 ccattaggag caactagtta cggggattct ccttaccaat ctttctcagc cttcgcagga
    15001 aacactcatt ttatcgattt agatatcttg gtggagcaag gtttgttgga agcaagtgac
    15061 cttgaaggag ttgactttgg tagcgatgcg tctgaagttg actatgctaa aatctactat
    15121 gcacgtcgtc ctcttttaga aaaagcggtg aaacgtttct ttgaagtcgg agatgttaaa
    15181 gattttgaga aatttgctca agacaaccaa tcatggcttg agctctttgc tgagtatatg
    15241 gctatcaaag agtattttga caatcttgct tggactgaat ggccagatgc agatgctcgt
    15301 gctcgtaaag cttcagcact tgaaagctat cgtgagcaat tggcagacaa gttggtttac
    15361 caccgtgtga ctcaatactt cttcttccaa caatggttga aattgaaagc ttacgctaac
    15421 gacaaccaca tcgaaatcgt tggggacatg ccaatctacg tagcggaaga ttcaagtgat
    15481 atgtgggcaa atccacatct cttcaaaaca gatgtcaatg gtaaggctac ttgtatcgca
    15541 ggatgcccac cagatgagtt ttctgtaact ggtcagcttt ggggtaaccc aatctatgac
    15601 tgggaagcaa tggacaaaga cggctacaaa tggtggattg aacgcttgcg tgaaagcttc
    15661 aaaatctacg atatcgttcg tatcgaccac ttccgtggct tcgaatctta ctgggaaatc
    15721 cctgctggtt ccgatacagc agcacctggt gagtgggtga aaggtccagg ctacaagctt
    15781 tttgcagccg ttaaggaaga acttggtgag ctaaacatca tcgcagaaga ccttggcttc
    15841 atgacagatg aagtgatcga attgcgtgaa cgtactggct tcccaggaat gaagattctt
    15901 caatttgcct tcaacccaga agacgaaagc attgatagcc cacacttggc acctgctaac
    15961 tcagttatgt acacaggaac acacgataac aatacggttc ttggttggta ccgtaatgag
    16021 attgatgatg cgactcgtga gtacatggct cgttacacga accgtaaaga atacgaaaca
    16081 gtggtacacg ctatgcttcg tacagtattt tcatcagtta gctttatggc aattgcaact
    16141 atgcaagatt tactagaatt ggatgaggca gctcgtatga acttcccatc tacccttggt
    16201 ggaaactggt cttggcgtat gactgaagat caattgacac cagctgtcga ggaaggtttg
    16261 cttgacttga caacaattta tcgccgaatt aatgaaaatt tggtagattt aaagaaataa
    16321 gacaataatc aggagacaac taaacatgtt atcactacaa gaatttgtac aaaatcgtta
    16381 caataaaacc attgcagaat gtagcaatga agagctttac cttgctcttc ttaactacag
    16441 caagcttgca agcagccaaa aaccagtcaa cactggtaag aaaaaagttt actacatctc
    16501 agctgagttc ttgattggta aactcttgtc aaacaacttg attaaccttg gtctttacga
    16561 cgatgttaaa aaagaacttg cagctgcagg taaagacttg atcgaagttg aagaagttga
    16621 attggaacca tctcttggta atggtggttt gggacgtttg gctgcctgct ttatcgactc
    16681 aattgctact cttggtttga atggtgacgg tgttggtctt aactaccact ttggtctttt
    16741 ccaacaagtt cttaaaaaca accaacaaga aacaattcca aatgcatggt tgacagagca
    16801 aaactggttg gttcgctcaa gccgtagcta ccaagtacca tttgcagact ttactttgac
    16861 atcaactctt tacgatattg atgttactgg ttatgaaaca gcgactaaaa accgcttgcg
    16921 tttgtttgac ttggattcag ttgattcttc tattattaaa gatggtatca actttgacaa
    16981 gacagatatc gctcgcaact taactctctt cctttaccca gatgatagtg accgtcaagg
    17041 tgaattgctc cgtatcttcc aacaatactt catggtttca aacggtgcgc aattgatcat
    17101 cgacgaagca atcgaaaaag gaagcaactt gcatgacctt gctgactacg cagttgtcca
    17161 aatcaacgat actcacccat caatggtgat tcctgaattg attcgtcttt tgactgcacg
    17221 tggtatcgat cttgacgaag caatctcaat tgttcgtagc atgactgcct acactaacca
    17281 cacaatcctt gctgaagcgc ttgaaaaatg gcctcttgaa ttcttgcaag aagtggttcc
    17341 tcacttggta ccaatcatcg aagaattgga ccgtcgtgtg aaggcagagt acaaagatcc
    17401 agctgttcaa atcatcgatg agagcggacg tgttcacatg gctcacatgg atatccacta
    17461 cggatacagt gttaacgggg ttgcagcact ccatactgaa atcttgaaaa attctgagtt
    17521 gaaagccttc tacgaccttt acccagaaaa gttcaacaac aaaacaaacg gtatcacttt
    17581 ccgtcgttgg cttatgcatg ctaacccaag attgtctcac tacttggatg agattcttgg
    17641 agatggttgg caccatgaag cagatgagct tgaaaaactg ttgtcttatg aagacaaagc
    17701 agctgtcaaa gaaaaattgg aaagcatcaa ggctcacaac aaacgtaaat tggctcgtca
    17761 cttgaaagaa caccaaggtg tggaaatcaa tccaaattct atctttgata tccaaatcaa
    17821 acgtcttcac gagtacaaac gccaacaaat gaacgctttg tacgtgatcc acaaatacct
    17881 tgacatcaaa gctggtaaca tccctgctcg tccaatcaca atcttctttg gtggtaaagc
    17941 agctccagcc tacacaatcg ctcaagacat tatccattta atcctttgca tgtcagaagt
    18001 tattgctaac gatccagcag tagctccaca cttgcaagta gttatggttg aaaactacaa
    18061 cgttactgca gcaagtttcc ttatcccagc atgtgatatc tcagaacaaa tttcacttgc
    18121 ttctaaagaa gcttcaggta ctggtaacat gaaattcatg ttgaacggag ctttgacact
    18181 tggtactatg gacggtgcta acgtggaaat cgctgagttg gttggagaag aaaacatcta
    18241 catcttcggt gaagattcag aaactgttat cgacctttac gcaaaagcag cttacaaatc
    18301 aagcgaattc tacgctcgtg aagctatcaa accattggtt gacttcatcg ttagtgatgc
    18361 agttcttgca gctggaaaca aagagcgctt ggaacgtctt tacaatgaat tgatcaacaa
    18421 agactggttc atgactcttc ttgacttgga agactacatc aaagtcaaag agcaaatgct
    18481 tgctgactac gaagaccgtg acgcatggtt ggataaagtc atcgttaaca tttctaaagc
    18541 aggattcttc tcatctgacc gtacaatcgc tcagtataat gaagacatct ggcacttgaa
    18601 ctaatactct tcgaaaatct cttcaaacca cgtcagcttt atctgcaacc tcaaagcggt
    18661 gctttgagca acctgcggct agcttcctag tttgctcttt gattttcatt gagtataaga
    18721 tacaaattta tactaataca ttttgtaaaa aagcgagttt cgattgaaat tcgctttttt
    18781 aaatgctgtg gatttgggtc aatcttgtct aaaaataggg aaatcctaga tacagtgaag
    18841 gctttaaatg ctggttttta ctgtcttcag ccttatattt tttcgtagtt ggttacctca
    18901 tatctcttgt attcgcttac ataaagtatt ataatataat tgtaggaaag aaggtgtttt
    18961 tatgatatac acacttaaat tggtgttgtt tattaccttt cttgtaataa gcttgttacc
    19021 tgataagatt tttggaaaaa ataaaaaaat ttggaaaata gtttttgcaa tattgacggc
    19081 agtggcagca ttgtcattta tgtactaagt tattttaaga atgtagggaa ataaacccta
    19141 cattttttta gttttttctg ttttctaaat tctatttatc caagagcttc aacatttctt
    19201 gcttcttcgc ttcaagttct gcacgctttt cttcgatttc ggcatgtttt ttctcgagtt
    19261 cagaacaact tgcatcattg ctaaattctt ttcgccatca ggagataggg tgagtctaca
    19321 tgtctattac tcacccaaag cagtcctaca aagcaggaat tttctgttac ttttttggaa
    19381 atagtaacgt ttatacagct ttgacacttc gtatcaaagc gccaaacaca ctccgaggga
    19441 tttacagaaa gcagaaaagg aatgatctgg tataagatca ttccttttct ctctttttct
    19501 ttaagtaatt atatacaatg tacgacgaag tcgtcattgc aatgctgatc caccacctaa
    19561 agggaacttt aaacaacatt gataagataa agaatataaa caacgaaaat acgttatacc
    19621 caattaattt tattgtatat ctcatgatta aaagttaatc cttccgttgt taggaatggc
    19681 atcattttta tcccataatt gtgctaaata agtccccggt gataataaat tcatagcgaa
    19741 ttctaaagca acatcattta caaaccaact acctagatat ctagaaattg ctgaacgaat
    19801 agcacttttt gctgcatgtt ttccttttac tttaattaga tttgcaaggc ctgcagtagt
    19861 tcctcctaat gctaaagcta ttgcagtatc taatagagca cccatttgat taactgtaat
    19921 accttgccaa gctgctctaa atggagagta tgtaggtggg attgtataat cgccttgtaa
    19981 ttgtcggtta attacttctt tgatccattg ttgtgagacg tctggatgaa aagattggat
    20041 ttcgtttgca agtgtattga tttgttcttc tgttagagaa gtgacaggtt gaagttccat
    20101 atttgtttca atttgtgata cttgttcaga agcgtataca gctgaaacac ttggaatcgc
    20161 tgatacaatt aacacaattg acgtcaaaaa aaccgaaata aatttcatta atttgttcat
    20221 gagcttttct cctttttatt tgtatctgct tacattttat catatactgt tattatagtc
    20281 aaaaaaatat gctattatgt taaaaaaata tttttcaaaa tataaatgga cggatttatt
    20341 ttggatttta tttgttattt tgacctgcct ctatattggt aaccatgatt tgtttactct
    20401 caatcatcaa gaattctctt ttcgtggtag cgtttggggt ctggtactgg ccttatatca
    20461 cttattgttc attgataagt ttgtaatttc gaatcgaaaa taaagattag aactatgatt
    20521 gactggctac ttttaatatt gattttggag gaagattttg tctctattat ttattatttt
    20581 aaatttatct attttgtaca agatttattc tttgagacgg gagaaatcga aatacttgat
    20641 ttatacggcc tatatcatat ttggggtaaa tgtagtatat ggtattcaat ggttattaag
    20701 agaactgatt tcaactattt ccccttaatg tgtatggaaa ctataacaaa acgcataaga
    20761 ttaaggtttg tgtacctgtt cttatgcgtt tttataatat tgaagatttt cggtaagttt
    20821 tatacctttg ggaagtctag tttagaatgc tttcccaacc aaaatctctg cttcgatggt
    20881 aatctctgtc agttggctcc agtcaatctt gctctggtca acgtgaaaga ggagaggagt
    20941 catactgagt agggcttgga gttgttctgc tgtgatagtc ttagtcagag aggcagtttg
    21001 actagatagg atggtaaagt gttcctggaa atgctccttg atatcttggt tagaatactc
    21061 cttgtttgtc agctggtcct gtactctttg acggatttct ttgaggtgat tttcagttgg
    21121 gataaccttt atcaagatac cgtctttgga taaaacgcga cgaaattctc catagttggc
    21181 aggtgagaag atatcaagca gaatatccat gttagcgtct tttataggaa gtcgtgccaa
    21241 gtcgccaaca aaccaattga ctgcccagtt gggttcactt ttagcagcga tttggactga
    21301 atctttggag atgtcaaagg catagaaagt tttttcagag tgactttctt gtagtttgcg
    21361 agaatagaat ccttcaccac aaccgatatc caaaattgtt gtggtagttt ttgagcttgc
    21421 aagcaagtca gatacagcat ctaagatagc ttggtaaaag ccggcttcta ggatttgttg
    21481 acggttttga aaattttcct tgttatagtt agcagattgc ttgatttgag gtgctagatt
    21541 gacatagcca aatttcgcca agtcaaaaga atgacggttg cagcacttga aattagtctc
    21601 taacagagtc agattttctt gacagatagg acaggcaaag gcagtcgcag aagcaaaacg
    21661 ctgaagtttg ggcttgagat ttgtattcat agtttaagtg tatcaaaaga ggcaaatgaa
    21721 agcaacttta ggaataagta gatgggagat tcagtagaaa taaaactaat tctccaattt
    21781 atagaatgaa attgctttta tatctaaatt gctatataat aatgataagg aggaaataag
    21841 tatgttaaaa gaagtattaa ccgttgcaaa agttgcgaaa aaatcttcat tatttttggg
    21901 tggtgtcgca tttggtaccc ttggtttgaa aatcttagca agtaaggaag ctaaaaaagg
    21961 ttattctaaa gctttggcta aggcttacaa gttgaaagac gagctagatg catctgtttc
    22021 tgttgtgaag caacatggag acgatgtctt gcaagatgcc aaatatttgt acgagcaaga
    22081 gaaaaaagaa gagcaattag atagccttat aggtgaataa tatgtctttt aaagtgctac
    22141 atagaggata ccaacatatc cgactatcat cttctttttc acttaccttg gatattcaag
    22201 actatcttcg ttccttggcg agagatgaaa aggggattga gtctatccag ttttacatgg
    22261 atcaacagca ctttactcta cgcataaaag aaggcttttc tgtattagat aatgcagaag
    22321 cctttttaaa aagaattgat aaagggaaag tttctgagtt gatgactctt cccattcgta
    22381 gagaagagag tgcttattct attgtttcag gtgcagcggt taagcgtgta ctttttcgta
    22441 gttttgtgcc gtatcctatt cgctatatat ggacttgtta tcaggctttg ggttatatta
    22501 gagaagccta tcaaacacta gcgcgtaagg aactaacgat ggaagtcttg gactgttcgg
    22561 ctattttatt gtctttgttt atgaaccaat ccaagacagc tagcaatatc atgtttatgc
    22621 ttgatttggg gaatcattta gatcagtggt ccttgaaaaa aactgcaaca gatttagaac
    22681 agagtcttct tgcaaaagag agcgatgtat tcctagtaca gggcgatacg gttgttagta
    22741 tcaagagttc cgatgttcaa ataggagatg tcttgatctt atctcaagga aatgaaattc
    22801 tgtttgatgg acaagtagtt tcaggtttag gtatggtcaa cgaaagttcc ttgacaggag
    22861 agagttttcc agttgaaaaa agagagtctg atttggtttg tgcaaataca gtattagaaa
    22921 ctggagagtt acgcattcgt gtaacagata atcagatgaa cagccgtatt ttacagctga
    22981 ttgagttgat gaagaaatct gaagaaaaca agaaaacgaa acaacgctat ttcatcaaga
    23041 tggcggataa agtcgtcaaa tataatttct tgggggctgg gctgacttac ctattgacag
    23101 gttctttttc taaggctatt tctttcctat tggtcgattt ctcctgcgct ttgaaaatct
    23161 ctactcctgt agcttatttg acagttatca aggaagggtt gaaccgtgaa atggtgatta
    23221 aggatggaga tgttctggag aaatatctgg aagttgatac tttcttgttt gataagacag
    23281 gaacaatcac aactagttat cctatagttg aaaaggtgtt accttttgga gactatagtg
    23341 aggaagatat tctcagaatc agtgcctgtc ttgaggaaca catttatcat cctattgcta
    23401 atgccatcgt caagcaagct gagatagagg gaattgaaca tgaggaaatg catgggaaac
    23461 tccaatatat cgcaagcaag gggatcaaat ctcatataga tggccaacca gttcttattg
    23521 ggaattatgt cttgatgcag gatgagcaga ttcatatcag ttcagaacaa aatgctttaa
    23581 ttgaagagta caagagtcac tacaatctct tattcttggc ttatcaaaat gaattgattg
    23641 gaatgttctg cattcatact cctttgagaa aagaagcaaa aacagccttg gataaactta
    23701 aggcacaggg gaaaaaattg attctggcaa caggggacac cttggttagg acaaaggaat
    23761 tagtcaaaga tttgcccttt gatcaggtct atacagactt gaaacctgat gggaaatttg
    23821 agttagtaga gaaactgcag aaagcaggtc acactatttt gatggttgga gatggattga
    23881 atgactcagc ggctttaact ctatcagata tcggtgtggt gatgaatgag agtgcagata
    23941 tttctaagca gatgagtgat atcttattgt tagataatcg tttggatttc ttccaagagt
    24001 tggattcgtt atcatcatct ttgcaaacac tcatcaagaa aaatattcaa gataccgttg
    24061 tcgtaaatag tagtttgatt ggcttcggct tatttaattg gctcagtcct tcaaatctct
    24121 ctatcttaca taatctaaca accttgcgca ttgtcctgcg tagcctgtct attaaaaata
    24181 gatagatgag agttattaac agcaaaaagg agttaccttt ctcgaggtta actcctttgt
    24241 ttatagataa atgttgaata gtttagtaag tcaatacaaa gtattttttc ttcccacgac
    24301 ggataacagt cagttcattc tctaacttat cagcgtcact caagacatag tcaagctctt
    24361 ggatgcggtc gccgtttacg tagatggctc cgttttggac gtcttcacgg gcttggcgtt
    24421 ttgagttaac tataccagat gagacgagca gttccacgat attgttgttt tcgtctgcct
    24481 gtacttggta gtttggcaca ccacgaagtc cttgtttgag ctctttgaca gaaaggtttt
    24541 tgatgtttcc tgcaaagagt tgctcagtga tgttaagtgc ttctttgtag gcttcttctc
    24601 cgtgaacaag tgtaacaact tcacgagcca agactttttg agccaagcgt tcgtgtggcg
    24661 ctgcttcaaa ttgtttacga atatcttcaa tctcatcaag tgacaagaaa gtaaagattt
    24721 tcaagaagcg aacagcgtca gcgtccatca cgttcatcca gaattggtac atttcgtatg
    24781 gagaagtctt ttcgggattg agccagacgg catttccttc tgatttacca aatttcttac
    24841 cagttgcatc tgtgattagt ggaacagtga taacgtgacc agtcttgtcc gccttacgac
    24901 gaagcaattc ggtaccagct gtcatatttc cccactggtc agaaccaccg atttgaagag
    24961 tgacattatg gtcttggtta aggacgaaga agtcataccc ttgcatgatt tggtaagcga
    25021 actcagtgta agaaattcct gtttcgatcc gttttttaac agattcctta ctcatcatgt
    25081 agttgaccgt gaagtatttt ccaatatcac ggaggaagtc aatgaagctg atgctgccaa
    25141 accagtcgta gttgttgacc atgacagcct tgttttcgcc attttcaaag tcaagaaaac
    25201 gagaaagttg tccttggata gacttgaccc agccatctac tgtgtctttt gtttggagac
    25261 tacgttcagc atctttgaag gacggatctc cgatgagacc tgtagcaccg ccaacgagcg
    25321 cataaggttt gtgacctgct agttgcaagc gacgacttgt caagattgcg acaaggtggc
    25381 ctaggtgaag gctgtcagca gttggatcgt agccagtata ataagaaact tgaccttctt
    25441 ctagggcttt acgcaaagct tcttcatcag tcgtttgaaa tatcaaacca cgctctttta
    25501 gctcatcaaa aatgtgcatg tgttttttct cctttttaaa attattgttt ctacctattg
    25561 tatcacaaac ttgggcaata gcctagcaga atagggaaga aagtggctat tttattgaaa
    25621 atttcccttt tgtggtataa tagataaagt gaggaaatcc atgcaaaatc aattaaatga
    25681 attaaaacga aaaatgctgg aatttttcca gcaaaaacaa aaaaataaaa aatcagctag
    25741 acctggcaag aaaggttcaa gtaccaaaaa atctaaaacc ttagataagt cagccatttt
    25801 cccagctatt ttactgagta taaaagcctt atttaactta ctctttgtac tcggttttct
    25861 aggaggaatg ttgggagctg ggattgcttt ggggtacgga gtggccttat ttgacaaggt
    25921 tcgggtgcct cagacagaag aattggtgaa tcaggtcaag gacatctctt ctatttcaga
    25981 gattacctat tcggacggga cggtgattgc ttccatagag agtgatttgt tgcgcacttc
    26041 tatctcatct gagcaaattt cggaaaatct gaagaaggct atcattgcga cagaagatga
    26101 acactttaaa gaacataagg gtgtagtacc caaggcggtg attcgtgcga ccttggggaa
    26161 atttgtaggt ttgggttcct ctagtggggg ttcaaccttg acccagcaac taattaaaca
    26221 gcaggtggtt ggggatgcgc cgaccttggc tcgtaaggcg gcagagattg tggatgctct
    26281 tgccttggaa cgcgccatga ataaagatga gattttaacg acctatctca atgtggctcc
    26341 ctttggccga aataataagg gacagaatat tgcaggggct cggcaagcag ctgagggaat
    26401 tttcggtgta gatgccagtc agttgactgt tcctcaagca gcatttttag caggacttcc
    26461 acagagtccc attacttact ctccttatga aaatactggg gagttgaaga gtgatgaaga
    26521 cctagaaatt ggcttaagac gggctaaggc agttctttac agtatgtatc gtacaggtgc
    26581 attaagcaaa gacgagtatt ctcagtacaa ggattatgac cttaaacagg actttttacc
    26641 atcgggcacg gttacaggaa tttcacgaga ctatttatac tttacaactt tggcagaagc
    26701 tcaagaacgt atgtatgact atctagctca gagagacaat gtctccgcta aggagttgaa
    26761 aaatgaggca actcagaagt tttatcgaga tttggcagcc aaggaaattg aaaatggtgg
    26821 ttataagatt actactacca tagatcagaa aattcattct gccatgcaaa gtgcggttgc
    26881 tgattatggc tatcttttag acgatggaac aggtcgtgta gaagtaggga atgtcttgat
    26941 ggacaaccaa acaggtgcta ttctaggctt tgtaggtggt cgtaattatc aagaaaatca
    27001 aaataatcat gcctttgata ccaaacgttc gccagcttct actaccaagc ccttgctggc
    27061 ctacggtatt gctattgacc agggcttgat gggaagtgaa acgattctat ctaactatcc
    27121 aacaaacttt gctaatggca atccgattat gtatgctaat agcaagggaa caggaatgat
    27181 gaccttggga gaagctctga actattcatg gaatatccct gcttactgga cctatcgtat
    27241 gctccgtgaa aagggtgttg atgtcaaggg ttatatggaa aagatgggtt acgagattcc
    27301 tgagtacggt attgagagct tgccaatggg tggtggtatt gaagtcacag ttgcccagca
    27361 taccaatggc tatcagacct tagctaataa tggagtttat catcagaagc atgtgatttc
    27421 aaagattgaa gcagcagatg gtagagtggt gtatgagtat caggataaac cggttcaagt
    27481 ctattcaaaa gctactgcga cgattatgca gggattgcta cgagaagttc tatcctctcg
    27541 tgtgacaaca accttcaagt ctaacctgac ttctttaaat cctactctgg ctaatgcaga
    27601 ttggattggg aagactggta caaccaacca agacgaaaat atgtggctca tgctttcgac
    27661 acctagatta accctaggtg gctggattgg gcatgatgat aatcattcat tgtcacgtag
    27721 agcaggttat tctaataact ctaattacat ggctcatctg gtaaatgcga ttcagcaagc
    27781 ttccccaagc atttggggga acgagcgctt tgctttagat cctagtgtag tgaaatcgga
    27841 agtcttgaaa tcaacaggtc aaaaaccagg gaaggtttct gttgaaggaa aagaggtaga
    27901 agtcacaggt tcgactgtta ccagctattg ggctaataag tcaggagcgc cagcgacaag
    27961 ttatcgcttt gctattggcg gaagtgatgc ggattatcag aatgcttggt ctagtattgt
    28021 ggggagtcta ccaactccat ccagctccag cagttcaagt agtagttcta gcgatagcag
    28081 taactcaagt actacacgac cttcttcttc aagggcgaga cgataattct ctaaatgaag
    28141 tggccaatca atggattgcc acttttttct tttcgtgtta caataagggt atgaatcagt
    28201 atcagaaaaa gattgttaac ggaaaaattt attcgctcct atccggctta atatggggaa
    28261 tctgtggaat tttaggagag tacttcttta ctcattatca ggtgtcttcg ggctggatta
    28321 cctctatgcg tttgacactg gcagggagtc ttgtactcat ttggtctgca atacaattaa
    28381 aatcgcaagt gctagatatt tggcgagaca agaaaaatta cctgcccttt ttagcctatg
    28441 ctattttggg gattttttca gttcagtatt ttttctatct ctgtgtagaa tactcaaatg
    28501 ctacgacagc aactatttta cagtttatta gccctgtctt tatcctcttt tacaatcgct
    28561 tggtttatca aaaacgagcg tcaaaaagcg ctgttttcta tgttttggtt gccatgctgg
    28621 gtgtttgctt gatggcgaca aagggagacc tctctcagtt atccatgacg ccgctagctc
    28681 ttataacagg tttgctgagt gccatgggtg ttatgtttaa tgttatcttg ccccaacctt
    28741 ttgctaagcg ttatggtttt gttcctacgg ttgggtgggg gatgattttg gcaggtttgt
    28801 ttagcaatgt cctctcgccg gtttatcagc tttcctttac tcttgatatt tggagtatct
    28861 tgatttgcct cattatcgct ttctttggaa cggcttttgc ttttttcatt tccatgaagg
    28921 ctgtgtcctt ggtttctcct ttggtggttg ccgttatcag tgccagtgaa cctctctctt
    28981 ctgctctctt gagtgttttg ttcttaggat tagtagtgga ttggtccctc cttctagcta
    29041 tagccttgat tattttaccc atgatatttt tgtctataga agaagcgaaa gaaagtagat
    29101 aaaaagtctt ttcttaattc taaaagtgtg ctatactaga atagtcaata aaacacgggg
    29161 agatagttgt gaagagtgtt tttaggttgt atcggtaggg gcttgctttt accgacagca
    29221 cgttttatct cacatcccta aaaaatcata cctaaaaaca gacaaaaagg tttcaaattt
    29281 gaggcctttt ttggtagaat aggtatcatt ataacgaacc aggaggcacc tatgactgct
    29341 acaaaaatga acgctcaaga aattatccaa tttatcgcca atgctgaaaa gaaaaccagt
    29401 gtcaaagtaa cctttgaggg gcaactcgca actgctgtgc ctagctctgt tgtcaaacta
    29461 ggaaatgtcc tattcggaga ctggaaggac gtggctccgc ttcttgaagg tttggtagaa
    29521 aatcaagatt atgttgtcga gcaagatgct cgtaattctg cagttccttt gctagataag
    29581 cgtgctatca acgctcgtat cgagccaggt gctattatcc gtgaccaggt ggaaattggt
    29641 gacaatgctg ttatcatgat gggagctgtt atcaatatcg gtgctgaaat cggtgctgga
    29701 accatgattg acatgggtgc catccttggt ggccgtgcca tcgttggaaa aaatagccac
    29761 gttggtgcag gtgcagtttt ggcaggtgtg attgagccag ctagtgctga accagtccgt
    29821 gtcggagaca atgttctcat cggggctaat gcagtggtta tcgaaggagt ccaaatcggt
    29881 agtggttcag ttgtcgcagc aggagctatt gttacccaag atgtcccaga aaacgtggta
    29941 gtagcaggtg ttccagctcg tattatcaaa gaaattgatg cccaaactca acaaaaaaca
    30001 gcgctagagg atgcgcttcg taccttgtaa ttgtaaaagt aaaaaagagg cggaaccctt
    30061 tttccagcct ctttctgcta tatcggagga cagatagatg ttagatttga ttcagactag
    30121 acgagattta caccagattc cagagattgg cttggaggag ttcaagactc aggcttattt
    30181 gctggatgtg attgagaaat tgactacggg caaggatttt gttcaaattc gtacttggcg
    30241 gacagggatt ttggtctacc tgcagggaag tcagccggag cgaaccattg gttggcggac
    30301 agatattgat ggcctgccta tcgtcgaaca aacaggtcta ccttttgctt ctcaacacca
    30361 aggtcgcatg catgcctgtg gccatgattt tcatatgacc attgccttag gctgtcttga
    30421 gcgcgccctt gaggagcaac ccaagaataa tctgctcttt ctatttcagc ctgctgaaga
    30481 aaatgaagct ggtggtatgc tcatgtatga ggacgatgct tttggagatt ggttgccaga
    30541 tcaattttat ggcctccatg tccgtccaga tttgaaagtc ggccagattg cgactaatac
    30601 tcatacactc tttgcaggaa cttgcgaggt gaagatccgt ttcaaaggca aaggtggcca
    30661 cgcagctttt cctcatgaag ccaatgacgc cttggtggcg gctagttact ttgtgaccca
    30721 agtgcagtca gttgttagcc gcaatgtcaa cccaatcgag ggagcagtgg tgaccttcgg
    30781 cgtttttcaa gctggaacca ccaacaatgt catcacagac acagcttttt tacatggaac
    30841 tattcgtgcc ttgacacagg acatgagtct cttggtgcaa aagagggtaa aaacagttgc
    30901 agaaggggtt gcagctgcct ttgatatgga agtcgaagtg gaactcaaac aaggtggata
    30961 cctacctgtt gagaacaatc cagccttggc gcgtgaactg atggacttct ttgacgaaaa
    31021 agacggaatc gagttgattg atatcgaacc tgctatgaca ggcgaggact ttggttatct
    31081 cctttcaaag gttgatggcg tgatgttttg gctaggtatc gatagtccct acgctcttca
    31141 tcaccctcaa atgagtccta aggaagaagt cttagctatt ggggtggctg cggtgtctag
    31201 tttcctgaaa aagaaggcag cagaatagag ggcttgtcta tgaaatcgga attacgcaag
    31261 caagtcttgc atgaaatgaa ggctatatct caagagcaaa aacaggctat agaccaagct
    31321 ttaaccgagc gaattttaca acaccccttt tatcaagaag ccaaggtcat cgcaacctac
    31381 ctctcttttt ctcatgagtt tcaaacgcgg gaactgattg agcaggcgct gaaggacggc
    31441 aagaaggttt taatacccaa aacttatccc aaggggcgca tggactttgt agtctatgat
    31501 ccgcagcagt tggtaaaaac tgcctttgcc ttactggagc cacagggaga tttggaagtg
    31561 gtggatgcat ctcagattga tttgattcat gttcctggcc tggcttttac gacggatgga
    31621 tatcggattg gatatggtgg aggttattat gaccgctatc tggaacattt ttctggtcat
    31681 actttgagta cggttcatcc ttgtcaaatt caggacttta tacctgaaaa ccatgatatt
    31741 cctgttcagg aggtattaat tgatgaagga aatctttgat agacgttacc ctgtgacgag
    31801 tttcttcctc ttagtgacgg ccttggtatt tttactaatg ttggtcactg caggcggaaa
    31861 ctttgacagg gcagatacat tatttcgatt tggagccatg tatgggccag ctattcgcct
    31921 ctttcccgag caggtttggc gtctcttgtc tgccattttt gttcatattg ggtgggaaca
    31981 tttcattgtt aatatgcttt cactttatta tcttggaagg caggtagagg agattttcgg
    32041 ttctaagcag tttttctttc tctatctttt atcaggaatg atgggcaatc tctttgtttt
    32101 tgtatttagt cctaaatcct tagcagcagg cgcctctacc tctctttatg ggctatttgc
    32161 cgcgattatt gttcttcgct atgcaactcg caatccttat atccaacagc tagggcaatc
    32221 ctatctgaca ctttttgtgg ttaacattat tggaagtgtt ctgattccag gaatcagcct
    32281 agcaggccat atcggtggtg cagttggtgg cgcatttcta gcagttatct ttccagttag
    32341 aggagaaaaa cggatgtata acaccagcca gagattagga gcggtagtct tgttcgtagg
    32401 actcgccatt ttgcttttct acaagggaat gggaatgtga cgaagttgaa agaaaatttg
    32461 tgtaatgaaa aaagataagg cattttttga accttatctt tttattttat tttattcctt
    32521 ctcagtcaat tcttttccaa gttggatgag gtaattcttc aaatcatctt tgacttgtgg
    32581 gtgtttgagg gcgtagtcga tggatgtttt catgaagcca aacttgtctc cgacatcgta
    32641 acgagcccca ttgaactcac gagcaaatac acgttgtgtt ttattgaggg tgtcgattgc
    32701 atctgtcagc tgaatttcat ttcctgcacc tggagcttgg ttttcgagga tttggaaaat
    32761 ttcaggcgtg aggaggtagc gtccgataat agcaaggtcg ctaggagcgt cctctggagc
    32821 tggtttttca acaaaggttt caacactgta aagaccatct tttccttcgc cttgcggagc
    32881 aataaccccg taagcagata cttcgtcatg agggactggc atgacagcga tagtagacgc
    32941 gtgggtacgc tcgtagtcat ccatgagttg tttggtaagt ggaacagcct tttcgtctgt
    33001 gatatccatc aagtcatcac caagcataac gacaaaaggt tcatttccga cgaaagcctt
    33061 ggcttgcaaa acagcatctc cgagaccgcg tggatgagtt tggcggataa aatgcagccg
    33121 catgtcagtt gttttatcaa ctagcttcaa aagatctgtt ttcccttttt ctttgaggtt
    33181 atattccaat tcgaagtttg aatcgaagtg gtcctcaata gaacgttttg atttaccagt
    33241 gacaactaga atatcttcaa tacctgattt gagagcctct tccacgataa actggatagt
    33301 tggtttgtct acgattggca acatttcttt ggcaagggcc ttggttgctg gtaaaaatcg
    33361 agttcctagt ccagcagcag ggataactgc ctttctaact tttgatgtca taaaaatcct
    33421 ttctatagag ggttaagacc actcattttc tgctttaaat tcattgttca tgatgtcata
    33481 aatggcatct ttgatattgg ttccgtgata aataacttgg taaatagcct gtgtaatggg
    33541 catatagact ccaagttctt gggctagttc ataggctgct cgagtcgttg aaattccttc
    33601 gattaccatg cccatattag cttctatatc agctagggat tctcctcgtc cgagagcatc
    33661 tccagctctc cagttacgag agtggatgga agttcccgtt acgatcaaat ctcccacacc
    33721 agataagccg ctataggtca atggactggc cccgagtgct acccctaggc gggtgatttc
    33781 tgctaaacct cgagcgatga tggctgcctt agcattatca ccaaatccaa gaccatgtaa
    33841 agctccagca ccgacagcaa taatattttt aagagcacca gcagtttcaa ccccgataac
    33901 atccgtattg gtataaagtc ggaagtagtg attactaaat agctcctgaa cgtattgagc
    33961 tgtttgtaaa tctttagaag cagcagttat taaagttagg tcacgcacaa tggtctcttc
    34021 tgcatgacta ggccctgaaa caacgacgat atcactacgg agatgttcag gaatttcttc
    34081 ttcaagaatg gttgataatc gtttatggct atcaggttct aatccctttg atgcgtgcat
    34141 gatgataacc ttatggtcca aggtttgtgc aacttgctgg gcaacaagtc gtgtcacttt
    34201 tgttgggaca acaaacaaaa tcgcatccac atttttcaat gtttctgcta agtcggtgta
    34261 ggcaatgata ttttcgtcta gaacgacatc tttaaagtag tgcttattag tatggtgtgt
    34321 attaatttca ttgatttgct cgggaagatt tccccaaata cgtacctcgt gtccattgtc
    34381 atttaagact tgtgaaaggg cggttcccca agaaccaggc cccaagacgg cgacggtttg
    34441 tttttccatg atttcctcct tgatagattt ctttctctta ttctatcata ttctagggga
    34501 ttttgcactt gcattactgg ggtatggtgg aaaaatacac aaagaccgag atgaagggat
    34561 aaactcttag tctttagtta aagtgagaag aaatctgata gatagtttga ttcagtatat
    34621 gcttataata gaggtaaaca actcaggaag ttcttgtagg ttgcgagagt ttggcgaaaa
    34681 aattaaaaga ttacgtttgg ctaaaaaaat cagtcgttca gaattttgtg gtgatgagtc
    34741 tgaattaagt atccgtcaat taattagaat tgaaaatgga gaatccagac caacactaac
    34801 aaagttaaaa tatattgctg aacgtttgga ggttgaagat tacaagttga tgccaagtta
    34861 tatagagttg gataaggaat acctagaatt gaagtatttc ttgatgagga ctcctacata
    34921 cgaagatgaa actatcgccc aaaagaaaga gagtgttttt gataagattt ttgaagagta
    34981 ttatgatagg ctacctgagg aagaaagatt tatcatccca aattattcat atctagcact
    35041 agcgaactac acagttcaaa aattaccaga aaagctagtt gaaatactgt ccttctggtg
    35101 attttgctta atttctgatg ttcgagacat gattgaggag atttgtcttg attttttcct
    35161 aaaaaagggc agactcctcc cttggtttga tgctcgattt ttaaaataag gtgacttatt
    35221 ctgttaggca gttttcccct gccctctagc tctatatgga acagggagta tcagatttat
    35281 ctggcagatt gtatcaaata aggcttgaaa ctgttttgaa taggcgtata gacttgagaa
    35341 tttgagaata tgtcgtctag cagtagagac atattttccg gcaatatgaa ggaagagacg
    35401 tcgaaaacgc ttgatagtca aggcctttac ttcatcacca gctagctgct ttaaaaagag
    35461 gtagagatta taagccagac agcccatcat catacgtact tcattcttaa tcatggtcga
    35521 actatctgtc ttatccccaa agaatcctgc tttcctttct ttgataaagt tttcagcatt
    35581 ccctcgttca cgatagaatt gaaacagctc ctcactatct acactgctta aattggtcaa
    35641 atgaactttt ttacaaccat aaaaaagagc acttaatcgt actcttctct tttaaggatt
    35701 agttgaatta attcaaatcc actagttctc ctgtttctag gtagactagg cgttcacaaa
    35761 tgttagcaat gtaatcagcg aagcgttcca gatgccctat gatataaagg tattgagttc
    35821 cattgggaat tgaggtttct tggtctttca taagtccaat gatttccttt gataaggcat
    35881 aataatattg gtcaatctgt tcatcttttt gagcaatact aatagctttt gaggcttggt
    35941 gcaaaggaaa ggcaaccaat aaatcggcta gcatgctgaa ggataattta cccatttggt
    36001 gtaactgttc ttcgtcaggg gctagttgat tttcttttag ttgcaaaaca gctttggcaa
    36061 tgcctgccat atggtctccc atacgttcaa ggtctgaaca agaagacatg atgctaatca
    36121 caaatcgaag gtcagacact tgtggctgct gcaaggccaa caaacgggca caggtcaatt
    36181 cgatagcgct ttgaccttgg tttatagcat gatccttatt gataattagc tctgccatct
    36241 ccttgtcttt ggaggctaag gccagtaagg cttttgaagc tgtttcaagg acaagttgcc
    36301 ctagtcctaa aaaggattgt tctaattcat gcaattctaa gtcaaattga tttctcatag
    36361 gtttttcctt ccttatccga accgtcctga aatatagtct tctgtgcgct gatcttttgg
    36421 attggtaaac acgtcaacgg tatctccaaa ttcgcaaatt tctcctgtta agaaaaaagc
    36481 agttttatct gaaatacgtg aagcttgttg catgttatgg gtaacaatga taatcgtata
    36541 atcctttttt agttgctgaa tgaggtcttc aatttttaaa gtggagatag ggtctaaggc
    36601 tgaagtcggc tcatccatta acagaatatc aggttctact gctaaagctc gcgcaatgca
    36661 aaggcgttgc tgctgaccgc cagataagga catggcactc tttttaagat catctttgac
    36721 ttcttcccaa atggctgccc cttttaaaga tttctccact aaggcatcta attgtttttt
    36781 gtctcgaata ccatgtgtcc ttgggccata agccacgtta tcatagatag acatggcaaa
    36841 gggattaggc tgttgaaaaa ccatccctac acgcttacgt agctgattaa ggttgaattt
    36901 gctactataa atatcttgct catctaagag gacttggcct tcaatatggc aagaaggaac
    36961 caaatcgttc atccggttaa gggtttttag aaaagttgat ttgccacaac cagatgggcc
    37021 tatcaaggca gtaatctgtc tttctggtaa ttgaatcgaa atatttttta aggcttgaaa
    37081 atccccgtaa aataagtcta ggtgtctgac tgaaaatgtt cccatactag gaagctcctt
    37141 tcacaagttt tcgagataat aagcttgata gagtatttat cattaaaaca gtaataatca
    37201 aaatcacacc ggtagcatag gcttcattga catgtagccc ctcacttgac agcatataca
    37261 tatgcagggc tagagaacga cctgaagaca tgagactact tggcgtattg gtagaggtac
    37321 ctaatgtata catgagggca gctgtctcac caacgatacg gccaatagct agtatcactc
    37381 cagctaaaat acctggcatg gcaactggta gaacaattct aaaaacagtc cgtaacttac
    37441 ctgccccaag tccataactt gcttgacgca tgctatcact aacagataaa agggcttctt
    37501 ctgttgagcg aataatgact ggcaacacca tgatgactga ggttaagatt cctgataaca
    37561 gagagtattg aaaacctaag aagactacaa agaagagcat gccaaacaga ccaaaaacaa
    37621 tggaaggaat cccagacaag gtatctgagg ccaatcgcat gattttaaca caaagggaat
    37681 ctttttttgt atattccaca agataaaaac cagcaaaaat ccctatgggc aaggctaaaa
    37741 gaagagcacc aaagaccaga ataacggtgg aaataatcgc tggcataagg gaaatgttct
    37801 cagaagtata agtccaagaa aagagggata gacttagatg aggtaaacct ttgatgagga
    37861 taaaaccaat gattaaaaag agagagccaa aggttaaagc tgaaaaacaa taaacgagaa
    37921 gttttagcag gtatttactc ataagatgat tttcctttca agtaggcaaa gtaggcatta
    37981 atcaagagaa taaggaaaaa gagaactgct gaggttgcaa taagggcttc cctatgctga
    38041 cctgatgcgt aagccatttc cagaacaata ttggttgtta aggttctggt tcctgaaaag
    38101 agtccacttg gaataatcgg ctggttgcct gccaccaaaa taactgccat ggtttcacct
    38161 actgcgcgac cgatgcctaa aataactgct gataaaatac cagatctcgc agctggcaag
    38221 atgacactaa aaatactccg ttcatgacta gctcctagag ccaagctacc agaataatac
    38281 gttttgggaa ctgttcggat agcagattct gacaaactga taatggttgg caaaatcatt
    38341 attcctaata gtaacgaagc ggttaggaca ctcatgccat ttcctaaaaa gcttctaatc
    38401 caaggcacca ataattgtag gccgaaaaaa ccataaacaa tagatggaat ggccgccatc
    38461 aagttgatag ctgattttaa gaagccatag acgggctttg gacaataata aaccataaac
    38521 accgatgtca agatgcctgt tggcacccca atcacaatcg ctcctaaggt aattaataag
    38581 gaaccaacga tcattggtaa aataccatag cttgccggaa tgttcgttgg cgaccaatca
    38641 ctgcctaata aaaaacgggc aaagccgtag ttagccatga aaggtaagcc attactaaaa
    38701 ataaagaaac agattagcaa aatagctaca acagctactg ttgcactcat gaaaaaaatt
    38761 gccctaaaaa ctgcttcttt gaaggcttgt tttatcacat cttgtccttt ctagtgaaga
    38821 aagtaaggga gatacgacac ctccctactt gccttcttta tcttattgta cgatgaaacg
    38881 tctgcatctc tttagagatt tatggagcaa acattttatt taatcttgtc ccaggtggtt
    38941 aatttgccac taaaaacgtc tgcaagttca gccatactga cttggcttgc cttattgtca
    39001 ttattgacca caacagcaat accgtctaaa gcaatagcat catgggtgag actcttacct
    39061 tcttcaggag ttaattccct agaaaccata ccaatatcag cggttttctc cttaacagcg
    39121 gtaatacctg ctgaagaccc attagaggta atatcaatcg taacttctgg attttctttt
    39181 ttataagctt ctgctaattt ttccattaaa gaagatactg aagtggaacc tacaacagac
    39241 aacttgcctg ataagtgttg gcttgtatat tctgtggttt cagttttagc ttcaataaat
    39301 ttattatctg tgaccacttg ttgaccttgt ttggagtgga taaagctgat aaaatcttga
    39361 cctagcttgg aaagattaga agaccaaaca atgttgaagg gacgttgaag agggtattca
    39421 ccatctaaaa ctgtgtctcg actagccttg acaccatcaa tctctaaagc cttgacagat
    39481 ttcgttaaag atcccaagga gatgtagccg atagcattag cattcccttg aactgctgag
    39541 agaacacctt ctgtactatt ttgaatcaca gctgttttgg cagtgttgtc aattttttta
    39601 tcaccgtctt ttttgagaat ccctgtgatt tctgtgaagg caccccgtgt tccagagcca
    39661 ttttctcgtg aaatcacctc aatcgttcct gaagctgact gtttggaagc agctgactga
    39721 ttgccacagg caacaagccc aaatcctgat aagccaatgg ctgcaagagt aagcattttt
    39781 ttgaatttca taataatcac ctttatctct atgtattttt cttgtgtagg cttactacat
    39841 ttatagtcta acaagtcttt gtaaaggttt atccctgatt catgtaaaga ttgtgtaaag
    39901 aatcaaaaaa agccactttt gaaaaatggc tgctcctaaa aatagcttta aaaattatta
    39961 gtcctgtgcg aaagattggt taggaagaaa aatcgtgaag caactgcctc tgccaagctg
    40021 actcgtcacc gtgacttggc cacctaataa ttgactgagt tctttgacaa tggcaaggcc
    40081 aagaccagtg ccaccagttt gtctgcttcg acctttatta actcggtaaa aacgttcaaa
    40141 aatacgatcc tgctctaatt gactaatacc aatccctgta tctgatacag aaatcttaat
    40201 gccttcgttc accttttggg tcttgacctc aatttttccc ccttgttcag tgtaacggat
    40261 ggcattggat aaaagattga gtaagatttg ggaaagtaat tgactatctg atacgagggt
    40321 gacatcatct ggcacctgca cctttagctg taaatccttc ttcttgagct gaggttgcaa
    40381 gctttgagtc aaatcctgta caaattcagc caaagaaagg gtcgtccatt gtataggcat
    40441 ttgttgagcc ttagataagg taagaagatg ctcaacaata tgctcaagac gcaaactttc
    40501 tttgtaaata atgtctagaa agtcatcctt gagcgcttct tcttcagctg acatcccctt
    40561 aatggtttca gcaaagccct taattgaagt aactggtgtc ctcaattcat gggaggcatt
    40621 tgagacaaag gctaaattta acttttcata agttctaatc gttgttaaat catatagcaa
    40681 gacgagcaca gcttccacag attgggtggg gctaaaaacg ggaactgctg tcacttctaa
    40741 aatcaagtca ccctcatgaa acccacttac ttcttgtttt aaccttgttt tttgatcaaa
    40801 ggcttggtga actaaattcc gaatatccat ccgtttgagg tcatcaagtg aacttatgtc
    40861 gccgtccaca tcgggaaaat aatgaggcag agagcgactg gataataaca tctgaccttg
    40921 agcggaaact aaaaacgtcc ccatggttag gtgcgacaga agaacctcca ttgtttcggc
    40981 taggtccttg tattgctgat cctgttggga gactttggtt tttaggccag acacatactg
    41041 agccaaagac tttaagtctt cttgcccttt ttctaaaaag tattcactac tggtcaagag
    41101 aggttggtgc aaggtctcaa aagcaacttc ccatttccaa aggcaaaaga gccagtagcc
    41161 accttgtccc aaagaaaggg ctagaagaaa gagaccgatg cctttactga tccaagttaa
    41221 tgccatccct gcaatcagaa tgaggctaac acttagattg actagccaaa attgaaggta
    41281 gcgtttcatc tataactcct tgaacttata accataaccc cgaatggttc gaataaattg
    41341 aggggcttta ggattgtctt caattttttc cctcaactta ccaatatgaa cgtccaccaa
    41401 acgtgtttcc tgcccaaagt cataccccca gatacgttcc aaaagacgct ctctagtcag
    41461 tgtcatgttg ggatgtttca taagatagag caagagttca aattcttttg gggtcaaact
    41521 cagtaactta ttcgccttgt agacttcatg acgctcaggg tatactttca aggtcccaaa
    41581 tagccaagaa tcgtcagcga tattatctga atcatctcct tcttgttctc ctttagttcg
    41641 cctgaggaca gccttgacac gcgccagcaa ttctctaggg ctaaaaggct tggtcaggta
    41701 gtcatcagcc cctaattcca aggccaaaac cttatcaaat tcatcacttt tcgcagaaac
    41761 catcataatt ggagttttga cgcctttggc tctcagccgc ttacaaactt ccatgccatc
    41821 taattgtggt aacatgatat caagcaagat aaaatcaaag ggttctgttt ctgccaaagc
    41881 taaggccttc cgtccatttg ttaccaattg agtagaaaag ccttccttac ttaaatggta
    41941 gtcaagcaat ttcagaatgt gttcttcatc atccactaat aagacttgtt ttgtcatcta
    42001 ttatctccta ttggtaacat tataacacaa ttatcagaaa tcctaacatt gctaaatcag
    42061 attaaatttg cttatcaaga ctagtatctg gtcaaacgct caatcatctc cttgtgctct
    42121 ggataggtcg ccagtagatc taccctttca aataattcaa aatcctcaaa ttcaaaacca
    42181 ggagcaacaa gacaagaaac cagagcataa tccttatcaa ctgttgatcc ccaaatagtg
    42241 cccttaggaa cacagtagtg aagttgttgc cctttggata tgtccaggcc taaagtgact
    42301 gcttcgtagt gaccatctgc tgtaatcatg tgaacagtaa gtggggatcc tgcatgaaaa
    42361 taccagattt catctgctgt caatcggtga aaatgtgaag gattcgtttc ttctaataag
    42421 aaataaatac tggtataaag cgcccttccc ttaccagcaa ggtttatagt gtctgaagct
    42481 ttttttgttt gtctaaaata gccaccttca acatggggag ctaactctag agttcttatc
    42541 aagtcttctt tatccatcgg ggccaatggg ttgaagtaac tcttgttcaa agtggtttta
    42601 cgatttcaag aactcctctc agttctgagg acacggtaat gattgatgcg acggaagtac
    42661 aaatcaatcg ccctaaaaaa agaattagcg aatgattctg gtaaaaagaa atttcacgct
    42721 atgaaggctc aagcgattgt cacaagtcaa gggagaattg tttctattgc catgatatga
    42781 agttgttcaa aatgagttgc agaaatatcg gacaagctgg taaaatcttg gctgacagtg
    42841 attatcaagg gctcatgaag atatatcctc aagcacaaac tccacgtaaa tccagcaaac
    42901 tcaagccgct aacagctgaa gataaagcct ataaccatgc gctatctaag gaaagaagca
    42961 aggttgagaa catctttgcc aaagtaaaaa cgtttaaaat attttcaaca acctatcgaa
    43021 atcatcgtaa acgcttcgga ttacgaatga atttgattgc tggtattatc aatcatgaac
    43081 taggattcta gttttgcagg aagtctatta tttggttagg tgaattagtg aagtgtttag
    43141 gcaagtgtct ctggttacga cgtcatggcc tctaaatcga ttatatttag gggtcatgac
    43201 tagtgaagca gttagctagt tcgcatataa gcggctagcg tctaacaatt aggaacttta
    43261 gttccaataa ctttaagatt acgacgtttt aggacataaa tcgatcatat ttatgtccta
    43321 aaactagtga agcgcctagc caaagtccga ataggatttg gcgttagtta cttagattgc
    43381 tttgcaatca agtaactttg gcgatttaca tcttctctgg cgcttctact ccaagcaagc
    43441 gaagggcttc tttgagaacg actgcggttg cgtagctgag ggctagacgg ctgtcgcgtt
    43501 ctgggctttc atccaagata cgtgtatgtg catagtattt gttaaaggat tgagccaggc
    43561 taattgcaaa tttagcaatg atagaaggtt caaagttatc tgccgcacgg ttgataatac
    43621 gtgggaagtc ttgaatgagt ttaatgattt cccagctttc agtatcattc aagctatagt
    43681 tgccagctgt ttctggtttg aaatcggctt tgcgtaagat agattggata cgagcgtagg
    43741 catattgaac gtaaggtcca gtttcaccct cgaaggatac catagcttct aggtcgaagt
    43801 cgtatccatt tgtacggtca gttttgaggt catagaattt aatggctcca accccaacag
    43861 catgtgctac ttggtctttg ttttctagtt caggattttt agcctcgatt tggaccttgg
    43921 cacggctaac agcctctgca acagtaggct ctagcaagat gacattccct ttacgagtag
    43981 agagcttctt cccttctttt gtaaccagac caaaaggaac gtgggtaatg tcgtcactcc
    44041 aatcgtagcc catctcttgc aagacagctt tgagttgttt aaagtgggca gattgctctt
    44101 gaccaacgac gtagatagat ttagcaaatt ggtattcatt tttacggtag agggctgcag
    44161 ccaagtcacg tgtgatatag agagttgcac catcagactt cttgatgagg gctggatgtt
    44221 caattccata tttctcaaga ttcacaactt gggcaccttc tgattcaaga agtagtcctt
    44281 tttcagaaag aatgtctaca actgcatcca tcttatcatt gtagaaggct tctccgttat
    44341 agctgtcaaa ttcaaccttc aattcattgt aaaggcggtt aaattccact aaactttcat
    44401 cgcggaacca ttgccaaaga gcgagagctt cctcatctcc attttcaagt ttacggaacc
    44461 attcgcgcgc ttcttcatcc aagctagggt cattttcagc ttcagcgttg atgcggacat
    44521 agagtttaag gagttcatcg attggatgag cttttacagc ttcttcgtcg ccccattttt
    44581 tgtaggcaac aatcaacatc ccaaattgtt taccccagtc tcccaaatgg ttgaccttga
    44641 ccgtttgata accgattttt tggaaaatat gtgacaagct atctccgata acagttgaac
    44701 gcaggtggcc aatagaaaat ggtttagcga tattcggact agacatgtcg ataacaacat
    44761 tttcttgttt gccaatattt tggtcagcat agtgttcttt ttcagtggta acagcttgca
    44821 atacttgagc agaaatggca gatttatcaa ggaaaaagtt aacgtaaggt cctgttgcga
    44881 caactttttc aaaggcttgg ctgttcattt tttcagccag ttcagccgca atcatttgtg
    44941 gtgctttacg ttcgactttg gcaagagaaa aagcagggaa agcaatgtct cccatttctg
    45001 agtttttagg ggtttccagt aactttaaaa tagcctcttg gtccaggcta tcaatgatgc
    45061 tagataattc gctagcaatc aattcttttg tattcattaa gagctccttt ttggactttt
    45121 ctactatttt atcacaattt taaagaaaga agaaaaaatt tttgaaatct cctgtttttt
    45181 tggtataata tggttataaa tatagttata aatatgcacg caagaggatt ttatgagaaa
    45241 aagagatcgt catcagttaa taaaaaaaat gattactgag gagaaattaa gtacacaaaa
    45301 agaaattcaa gatcggttgg aggcgcacaa tgtttgtgtg acgcagacaa ccttgtctcg
    45361 tgatttgcgc gaaatcggct tgaccaaggt caagaaaaat gatatggtgt attatgtact
    45421 agtaaatgag acagaaaaga ttgatttggt ggaatttttg tctcatcatt tagaaggtgt
    45481 tgcaagagca gagtttacct tggtgcttca taccaaattg ggagaagcct ctgttttggc
    45541 aaatattgta gatgtaaaca aggatgaatg gattttagga acagttgctg gtgccaatac
    45601 cttattggtt atttgtcgag atcagcacgt tgccaaactc atggaagatc gtttgctaga
    45661 tttgatgaaa gataagtaag gtcttgggag ttgctctcaa gacttatttt tgaaaaggag
    45721 agacagaaaa tggcgataga aaagctatca cccggcatgc aacagtatgt ggatattaaa
    45781 aagcaatatc cagatgcttt tttgctcttt cggatgggtg atttttatga attattttat
    45841 gaggatgcgg tcaatgctgc gcagattctg gaaatttcct taacgagtcg caacaagaat
    45901 gccgacaatc cgatccctat ggcgggtgtt ccctatcatt ctgcccaaca gtatatcgat
    45961 gtcttgattg agcagggtta taaggtggct atcgcagagc agatggaaga tcctaaacaa
    46021 gcagttgggg ttgttaaacg agaggttgtt caggtcatta cgccagggac agtggtcgat
    46081 agcagtaagc cggacagtca gaataatttt ttggtttcca tagaccgcga aggcaatcaa
    46141 tttggcctag cttatatgga tttggtgacg ggtgactttt atgtgacagg tcttttggat
    46201 ttcacgctgg tttgtgggga aatccgtaac ctcaaggctc gagaagtggt gttgggttat
    46261 gacttgtctg aggaagaaga acaaatcctc agccgccaga tgaatctggt actctcttat
    46321 gaaaaagaaa gctttgaaga ccttcattta ttggatttgc gattggcaac ggtggagcaa
    46381 acggcatcta gtaagctgct ccagtatgtt catcggactc agatgaggga attgaaccac
    46441 ctcaaacctg ttatccgcta cgaaattaag gatttcttgc agatggatta tgcgaccaag
    46501 gctagtctgg atttggttga gaatgctcgc tcaggtaaga aacaaggcag tcttttctgg
    46561 cttttggatg aaaccaaaac ggctatgggg atgcgtctct tgcgttcttg gattcatcgc
    46621 cccttgattg ataaggaacg aatcgtccaa cgtcaagaag tagtgcaggt ctttctcgac
    46681 catttctttg agcgtagtga cttgacagac agtctcaagg gtgtttatga cattgagcgc
    46741 ttggctagtc gtgtttcttt tggtaaaacc aatccaaagg atctcttgca gttggcgact
    46801 accttgtcta gtgtgccacg gattcgtgcg attttagaag ggatggagca acctactcta
    46861 gcctatctca tcgcacaact ggatgcaatc cctgagttgg agagtttgat tagcgcagcg
    46921 attgctcctg aagctcctca tgtgattaca gatgggggaa ttatccggac tggatttgat
    46981 gagactttag acaagtatcg ttgcgttctc agagaaggga ctagctggat tgctgagatt
    47041 gaggctaagg agcgagaaaa ctctggtatc agcacgctca agattgacta caataaaaag
    47101 gatggctact attttcatgt gaccaattcg caactgggaa atgtgccagc ccactttttc
    47161 cgcaaggcga cgctgaaaaa ctcagaacgc tttggaaccg aagaattagc ccgtatcgag
    47221 ggagatatgc ttgaggcgcg tgagaagtca gccaacctcg aatacgaaat atttatgcgc
    47281 attcgtgaag aggtcggcaa gtacatccag cgtttacaag ctctagccca aggaattgcg
    47341 acggttgatg tcttacagag tctggcggtt gtggctgaaa cccagcattt gattcgacct
    47401 gagtttggtg acgattcaca aattgatatc cggaaagggc gccatgctgt cgttgaaaag
    47461 gttatggggg ctcagaccta tattccaaat acgattcaga tggcagaaga taccagtatt
    47521 caactggtta cagggccaaa catgagtggg aagtctacct atatgcgtca gttagccatg
    47581 acggcggtta tggcccagct gggttcctat gttcctgctg aaagcgccca tttaccgatt
    47641 tttgatgcga tttttacccg tatcggagca gcagatgact tggtttcggg tcagtcaacc
    47701 tttatggtgg agatgatgga ggccaataat gccatttcgc atgcgaccaa gaactctctc
    47761 attctctttg atgaattggg acgtggaact gcaacttatg acgggatggc tcttgctcag
    47821 tccatcatcg aatatatcca tgagcacatc ggagctaaga ccctctttgc gacccactac
    47881 catgagttga ctagtctgga gtctagttta caacacttgg tcaatgtcca cgtggcaact
    47941 ttggagcagg atgggcaggt caccttcctt cacaagattg aaccgggacc agctgataaa
    48001 tcctacggta tccatgttgc caagattgct ggcttgccag cagacctttt agcaagggcg
    48061 gataagattt tgactcagct agagaatcaa ggaacagaga gtcctcctcc catgagacaa
    48121 actagtgctg tcactgaaca gatttcactc tttgataggg cagaagagca tcctatccta
    48181 gcagaattag ctaaactgga tgtgtataat atgacaccta tgcaggttat gaatgtctta
    48241 gtagagttaa aacagaaact ataaaaccaa gactcactag ttaatctagc tgtatcaagg
    48301 agacttcttt gacaattctc cacttttttg ctagaataac atcacacaaa cagaatgaaa
    48361 aggagctgac gcattgtcgc tcccttttgt ctatttttta aggagaaagt atgctgattc
    48421 agaaaataaa aacctacaag tggcaggccc tggcttcgct cctgatgaca ggcttgatgg
    48481 ttgctagttc acttctgcaa ccgcgttatc tgcaggaagt cttaggcgcc ctccttgctg
    48541 ggaaatatga agctatttat agtatcgggg cttggttgat tggtgtggcc gtagtcggtc
    48601 tagttgctgg tggactcaat gttgtcctcg cagcctatat tgcccaagga gtttcatccg
    48661 accttcggga ggatgccttc cgtaaaattc aaaccttttc ttatgctgat attgaacaat
    48721 ttaatgcggg aaatctagtc gttcgaatga caaatgatat caaccagatt cagaacgttg
    48781 tcatgatgac cttccagatt cttttcagac ttcccctctt gttcatcggt tcgtttatcc
    48841 tagcggttca aaccttacct tctctgtggt gggtgattgt tctcatggta gtcttgattt
    48901 ttggtttgac tgctgtcatg atgggaatga tggggcctcg ttttgccaag tttcaaaccc
    48961 ttcttgagcg catcaatgcc attgccaagg aaaatttacg tggcgttcgt gtggtcaagt
    49021 cctttgtcca agaaaaagag caatttgcta agtttacaga ggtctcagac gagcttcttg
    49081 gtcaaaacct ttacattggt tatgcctttt cagtagtgga accctttatg atgttggttg
    49141 gttacggggc ggtcttcctc tctatttggc tggtcgcggg aatggttcag tcggatccgt
    49201 ctgttgttgg ttccatcgct tcttttgtta attacctaag ccagattatc tttaccattg
    49261 ttatggttgg atttttggga aattctgtca gccgtgccat gatttccatg cgtcgtattc
    49321 gagaaattct tgacgcagag ccagctatga ccttcaagga tatcccagat gaagagttgg
    49381 ttggaagcct tagctttgaa aatgtgacct ttacctatcc aatggacaag gaaccgatgc
    49441 tgaaagatgt gagctttact attgaacctg gtcaaatggt tggtgtagtt ggagcgactg
    49501 gtgcaggaaa gtcaaccttg gctcaattga ttccacgtct ctttgatcca caggaagggg
    49561 ctatcaaaat cggaggtaag gatattcgag aagtgagtga aggaaccctg cgtaaaacag
    49621 tttccatcgt tctccaacgt gccattcttt ttagtggaac gattgcagat aacttgagac
    49681 aggggaaggg aaatgctact ctatttgaaa tggagcgcgc agccaatatt gcccaggcta
    49741 gtgaattcat tcatcgtatg gagaaaacct ttgaaagtcc agttgaagaa cggggaacca
    49801 atttctctgg tggacaaaaa caaaggatgt cgattgcgcg tgggattgtc agcaatccac
    49861 gtattctgat ttttgatgat tcgacctcag ccttggatgc caaatcagag cgcttggtgc
    49921 aagaagcttt gaataaggac ttgaagggga cgacaaccat tattattgct caaaaaatta
    49981 gctcggttgt ccatgcagac aagatcttgg ttctaaatca aggacgattg attggtcaag
    50041 gcacgcatgc agacttggtt gccaacaatg ccgtttaccg tgaaatctat gaaacacaga
    50101 aatgaaagac aaactataag aaaagtcaat agttttatct aaactatttc ttatttcaat
    50161 ttgatgattt ggcgatgatt ttagagcacg gcaaaaagct attgaaaaag tccatttttt
    50221 caaaggtaat cctgtgttaa tttcagaaat tacatcactt tttgttcgtc aaatggcagc
    50281 tcttttttag gatataaaac agggttcgga taagtttttt tgcaaggtgg atgatggcta
    50341 cattgtaatg ttttccttgt tctaacttag tcttaagata ggccttaaaa gcaggtgaaa
    50401 agcgagggca tgctttggca gcttgtatga gtacctaccg cagatgaggg gaaccccgtt
    50461 tgaccattct tcctgctaaa tcaatctgac ctgactgata aatagaagaa tccagtccag
    50521 cgaaagcttg taattgagca ggattatcaa aggcatgaat atttcgaatc tcggctaaaa
    50581 tgaccgcccc taaacgaccc ccaatcccag taaccgtcgt gatgaccgag ttgaactcag
    50641 ccatcaagtc attgacacat tttttcgcct tgtcaatgag cctcttgtaa tgtttgatgt
    50701 tttcattaca agagataaaa cgtttatgcg ttatcaaact cattaccaat tgaaacaaaa
    50761 agctgtggtt agatcctttc ggaaattgtc aagcgattgg aggaaatgaa ctaatccaca
    50821 gcggcttatt ccaagtatac cacttgggct ttggcagtag ctaactgcgc taaatataat
    50881 ataaggagga gtaaaatgaa gacagttcaa tttttttggc attattttaa ggtctacaag
    50941 ttctcatttg tagttgtcat cctgatgatt gttctggcga cttttgccca agccctcttt
    51001 ccagtctttt ctggacaagc ggtgacgcag ctagccaatt tagttcaagc ttatcaaaat
    51061 ggcaatccag aacttgtatg gcaaagccta tcaggaatca tggtcaatct tggcctgctg
    51121 gttttggttc tatttatctc tagtgtaata tacatgtgtc tcatgacgcg cgtgattgca
    51181 gaatcgacca acgagatgcg caaaggcctc tttggtaagc ttgctcagtt gacggtttct
    51241 ttctttgacc gtcgacaaga tggcgatatc ctgtctcatt ttaccagtga tttggataat
    51301 atcctccaag cctttaacga aagcttgatt caggtcatga gcaatattgt tttatacatt
    51361 ggtctgattc ttgtcatgtt ttcgagaaat gtgacgctgg ctctcatcac cattgccagc
    51421 accccattgg ctttccttat gctgattttc atcgtgaaaa tggcacgtaa atacaccaac
    51481 ctccagcaga aagaggtagg gaagctcaac gcctatatgg atgagagcat ctcaggccaa
    51541 aaagccgtga ttgtgcaagg aattcaagag gatatgatgg caggatttct tgaacaaaat
    51601 gagcgcgtgc gcaaggcaac ctttaaagga agaatgttct caggaattct tttccctgtc
    51661 atgaatggga tgagcctgat taatacagcc atcgtcatct ttgctggttc ggctgtactt
    51721 ttgaatgata agtctattga aacaagtaca gccctaggtt tgattgttat gtttgcacaa
    51781 ttttcacagc agtactacca gcctattatc caagttgcag cgagttgggg aagccttcag
    51841 ttggccttta ctggagctga acgaattcag gaaatgtttg atgcagagga ggaaatccga
    51901 cctgaaaagg ctccaacctt cactaagttg caagaaagtg ttgaaatcag tcatatcgat
    51961 ttttcatact tgcctgataa acctattttg aaagatgtca gcatttctgc ccctaaaggc
    52021 cagatgacag cagttgttgg gcctacaggt tcaggaaaaa cgactattat gaacctcatc
    52081 aatcgctttt atgatgttga tgctggtggt atttattttg atggtaaaga cattcgtggc
    52141 tatgacttag atagtcttag aagcaaggtg ggaattgtat tgcaagattc ggtcttgttt
    52201 agcggaacga ttcgagacaa tatccgattt ggtgtgccag atgctaatca ggaaatggtt
    52261 gaggtagcag caaaagcaac ccacattcac gactatatcg aaagtttgcc tgataagtac
    52321 gatactctta ttgatgatga ccagagcatc ttttcaacag ggcagaagca attgatttca
    52381 atcgctcgaa ccctgatgac agatccagaa gttctcattc tcgatgaagc aacttcaaac
    52441 gtagatacgg tgacggaaag caagattcag catgccatgg aggtggttgt agcaggtaga
    52501 actagtttcg tcattgccca ccgcttgaaa accattctca atgcagatca gattattgtc
    52561 cttaaagatg gagaagtcat tgaacgtggt aaccaccatg aacttttgaa gctaggtggc
    52621 ttttattcag aactctatca caatcaattt gttttcgaat aagaaagaag ttgtcctatg
    52681 tgggcagctt tttcttgtcc ataaaaaatg tttatcacag ccttaaaaaa aacatattag
    52741 acgaaagtca ttttgagtga tatgatagga ctatcgttag tattcgaaag gagaggcatc
    52801 atggctagaa cggttgtagg agttgctgca aatctatgtc ccgtagacgc agaaggcaaa
    52861 atcattcatt catctgtatc ttgtagattc gcagagatca ttcgtcaagt cggtggtctc
    52921 cctttagtca ttcctgttgg tgatgagtca gttgtacgtg attatgtgga aatgattgac
    52981 aaactcattt tgacaggagg ccaaaatgtt catcctcagt tttatggaga gaaaaagacc
    53041 gtcgaaagcg atgattacaa tctggtccgt gacgaatttg aattggcact cttgaaggaa
    53101 gcgcttcgtc agaataaacc aattatggca atctgtcgcg gtgtccaact tgtcaatgtt
    53161 gcctttggtg gaaccctcaa tcaagaaatc gaaggtcact ggcaaggact acctttcggg
    53221 acatctcact ctattgaaac agtagaagga agcgtggtgg ctaagctatt tgggaaagaa
    53281 agtcaggtca actcagtcca tcgtcaaagc attaaagatt tggcacctaa tttccgtgta
    53341 actgctattg attcaagaga ccaaactatt gaagcgattg agtctatcga cgagcaccgc
    53401 attatcggtt tacagtggca tccagagttt ctggttaatg aagaagatgg caatttagaa
    53461 ttatttgagt atttattgaa tgaactgtaa cgattggaac atctggtcgt tctttctttt
    53521 attttttcaa aatttttaga atgtggcatt ttacgcaaac gtttgaattc tgataaaaat
    53581 tggagaaatt cgacaaaaaa acttgaaaaa aacgaaggta agcgttatga tagaaaagaa
    53641 gaaatattgg aggaagaaca tgtcacatat taaatttgat tattcaaaag ttttagacaa
    53701 atttgttgca ccacatgaag tggaatacat gcaatcacaa gtaacagcag cagatgaatt
    53761 gatccgtaaa ggaactggtg ctggtagcga cttcttggga tggttggacc ttcctgaaaa
    53821 atacgaccgc gaagaatttg accgcatctt gaaagctgct gagcaaatca agtcagacag
    53881 cgatgttttg gttgtgatcg gtattggtgg atcttacctt ggtgcaaaag cagcaatcga
    53941 cttcttgaat caccattttg ctaacttgca aacaaaagaa gaacgcaaag ctccacaaat
    54001 cctttacgca ggaaactcaa tctcatctac ttaccttgct gacttggtag agtatgttgc
    54061 agacaaagac ttctcagtaa acgtaatttc taaatcaggt acaacaactg aaccagcgat
    54121 tgctttccgt gtctttaaag aactcttggt taagaaatac ggtcaagaag aagctaacaa
    54181 acgtatctat gcaacaactg accgccaaaa gggtgctgtt aaggttgaag cagacgctaa
    54241 cggttgggga acatttgttg ttccagatga tatcggtgga cgcttctcag tattgacagc
    54301 cgttggtttg cttccaatcg cagcatcagg agctgacatc aaagctctta tggaaggtgc
    54361 gaatgcagct cgcaaagact acacttcaga caaaatctct gaaaacgaag cttaccaata
    54421 cgcagtcgtt cgtaacatcc tttatcgtaa aggctatgca actgagatct tggtaaacta
    54481 tgagccatca cttcaatact tctcagaatg gtggaaacaa ttggctggtg aatcagaagg
    54541 aaaagaccaa aaaggtatct acccaacttc agccaacttc tcaactgact tgcactcact
    54601 tggtcaattt atccaagaag gaactcgtat catgtttgaa acagttgtcc gtgttgacaa
    54661 acctcgtaaa aacgtgctta ttcctacttt ggaagaagac cttgacggac ttggttacct
    54721 tcaaggaaaa gacgttgact ttgtaaacaa aaaagcaact gacggtgttc ttcttgccca
    54781 cacagatggt gatgtaccaa acatgtatgt gactcttcca gagcaagacg ctttcactct
    54841 tggttacact atctacttct tcgaattggc aattgccctt tcaggttact tgaatgctat
    54901 caacccattt gaccaaccag gtgttgaagc ttataaacgt aacatgtttg cccttcttgg
    54961 aaaaccagga tttgaagaat tgagcaaaga acttaacgca cgtctataat agaagaaaag
    55021 agtggtttgc ccactctttt tactctcttt atccatagaa attggactca gccaagactt
    55081 gtgatataat atagaaagca aaaaggcaga cgcctagata ataggagaaa ctatgtcaaa
    55141 agatatccgc gtacgttacg caccaagtcc aacaggacta ctacacatcg gaaatgcccg
    55201 tacagcattg tttaactact tgtatgcgcg ccatcatggt ggaacatttc tcatccgtat
    55261 cgaagatact gaccgtaaac gccatgtcga ggatggtgaa cgttcacaac ttgaaaacct
    55321 tcgctggtta ggcatggatt gggatgaaag tccagaatca catgagaatt atcgccagtc
    55381 tgagcgtttg gacttgtatc aaaaatacat tgaccaacta ttagctgaag gaaaagccta
    55441 taaatcttac gttacagaag aagagttggc agctgaacgt gaacgtcaag aagtagctgg
    55501 cgaaacacca cgctacatca atgaatacct tggtatgagt gaagaagaaa aagcggctta
    55561 tatcgcagaa cgtgaagcag ctggtatcat accaacagtt cgtttggctg tcaatgagtc
    55621 aggtatctac aagtggcatg atatggtcaa aggtgatatc gaatttgaag gtggcaatat
    55681 cggcggtgac tgggttatcc aaaagaaaga cggttaccca acttacaact ttgccgttgt
    55741 tatcgatgac cacgatatgc aaatctctca tgttatccgt ggagatgacc atattgctaa
    55801 tacaccaaaa cagcttatgg tctatgaagc tcttggttgg gaagctccag agtttggtca
    55861 catgaccttg attatcaact ctgagactgg taagaagtta tctaaacgtg atactaatac
    55921 acttcaattt atcgaagatt accgaaagaa aggttacctt ccagaagcag tctttaactt
    55981 tattgctctt cttggttgga acccaggtgg tgaagatgag attttctctc gtgaagaact
    56041 cattaaactt tttgatgaaa accgcctcag caagtcacca gcagcctttg atcagaaaaa
    56101 attagactgg atgagcaatg attatatcaa gaatgcagac cttgaaacca tctttgaaat
    56161 ggcaaaacca ttcttagagg aagcaggccg tttgactgac aaggctgaaa aattagttga
    56221 gctctataaa ccacaaatga aatcagtaga tgagattatc ccattgacag atcttttctt
    56281 ctcagatttc ccagaattga cagaagcaga gcgcgaagtc atgacgggtg aaacagttcc
    56341 aacagttctt gaagcattca aagcaaaact tgaagcgatg acagatgatg aatttgtgac
    56401 agaaaatatc ttcccacaaa ttaaagcagt ccaaaaagaa acaggtatta aagggaaaaa
    56461 tcttttcatg cctattcgta tcgcagtttc aggcgaaatg catgggccag aattaccaga
    56521 tacaattttc ttgcttggac gtgaaaaatc aattcagcat atcgaaaaca ttctaaaaga
    56581 aatctctaaa taaagaggat acaataatgg acatctggga aaagatgtac gaagaagcac
    56641 agaaactata caatccacat gaagtatcag actttgttta tgccaatcat gttgtagctg
    56701 cagtagaagc aggagatgga caaatattta caggattctg tatggaggga acctgtggtg
    56761 ttttccatct ctgcgcagaa cgggcgaccc tcttcaatat gtaccaattt tcaggacaaa
    56821 ctaaggttaa gaaagtatta gcctttcgag acaaaccacc ttatggtgga agttcagcca
    56881 tgccttgcgg tgcttgtaga gaattccttt tagagcttaa tgctgaaaat aaagatgcag
    56941 aattcatgat ggactataat ataagaaaaa cagttaaagt cgcagaacta atcccttatt
    57001 ggtggggaga agaacgtgct tctaagttta atgagtgata gaagagtcag tataattctg
    57061 gctcttttta ctataagttg aaaaaataaa aaaaattaga aaaagtagtt gacaaaattt
    57121 gaaaagactg tataatagta agagttgaaa ataacaactc aggtccgttg gtcaaggggt
    57181 taagacaccg ccttttcacg gcggtaacac gggttcgaat cccgtacgga ctatggtatg
    57241 ttgcgtcagg accacttgat gaaaaaaagt ttaaaaaa
//
LOCUS       DAVLBE010000008        56147 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.008, whole genome shotgun sequence.
ACCESSION   DAVLBE010000008 DAVLBE010000000
VERSION     DAVLBE010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 56147)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56147)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56147
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.008"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            67..351
                     /locus_tag="VXB91_000504"
     CDS             67..351
                     /locus_tag="VXB91_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0470008.1"
                     /translation="MDWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDVEKL
                     LDSKELTRFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            344..582
                     /locus_tag="VXB91_000505"
                     /pseudo
     CDS             344..582
                     /locus_tag="VXB91_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397100.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            678..896
                     /locus_tag="VXB91_000506"
     CDS             678..896
                     /locus_tag="VXB91_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0470009.1"
                     /translation="MMSIREQDLQDIGAIIKYKNFHSPFDTFKYLKDMGFDTIDLSVL
                     LEGFSYAYGMDWLEKFFKENQDKLREFY"
     gene            complement(1263..3587)
                     /gene="pflB"
                     /locus_tag="VXB91_000507"
     CDS             complement(1263..3587)
                     /gene="pflB"
                     /locus_tag="VXB91_000507"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HEV0470010.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIEPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDRYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
     gene            3981..5042
                     /gene="dinB"
                     /locus_tag="VXB91_000508"
     CDS             3981..5042
                     /gene="dinB"
                     /locus_tag="VXB91_000508"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HEV0470011.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIKDNPKLRGKPVIIGSD
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKAVGLQIRAI
                     FKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGISYNKF
                     LAKMASDYQKPHGLTVILPEQAEDFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILLAEEDIKKEL
                     TLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSLAQKTQDASQISQIALQLYE
                     ELSKKERGVRLLGITMTGF"
     gene            complement(5189..6034)
                     /locus_tag="VXB91_000509"
     CDS             complement(5189..6034)
                     /locus_tag="VXB91_000509"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HEV0470012.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
     gene            6289..7260
                     /locus_tag="VXB91_000510"
     CDS             6289..7260
                     /locus_tag="VXB91_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HEV0470013.1"
                     /translation="MLYVGIDIAKNKHDVTALNVPGKTVLKPLTFSNNKAGFELLDLS
                     LRQLNQDCLIALKLLSDPNREQFQHDNRQVDLKILARHIHRLKKKQSDWKVQYTRCLD
                     IIFPELDKIVGKHSEYTYQLLTRYPNPQKRIEAGFDKLIEIKRLTASKIQDILSVAPR
                     SIETTSPAREFEIIEIIKHYKRLIDKAETCVNDLMAEFNSVITTVTGIGGRLGAVILA
                     EIRNIHAFDNPAQLQAFAGLDSSIYQSGQIDLAGRMIKRGSPHLRWALIQAAKVCARF
                     SPAFKAYLKTKLEQGKHYNVAIIHLAKKLIRTLFYILKKSCHLTNKK"
     gene            complement(7459..9348)
                     /locus_tag="VXB91_000511"
     CDS             complement(7459..9348)
                     /locus_tag="VXB91_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HEV0470014.1"
                     /translation="MKKTFFLLVLGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKVQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGAEKLFFHTGKLFREGTIEKSNLDYTIRLDNLPAKRGVELHAYWSRTDFASARDQG
                     LKGNRLEEFNKIEDSIVREKDQSKQLVTWVLPSILSISLLLSVCFYFIYRRKTTPSVK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVIDRG
                     NVSIISEGDAVGLRLVKEDGLSRFERDCLNLAFSGKKEATLSNFFADYKVSDSLYRRA
                     KVSDEKRIQARGLQLKSSFEEVLNQMQEGVRKRVSFWGLPDYYRPLTGLEKTLQVGMG
                     VLTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLRLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDKAELESIVVWNRLLVYATLFGYADKVSHLMKVHQIQ
                     VENPDINLYVAYGWHSMFYHSSAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
     gene            9486..11051
                     /locus_tag="VXB91_000512"
     CDS             9486..11051
                     /locus_tag="VXB91_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEV0470015.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKEPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEIAFSSSYYTSEPVLLVKKDSAYASAKSLDDFNGAKITSQQGVYLYD
                     LIAQIPGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMIQVEPGF
                     KTGEEDTAIAIGLRKNDNRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTIIGLIIGLAIGVFRTAPLSENKAIYG
                     LQKLVGWVLNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMRKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            11051..11791
                     /locus_tag="VXB91_000513"
     CDS             11051..11791
                     /locus_tag="VXB91_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV0470016.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEKIAKENLEKVGMGERYWQAKPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYLK"
     gene            complement(11900..12115)
                     /locus_tag="VXB91_000514"
     CDS             complement(11900..12115)
                     /locus_tag="VXB91_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0470017.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNYEKFED"
     gene            complement(12986..14236)
                     /gene="ilvA"
                     /locus_tag="VXB91_000515"
     CDS             complement(12986..14236)
                     /gene="ilvA"
                     /locus_tag="VXB91_000515"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HEV0470018.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIQTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
     gene            complement(14286..14642)
                     /locus_tag="VXB91_000516"
     CDS             complement(14286..14642)
                     /locus_tag="VXB91_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEV0470019.1"
                     /translation="MNITNLFSIKTGCDETDRQLQKLFFQLDLQLGELTDQLRKLDSN
                     FVPRSQFVDTLDLNDVEYKEILNYFIFHRNDSEESLVEWLYDWISTNRYELPKEFSIR
                     MAHKYHESVTEIFGDE"
     gene            complement(14880..15116)
                     /locus_tag="VXB91_000517"
     CDS             complement(14880..15116)
                     /locus_tag="VXB91_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0470020.1"
                     /translation="MLADQNKADWSYDENAVINIYDDANFEDGRLHMTFEQFFKLAQI
                     AREEGLEIHSPFERAGATKSARYIAKWILRNKKY"
     gene            complement(15223..16245)
                     /gene="ilvC"
                     /locus_tag="VXB91_000518"
     CDS             complement(15223..16245)
                     /gene="ilvC"
                     /locus_tag="VXB91_000518"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEV0470021.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYTVAEATKLADVIMILAPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGPRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            complement(16311..16787)
                     /gene="ilvN"
                     /locus_tag="VXB91_000519"
     CDS             complement(16311..16787)
                     /gene="ilvN"
                     /locus_tag="VXB91_000519"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HEV0470022.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            complement(16780..18480)
                     /locus_tag="VXB91_000520"
     CDS             complement(16780..18480)
                     /locus_tag="VXB91_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HEV0470023.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVQFHA
                     "
     gene            complement(18680..20347)
                     /locus_tag="VXB91_000521"
     CDS             complement(18680..20347)
                     /locus_tag="VXB91_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HEV0470024.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDTVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
     gene            complement(20350..20715)
                     /locus_tag="VXB91_000522"
     CDS             complement(20350..20715)
                     /locus_tag="VXB91_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEV0470025.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            complement(20872..21060)
                     /locus_tag="VXB91_000523"
     CDS             complement(20872..21060)
                     /locus_tag="VXB91_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HEV0470026.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            complement(21176..21661)
                     /locus_tag="VXB91_000524"
     CDS             complement(21176..21661)
                     /locus_tag="VXB91_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HEV0470027.1"
                     /translation="MKEEKKAIVLGADNAYMDKVETTIKSLCVHHYNLKFYVFNDDLP
                     REWFQLMEKRLETLNSEIVNVQIDSSILKGYRLPFEGLSYAAFFRYFIPKYVSESRVL
                     YLDSDIVVRKSIDELWDLDLTAIPLAAVRDDFYTHNFNSGVLLINNGMWRAENVTQDL
                     I"
     gene            complement(21930..23474)
                     /locus_tag="VXB91_000525"
     CDS             complement(21930..23474)
                     /locus_tag="VXB91_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HEV0470028.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYEQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLEIFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVINAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMSPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            23687..23989
                     /gene="gatC"
                     /locus_tag="VXB91_000526"
     CDS             23687..23989
                     /gene="gatC"
                     /locus_tag="VXB91_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HEV0470029.1"
                     /translation="MKITQEEVTHVANLSKLRFSEEETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVAEEGTDRDRLFKNVPEQDNYYIKVPAILDDGGDA"
     gene            23989..25455
                     /gene="gatA"
                     /locus_tag="VXB91_000527"
     CDS             23989..25455
                     /gene="gatA"
                     /locus_tag="VXB91_000527"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HEV0470030.1"
                     /translation="MTFNNKTIEELHNLLVSKEISATELTQATLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDADNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWNHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLNAIASEDAKDSTSAPVRIADFTSKIGQDIKGMKIALPKEYLGEGIDPEVKE
                     TILNAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKYSEETIYQAAAAFEATTDYHKQQPVIFGGDN"
     gene            25455..26897
                     /gene="gatB"
                     /locus_tag="VXB91_000528"
     CDS             25455..26897
                     /gene="gatB"
                     /locus_tag="VXB91_000528"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HEV0470031.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDIHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVKLEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEVQRQAEILRSGGQIRQETRRYDEANKATILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMRTELPEFPKERRARYVSDLGLSDYDASQLTANKVTSDFFEKAVA
                     LGGDAKQVSNWLQGEVAQFLNAEGKTLEQIELTPENLVEMIAIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            27026..27586
                     /gene="efp"
                     /locus_tag="VXB91_000529"
     CDS             27026..27586
                     /gene="efp"
                     /locus_tag="VXB91_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HEV0470032.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            27608..27997
                     /locus_tag="VXB91_000530"
     CDS             27608..27997
                     /locus_tag="VXB91_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEV0470033.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGIYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            27990..28412
                     /gene="nusB"
                     /locus_tag="VXB91_000531"
     CDS             27990..28412
                     /gene="nusB"
                     /locus_tag="VXB91_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HEV0470034.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTDVETACRFAYTHDREDT
                     AVQLPAFLIDLVSGVQAKKEELDKQITQHLKAGWTIERLTLVERNLLRLGVFEITSFD
                     TPQLVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(28461..28688)
                     /locus_tag="VXB91_000532"
     CDS             complement(28461..28688)
                     /locus_tag="VXB91_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0470035.1"
                     /translation="MLSGLIFGLSHLILSHRDPISLLYYSLIGFFFALVYRSTDNLRL
                     TILCHSFFNFLNHAKPIWIFVYNYIYYHFFR"
     gene            complement(29179..29364)
                     /gene="briC"
                     /locus_tag="VXB91_000533"
     CDS             complement(29179..29364)
                     /gene="briC"
                     /locus_tag="VXB91_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HEV0470036.1"
                     /translation="MTGTETFTVISTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRTG"
     gene            complement(29523..30290)
                     /locus_tag="VXB91_000534"
     CDS             complement(29523..30290)
                     /locus_tag="VXB91_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HEV0470037.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEVGLSS
                     KELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY"
     gene            complement(30287..31153)
                     /locus_tag="VXB91_000535"
     CDS             complement(30287..31153)
                     /locus_tag="VXB91_000535"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HEV0470038.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            complement(31190..32557)
                     /gene="accC"
                     /locus_tag="VXB91_000536"
     CDS             complement(31190..32557)
                     /gene="accC"
                     /locus_tag="VXB91_000536"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HEV0470039.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVEKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASRNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            complement(32569..32991)
                     /gene="fabZ"
                     /locus_tag="VXB91_000537"
     CDS             complement(32569..32991)
                     /gene="fabZ"
                     /locus_tag="VXB91_000537"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HEV0470040.1"
                     /translation="MIDIQGIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGILTFAIGN"
     gene            complement(32988..33473)
                     /locus_tag="VXB91_000538"
     CDS             complement(32988..33473)
                     /locus_tag="VXB91_000538"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HEV0470041.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPSPVAPTSAPAETVAEEVPAPAEASVATEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            complement(33476..34711)
                     /gene="fabF"
                     /locus_tag="VXB91_000539"
     CDS             complement(33476..34711)
                     /gene="fabF"
                     /locus_tag="VXB91_000539"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HEV0470042.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            complement(34733..35464)
                     /gene="fabG"
                     /locus_tag="VXB91_000540"
     CDS             complement(34733..35464)
                     /gene="fabG"
                     /locus_tag="VXB91_000540"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HEV0470043.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVIAIDGGLSM"
     gene            complement(35498..36418)
                     /gene="fabD"
                     /locus_tag="VXB91_000541"
     CDS             complement(35498..36418)
                     /gene="fabD"
                     /locus_tag="VXB91_000541"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HEV0470044.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEAAPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTSLLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTTHLAHVEDQASLVALLEK"
     gene            complement(36411..37385)
                     /gene="fabK"
                     /locus_tag="VXB91_000542"
     CDS             complement(36411..37385)
                     /gene="fabK"
                     /locus_tag="VXB91_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HEV0470045.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     VSIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVE
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWTGVVRND"
     gene            complement(37504..37728)
                     /locus_tag="VXB91_000543"
     CDS             complement(37504..37728)
                     /locus_tag="VXB91_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEV0470046.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            complement(37788..38762)
                     /locus_tag="VXB91_000544"
     CDS             complement(37788..38762)
                     /locus_tag="VXB91_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HEV0470047.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGEELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANDRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            complement(38762..39196)
                     /locus_tag="VXB91_000545"
     CDS             complement(38762..39196)
                     /locus_tag="VXB91_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV0470048.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            complement(39290..40075)
                     /locus_tag="VXB91_000546"
     CDS             complement(39290..40075)
                     /locus_tag="VXB91_000546"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HEV0470049.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            40444..41808
                     /locus_tag="VXB91_000547"
     CDS             40444..41808
                     /locus_tag="VXB91_000547"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HEV0470050.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREVGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRQLTPIKEEEILRQLVQKAKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYNAFFGE
                     SKED"
     gene            41811..42182
                     /locus_tag="VXB91_000548"
     CDS             41811..42182
                     /locus_tag="VXB91_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HEV0470051.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGRKISRHFEVFTDKGKFLFASKDSGAILKIAREKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            42396..43670
                     /gene="serS"
                     /locus_tag="VXB91_000549"
     CDS             42396..43670
                     /gene="serS"
                     /locus_tag="VXB91_000549"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HEV0470052.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVEAAVLNEMKEIDAKRRNILVK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGTDEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLTNYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSAAKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEALRPYMGGAEVIKP"
     gene            complement(43695..44594)
                     /locus_tag="VXB91_000550"
     CDS             complement(43695..44594)
                     /locus_tag="VXB91_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HEV0470053.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDTLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACSGRRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPTWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMAQGILKLPFLDYLVLAE
                     TIICLTILFFVLGAYLIWLRKKV"
     gene            complement(44704..45252)
                     /locus_tag="VXB91_000551"
     CDS             complement(44704..45252)
                     /locus_tag="VXB91_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HEV0470054.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            complement(45470..46792)
                     /locus_tag="VXB91_000552"
     CDS             complement(45470..46792)
                     /locus_tag="VXB91_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HEV0470055.1"
                     /translation="MLELLKSIDAFAWGPPLLILLVGTGIYLTMRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSITESIQNTTTISPAITALVLSVFVAIAVFGGLKSISKVSTTVVPFMALIYI
                     LGTLTVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALT
                     QSAFSTVFSHFGPALLTIFLVLFTFTTILGWNYYGERCFEFLFGARFIWLYRVFFVLM
                     VLLGGFIELDMVWIIADIVNALMALPNLIALLVLSPVVIAETKKYFDK"
     regulatory      complement(46883..46971)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            complement(47135..49471)
                     /locus_tag="VXB91_000553"
     CDS             complement(47135..49471)
                     /locus_tag="VXB91_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HEV0470056.1"
                     /translation="MNKKILETLEFDKVKALFEPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLASREL
                     QSFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESQVRDVLQDLLKQKGQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVYFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQIGLIKMTLEEKEFDLVQAQQEKPV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDTFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     gene            complement(49575..50123)
                     /locus_tag="VXB91_000554"
     CDS             complement(49575..50123)
                     /locus_tag="VXB91_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HEV0470057.1"
                     /translation="MISFLLLLVLVWGFYIGYRRGLLLQVYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEGQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIVYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPITTSWLKQIWVTNLIG"
     gene            complement(50120..50422)
                     /gene="zapA"
                     /locus_tag="VXB91_000555"
     CDS             complement(50120..50422)
                     /gene="zapA"
                     /locus_tag="VXB91_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HEV0470058.1"
                     /translation="MANLNRFKFTFGKKTLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            50509..51390
                     /locus_tag="VXB91_000556"
     CDS             50509..51390
                     /locus_tag="VXB91_000556"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HEV0470059.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFGYQAVEQTSGQNLPLIGTDEVGNGSYFGGLAVVAAFV
                     TPDQHDFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQEANRFSNPISLEEKAEG
                     KYLAVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQGLSFC
                     AKLHFKNTEKAKKRLER"
     gene            51394..52008
                     /gene="lepB"
                     /locus_tag="VXB91_000557"
     CDS             51394..52008
                     /gene="lepB"
                     /locus_tag="VXB91_000557"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEV0470060.1"
                     /translation="MNSFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRFWPITRIGTF"
     gene            52242..54608
                     /locus_tag="VXB91_000558"
     CDS             52242..54608
                     /locus_tag="VXB91_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HEV0470061.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYTFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGIAGLSAKNREAFVSTLRLNYGTEMVLAKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQACMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLVRILEKGKQKSHDLETIQKHITTIEEELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDFRKKNNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDEFSMVDTWLANQL
                     FSNISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTRLEKIYRQSEESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILGAALRNSIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHYRKGDKVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWDSIPAMIGITDTDLKEIFGK"
     gene            complement(54656..55939)
                     /locus_tag="VXB91_000559"
     CDS             complement(54656..55939)
                     /locus_tag="VXB91_000559"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HEV0470062.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDQKFGEESLYQDVMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVITAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     ENGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKEL
                     AAAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQNLLSADMLKHDITIKKAVELITSTATVK"
BASE COUNT        16622 a        12626 c        10632 g        16267 t
ORIGIN      
        1 taagaaaaac tacatttttg aatataaact acaataatat aaactaaatt ttataggagg
       61 aagacaatgg attggtacga ttatatgata caggcatcca aacaatcaca attcaacgca
      121 agccattggt ttcgctattt gcgaaaagtt atttttgaag actattctta tttaacaaac
      181 caagatgtag aaaagttgct agactccaaa gaactaaccc gttttcaaaa aattagcttg
      241 aagtatgcct ttcaagagca tactccaact cataaatatg tgatttcatt aaataaacct
      301 gctaagttaa ccaatgttca aaaattgatg gagaaataca aacatggata aaatgaaacc
      361 ggtcttccaa gccctaaata agaaattaat tcaggaaaat ctgactttaa caattatggt
      421 tatgtcttag aatatcatgg tttacgtacc acacaagatg ttgatgcttt ttatgaccaa
      481 aatcagaaaa tcaatgaaat tattgctcgt gtaggaaaac agtttaatct taacatccac
      541 gaagagttat ggctcaacaa tcatgttgca aagcaaatat gaacaaacaa cctcccttaa
      601 gtttatgcga atccttgtac tcatttgaga atctgaccgt tttagtagtc cctattgagt
      661 atgtgttagg aatgaagatg atgagtatca gagagcagga tttgcaagat attggtgcaa
      721 ttattaaata caaaaacttt cattcaccat tcgatacctt taaatattta aaagacatgg
      781 gatttgatac tattgacctc tctgttctat tagaaggttt tagttatgct tatggtatgg
      841 attggttaga aaaatttttt aaagaaaatc aagataaact tcgcgaattt tattaacagt
      901 atcaaacaag atgattgtca attagccagt catcttattt ttatgatgaa atgaaataaa
      961 atcggaacaa atcacttaga gaattccagt caatttctag cactgtttga gccgtttcag
     1021 cggactatag taaaatgaaa taagaatagg acaaatcgat caggacagtc aaatcgattt
     1081 ctaagaatgt tttagaagta aaggtgtact attctagttt caatctatta tatttcagat
     1141 tcggtccact attccttccc aaaaacattg catattgcgc cgaaggaatt gctcatacta
     1201 tcccaagcac aaaaccctca gtcgtttgac cgagggttcc ttttcattat tcaaaaactt
     1261 gattagctca atgcatccaa ggcatcatcc attgaaagaa cttcgtggaa gacacgttgt
     1321 gtcaattcag ttttttgttc tggagtgagg tatttagtat ttacacagta tccagagata
     1381 cgtacgataa cgtcttcacc tgacataatt ttttcgtaaa catcgttcaa gtccataacg
     1441 ttcaagttaa cgtgttgtcc accgttttcg aagtaaccat caaggattgt taccaagtta
     1501 tcaacttgtt catcacgagt cttaccaaga gcgcgaggtg atacttgtgt agtcaatgag
     1561 ataccgtcag ctgcataact aaagtcaagg ctagaaagtg agttcaagtt ttgcaaccaa
     1621 ccacctttag ctttgttaga tgggttagca cctggtgaga agaattcaag tttagacaag
     1681 ttcacagaac catcttcgtt gaggtataca cctttgtgaa ctggtgagtt accagtttgt
     1741 ttagagtaag caacgttaga tgtgattgtc aaaagtgata ctgtagcttc tgcgtctttg
     1801 tatagtttgt ggctacgtag acgagttgtg taagcttcga tcaaccattc tgccaattcg
     1861 tttgaacgtg ggtcatcttc accccagcgt gggtagtcac cgattgtttc gtaatcgtag
     1921 atgtagccat cttcgtcacg gattggttta actgtagcgt atttgatagc tgacaatgta
     1981 tcaacagtgt tagcaaatcc acagataccg aatcccatgt tggcacgttg tttagttggc
     2041 aagaaggcca tttgaacagc ttcgtagttg tacctatcag tcatgtagtg gatgatgttc
     2101 aaggcatcta cgtaagtgtc agtcaaccag tcaagagatt tttcaaagtt cgctttaact
     2161 gattcgaatt caagaacttc gtcacggatt ggttcgatat caaatacttt gtagtctttg
     2221 tgaacatcgt cgtaaccacc attcaaacca gtaagaaggg ctttaagaac gtttacacga
     2281 gcaccgaagt actggatgtt gtggcgttgt tcttcatttt ctggatcaag tggagacaca
     2341 cagcatgaga tacagctcat ttcaccatat ccgtctttag ccattgttgt tacaccttcg
     2401 tattggatag aagagtgttt gtggctcatg tgcatacagt agcgacggaa gttgtatggc
     2461 aatttgtcag tccaaagaac tgtcaagttt ggttctggtg agttaccgat gttgtcaaga
     2521 gtgttcaaga aacggtagtc catcttagta acacggtgac gaccgtcgtt acccatacca
     2581 gccatagaag ttgtgataaa ggttgggtca cctgagtaca attggtcata agcttttgta
     2641 cgagcaaatt taactgtacg aagtttcata acgaaatcat caacgaattc ttggatttct
     2701 gattcagtaa atgtaccacg agcaaggtca cgttctgcaa agatgtccaa tacgattggt
     2761 acacgaccta gagatgtagc agcaccgtta atcacacggc agacagccat gaaagcaatg
     2821 ttaacccatt ggattgcttc tttcacgttc atcgctggtt tgcgaacatc aaccccgtaa
     2881 aggtcaccca ggcgaacaac ttgttgcaat gcttggtatt gaaggtttac ttcttcacga
     2941 agacggattg tttcttcatc gatttctttg attgcattcc agtcatttac tttttcttgc
     3001 atcaagtagt ctgcaccgta aagagcaaga cgtgcgtaaa caccgatgat acgtccgcgt
     3061 gagtatgcat ctggaagacc agttacagtg tgtgcgtgac gagcgcgacg aatatttgaa
     3121 gtgtaggcac ggaaaatacc gtcgttaact gttgttacat atttagtgaa gatttcgtga
     3181 acagctgggt ctggttcgta tccattttct ttcaaagtag tttcagccat acggatacca
     3241 ccttttggca tgaagttcaa tttgaagagt tcatcgtttt ggataccgaa gataacttca
     3301 ttttctttgt cgataaatcc agcagggata tcagcgatag atgttggacg agtgtccatt
     3361 gggaaacgag tttcttcgta gtgtgcttta gtttcttcta caattttctt gatgtgaagt
     3421 gaacgctctg ttggtcctgc aaggaagctt tcgtctccat cataaggtgt gtagttagct
     3481 tgtacaaagc gtgatacact tgctttttct ttccaatcta cgcctttgaa gccttcccaa
     3541 gctttgtcaa aaatatcttg tgcttcaaca actgtcttaa caaccatatt aatgtcctct
     3601 tttttctagt aacagtcatc tgttacattc atgagacaag tataccatat agtaaccgat
     3661 tttaacaagt gaaaaatccc tatttttaca ctttcttttc taaaacagtc tatattttat
     3721 ttcaaactgt attatatttt tgaaaaaata aagtcctttt ttcttttttt cagaaaaaag
     3781 ggtataataa aagaaaataa gcagtaacac tcaatggaaa tcgaaaagca aactaggaag
     3841 ctagccgcag gctgctcaaa gcactgcttt gaggttgtaa atagaactga cgaagtcagc
     3901 tcaaaatact gttttgaggt tgcagatgga agctgacgtg gtttgaagag attttcgaaa
     3961 agtataaaaa ggtgctaggc atgttgattt ttcctttgct aaatgatttg tcaagaaaaa
     4021 tcatccatat tgacatggat gccttttttg ctgcggtgga aatcaaggat aatcctaaac
     4081 tcagaggaaa acctgtcatt attggaagcg accctcggca aacaggtgga cggggagtcg
     4141 tttctacctg tagctatgag gctcgagctt ttggtgtcca ttctgccatg agttccaagg
     4201 aagcttatga acgttgtccc caggccgtct ttatctcagg aaattatgag aaatacaaag
     4261 ctgtgggact ccagattcga gctattttta agcgctatac agatttgatt gaacccatga
     4321 gcattgacga agcctatttg gatgtgacag aaaataaact cggtatcaag tcagcggtca
     4381 aaattgctcg cctcattcaa aaagatatct ggcaagaact ccatctaact gcttctgccg
     4441 gtatttccta taacaagttc ttagctaaaa tggcgagtga ttatcaaaaa ccacatggtt
     4501 tgacagtgat tctacctgaa caggctgagg attttctcaa acaaatggat atttccaaat
     4561 ttcatggagt aggaaaaaag acagtagaac gtcttcatca aatgggcgtt tttactggtg
     4621 ctgatttact tgaagttcct gaggtaaccc taatagaccg ttttggtaga ctaggctatg
     4681 atctgtatcg aaaggctcgt ggcattcaca actctccagt caaatccaat cgcatccgta
     4741 aatcaatcgg caaggagaaa acctacggga agattctcct tgctgaggaa gatatcaaaa
     4801 aagagctgac tcttctatca gaaaaagtcg ctctcaatct acatcaacaa gaaaaagctg
     4861 gaaaaattgt cattttgaaa atccgctacg aggacttttc aactcttacc aaacgaaaaa
     4921 gtcttgctca aaaaacacaa gatgctagtc agataagcca aatagccctg caactctatg
     4981 aagaattaag caagaaagaa agaggtgtcc gcctattggg gattaccatg actggatttt
     5041 aaagctcaat gaaaatcaaa gagcaaacta ggaggctagc cgcaggctgc tcaaaacact
     5101 gttttgaggt tgcagataaa gctgacgcgg tttgaagaga ttttcgaaga gtataaaacc
     5161 ttgaagagtt gccccttcaa ggtttttctt atacaaataa acggacaaaa ctgtaaagta
     5221 gcaaaacact accaagcacg atacggtatt taccaaaaag ggtgaagtcg tgttttttca
     5281 catagctggt caagaagcga atagccacca tgctgaccgc aaaagctact cccatcgcga
     5341 ccaagagcaa aaacaattgc ccaaagctca agagttctcc ggctttcaca aatttgaaaa
     5401 tctttaaggc actagctcca aacataacag gaatcccaag atagaaggta aattctgtca
     5461 caactgaacg actggttcca tttaacaaac caccgacaat cgttgcacct gaacggctag
     5521 tccctggtaa aagagcaaga acttggaaga gtccgatata gaaagcggtc gtataaggaa
     5581 gcttgtccaa ctctgttaca cttggctcga tagcacgcgc tttattgcgc ttttccaaat
     5641 agatgaaggc aaccccgtag ataatcaaca tgagagcaac tgaaaccatg ttatggaagt
     5701 gggtatcaaa ccaatcatca aatttaaaga caccaagtaa aggtaaagta gcaatcaaga
     5761 ccttcaacca tagtctccaa gtcttacgaa cttcctgttt gtccttagtc ggtttaaaag
     5821 gattgagctt gttaaaataa atcaccataa ctgctaaaat agcaccaagc tgaatcacga
     5881 cattaaacat ggacataaag gcttcatttt gattttggta ttggatgaat tcctctgcta
     5941 aaatcaagtg acctgtactg gaaatcggca accattccgt aattccttca acaatcccga
     6001 agaagataga ttttaaaatt tcaataagat acatagatta ctccctatat tataattagc
     6061 gcagttagct actgccaaag cccaagtggt atacttggaa taagccactg tggattagtt
     6121 catttcctcc aatcgcttga cgatttccga aaggatctaa ccacagcttt tgtttcaatt
     6181 ggtaatgagt ttgataacgc atagacgttt tatctcgtct aaggtaacaa ggcaaaaagt
     6241 tcgtggataa ccaagtagac ttgaaatact atatctggag gtactcccat gctttatgtg
     6301 ggcattgata tcgctaaaaa taaacacgat gttacagcct tgaatgttcc aggaaaaact
     6361 gttcttaaac cactcacttt ttcaaataat aaagctggtt ttgaactctt agatctgtct
     6421 cttcgacagc tcaaccaaga ctgtctcatc gctcttaaac ttctttctga tcccaatcgt
     6481 gaacaatttc aacacgataa tcggcaagta gacctaaaaa tactggctag acatattcat
     6541 cgtctcaaga aaaaacagtc tgattggaaa gtacaataca ctcgttgtct tgatatcatc
     6601 tttcctgagt tggataaaat cgttggaaag cattcagaat atacctacca actcttgacg
     6661 cgctacccta atcctcagaa aaggattgag gcaggatttg ataagctgat agaaattaag
     6721 cgattgaccg cttctaaaat tcaggatatc ctctcagtcg cacctcgttc tatcgaaaca
     6781 acatctcctg ctcgtgaatt cgaaatcatc gaaatcatca aacattacaa gaggctcatt
     6841 gacaaggcgg aaacatgtgt caatgacttg atggctgagt tcaactcagt catcacgacg
     6901 gttactggga ttgggggtcg tttaggggcg gtcattttag ccgagattcg aaatattcat
     6961 gcctttgata atcctgctca attacaagct ttcgctggac tggattcttc tatttatcag
     7021 tcaggtcaga ttgatttagc tggaagaatg atcaaacggg gttcccctca tctgcggtgg
     7081 gcactcatac aagctgccaa agtatgcgct cgcttttcac ctgcttttaa ggcctatctt
     7141 aagactaagt tagaacaagg aaaacattac aatgtagcca tcatccacct tgcaaaaaaa
     7201 cttatccgaa ccctgtttta tatcctaaaa aagagctgcc atttgacgaa caaaaagtga
     7261 tgtaatttct gaaattaaca caggattacc tttgaaaaaa tggacttttt caagggcttt
     7321 ttgccgtgct ctaaaatcat cgccaaatca tcaaattgaa ataagaaata gtttagataa
     7381 aactattgac ttttcttata gtttgtcttt cttctatctt ccattatatc atactttttc
     7441 agtctatggt agctctcttt aaaaggctcc gatactgccg ccacctccgc ctccagagaa
     7501 gccaccgcca gaacttccac ttccagaaga tacggagtag gtacttgctg tatttgcgac
     7561 actagcataa tggctcattt gcgcgcttga atgataaaac atactgtgcc agccataagc
     7621 tacatagaga ttgatatctg gattttcaac ttgaatctga tgaaccttca tcaaatgact
     7681 aaccttgtcc gcatagccaa ataaggttgc atagaccaag agacgattcc aaacaacaat
     7741 actttccaat tcagccttat ccagtcgtgc aatctcacgt aacatatttt caaaactggt
     7801 ccagagatag tagacctcag ctcccgcttc atttagaaca ccatcacgat tatctagtcg
     7861 aagcttccaa taatagaaaa cagacaaaac taaccctaga aaaccaagta ttggcaaagg
     7921 gaggtaaaga tagccatgaa cgtctaaact gtacaagaac aaaccaaatc cgataaatag
     7981 gggcaagata gtcaagacac ccatacccac ttgcaaagtc ttttccaaac cagttaaagg
     8041 acgatagtaa tctgggagcc cccagaagga aactcgtttt ctcactcctt cttgcatctg
     8101 gttcaatacc tcttcaaaag aagatttgag ttgaagccct cttgcttgaa tccgtttttc
     8161 atcagaaact ttggctctac gataaagact atcagatacc ttgtaatccg caaaaaaatt
     8221 ggaaagagtg gcttcttttt tgcctgaaaa ggctagattt agacagtctc tctcaaatct
     8281 tgacaaacca tcttctttca ccaatctcaa gccaactgca tctccttctg aaataataga
     8341 gacattccca cggtctatca catctagcaa ggtagcttga ataagttggt caaaagtgaa
     8401 tttgccagcc cccttgacca agggactcac ttcctccaag gaggtcgagt agactgcttc
     8461 tgataaaacc ataggctcta attccattgg tggttcatag agacgatgat ttttggcata
     8521 tttgactgaa ggagtggtct ttcttctata aataaaatag aagcagacac tcaataacaa
     8581 ggagatagaa agtatcgaag ggaggaccca agtaacgagt tgtttactct gatctttttc
     8641 tctaacaatc gagtcttcta tcttattaaa ctcttctaaa cgattccctt tcaagccctg
     8701 atccctagcg ctagcaaaat cggtccgaga ccaataggca tgcaactcaa ctccacgctt
     8761 agccggaaga ttgtctaaac ggatagtata atcaaggtta ctcttttcaa tcgttccctc
     8821 tctaaaaagt ttccctgtat ggaaaaagag tttctcagcc cccttgtctc cccttacatg
     8881 aaattcaaac ttttcaatag actctgaact atctgtcaga ggttgccaat ttaattcagc
     8941 gatatcatca taaaggaaaa gtaaattttt taagttccag acgaggtcaa cttcaactat
     9001 gtcgccctcc tgacctggat tatagactct cacagtataa ccatccgctt cttctgttac
     9061 ttcgctagtc acatctgcta gttctgcacc gtttttcgca gcctgaacct ttggatgagg
     9121 gtcaatgtca aacccgctag gcatcttacc agcacgtcca agtcccacga tttggccctt
     9181 aaagtcctcc tcaaactggt aaactatctt ctgtctaaac tctgccgtat tatctgcatg
     9241 aatatacaaa tccccttgat aagagtttat cttgaaatca atggcaaaaa cagagagtgg
     9301 aagaaggcaa aacaagccta acaccagtaa gaaaaaagtt tttttcatca actaagcccc
     9361 ctttttatct ttcttatcat tatagcatct tttcgtaagt aaaggcttac ttatgttgaa
     9421 aaattacgca tttttcgata aaataggaga cagttatttt ttaatagatc agaataggag
     9481 aaatcatgag aaaaatatac ctatctattt tcacaagtct cttgctgatg ctaggacttg
     9541 tcaatgttgc tcaagccgat gaatatttac gcatcgggat ggaagcagca tatgctccct
     9601 ttaactggac ccaggatgat gatagcaacg gagctgtcaa aatcgatggg accaatcagt
     9661 atgccaacgg atacgatgtt caaatcgcca agaaaatcgc taaggactta ggtaaagaac
     9721 ctttggttgt taaaaccaag tgggaaggtc tagtccctgc ccttacttct ggtaagattg
     9781 acatgattat cgcaggtatg agtccaactg cagaacgcaa acaagaaatt gccttttcga
     9841 gcagttacta cactagcgaa ccagttttgc ttgtcaaaaa agattctgcc tacgcaagtg
     9901 ctaaatcttt ggatgacttt aatggtgcga aaatcacttc tcaacaaggt gtctacctct
     9961 acgacttgat tgcacaaatc ccaggtgcta aaaaagaaac agccatggga gacttcgctc
    10021 aaatgcgcca agctcttgag gctggtgtca ttgatgctta tgtttctgaa cgtccagaag
    10081 cactgactgc tgaagctgcg aactctaagt tcaagatgat tcaagtagaa cctggtttca
    10141 aaactgggga agaagataca gctatcgcta tcgggcttcg taaaaatgac aatcgtatta
    10201 gccaaatcaa tgccagcatt gaaaccattt caaaagatga ccaagttgcc ttgatggatc
    10261 gtatgatcaa ggaacaacct gccgaagcta caacaactga agagactagc agtagtttct
    10321 ttagccaagt cgctaaaatt ctttctgaaa actggcaaca actcttgcgt ggtgctggta
    10381 tcactctttt aatctctatc gtcggaacca tcataggtct cattattgga cttgccattg
    10441 gtgtcttccg tactgctcct ctctctgaaa acaaagccat ttatggcctt caaaaactag
    10501 tcggctgggt tctcaatgtc tacattgaaa ttttccgtgg tacgccaatg attgttcaat
    10561 cgatggttat ctactatgga actgcccaag ctttcgggat caaccttgac cgtacactgg
    10621 ctgctatctt catcgtttca atcaataccg gtgcctacat gactgaaatc gtccgtggtg
    10681 gtatcctagc agttgacaag ggacaatttg aagctgcgac tgctcttggt atgacccata
    10741 accagaccat gcgtaagatt gtcctacctc aggtagtccg taacatccta cctgcaactg
    10801 gtaatgaatt tgtcatcaat atcaaagata catctgtatt gaacgttatc tctgttgtcg
    10861 aactttattt ctcaggaaat accgtggcaa cacaaaccta tcaatacttc cagacattta
    10921 caatcatcgc cgtgatttac tttgtcctca ccttcaccgt aacacgtatc ctacgattta
    10981 tcgagcgccg aatggacatg gatacctata ctacaggtgc taaccaaatg caaacggagg
    11041 atttgaaata atgacacaag caatccttga aattaaacac ctcaaaaaat cctatggaca
    11101 aaacgaagtg ctaaaagaca tttcactcac tgtccacaag ggagaggtca tctctatcat
    11161 cggaagctct ggaagcggaa aatcgacctt cctacgctcc attaacctac ttgaaacacc
    11221 aactgatgga caaatccttt atcatggaca aaacgtcctc gaaaaaggct atgacctcac
    11281 gcaataccgt gaaaagttgg ggatggtttt ccaatccttt aacctctttg aaaatctcaa
    11341 tgttcttgaa aacacaatcg tcgctcagac aactgtccta aaacgcgaac gcacagaagc
    11401 tgaaaagatt gccaaagaaa acctggaaaa ggtcggcatg ggagaacgct actggcaagc
    11461 caaaccaaaa caactctcag gtggtcaaaa acaacgtgtg gccatcgctc gtgccctctc
    11521 catgaatccg gacgctattc tctttgatga accaacatca gctctcgatc cagaaatggt
    11581 tggagaagtc ctcaaaatca tgcaggacct ggctcaggaa ggcttgacca tgattgtcgt
    11641 aacccatgaa atggaatttg cccgtgatgt ctctcaccgt gttatcttta tggataaggg
    11701 cgtgatcgct gaagaaggta aaccagaaga cctcttcacc aatcctaaag aagaccgaac
    11761 aaaagagttc cttcaacgct atctcaaata aaaagaaaag gctgcatcaa ccgtgcagtc
    11821 tttttgctgt cctcaaaatg aaaaggcaga ttctctatct ctactacttg aaggtcaaga
    11881 atccgccgtt atccaaagat taatcttcaa atttttcata atttttttca tagaaatcaa
    11941 ttaagcctag ggctgtttca aatgaaatat tttttacttt tgcacgaccc tgcgccagag
    12001 caatgataga catttcacgc gcattcgttt ctttagagat acggtagcct gtgattttct
    12061 tatcacgaac ccagccaaca actgattcta ctttttcaaa gtttgactta gccatgtttt
    12121 tctcctattt tcttctttat aatatttaat tgtatacgtt tttactactt ttgtcaataa
    12181 aaaaaacata tattcaacga aaataattag ttcagaattt tcttacttcc tttttaaatc
    12241 cgataatata taggttttgc tagcctctac accataaata tttgctaata aaactactgt
    12301 attattaccc tcttaaggtg cgaaattatt caagttctta aaaaatgctt ctctatttcc
    12361 gtaagatagc ttatttcttc gatttaagaa ctgaagatga tagttctaac ctttagaaat
    12421 ccaagccttc actagctcaa aaactcctat ctttcttcct caataaatca tctgagagat
    12481 aggtatttct tatatccttc aaattcatca ctcctttgga tattgaggtg ctagcctaga
    12541 agcagacacc cgattatcta aaccatcctt aatagagatg acaagacaga taagctcagt
    12601 taattactta tatatctttt taatatggta tatttgtcaa caaaaagaaa tcaaatcata
    12661 ccttatactc aatgaaaatc aaagagcaaa ctaggaagct agccgcaagt tgctcaaaac
    12721 actgttttga ggttgcagat agagctaacg tggtttgaag agattttcga agagtattaa
    12781 agacagtgtg actatgcttg tcaatagata ggaaatcaaa atgaaggatg gaaatctgag
    12841 ccaaacatca taagtgctat aatgaacaga agtaagaatt gcacgataag ttttctaaaa
    12901 ccataggaat cgtccccttt cttcatcttc attatagcat atatacatca gttgtacaaa
    12961 taatatgata tttttttatt agtcctcaga caagcatatt ataaagcgtt tcattaccat
    13021 ttaagttaat ataagctgga tcaaaacctt ccattctacg aatcaaacct gcataatcat
    13081 gcttatctgc taaagcgatc ccaatcaata ctgggcctgt tcccttgcta gctcgtttga
    13141 tatactcaaa acgtgtgata tcatcatttg gccccaggat atcatttaca aactcacgca
    13201 aagctcctgg acgttgtggg aaattgacca caaaataatg tttgatacca tcataaatca
    13261 aggcacgctc ttccatttct ggcatacggt tgatatcatt atttcctcca gaaatgatac
    13321 aacaaatggt tttcccctta atatattcag ctaaaacctc taaagaggcg atactagctg
    13381 ctccagcagg ttctgcgact atcccttgct tagagtaaag gtcaatcaag gtttcagaaa
    13441 tcaatccctc atcgacacct accaaagttt gaatatgttg acgagttgct tcataggtca
    13501 actgacctac cttttgcaca gcaatcccat ccgcaaattt atcaatttcc ttgagtttga
    13561 ctggacctcc agcctcaaag gcagctttca tggaacgcgc tccattcgcc tctactccga
    13621 taacctcaat ctctggactt gtttccttga tataggtaga aaccccggca atgagaccgc
    13681 caccaccaac aggaaccaag acagcatcaa aatcaatcga ttcttttcga gcttcttcta
    13741 aaatctcata agcaactgtt ccttgacctg cttgaacatg agcatcatca aaaggatcaa
    13801 taaaggtacg attttcagag actgtaaatt cttgagctgc tttggctgag gcatcaaagg
    13861 tatctccaac tagtttaata gttacaaaat ccccaccaaa aaagcgaacc tgaccaatct
    13921 tttgttgtgg cgtagtaatg ggcataaaga tagtagcagg aattttcatt tcattacaag
    13981 tataggctac tccctgcgca tgatttcccg cagaagcgca aactacccca cgttcacgtt
    14041 cttccttgct gagctgggaa atggcataat aggcaccacg aattttaaag gagcgaacac
    14101 gctgggcatt ttcttttttc aaataaatct tagcaccata cttctccgat aaataatgat
    14161 cgtaatccag tggagtattc acaaccacac cgttcaagac cttgtgagcc ttgattatat
    14221 cttttgaact taacatataa aacctctttt tctataaaaa acagtcacta atgactgttt
    14281 tttagttatt catctccgaa aatttcagta acactttcat ggtatttatg agccatacga
    14341 atcgaaaact ctttaggaag ttcataacga tttgtggaaa tccaatcata taaccattct
    14401 accaaacttt cttcactatc attacgatgg aagataaaat agtttaaaat ttctttatat
    14461 tctacatcat tcaaatccaa cgtgtctaca aattgactac gaggaacaaa attagaatct
    14521 aattttctta gttgatctgt caattctccc aattgtaaat ccaactgaaa aaatagtttt
    14581 tgcagttgcc tatcagtttc atcacatcct gtcttgatag aaaacaaatt ggtaatattc
    14641 atatgatttc aacccctaaa taagtacatc taatatccca cgaatagctg aagctaaagt
    14701 tttcgcagtc cagtcattta aacccgattc tttcaatcca gatgcaataa tttgctctat
    14761 ttgatataaa ccgccatcta tcgtctcatt tattctgcga agaggacctt caatatagga
    14821 taaagcttct ccgaatctaa cagctgattt aggtcctaat gatttaccaa ctatatttgt
    14881 taatattttt tatttctcaa aatccatttc gctatataac gagcagattt agtcgcacca
    14941 gctctctcaa acggagaatg aatttcaaga ccttcttctc tagctatttg tgccaatttg
    15001 aagaattgtt caaaggtcat atgcaaccta ccatcttcaa aattagcatc atcataaatg
    15061 ttaattacag cattttcatc atacgaccaa tctgctttat tttggtctgc tagcactatt
    15121 accgacggtg taattacatt atacaactag aaccaataat aacgatgcaa tttttctcat
    15181 aatctttttc ataaaatcat ctccagcgct atatatttct aattagttat agattttgaa
    15241 tgcatcatcg tcgtttttac caacgaatgg cattgcttta cgcaattctg caccaacttt
    15301 ttcaatttca aggttagctg cttgttcacg gtaagcagtc aattttggac gtccagcttt
    15361 atagtcattt acaaagtcat ttgcaaattt accattttgg atgtctgcca agacagcctt
    15421 catattttct ttaacttgtt cagtgattac acgtggacct gatacatagt caccgtattc
    15481 agcagtgttt gaaatagatt gacgcatttt cttgaatcca ccttcgtaga tcaagtcaac
    15541 gatcaatttc atttcgtgaa gaacttcaaa gtaagccaat tctggagcgt aacctgcttc
    15601 tgtcaagact tcgaaacctg cttcgataag ggcagtcaaa ccaccacaaa gtacagcttg
    15661 ttcaccaaac aaatcttctt cagtttcttc tttgtaagtt gtttcaagaa gacctacacg
    15721 agccgctcca acacctttac accagtccat agcaatgttt ttagcatttc ctgttgcatc
    15781 ttggtatact gcataaagag ctggaacacc aaatccttct tcgtaagtac gacgtaccaa
    15841 gtgtcctggt cctttaggag cacacatgaa gacatctaca tccgcaggaa ctttgataaa
    15901 ttcaaagtgg atgttgaaac catgggcaaa tccaactgcg tttccagctt ccaagtttgg
    15961 agcgatttct gcttcgtaca attcttgttg aatttcgtct ggcgccaaga tcatgataac
    16021 atcagccaac ttagtagctt ctgctactgt gtaagtatca aatccatctt cttttgcttt
    16081 atcaaaagat ttacctggac gtacaccgat aataacgtca cgacctgaat cacgcaagtt
    16141 ttgagcatgc gcatgccctt gtgaaccata accgataacg gcgatttttt taccgtcaag
    16201 tgctgctact ttaacatctt tttcatattc catttgaact gtcatagctt ttctctcttt
    16261 tctattattt attgcctttt aagctggttt aacaaattta agttggattt ttaatcgcgg
    16321 gtaaatccag ttgcacccgt tcgagcaata ttgcgaatac cgtatgggcg aatgactcgc
    16381 aatagggctt cgctcttttc tgcatttccc gtcatctgaa tggtaatcga gcttggcgct
    16441 acgtctacca ctgttgcacg gaaaggttga ataatcgcta aaatctcagc tctcttctca
    16501 gctggcgctg acatcttaac caaaatcacc tcgcgctcca aatgaggctt gtctgtaata
    16561 tctcgaatgc gaatcacatc aatctgacga ttgagctgtt tgatgatttg ctccacttca
    16621 tcatgagaag caacatcaat aataatagtg atacgcgata cattcggatc ttctgttgct
    16681 ccaacagaga tgctttcaat attaacctga cgacgagata ggacacctgt aaagcgattg
    16741 aggactcctg aacgattttg tagttttgct gttaacattc tacgcatgga actgcacccc
    16801 caacatctca tgattactct taccagccgg taccattggt aacacctgtt ccttacgaga
    16861 aatatctacc tcaattagca taggaacatc ctcagtgatg acttcaaggt cttgagccaa
    16921 ggtctcagga ttgtcaaact tatagttttt aataccataa gcctgcgcca tcaattggaa
    16981 atcaggaagg gtatcaaaga ccgactctga tgttctgcct tcatagaagg attcctgcca
    17041 ctggcgaacc attccgagtg aatgattgtt cagcataacc accttgattg gcaccttgta
    17101 aatattcaaa atagccaact cctggttggt catttggaaa ccaccatccc caacaaacaa
    17161 gactacttcc ttatctgggt tagcaatttt agcaccgatt gctgctggaa ttccaaagcc
    17221 cattgttccc aaaccacctg aagtcactaa ctgacgttca ttttggtagg gataatactg
    17281 agctgtccac atttggtgtt gaccaacgtc tgttaccaca atggcatctc cattcgtcaa
    17341 ttcaccaatt cgttcaataa ctgcttgcgg ttgaaccaca cgctctttct tgtcatacga
    17401 acgaacacga ttcttgtctt tagtgacttt ctcaatccac ttttcagtat tgttgtgaac
    17461 tgttggttct gctagcaaca tttgcaaggc cttcttagca tctccaacta caggaatgtc
    17521 tgcactgata atcttgccaa tctcagctgg gtcaatatca atgtgggcaa ccttagcatt
    17581 cttagcgaaa gtcttaggat tccccgtcaa acggtcatcg aaacgagaac caatactaat
    17641 cataaagtcc gcttccgtca tggcaatatt tgctgcgaat gacccgtgca tgcctcccat
    17701 tccaagaaag agtgggtgac tcgttgcaat cgttccttgt cccaaaagac tggttaccac
    17761 tggaatttga tagcgttctg caaattcatt tagttccgta gcagcctcag cataactaat
    17821 tccaccacca gctaacaaga ctggcttttt agccttggac aattgcttca agattttctt
    17881 gatttgcata tcattcggct caagagtcgg ctgataactt ggtaaattca cttctggtga
    17941 ataaatgaag tctgtttcta aagcagatat gtcttttggt aggtcaatta caactggccc
    18001 tggacggcct gtagttgcga tatggacagc ttccgtaatg atacgcggaa tatcagctgt
    18061 ctcacgaact tggtaattgt acttagtgat tggcatggta attcctacga tgtctgcctc
    18121 ctgaaaggca tccttcccaa tccctgctcg cgccacctga cctgtaaaga ccaaaagggg
    18181 aacgctatcg ctcatagcat ccgcaatccc tgtaatggca tttgttgctc ctggtccact
    18241 agtgacgacg gcaacaccca actttccagt tgatttggca tagccttcag cttcatgcaa
    18301 acaaccttgc tcatggcgcc ctagaatgtg gcgaatgcct ttaaaattat atatcgcatc
    18361 ataaaaaggc aaaaccgcac caccaggata accaaagatg gtatcaactc ctaaatcacg
    18421 aagtgtttcc aaaactaggt ccgaccccgt cttaggagat tctaaactga ttttctccat
    18481 tattcccctt tctttcctct taaaaataac ttgttactat cataccattt tttcaaaatt
    18541 tttcaagata aaagaagaaa ttttctgaat tttctatttt aacgtttatt tatgaatgtt
    18601 atttttgttt ttattaaaaa gataccgatt tcatttacta aaaagaaaaa agaactgatt
    18661 tctcagtcct tcattaatct tattccacac taaataggta tgggtaaaca ggttgttgac
    18721 cttggtgaat ctcgacttca acgtcttcga attcttctac gatttcttga gcgatttcat
    18781 tggcaagttc ttcgcttccg tcttcaccga catagaaggt tacgatttca ctgtcttcat
    18841 ccaacatatg tttcaaggtt tcagtcaatg tttggtgcat atcagggttt gacacaagaa
    18901 tttttccatc caccatacct aaattatcgt tttcatggat ttctaagcca tcgatcgttg
    18961 tatcacgcac ggctgttgtg acgcttccgc taacgacatc gctaagagca gctgtcatac
    19021 gctcttggtt ttcttcaatg gacttgcttg gatcaaaggc aagaagactt gtcatacctt
    19081 gaggaagagt gcgagcctct accactaccg ctggttgctc caaaacttct gccgcagatt
    19141 gagctgccat gaagatgttc ttgttgtttg gcaagaagat gatgttacgg gcattaacct
    19201 gttcaacagc cttgataaag tcttctgttg aagggttcat ggtttgaccg ccttcgataa
    19261 cataatccac gccttgagaa cagaagatat ctgctagacc tttaccagcc accacagcaa
    19321 tcaaagcata ctctttttct tcagccgact tgataacttg agtagcttct ttctcaacct
    19381 gtgcttcgtg ttggttacgc atattgtcaa cttttacctt gaccaagcta ccatatttga
    19441 gaccttcttg cataacaagt cctggatctt ctgtatgaac atggactttg acaatttcat
    19501 catcgttaac aacgaggaga gaatctccaa gctcatccaa gtagttacgg aattcatcgt
    19561 agtcaaaatc tttagcatag gttggacctt gcttaagagc taccatgatt tcagtacagt
    19621 aaccaaacgt gatgtcctca gtcgctacgt gaccagctac agacttatga tgctctacat
    19681 tgatcatctc actcatgttg gcaggagtcg ctacaaagtc ctcagatgca atatattcgc
    19741 cagtaagggc tgaaaggaaa ccttcgtaga tgaagaccaa tccttgacca cctgagtcca
    19801 caacgccaac ttctttcaat actggaagca tgtctggtgt tttagctaga gctgttttag
    19861 caccttccaa ggctgcgcgc atgacttcaa cagtgtcatc tgtttgctca gcttttttct
    19921 tagcaccgat agcagctcca cgagaaactg tcaaaatcgt tccttcaaca ggtttcatca
    19981 ctgccttata ggcaacttcc acacctgatt ggaaggccag agccaagtct tgacctgtta
    20041 actcgtcttt atccttgata gcttgggaaa atccacggaa aagctgagac gtaatcactc
    20101 ctgagttccc acgcgcaccc atcaaaagcc ctttggcaag aatgctcgct acttctccaa
    20161 ctgtagaagc tggcttgtct gcaacttctt tagcaccatt ttcaatggtc attcccatat
    20221 ttgtcccagt atctccatct ggaactggaa agacgtttaa tgaattgaca tattcagctt
    20281 gcttattcaa gcgagttgat gcagcctgca ccatttcttg aaataagcta gtagtaattt
    20341 ttgacacggt tattctccta caactttgat attttgaatg tagacattta cagtctgagc
    20401 agtaattcca agctggtttt ccaagctaaa ggcaacacgc tcttgaatgt tttttgacac
    20461 ttcactaatc tttgttccgt agcttaacac ggtatataca tcaactgcaa tactgccatc
    20521 ttcggctgcc tttacgacga cacctttaga ataattttcc ttacctagca gggcttggaa
    20581 attatctttg agggcatttt tactagccat accgaccaca ccaaaaatct cagttgctgc
    20641 tccacctacg acggttgcaa tcacttcatc tgttagttcg atttgaccat cttttgtatt
    20701 aatttttaca gtcatccttt ttacctcaac tagttgatac tctattttat catatttcag
    20761 cccaagtgta aaagcagaat gatgtatcag cggatattta ctctattttt caaacgatgt
    20821 tatacccaca ataaaagaaa aaagacccta aggtctcctt tgcttttatt attaaacgcg
    20881 ttcaacttta cctgatttca aagcacgagc tgaagcccaa acttttttag gtttaccatc
    20941 gataagaaca gtaacttttt gaaggtttgg ttttacggca cgttttgttt ggttcatcgc
    21001 gtgtgaacgg ttgtttcctg atacagtctt acgacctgta aagtaacata ctttagccat
    21061 tgtgttttcc tcctattaga tctaatatag cggatgtgct agcaccacat accgtactat
    21121 gttatcacac tttcttgttt tttgcaaggg aattggaaga ttttttattt gtgtcttaaa
    21181 tcaggtcttg cgtgacattt tctgctctcc acatgccatt gttgattaac agaacaccag
    21241 aattaaaatt atgtgtataa aaatcatctc taactgcagc taagggtata gccgtcaagt
    21301 ccaaatccca cagctcatct atcgattttc ttacaacaat atctgaatcc aaatacagta
    21361 cacgagactc gcttacatac tttggaataa aatacctaaa aaaagccgca tatgaaagtc
    21421 cctcaaaggg gagacgataa cctttcagaa tactactgtc aatctgaaca ttcacaatct
    21481 cactattcaa agtctctagt cttttttcca tcaattggaa ccattctcgc ggaaggtcat
    21541 cattaaaaac ataaaactta agattataat gatgaacaca aagagatttt attgttgttt
    21601 caactttatc catataagca ttatctgcac ctaagacaat cgcttttttc tcttctttca
    21661 ctctttatct tatttctttt tattcccatc atattattcc catcatatgt ttctacgtaa
    21721 ccattatttt cgcctattcg ttcgtaaaac cataccagtg gagattttag atgaagtccc
    21781 attacggttt acaattttta cattacgaca cggagtttta caaatcgatt tcatttgcca
    21841 aacgtagtta gtgaggcagt tagctagttc gccaaatagc gactagcgtc caacaatttg
    21901 gaactttagc tccaattgtt ggtactgagt cacatcttct cctctaactc tacgtctgga
    21961 tacttgtccg caaaccagcg gagggcaaag tcattttcaa agagaaagac tggttggtca
    22021 aaacggtctt tggctaagat attgcgactt gacgacatcc gttcatccaa gtcctcaggc
    22081 ttgatccaac gaacggtctt tttacccatt gggctcatga ccacttccgc attgtattcg
    22141 ccttccatac ggtgtttaaa gacttcaaac tggagttgac caacagctcc cagcatgtac
    22201 tcacctgttt ggtaattctt ataaagctga acggctcctt cttgcaccaa ttgctcaatc
    22261 cccttgtgga aggatttttg cttcataaca ttcttggcag aaactttcat gaaaatttca
    22321 ggagtaaagg ttggcagtgg ttcaaattca aacttgtttt ttccaaccgt caaggtatcc
    22381 ccaacctgat aagtaccggt atcgtaaacc ccgataatat cacctgccac ggcattgatc
    22441 acattctcac gactttccgc cataaactgg gtaacattag atagtttagc ccccttacca
    22501 gtacgaggga gattgacact catgccgcgc tcaaattcgc ctgatacgat acggacaaag
    22561 gcaatacggt cacggtgacg aggatccatg ttggcttgga ttttaaagac aaagcctgag
    22621 aaatccttgt cataaggatc cacaatttca ccgtctgttt tcttgtgacc atgtggttct
    22681 ggagcaaact tgaggaagat ttcaaggaag gtctgcacac caaagtttgt cagggctgaa
    22741 ccgaaaaaga caggcgtcaa ttctccagcc agaatagctt cctctgaaaa ctcattccca
    22801 gcttcattta aaagctcaat gtcatccttg acttgctcgt agaaaggatt gctaccaaag
    22861 agtttgtccc cgtcttctag actggcaaaa cgctcatccc ctttgtaaag ctctaaacgt
    22921 tggttataga ggtcatacaa gccctcaaag gctttcccca tcccgatagg ccagttcata
    22981 gggtagctag caatgcccaa gatttcttcc aattcttgca agagatccaa aggctcacga
    23041 ccgtcacggt ccagcttgtt cataaaggta aaaactggaa tgccacgatg tttcacaacc
    23101 tcaaacaatt tcttggtttg agcctcgatc cccttggcag agtccacgac catgaccgca
    23161 gcatccaccg ccatcaaggt acgataggta tcttctgaga agtcctcgtg ccctggcgtg
    23221 tctaagatat tcacgcgctt gccgtcgtag tcaaattgca taacagatga agtaacagaa
    23281 atcccacgtt gcttctcgat atccatccag tcagatttag caaaagtccc tgttttcttc
    23341 ccttttaccg taccagcctc acgaatctca cccccaaagt agagtaactg ctcagtgatg
    23401 gttgttttcc ccgcgtccgg gtgggagata atggcaaagg tacgacgttt cttaatttct
    23461 tcttgaatat tcataagttc tctttctttg attctctatt tttcttgttt caatagctga
    23521 gaatgatttt tacattggat tttaccattc ctttcaatac tccattatat cggattttag
    23581 catttttttc aatttctatc tcttttcact tccccctccc ttatttatag gaaaatatgg
    23641 taaaatagaa cagactaaaa atcatcattt cacgaaagga tgcaagatga aaattacgca
    23701 agaagaggta acacacgttg ccaatctttc aaaattaaga ttctctgaag aagaaactgc
    23761 tgcctttgcg accaccttgt ctaagattgt tgacatggtt gaattgctgg gcgaagttga
    23821 cacaactggt gtcgcaccta ctacgactat ggctgaccgc aagactgtac tccgccctga
    23881 tgtggccgaa gaaggaacag accgtgatcg cttgtttaaa aacgtacctg aacaagacaa
    23941 ctactatatc aaggtgccag ctatcctaga cgatggagga gatgcctgat gacttttaac
    24001 aataaaacta ttgaagagtt gcacaatctc cttgtctcta aggaaatttc tgcaacagaa
    24061 ttgacccaag caacacttga aaatatcaag tctcgtgagg aagccctcaa ttcatttgtc
    24121 accatcgctg aggagcaagc tcttgttcaa gctaaagcca ttgatgaagc tggaattgat
    24181 gctgacaatg tcctttcagg aattccactt gctgttaagg ataacatctc tacagacggt
    24241 attctcacaa ctgctgcctc aaaaatgctc tacaactatg agccaatctt tgatgcgaca
    24301 gctgttgcca atgcaaaaac caagggcatg attgtcgttg gaaagaccaa catggacgaa
    24361 tttgctatgg gtggttcagg tgaaacttca cactacggag caactaaaaa cgcttggaac
    24421 cacagcaagg ttcctggtgg gtcatcaagt ggttctgccg cagctgtagc ctcaggacaa
    24481 gttcgcttgt cacttggttc tgatactggt ggttccatcc gccaacctgc tgccttcaac
    24541 ggaatcgttg gtctcaaacc aacctacgga acagtttcac gtttcggtct cattgccttt
    24601 ggtagctcat tagaccagat tggacctttt gctcctactg ttaaggaaaa tgccctcttg
    24661 ctcaacgcta ttgccagcga agatgctaaa gactctactt ctgctcctgt ccgcatcgcc
    24721 gactttactt caaaaatcgg ccaagacatc aagggtatga aaatcgcttt gcctaaggaa
    24781 tacctaggcg aaggaattga tccagaggtt aaggaaacaa tcttaaacgc ggccaaacac
    24841 tttgaaaaat tgggtgctat cgtcgaagaa gtcagccttc ctcactctaa atacggtgtt
    24901 gccgtttatt acatcatcgc ttcatcagaa gcttcatcaa acttgcaacg cttcgacggt
    24961 atccgttacg gctatcgcgc agaagatgca accaaccttg atgaaatcta tgtaaacagc
    25021 cgaagccaag gttttggtga agaggtaaaa cgtcgtatca tgctgggtac tttcagtctt
    25081 tcatcaggtt actatgatgc ctactacaaa aaggctggtc aagtccgtac cctcatcatt
    25141 caagatttcg aaaaagtctt cgcggattac gatttgattt tgggtccaac tgctccaagt
    25201 gttgcctatg acttggattc tctcaaccat gacccagttg ccatgtactt agccgaccta
    25261 ttgaccatac ctgtaaactt ggcaggactg cctggaattt cgattcctgc tggattctct
    25321 caaggtctac ctgtcggact ccaattgatt ggtcccaagt actctgagga aaccatttac
    25381 caagctgctg ctgcttttga agcaacaaca gactaccaca aacaacaacc cgtgattttt
    25441 ggaggtgaca actaatgaac tttgaaacag tcatcggact tgaagtccac gtagagctca
    25501 acaccaattc aaaaatcttc tcacctactt ctgcccactt tggaaatgac caaaatgcca
    25561 acactaacgt gattgactgg tctttcccag gagttctacc agttctcaat aaaggggttg
    25621 ttgatgccgg tatcaaggct gctcttgccc tcaacatgga catccacaaa aagatgcact
    25681 ttgaccgcaa gaactacttc tatcctgata accccaaagc ctaccaaatt tctcagtttg
    25741 atgaaccaat cggatataat ggctggattg aagtcaaact agaagacggt acgaccaaga
    25801 aaatcggtat cgaacgtgcc cacctagagg aagacgctgg taaaaacacc catggtacag
    25861 atggctactc ttatgttgac ctcaaccgcc aaggggttcc cttgattgag attgtatctg
    25921 aggcagatat gcgttctcct gaagaagcct atgcttatct gacagccctc aaggaagtta
    25981 tccagtacgc tggcatttct gacgttaaga tggaggaagg ttcgatgcgt gtggatgcca
    26041 acatctccct tcgtccttat ggtcaagaga aattcggtac caagactgaa ttgaagaacc
    26101 tcaactcctt ctcaaacgtt cgtaaaggtc ttgaatacga agtccaacgc caggctgaaa
    26161 ttcttcgctc aggtggtcaa atccgccaag aaacacgccg ttacgatgaa gcgaataaag
    26221 caaccatcct catgcgtgtc aaggaagggg ctgctgacta ccgctacttc ccagaaccag
    26281 acctacccct ctttgaaatt tctgacgagt ggattgagga aatgcggact gagttgccag
    26341 agtttccaaa agaacgtcgt gcgcgttatg tatctgacct tggtttatca gactacgatg
    26401 ctagtcagtt gactgctaat aaagtcactt ctgacttctt tgaaaaagct gttgccctag
    26461 gtggtgatgc caaacaagtc tctaactggc tccaagggga agtcgctcag ttcttgaatg
    26521 ctgaaggtaa aacactggaa caaatcgaat tgacaccaga aaacttggtt gaaatgattg
    26581 ccatcatcga agacggtact atttcatcta agattgccaa gaaagtcttt gtccatctag
    26641 ctaaaaatgg cggtggcgcg cgtgaatacg tggaaaaagc aggtatggtt caaatttcag
    26701 atccagctat cttgatccca atcatccacc aagtctttgc cgataacgaa gctgctgttg
    26761 ccgacttcaa gtcaggcaaa cgtaacgccg acaaagcctt tacaggattc cttatgaagg
    26821 caaccaaagg ccaagccaac ccacaagttg cccttaaact acttgcacag gaattggcga
    26881 agttgaaaga aaactagaca gaacaaaacc agccctaagg ttggtttttt cttctctacc
    26941 aactcccaat aactattttg gctttatttc cagagtattt tatggtaaaa tgaagagtaa
    27001 taatatttat taaagaggta aaaacatgat tgaagcaagt aaattaaaag ctggtatgac
    27061 ctttgaaaca gctgacggca aattgattcg cgttttggaa gctagtcacc acaaaccagg
    27121 taaaggaaac acgatcatgc gtatgaaatt gcgtgatgtc cgtactggtt ctacatttga
    27181 cacaagctac cgtccagagg aaaaatttga acaagctatt atcgagactg tcccagctca
    27241 atacttgtac aaaatggatg acacagcata cttcatgaat acagaaactt atgaccaata
    27301 cgaaatccct gtagtcaatg ttgaaaacga attgctttac atccttgaaa actctgatgt
    27361 gaaaatccaa ttctacggaa ctgaagtgat cggtgtcacc gttcctacta ctgttgagtt
    27421 gacagttgct gaaactcaac catctatcaa aggtgctact gttacaggtt ctggtaaacc
    27481 agcaacgatg gaaactggac ttgtcgtaaa cgttccagac ttcatcgaag caggacaaaa
    27541 actcgttatc aacactgcag aaggaactta cgtttctcgt gcctaatctc tagaaagagg
    27601 tcattctatg ggaattgaag aacaacttgg cgaaatcgtt atcgccccac gtgtacttga
    27661 aaaaatcatt gctatcgcta ctgcaaaggt agagggtgtt cactcttttt caaacagatc
    27721 agtgtctgat accctttcaa aactttcact cggccgtggc atttatctta aaaacgtgga
    27781 cgaagaactc acagcagata tctatctcta ccttgagtac ggagtaaaag ttcctaaggt
    27841 agcggttgct atccagaaag ctgtcaaaga tgccgtccgt aatatggctg atgtagaact
    27901 cgctgctatc aatattcacg ttgcaggtat cgtcccagat aaaacaccaa aaccagaatt
    27961 gaaagatcta tttgacgagg acttcctcaa tgactagtcc actattagaa tctagacgcc
    28021 aactccgtaa atgcgctttt caagctctca tgagccttga gttcggtacg gatgtcgaaa
    28081 ctgcttgtcg tttcgcctat actcatgatc gtgaagatac ggctgtacaa cttccagcct
    28141 ttttgataga cctcgtttct ggtgttcaag ctaaaaagga agaactagat aagcaaatca
    28201 ctcagcattt aaaagcaggt tggaccattg aacgcttaac gctcgtggag agaaacctcc
    28261 ttcgcttggg agtctttgaa atcacttcat ttgacactcc tcagctggtt gctgttaatg
    28321 aagctatcga gcttgcaaag gacttctccg atcaaaaatc tgcccgtttt atcaatggac
    28381 tgctcagcca gtttgtaaca gaagaacaat aaaaagaaaa agtgtttgat atctatcaaa
    28441 cactttttct ttgcctccca ctatctaaaa aaatgataat agatataatt gtaaacaaaa
    28501 atccagatag gttttgcatg attgagaaag ttaaaaaaac tatggcagag aatcgttaat
    28561 ctcagattgt cggtagaacg ataaacaagg gcaaaaaaga aaccaatcag actataatat
    28621 aataaactaa ttggatctct gtgagatagt atcaaatgac taagcccaaa gataaggcct
    28681 gataagatga catctaaata atacttggac tagggaaaga aggtattcat aaaataccct
    28741 ctatcaagag tctcctcaaa aacaggaccg atgattacag gcaggacaaa agataagata
    28801 gtcgataaaa aggttggttg tccatttgaa agaaccacgg taaaatactc atcatgaata
    28861 ttcctatgat taatcaaatg agcatagcgt gcccaaaaat taccgagaat ctgataaacc
    28921 acataagttg caaataagga gaagacaaat gaccagttcc agctcttttt cttttttaac
    28981 ctccaaatta atagaaaagg aaacttccca ctaatcccac tgttaaaata agagaataga
    29041 catcagctcc taaccctaaa atgatcgtca catacaatcc aattgtttgt ggtaaatagg
    29101 tagatagtaa aataataagc aaaaatattc caaattgtct tagtttcttt gtgtttctca
    29161 tcgtactttt ttgaaagatt accctgttcg gaagccgtac ttccaagcat ctatataaga
    29221 attaagtgcc ccttgcctca tatagggagc aaattctcta taatataacc atctactata
    29281 tccatcttcc caaacagcaa gaccacctga agtttgctcc aagtcctcag ttgaaataac
    29341 tgtaaatgtt tctgtacctg tcattgcaag taccttctta aaatagattg ttgtaggctc
    29401 acatttatag tatatttctt tttttgtcta ttttatagtc tatctcctca actggcaatt
    29461 tttcgacctg aattgcattt ttccataaaa aatgagacct ttctagtctc atttagtcat
    29521 tcttagtatt ttctaaatcg ttgatagcgt tcttccagca actcttctag cggtttttgt
    29581 gaaagtctag ccagctccgt ttggagttct tttttgacac tcttaattag ttctttacta
    29641 gaaagtccta cttcagaaat caccttatcc accacgtcca tttctaacag ttcatgcgaa
    29701 gtgattttca tcagttctgc tgcttccatg gcgcgagtac cgtccttcca taaaatggaa
    29761 gcaaagcctt ctggactgag aatggcatag atagaatttt ccagcatcca gacacggtcc
    29821 gcgacagcta gagccagagc cccgcctgaa ccaccttcac cgataataat ggcgataata
    29881 ggaactttca ggtcactcat ttccatgaga ttgcgagcga tagcttcccc ttgaccacgt
    29941 tcttccgctc cgacaccagg ataagcacct gctgtattga taaaggtcac aactggacgg
    30001 ccaaatttct cagcctgttt catcaaccgc agtgcctttc ggtagccttc tggatgtggt
    30061 tggccaaaat tccgtttgag gttgtcttgc aaactcttgc ctttttggat accaaccact
    30121 gttacagctt ggtctccaag ccaaccaata ccaccaacaa ctgcaccatc atcacgaaaa
    30181 gaacggtcac catgtaattg gataaattca tcaaaaatgc ctgtcgcaaa gtccaaggtt
    30241 gtcaagcgac tctgctcacg cgcttctctg actatttttg caatattcat ctaggactcc
    30301 ctccatgcaa tctgactagg ctagcaatcg tatctggtaa gtctcttctt ttgacaatag
    30361 catccacaaa gccatgttct aataggaatt ctgccttttg gaaatcctca ggcaagcttt
    30421 cacgaaccgt attttcaatc acacgacgcc cagcaaaacc aaccaagctc tgtggttcag
    30481 ccagaatgat atcgccttcc atagcgaaag aagctgtcac accaccagtc gttggatctg
    30541 tcaaaatggt caggtaaaag agaccagcat ttgaatggcg tttaaccgct gcagagatct
    30601 tagccatctg catgagactc atgattcctt cctgcatacg ggctccacca gaggctgtga
    30661 ataggacaac tggcaatttt tcgacagtcg catactcaaa caaacgagtg attttttcac
    30721 ctacaaccgt acccatagaa gccatgataa aattagaatc cataatccca agagccacag
    30781 tctgaccttt aataagagca gttcctgtca caacggcttc atgcagacct gttttttcac
    30841 gcatagatgc cagtttcttt tggtaaccag ggaaatgcaa gggatccttg ctttcaatcc
    30901 ctgtaaacaa ttctttgaag gttcccatat caatcgtcaa agccaagcgt tcttgggcag
    30961 aaatacgaaa ggtatagcta cagtgcggac agatacgttc acttcccaga tccttctgat
    31021 agatggtatg cttacagcct ggacactggg aaaataattc atctggaacc tctggcttag
    31081 cttgaggttt ttccctaacc gaacgattgg gattgattcg aatatactta tcttttttac
    31141 taaatagagc cattgattcc ccttttcggt ttaaactctt aaagtcattt tattcttttt
    31201 cttgatattt aggtaagaag gtttccatca agaaggaagt atcataatcc ccagcaatga
    31261 cattgcgatc tgaaatgaga tcaagctgga aatctgcatt ggtctgcact ccttcaatct
    31321 ctaattcata gagggcacgt tgcattttca tcaaggcgtc aaaacgattt tcgccgtgta
    31381 ctatgatttt ggcaatcata ctatcataat aaggcggaat ggtataacct ggataaactg
    31441 ctgaatccac gcgcaagcca actccaccac ttggcagata gagattagta atcttacctg
    31501 gacttggagc aaagttaaag gctgggtttt ctgcattgat acgacactcg atggcatgac
    31561 cgcgtaggac aatatcttct tgcttaacag acaaaggctg acctgccgca atgcaaatct
    31621 gttccttaac gatatcaaca cctgaaacaa actctgttac tggatgttct acctgaacac
    31681 gagtattcat ctccatgaaa tagaaatttc tacttgcttc atcaagaaga aattcaatgg
    31741 ttcctgcatt ctcatagcca acaaactctg ccgctcgaac agcagcagca cctatttcat
    31801 gacgcagcgt ttttccgatt gcaatcgagg gactttcttc caaaaccttt tggttattcc
    31861 tttgaagaga acaatcccgt tcacccaagt gaatcacatg tccatgctca tcacctagga
    31921 tttgaacctc aatgtgccga gctggataga taacccgttc tatgtacatg gcaccattgc
    31981 cataattggc cttggcctca ctagaggcag tttcaaaggc agaaacgagg tcatctggtt
    32041 tttcaacctt acgaatccct ttaccacctc cacctgctga agccttgagc ataacaggat
    32101 agccaatttt ttcagcaaca atcaaagctt cttcagagtt atgcacttct ccatctgaac
    32161 ctggtataac aggcacacct gctttaatca tctgagcacg cgcattgatc ttatccccca
    32221 tcatatccat aacatgacca gatggaccga taaacttgat acctacttct tcacacatgg
    32281 tcgcaaattt ggaattttca ctgagaaatc caaaaccagg gtgaatagct tctgcctcag
    32341 tcaagactgc agctgataga actgcattaa tattgagata agactctgtt gccttgccag
    32401 gaccaataca aactgcttca tctgccaaaa gcgtatgaag agcttcctta tcagcagttg
    32461 aataaaccgc taccgtcgca atccccaatt cacgtgccgc acggataata cgaaccgcaa
    32521 tttcaccacg attggcaatt aaaatttttc gaaacatgga gaacctcctt agttcccaat
    32581 tgcaaaagta aggataccac tggctgcaag cttgccatcc acttcagcct ttgcttcaac
    32641 cacagctatg gtgccacgac gttttacaaa agtcgctgtc ataaccaatt ggtcgcctgg
    32701 tacaacttgc ttcttgaact taaccttgtc cataccagcg taaaagacca gttttccttt
    32761 attttcaggt tttgataact ccaacacacc agcagtttgc gccaaggctt ccataatcag
    32821 aacacctggc ataactgggt attgaggaaa gtggccgtta aagaaaggtt cgttaatggt
    32881 cacatttttg atagcaacaa tggtatcctc gctcacttcc aagacacggt ccactagaag
    32941 cataggataa cggtggggaa gagcttcttt gattccttga atatcgatca tttgatacgt
    33001 accaatcctt taccaaactc aaccatttct tcgttagaga cgagaatttc cgttaccaca
    33061 ccatccttag gagctgggat ttcattcatg actttcatgg cttcgataat taccaatgtt
    33121 tgaccttttt tgacactatc accaactgta acgaaggcag gtttatctgg tccagcagcc
    33181 aagtaaacca ctccaacaag tggactctct acaagatttc cctcagtagc cacacttgct
    33241 tcagctggag ctggaacttc ttctgctaca gtctctgctg gagcagatgt aggagctact
    33301 ggactcggtg ttgctagaac gggtgctgga gcgacttgag ttgcaacttc aggcacaggt
    33361 cttgcttcat tcttgctaaa ctgcaactca tccgtcccat ttttataaga aaattctctc
    33421 aaacttgact ggtcaaattg agtcatcaag tctttaatat cgtttaaatt catacttatc
    33481 tattctccca acgtttgaaa gcaagaactg cattgtggcc tccaaaacca aaagtatttg
    33541 aaatagcgta tggaatttct ttctccaaac cttgtccata aacgacatta gcttcgatat
    33601 aatctgatac ttcacttgtc ccagctgtca ttggtacaaa gttatgacgc atagcttcga
    33661 tggtgacgat agcttctact gcacccgcag cccccagcaa atgtcctgta aaagacttgg
    33721 ttgatgatac aggtacttcc ttaccaagaa cagctacgat agcaccactt tctccttttt
    33781 cattggcagg agttgacgtt ccgtgagcat taacataggc tacttgctct ggagaaatct
    33841 cagcttcttc caaggctagt ttgatggcct tgatagctcc ctgaccttct ggatgtggag
    33901 aagtcatgtg gtaggcatca caagtatttc cgtaaccaac cacttcagcc aggatagtag
    33961 ctccacgttt ttcagcgtgt tcaagacttt ctagaaccaa catccctgaa ccttcaccca
    34021 taacaaaccc attgcgatcc ttatcaaatg ggatcgaagc acgagttgga tcctctgtag
    34081 tagagagagc tgttaaggct tggaaaccag cgatggcaaa aggtgtgata gaagcttctg
    34141 ttcctcccac caacatcaca tcttggaaac caaacttaat ggagcggaag gcatccccaa
    34201 tcgcatcatt tgatgaagag caggcagtat tgatagattt acaaacaccg tttgcaccaa
    34261 aacgcatggc tacattccca gaagccatat ttggtaaagc ttttggaaga gtcattggtt
    34321 tgacacgttt gggtcctttt tcatgaaggc gaagtacctg atcttcaatt tccttgattc
    34381 caccaatacc agatgcaacg ataacaccaa aacgatccct attaagagcc tctacatcaa
    34441 gattggcatg gtttacagcc tcttgggctg catacaaggc atataaagaa tagttatcaa
    34501 aacggttggt atcttttttt acaaagtatt tatcgaacgg aaaatcttgg atttctgccg
    34561 cattatgcac atcaaagtca ctatgatcaa attttgtaat gccaccaatg ccgattttcc
    34621 cagttgctaa actattccaa aattcttctg gtgtatttcc gattggagat gttactccat
    34681 aacctgttac cactactcga tttagtttca ttcttttcac ctctagcttt cgctacatac
    34741 ttaagccacc atcaatggca atcacttgac cagttagata atcttggcct gctaaaaata
    34801 ctgtcaaatc tgcaacctgc tctgcctgcc caaattcttt catcggaatc tgagctagtg
    34861 tagcttcctt aatcttatct gataagatag ctgtcatatc agactcaatc attcctggag
    34921 caatcacatt gactcgtata ttccgactag cgacctcgcg tgccacagac ttggtaaagc
    34981 caatcaagcc agccttagaa gcagcatagt tagcttgacc aatattcccc atcaaaccaa
    35041 caacactaga catattaatg atagcacctt ctctggcttt catcatcggt ttcaagactg
    35101 attgtgtcat attaaaggca ccagtcagat tgaccttgag cactttttca aaatctgctt
    35161 ctgtcatctt gagcataaga gtatcttggg taatccctgc attgttgacc aaaacatcta
    35221 ctgaacccag ttctgcaata gcttgatcaa tcatacgctt agcgtctgca aaatctgata
    35281 catctcctga aatgggaacc accttgatac catagtttga aaactcagcg agcaattctt
    35341 ctgagattgc cccacgactg tttaagacaa tgttggctcc tgcttgagca aacttgtggg
    35401 cgatggcaag accaattcca cgactcgaac ctgtaataaa gatattttta tgttctagtt
    35461 tcattttttt cctttcaaaa cttctactta ttttagtcta tttttctaaa agtgctacta
    35521 aactcgcttg atcttccaca tgagctaagt gagtagtttg atcaattttt ttaacaaaac
    35581 ctgacaagac tttccccggt ccaatctcga taaagttgct tatgcctgct tcttgcatga
    35641 ccccaatact ttcatagaaa cgaacgggtt ccttgacctg acgcgtcaag agctgagcaa
    35701 tgtcctcttt ttgcatcaca gcagcttctg tattgccgac taggggacaa gtaaaatctg
    35761 aaaaacttac ctgagccaga gtttcagcta gtttctggct agcaggttca aggagagagg
    35821 tgtgaaaggg acctgacacc ttaagaggaa tcaagcgttt ggcacctgct tcttgcaaaa
    35881 gttcaaccgc tcgatcaact gcaaccactt ctccagcaat gacgatttgt gcaggtgtgt
    35941 tatagttggc tggagtaacc actccaagtt cagaagcttt ttgacaggct tcttcaatga
    36001 cctctactgg cgtattgaga actgctacca tcttgccaga gtcagcagga gccgcttctt
    36061 ccatataggc tccacgctta gctaccaagg caaccgcatc ttcaaaatcc aaggcgccgc
    36121 ttgccaccaa ggcagagtat tctccaagag acaaaccagc aaccatatca ggctgatagc
    36181 ccttttcttg caataaacgg tagatagcaa ccgaagtcgc tagaatggct ggttgcgtat
    36241 agcgggtctg attgagtttg tcttcttccg tatcgatgag ataacgcaaa tcataaccta
    36301 gcacctgact cgctcgatca atcgtttctt taacaatcgg atactgatca tagaaatccc
    36361 gtcccatccc tagatactgg gcaccttgac cagcaaataa aaaggctgtt ttagtcattt
    36421 cttacaactc ctgtccagcg agaggcttct tcttgaattt tcttagcggc tccgtaatac
    36481 aaatctttta ggatttcttc agctgtttct tctttagaaa caagccctgc gatttgacct
    36541 gccatgacag agccaccctc cacatcaccg tgaacaactg ctttggctag ggcacctgct
    36601 cccatttgtt caaagatttc taaatcagga tcttcctgct taaaggcatc tttttcagcc
    36661 agttcaaaat ctctagtcaa ctgattttta atagcacgaa cagcatgacc aaagtgctga
    36721 gctgaaatcg tagtgtcaat atcccttgct tttaaaattt tctccttgta gtttggatgg
    36781 gcattcgact cttttgcaac tacaaaccgt gtccccacct gtacagcctc tgcacctagc
    36841 ataaagccag ccgcagcacc ttcaccatcc gcaattcctc ctgcagcaat aacaggaata
    36901 gatacagctg tggctacctg tcgcaccaag gtcatggttg ttaatttacc gatatgcccc
    36961 ccagcttcca ttccttctgc aataacagcg tctgcaccga ttttttccat gcgtttagct
    37021 aaagcgacac taggaacgac aggaataacg attatcccag cttcatggaa acgttccata
    37081 tacttgcttg gatttcctgc tcctgttgtg acaactttaa caccttcttc aataacgaga
    37141 tccacgatat cttccacaaa gggagataag agcatgatgt tgaccccaaa gggtttatca
    37201 gtcaatgatt tgattttatc aatattggcc ttgacaactt ctttcggggc atttccccca
    37261 ccgataattc ctaatcctcc agccttggaa acagcccctg ccaaatcacc atcagcaacc
    37321 caggccatcc ctccttggaa aataggatag tcaatcttca ataattctgt aatacgcgtt
    37381 ttcatagtgc ctccaacctt ccttgcttac gtaatagttc gatttcacca taatttgaca
    37441 gtcaaactat tacctaaaca agagggagtg ggtttctccc tactccttct actaatattc
    37501 tgcttatttt gcttgctctt caacgtaagc aaccaagtca ccaactgttt tcaagtcatt
    37561 ttctgcttcg atttggatat caaaagcatc ttcgatttct gagattactt ggaacaagtc
    37621 caatgaatct gcgtccaaat catcaaaagt tgattcaagt gttacttctg atgcgtcttt
    37681 tccaagttct tcaacgataa tttcttgtac tttttcaaat actgccatga taggactcct
    37741 ttaaaataaa tagttttttt ataacaatgt gttcaccaca tgattaccta aattgtaaga
    37801 atgagcgtgc cccaggtcaa acctccaccg aagcctgata gaagaacagt ctggctacca
    37861 tctaaaggga tgagaccttg ttctacacac tctgaaagta aaatcgggat actggctgca
    37921 ctggtattgc catattccat catattggct ggaagtttgg ctcggtcaac accaattttt
    37981 ctagccatct tatccaaaat acggtcattg gcttgatgaa gtagcagata atccaagtct
    38041 gtcacctcta taggagattc atcaatagtc tgcttgatag acttggctac atctcgaatg
    38101 gcaaaatcaa agactgtgcg tccatccatc ttcaaaaacg aatctgcact ttcttgatct
    38161 gaaaatggag aatgcaaacc tgaatgccca taagttaaac actcgctgcg acttccatcg
    38221 ctattgagac tctcagctaa gaaatgctct tgctcgctag cttctaacaa gacaccacca
    38281 gcaccatctc caaacaacac agctgttgat cgatccgacc aatcgactgc cttagagagg
    38341 gtttcactac caatcaccaa gcctttttga aagcgaccag aagcgataaa cttttcagca
    38401 gttgaaagag caaatacaaa tccactgcaa gccgcggtta agtcaaaagc aaaggcttta
    38461 ttagcaccaa tattagcttg aacacgagca gctgtagagg gcatcatcga atctggagta
    38521 atggtagcta ggatgataaa atccagttct tctcctgtta ttccagcttt tgccatcagt
    38581 ttcttagcaa cctctgtagc caaatcactg gtagattctg ttcttgaaat atgcctttgt
    38641 cgtattcccg ttcgacttga aatccactca tcattggtat ccataatctg agccaagtcg
    38701 tgatttgtaa ccacttgctc tggcacataa tgagcaacct gacttatttt tgcaaaagcc
    38761 attatttcaa atcctccaaa aattggtaaa gattagtcaa gcctttaccc atgacagcaa
    38821 tttcttcctc gctcatgcca tcaataattt tttctaccat ggccttgtgg aagcgtttat
    38881 gcagtctatg aatcaagcga cccttctttg tcaaatgcag atgcaccaca cgacgatcct
    38941 gttctgaccg aactcgctca atgtagccct tacgctctaa attgttcaaa cttgtcgtaa
    39001 cagttccaag agttaccatt aactcttttg acacttgact tggagtcaca tctggagcct
    39061 taccgatgac atcaatcgta tgcatttctt tgatggagat atccttaaaa cgactacctc
    39121 tcaagttcac ttcctcaatt acaaggacat tgttaaatat agatgttaaa tattcattga
    39181 ttcgttggta gtccattttt catatccctc cttcttcaaa aaacttttac aatcaaaaca
    39241 tttgacagaa agaattatat caaaattcaa agaatgatgc aagtattttt tattttcctg
    39301 taaatttagg tcttcttctc tccgaatgag ctcgcactcc ttctttgaaa tcctctgttt
    39361 gagctaagga tttctgtagg ttcagttcta aagtagcgta accctgccag tctttaaatt
    39421 ggctctccca aaccaacttc ttaatggcag cataggaatt acttgaagca cgtcttaatt
    39481 ttttaagaag ctgttctctc gtcttttcaa gtttttcagc ttcagaaacg cggtaaacca
    39541 acccccattc tagggctttt tctgccgtta aagcctctcc tgtcatagct aattgagcag
    39601 cacgcgtcac accgatactg cggctcaaga gatgaattcc ccctgcatct ggagccaaac
    39661 caacaccaac aaaggcttgg ataaacttag ccttatccgt cgccaaacag aaatctgccg
    39721 caacagccat attcgctgcg gcacctgcaa cagcaccgtc aacttccatt aaaacaggtt
    39781 tggctatttg cttgatttta taagaaatcg tattgaccaa ctctgcgatt tttgtcaatg
    39841 atggaatatc atcctcatcc actgcccgct tcatctctac caaatctccc ccaactgaga
    39901 agacctttcc attggcattg attaagataa aatgcacagc tggattttct tctgccaaag
    39961 tcagagcttc taaaatctcc tcacacatgg gaatatgaaa accatttgcg acctcaggac
    40021 ggttcaaggt aaggattgcc aagtcctctt caagctgata aataatgtgt tccatcaggg
    40081 ctccttttta ttttataagc agtttatact cttcgaaaat ctcttcaaac cgcgtcagct
    40141 tccatctgca acctcaaaac agtattttga gctgacttcg tcagtcttat ttacaacctc
    40201 aaagcagtgc tttgagcagt ctgcggctag cttcctagtt tgctctttga tttcattgag
    40261 tgttaaatta tttcactgtc aaagtatatc ttttttagga gcagaaagca agaaaaaatc
    40321 gactgaaagt gtctcagccg ataagaaagg ctcgctttag gctagaaagc atcttatttt
    40381 cttcattgaa aaaagccttt ctttctgcta taatcgtata aaatacttac tttaggagtt
    40441 cttatgaaag ttgttaaatt tggaggtagt tctcttgcct ctgctagtca attagaaaaa
    40501 gttttaaaca tcgtcaaaag cgattcagag cgtcgttttg tagtcgtttc tgcgcctggt
    40561 aaacgcaatg ctgaagatac taaggttacg gatgccctga ttaaatacta ccgcgactat
    40621 gttgcgggta acgatattag caagagccaa agctggatta tcgaccgcta tgctgctatg
    40681 gttagtgaat tgggactaaa accagctgtg ctagaaaaaa tttctaaaag cattcacgcc
    40741 ttggccactc ttcctattga agaaaatgaa tttctctacg atactttcct agcagccggt
    40801 gaaaataaca atgccaaatt gattgctgcc tactttaacc aaaatggtat cgatgcacgc
    40861 tatatgcacc ctagagaagc tgggattgtg gtcacaagtg aacctggtca cgctcgcatc
    40921 attccatcaa gttatgacaa gattgaagaa ttgacaaaca ccaatgaagt ccttgtcatt
    40981 cctggtttct ttggtgtcac taaggaaaat caaatctgta ctttctcacg tggaggttct
    41041 gatattacag gttctatcat tgctgctggt gtcaaagccg acctctatga aaactttacg
    41101 gacgttgatg gtatctttgc agcccaccct ggtattatcc accaaccaca ctcgattcct
    41161 gagttgacct accgtgaaat gcgcgagttg gcctatgcag gcttctcagt ccttcatgac
    41221 gaggctcttc ttcctgccta ccgtggaaaa attcctctgg ttatcaagaa taccaacaac
    41281 cctgaccatc caggtactcg tatcgttcta aaacacagta atgatgaatt tccagttgtg
    41341 ggaattgctg gtgactcagg ctttgtcagc attaacatgt cgaaatacct catgaaccgt
    41401 gaggttggat ttggccgcaa ggttctgcaa atcctggaag aacttaacat cggttgggaa
    41461 catatgccaa caggtatcga cgatctttct atcattctcc gttctcgcca actaactccc
    41521 atcaaggaag aagaaatcct gcgtcagttg gttcaaaagg ctaaagtaga tcatgcagaa
    41581 atcgaacacg acctttctat cattatgatt gttggtgaaa aaatgaagag ccacatcgga
    41641 gtgactgcta ctgcgacacg cgctctatct gaaaacaaaa tcaacatcca gatgatgtct
    41701 caaggttcta gtgaagtttc tattatgttt gttgtcaata aagaccaaga gaaagcagca
    41761 attaaagccc tctacaatgc cttttttgga gaaagtaagg aagactaagc atggcccaat
    41821 cacttaacaa aacagtactc ctcagtacga caggcacttc ctacctctct atcgctggga
    41881 aagttgggaa attccttgtc ggagatcagg ctttggaatt ttacccagat gtcaatgtcg
    41941 aacaatttat ccagattcct tggagccata tcaatcagat tggagccaat gtcactggac
    42001 gcaaaatcag ccgccacttc gaagtcttta cagacaaagg aaaattcctc tttgcttcaa
    42061 aagactcagg tgccattctc aaaattgcac gcgaaaaact aggcaatgac aaggtcgtca
    42121 aacttccgac cctgattcag acaattagcc aaaaatttaa aaatctattt gcaaaaaagt
    42181 agaaacttta gtataatcat agcaacggat aagtaggtta tcttcttctt tcagaaagtc
    42241 tgcgggtact gcgagcagat aggggggata ggtgaaattc taccgttagt aacaattaca
    42301 tacacaatca agtgcacacc tgtgaagttg gatggaaccg tggccctgcc actccaacgt
    42361 tttgtcaggc gtgctttttt cataaaggag ttcttatgtt agatatcaaa cgtattcgta
    42421 cagattttga agctgtcgca gaaaaattag ctacacgtgg tgtagaggct gctgtcttga
    42481 atgaaatgaa agaaatcgat gctaaacgtc gtaacatctt ggtcaaggtt gaaactctca
    42541 aagcagaacg taacacagtt tctgctgaga ttgcccaagc taagcgcaac aaggaaaata
    42601 cagatgacaa gattgctgcc atgcaaaatc tatctgctga ggttaaagcc ttggatgctg
    42661 aattggcaga aatcgatgct aaattgacag aatttacaac gactcttcca aatatcccag
    42721 ctgacagcgt tcctgttggg actgacgaag acgacaatgt ggaagttcgc cgttggggta
    42781 ctccacgcga gtttgacttc gaacctaaag ctcactggga tctcggtgaa gaccttggta
    42841 tccttgactg ggaacgcggt ggtaaggtaa caggcgctcg cttcctcttc tataaaggcc
    42901 tcggtgctcg tttggaacgt gctatctaca actttatgtt ggatgaacat ggaaaagaag
    42961 gctatactga agtcatcaca ccttacatag tcaaccatga ttctatgttt ggtactggtc
    43021 agtatccaaa atttaaggaa gatacttttg aactcagcga taccaacttt gtcttgattc
    43081 caactgctga agttcctctg acaaactact accgtgatga aatcttagac ggcaaagatc
    43141 ttccaatcta cttcactgcc atgagtccgt cattccgttc tgaggctggt tctgccggtc
    43201 gtgatacgcg tggcttgatc cgtttgcacc aattccacaa ggttgaaatg gtcaaatttg
    43261 ccaaaccaga agaatcttac gaagaattgg aaaaaatgac agccaacgct gaaaacattc
    43321 ttcaaaaact caaccttcca taccgtgtcg ttgctctctc tactggagat atgggcttct
    43381 cagctgcgaa gacttacgac ttggaagtgt ggattccagc acaaaacaat taccgtgaaa
    43441 tctcaagctg ttcaaacaca gaagatttcc aagcccgtcg tgcccaaatc cgttaccgtg
    43501 atgaagcaga tggcaaggtg aaactccttc ataccttgaa cggttctgga cttgcagttg
    43561 gacgtacagt ggctgcaatt cttgaaaatt accaaaatga agatggttct gtgaccatcc
    43621 cagaagcact tcgtccatac atgggtggag ctgaagtcat caaaccataa aaaataaggt
    43681 ttagctattt ctagctagac cttttttcgt aaccaaatca gataagcacc tagtacaaag
    43741 aataaaatag ttaggcatat aatggtttca gccaatacca ggtaatccag aaatggaagt
    43801 ttcaaaattc cctgagccat cttgagcgag gtcgctgtga taatggttgg gaaggtgagg
    43861 gctgagaagg ctggttgaaa accttgtttt aaaatgttgg gcagacgagt taaaacaaag
    43921 aaaaagaagg attgagaagc caaaatcatg acaatcaaga cccaagtcgg caggctggtt
    43981 cctcctactc gaactagaga agccaagagt agagagaaag gagcacagta gattccttct
    44041 tgtccaagca aggctagtgg gagtggatgt ttctttaaat cgctataaat aaggggatag
    44101 agatagaagg tcaagagaaa accaaaactc aaggtcgcat aggcaatttc gataatacct
    44161 accagaggat aggtcaaggc agccactgct atccccacat agagaaccgt ccaacttgga
    44221 gtggcatgaa ccctccgccc tgaacaagca aacttgatgg taaaaccagc aatcaaggtc
    44281 aaatccaaga gaaatgaaaa ccaccaaatc ccttgtgcta ccaaaggaag ataagagaat
    44341 acgcgaaaga cataggtcga taaaatcatc ccagccatag gaaaggttgc cattcctgac
    44401 aaaagagggg gcttggtcaa ttcttgcttg gtttctttcc aattaaagag atgcagaatt
    44461 agaaagtaaa tccataaaac caaaccagtc agactaaaaa gatgggatag aaccggcaac
    44521 gtatctaaaa taagatttcc agctcctgcc aaacctagca aacaacctga aaatactaag
    44581 gggagttttt tcatcctaac ctccaataat catgttagtt tcagtataac ataaaagcgc
    44641 ttaaatgagg atttaaaaaa acgaagtccg cttatttcag acttcatttt actcagatat
    44701 gaattaggca taaggttgca attctggatt aattggtgta ttagctaagt tgttggcata
    44761 gttacagagg attgctaggc tgacaccaaa aaccacatcc aaggcatttt gttgagtgta
    44821 gccagcttct aaaaactcag acaaggcttc atctcctaca cgacccttgg tattgataac
    44881 tgccaaggta aacttagcta gggtatccaa tttaggatct gtttcaattg gagtacgatt
    44941 gcgaagagct tgaatcaagt catcattcat ctggatttgt ttgatggaaa aggctgtgtg
    45001 acctgcgaca cagaaggcac aaccattggt cacggctgcc gtgatttgca ccacttcacg
    45061 ctcaacgggt gtcaggctgt tgcgacggtg gatagatgag acaatttggt aggcttctaa
    45121 aacagtcggg gcattggcca agagaccgat taggttggga atatagccat tgttgtcttt
    45181 ttctactgtt tcaagaattt ctttcacttc tgctggtgct gactctactg tatggatagt
    45241 aaatgttgtc ataagatacc tcttttctta ttattgacac taatattatt ggaaaatctt
    45301 ataaaatcct gattcctaag tttatctaag ataaagcttt attctctcat aagattttcg
    45361 ttgttatatt agtttatcac acttccaatc acttgcataa tatatattat atatcaggct
    45421 gataaaaatt atttataggc aaaaaaatca cacgagctgt gtgattccat tatttgtcaa
    45481 aatacttttt agtttcagca ataacgactg gcgacaagac caagagggca atcaagtttg
    45541 gcagagccat caaggcgtta acgatatctg cgataatcca gaccatatcc aactcgataa
    45601 atcctcctaa caagaccatg agcacaaaaa acacacggta gagccagata aagcgagccc
    45661 caaagaggaa ctcaaaacag cgttctccgt aatagttcca acctagaatc gttgtaaagg
    45721 taaaaagtac aaggaagatg gtcaagaggg caggcccaaa gtgtgaaaag actgttgaga
    45781 aagctgactg agtcaaggca accccattca agtcaccact ccaaactcca gttaccaaga
    45841 tggtcaaacc agttagagta caaatgatga gggtatcaat aaaggttcct gtcatggaaa
    45901 tcaaaccttg ctctactggt tcatttgtct tggcagctgc agctgcaata ggagcagaac
    45961 ccagaccaga ttcgtttgag aacacaccac gcgccacacc attttgaata gccatccgaa
    46021 cgctagcacc agcaaatcca cctaccgcag caaggggact aaaagctgag gtaaagacta
    46081 aagcgattgt gccagggatt tttccgatat taaagaaaat aactgtaaga gttcctaaga
    46141 tataaatgag ggccataaaa ggaacaacag tagttgaaac cttagaaata gacttgagtc
    46201 caccaaagac tgcaatcgct acaaagacag acaagacgag agctgtgatg gctggcgaaa
    46261 tcgtcgttgt attttggata gattctgtaa tcgagttgac ttgggtgaag gttccgattc
    46321 ccaagagagc aaccaatact cctgctactg caaacaaaac agcaagtggt cgccactttt
    46381 ctcccatccc tagaaggata tagtgcatgg gacctcccgc tactgcacca tggtcgtcct
    46441 tggtgcggta tttgatggcc aagagtcctt ccgcatactt ggtagccatt ccaaagaaag
    46501 ccgccatcca catccaaaat agagctcctg gtccaccaac cttgatagcc gtcgcaactc
    46561 ctatgatatt tcctgttcca acagttgatg ccaaggctgt acacagagct gcaaaactgg
    46621 atacatcacc atgtccctta tcctggataa aaataagctg aaaggccttg ggcagacgca
    46681 aaacctgcaa gagtcctagc cgcatggtta ggtaaatccc tgttccgacc aataaaatca
    46741 agaggggcgg tccccaagca aaagcatcga ttgatttaag caattctaac attttcttct
    46801 cctatcgttt caaccccaaa agaaagagca catgcaagat acatgtactc tggaatgctt
    46861 agataaatgc taaaaagcgg tctatcctag ctctgtcctt ttacctgaga gtttgagcag
    46921 ttgcctgcct tgccccttcg gtgcctttac ggtctctcca gagttccgtc catttacagt
    46981 catggaaaat caaacgattc cccacttcta ttaaacttca ttcggtgttg gtatttaatt
    47041 gattctaatt ttacaaaaaa tgttggcttt tgtcaatgtg tttattagta aaaattagtt
    47101 caacagtttt tactttataa agtccagaat actgctatcc tttaaaagtg acaatagtcg
    47161 caccactgcc tccagcattt tgtggggcat agccgaaact cttgacatgt ttgtttcttt
    47221 gcaagtattt ggtaactcct tcacggatga ctcctgttcc gataccatgg atgatatcaa
    47281 cttgagccat attgttaagc aaggcttggt cgatgaaggt atctagctca ttcatggctt
    47341 cttcatagcg cttgcctcga agatccagtc tagcttgagg tcctcgccca gaagttcgtt
    47401 tcacaacatt gacctgtttc ttcttgactg gtttttcttg ctgggcttga acaagatcaa
    47461 actctttctc ttccaaggtc atcttaatca agccaatttg ggcttcccag cggccgtcct
    47521 tgagttgact ggtcaaggta ccacgctgac cataactgag aaccacgata tcatctccca
    47581 cctttggagc tcgttttttc ttggcctttt gaaggacctt gtttttagac aagtccactt
    47641 tttcaggagc caattttttc aacttggcct tggcttcaat gatttcgtgg ggcttgagtt
    47701 gggatttact gtggagattt ttgagaatct ggtcactttc acttagggcc atatccacaa
    47761 tctcagcagc ctgttcacgc gccttgttaa gctcggtttc cttttcacga ttaagctcgt
    47821 tgtagagttt ttttagcgca cggttcatct tgagattttc ttgctccacc tcacggatat
    47881 tgtccaagcg tttgcggctt tccagcgtct gctcttctaa ttgctcaatg atacgattga
    47941 cgtcattgtc ctgatcgatc tgctgactgg catctcctac gataacttca gataggccta
    48001 gacgtttggc aatttcaaag gcattacttc ggccaggaac accctgcata aagcgatagg
    48061 tcgggcgaag agttgcagta tcaaactcca tactggcatt ttgcacaaag gctgtctcaa
    48121 taccgtaggc cttgagttct ggatagtggg tcgtcgccat ggtcttgatt tgacgcaggc
    48181 gaaggtcctc cagaatagcc atggcaaggg ctgctccctc ttggggatca gtaccagccc
    48241 ccaactcatc caaaagtaag agtgaatgtt ggttgacctt gccaagaata tccacgatat
    48301 tggtcatatg gctagagaag gtagacaagc tctgctcaat agactgctca tctccaatat
    48361 cagcaaagat ttcttcaaaa ataccaacac gacttccctt gtctgctaaa atcggcaatc
    48421 ctgactgggc catgacctgt gtcaagccca gagttttaag catgatggtc ttcccacctg
    48481 tattgggacc tgtaatgaca atagctgtta aatcttgacc aaaatagaca tcatttgcga
    48541 cggcattttt gaccaaagga tggcagacat ggagcagttg aatctcttga ttttctgaca
    48601 gctgaggcac gactgcttgt ctttcttgaa taaatcgaac cttggcacga atcaagtcca
    48661 gatgaccgat aatccaagcg tcattagcaa tctcagccgc atgagggcgg acacgctcag
    48721 aaatttcttg gagaatgcga agcatttcat agcgctcatc tgctcgcaga ctagcaattt
    48781 cttcgctcag tttgactacc tcacgtggtt cgatatagac ggtgtttcca ctagcagaaa
    48841 tatcatgaac gacacctgca atcttattgc ggtaggtgtt tttgactggt aaaacctgac
    48901 ggccatttct gctagcaaca attccttccg tcaacatctg ccctttttgc ttgagcaagt
    48961 cttgtaaaac atcgcgtacc tgactctcgc tatcatgtat ttttcgacgg attcgcgcca
    49021 attcttcact ggcaaaattt tcaatgaaac ccgcatcatt aaaggcctga agatttcctt
    49081 gtaattgcgg aaaatcatgt aatttctcaa accaaagggc taattcttcc aagctgacat
    49141 tttccagatt ggcgtaaaaa ctttgaagtt ctcggctggc aagaagcacg cgtttcaaga
    49201 gtaggaactc ctcgatattg agatccgctc ccatctccaa cctcttgcag actcctgcaa
    49261 tttccttagt tgagagaata gtaaaatgcg gttgctcgac gaaaagagcc tgcatttctt
    49321 tcatctcagc aaaagcctgt ttgattttat ctgctttggc agtcggagcc agctgtctca
    49381 attgctccaa gccctgctcg gtcaacaaat gaggctcaaa caaggccttg accttatcga
    49441 actctaatgt ttctaatatt ttcttattca tctttatttc cttgtctttg aatgtctagg
    49501 tgtggtagct ttttacattc tgatagattc gagtcaaatc tgtaaacaaa gggctaggaa
    49561 aactcctgcc ctttttatcc gattaaattt gtcacccaga tttgtttgag ccaactggtt
    49621 gttatcggta tgctctggat gatgtgtttt gcgacgatac tcttttcaag aggattttgt
    49681 ataactgcca tagggatggt cgccaagatt gtcaaggcca tttgcaagac aaataaggtc
    49741 accaacatgg acaagatacc tgctgaaact tggaacaact taccacccag ttttttgcta
    49801 ggaatcaagt gtaagagaag accaagcaaa cgaccaatgc tatagacaat cccaaataca
    49861 agcaagtagc cgatacctgc ataaaagacc ttatccagct gaaagagttg atccgatggg
    49921 aaaaagaaag tcccctgacc ttcctgcgaa tttgcataag ggagcaataa atggaattgc
    49981 tctccaagcc ccttataaaa ctggccagcc ataaaagccg atgccatggc tgaaatcagg
    50041 taataaacct gtaagagcag gcctctccga tagccgatat aaaatcccca aaccaagacc
    50101 aatagaagaa ggaatgaaat cataaggaat cctcaatctt gctctgttct tgcttacaag
    50161 tcacaagctt gtgacggagt tcttctagct cttgctcctt atcgtcaaat tcaatctcac
    50221 ggctgagctg agttgataaa cagttgactg ccaacaaaag agcgattgtt tcatcatctg
    50281 cgctaggcat ttgttcttta attgcttggt atttttctgt cgcaacctta gcgatttcct
    50341 ccataaaaag gttatcatgt tcgcttgtca aggttaacgt ttttttcccg aatgtaaatt
    50401 tgaatcgatt tagatttgcc ataaaattca cctcacgata ttataccaaa attcgctaat
    50461 tttgtcagtt tttacaaatt ttactgcttt tgtggtacaa tagaaactat ggcaagtatc
    50521 acactcacac caagcgaaaa ggatattcag gcttttcttg aacactatca aaccagtctg
    50581 gctcctagca agaatcccta tatccgctac tttttgaaac tacctcaagc aacggtttct
    50641 atctatactt ctggaaaaat cttgcttcag ggtgaagggg ctgaaaaata cgccagtttc
    50701 tttggctatc aagctgtaga gcaaaccagc ggacaaaatc ttcctttaat tgggacagat
    50761 gaggtgggaa atggttccta ctttggtggg cttgcagttg tggctgcctt tgtcacacct
    50821 gaccagcacg actttttacg aaaactcggt gtgggggatt ctaagactct gaccgaccaa
    50881 aagatccgtc agattgctcc tattctcaag gaaaaaattc agcaccaggc actccttctc
    50941 tcacccagca agtacaacga ggtcatcgga gaccgctaca atgctgtttc ggttaaggtt
    51001 gccctccata atcaggctat ctatctcctc cttcaaaaag gtgttcagcc tgagaaaatt
    51061 gtgattgatg cctttaccag tgctaaaaat tatgacaagt acttggcaca agaggccaat
    51121 cgtttcagca atcctatcag cttagaagaa aaggctgagg gcaaatactt ggctgtcgca
    51181 gtttcttctg tcattgcgcg tgatctcttt ctggaaaatc ttgaaaatct gggacgagaa
    51241 ctgggttatc agctcccaag tggagctgga acagcttctg acaaggtggc tagccagatt
    51301 ttgcaagcct atggtatgca gggactcagc ttctgcgcca aattgcactt taaaaacact
    51361 gaaaaagcga aaaaacgctt agaaaggtaa gttatgaatt catttaaaaa tttcttaaaa
    51421 gagtggggat tgttcctcct aattctgtca ttactagctt taagtcgtat ctttttttgg
    51481 agcaatgttc gcgtagaagg acattccatg gatccgaccc tagcggatgg cgaaattctc
    51541 ttcgttgtaa aacaccttcc tattgaccgt tttgatatcg tggtggccca tgaggaagat
    51601 ggcaataagg acatcgtcaa gcgcgtgatt ggaatgcctg gcgacaccat tcgttacgaa
    51661 aatgataaac tctacatcaa tgacaaagaa acggacgagc cttatctagc agactatatc
    51721 aaacgcttca aggatgacaa actccaaagc acttactcag gcaagggctt tgaaggaaat
    51781 aaaggaactt tctttagaag tatcgctcaa aaagcccaag ccttcacagt tgatgtcaac
    51841 tacaacacca actttagctt tactgttcca gaaggagaat accttctcct cggagatgac
    51901 cgcttggttt cgagcgacag ccgccacgta ggtaccttca aagcaaaaga tatcacaggg
    51961 gaagctaaat tccgcttctg gccaatcacc cgtatcggaa cattttaaga aacctaagag
    52021 gccgagaatc accaatctca gcctcttctt ctatcgtgag aagtgattgt ttattgacaa
    52081 atactcaatg aaaatcaaag aacaaactag gaagctagcc gtaggctgct taaaacagtg
    52141 ttttgaggtt gcagatggaa gctgacgtgg tttgaagata ttttcgaaga gtataaaata
    52201 aaaacaatcc caactctcac ctattcatgc aaaggaattt tatggaagtt tatttttcag
    52261 gaaccattga acggattatt tttgaaaatc ccagcaattt ttatcgcatc ctcctcctag
    52321 aaatcgacga tacggacgca gaggattttg atgactttga aatcattgtc acaggaacca
    52381 tggctgatgt aattgagggc gaagactata ctttttgggg gcaaattgtc cagcactcca
    52441 agtatggaga acaactgcaa atcagtcgtt atgatcgcgc aaaaccaact agtaagggct
    52501 tggtcaagta cttttcaagt agccatttca aggggattgg tctcaagaca gctcagaaaa
    52561 tcgtggatac ctatggcgaa aataccattg acgaaatttt gcaacaccca gaaaagttag
    52621 aaggcatcgc aggactctct gccaaaaatc gcgaggcttt cgtctccact ctccgtctca
    52681 actacggtac ggagatggtt ttggccaaac tagccaacta cggcattccc aacaaactag
    52741 cctttcagat tcaagacttt tacaaggaag aaacccttga tgtggttgaa aattatccct
    52801 accaactggt tgaggatatc aagggtttgg gctttaccat tgctgaccaa ctagctgagg
    52861 aactaggcat cgaaagtcag gctcctgaac gcttccgcgc cggtctagtt cacagtcttt
    52921 ttcaggcctg tatggaaaca ggagacacct atgttgaagc acgggatttg ctggaacaaa
    52981 cccttactct ccttgagtct tcccgtcccg tggaactaga ccccagccaa gttgcccaag
    53041 agctctccta cctgatcgaa gaagacaagg ttcagcagat tgataccaag atctttgaca
    53101 acagcctctt tttcgctgag gaaggcatcc gcagtcactt ggttcgtatc cttgaaaaag
    53161 gaaaacagaa gagtcatgat ttagaaacca ttcaaaaaca tatcactact atcgaggaag
    53221 agctgggaat tgagtatgat aacattcaaa aacaggctat ctgtgacgct atccagaaca
    53281 aggtctttat cctgacaggt gggcctggta ctggtaagac aactgttatc aatggaatca
    53341 tcgctgttta tgccctttta gaaggacttg acttcaggaa gaaaaacaat ctgcccattc
    53401 ttcttgctgc tccaactgga cgagccgctc gccgcatgaa tgaattgaca ggtttgccta
    53461 gcgcgaccat acaccgccac ttgggaatga caggtgacga tgataccagt catctggaag
    53521 attacctaga tgctgacttt atcatcgtgg atgaattctc tatggtggat acttggctgg
    53581 ccaatcaact cttctccaat atctcttcta acagtaagat cctcatcgtg ggtgacagtg
    53641 atcagctacc ttctgtcagt cctggacagg ttctagcgga tctgcttcat attcctttga
    53701 ttcctcagac tcgcttggaa aaaatttatc gacaaagcga agaatcaacc atcgtcaccc
    53761 tagctagtca gattcgacag ggcatcttgc cagctgattt cacccaaaaa aaagctgacc
    53821 gttcctactt tgaaattgct agtggccata ttcctgccac tattgaaaaa atcttaggtg
    53881 ccgccctcag aaatagtatt cctgcccgtg atatccaagt tctggctcct atgtaccgag
    53941 ggacggcagg gattgatgct atcaatcagc tcatgcaaga cctgctcaat cccccacaaa
    54001 aagatcaact cagttttgaa gctcctcagt gccactatcg taagggagac aaggtcattc
    54061 atttggttaa cgatgctgaa atcaatgtct ttaatgggga tttaggagct atcacagacc
    54121 tgattcctgg taaatacacc gaatcgaaac aagacgagat tgtcattgat tttgatggta
    54181 atgaagtctc ttacccccgt aacgaatggt acaagattcg cttggcctat gccatgagta
    54241 ttcataagtc tcagggaagt gagttcccag ttgtcatcct accgattact agtgctagcc
    54301 gacgtatgct ggagcgaaat ctcatctaca cagccattac acgtgccaaa agcaaactca
    54361 tcttactagg cgaattacaa gccttcgact atgctaccca acacatcgga actgcccgaa
    54421 aaacctatct gattgaacgc ttcagtgatc tactggagaa tgttgaagaa aagcaacaag
    54481 ctgtctctga aacagtcaca tcaagtgcct ctgaacaatc ctacatccta accgaagaaa
    54541 actgggacag cattccagcc atgattggga ttacagacac agacctcaaa gagatttttg
    54601 gaaaatagtg catcagaaaa accaccaatt caggtgggtt ttctgtttat taagattatt
    54661 ttactgttgc tgtgcttgtg atcaattcaa cagctttttt gatagtgata tcatgtttca
    54721 acatgtcagc tgaaagcaag ttttgaactt gtgcaacttc catgttgtag tctgctgcca
    54781 attgctcaac ttctttttgg atttcttctt ctgaagcatc aaatccttca gctttggcaa
    54841 ctgcttcgat aacaaggtta gtcttagtac gtgactcagc ttctgcttgg tattggttgt
    54901 gaaggtcttc ttgagtagtt ccagtgattt ggaagtacat gtcagggttg atcccttgac
    54961 gttgcaaatt cccaaggaat tcatttactg aacggtgaac ttcttcatgg atcatttctt
    55021 ctggaagttc tacgatttca gcattttcta cagctgtatc aattgctgca ccttcaactg
    55081 catctttgta agcttcttct ttagcagcag ccaattcttt gcggtatttt tctttcaagt
    55141 cagcaagtgt ttcaacttct tcatcaatgt cttttgcaag ttcatcgtca agagctggaa
    55201 cttctttagc ttttacttcg tggatagttg tcacgaattt agcttcttta cctgcaaggt
    55261 cttctgcttg gtagtcttct gggaatgtta cgataacatc aacggtttcg ccagctgagt
    55321 gacctaccaa ttggtcttcg aaaccaggga tgaattgacc tgaaccaagt ccaagtgaga
    55381 agttttcacc ttttccaccg tcaaattcaa caccgtcgat agaaccaacg aagtcgatca
    55441 caacagtgtc gccgttttca gcagcagctt ccttgataac caattcagcc aggttgttgc
    55501 gttcgcgttc gatacgctct tcgacatcag cgtcagttac ttctttttct acatcaactg
    55561 atacttcaag gtttttgtag tcacccaatt ttacttcagg ttttgtaacg acttcagcag
    55621 tgataaccca gtcttgacct ttttccattg aagttacgtc aatttttggt tgggcaacca
    55681 cttcaagacc agcttctttt acagctgctt cataagcgtt tggcaaaaga gcgttcataa
    55741 cgtcttggta aagtgattct tcaccaaatt tttggtcgaa gataggacgt ggaaggtgac
    55801 ctttacggaa acctggaaca ttaagagatt tcttcactga cttgaagaca cggtccaatt
    55861 ctggtttgat ttggtcttga gagatagtga aagtcaagac accacggttt gtttctttgt
    55921 tttcaaatga tacagacatt ctgtcatttc tccttaaaat tttttaaata cagtctatta
    55981 taacattttc tataaataaa atctagacta atgcagccaa ttatagacaa caagcctttt
    56041 tcctaactaa aacactcata aagtatagac aattttagac tactttggat atcttttggt
    56101 tagtcatttt ccaaaactaa tttatctaat ttttcagtta tatagta
//
LOCUS       DAVLBE010000009        51545 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.009, whole genome shotgun sequence.
ACCESSION   DAVLBE010000009 DAVLBE010000000
VERSION     DAVLBE010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 51545)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51545)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51545
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.009"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            226..6660
                     /locus_tag="VXB91_000560"
     CDS             226..6660
                     /locus_tag="VXB91_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEV0470063.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPNEVVLADTSSSEDALNISDKEKV
                     VLDKETENKEKHEDIHNAIETSKDTEEKKTTVIEEKEVVSKNPVIDTKTSNEEARIKE
                     DSNQSQGDNAHSSANKGTENPKKEDRLVYIAEFKDKESGEKAIKQLSNLKNTKVLYTY
                     DRIFNGSAIETTPDNLDKIKQIEGITSVERAQKVQPMMNHARKEIGVEEAIDYLKSIN
                     APFGKNFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKI
                     PHAFNYYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQ
                     IFSYKMYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRAL
                     RKAGIPMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQT
                     VEFDKVNIGGESFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDL
                     RGKIAVMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGT
                     KSQVFSISGDDGVKLWNMINPNKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVG
                     DEKEIDFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVIN
                     GKSTYGYMSGTSMATPIVAASTVLIRPKLKEMLERPVLKNLKGDDKIDLTSLTKIALQ
                     NTARPMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYGS
                     ISLKEIKGDKKYFTIKLHNTSNRPLTFKVSASAITTDSLTDRLKLDETYKDEKSPDGK
                     QIVPEIHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFESV
                     EEMEALNSNGKKINFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSRSKTLGGYDDDGK
                     PKIPGTLNKGIGGEHGIDKFNPAGVIQNRKDKNTTSLDQNPELFAFNNQGINAPSSSG
                     SKIANIYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQRDLKVIS
                     REHFIRGILNSKSNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPATK
                     IRGQFEPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLIT
                     KDTYHKVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTYA
                     GEGQGRNRKLDKDGNTIYEIKGAGDLRGKIIEVIALDGSSNFTKIHRIKFANQADEKG
                     MISYYLVDPDQDSSKYQKLGEIAESKFKNLGNGKEGSLKKDTTGVEHHHQENEESIKE
                     KSSFTIDRNISTIRDFENKDLKKLIKKKFREVDDFTSETGKRIEEYDYKYDDKGNIIA
                     YDDGSALQYETEKLDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNSYKSIE
                     IKATKYDSHSKTMTFDLYANINDIVDGLAFAGDMRFFVKDDNRIKAETKIRMPEKNKE
                     TKAEYPYVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKG
                     YALKVTTYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRVLSETTIYADSRNVEDGRST
                     QAVLMSALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDK
                     SNVEAIKEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNW
                     ELRVNESVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMD
                     GNVYLQTGYSDLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKR
                     NNGFDGEIQEQHIYVNGKEYTSFDDIKQITDKTLNIKIVVKDFARNTTVKEFILNKDT
                     GEVSELKPHRVTVTIQNGKEMSSTIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKK
                     DAGYVINLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDL
                     QREDHSQKSDSTKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIV
                     GIFLGLKKKNQD"
     gene            7292..7768
                     /locus_tag="VXB91_000561"
     CDS             7292..7768
                     /locus_tag="VXB91_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0470064.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEHLFDQVATLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKDLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPDK
                     EVEVSLLFFIINNSSSSQTNILAQLMDFFTGNGHLEDLSKISEPEKLYAYIAEATA"
     gene            7806..8111
                     /locus_tag="VXB91_000562"
     CDS             7806..8111
                     /locus_tag="VXB91_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0470065.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRIPAMSAPVFDNIEAAIKEHGLS"
     gene            8159..9634
                     /locus_tag="VXB91_000563"
     CDS             8159..9634
                     /locus_tag="VXB91_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HEV0470066.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNGAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNVVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQEVSLFIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLRGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVVFLVFYIGIFAWYRKQMIKRNEEYAAKAK"
     gene            9984..16685
                     /locus_tag="VXB91_000564"
     CDS             9984..16685
                     /locus_tag="VXB91_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HEV0470067.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTAEKPKEEKMIVEEKADKALETKNVVERTEQSEPSSTEAIASEKKEDEAV
                     TPKEEKVSAKPEEKAPRIESQASSQEKPLKEDAKAVTNEEMNQMIEDRKVDFNQNWHF
                     KLNANSKEAIKPDADVSTWKKLDLPYDWSIFNNFDHESPAQNEGGQLNGGEAWYRKTF
                     KLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLHKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIVNTDDKDHELVAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLATVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKALRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGLKTFNKKQTSDGRTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SSQVTVFTGKKEGQEKTVLGTEVPKVQTIIGEAPEMPTTVPFLYSDGSRAERPVTWSS
                     VDVSKPGIVTVKGMADGREVEARVEVIALKSELPVVKRIAPNTDLNSVDKSVSYVLTD
                     GSVQEYEVDSWEITEVDKAKLSVAGSRIQMTGQLAGETIHATLVVEEGNAAAPVVPTV
                     TVGGEAVTGLTSRQPMQYRTLSYGAQLPEVTASAENADVTVLQASAANGMRASIFVQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKPGAVTLKAEYEGAKGQVELTIQANTEKKIAQSIRP
                     VNVVTDLHQKPTLPTTVTVEYDKGFPKAHKVTWQAIPKEKLDSYQTFEVLGKVEGIDL
                     EARAKVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVAWDAIRPEQYA
                     KEGVFTVNGRLEGTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRTNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     APKSYVIEYYVGKTVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKAPAQLKAGEMNHF
                     SFDKVETYAVRIRMVRADNKLGTSITEVQIFAKQVAAAKQGQTRIQVDGKDLANFNPD
                     LTDYYLESVDGKVTAVTASVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKNLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDGYETKNLTVEWEEVPAEN
                     LIKAGQFTVRGHVLGSDLVAEVTVRVTDKLGEALSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDHSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVAQAKLHFFA
                     DSGTDAPTKLVLERYVGPEFEVPTYYSNYQAYDADHPFNNPENWEAVPYRADKDIAAG
                     DEINVTFKAVKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGEDSLPVLVRLVSESGKQVKEYR
                     IQLTKEKPVSEKTVAAVQEDLPKLEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKTGK
                     ERIFTAINPDGSKEEKLREVVEAPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSE
                     ASQTNKAQLPNTGSAASQAAVAAGLALLGLSAGLVVTKGKKED"
     gene            complement(16933..17789)
                     /locus_tag="VXB91_000565"
                     /pseudo
     CDS             complement(16933..17789)
                     /locus_tag="VXB91_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270419.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(18000..18359)
                     /locus_tag="VXB91_000566"
     CDS             complement(18000..18359)
                     /locus_tag="VXB91_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HEV0470068.1"
                     /translation="MGMILMKLASILLLILTLVVCIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLALSFLAIILVFFFLLKKRSFYYPKFIKFFWRTGFL
                     LTLIMYIEMIVELFLMK"
     gene            18451..19407
                     /locus_tag="VXB91_000567"
                     /pseudo
     CDS             18451..19407
                     /locus_tag="VXB91_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002881980.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein.; internal stop;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
     gene            19391..19948
                     /locus_tag="VXB91_000568"
     CDS             19391..19948
                     /locus_tag="VXB91_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV0470069.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLAKQVY
                     AFDIQKQALEKTQERLHQAGLTNAQLILQGHETLDQFVTKAKAGIFNLGYLPSADKSV
                     ITRPQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            19941..20195
                     /locus_tag="VXB91_000569"
     CDS             19941..20195
                     /locus_tag="VXB91_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0470070.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTYHERAVGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            20207..22261
                     /locus_tag="VXB91_000570"
     CDS             20207..22261
                     /locus_tag="VXB91_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HEV0470071.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYY
                     AYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLVLPHLSDEEEESKDYLMHIAILNEVTLELEKELEDTRNKLSLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKDKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETAIISSGAFVERVINRVKPNNID
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            22440..23300
                     /locus_tag="VXB91_000571"
     CDS             22440..23300
                     /locus_tag="VXB91_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HEV0470072.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLCFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSMNFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQLLFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNISNRKISYTLPGSAFV
                     LLVILGLLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLRDPVFKKD"
     gene            23511..24221
                     /gene="ccdA2"
                     /locus_tag="VXB91_000572"
     CDS             23511..24221
                     /gene="ccdA2"
                     /locus_tag="VXB91_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEV0470073.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGLLVLFGNASILSQLFE"
     gene            24241..24807
                     /locus_tag="VXB91_000573"
     CDS             24241..24807
                     /locus_tag="VXB91_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HEV0470074.1"
                     /translation="MKKWQTCVLGAGSLLCLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            24818..25930
                     /gene="msrB"
                     /locus_tag="VXB91_000574"
     CDS             24818..25930
                     /gene="msrB"
                     /locus_tag="VXB91_000574"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEV0470075.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKAVKKTEISEDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
     gene            26288..27025
                     /locus_tag="VXB91_000575"
     CDS             26288..27025
                     /locus_tag="VXB91_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0470076.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFNYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
     gene            27022..28713
                     /locus_tag="VXB91_000576"
     CDS             27022..28713
                     /locus_tag="VXB91_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV0470077.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSTGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIDTGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VAFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYHMKIDSRPQKGTKVEIYINRIETS"
     gene            28829..29392
                     /locus_tag="VXB91_000577"
     CDS             28829..29392
                     /locus_tag="VXB91_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HEV0470078.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGALFVLGLSSSEVLGGHIG
                     KESSQEIGELIVETILDILGSRGIHLAVQGCEHVNRALVVERQVAEQFGLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALASRPKLIGGARAHYPQDAIRKT"
     gene            29414..35083
                     /locus_tag="VXB91_000578"
     CDS             29414..35083
                     /locus_tag="VXB91_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FIVAR domain-containing protein"
                     /protein_id="HEV0470079.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEII
                     SQEAKDLIQTGKPDRNEVVYGLVYQKDQLPQTGTEASVLTAFGYLSGDILKTLGLDTV
                     LEETSAKPGEVTVVEVETPQSTTNQEQARTENQVVETEEALKEEAPKTEESPKEEPKS
                     EIKPTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKPEEKVAVKPESQPSDKPTEEPKV
                     EQVGEPVEPSEDEQAPTAPVEPEKQPEAPEEEKAVEETPKPEDKIKGIGTKEPVDKSE
                     LNNQIDKASSVSPTDYSTASYNDLGPVLETAKGVYASEPVKQPEVNSETNKLKTAIDA
                     LNVDKTELNNTIADAKTKVKEHYSDRSWQNLQTGVTEAEKVAANTDAKQSEVNSETAS
                     LKTAISRLNTDKVELENQLKIAQGKTETDFSMESWTVLSTAKNKAQEVKDNGTATQEQ
                     INEAEKSLKTALADLSVDKTALGSAIDTATKKNKENYTNQTWAELETALTAAKSVNTN
                     ESKQSDVNEAAEKLTATMEKLVELSEKPRLTLSIEKRDIDRKATVTYTLENPANTQIK
                     SITATLKKGEEVVKDFVLTEENLKTNHLTALFEKLDYYKEYTLSTDMVYNRGNDDETE
                     SISEELIQLNLKKLELKDIQTVSLMKFENGQESQVTHLSDKPTDLSKLYLKVTSSTSK
                     DAVLAVSSIEEEIIENKKIFKIHADTPELVVRKKDGSLSKGFDYYMERVIPHDGDIYY
                     DFKDLISAMTSNPTGTFILGRDISSRNVKPDGNGKSYIKGEFKGKLLGTNDNVRHSIF
                     DLEYPLFDTIKSGVVKDIDFKHVNMVFPDSNQGDNVATIARVIKDKTKIENVNVEGYL
                     EGRDHVAGLVNNLEGNSEIENVSFTGKIKSKGGNSITAGIAGRNILSRVKRAYVNADI
                     EVHRSSNSSMLVAVNGINADASGGWGTWGRLTESVAKGTLETKQGGQAGGASSTVWPY
                     GAIDNVVSYAKVTKGKELFGSDGDLNYDWFMKKISNIFGVQGISSGDSGSDSKFTRIS
                     EEEANQKVASYNITAPNLMSDSSLLVDRLNESWKNTDQFESIQDYQAQNQLIYQNLTK
                     FTPYYNKEFIVHEGNALTPEQEILKTKKIKSIVGLKGTEFVVDGSDIDTIMLHFEDGS
                     QKRYKVTSTGKFSITNLPEYQVEDLNVVYTSEHIVHPLDSSLINNLVEELKKVELYTE
                     STYQVLGIDKDNANKLNRTKRLFLDESLDAVKTQLPTFVKTMFENEWLHINGESSGAV
                     AALRQKIMDNKTAILLALTYINRYYDVKFSDYNIKKLMLFKPTFHGEKIDLLDRLIRL
                     GSSGENRLKGSENAETFKQLFASETKQKDLVTYLDYNRSLLTNYQTTGEWFKETTKDY
                     IQFEERPSLVEEIKDAKYRVYDNLTAPYYQGYILPLLTLKNTHLAILSNYSTMTFVSR
                     EKRPNWKNEDFDKWVKYVATAHRNHVDTWYKILPDNIKGKMVKENVTAVWEGLSIPGS
                     EWVDQNAVDRKGRDYAPAREFFNLVGGPMGGWYAYHGYGAHAGGRNRVNYEVFDVLSE
                     YGISVFTHELTHVNDTWIYLGGYGRRENMGPEAYAQGLFQSPVPGQPGWGALGLNMAF
                     ERKNDGDLIYNASPTQFENRKELDSYMKNYNDTLMMVDYLEGDAVISKGKEAITKWFK
                     KVEPKVVSQTAQYDTVRQLTAEEKEKLSVSSVDDLVDQGLMSDRAVGNNTYNPADFET
                     SYIAIDYMTGIYGGGKNSVGSPGALMFKHNTFRMWGYYGFEEGVLGYASNKFKQASRD
                     EGHAGLSDNFIISKISKGEFLTMEAFKKGYFKKVVEELKTKGIRPVTINQKTYSTFEE
                     LQEGFKQAVERDLKKNQLDERETRNFKFQVFRQLLQQTDSFKTSIFR"
     gene            35144..36865
                     /gene="pabB"
                     /locus_tag="VXB91_000579"
     CDS             35144..36865
                     /gene="pabB"
                     /locus_tag="VXB91_000579"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000554849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HEV0470080.1"
                     /translation="MHRKTVIDFRTLGERYTFTQPIKELKTRNVEEVADLLAQVESYQ
                     EQGYYVVGYVSYEAAPAFEEKLAVHKDPLLGEYLLYFTVHDSVETSPIPLTYEDIDLP
                     SNWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLNANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     EIFHSLFPCGSITGAPKIATMEIIKDLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGKISQKQLMFEE
                     QHLERLRKASRYFAYPFDPEILRQKIEAECQTCDANQDYRLRISLSKSGEIEFSRQIL
                     TPLSPSFCQAKLCLQEANLNQSFTYFKTTYRPHLSIEEQEKIYHNGKGELLETSIGNL
                     VLKIDGKLYTPPIRLGILPGIYHQYLLETGQVEEKVLTLADFAQAEAIYGCNAVRGLY
                     ELQVIGL"
     gene            36985..38511
                     /locus_tag="VXB91_000580"
     CDS             36985..38511
                     /locus_tag="VXB91_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV0470081.1"
                     /translation="MKSKIVLGASLAIATLSLVSLVEIEGLSPFLIENVSANTHSANK
                     VINHKVSIYLENADEGKGLTVNFSTDSVSPNLFDEFEKKSGITITTMLVNAKTGEVVE
                     KRLTPSVFLRSNDLTSGTISSFIFSEYPDGEYKYVVSKGDFIDPKTQFKHQYRGESPV
                     FRIRNRKYVELGTTDKKLDERRDNSVYKDGVVEHKVNLSLTSYQGGNGVTAIFSTDSV
                     NSNLLNSFGEKAKKVLIRSKLINVKTGEVIDETFSPKVSLTSKILKSGSTAVFYFIDL
                     TDGEYKYVAYESQQYTDPQTTLTHQYRGESPIFSIKDGKFSGLVSASKPDENPKPTPK
                     PDEKPKPSAPQQEKTKPTVQSGWVGSSYYQNGKKVTSKWIFDKKYNSYFYLDASGNYV
                     QNAWVGNYYLKSGGYMAKSEWIYDKNYGSYYYLTSEGSYARNTWSGNYYLKSNGKMAK
                     SEWVYDSNYKSYYYLTSEGSYARNTWVGNYYLKSNGKMAVNERTPDGYRVDGSGKWVK
                     "
     gene            38598..39517
                     /locus_tag="VXB91_000581"
                     /pseudo
     CDS             38598..39517
                     /locus_tag="VXB91_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811638.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
     gene            39652..40611
                     /locus_tag="VXB91_000582"
     CDS             39652..40611
                     /locus_tag="VXB91_000582"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HEV0470082.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDRDKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPISCTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENSFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            40708..41547
                     /locus_tag="VXB91_000583"
     CDS             40708..41547
                     /locus_tag="VXB91_000583"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HEV0470083.1"
                     /translation="MTKADTIFKENIECILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPITTLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRVDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(41595..41765)
                     /locus_tag="VXB91_000584"
     CDS             complement(41595..41765)
                     /locus_tag="VXB91_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001051775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HEV0470084.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            41886..42770
                     /gene="miaA"
                     /locus_tag="VXB91_000585"
     CDS             41886..42770
                     /gene="miaA"
                     /locus_tag="VXB91_000585"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HEV0470085.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKRFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVPHHLIDVREITESYSAFDFVSEAKMTIEDIQSRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHLVEQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQEILYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTFEEARESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            42763..44001
                     /gene="hflX"
                     /locus_tag="VXB91_000586"
     CDS             42763..44001
                     /gene="hflX"
                     /locus_tag="VXB91_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HEV0470086.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     SYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDG
                     EVITGYISEKNKWRLEEFYD"
     gene            43994..44617
                     /locus_tag="VXB91_000587"
     CDS             43994..44617
                     /locus_tag="VXB91_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HEV0470087.1"
                     /translation="MTDIKTLALKYGGYTSLDKVYLDQLLAGKTDQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKPFIRLNLSGKSFGFCY
                     ESDGLGRIFFENEEKISDDLLFEIAQIFPHQLVFEESGKIYMKPVEDEEVISLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            44632..45561
                     /locus_tag="VXB91_000588"
     CDS             44632..45561
                     /locus_tag="VXB91_000588"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HEV0470088.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTIRPRKVSKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAEKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTGASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            45582..46337
                     /locus_tag="VXB91_000589"
     CDS             45582..46337
                     /locus_tag="VXB91_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEV0470089.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEPDAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(46391..47299)
                     /locus_tag="VXB91_000590"
     CDS             complement(46391..47299)
                     /locus_tag="VXB91_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEV0470090.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLAHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            47363..47632
                     /locus_tag="VXB91_000591"
     CDS             47363..47632
                     /locus_tag="VXB91_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HEV0470091.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            47632..48012
                     /locus_tag="VXB91_000592"
     CDS             47632..48012
                     /locus_tag="VXB91_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV0470092.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNEEFEALIRTGQ
                     LIDLRDPAEFHRKHILGARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            48101..48328
                     /locus_tag="VXB91_000593"
                     /pseudo
     CDS             48101..48328
                     /locus_tag="VXB91_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660075.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(48368..49093)
                     /locus_tag="VXB91_000594"
     CDS             complement(48368..49093)
                     /locus_tag="VXB91_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase"
                     /protein_id="HEV0470093.1"
                     /translation="MRLDNLLAQEKISRKAMKQALLRGKILVDGCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVEVNGLLTPDHIQAFQKGIVFLDGTVC
                     KPAKLEILSASPSISQASITISEGKFHQIKKMFLSVGVKVTILKRIQFGDFTLNPDLA
                     ESNYRPLNQKELQIIKNYLEMSR"
     gene            49255..51096
                     /gene="typA"
                     /locus_tag="VXB91_000595"
     CDS             49255..51096
                     /gene="typA"
                     /locus_tag="VXB91_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HEV0470094.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            51116..51370
                     /locus_tag="VXB91_000596"
     CDS             51116..51370
                     /locus_tag="VXB91_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HEV0470095.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLLLAYFSVRDITLMPVKKSKRR"
BASE COUNT        16550 a         9076 c        11158 g        14761 t
ORIGIN      
        1 taatcttatt ttttaacgtg tgctaaaaaa taaattaatg catgttaatt tttcttgaat
       61 taaatttttt taaatgatat actgttttta tggagagata acaattatat ataaatgtac
      121 tactctattt cctagataat acttagtaaa actttttata acaaaggcta gcaaagttaa
      181 agtttattat ctattggaag ttaaataaat atgtaaggaa ttaaaatgaa aaaaagtaca
      241 gtattgtcat taaccacagc tgcagttatt ttagcagcct atgcccctaa tgaggtagtc
      301 ttagcagaca catctagctc tgaagatgct ttaaacatct ctgataaaga aaaagtagta
      361 ttagataagg aaacagaaaa taaagagaaa catgaagata ttcataatgc tatagaaact
      421 tcaaaggata ctgaagaaaa gaaaacaaca gttattgagg aaaaagaagt tgttagtaaa
      481 aatcctgtga tagacactaa aactagcaat gaagaagcaa gaatcaaaga agattccaat
      541 caatcccaag gagataatgc acactcgtct gcaaataaag gcacagaaaa tccgaaaaaa
      601 gaagatagac ttgtctatat tgctgaattt aaagataaag aatctggaga aaaagcaatc
      661 aagcaactat ccaatcttaa gaatacaaaa gttttatata cttatgatag aatttttaac
      721 ggtagtgcca tagaaacaac tccagataac ttggacaaaa ttaaacaaat agaaggtatt
      781 acatcggttg aaagggcaca aaaagtccaa cccatgatga atcatgccag aaaggaaatt
      841 ggagttgagg aagctattga ttacctaaag tctatcaatg ctccgtttgg gaaaaatttt
      901 gatggtagag gtatggtcat ttcaaatatc gatactggaa cagattatag acataaggct
      961 atgagaatcg atgatgatgc caaagcctca atgagattta aaaaagaaga cttaaaagga
     1021 actgataaaa attattggtt gagtgataaa atccctcatg cgttcaatta ttataatggt
     1081 ggcaaaatca ctgtagaaaa atatgatgat ggaagggatt attttgaccc acatgggatg
     1141 catattgcag ggattcttgc tggaaatgat actgaacaag atatcaaaaa ctttaacggc
     1201 atagatggaa ttgcacctaa tgcacaaatt ttctcttaca aaatgtattc tgacgcagga
     1261 tctgggtttg cgggtgatga aacaatgttt catgctattg aagattctat caaacacaac
     1321 gttgatgttg tttcggtatc atctggtttt acaggaacag gtcttgtagg tgagaaatat
     1381 tggcaagcta ttcgggcatt aagaaaagca ggcattccaa tggttgtcgc tacgggtaac
     1441 tatgcgactt ctgcttcaag ttcttcatgg gatttagtag caaataatca tctgaaaatg
     1501 accgacactg gaaatgtaac acgaactgca gcacatgagg atgcgatagc ggtcgcttct
     1561 gctaaaaatc aaacagttga gtttgataaa gttaacatag gtggagaaag ttttaaatac
     1621 agaaatatag gggccttttt cgataagaat aaaatcacaa caaatgaaga tggaacaaaa
     1681 gctcctagta aattaaaatt tgtatatata ggcaaggggc aagaccaaga tttgataggt
     1741 ttggatctta ggggcaaaat tgcagtaatg gatagaattt atacaaagga tttaaaaaat
     1801 gcttttaaaa aagctatgga taagggtgca cgcgccatta tggttgtaaa tactgtaaat
     1861 tactacaata gagataattg gacagagctt ccagctatgg gatatgaagc ggatgaaggt
     1921 actaaaagtc aagtgttttc aatttcagga gatgatggtg taaagctatg gaacatgatt
     1981 aatcctaata aaaaaactga agtcaaaaga aataataaag aagattttaa agataaattg
     2041 gagcaatact atccaattga tatggaaagt tttaattcca acaaaccgaa tgtaggtgac
     2101 gaaaaagaga ttgactttaa gtttgcacct gacacagaca aagaactcta taaagaagat
     2161 atcatcgttc cagcaggatc tacatcttgg gggccaagaa tagatttact tttaaaaccc
     2221 gatgtttcag cacctggtaa aaatattaaa tccacgctta atgttattaa tggcaaatca
     2281 acttatggct atatgtcagg aactagtatg gcgactccaa tcgtggcagc ttctactgtt
     2341 ttgattagac cgaaattaaa ggaaatgctt gaaagacctg tattgaaaaa tcttaaggga
     2401 gatgacaaaa tagatcttac aagtcttaca aaaattgccc tacaaaatac tgcgcgacct
     2461 atgatggatg caacttcttg gaaagaaaaa agtcaatact ttgcatcacc tagacaacag
     2521 ggagcaggcc taattaatgt ggccaatgct ttgagaaatg aagttgtagc aactttcaaa
     2581 aacacggatt ctaaaggttt ggtaaactca tatggttcca tttctcttaa agaaataaaa
     2641 ggtgataaaa aatactttac aatcaagctt cacaatacat caaacagacc tttgactttt
     2701 aaagtttcag catcagcgat aactacagat tctctaactg acagattaaa acttgatgaa
     2761 acatataaag atgaaaaatc tccagatggt aagcaaattg ttccagaaat tcacccagaa
     2821 aaagtcaaag gagcaaatat cacatttgag catgatactt tcactatagg cgcaaattct
     2881 agctttgatt tgaatgcggt tataaatgtt ggagaggcca aaaacaaaaa taaatttgta
     2941 gaatcattta ttcattttga gtcagtggaa gaaatggaag ctctaaactc caacgggaag
     3001 aaaataaact tccaaccttc tttgtcgatg cctctaatgg gatttgctgg gaattggaac
     3061 cacgaaccaa tccttgataa atgggcttgg gaagaagggt caagatcaaa aacactggga
     3121 ggttatgatg atgatggtaa accgaaaatt ccaggaacct taaataaggg aattggtgga
     3181 gaacatggta tagataaatt taatccagca ggagttatac aaaatagaaa agataaaaat
     3241 acaacatccc tggatcaaaa tccagaatta tttgctttca ataaccaagg gatcaacgct
     3301 ccatcatcaa gtggttctaa gattgctaac atttatcctt tagattcaaa tggaaatcct
     3361 caagatgctc aacttgaaag aggattaaca ccttctccac ttgtattaag aagtgcagaa
     3421 gaaggattga tttcaatagt aaatacaaat aaagagggag aaaatcaaag agacttaaaa
     3481 gtcatttcga gagaacactt tattagagga attttaaatt ctaaaagcaa tgatgcaaag
     3541 ggaatcaaat catctaaact aaaagtttgg ggtgacttga agtgggatgg actcatctat
     3601 aatcctagag gtagagaaga aaatgcacca gaaagtaagg ataatcaaga tcctgctact
     3661 aagataagag gtcaatttga accgattgca gaaggtcaat atttctataa atttaaatat
     3721 agattaacta aagattaccc atggcaggtt tcctatattc ctgtaaaaat tgataacacc
     3781 gcccctaaga ttgtttcggt tgatttttca aatcctgaaa aaattaagtt gattacaaag
     3841 gatacttatc ataaggtaaa agatcagtat aagaatgaaa cgctattcgc gagagatcaa
     3901 aaagaacatc ctgaaaaatt tgacgagatt gcgaacgaag tttggtatgc tggcgccgct
     3961 cttgttaatg aagatggaga ggttgaaaaa aatcttgaag taacttacgc aggtgagggt
     4021 caaggaagaa atagaaaact tgataaagac ggaaatacca tttatgaaat taaaggtgcg
     4081 ggagatttaa ggggaaaaat cattgaagtc attgcattag atggttctag caatttcaca
     4141 aagattcata gaattaaatt tgctaatcag gctgatgaaa aggggatgat ttcctattat
     4201 ctagtagatc ctgatcaaga ttcatctaaa tatcaaaagc ttggcgagat tgcagaatct
     4261 aaatttaaaa atttaggaaa tggaaaagag ggtagtctaa aaaaagatac aactggggta
     4321 gaacatcatc atcaagaaaa tgaagagtct attaaagaaa aatctagttt tactattgat
     4381 agaaatattt caacaattag agactttgaa aataaagact taaagaaact cattaaaaag
     4441 aaatttagag aagttgatga ttttacaagt gaaactggta agagaataga ggaatacgat
     4501 tataaatacg atgataaggg aaatattatt gcttatgacg atggtagtgc cttacaatat
     4561 gaaactgaaa aacttgacga aataaaatca aaaatttatg gcgttctaag cccatctaaa
     4621 gatggacact ttgaaattct tggaaagata agcaatgttt ctaaaaatgc caaggtatat
     4681 tatggaaata gctataaatc gatagaaatc aaagcgacta agtatgactc acattcaaaa
     4741 acgatgacat ttgatttata cgctaatatt aatgatattg tggatggatt agcttttgct
     4801 ggagatatgc ggttttttgt taaagatgat aatcgaataa aagctgaaac taaaattaga
     4861 atgcctgaaa aaaataagga aactaaagca gaatatccct atgtatcaag ttatgggaat
     4921 gtaatcgaat taggagaagg agatctttca aagaacaaac cagacaattt aactaaaatg
     4981 gaatctggta aaatctattc tgattcagaa aaacaacaat atctgttaaa ggataacatc
     5041 attctaagaa aaggctatgc actaaaagtg actacctata atcctggaaa aacggatatg
     5101 ttagaaggaa atggagtcta tagcaaggaa gatatagcaa aaatacaaaa ggccaatcct
     5161 aatctaagag tcctttcaga aacaacaatt tatgctgata gtagaaatgt tgaagatgga
     5221 agaagtaccc aagctgtatt aatgtcggct ttggacggct ttaacattat aaggtatcaa
     5281 gtgtttacat ttaaaatgaa cgataaaggg gaagctatcg ataaagacgg aaatcttgtg
     5341 acagattctt ctaaacttgt attatttggt aaggatgata aagaatacac tggagaggat
     5401 aagtccaatg tagaagctat aaaagaagat ggctccatgt tatttattga taccaaacca
     5461 gtaaaccttt caatggataa gaactacttt aatccatcta aatctaataa aatttatgta
     5521 cgaaatccag aattttattt aagaggtaag atttctgata agggtggttt taactgggaa
     5581 ttgagagtta atgaatcggt tgtagataat tatttaatct acggagattt acacattgat
     5641 aacactagag attttaatat taagctgaat gttaaagacg gtgacatcat ggactgggga
     5701 atgaaagact ataaagcaaa cggatttcca gataaggtaa cagatatgga tggaaatgtt
     5761 tatcttcaaa ctggctatag cgatttgaat gctaaagcag ttggagtcca ctatcagttt
     5821 ttatatgata atgttaaacc cgaagtaaac attgatccta agggaaatac tagtatcgaa
     5881 tatgctgatg gaaaatctgt agtctttaac atcaatgata aaagaaataa tggattcgat
     5941 ggtgagattc aagaacaaca tatttatgta aatggaaaag aatatacatc atttgatgat
     6001 attaaacaaa taacagacaa gacactaaac attaagattg ttgtaaaaga ttttgcaaga
     6061 aatacaaccg taaaagaatt cattttaaat aaagatacgg gagaggtaag tgaattaaaa
     6121 cctcataggg taactgtgac cattcaaaat ggaaaagaaa tgagttcaac gatagtgtcg
     6181 gaagaagatt ttattttacc tgtttataag ggtgaattag aaaaaggata ccaatttgat
     6241 ggttgggaaa tttctggttt cgaaggtaaa aaagacgctg gctatgttat taatctatca
     6301 aaagatacct ttataaaacc tgtattcaag aaaatagagg agaaaaagga ggaagaaaat
     6361 aaacctactt ttgatgtatc gaaaaagaaa gataacccac aagtaaacca tagtcaatta
     6421 aatgaaagtc acagaaaaga ggatttacaa agagaagatc attcacaaaa atctgattca
     6481 actaaggatg ttacagctac agttcttgat aaaaacaata tcagtagtaa atcaactact
     6541 aacaatccta ataagttgcc aaaaactgga acagcaagcg gagcccagac actattagct
     6601 gccggaataa tgtttatagt aggaattttt cttggattga agaaaaaaaa tcaagattaa
     6661 gacaaaagct atagaaaaaa atggtttatg tactgagatt agatagtgag gtgatgacat
     6721 agttttgtga aaacggccat ttataactca attatttagt ttacttcact tcactattga
     6781 tactatttgg agttattaat ggacttagtt tagataacta atgaattgat tgaaagggtt
     6841 agtattgaca atattggtca tattgattag aaaatagagt ctatcaaaat ttaaaggcta
     6901 atagaggtga tgagacaatt tcaaggaatt aagtagcgtt tggttgctta attccttttt
     6961 atttggaagg aagtttttcg taaccgccca ataacgaagt ctattggacg gttacgatat
     7021 gatcactgac ttcgtcagtc ttatctacaa cctcaaaact gtgttttgag caacctgcgg
     7081 ctagcttcct agtttactct ttgattttca ttgagtatta gaacagaaaa aatgcttgga
     7141 gtatttgttt gtgtgtttat ttttatataa caaactataa acaaaacaaa aatataaaaa
     7201 aagagacaaa aaagaacaaa aagtaattga caacggtttc atatagtgtt atacttatgg
     7261 cataaagtta atggaaagaa gggaaaaact tatggtatta gattatttct ttgacaaaaa
     7321 ccttgtgttt tgcttagaag cggataatca agaacatctc tttgatcagg ttgcaacttt
     7381 attggaagaa cgagaaattg taactccaac ttatcgtgaa gccttgatca cgcgtgaaaa
     7441 gtcatttcca actggtttag atatggaatt tctaggaaag gacttgccaa atgtagcgat
     7501 tcctcacaca gatattgttc ataatctagc tgagaaagtg gtggttgttc gattagaaaa
     7561 accagtaact tttcacaata tgatagctcc tgataaggaa gtagaagtat ctctactctt
     7621 ctttatcatt aacaattcaa gttcaagtca aacgaacatt ctggctcagt tgatggactt
     7681 tttcacagga aatggtcatc ttgaagacct atcaaaaatt tctgaaccag aaaaacttta
     7741 tgcttacatt gctgaagcaa ccgcttaatc ttgtctatta aaaaataaaa tcggaggaaa
     7801 tccaaatgat taaaattctt gctgcctgcg gtgcaggtgt taactcaagt caccaaatta
     7861 aaagtgctct agaagaagaa ctttcaaacc gtggttatga tgttcactgt gatgcagtca
     7921 tggtgaaaga tgtaaacgaa gaccttatga aaggttacga tatctttaca ccaatcgctg
     7981 caacagacct tggttttgaa ccaggtatcc cagttatcga agctgggcca atcttattcc
     8041 gtatcccagc aatgagcgct ccagtatttg acaatattga agcagctatt aaagaacatg
     8101 gattaagcta attctaattt gttaacattc atataacata aaaaagggag gaactgttat
     8161 ggatgcaatc tttgacctaa tcggaaaggt tttcaatccc atcttagaaa tgggtggacc
     8221 tgtcatcatg ttgatcattt tgacagtatt ggctttactt tttggagtga aattctccaa
     8281 agcgcttgaa ggtggtatca aacttgccat cgctcttaca ggtatcggtg ctatcatcgg
     8341 tatgctaaat ggtgctttct cagcatcact tgcaaaattc gttgaaaaca ctggtatcca
     8401 attgagtatt acagacgttg gttgggcacc actcgcaaca atcacttggg gttctgcttg
     8461 gacactatac ttcttgctca tcatgttgat tgtcaacgta gtgatgcttg ctatgaagaa
     8521 aaccgataca cttgatgtcg atatctttga tatctggcac ttgtctatca caggtctctt
     8581 gattaaatgg tatgctgata acaatggtgt gagtcaagag gtttcactct ttattgctac
     8641 agcagctatc gtccttgtcg gtgtgttgaa aattatcaac tctgacttga tgaaacctac
     8701 atttgatgac cttcttaacg ccccaagttc atcaccaatg acatcaactc acatgaacta
     8761 catgatgaac ccagttatca tggttttgga taagattttt gaaaaattct tcccaggcct
     8821 tgataaatat gactttgatg ctgctaaatt gaacaagaaa atcggtttct ggggatctaa
     8881 attcttcatc ggtttcatcc ttggtatcgt tatcggtatt atgggaactc cacatccaat
     8941 tgcaggtgtt gcagatgcag ataaatggcg tcttgttatc aaaggatggt tgtctcttgg
     9001 tttgactgcc ggtgtatctt tggaactctt ctcacttatc ggttcatggt tcatcgcagc
     9061 cgtagaacca ctatcacaag gtattacaaa cgttgctact aaacgtcttc gaggacgtaa
     9121 attcaatatc ggtcttgact ggccattcat cgctggtcgt gctgaaatct gggcttgtgc
     9181 caacgtactt gcaccaatca tgttgattga agcagtgctt ctttcaaaag ttggaaatgg
     9241 tatcttgcca cttgcaggta tcatcgctat gggtgttact ccagctctct tggttgtaac
     9301 tcgtggtaaa ttgctccgta tgattatctt cggaacactc ttgttgccac tcttccttct
     9361 ttcaggtaca cttattgcac catttgcaac agaacttgct aaaggtgtag gtgccttccc
     9421 agaaggtgtg agccaaactc aattgattac tcactctact cttgaaggac caatcgaaaa
     9481 acttcttggt tggacaattg gtaacactac aactggtgat atcaaagcaa tccttggtgc
     9541 agtagtcttc cttgtattct atatcggtat ctttgcttgg tacagaaaac aaatgatcaa
     9601 acgtaacgaa gagtacgcag caaaagcaaa ataatgcgct cctataaaat ataaactcaa
     9661 tgaaaatcaa agagcaaact aggaaactag ccgcaggttg ctaaaaacac agttttgagg
     9721 ttgtagataa gactgacgaa gtcagctcaa aacatggttt tgaggttgta gatgaaactg
     9781 acgaagtcag ctcaaaacat ggttttgagg ttgtagatga aactgacgaa gtcagtaatc
     9841 atatctacgg caaggcgacg ctgacgaagt ttgaattgga ttttcgcaga gtgtaaattg
     9901 ttgaaactag gttgtcatac catgtatacc acttgggctt tggtagtagc taactgcact
     9961 aaatataata taaggagggt tttatgggga aaggccattg gaatcggaaa agagtttata
    10021 gcattcgtaa gtttgctgtg ggagcttgct cagtaatgat tgggacttgt gcagttctat
    10081 taggaggaaa tatagctgga gaatctgtag tttatgcgga tgaaacactt attactcata
    10141 ctgctgagaa acctaaagag gaaaaaatga tagtagaaga aaaggctgat aaagctttgg
    10201 aaactaaaaa tgtagttgaa aggacagaac aaagtgaacc tagttcaact gaggctattg
    10261 catctgagaa gaaagaagat gaagccgtaa ctccaaaaga ggaaaaagtg tctgctaaac
    10321 cggaagaaaa agctccaagg atagaatcac aagcttcaag tcaagaaaaa ccgctcaagg
    10381 aagatgctaa agctgtaaca aatgaagaaa tgaatcaaat gattgaagac aggaaagtgg
    10441 attttaatca aaattggcac tttaaactca atgcaaattc taaggaagcc attaaacctg
    10501 atgcagacgt atctacgtgg aaaaaattag atttaccgta tgactggagt atctttaaca
    10561 atttcgatca tgaatctcct gcacaaaatg aaggtggaca actcaacggt ggggaagctt
    10621 ggtatcgcaa gactttcaaa ctagatgaaa aagacctcaa gaaaaatgtt cgccttactt
    10681 ttgatggcgt ctacatggat tctcaagttt atgtcaatgg tcagttagtg gggcattatc
    10741 caaatggtta taaccagttc tcatatgata tcaccaaata ccttcacaaa gatggtcgtg
    10801 agaatgtgat tgctgtccat gcagtcaaca aacagccaag tagccgttgg tattcaggaa
    10861 gtggtatcta tcgtgatgtg actttacaag tgacagataa ggtgcatgtt gagaaaaatg
    10921 ggacaactat tttaacacca aaacttgaag aacaacaaca tggcaaggtt gaaactcatg
    10981 tgaccagcaa aatcgtcaat acggacgaca aagaccatga acttgtagcc gaatatcaaa
    11041 tcgttgaacg aggtggtcat gctgtaacag gcttagttcg tacagcgagt cgtaccttaa
    11101 aagcacatga atcaacaagc ctagatgcga ttttagaagt tgaaagacca aaactctgga
    11161 ccgttttaaa tgacaaacct gccttgtacg aattgattac gcgtgtttac cgtgacggtc
    11221 aattggttga tgctaagaag gatttgtttg gttaccgtta ctatcactgg actccaaatg
    11281 aaggtttctc tttgaatggt gaacgtatta aattccatgg agtatccttg caccacgacc
    11341 atggggcgct tggagcagaa gaaaactata aagcagaata tcgccgtctc aaacaaatga
    11401 aggagatggg agttaactct atccgtacaa cccacaaccc tgctagtgag caaaccttgc
    11461 aaatcgcagc agaactaggt ttactcgttc aggaagaggc ctttgatacg tggtatggtg
    11521 gcaagaaacc ttatgactat ggacgtttct ttgaaaaaga tgccactcac ccagaagctc
    11581 gaaaaggtga aaaatggtct gattttgacc tacgtaccat ggtcgaaaga ggcaaaaaca
    11641 accctgctat cttcatgtgg tcaattggta atgaaatagg tgaagctaat ggtgatgccc
    11701 actctttagc aactgttaaa cgtttggtca aggttatcaa ggatgttgat aagactcgct
    11761 atgttaccat gggagcagat aaattccgtt tcggcaatgg tagcggaggg catgagaaaa
    11821 ttgctgatga actcgatgct gttggattta actattctga agataattac aaagccctta
    11881 gagctaagca tccaaaatgg ttgatttacg gttcagaaac atcatcagca acccgtacac
    11941 gaggaagtta ctatcgccct gaacgtgaat tgaaacatag caatggacct gagcgtaatt
    12001 atgaacagtc agattatgga aatgatcgtg tgggttgggg gaaaacagca accgcttcat
    12061 ggacttttga ccgtgacaac gctggctatg ctggacagtt tatctggaca ggtacggact
    12121 atattggtga acctacacca tggcacaacc aaaatcaaac tcctgttaag agctcttact
    12181 ttggtatcgt agatacagcc ggcattccaa aacatgactt ctatctctac caaagccaat
    12241 gggtttctgt taagaagaaa ccgatggtac accttcttcc tcactggaac tgggaaaaca
    12301 aagaattagc atccaaagta gctgactcag aaggtaagat tccagttcgt gcttattcga
    12361 atgcttctag tgtagaattg ttcttgaatg gaaaatctct tggtcttaag actttcaata
    12421 aaaaacaaac cagcgatggg cggacttacc aagaaggtgc aaatgctaat gaactttatc
    12481 ttgaatggaa agttgcctat caaccaggta ccttggaagc aattgctcgt gatgaatctg
    12541 gcaaggaaat tgctcgagat aagattacga ctgctggtaa gccagcggca gttcgtctta
    12601 ttaaggaaga ccatgcgatt gcagcagatg gaaaagactt gacttacatc tactatgaaa
    12661 ttgttgacag ccaggggaat gtggttccaa ctgctaataa tctggttcgc ttccaattgc
    12721 atggccaagg tcaactggtc ggtgtagata acggagaaca agccagccgt gaacgctata
    12781 aggcgcaagc agatggttct tggattcgta aagcatttaa tggtaaaggt gttgccattg
    12841 tcaaatcaac tgaacaagca gggaaattca cccttactgc tcactctgat ctcttgaaat
    12901 ctagtcaagt cactgtcttt actggtaaga aagaaggaca agaaaagact gttttgggga
    12961 cagaggtgcc aaaagtacag accattattg gagaggcacc tgaaatgcct accactgttc
    13021 cgtttctata cagtgatggt agtcgtgcag aacgtcctgt aacctggtct tcagtagatg
    13081 tgagcaagcc tggtattgta acggtgaaag gtatggctga cggacgagaa gtagaagctc
    13141 gtgtagaagt gattgctctt aaatcagagc taccagttgt gaaacgtatt gctccaaata
    13201 ctgacttgaa ttctgtagac aaatctgttt cctatgtttt gactgatgga agtgtacaag
    13261 agtacgaagt agatagctgg gagattacgg aagtagataa agccaaactt tcagtagctg
    13321 gatcacgtat tcaaatgact ggtcagttag ctggagaaac tattcatgca acccttgtgg
    13381 tagaagaagg aaatgctgca gcacctgtag tgccaactgt tactgttgga ggtgaagcag
    13441 taacaggtct tactagtcga caaccaatgc aatatcgtac tctatcttat ggtgcccaat
    13501 tgccagaagt cacagcaagt gctgaaaatg ctgatgtgac agttcttcaa gcaagcgcag
    13561 caaacggcat gcgtgcaagc atatttgttc agcctaaaga tggtggccct cttcaaacct
    13621 atgcaattca attcctagaa gaagcaccaa aaattgctca cttgagcttg caagtggaaa
    13681 aagctgacag tctcaaagaa gaccaaactg tcaaattgtc ggttcgagct cactatcaag
    13741 atggaacgca agctgtatta ccagctgata aagtaacctt ctctacaagt ggtgaagggg
    13801 aagtcgcaat tcgtaaagga atgcttgagt tgcataagcc aggagcagtc actctcaaag
    13861 cggaatatga gggagctaaa ggccaagttg aactcactat ccaagccaat actgagaaga
    13921 agattgcgca atctatccgt cctgtaaatg tagtcacaga tttgcatcaa aaacctactc
    13981 ttccaacaac agtaacggtt gagtatgaca aaggtttccc taaagctcac aaagtcactt
    14041 ggcaagctat tccgaaagaa aaactagact cctatcaaac atttgaagta ctaggtaaag
    14101 ttgaaggaat tgaccttgaa gcgcgtgcaa aagtctctgt agaaggtatc gtttcagttg
    14161 aagaagtcag tgtgacaact ccaatcgcag aagcaccaca attaccagaa agtgttcgga
    14221 catatgattc aaatggtcac gtttcatcag ctaaggttgc atgggatgcg attcgtccag
    14281 agcaatacgc taaggaaggt gtctttacag ttaatggtcg cttagaaggt actcaattaa
    14341 caactaaact tcatgttcgc gtatctgctc aaactgagca aggtgcaaac atttctgacc
    14401 aatggaccgg ttcagaattg ccacttgcct ttgcttcaga ctcaaatcca agcgacccag
    14461 tttcaaatgt taatgacaag ctcatttcct acaataacca accagccaat cgttggacaa
    14521 actggaatcg tactaatcca gaagcttcag tcggtgtcct attcggagat tcaggtattt
    14581 tgagcaaacg ttcagttgat aacttaagcg ttggcttcca tgaagaccat ggagttggtg
    14641 caccgaagtc ttatgtgatt gagtattatg ttggtaagac tgtcccaaca gctcctaaaa
    14701 accctagttt tgttggtaat gaggaccatg tctttaatga ttctgccaac tggaaaccag
    14761 ttactaatct aaaagcccct gctcaactca aggctggaga aatgaaccac tttagctttg
    14821 ataaagttga aacctatgct gttcgtattc gcatggtgag agcagacaac aaactaggaa
    14881 cgtctatcac agaggtacaa atctttgcga aacaagttgc ggcagccaag caaggacaaa
    14941 caagaatcca agttgacggt aaagacttag caaacttcaa ccctgatttg acagactact
    15001 accttgagtc tgtagatgga aaagttacgg cagtcacagc aagtgttagc aacaatggcc
    15061 tcgctaccgt cgttccaagc gttcgtgaag gtgagccggt tcgtgtcatc gcgaaagctg
    15121 aaaatggcga catcttagga gaataccgtc tgcacttcac taaggataag aacttacttt
    15181 ctcataaacc agttgctgcg gttaaacaag ctcgcttgct acaagtaggt caagcacttg
    15241 aattgccgac taaggttcca gtttacttca caggtaaaga cggctacgaa acaaaaaacc
    15301 tgacagttga atgggaagaa gttccagcgg aaaatctgat aaaagcaggt caatttaccg
    15361 ttcgaggcca tgtccttggt agtgatcttg ttgctgaggt cactgtacga gtgacagaca
    15421 aactaggcga agctctttca gataacccta actatgatga aaacagtaac caggcctttg
    15481 cttcagcaac caatgatatt gacaaaaact ctcatgaccg cgttgactat ctcaatgacg
    15541 gagatcattc agaaaatcgt cgttggacaa actggtctcc aacaccatct tctaatccag
    15601 aagtatcagc gggtgtgatc ttccgtgaaa atggtaagat tgtagaacgg actgttgctc
    15661 aagccaaact tcacttcttt gcagatagtg gtacggatgc accaactaaa ctcgttttag
    15721 aacgctatgt cggtccagag tttgaagtgc caacctacta ttcaaactac caagcctacg
    15781 acgcagacca tccattcaac aatccagaaa attgggaagc tgtgccttat cgtgcggata
    15841 aagacatcgc agctggtgat gaaatcaacg taacatttaa agctgtcaaa gccaaagcta
    15901 tgagatggcg tatggagcgt aaagcagata agagcggtgt tgcgatgatt gagatgacct
    15961 tccttgcacc aagtgaattg cctcaagaaa gcacgcaatc gaagattctt gtagatggaa
    16021 aagaacttgc tgatttcgct gaaaatcgtc aagactatca aattacctat aaaggtcaac
    16081 ggccaaaagt ctcagttgaa gaaaacaatc aagtagcttc aactgtggta gatagtggag
    16141 aagatagcct tccagtactt gttcgcctcg tttcagaaag tggaaaacaa gtcaaggaat
    16201 accgtatcca gttgactaag gaaaaaccag tttctgagaa gacagttgct gctgtacaag
    16261 aagatcttcc aaaactcgaa tttgttgaaa aagatttggc ctacaagaca gttgagaaaa
    16321 aagattcaac actgtatcta ggtgaaactc gtgtagaaca agaaggaaaa actggtaaag
    16381 aacgtatctt tacagcgatt aatcctgatg gaagtaagga agaaaaactc cgtgaagtgg
    16441 tagaagctcc gacagaccgc atcgtcttgg ttggaaccaa accagtagct caagaagcta
    16501 aaaaaccaca agtgtcagaa aaagcagata caaaaccaat tgattcaagt gaagctagtc
    16561 aaactaataa agcccagtta ccaaatacag gtagtgcggc aagccaagca gcagtagcag
    16621 caggtttagc tcttctaggt ttgagtgcag gattagtagt tactaaaggt aaaaaagaag
    16681 actagaaatt ttgatacctt ctttatcatt aaagaccaaa gaaaaactct tgtcctaaat
    16741 agaagataaa gagtctggaa caaaatagtt ctcaaccaca aaaaagctag atatttccaa
    16801 ttgcggaact ctagcttttt aattttgagt cgttctctta ttgtatagta gattgaaact
    16861 agagtagtac acttctactt ctaaaacatt gttagaaatc gatttgactg tccttatcga
    16921 tttgtcctgt tcttatttca tttcactatg ttttaggagg ttattggcca taagtaccaa
    16981 tcccatgtca attctcactt gacgcttgcc tctcagatta catctcttgt aacccaaaca
    17041 agcctttatc tgcccaaaga caggttctac atcaatcttg cgttgagcga aaatctgtct
    17101 atcttgggga gataaaagcg cctgacattc tttagctttc aagttttgat agcgttcgtt
    17161 catatacaat cccttttgag gggctgattc aggttcatca gcgtagtaaa ccttgatttc
    17221 ctgttgaaag tctgtctgtg ttttctggta cttgatatgg tgaaaacgat agcaccagcc
    17281 atcaggatgt atgtagctat cctccttgtc attatagtgc caattcgcta agtttttagc
    17341 tgactgttta taccctctct tttgttcctt atcaaacatg gcatatttaa tcagaagggg
    17401 agtgatttct tcttgaaaat agacttgtat ctgttcttga agtttggcgg agaatttctc
    17461 tgtcgttttc ttccacacaa aactatactt gttggcattg gattcaatct tagttccgtc
    17521 aataaacaaa caatctaagg tcactaactc ttccattttt caatttttcg accagagaaa
    17581 atcccttgtg aataggcaaa tagaagagta gatacaagca ttttagggtg ataagacggg
    17641 cgaccaaagg catgatagga ggtgtagaag tgacgttcct ccaaggtatt caccactttt
    17701 tcaatagtaa agacgagatg gtcttgtggt aagaaggaac tgatttctag tggtaaagtt
    17761 gtttgatttg tgttatagtg aatatgcatg ggatagcctt tctaaatggt ttattaagca
    17821 attctatttt accaagacta tcgtaaccat gcaaaaaagc aacggcaaat ccgttgcctt
    17881 ttttggatat aagagactat tgtcccagac tcttttcttt gtataaaatt gtatagtgtt
    17941 attgtctata ctattttgta gagaaagcaa aaatccctag aaaatgctta gggattcgac
    18001 tatttcatta agaacaattc aacaatcatc tctatataca tgataagggt taataaaaat
    18061 cctgtacgcc agaagaattt gatgaattta ggatagtaaa agctgcgttt ttttaaaagg
    18121 aagaaaaaga cgagaataat ggctaggaac gagagggcta gccccagtct agggaggaaa
    18181 ttatgggtaa aggttttagc tgtaatcaag taatactcaa ataccaagac tggaaaagcc
    18241 aaatccgcaa agtttcgtcc tagttttttt aatctaaaaa gtttggttag gataatgcag
    18301 acgactaagg tcagtatcaa taataaaata gatgctaatt tcattaaaat catacccata
    18361 ttgtatcata aaaaaaggct aatggaaacg agaaacagag gaatttatag gaaagtcagg
    18421 cttttgagat tgtgggtgat ttttgttata atgaaagtta taaaatctta tgataccttg
    18481 aatgattatt atcgaaaact ctttggagaa aagactttta aagtccctat tgatgcggga
    18541 tttgactgtc ccaatcgtga tggaactgtg gctcatggag gctgtacttt ttgtacggtt
    18601 tccggttctg gagatgccat tgtagcccca gatccgccta tccgtgagca attttataag
    18661 gaaattgact ttattcatcg taagtggcca gatgttcaga agtatctggt ttattttcaa
    18721 aattttacca acacccatga aaaggtggaa gttattcgag agcgttatga acaggctatc
    18781 aatgagccag gtgtggtagg aatcaatatt ggaacgcgcc cagactgttt accagacgaa
    18841 accatcgaat atttggctga gttatcggag tgcatgcatg tgacggttga attgggcttg
    18901 cagactactt atgaagcaac ctctgacctg attaaccgtg cgcattctta tgaattgtag
    18961 gtggaaacgg tcaagcgttt gagaaagtat ccaaaaattg agattgtttc ccatttgatc
    19021 aatggtttgc ctggtgaaac ccatgagatg atggttgaaa atgtccgccg ttgtgtcacg
    19081 gataacgata ttcaagggat taaactgcat ttgctccatc ttatgacaaa tactcgtatg
    19141 caacgagatt accatgaggg acgtttacaa ttgatgagtc aggacgaata tgtcagggtc
    19201 atctgtgacc aactggaaat tattcccaaa catatcgtca tccatcgaat tacaggagat
    19261 gcgcctaggg atatgctgat tggtcctatg tggagcctca ataaatggga agtcctcaac
    19321 agcattgaga tggagatgag acgtcgtgga agtgttcaag gatgcaaggc tgtaaaacag
    19381 gagtttgaaa atgaaaagac cacttgagat ggcacatgat tttttggctg aggtcgtgac
    19441 aaaagaggat gtcgtagtgg atgcgactat gggaaatggt catgacacgc tttttttagc
    19501 caagctagcc aagcaagtct atgcctttga tattcagaag caagccttgg aaaagaccca
    19561 agagcgtttg catcaggctg gcttgacaaa tgcccagtta atcttgcaag gccatgagac
    19621 actggaccag tttgtgacaa aagctaaggc agggattttt aatttgggct atttgccgtc
    19681 agctgataag tctgtcatca cccgaccgca gacaacgatt gaggcattag aaaagctatg
    19741 tggcttactt gtcaaaggtg gacgaattgc tattatgatt tactatggtc atgaaggagg
    19801 cgacctcgag agagatgctg tcttggattt tgtgatccag ttgaaccaac aagagtacac
    19861 agctgccatt taccgaactt taaaccaagt caacaacccg ccgtttttag tgatgattga
    19921 aaaattagag agatacagac atggataaac aatacctaca cgaaaagctg gatgccatgc
    19981 gccagaattt tgttgaatca acctaccacg aacgagcggt gggcgtgcta gaccaagcgc
    20041 atatgagcaa aaaaatgctt aaaatcaaga aaaaattagt tgctcttgaa atggaacggt
    20101 gccagagaaa aattgagcac aaagactgtt ccaagattga ccaaaaaatc aaagagcaga
    20161 aggagatatt tgaatcctgt tgtaaaaaag attaaggagg acgtgcgtgg aattactgat
    20221 ttacctcatc ctatttttac tggtcttgat tgtctcaagt acaaccaata agctcctacc
    20281 ctttttgcct ctccctttgg tgcagattct tttgggaatt gtgattggtc tctttttacc
    20341 caatactgac tttcacctta atacggagtt gtttttggca ctggttatcg gccccttgct
    20401 tttccgagag gctgaagaag cagatgttac ggctatttta aaacactggc gaatcattgt
    20461 ttatctcata tttccagtga tttttatctc gaccctgagt ttgggtggct tggcccatct
    20521 tctttggttc agccttccct tggcagcttg cttggctgtt ggggcagccc ttggtcctac
    20581 ggacttggtg gcctttgcct ctctttcgga gcgttttagc tttcctaagc gcgtgtccaa
    20641 tattcttaag ggcgaaggac tcttgaatga tgcttctggt ttggtggctt ttcaggtagc
    20701 tttgacagct tggacaactg gagctttttc tctggggcaa gctagcagtt cactcatctt
    20761 ttcaatccta ggcggttttt taattggatt tttaacagcc atgaccaacc gcttcctcca
    20821 taccttcttg ctaagtgtgc gtgcaacgga tattgccagt gaacttttat tagaattgag
    20881 tttgcctctt gtgaccttct ttctggcaga agaagttcat gtttcaggta ttattgccgt
    20941 cgtagttgct ggaattttaa aggcaagtcg tttcaagaaa atcacgctcc tcgaagccca
    21001 agtggatacg gtgaccgaga cggtctggca tacagtgacc tttatgctca acggttctgt
    21061 ctttgtgatt ttagggatgg agctggaaat gatagcagaa cctatcttga ccaatccaat
    21121 ctataatcct ctacttttat tgctatctct tatcgccctt acctttgtcc tctttgtcat
    21181 tcgttttatt atgatctatg gctattatgc ctatagaacc cgacgcctca agaaaaagct
    21241 aaataagtat atgaaggaca tgtttctctt gaccttttca ggtgttaagg gaacggtgtc
    21301 gattgctacg attctcttga taccaagtaa tctagaacag gagtatcctc tcttgctttt
    21361 ccttgttgca ggtgtgacgc ttgttagctt tttaacaggt ctcttggtct tgcctcatct
    21421 ttctgatgaa gaggaagaaa gcaaggatta tctcatgcat atcgccattt tgaatgaagt
    21481 aacgctagag ttggaaaaag agttggaaga caccagaaat aaactttccc tctatgcggc
    21541 tattgacaat tatcatggac gtattgaaaa tctcatttta agccaagaaa accaggatga
    21601 tcaagaagac tgggctgctt tgaaactctt gattcttagt attgaaagtg atggtttgga
    21661 acaggcctat gaagagggga atattagcaa tcgtgcttac cgagtttacc aacgttatct
    21721 gaaaaatata gaacaaggaa tcaatcgtaa acttgcctca agactgacct attattttct
    21781 tgtttccttg aggattttac gttttctcct tcatgaagtt tttactcttg gaaagacctt
    21841 ccgtagctgg aaggacaagg agcaaagccg tctccgtgct cttgattatg accaaattgc
    21901 agagctctat cttgccaata cagagatgat tattgaaagt ttggaaaacc tgaagggagt
    21961 ctacagacgc tctttgatta gttttatgca ggagtctcgt cttcgagaaa cagctattat
    22021 cagcagtggt gcctttgtcg aacgggttat caatcgtgtc aaacccaaca atatcgatga
    22081 aatgctgaga ggctattatc tggagcgcaa gttgattttc gaatacgaag aaaaacgatt
    22141 aattacaact aagtatgcca agaaattacg acaaaatgta aataacttag agaactattc
    22201 cttgaaggaa gctgccaata ccctgccgta tgatatggtg gaattggtaa gaagaaatta
    22261 gttaatactc ttcgaaaatc tcttcaaacc acgtcagcgt cgccttggat tatatatgtg
    22321 actgacttcg tcagtttcat ctacaacctc aaagcagggc tttgagcaac ctgcggctag
    22381 cttcctagtt tgctctttga ttttcattga gtataagatt ataaatgaag gagtatgaca
    22441 tgaaaaagtg gtggaaagag ctgatagaca agcctttatt aaaagctttt ttgcattatt
    22501 atcaagcatc agatagtgag ttgaccagtg tcgcagtagc ctactattgg ttgatttcga
    22561 ttttccccct gcttttggtg gtggtcaata tcctccccta ttttcagatt cctgtgggag
    22621 aatttctgtg ctttatgaaa gacgttctgc ccccaagcct ctatgaaggt gtggaaaaaa
    22681 tagccagaga agttttgacg caaccttcaa caggtttatt gagtttttct gttttatcgg
    22741 cgttatggag tttttcaaaa tctatgaatt tcttgcaaaa agcttttaac aaggcttatg
    22801 gcgtcgaaaa gagtcgtgga cttatttccc atcagatgct aagtctccta gtcagttttg
    22861 gcttgcagct cctctttgcg tttgccttgt ttttgatctt atttggtcag atgattttgg
    22921 ctttacttgc tcattattgg acaaaagatg gcattatcta tcaggcttta caagggttgg
    22981 caggtcctct gatttacgcc ctcctctttg ctatcttggt catgctttat tattttcttc
    23041 ccaatatatc taacaggaaa attagctata ccctaccagg cagtgccttt gttctcttag
    23101 tgattttagg tttactaact ctgttctcta gttatctcaa ttactatgtc catcatttgg
    23161 tggatgtccg aattttaggt tccgttcttc ttgttgttat gatgttttgg tttatcttga
    23221 ttgctaaaat tgttatccta ggcgcggtta tcaatgccag tatgcagagt ttgagagatc
    23281 cggtctttaa aaaagactaa ctatttatcc attacaaaag cgcatagtat caaaacttta
    23341 tagaaccttg atactatgcg cttttgtgct ttgacagttt tttgtatagt ttttgtccaa
    23401 gatttctaaa tcatctgatt aaattcctat tttcccctat cattgtccct gttttttcga
    23461 aaatggaagg agtataataa atctatcaat aaaatgatag gaggaacttt atgggtcata
    23521 ttttcttttt tctaagtgtc tttttggcag ggattctatc cttcttttct ccttgtatct
    23581 tacctttgtt accggtctat acaggagtgt tactagatga taaggatggt gctcaggctt
    23641 ctagcggcaa attttcaatc tcagttacta gtttattacg aactctggcc tttatagcag
    23701 gaatttcctt tatatttatt ttgttgggct atggagctgg ttttttaggc gatttgcttt
    23761 atgcttcttg gttccaatat cttactgggg caattattat ccttcttggt ttgcaccaaa
    23821 tggagattct acactttaag gggctttata aggaaaagag gctacaactg caaggacagg
    23881 ggcaaaatgg taagggctat agtcaggcat ttttattggg cttgaccttt agttttgctt
    23941 ggacgccttg cgtggggccg gttctggggt ctgttttggc cttggcggct tcaggtggtt
    24001 caggagcttg gcagggagct ggtctcatgt tggtgtatac gctgggcttg gcgctaccat
    24061 tcttgcttct agctctgacc tctagttatg ttttgaaaca tttccgaaaa cttcatccct
    24121 atctcggaat cctcaaaaaa gtgggtggtt ttctcattat tgtgatggga ctcttggttc
    24181 tgtttggaaa tgcttcaatt ttaagtcaat tatttgaata aaatggaaag gaatatcaat
    24241 atgaaaaaat ggcaaacatg tgttcttgga gcaggttcgc tcctttgttt gacggcttgt
    24301 tcaggcaagt ccgtgactag tgaacaccaa acgaaagatg aaatgaagac ggagcagaca
    24361 gctagtaaaa caagcgcagc taaagggaaa gaggtggctg attttgaatt gatgggagta
    24421 gatggcaaga cctaccgttt atctgattac aagggcaaga aagtctatct caaattctgg
    24481 gcttcttggt gttccatctg tctggctagt cttccagata cggatgagat tgctaaagaa
    24541 gctggtgatg actatgtggt cttgacagta gtgtcaccag gacataaggg agagcaatct
    24601 gaagcggact ttaagaattg gtataaggga ttggattata aaaatctccc agtcctagtt
    24661 gacccatcag gcaaactttt ggaaacttat ggtgtccgtt cttacccaac ccaagccttt
    24721 atagacaaag aaggcaagct ggtcaaaaca catccaggat tcatggaaaa agatgcaatt
    24781 ttgcaaactt tgaaggaatt agcctaggag gtgtcttatg aatgataagt taaaaatctt
    24841 cttgttgcta ggagtatttt ttctagccat aaccggtttc tatgttctat tgatacgaaa
    24901 tgcagggcag acagatgcct cgcaaattga aaaggcggca gttagccaag gaggaaaagc
    24961 agtgaaaaaa acagaaatta gtgaagacgc agacttgcac gaaatttatc tagctggagg
    25021 ttgtttctgg ggagtggagg aatatttctc acgcgttccc ggggtgacgg atgccgtttc
    25081 aggctatgca aatggtagag gagaaacaac caagtacgaa ttaattaacc aaacaggtca
    25141 tgcagaaacc gtccatgtca cctatgatgc caagcaaatt tctctcaagg aaatcctgct
    25201 tcactatttc cgcattatca atccaaccag caaaaataaa caaggaaatg atgtggggac
    25261 ccagtaccgt actggtgttt attacacaga tgacaaggat ttggaagtga ttaaccaagt
    25321 ctttgatgag gtggctaaga aatacgatca acctctagca gttgaaaagg aaaacttgaa
    25381 gaattttgtg gtggctgagg attaccatca agactatctc aagaaaaatc caaatggcta
    25441 ctgccatatc aatgttaatc aggcggccta tcctgtcatt gatgccagca aatatccaaa
    25501 accaagtgat gaggaattga aaaagaccct gtcacctgag gagtatgcag ttacccagga
    25561 aaatcaaaca gaacgagctt tctcaaaccg ttactgggat aaatttgaat ccggtatcta
    25621 tgtggatata gcaactgggg aacctctctt ttcatcaaaa gacaaatttg agtctggttg
    25681 tggctggcct agttttaccc aacccatcag tccagatgtt gtcacctaca aggaagataa
    25741 gtcctacaat atgacgcgta tggaagtgcg gagccgagta ggagattctc accttgggca
    25801 tgtctttacg gatggtccac aggacaaggg cggcttacgt tactgtatca atagcctctc
    25861 tatccgcttt attcccaaag accaaatgga agaaaaaggc tacgcttatt tactagatta
    25921 tgttgattaa tactcttcga aaatctcttc aaaccacgtc agcgtcgcct taccgtatgt
    25981 agggttactg acttcgtcag ttttatctac aacctcaaag ctatactttg agctgacttc
    26041 gtcagtttta tctacaacct caaagcggta ctttgagctg acttcgtcag ttttatctac
    26101 aacctcaaag cggtactttg agctgacttc gtcagtttta tctacaacct caaagcggta
    26161 ctttgagaaa cctgtggcta tcttcctagt ttactttttg atttttattg agtataagag
    26221 gtctttccta agcagttaga ggagaatttt gctatactga tactagtaag tggtaaagga
    26281 gcagagcatg acctacacaa tcttaatcgt agaagatgaa tatctggtaa gacaaggttt
    26341 gactaaactg gtcaatgtag cagcctacga tatggaaatc atcggtcagg ctgaaaatgg
    26401 aaggcaggct tgggaattga tccaaaagca ggtgccagat atcattttaa ccgatatcaa
    26461 catgcctcat ctaaatggca tccagttggc cagtctggta cgagaaacct atcctcaggt
    26521 tcatttggtc tttttaacag gttacgatga ttttaattat gccttgtctg ctgtcaaact
    26581 aggtgtggac gactacctgc tcaaaccctt ttctcgtcag gatattgagg aaatgttggg
    26641 gaaaatcaaa caaaaactag acaaggaaga gaaagaagag cagttacaag atttattgac
    26701 taataggttt gaaggaaaca tggcccagaa aatccagtct catctggctg atagccaatt
    26761 tagtttaaag tctttagcca gtgacttagg ttttagtccg acctatctga gttccttgat
    26821 taagaaagag ttgggcttgc cttttcagga ttatctggtg agagaacgtg ttaaacaagc
    26881 caagctcttg cttttaacta cagatctgaa gatttatgag atcgcagaga aggttggttt
    26941 tgaagatatg aactatttta cccaacgttt taagcagatt gcaggtgtga cacctcgtca
    27001 gtttaagaag ggagaagacc gatgaagcgt tcttctcttt tagttagaat ggttatttcc
    27061 atctttctgg tctttctcat tctcctagct ctggttggaa ctttctacta tcaatcaagt
    27121 tcttcagcca ttgaggccac cattgagggc aacagccaaa cgaccatcag ccagactagc
    27181 cactttattc agtcttatat caaaaaacta gaaaccacct cgactggttt gacccagcag
    27241 acggatgttc tggcctatgc tgagaatccc agtcaagaca aggtcgaggg aatccgagat
    27301 ttgtttttga ccatcttgaa gtcagataag gacttgaaaa ctgttgtgct ggtgaccaaa
    27361 tctggtcagg tcatttctac agatgacagt gtgcagatga aaacttcctc tgatatgatg
    27421 gctgaggatt ggtaccaaaa ggccattcat cagggagcta tgcctgtttt gactccagct
    27481 cgtaaatcag atagtcagtg ggtcatttct gtcactcaag aacttgttga tgcaaaggga
    27541 gccaatcttg gtgtgcttcg tttggatatt tcttatgaaa ctctggaagc ctatctcaat
    27601 caactccagt tggggcagca gggctttgcc ttcattatca atgaaaacca tgaatttgtc
    27661 taccatcctc aacacacagt ttatagttcg tctagcaaaa tggaggctat gaaaccctac
    27721 atcgatacag gtcagggtta tactcctggt cacaaatcct acgtcagtca agagaagatt
    27781 gcaggaactg attggacggt gcttggcgtg tcatcattgg aaaagttaga ccaggttcgg
    27841 agtcagctct tgtggacctt gcttggggcc agtgtcacat ctcttcttgt ctgtctctgc
    27901 ttagtgtggt tcagtcttaa acgctggatt gctcctttga aggatttgag agaaaccatg
    27961 ttggaaattg cttctggtgc tcaaaatctt cgtgccaagg aagttggtgc ctatgaactg
    28021 agagaagtaa ctcgccaatt taatgctatg ttggatcaga ttgatcagtt gatggtagct
    28081 attcgtagcc aggaagaaac gacccgtcag taccaacttc aagccctttc gagccagatt
    28141 aatccacatt tcctctataa cactttggac accatcatct ggatggctga atttcatgat
    28201 agtcagcgag tggtgcaggt gaccaagtcc ttggcaacct atttccgctt ggcgctcaat
    28261 caaggcaagg acttgatttg tctctctgac gaaatcaatc atgtccgcca gtatctcttt
    28321 atccagaaac aacgctatgg agataagctg gaatacgaaa ttaatgaaaa tgttgccttt
    28381 gataatttag tcttacccaa gctggtccta caaccccttg tagaaaatgc tctttaccat
    28441 ggcattaagg aaaaggaagg tcagggccat attaaacttt ctgtccagaa acaggattcg
    28501 ggattggtca tccgtattga ggatgatggc gttggcttcc aagatgctgg tgatagtagt
    28561 caaagtcaac tcaaacgtgg gggagttggt cttcaaaatg tcgatcaacg gctcaaactt
    28621 cattttggag ccaattacca tatgaagatt gattctagac cccaaaaagg gacgaaagtt
    28681 gaaatatata taaatagaat agaaactagc taactcccag tcaattctgg gagttttatg
    28741 cgtaattggg caaactttct aggttgtcta tcttgctaaa aacaagaaaa aacggtatga
    28801 tagaagagtg acaacagagg taacagagat gaacgagaca cagattcaaa gagaaacacg
    28861 tcaggtagtg gaagatgttt tagaaaagac caatttgaag cagggggccc tttttgtttt
    28921 aggtctatct tctagtgagg tgctaggtgg tcatattggg aaagaatcca gtcaagagat
    28981 tggtgagctg atagtggaga ctatcttgga tattctaggt agtagaggta tccatttagc
    29041 agttcaaggt tgtgagcatg tcaatcgggc tctcgttgtt gaacgtcagg tggcagagca
    29101 gtttggtctg gaaattgtca gtgtccatcc tactcttcat gcaggaggtt cggggcagtt
    29161 ggcagccttt aagtttatgc aggatccagt tgaggttgaa tttatcaagg ctcatgctgg
    29221 attggatatc ggagacactg caattggcat gcatgtcaag catgttcagg ttccgattcg
    29281 ccctattttg agagagattg gtcatgccca tgtaacggca ctggctagtc gtccaaaatt
    29341 aatcggaggt gcgcgtgcgc actatccgca agatgctatt agaaagacct gagaatgaat
    29401 aaaggagata aaagtgttta aaaaagaccg tttttcaatt cgtaagatta agggagttgt
    29461 aggctctgta tttcttggaa gccttttgat ggctccttct gtagtggacg cagccaccta
    29521 tcactatgta aataaagaga ttatttcaca agaagctaaa gatttaattc agacaggaaa
    29581 gcctgacagg aatgaagttg tatatggttt ggtgtatcaa aaagatcagt tgcctcaaac
    29641 agggacagaa gcatctgttt tgacagcttt tggttatcta tcaggtgaca tcctcaaaac
    29701 gcttggcttg gacactgttt tagaagaaac ctcagcaaaa cctggagagg tgactgtagt
    29761 cgaagttgag actcctcaat caacaacaaa tcaggagcaa gctaggacag aaaaccaagt
    29821 agtagagaca gaggaagctc taaaagaaga agcacctaaa acagaagaaa gtccaaagga
    29881 agaaccaaaa tcggagataa aacctactga cgacaccctt cctaaagtag aagaggggaa
    29941 agaagattca gcagaaccag ctccagttga agaagtaggt ggagaagttg agtcaaaacc
    30001 agaggaaaaa gtagcagtta agccagaaag tcaaccatca gacaaaccaa cagaggaacc
    30061 aaaagttgaa caagtaggtg aaccagtcga gccaagtgaa gacgaacagg caccaacggc
    30121 accagttgag ccagaaaagc aaccagaagc tcctgaagaa gagaaggctg tagaggaaac
    30181 accgaaacca gaagataaaa taaagggtat tggtactaaa gaaccagttg ataaaagtga
    30241 gttaaataat caaattgata aagctagttc agtttctcct actgattatt ctacagcaag
    30301 ttacaatgat cttggacctg ttttagaaac tgcaaaaggt gtctatgctt cagagcctgt
    30361 aaaacagcct gaggtaaata gtgagacaaa taaacttaaa acggctattg acgctctaaa
    30421 cgttgataaa actgaattaa acaatacgat tgcagatgca aaaacaaagg taaaagaaca
    30481 ttacagtgat agaagttggc aaaacctcca aactggggtt acagaagctg aaaaagttgc
    30541 agctaataca gatgctaaac aaagtgaagt aaattctgag actgcaagtc ttaaaacagc
    30601 aatttctaga ttaaatacag ataaagttga actcgaaaat caacttaaga ttgcacaggg
    30661 aaaaactgaa actgatttca gcatggaatc ttggactgtt ttgagtacag ctaaaaataa
    30721 agctcaggaa gtaaaagata acggaacagc gacccaagaa caaataaacg aagcagagaa
    30781 aagtttgaaa acagcccttg ctgacttatc tgttgacaaa acagctttgg gaagcgctat
    30841 cgatacagct actaagaaaa ataaagagaa ttatacaaat caaacatggg cagagttgga
    30901 aacagcgctt acagcagcaa aatctgtaaa tactaacgag tctaaacaaa gcgacgttaa
    30961 cgaagctgct gaaaaattaa ctgcaactat ggaaaaattg gttgaattgt ctgaaaagcc
    31021 acgtttgact ctatctattg aaaagagaga catagatcga aaagctacgg tcacgtatac
    31081 tttggaaaat ccagcaaata ctcaaataaa atcaataact gcaactctga aaaaaggaga
    31141 ggaagttgtt aaggattttg ttttaacaga agaaaatctt aaaactaatc atttaactgc
    31201 tttgtttgaa aagctagact actacaaaga atacactcta tctacggata tggtatataa
    31261 cagaggaaat gatgatgaga cggagagtat ttcagaagaa ctaattcagc tgaatcttaa
    31321 gaaactagaa ttgaaagata tccagacagt ctctctgatg aaatttgaaa atggtcaaga
    31381 aagtcaggtt acacacttgt ctgataaacc gaccgatttg agtaaattat acttaaaagt
    31441 tacatcatca acgtctaagg atgctgtgtt agccgttagc tctatagaag aagagattat
    31501 tgaaaataaa aaaatcttta aaattcatgc agatacacca gaattagtag ttcgtaagaa
    31561 agatggcagt ctttctaagg gatttgacta ttacatggag agagttatcc ctcatgatgg
    31621 tgatatttat tatgatttta aagacttgat ttcagctatg acatctaatc ctacaggtac
    31681 gtttatttta gggagagata tttcctcgcg taatgtaaaa ccggatggaa atggaaaatc
    31741 ttatatcaaa ggtgaattta aaggaaaact acttggtaca aatgataatg ttagacactc
    31801 gatctttgac ttagaatatc cattgtttga tactataaaa tcaggagtcg tgaaagatat
    31861 tgatttcaag catgtcaata tggtattccc agatagcaat caaggagata acgtagcaac
    31921 aattgcaaga gtaatcaaag ataagacaaa aattgagaat gttaatgttg aaggttatct
    31981 cgagggtcga gatcatgtag ctggtttagt taataatctt gaaggtaatt ccgaaattga
    32041 aaatgtatcc tttacaggaa agattaagtc taaaggtggt aattctatta cagcaggtat
    32101 tgcaggtaga aatatcttat ctcgtgttaa acgtgcctat gtaaatgcag atatagaggt
    32161 acatcgatca tctaattcta gcatgcttgt tgcagtaaat ggaataaacg cagatgcaag
    32221 tggtggttgg ggaacctggg gtagacttac tgagtcagtt gctaaaggaa cattagaaac
    32281 caagcaagga gggcaagctg gaggagcctc ttctacagtc tggccttatg gagcaattga
    32341 taatgttgtc agctatgcaa aagtgaccaa agggaaagaa ttatttggat cagatggtga
    32401 tttaaattat gattggttta tgaaaaaaat tagtaatatt tttggtgttc aaggcatcag
    32461 ctcaggcgat tcgggtagtg attctaaatt tacgcgtatt tctgaggaag aagcaaatca
    32521 aaaagttgct tcttataata ttacagctcc caacttgatg agtgactcaa gtcttttggt
    32581 agacagactc aatgaaagtt ggaaaaatac tgatcaattt gaaagtatac aggattatca
    32641 agcccaaaac caattaattt accagaactt gactaaattt actccttatt acaataaaga
    32701 atttattgtt catgaaggaa atgctctcac tcctgaacag gaaatattga agactaagaa
    32761 aatcaaatcg attgtagggt tgaaaggaac agagttcgtt gtagatggca gtgatattga
    32821 tactatcatg cttcattttg aggatggtag tcagaagcga tataaggtaa cctctactgg
    32881 taagttttcg ataactaatt taccggaata tcaggttgaa gatttaaatg tggtgtatac
    32941 atcagaacat atagtacatc cactagattc gtcactgata aataaccttg ttgaagaatt
    33001 gaaaaaagta gaattgtata cagagtctac ttaccaagtt ctaggtattg ataaagataa
    33061 tgctaacaaa ttgaatagaa ctaagagatt attcttagat gagtcattag atgctgttaa
    33121 aacacaattg cctacctttg taaaaacaat gtttgaaaat gagtggttgc acatcaatgg
    33181 agaatctagt ggagctgtcg ctgctttacg acaaaaaatc atggataata agacggctat
    33241 attgcttgct ttgacttata tcaatcgtta ttatgatgtt aaattctcag actataatat
    33301 taaaaaactg atgctcttta aaccaacttt ccatggtgaa aagattgatc tattagatcg
    33361 attaatccga ctaggatcat ctggagaaaa tagattaaaa ggttcagaaa atgcagaaac
    33421 gttcaagcag ttatttgcta gcgaaacgaa gcagaaggat ttggtgactt atttagacta
    33481 caatcgctct ttgttgacta attatcaaac aacaggggaa tggtttaaag aaacgactaa
    33541 ggattatatt caatttgagg aacgtccatc cttagtagag gagattaaag atgccaaata
    33601 tcgagtttac gataatttaa ccgcaccgta ttatcaagga tatatcctac ctctcttaac
    33661 gttgaagaat actcatttag caattttatc gaactatagt actatgacat ttgtcagccg
    33721 tgaaaaacgc cctaattgga aaaatgaaga ttttgataag tgggtgaaat atgtagcaac
    33781 tgctcataga aaccatgttg atacttggta taagatttta cctgataata tcaaaggtaa
    33841 aatggttaaa gagaatgtta ctgctgtttg ggaaggattg agcatcccag gaagtgaatg
    33901 ggtagaccag aatgctgtag atagaaaagg aagagattac gccccagctc gagaattctt
    33961 taatcttgta ggtggtccta tgggaggttg gtatgcttac catggttatg gtgcgcatgc
    34021 tggaggaaga aatcgggtta attatgaggt gtttgatgta ttaagtgagt atggtatatc
    34081 ggtctttact catgaattga ctcacgttaa tgatacttgg atttacttag gagggtatgg
    34141 tagacgtgaa aatatgggac ctgaagctta tgctcaggga ttattccagt ctcctgttcc
    34201 aggtcagccg ggttgggggg cgcttggtct caatatggca tttgaaagaa aaaatgatgg
    34261 tgatctaatt tataatgcct ccccaactca atttgaaaat aggaaagagt tagatagtta
    34321 tatgaaaaat tataacgata ctctcatgat ggtggactac ttggaaggag atgcagttat
    34381 ctctaaaggt aaagaagcta ttactaaatg gtttaaaaaa gttgaaccta aggttgttag
    34441 tcaaacagct cagtatgata cggttcgtca gttgactgct gaagagaaag aaaaactttc
    34501 tgtttctagt gttgatgatt tagttgatca aggattaatg tcagacagag ctgtaggaaa
    34561 taatacctat aatccagctg attttgaaac aagttatatt gcgatagatt atatgactgg
    34621 tatttatggt ggaggaaaga atagtgtagg ttcaccaggt gccttgatgt ttaaacataa
    34681 tactttccgt atgtggggct actatggttt tgaagaaggt gttctaggat atgcttctaa
    34741 taaatttaag caagcatcta gagatgaagg tcatgctgga cttagtgata actttattat
    34801 ttctaagatt tccaaagggg aatttttaac tatggaagca tttaaaaagg gatattttaa
    34861 gaaagtagta gaagagttaa aaactaaagg tattcgtcct gttactatca atcaaaaaac
    34921 atatagcacc tttgaagaat tgcaagaagg atttaagcag gctgttgaaa gagatttgaa
    34981 gaaaaatcag ttagatgaga gggaaacaag aaacttcaaa ttccaagttt tcagacaact
    35041 tcttcaacaa acagatagct ttaaaacttc tatctttaga taatcgaaat ctctcatctg
    35101 ctttgcggat gagggttttc ttattttatg ctatacttaa agtatgcata gaaaaacagt
    35161 gattgatttt aggactttgg gggagagata tacctttacc cagcctatta aagagttgaa
    35221 aacgagaaat gtagaagaag tggcagattt gctggcacaa gtggaaagct accaagagca
    35281 aggttattat gtggtggggt atgtcagcta cgaggctgca cctgcttttg aggaaaaatt
    35341 agcagttcac aaggatcccc tactgggaga gtacctgctt tattttactg ttcatgatag
    35401 cgtagaaact tcccctattc ctctgactta tgaggatatt gatttgccct caaattggca
    35461 ggaagtaacg tctgcagcag actatgaaaa ggccattgcc caaattcacc atcatttacg
    35521 gcagggagat acctatcagg tcaactacac cgtccaactt aagcaaaagt taaatgccaa
    35581 tccttttgcc atctacaatc gtatggtggt agagcaggag gcgggctaca atgcctatgt
    35641 ggaacatgac gagatggcag tgatttccat gagcccagag ctcttttttg agcaaaatga
    35701 tcgcgagttg acaacacgac caatgaaggg gacgactcag cgtggggtaa ctgaccaaga
    35761 agatcttgaa caggccagtt ggttggaaca ggatcctaaa aatcgctctg aaaatatgat
    35821 gattgtggac ctcttgcgca atgatatgaa ccgtatttct gaagttggga gcgagcacgt
    35881 ggagcgtctg tgtcaggtag agcagtattc aactgtttgg cagatgactt cgaccatcaa
    35941 gagtcagttg cgagaggatg tggaccttgt tgaaatcttc cactcactct ttccttgtgg
    36001 ttccataacg ggtgcaccga aaattgcgac aatggagatt atcaaggact tggagcctca
    36061 accgcgtgga gtctactgtg gaacgattgg tctcttgctt ccaaatggac gacggatttt
    36121 taatgtggcc attcgtacca ttcaacttca caaaggtcaa gccatttatg gagttggcgg
    36181 agggattact tgggatagca cttgggaatc tgaataccgt gaagttcatc aaaaggcagc
    36241 agttctctat cgtaaacaag ctcgcttcca attaattaca actggaaaaa tcagccaaaa
    36301 acaactgatg tttgaagaac aacatctgga aaggctgaga aaagctagtc ggtattttgc
    36361 ttatcctttt gacccagaaa ttttgagaca aaagattgaa gcagagtgtc agacttgtga
    36421 tgctaatcaa gattaccgct tgcgaatttc tctcagcaag tctggagaga tagaattcag
    36481 tcgtcaaatc ttaacacctc ttagtccaag tttttgtcag gccaaacttt gtctgcaaga
    36541 agcgaatttg aatcaatcct ttacctattt taaaacgact tacagaccgc atttgagcat
    36601 agaggaacaa gagaagattt accataatgg aaaaggagaa cttcttgaaa cctctatcgg
    36661 aaatttggtt ctgaaaatcg atgggaaact ctacacaccg cctatccgac ttggaatctt
    36721 gccaggaatt tatcaccagt atttactaga aacaggacag gtagaagaga aagtcttgac
    36781 cttggcagat tttgcccaag cagaagctat ttacggctgt aatgcagtga gaggcttgta
    36841 tgagttgcaa gtgataggat tgtgagtttt agctattaat agtttttaat atatattaaa
    36901 atatattggt gtttactttt gatgagatat catatttgtg ttataatgta accgtaaaca
    36961 atagaaattt aaaggagatt tttgatgaaa tcaaaaatag ttttgggagc ttcgctagcg
    37021 atcgcaacac ttagcttagt atctcttgtc gagattgaag gactctcacc gtttttaata
    37081 gagaatgtta gcgcaaatac tcattctgca aataaagtta ttaatcataa agtaagtatt
    37141 tacttagaaa atgctgatga aggtaaaggt ctaactgtaa acttttcaac agacagtgtt
    37201 agtccaaatt tatttgatga gttcgaaaaa aagagtggaa ttacaataac tactatgtta
    37261 gtgaatgcta agacaggtga agttgtagaa aaaagattaa caccaagcgt ttttttacgt
    37321 tccaatgatt taaccagtgg gaccatatct tcgtttattt ttagtgaata tcctgatgga
    37381 gaatataaat atgttgtgtc taaaggagac tttatcgatc ctaagactca gtttaaacat
    37441 cagtatagag gagaatctcc agtttttaga atacgtaatc gaaaatatgt ggagttggga
    37501 acaactgata aaaaattaga tgaaagacgt gataatagcg tttataaaga tggggttgtt
    37561 gaacacaagg taaatttaag tttaacaagt tatcaaggag gtaatggagt tactgcaatt
    37621 ttttcaactg atagtgttaa ctctaactta cttaattctt ttggtgaaaa ggctaaaaaa
    37681 gttttgatta ggtctaagtt aattaatgtt aagactggcg aggttattga tgaaacgttt
    37741 tctccaaaag taagtttaac ctctaaaatt ttgaaaagtg gttctacagc agtattttat
    37801 tttatagatt taactgatgg cgaatataaa tatgttgcgt atgaaagcca gcaatatact
    37861 gatcctcaaa caacattgac tcatcagtat agaggagaat ctcctatttt tagtatcaaa
    37921 gatggaaaat tttctggttt agtatctgcc tcaaaaccag acgaaaaccc gaagccaacg
    37981 ccaaaaccgg atgagaaacc aaaaccttca gcaccacaac aggagaaaac aaaacctaca
    38041 gttcagtctg gttgggtagg ttcatcttat tatcaaaatg gtaaaaaagt cactagtaag
    38101 tggatttttg ataaaaaata taattcatac ttctatctag atgcatcagg aaattatgtt
    38161 caaaacgctt gggtaggtaa ctattatctc aaatcaggcg gatacatggc taaaagtgag
    38221 tggatttatg ataagaacta tggttcatac tactatctaa catcagaagg cagctacgct
    38281 cgtaacactt ggtcaggcaa ttattatttg aagtcaaatg gtaagatggc taaaagtgag
    38341 tgggtatacg atagtaacta caaatcatat tactacttga catcagaagg aagttatgct
    38401 cgtaacactt gggtaggcaa ttactatctt aaatcaaacg gtaaaatggc tgttaatgaa
    38461 cgtacaccag atggttatcg tgtagatggt tcaggtaaat gggttaaata agaaactaaa
    38521 aaataggata ataggtaata tcagatgaat aaaaaaaatt attttcatgt gctttagcat
    38581 tttcaacgat tggaacattg tcaacgattg ataaatcagg agttcttcct ttttcagcgc
    38641 aaacggtgca ggctgacata caaacgctta ccccaatggc aaaatattat attattcttc
    38701 cgaaggatgc agaaatatat aaaacttgga gaggtactgt caatattccc attattgatg
    38761 ctacaaaaac tactccagaa ttatcttatt tcaaagaaga tcatcgcaac tatatagcta
    38821 atgagaataa gtctggtgcc aattacatag agtggaaggg aacagtagaa gagtttaaag
    38881 aggccattaa gaagttgact gataaaaaat caactactgc aacaccaaaa aaggatgaaa
    38941 agccaacacc aaaaccggat gagaagccaa aaccaacacc tacagttcag tctggttggg
    39001 taggttcatc ctattatcaa gatggtaaaa aagtcattag taagtggatt tttgataaaa
    39061 aatataattc atacttctat ctagatgcat caggaaatta tgttcaaaac gcttgggtag
    39121 gtaactatta tcttaaatca ggcggataca tggctaaagg tgaatgggtt tatgatgcca
    39181 cctatcaagc ttggtattat ttgacatcag atggttctta tgcttacagt acatggcaag
    39241 gaaattacta tctaaaatcg gatggtaaaa tggctgtcaa tgaatgggtt gatggtggac
    39301 gttattatgt tggcgctgac ggagtttgga aggaaggtca agcaagtaca gcttcttcta
    39361 gtaatgatag caatagtgaa tattctgctg ctttaggaaa ggcaaaaagt tataattcgt
    39421 tattccacat gtcaaaaaaa aacgtatgta tagacaatta acttctgatt ttgataaatt
    39481 ttcaaatgat gcagctcaat atgccattga tcattagatg attaacagat actggtaggc
    39541 gaaaaaattc cttataattc atttacgcaa acctttgcat aagtgaatgg attttgatat
    39601 actagtactg taagcatttt caattactac acaatgaaaa aggagaatat gatgagtcaa
    39661 aagattattg ggattgacct tggtggaact tctatcaaat ttgcaatctt aacaacagca
    39721 ggagaaatcc aaggaaaatg gtcaatcaag accaacattt tggatgaggg aagtcatatc
    39781 gttgatgata tgattgagtc tattcaacat cgtttggact tgcttggatt ggcagcagcg
    39841 gacttccaag gcattggaat gggatcacca ggtgtggttg accgtgacaa agggactgtt
    39901 atcggtgcct acaacttgaa ctggaaaacc cttcaaccaa tcaaacaaaa gattgaaaaa
    39961 gctttgggca ttccattttt catcgataat gatgccaacg tagcagctct tggtgagcgc
    40021 tggatgggtg ctggagataa ccaaccagac gttgtcttta tgacactcgg tactggtgtt
    40081 ggtggcggta tcgtcgcaga aggcaaattg cttcacggtg ttgctggtgc agcaggtgag
    40141 cttggtcaca tcactgttga ctttgaccag ccaatctcat gtacttgcgg taagaaaggc
    40201 tgccttgaga cagttgcttc agcaacaggg attgtcaact tgactcgtcg ctatgccgat
    40261 gaatacgaag gcgatgcagc cttgaaacgc ttgattgata atggagaaga agtaactgct
    40321 aagactgtct ttgatctcgc aaaagaagga gacgaccttg ctttgattgt ttaccgtaac
    40381 ttctcacgtt acttgggaat cgcttgtgct aacattggtt caatcctaaa cccatcaaca
    40441 atcgtcatcg gtggtggtgt gtcagctgcg ggagaattcc ttctacaagg tgttcaaaaa
    40501 gtttacgatg aaaatagttt cccacaagta cgcacatcta ctaaattagc tcttgcaact
    40561 ctaggaaatg acgctggagt tatcggagca gcatcacttg tattgcaata agataatgag
    40621 agaggaaaat gctaacctag agttagtaat gttcctcttt tattttttat gctatactag
    40681 ttaggacaat gaatgaggtg agagtaaatg acaaaagcag atacgatttt taaagagaat
    40741 attgaatgca ttctaaagga aggtgttttc tcagagcaag ctcgtcctaa gtacaaggat
    40801 gggactgttg ctaattccaa gtatgtaact ggtgcctttt ccgagtacga cttatctaaa
    40861 ggagaatttc ctatcacaac cttgcgtccc attgcaatca aatccgccat caaagaagtt
    40921 ctctggattt accaagacca gtcaaatagc ttagaagtgc ttaatgacaa gtacaatgtt
    40981 cactactgga atgactggga agttggagac acgggaacca ttggtgagcg ctatggtgcc
    41041 gttgttaaga aacacgacat tatcaataag cttctcaaac agttggaaac caatccttgg
    41101 aatcgccgca atattatttc gctctgggat taccaagctt tcgaagaaac agatgggctg
    41161 ctcccgtgcg cctttcagac catgtttgat gtccggcgtg ttgatgggga aatctatctg
    41221 gatgcgacct tgacccagcg ctccaatgat atgctggtgg cccaccacat caacgctatg
    41281 cagtatgtgg ctttacagat gatgattgcc aaacattttg gttggaaggt tgggaagttc
    41341 ttctatttca tcaacaacct ccatatctat gataatcaat ttgaacaagc tcaggaattg
    41401 ctccgtcggg agccgtcaaa ctgccaacca cgcttggttt taaatgttcc tgatgggact
    41461 aatttctttg atatcaaagc agaagatttt gagttggtgg attatgaccc tgttaagcca
    41521 cagttgaagt ttgacctagc tatttaaaag aatagaaaaa agaagttgag aataatccca
    41581 acttcttttg tttcttaacg tgatacgcgg cgacgagctg cttttttacg attttcttcg
    41641 atgaaagctg ctttttgctc ttctggttcg attactttct ttttaaatgc gtatactgca
    41701 cctgcaacgg cagcgacagt tcctgcgaca cctgttacaa gacctttagc gaatccttta
    41761 gccatgagtc ttcctccttt atattctcaa tcagccagcc tcctcaagag gtcacatttt
    41821 tctgactgac ctttttgtgt tataataata gtaacgaaaa aatgggaatt tttcaaggaa
    41881 aaaagatgaa aacaaaaata attgtgattg ttggaccgac tgctgttgga aagacggctc
    41941 tagctattga agttgcaaag cgctttaatg gcgaagtggt tagtggagat agccagcaag
    42001 tctatcgagg acttgatatt gggacggcca aggctagtcc agaagagcag gcagctgttc
    42061 ctcatcattt aatcgatgtt agagagataa ccgagtctta ctcggctttt gattttgttt
    42121 cagaagctaa gatgactatt gaggatattc agagccgtgg caagctagcc attatcgccg
    42181 gtgggactgg actttatatc cagagcttgc tagaaggtta ccacctaggt ggggagactc
    42241 ctcatgagga gattttagct tatcgagcta gtttggagcc atattcagat gaggaattag
    42301 cccatttggt ggagcaagca ggccttgaga ttccccagtt taatcgtcgt cgtgctatgc
    42361 gtgccttaga aattgcccat tttggtcagg atttggaaaa tcaagagatc ttgtatgaac
    42421 cgctgattat ctgcttggat gatgaacgta gtcaacttta tgagcgtatc aaccaccgag
    42481 tggatttgat gtttgaggct gggcttttgg atgaggccaa gtggctgttt gaccattccc
    42541 ctaatgtaca ggctgctaaa ggaattggct ataaggaact ctttccttat ttccgtggag
    42601 agcagacctt tgaggaagct cgtgagagtc ttaaacaggc gacccgtcgt tttgccaagc
    42661 gtcagctgac ctggttccgt aatcgcatgc aggtcacctt ttatcagatt ggagaatctg
    42721 gtgtacaaga ccgcatttta agccagatag aggagttttt agatgattga aacggagaaa
    42781 aaagaggagc gagtcctgct gattggtgtg gaattgcagg gtatggacag ttttgacctc
    42841 tccatggaag aattggctag tttagcgaaa acggcagggg cagtcgttgt agatagctac
    42901 agacaaaaac gtgaaaaata tgattccaag accttcgtcg gctctggtaa gttggaagag
    42961 attgcgctta tggtggatgc agaagaaatc actactgtca tcgtcaacaa tcgtctgacc
    43021 ccaaggcaga atgtcaatct agaggaagtt ctcggtgtta aggtcattga ccgtatgcag
    43081 ttgattttgg atatctttgc catgcgggct cgaagccatg aagggaagct ccaagtccac
    43141 ctagcccaac tcaaatacct cttgcctcgc ttggttggtc aggggattat gctcagccgt
    43201 caggcagggg gaattggttc ccgtggtcct ggtgaaagcc aactggagct gaaccgtcgt
    43261 agcgttcgca atcaaatcac ggatatcgag cgccagctta aggtggttga gaaaaatcgt
    43321 gcgactgtca gagaaaaacg tttggagtct agcactttta agattggttt gattggttat
    43381 actaatgctg ggaaatcaac tatcatgaac atcttgacca gtaagaccca gtatgaagca
    43441 gatgagctct ttgcgactct ggatgcgaca accaagagta ttcatctggg aggcaatctc
    43501 caagtaactt tgacagatac cgttggcttt atccaagatt tgccgacaga gttggtgtcc
    43561 agtttcaagt caaccttgga agaaagcaag catgtggacc ttctggttca tgttatcgat
    43621 gctagcaatc cttaccacga ggagcatgaa aaaacggttc tctccatcat gaaagacctg
    43681 gacatggaag atattcctca cttgacgctt tataataaag cggatttggt ggaggatttc
    43741 acgcctaccc aaacgccata taccctcatt tctgccaagt ctgaggacag tcgtgaaaac
    43801 ttgcaagcat tattgctaga taagattaag gaaatttttg aagcatttac cctgcgagtg
    43861 cctttttcaa agtcctacaa gattcatgat ttagagagtg ttgcaattct ggaagaacgt
    43921 gattatcagg aagacggcga agtgattaca ggctacattt ccgagaaaaa taaatggagg
    43981 ttagaagaat tttatgactg atattaaaac tttggctcta aagtatggag gttatacaag
    44041 tctggacaag gtctatctgg atcagcttct agctggtaaa acagatcagg agcagttaac
    44101 acttattaca cctccgccaa gtgttgttaa tgcctacttt gcagaactct atcagaaaaa
    44161 gagtcctcag gctgcgacgg attattttgc agaactcagt caggaactga atctttacaa
    44221 tactgagcca agtttcaccc tagaaaataa gccttttatt cggcttaatc tgtctggtaa
    44281 atcctttggt ttttgttatg agagtgacgg ccttggtcgg attttctttg aaaatgagga
    44341 gaaaatctcg gatgacttgc tctttgaaat tgcgcaaatt ttcccccatc aattagtctt
    44401 tgaagagtct ggtaagattt acatgaagcc tgtcgaggac gaggaagtta tcagcctaga
    44461 aagtctcaca gctttgactg atttggaaag attggctgat ggtcgaaaac gtctcaaagg
    44521 ctacagccaa gaggatttat tgcaagaagc tgctgctttt tctggcaaac gctatttccg
    44581 atcggaaaac cgcacagcca tgttatatat tgattaatta gaaagtatcg aatggatatt
    44641 caatttttag gaacgggggc tggtcagccc tctaaagccc gcaacgtttc aagtctcgcc
    44701 ctgaaacttt tggatgagat taacgaagtt tggctctttg actgtggaga aggtacgcaa
    44761 aatcgcattc tggaaaccac aattcgacca cgtaaggtca gcaaaatctt tattacccat
    44821 ctgcatggag accacatttt tggtttgcca ggtttccttt ctagccgtgc ctttcaggcc
    44881 aatgaagagc agacagattt ggaaatctac ggacctcaag gaatcaagtc atttgtctta
    44941 accagccttc gtgtgtcagg ttctcgtctg ccctaccgca ttcatttcca tgagtttgac
    45001 caagattctc tgggtaaaat tcttgaaacc gataaattca ctgtgtatgc agaggagctg
    45061 gaccacacta ttttctgtgt tggctatcgt gtcatgcaaa aggatctaga agggacgctg
    45121 gatgctgaaa aactcaaggc tgctggtgtt ccgttcggcc cgctttttgg taaaatcaaa
    45181 aacggccagg atcttgtttt ggaagacgga actgaaatca aggcagcaga ctatatctca
    45241 gcgccacgtc caggtaagat tatcactatt ttaggagaca ctcgaaaaac gggtgccagt
    45301 gtgcgtctgg ctgtcaatgc agatgtccta gttcatgagt ccacttatgg caagggtgat
    45361 gaaaaaattg ctcgtaacca tggtcactca actaatatgc aagctgcaca agtagcggta
    45421 gaagcaggtg ccaaacgcct cctactcaac catatcagtg cccgtttcct ctcaaaagat
    45481 attagcaaac tcaagaaaga cgctgccaca atttttgaaa atgtccatgt ggtcaaagac
    45541 ttggaagaag tggaaatcta gcagtcacag aaaggataag tatgcctact attctcatta
    45601 ccggagctag cggtggtcta gctcaagaaa tggtcaaact cctgcccaat gaccaactca
    45661 tcttgcttgg tagaaataag gaaaaattag cccaactcta cggaaattat tcccatgcag
    45721 aattgattga aattgatatt accgacgatt cagccctaga agctctggta actgatcttt
    45781 atctccgcta tggcaagatt gatgtcttga ttaacaacgc tggttacggg atttttgagg
    45841 gatttgacca gattgctgat aaagatattc accagatgtt tgaggtcaat acctttgccc
    45901 tgatgaatct gtctcgtcac cttgcggctc gtatgaagga aagcagcaaa gggcatatca
    45961 tcaacatcgt cagcatggca ggtctaatag ctactggcaa gtctagtctt tactcagcga
    46021 ccaagtttgc ggctattggt ttttcaaatg ctctgcgact cgaacttatg ccctatggag
    46081 tctatgtgac aacagtcaat ccaggtccaa tccgaacagg atttttcgac caagccgacc
    46141 cagatggaac ttatcttaaa tcggttgacc gcttcctgct agaaccagat gcagtggcta
    46201 aaaagattgt caagattata ggaaaaaaca aacgagaact caatctcccg attttgttga
    46261 acctagctca taagttttat accctctttc ctaagctagc tgataagttg gcaggggaaa
    46321 cttttaatta taagtaaaaa gaaccaatgt gcaggttgtt gctagcctac atattggttc
    46381 ttatcatttc tcaactatca aactgaactt cttctaggag atagtctata aagcgttcgc
    46441 ccatcttaga taggctggtt ttctcatgct ggatatagac cagctcgatc gggtcatcaa
    46501 tatccagtgg gatagaaacg atattgtctc cgtttaggtt gctgttcaaa atccctgtcg
    46561 caatggtata accatccaaa ccaatcaaga gattaaagag ggtggcacgg tcactgacca
    46621 caatggattt cttgtggtgt tcttgagaaa gaatctcttc tgaaaagtag aaggagttgt
    46681 gcgtcccttg gtcatagctg aggtaaggga aattctccaa atcagacagt ttcaccttgt
    46741 ctttctttgc cagagggttg gtcttgctga caaagatatg tggttgcgct gtgaagagat
    46801 ggtgggctag caggtgattg tcatccagca tcttggttaa aacatcacgg ttgtaactgt
    46861 ttaagaagag gaccccgacc tcactgcgga agttcttgac gtcgtcgata atctcccaag
    46921 tccgagtttc acgaaggaag agttcgtatt tctccatatc gcttttcttg agcaaagaga
    46981 caaaggcatt gaccacaaag gcatagtgtt gagacgaaac gctaaatagt tcgcggtggg
    47041 cgacaggatt tttatagcgt tcctccagaa gctgggtctg ctcgacaacc tgacgggcat
    47101 aagagagaaa ctccatccca tcacgggtca aggtgattcc cttgggattg cggataaaga
    47161 tctcaatgcc catttcattt tccaaatctc gcactgcatt ggagagactt ggctgagtga
    47221 taaagagttg cttggctgcc tcattcatgg agccagtttc gacgattttg ataatataat
    47281 gtaattgttg aattctcatg tttttattgt accatacttg ccttagaatc gctaaagaag
    47341 ataggaaaat aaggagcatt gtgtgagtct cttcttgaaa aaaacacaaa attttgctag
    47401 aatgagtctt atgaaaacat tctatgatgt gcagcaattc ctcaaacgat ttggtattat
    47461 tgtttacatg ggaaaacgct tatatgatat tgaactgatg aagttggaac tatctcggat
    47521 ttacgatgca gggttgatgg ataaattaga ctatctagag gcagaagcag ttcttcgcag
    47581 agagcacaag gtagaattgg attatattga gaaaaatgga gaaaagaact aatggttact
    47641 tggattttgt gggcacttat actagcaatg ttggcgtgga tgggctttaa ctatcttcgt
    47701 attcgccgtg cggctaaaat tgtggacaat gaggagtttg aagccttgat tcgtacgggt
    47761 caattgattg atttgcgcga cccagcagaa ttccacagaa aacatatcct tggtgcacgc
    47821 aatattcctt caagtcagtt gaaaactagt cttgcagccc ttcgtaaaga taaacctgtc
    47881 cttctctacg agaaccaacg tgcgcaacga gttacaaatg cagctcttta cttgaaaaaa
    47941 caaggttttt ctgagattta tatcctttct tatggcttgg attcttggaa agggaaagtg
    48001 aagactagct aaccttattt ccaaattagt cgaatgatag gatgaagcta ttgttttata
    48061 gtataattaa tttgtataaa atttaaggag ttcttagaac ataaaagaaa agaagaaaaa
    48121 tccacttttt gtgggtatct tgtcgattat tcttggtttg ttatttccaa ttgtaggcct
    48181 gattttgggt atcataggat tggtcttggc tatttcatac caaaaagagt cataattaga
    48241 ctataaaata gaaaagattc ttaatatctt aggaattgtg atttctgtag ttaactggat
    48301 tgtagcaatc gccttaattt ttcggtaaat aaaagaaaaa agctttagtt ttaaagcttt
    48361 ttttgtttta tcgactcatc tctaaatagt ttttaatgat ttgtaactct ttttggttca
    48421 aagggcggta gttactttct gctaaatctg ggttcaatgt gaagtcccca aattggattc
    48481 tcttgaggat agtcacctta acaccaaccg agaggaacat tttcttgatt tgatgaaatt
    48541 ttccttctga aatggtgata gaggcttgac tgatggaggg acttgcagat agaatctcta
    48601 gttttgcggg tttacagaca gtaccatcta aaaagacaat tcccttttga aaggcttgga
    48661 tatggtcagg tgttagaagt ccattaacct caacttgata agtcttatcg acatgatatt
    48721 ggggatggag gagttggaag cccaagggac cgttatcggt caagaggagg agtcccgttg
    48781 tatctcggtc cagtcggcca acggcataga gcttgtcaga ctggatgtca gatggaagca
    48841 ggtccatgac ggtcggaagt tccttgtctt tgttggctgt aacgacacca gcaggtttat
    48901 gaagcataag ataggtgtgt tcatagcctt gaatgattcg atcctgaaaa aggagttctt
    48961 gtagtcctgt atcgatattt tgagctaggg agcgggctgg gcaaccatcg actagaattt
    49021 tccctctgag gagtgcttgc ttcatggcct ttcggctgat tttttcttgg gctaataaat
    49081 tatctaaacg catactgtgc ctatcttatc ataagtcgct tgctttgaaa aggcttgacg
    49141 tgaaaagaaa agcggagtga aaacatttac acttgcttga gttatgttat ttatttgaaa
    49201 ttatggtata atcgttcagt tagaaaataa attttgaata ttatagagga aatcatgaca
    49261 aaattaagag aagatatccg taacattgcg attatcgccc acgttgacca cggtaaaaca
    49321 accctggttg acgaattatt gaaacaatca gaaacgcttg atgcacgtac tgaattggca
    49381 gagcgtgcta tggactcaaa cgatatcgaa aaagagcgtg gaatcaccat ccttgctaaa
    49441 aatactgccg ttgcttacaa cggaactcgt atcaacatta tggacacacc aggacacgcg
    49501 gacttcggtg gagaagttga gcgtatcatg aaaatggttg acggtgttgt cttggtcgta
    49561 gatgcctatg aaggaaccat gccacaaact cgtttcgtat tgaaaaaagc cttggaacaa
    49621 gaccttgtcc caatcgtggt tgttaacaaa atcgataagc catcagctcg tccagcagaa
    49681 gtagtggatg aagtcttgga acttttcatc gagcttggtg cagatgacga ccagcttgat
    49741 ttcccagtgg tttatgcttc agcgatcaac ggaacttctt cattgtcaga tgatccagct
    49801 gaccaagaag cgactatggc accaatcttt gacacgatta tcgaccatat cccagctcca
    49861 gtagataact cagatgagcc tttgcagttc caagtgtcac ttttggacta caatgacttc
    49921 gttggacgta tcggtatcgg tcgtgtcttc cgtggtacag ttaaggttgg ggaccaagtt
    49981 accctttcta aacttgacgg tacaactaaa aacttccgtg ttacaaaact cttcggtttc
    50041 tttggtttgg aacgtcgtga aatccaagaa gccaaagcgg gtgacttgat tgccgtttca
    50101 ggtatggaag acatctttgt cggtgaaacc atcactccga cagatgcagt agaagctctt
    50161 ccaatcctac acatcgatga gccaactctt caaatgactt tcttggtcaa caactcacca
    50221 tttgctggta aagaaggtaa atgggtaact tctcgtaagg tggaagaacg cttgcaggcg
    50281 gaattgcaaa cagacgtttc ccttcgtgtt gacccaactg attcaccaga taaatggact
    50341 gtttcaggac gtggagaatt gcacttgtca atccttatcg aaacaatgcg tcgtgagggc
    50401 tatgaacttc aagtatctcg tccagaagtt atcgtaaaag aaatcgacgg tgttaaatgt
    50461 gaaccatttg aacgtgtaca aatcgacact ccagaagaat accaagggtc tgttatccaa
    50521 agcctttctg aacgtaaagg tgaaatgttg gatatgattt caactggtaa tggtcaaact
    50581 cgtttggtct tccttgttcc agcgcgtggt ttgattggat actcaactga gttcttgtca
    50641 atgactcgtg gttacggtat catgaaccat accttcgacc aatacttgcc attgattcca
    50701 ggggaaattg gtggacgtca ccgtggtgcc cttgtttcta tcgatgctgg taaggctaca
    50761 acttactcaa tcatgtctat cgaagaacgt ggtacgatct ttgtcaaccc aggtactgag
    50821 gtttatgaag gaatgatcat cggtgaaaac tctcgtgaaa atgacttgac agttaacatc
    50881 acgaaggcaa aacaaatgac caacgttcgt tcagctacta aggaccaaac agctgttatc
    50941 aagacgcctc gtatcttgac acttgaagag tctcttgagt tcttgaacga cgatgagtac
    51001 atggaagtaa cgcctgagtc tatccgtttg cgtaaacaaa tccttaacaa agcagagcgt
    51061 gagaaagcta acaagaagaa aaaatcagct gaataagagc tagaaagaga gaaagatggt
    51121 ctatttagtc ctaggaattt tactgctcct actctatgta tttgcgacac cagaaagcat
    51181 taaagggaca gtcaatatcg tcgctatggt atgtatttta gtggcactct tgattttatt
    51241 ggttctatct tttctgaaaa tttttcaatt accaacagaa atattcctag caatagccat
    51301 gttgctccta gcttacttta gtgttagaga cattacactc atgccagtca aaaaaagtaa
    51361 aagaagataa aaaagagagt tttggctctc ttttttgcta ggaattttac aagattgcaa
    51421 tttatttttg agttatcacc atctcttttg tttggataat atgaatggga aaaacttgaa
    51481 taaaattcgt taatggaatc tattttatat ttggttagta ctggttgcat attattttga
    51541 aataa
//
LOCUS       DAVLBE010000010        47631 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.010, whole genome shotgun sequence.
ACCESSION   DAVLBE010000010 DAVLBE010000000
VERSION     DAVLBE010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 47631)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47631)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47631
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.010"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(381..1361)
                     /locus_tag="VXB91_000597"
     CDS             complement(381..1361)
                     /locus_tag="VXB91_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HEV0470096.1"
                     /translation="MKNPALLEEIKTYRGRDEVPEDFDAFWDGEVKNVSTLPSYHLEE
                     RDFHIPQVKCYELTFEGSKEGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAMEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFHDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHEAMNVFVNDQVYNWLCGSEIPFKYLK"
     gene            complement(1678..3693)
                     /gene="recG"
                     /locus_tag="VXB91_000598"
     CDS             complement(1678..3693)
                     /gene="recG"
                     /locus_tag="VXB91_000598"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HEV0470097.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     TKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKDLAEYKQALRRIKFEELFYFQMQ
                     LQMLKSENRVQGSGLVLNWSQEKVTAVKVSLPFALTQAQEKSLQEILTDMKSDHHMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLI
                     GSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLALIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQAYVISPLIEESEALDLKNAIALSEELTTHFAGKAEVALLHGRMKSD
                     EKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIEAWQEDPEWRMIALHLEKKEHLD"
     gene            complement(3712..4815)
                     /locus_tag="VXB91_000599"
     CDS             complement(3712..4815)
                     /locus_tag="VXB91_000599"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEV0470098.1"
                     /translation="MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKLAVVKANAY
                     GHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVCVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLDLPYDLIPALTLESALVHVKTVPAGACMGYGATYQADSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKLYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            complement(4805..5173)
                     /locus_tag="VXB91_000600"
     CDS             complement(4805..5173)
                     /locus_tag="VXB91_000600"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HEV0470099.1"
                     /translation="MRMIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLK
                     GRRQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLS
                     ISHTDQFVTASVILEENHES"
     gene            complement(5212..6243)
                     /locus_tag="VXB91_000601"
     CDS             complement(5212..6243)
                     /locus_tag="VXB91_000601"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEV0470100.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMGLENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEIFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            complement(6245..7276)
                     /locus_tag="VXB91_000602"
     CDS             complement(6245..7276)
                     /locus_tag="VXB91_000602"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEV0470101.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            complement(7357..9870)
                     /gene="secA"
                     /locus_tag="VXB91_000603"
     CDS             complement(7357..9870)
                     /gene="secA"
                     /locus_tag="VXB91_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HEV0470102.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMAALTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYAQRYDVITADRDL
                     APEIQSMIKRTIERVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRSLKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            complement(10016..10303)
                     /locus_tag="VXB91_000604"
     CDS             complement(10016..10303)
                     /locus_tag="VXB91_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0470103.1"
                     /translation="MAHLKSFITRYSKVYIGLVLLIWLSFFFIPWDRAILGVRIDIFI
                     IQKILLAFGILSILMALLSKKVSLFVFGLICCLSLWINLFITFAILPIFGN"
     gene            complement(10331..10963)
                     /locus_tag="VXB91_000605"
     CDS             complement(10331..10963)
                     /locus_tag="VXB91_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0470104.1"
                     /translation="MRLEIINGQKIYGKRPILNQLNLVFQSGKIYGLKGDNGSGKTVL
                     LKVLAGYIKLDKGKVLQDGKVYGIKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDVEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRLTKQVILSYLKKENGLVILTSHISEDISDLCTDVLVVENGHIQM"
     gene            complement(10967..11608)
                     /locus_tag="VXB91_000606"
     CDS             complement(10967..11608)
                     /locus_tag="VXB91_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0470105.1"
                     /translation="MFKNFNNILLKRKIVLLLRIVLMMILINHLLSTAVQKQDAVIFF
                     KRELISIFSYNDYSEANLEIPKLLLNLSLFMVGWLSVILLESDLADHYHHLIRYQSSS
                     FFDYTRKRLVVISKFFTQDLFVWFLGLLPLGIHFKTVALFFLLAQLMMLYLLLSYLIA
                     LISAGAGFSFFLYFLVFVGQEWMMDHIVTVYLLLLSLLVMLIVSRLEEKFKKG"
     gene            complement(11601..12392)
                     /locus_tag="VXB91_000607"
     CDS             complement(11601..12392)
                     /locus_tag="VXB91_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0470106.1"
                     /translation="MKIPLLTLARHKFVYVLLTLLFLALVYRDVLMTYFFFDIHAPDL
                     AKFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIPIIIVLLGFQYIELKNKVLRLSIG
                     REVSYPGLKRKLTLQVASIPCLIYLVTVLTIAIITYFLGTFSPLGWNSLFSDGSGLQR
                     LLDGEIKSYLFFTCVLLIGIFINAIYFLQIVDYVGNVTRSAITYLMFLWLGSMLLYSA
                     LPYYMVPMTSLMQASYGDVSLMKLFTPYILYIVPYMVLEKYEDNV"
     gene            complement(12414..12806)
                     /locus_tag="VXB91_000608"
     CDS             complement(12414..12806)
                     /locus_tag="VXB91_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0470107.1"
                     /translation="MKIKKLLKMVIPVLMISAVGTTFVEANQIGAFSNFVITTSYKRT
                     GYLTKENEGAEYIMNLNPCRNLHPMTVKHRIVNSNGEARSGESLTTCGTRSTHGNWAT
                     VGYVYAADMARQNWWDLSAAISGSWSPN"
     gene            13133..13984
                     /locus_tag="VXB91_000609"
     CDS             13133..13984
                     /locus_tag="VXB91_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0470108.1"
                     /translation="MRWDYGQIFKEIRKSKGLTQQDVCGQVIHRTTLTNIEHGKVIPS
                     FENMVFLLEQIDMSLAEFKYICNEYHPSKRRDIIVESQNPSTFQDTRKMVELTEKCQK
                     YLKTHHDVPIQNIYRHTKIVTELRTKGFKNNHVLKDLYEEIWDYLEPMDTWYISDLKL
                     LGTILFFFPSENLPLLIDRIMKTIEKYKYFRETKAFLSSFLANLSTVYFQHHLFKECE
                     TITLQLLVLAEELKIYDILGFSQVRLGILQHNSDLIDKGITLLRLTKEEALVKILEKE
                     INDFSNL"
     gene            complement(14216..14566)
                     /locus_tag="VXB91_000610"
     CDS             complement(14216..14566)
                     /locus_tag="VXB91_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0470109.1"
                     /translation="MEHLFKMIILLPCFYFFSWIDKDNRESKFFPIFYYFYWIYITLY
                     ALFSLAWTVFSVLFFNIVLRNLTDIKLWGIWLLLLLIAFASDWLAYVFFKKMIRLRRE
                     LGKSKGVHKGRCRN"
     gene            complement(14706..15041)
                     /locus_tag="VXB91_000611"
     CDS             complement(14706..15041)
                     /locus_tag="VXB91_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0470110.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWFYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            complement(15129..16439)
                     /gene="der"
                     /locus_tag="VXB91_000612"
     CDS             complement(15129..16439)
                     /gene="der"
                     /locus_tag="VXB91_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HEV0470111.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            complement(16453..17166)
                     /locus_tag="VXB91_000613"
     CDS             complement(16453..17166)
                     /locus_tag="VXB91_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HEV0470112.1"
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQ
                     SYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMAL
                     GVPNQHHDMKPRLPLENVVFEEEYQEQSTEAIQAYDRVQADYAGARATTSWSQRLAEQ
                     FGQAEPSSTRKNLEQKKLL"
     gene            complement(17163..18059)
                     /gene="dnaI"
                     /locus_tag="VXB91_000614"
     CDS             complement(17163..18059)
                     /gene="dnaI"
                     /locus_tag="VXB91_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HEV0470113.1"
                     /translation="MESVGDVLKRQPSRFYYQDLVQKIMKDPDVAAFIQQESLTPEEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVKNHGYADVSYEETPELIAAEKEAA
                     IKNRLKLINLPASLKKASLAQVDLDDLGRLPVFEKLLAFVEQYPAIRKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAISDGNVKTLVDEIKLSEVLILD
                     DIGAEQSTAWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKVKHGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            complement(18060..19229)
                     /locus_tag="VXB91_000615"
     CDS             complement(18060..19229)
                     /locus_tag="VXB91_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HEV0470114.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLALHAPLSSQD
                     FLEHPVYRRLLEKKIGDSAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLEHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPVSSDFSLKETTIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEKAVLRIRER
                     GQKAKTQKQNQTAPVKTNVPKWSNPEYKNETSEETRLELERKKQELLARLEKGGD"
     gene            complement(19230..19703)
                     /gene="nrdR"
                     /locus_tag="VXB91_000616"
     CDS             complement(19230..19703)
                     /gene="nrdR"
                     /locus_tag="VXB91_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HEV0470115.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            19843..20208
                     /locus_tag="VXB91_000617"
     CDS             19843..20208
                     /locus_tag="VXB91_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV0470116.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMTH
                     FGYEKEELPGVVSDYIKGV"
     gene            20213..20908
                     /locus_tag="VXB91_000618"
     CDS             20213..20908
                     /locus_tag="VXB91_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0470117.1"
                     /translation="MSLLVFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            20925..21692
                     /locus_tag="VXB91_000619"
     CDS             20925..21692
                     /locus_tag="VXB91_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0470118.1"
                     /translation="MFWNLVRYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLGISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAVYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVEELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(22045..23244)
                     /locus_tag="VXB91_000620"
     CDS             complement(22045..23244)
                     /locus_tag="VXB91_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0470119.1"
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHLQGS
                     SMAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLAQTIQFTEKIDEA
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILDHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINGYAEGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(23241..24134)
                     /locus_tag="VXB91_000621"
     CDS             complement(23241..24134)
                     /locus_tag="VXB91_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0470120.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQEIYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
     gene            24251..24331
                     /locus_tag="VXB91_000622"
                     /pseudo
     CDS             24251..24331
                     /locus_tag="VXB91_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            24841..25029
                     /locus_tag="VXB91_000623"
                     /pseudo
     CDS             24841..25029
                     /locus_tag="VXB91_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            25444..26061
                     /locus_tag="VXB91_000624"
     CDS             25444..26061
                     /locus_tag="VXB91_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEV0470121.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(26381..27268)
                     /locus_tag="VXB91_000625"
     CDS             complement(26381..27268)
                     /locus_tag="VXB91_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV0470122.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEVVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGETIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(27417..29300)
                     /locus_tag="VXB91_000626"
     CDS             complement(27417..29300)
                     /locus_tag="VXB91_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEV0470123.1"
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEV
                     IENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQ
                     RAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG
                     LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGS
                     VLPAFIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYI
                     LIATKAILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAA
                     MTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAG
                     AIGGGLASILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYE
                     DEVDATAAAKQAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQG
                     IAVKPSQGVVYAPADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFEAKV
                     AQGDKVKVGDVLGTFDSNKIATAGLDDTTMVIVTNTADYASVAPVATGSVAKGDAVIE
                     VKI"
     gene            29677..31131
                     /locus_tag="VXB91_000627"
     CDS             29677..31131
                     /locus_tag="VXB91_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEV0470124.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLVHFRETGVKVLPDTPLDS
                     HGAYSGSAMQFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFKGQYYAVVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRT
                     AYMMECPNLVFVEEQPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDRFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRTSEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNGQVTVDRSQAGEQYAQEFGITRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGTYYELDYGRKTN"
     gene            31112..32077
                     /locus_tag="VXB91_000628"
     CDS             31112..32077
                     /locus_tag="VXB91_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV0470125.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     GYKPNNLARSLQGKPAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQSIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILVIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(32112..33386)
                     /locus_tag="VXB91_000629"
     CDS             complement(32112..33386)
                     /locus_tag="VXB91_000629"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HEV0470126.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFT
                     AQVHQRQMIGQVALYQVANPKLAQEKIASKKAELLELANQAYPSIVKRGGGARDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMGILSNYATDSL
                     VTASCRIAFRYLSRQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VALSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVERLISDKTFNLETAQRYLENLRS"
     gene            complement(33386..34558)
                     /locus_tag="VXB91_000630"
     CDS             complement(33386..34558)
                     /locus_tag="VXB91_000630"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HEV0470127.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENTDSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTALSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            complement(34689..34937)
                     /locus_tag="VXB91_000631"
     CDS             complement(34689..34937)
                     /locus_tag="VXB91_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0470128.1"
                     /translation="MVSSSGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPISQFY
                     QKFVDEMGRIYSGNLILQELITVNGAYKATYIGELSSN"
     gene            complement(35005..35630)
                     /locus_tag="VXB91_000632"
                     /pseudo
     CDS             complement(35005..35630)
                     /locus_tag="VXB91_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            complement(35692..36141)
                     /locus_tag="VXB91_000633"
     CDS             complement(35692..36141)
                     /locus_tag="VXB91_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEV0470129.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     gene            complement(36143..36901)
                     /locus_tag="VXB91_000634"
     CDS             complement(36143..36901)
                     /locus_tag="VXB91_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEV0470130.1"
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAKPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLMN"
     gene            complement(37016..38995)
                     /gene="pknB"
                     /locus_tag="VXB91_000635"
     CDS             complement(37016..38995)
                     /gene="pknB"
                     /locus_tag="VXB91_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HEV0470131.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIVLTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSVE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            complement(38992..39732)
                     /locus_tag="VXB91_000636"
     CDS             complement(38992..39732)
                     /locus_tag="VXB91_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HEV0470132.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTE
                     TLVRFANNAGGLDNITVALVSMNEEDEE"
     gene            complement(39747..41060)
                     /gene="rsmB"
                     /locus_tag="VXB91_000637"
     CDS             complement(39747..41060)
                     /gene="rsmB"
                     /locus_tag="VXB91_000637"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HEV0470133.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLLAADKG
                     LVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNALLRRILREGWPDIASIKRKNKRDSIAYSLPVWLVAKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANDSLLATTGLVKEQGHFAG
                     HNLFADGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVEDRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            complement(41053..41988)
                     /locus_tag="VXB91_000638"
     CDS             complement(41053..41988)
                     /locus_tag="VXB91_000638"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HEV0470134.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEELMKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGTLFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHAFLKGDRFKIYEALPVEGQGNPGEILSIGKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            complement(42001..44397)
                     /locus_tag="VXB91_000639"
     CDS             complement(42001..44397)
                     /locus_tag="VXB91_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HEV0470135.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVLGLESQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKAMLPGFLNSSYDKILYPLEGLSQEERVRLFGSEDSLAFSSLDLAKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGAVTIVQKEVQRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEVAYK
                     QDSNPRYHARDVAILRAQYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSRSIRYYGTGTQKAYDEL
                     AELFPQARILRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNSQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTHNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            complement(44463..44777)
                     /locus_tag="VXB91_000640"
     CDS             complement(44463..44777)
                     /locus_tag="VXB91_000640"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HEV0470136.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            complement(44802..45428)
                     /gene="gmk"
                     /locus_tag="VXB91_000641"
     CDS             complement(44802..45428)
                     /gene="gmk"
                     /locus_tag="VXB91_000641"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HEV0470137.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            complement(45558..47171)
                     /locus_tag="VXB91_000642"
     CDS             complement(45558..47171)
                     /locus_tag="VXB91_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HEV0470138.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
     gene            complement(47241..47531)
                     /locus_tag="VXB91_000643"
     CDS             complement(47241..47531)
                     /locus_tag="VXB91_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000451507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEV0470139.1"
                     /translation="MEVEEKSIELSYEYVDDGYSGSNFERPNFKNMIDDLNKGKFSII
                     MVKDLSRFGRDYIESGKYLQKIFPEKGIRFISVNDNYDSDNADVSDIHLRFV"
BASE COUNT        13740 a        10761 c         8995 g        14135 t
ORIGIN      
        1 aacatatata cggcaaggcg aagctgacgt ggtttaaaga gatttttgaa aagtattaac
       61 acctacagac aagcctgacg atagcaagaa ctaccctact cgataggtat cggcttttgc
      121 tttctgaaaa aaattatttt aagcaatttg acaaatctag caacaaaaaa ttctataaat
      181 ataatagatt gaaactagaa tagtacacat ttgcttctaa aacattgtta gaaatcgatt
      241 tgactgtcct gatcgttttg tcctattctt gtttcatttt actatatttc catgataaaa
      301 cgcatagtat caagtttttt taatcccctg atactatgcg tgtttgtaat ttttaagatt
      361 ttgtgcttag agtcgactcc ttattttaga tatttaaaag gaatctcact tccacagagc
      421 cagttgtaga cttggtcatt gacaaataca ttcatggctt cgtgagcata ctcaggcatg
      481 atgcgatagg ttttatcgca ggtcagacga ttataaatcg caaactgggt aatgggatag
      541 caaacatcgt cgtccaagcc cgtaatcatc ttaacctcac cttggatacg atgggcaaga
      601 tttttgacat cgatataggc aagggtcgcc atgatttcct cctctgtttc atggaagggg
      661 tcgtgaaact tgaaataacg gaaaagttcg tcgtaagcct cgctagtatt accaatctca
      721 atcacccgtc tgaagtctga caagaaggga taaatggcaa ctgttttctg aattcgagga
      781 ttgagcgctg ctgcaactag agctagagcc cctccttgtg aggcaccata gctagaaaga
      841 cgcttctcat caacctgaga cagactagca acaatttcga ccaactggta aatatccaga
      901 taaacatcct tataaaagag gtggtcccga ccttccatag caccacggat aatatgcccc
      961 ttcacggtat ttcctaaagg agaacgcaag ccgtcttgtg agtaacctga ctggccccgc
     1021 acatccatgg aaacaacacc gtaaccagct acggtgaagc ccagcatgtc ggcccagtcc
     1081 cagccacgtc ccatataacc atgaaaatgg aagattaatg gaaccttctc ctcactcttt
     1141 ggaagaacaa tgcgtgcata gacctttcct tccttgcttc cttcaaatgt taactcatag
     1201 cacttgactt gaggaatgtg gaaatctctt tcctccaagt ggtaggatgg aagtgtggaa
     1261 acatttttca cttccccatc ccagaaagca tcaaagtctt ccggaacctc atcccttcct
     1321 ctataggtct taatttcttc tagcaaagct ggatttttca tagcatgctc cttttatttt
     1381 gtaatcgtta ccacaactgt agcatatcta tgtaatcaat gcaagaaaga agggtaaata
     1441 gaaagtgaat ttagattctt tacttttagg atgatgggct gaaagtagtt ttagaaacga
     1501 aaaaagagca tttcgctctc tcttctgttt atactagttt tttgcttcct tcttttggaa
     1561 agtggtttgg taatttactt taatcgttac tgtcatatga gagtcctcgt ttctttttga
     1621 tgactttagt ataagagcca aacctaaaaa ctagcttaag ttttccttag agaaagctta
     1681 atccagatgt tctttctttt ccagatgaag ggcaatcatg cgccactctg gatcttcttg
     1741 ccaagcttct atagaactaa tgtagctagc aacctttctt gcttcttcta aaatcggaaa
     1801 atcttcgata atatcagcca cttggaactc tggaagtcct gactgtctgg ttccaaaaat
     1861 ctcaccagaa ccacgcattt tcaaatcttc ctccgcaagg acaaatccat tggtcgtttc
     1921 tgtcatgata cgcatgcggt ctttcccaga atccgtcttg ggattagcaa cgagaacagc
     1981 gtaggactgc ttgtcccccc gaccgacacg acctctaagc tggtgaagtt gactgagacc
     2041 gaagcgatcg gcatccatga taatcatgac agtcgcattg ggaacgttga ccccaacctc
     2101 aataaccgtc gtcgaaacca gaatatccgt ctttctctcc ttgaaatcct gcatgatctg
     2161 gtctttttcg tcactcttca tcctaccatg tagaagagcc acctctgcct tgcctgcaaa
     2221 atgagtcgtc aactcctctg ataaggcaat ggcatttttc aaatctagag cttctgattc
     2281 ttcaatcaaa ggagagatga cataggcttg ggaacctttt tgaatttccc cctctaacca
     2341 agtcaagacc tgaggtagtt gctcatgttt gatccagcgc gtcacaatag gcttccgacc
     2401 tgctggcatc tggtcgataa tggaaacatc catatctcca aaggctgtga tggcaagcgt
     2461 ccgtggaatg ggagtcgccg tcatcatgag gacatctgga ttgtcacctt tttcccgtaa
     2521 aatacgcctt tgccctacac caaaacggtg ctgctcatcg ataataatca aagcaagacg
     2581 agcatactcc accccatctt gtatcagagc gtgagttccg ataatcaaat cagcctcacc
     2641 cttggcaatg gtctccaaga cctctctctt ttctgcagct ttcaaggaac ctatcaagag
     2701 agccagtttc aaattgggaa aaaggttctg taaactctca aagtgttgct ctgcgaggat
     2761 ttctgttggt accattaggg cagcctgata acctgctgtc actgccgcaa acatggccaa
     2821 gccagcgact accgtttttc cactccccac atccccttgt aggagacgat tcatgtggtg
     2881 gtcggacttc atatcagtta aaatttcctg caaactcttt tcctgagctt gggtcagggc
     2941 aaaaggaaga cttactttaa ctgctgtcac tttttcctga gaccaattca gaaccagacc
     3001 acttccctga actctatttt cagacttgag catctgcagc tgcatttgga aataaaagag
     3061 ttcctcaaac tttatacggc gaagagcctg cttgtattct gccaaatcct ttggaaaatg
     3121 catagctcgg actgcctgac aacgggacat gagtttgtat ttgtctagta aagactgggg
     3181 cagattttct tctatcaaga ggtccagtcc ctgatcaaaa gccgtcttga tgaccttgac
     3241 cagactggcc tgactgattc cctgagccag acgatagaca ggctggaggt catcttctac
     3301 ctgagccaga accttcatcc cagtcagact agccttagcg cggtcccatt ttccaaagac
     3361 agcaagggtt gctcccaact ctattttatc agccagatag ggctggttaa agaaattcac
     3421 cgcaaaaacg acctctccct gcttgagact aaaacgcagg cgattgcgct tgaaaccata
     3481 atactggaca ctagcaggag tcactacctg accagaaaga actgccttct caccgtcttc
     3541 cagctccagc acctgcttgg ttttgaagtc ttcataacgg aaaggaaagt agagcaagag
     3601 atcttgcaag ttttcaattc ctagtttggc gtatttttct gctgactttg gtcccacacc
     3661 aggcaagaca tgcaagggtt gatgtagatt catgctccac tcctttcttt tctaataata
     3721 ttctctcgga atacggtcgc tgaggaggca aaccacctca tagttaatgg ttacgcggta
     3781 ggtcgctacc tgagttgcag tgatttcctt atccccattg gagccaatca aggttacctt
     3841 ggttcctagc ggataaagct taggcaatcg aatagtgatt tggtccatcg aaaccctgcc
     3901 gacaattggg caagcttggc catctaccaa gacagagaaa ttttgcatgt ctcttgtcca
     3961 tccatctgca tacccgattg gcacggtcgc gatgacttgc tcgctatccg cttgataagt
     4021 tgctccatag cccatgcaag ctccagctgg aactgtcttg acatgaacca gagcagactc
     4081 caaggtcaag gccggtatca aatcataagg caaatccaag accgctccac ttggattgag
     4141 gccatacatg gcatctccca tacgaaccgc attgaaaata gtctctacat gccaaagagt
     4201 cgttgcagaa ttgctagcat gaaccagctc tggaacttcc ttcatactag ctaaaatagt
     4261 tttaaaccgt tctaactggg cattaaaata gtcatctgat tcctcatcag cagtagcaaa
     4321 gtgggtaaag attccttcaa cacaaacacc gtgttgttgg agcaaatctt gagcctgctc
     4381 aacctcactt gcctctctaa aaccaatccg tcccatccct gaatcaatct tgaggtggac
     4441 tgtcaatcca gttaggtcca cttccttatc taagagtgct tgaatccact ccagtccagc
     4501 cactgtcaag gtgaagtcat attctttagc tagagcaaca gcttcgattt cagaaactcc
     4561 taaaatgagg attggcttgc tgagtccagc ttgtctgagt tcaatggctt catcgatatt
     4621 ggaaacgcaa aagccatcaa catcatcttg aattgccttg gcaacggcaa cagctccatg
     4681 accataagca ttggccttaa ccacagccaa cttgagcgtt ccttgaggga tatgagcccc
     4741 catttgctga atattttgtc gaatagctcc cagatgaatc agagccttgg ttggtctatg
     4801 tggactagct ttcatgattt tcctccaaaa tgacactggc tgtcacaaac tgatcggtgt
     4861 ggctgataga cagccaaatc tttcctgaaa atggtgcctg actaaaataa ggcgccccac
     4921 gttcattgtt caagacttcc aaatcctgaa aaccgagctt gctaatgccc gttcccatag
     4981 ccttggaaaa ggcctcctta gccgaccagc gaccagctaa atattctatt tgcctgcgtc
     5041 ctttgagact ggtgaagcgc tccatttcct gagcggtcag tacacgctta gcaaatcctt
     5101 catgtcgtgt aactgcgctt tctatcgaag ccaattcttc gatgtcaatt ccgtgtccaa
     5161 ctatcattct catcaaaagg agttgagatt ccccaactcc atccttttca cttattttgt
     5221 caaggtaaca taaatctctt ctaccaaggc ctctgtattt tcccaaccta ggcaagggtc
     5281 agtaatagag caaccaaaga tctctggttg gttttgacga ccatctgcta ggtaagattc
     5341 aatcataaat cctcgaaccg tctttttaat tttctcattc caatcacgat tctgcaaggt
     5401 ctggcgaaca attcgaatct gctccatata ttgcttgcct gagttatcat ggttggtgtc
     5461 aatgaggata aaaggatttt caagtcccat ggtttcatag cgttcaatgg cttggagtag
     5521 attttcatag tagtaattcg gcatataatt gccatactcg ttgactgctc cacggaggat
     5581 aacatgggcc aaaggattac ctgatgtctc aacttcctgc ccatgataaa ggaaggtttg
     5641 cttgttttga gcagcataga tggcgttaaa cataacaccc aaatttcctg aggttggatt
     5701 tttcatccct actggtgcat caatcccaga agccacaaag cggtgctctt ggtcttccac
     5761 agaacgagct ccaacggcat ggtagctgac caagtcatcc accaagatca gatttgacgg
     5821 ataaagcatc tcatctgccg ttgtcaaacc agtctctgta atcacgcggt agtgcaactg
     5881 gcgcacagcc tgcaagccat taatcaggct tggagcctta gaagtatctg gctggtgaac
     5941 taatccttta tagccgtctc cattggtacg aggcttagca gtatacacgc gcatgaccat
     6001 gaaaatctta tccgctacct tcttttgcaa ggcagataaa cggcgagcat attccaagac
     6061 cgcctcttca ttatcagaag agcaaggacc aatcaccaag agaatacggt catcttcccc
     6121 tgaaataata tctgccaatt ccctgtcacg gctttccttg agtctcaagg cttccgcaga
     6181 caattgggtt tcagccttga tgacttccat atcgatttct tgaccttttt caataaatgc
     6241 catcttattc tcctaacgtt ttgtaaattt ctctgacaag agcttctgtg ttatcccaac
     6301 ccaggcaagg gtctgtgata gacttaccaa atacttctgg ctcattttgt cgaccatctt
     6361 ccagataaga ctcaatcata aaaccacgaa cgaactgctt aattttttca ttccaagcac
     6421 ggttaatcaa ggtctggcgg acaattcgga tctgttcaat atactgctta ccagaattgt
     6481 catgattggt atcaatgatg ataaaaggat tttccaagcc cattttctca tactgggcaa
     6541 tggtatcaat taaattgtca taatagtagt tgggaatatt ttttccatac tcattaagag
     6601 caccacgaag aatagcgtgt gaaagcgggt tcccagttgt ttctacttct tttcctaaga
     6661 aaaggaaact ttgtttgttt tgagcagcat aaatcccatt aaacatgaca ttgagatttc
     6721 cagaggttgg atttttaaaa ccagtagaaa atcctgcccc acttgccaca aagcggtgtt
     6781 gctggtcttc aactgaacgg gcaccaactg ccatgtaaga aatcaaatca tctacaagcg
     6841 gaaggttttc aggataaagc atttcatcag cagttgtcat ccctgtttct gtgatgacac
     6901 gatagtgaag atggcgaacg gctttgattc cattgataag actaggcgct tctgtcgcgt
     6961 taggctggtg aatcaagccc ttatagccat ctccgttggt acggggtttg gcagtataaa
     7021 cacgcataac cataaagata cgatctgcca cttcttcttg taggactgcc aaacgcttag
     7081 cgtattcaag gacagcttct tcgttgtcag atgagcatgg cccgattacc aagagaattc
     7141 gctggtcttc tccacgtata atggcttcta gctcttgatc tcgctgtgat ttcctctcca
     7201 aagcctgacc ttctaatttt gacaaggcac gaacttcttc tatatttatt ttagagcttt
     7261 ttgctgtaaa taccataact catctcctta taaagcaaac ggatacccag taaaaattta
     7321 cttttcacaa gatatccgcc tctaaactat ctcattttat tgtcttttac cgtgacagtt
     7381 tttaaatttc ttaccagaac cacatgggca aagttcattg cgtccaatct ggctcaaatc
     7441 caaatcttct ggcatacttg cttggtgagc agcgatattg cgagtcgctg ttgtactgat
     7501 atgacgttct gcctgtggtc tttcttgttc atgaatttgt gctttcatca tcaagcgtgt
     7561 cacatcaaac tcaatcgaac caatcatatc attaaacata cggaaacctt ctgcctgata
     7621 ctcaacaaca gggttgttct gagcatagcc acgaagtcca accgcgttac gcaattgatc
     7681 aagggcatcg atatgatctg tccacttgtt atccaccact cgtagaatca aaactttttg
     7741 gaattcttta actgcttctt catcgcgtag ttttgaaacc tgactatcgt aaaccttcaa
     7801 ggaacgttgg aaaagctctt ccttgatggc cttatcagac aagcctgaca agtcttccat
     7861 cgtaatagaa tcttcaggaa gcaagttgta cttagcaaag ttcaaaattg cctctagttt
     7921 ttcatcttgt ttggcacgcg catgaccatc aacgacacgt tcaatcgtgc gtttgatcat
     7981 agactgaatt tcaggtgcca agtcacgatc tgcagtgatg acatcgtaac gttgagcata
     8041 gataatctca cgttgttcac gcatgacatc atcgtattga aggacttgtt tacgggtatc
     8101 gtagttattt ccttcgacac gtttctgagc tgcttcaacc tgacgcgtca acatgcgaga
     8161 ctcaatggcc tcttcagaca tgttgagacg ttcaaagatt cccttcaagc gttcagaacc
     8221 aaaacgtttc atcaaatcat cttcaagaga taggtagaat tgtgactcac ctggatctcc
     8281 ttgacgacct gaacgtccac gaagctggtt atcgatacga cgactttcat gacgttctgt
     8341 accaataaca caaagtcctc caagttcacg aacaccttca ccaagcttga tgtcggtacc
     8401 acgacccgcc atgttggttg cgatggtaac ggcaccacgt tgaccagcat tcatgatgat
     8461 ttgggcttct ctatagtggt ttttggcatt caagacttcg tgaggaacac cagctgcaac
     8521 caatttctta gaaatgtagt cactagtttc aaccgctact gtaccaacca agacaggttg
     8581 acccttttgg taacgagcct taacgtcttc gacaaccgct ttaaacttag attcgatact
     8641 tgcataaaga aggtctgagt ggtcaatacg ttgaacagga cggtttgttg ggattggaat
     8701 aacacgaatg ttgtagattt cacgaaattc ttcttcctca gtcttacctg tacccgtcat
     8761 accagacaat tttttgtaca tacggaaaag gttttggtac gtgattgagg cagatgtctt
     8821 ggtttcatcc tggattggca caccttcttt ggcttcaata gcttggtgca atccatcaga
     8881 ataacgacga ccttccatgg tacgacctgt aaattggtcg acaatcaaga tttcttgctc
     8941 ttcgctcacc acatagtcaa tatcgagaag catgatgtag ttggcacgaa gggcgttatc
     9001 gataaagtgg gtcaaagcca cgttttcgat gtcatagagg ttttcaagtt tgaagtagct
     9061 ttcagccctg tcaatccctg aatcagacaa accaatagtc ttagactgca catcgatgat
     9121 gtagtcatct ttgttcaaag attttacata gtggtctgcc atgtgataca actgactggt
     9181 ttcaaccgca ttggcacctg atacaatcaa aggtgtacga gcctcgtcaa tcaagataga
     9241 gtcaacctca tcgaccaagg catagttaag cggacgttgt accatgtttt cagcgcgaac
     9301 gaccatgttg tcacgaaggt agtcaaatcc gatttctgag ttagttgagt aagtaatatc
     9361 acactcatag gcttcttttt tctccattgg agatttggta gccaagttaa tccctactga
     9421 caaaccaagc caagagtaca attcacccat ctcagtcgcg tcacgttctg acaggtattc
     9481 attaaccgta actacgtgaa cccctttacc tgaaagggca ttgaggtata ccggcatggt
     9541 cgcagttaag gttttccctt cccctgtacg catctctggc acgtcaccat ggtgaagaac
     9601 aatccccccc atgacctgaa ccttataagg gaagagacct aggacacgtt tggcaccttc
     9661 acggacaacc gcaaatgctt cgtaaagcaa tgaatccagt gattctccat tttgataacg
     9721 ttccttaaat tcaactgttt ttgcttttag ttggtcgtca gtcaaagcag ccatttggtc
     9781 ttcgtatttg aaaaccttgt cagccatctt ttccagacga cggatttctc ctttatcatt
     9841 ttcgataatt gtttttaaaa tattagccat gtttttcctt actttaaatt ccgaatattt
     9901 tagaatgttc ctttaatttt agcacaatta ctgattattt tcaaggaaga atccccattt
     9961 tgaaaaggaa aaagaggtta gttttcaagc taacctctcc gacttttatg actgtttaat
    10021 tgccaaaaat cggcaaaatg gcaaatgtga taaataagtt aatccaaaga gaaagacagc
    10081 aaatcagtcc aaaaacaaag agactgactt tcttggacag caaggccatg agaatggaca
    10141 gaattccaaa agctagcaag attttctgta tgatgaagat gtcaatcctt acccccagaa
    10201 tcgctctatc ccaagggata aagaagaaag acagccagat cagcagaact aaaccaatat
    10261 aaaccttgga atagcgtgta ataaatgatt ttagatgtgc cataagccat ctcctaggat
    10321 tgtatatcct ttacatttgt atatgtccat tttcgacaac taatacatct gtacaaaggt
    10381 ctgaaatatc ttccgatatg tgcgacgtca ggataaccag accattttct tttttcaggt
    10441 aagataaaat gacctgtttg gttaacctca cactcttctc atccaaagca ttcataggtt
    10501 catcgagaaa gagtatagaa ggagaggaaa taaaggcttg aatcaaggcc attttttgct
    10561 ttgttcccaa ggataaatga cggtattcaa cgtcttcaaa ttcctgtaaa tcatagtatt
    10621 gaatccaata ggcaattctt ttttccgtaa ctttagatga aaaatacctt aacagttcca
    10681 aattttctct cagggataaa tgagataaaa actcgacttt ttcaattaaa attcctgcat
    10741 cctgaatata atgatttttt atcccgtaga ctttcccgtc ttgaagaact tttcctttgt
    10801 caagcttaat atagccagca agtaccttta aaagaaccgt cttgccagat ccattatcac
    10861 ctttaagtcc ataaattttt cctgattgaa acaccaaatt caactgattt aaaataggtc
    10921 ttttcccata aattttctgt ccatttataa tttcaagtct catcgtttat cctttcttaa
    10981 atttctcttc caagcgacta acaatcaaca taactaataa acttaagagt agtaaataca
    11041 ctgttacaat atgatccatc atccattctt gtcccacaaa tactaaaaaa tagagaaaaa
    11101 aggaaaaacc agcgcccgca ctaatcagtg ctatcagata agacagtagt aagtacaaca
    11161 tcattaactg agcaagtaaa aagaaaagtg cgactgtttt gaaatgaatt cctagcggaa
    11221 gtaaaccaag gaaccagaca aacaaatctt gagtaaaaaa tttagaaatg acaaccaatc
    11281 gtttccttgt ataatcgaaa aaggagcttg attgatagcg aatcaagtga tggtaatggt
    11341 ctgccaaatc actttcaagt aaaatgacag agagccatcc taccatgaaa agcgaaaggt
    11401 ttaacaagag tttggggatt tctaaattcg cttcagaata gtcattatag gaaaaaattg
    11461 aaatcaattc tctcttgaaa aagataacag catcctgctt ttgaaccgct gttgacaata
    11521 gatggtttat caaaatcatc atcagaacta tacgaagtag taaaacaatc tttctcttta
    11581 gcaaaatatt gttaaaattc ttaaacatta tcttcatatt tttcaagcac catgtaaggg
    11641 acaatataaa ggatataagg agtaaagagt ttcatcaaac ttacatcccc atagctagct
    11701 tgcatcaaac tcgtcatagg aaccatatag taaggcaagg cactatagag cagcatagaa
    11761 ccaagccaaa gaaacatcaa ataggtgatt gccgaacgag tcacattccc cacataatca
    11821 actatttgta aaaaatagat tgcattgatg aaaataccga ttagcaggac acaagtaaag
    11881 aacaaatagc tttttatctc tccatctagg agtctttgta aaccacttcc atcagaaaat
    11941 agagaattcc atccaagagg agaaaaagtc ccaaggaaat aggttataat tgcaattgtc
    12001 agcacagtca ctaaatatat caaacaaggg atacttgcaa cttgcaaagt caactttctt
    12061 tttaaccctg gatagctcac ttctcttcca atactcaatc gtaaaacttt atttttcagc
    12121 tcaatatatt gaaaacctag caaaacaatg atgattggaa taataaatga ttgataaaaa
    12181 cctagattga actggagaat acgaaaatct aatgctgatt ttaataagtc atttttaatt
    12241 gcttgtccat cgaatttagc tagatcgggc gcatgaatat caaaaaagaa ataagtcatc
    12301 aaaacgtcac gataaaccaa agcaagaaaa agcaaagtaa gcaagacata aacaaattta
    12361 tgccttgcca aagttaagag aggaatcttc ataaattata cctactttac gaattaattt
    12421 ggtgaccaac tacctgaaat ggcagctgat aaatcccacc aattttgtct tgccatatct
    12481 gctgcataaa catagccaac cgttgcccaa ttaccatgag ttgaacgagt accacaggtt
    12541 gttaacgatt ctccactacg agcttctcca ttagaattta ctatacgatg cttaacagtc
    12601 atgggatgta aatttctaca aggatttaag ttcatgatat attccgcacc ttcattttct
    12661 ttagtcaaat aacctgttct cttataactg gtagtaataa caaaattact aaaagcacct
    12721 atctgatttg cttctacgaa agtagttcca acagcactta tcattaaaac aggaataacc
    12781 attttcaata atttcttaat tttcattttt tctgtttcct ttcatttttt attcaagaag
    12841 attccttata acttctattt taaatataga cttattctaa acgatggtat atcatacaaa
    12901 ttcctccttt acttattata tatagactct aatttcttta tccccaaaac catgtttcaa
    12961 accagataag ttgaatccaa ctccaaatca aaaatccaga gtttttcggt aaattcttca
    13021 aatatttttt aaagcccatg actttttccc tcctttttga tataataata ccaccttttt
    13081 ctacgttttt tataaatgta gaaaatattc acatttacct aggaggaaca atatgagatg
    13141 ggattatgga caaattttta aagaaattcg aaagtcaaaa ggattgaccc aacaagatgt
    13201 atgtggacaa gtcatacatc gaacaactct aacaaatatt gaacacggta aagttattcc
    13261 cagttttgaa aacatggtat ttcttcttga acaaattgat atgagcttgg cagaattcaa
    13321 gtatatatgc aacgaatacc atcctagtaa aaggcgagat attattgtag agagccaaaa
    13381 tccgtctact tttcaagata ctagaaaaat ggttgaactc actgagaaat gtcaaaaata
    13441 tcttaagaca catcacgatg tccctattca aaatatctat cgtcatacaa aaattgtcac
    13501 agagttacga actaaaggat tcaaaaacaa ccacgtcttg aaagatttgt atgaagaaat
    13561 ttgggactat cttgaaccta tggatacatg gtacattagt gatttgaaat tgcttggaac
    13621 cattctcttt ttctttcctt ctgaaaatct tccccttctt attgatagaa ttatgaaaac
    13681 catcgagaaa tataaatact tccgagaaac aaaagcattt ttatcatctt ttttagccaa
    13741 tctctccact gtatattttc aacatcattt attcaaagaa tgtgaaacaa tcaccctaca
    13801 acttttggta ttagcagaag aattaaaaat atacgatatt cttggattct ctcaagtacg
    13861 cttgggaata ctacaacata actccgattt gattgataaa ggaataactt tattacgact
    13921 aaccaaagaa gaggcattag ttaaaatact cgaaaaagaa attaatgatt tttcaaacct
    13981 ataatttgta ataactctca tcattttatt atagtagatt gtaatagaat gtaatagaat
    14041 gtgaacgaat caattagggg atctaaagca ttttatacca atgttttata agttgtattg
    14101 tattattcca tattcaatcc actatacaag atgaatattt ctctcaagtt tcataatcaa
    14161 aataaaaatg actgtatcta tagctccata aacaaatcat agatacagtc attttttagt
    14221 tcctacacct tcctttatgc acacctttag atttccctag ttcccgcctc aagcgaatca
    14281 tttttttgaa aaagacatag gctaaccaat cactagcaaa agcgataagt agtaataata
    14341 gccaaatacc ccataacttg atatctgtca aatttctcaa gacgatattg aaaaacagaa
    14401 ctgaaaaaac tgtccaagca aggctaaaaa gagcatagag ggtgatgtaa atccagtaaa
    14461 aatagtaaaa aattgggaaa aatttacttt ctctattatc cttgtcaatc cagctgaaaa
    14521 agtaaaaaca gggtaataag attatcattt taaacaagtg ttccatcaca agcctccttt
    14581 tttaaattgt tttctttagt ttcgttctat taaatgttat taccaatata aaccttggaa
    14641 tagcgtgtaa taaatgattt tagaggtacc ataagccacc tcctacaaat agaaaccgat
    14701 ataaatcaat gccttccacc cttagacttc cctagttcct gtctcaagcg aaacatttct
    14761 ttgaaacagg aataagttaa ccaattcata ccaatagcta gcagaataaa aagaaaccaa
    14821 atgccccata acttgatatc tgtcacattt ctcaagacgg tattgaaaaa cagaactgaa
    14881 acaactgtcc aagcaaggct aaaaagagaa tagaagggga tgtaaaacca gtaaaaataa
    14941 taaaaaattg gaaaaaactt actatttctg ttggcctttt caatccagtt atcaaaataa
    15001 aagtacggtg ctaaaagtaa gaatttaaac aaatgttcca tcaccgacat cccccttctt
    15061 ttgatagcgt tttctattat tttattatat caaaaaaatc cggaactgtc attccagatt
    15121 ctactttttt atttgcgttt tcttgcgatg agatgaatcg gtgttccctc aaaaacaaag
    15181 gccttgcgga tttgattttc caagaaacgc aggtaagaaa agtgcatgag ttcttcttca
    15241 ttgacaaaga tgacaaaggt tggtggtttg gttgccactt gggtcgcata gaaaatcttg
    15301 agacgttttc ctttgtctgt cggtgttggg ttgatggcaa tggcatccat gatgacatcg
    15361 ttcaagacag ctgatggaat acgtgtattt tgactttcgc tgatttgctt aatcatctca
    15421 ggaagtttgt ggagacgttg cttggttaaa gctgatacaa agataatcgg tgcgtaaggc
    15481 aggtattgga actgctcacg gatatcttct tcccagtttt tcatagtgtg gttatctttt
    15541 tcaagcgtat cccacttgtt gaccacgata atcatccctt taccagcttc atgagcaaat
    15601 ccagcgatac gcttgtcgta ttcacgaatc ccctcttccg cattgatgac cattaagacc
    15661 acatctgaac ggtcaatagc acgcatggca cgcatgacag agtacttctc agtattttca
    15721 taaaccttac cagacttacg cataccagcc gtatcaatca tggtaaactc ttgaccatct
    15781 gtatctgtaa agtgggtatc aatagcgtca cgagttgttc cagcaacagg actggcaatg
    15841 acacggtctt ctcccaagat agcattaatc aagcttgatt ttccaacgtt aggacgacca
    15901 atcaagctaa acttaatgac atctggattt tcttcttcat attcatttgg aaggttttcc
    15961 acaatcgcat ctagtacatc ccctgtaccg ataccatgga cagatgagat aggcagtggt
    16021 tcacccaaac cgagagcata gaaatcatag atatcatttc tcatctcagg gttgtccacc
    16081 ttgttgactg cgaggataac tggtttgtgg gtcttataaa gcttacgagc tacgtattcg
    16141 tctgcatcag taattccttc cttaccagac acgacaaaaa cgataacatc tgcttcttcc
    16201 atggcaattt ctgcctggtg cttgatttgt tccatgaaag gagcatcgac atcatcaatt
    16261 cctcctgtat caatcatgct aaaagaacga ttgagccact cacccgttgc ataaatacgg
    16321 tcacgtgtca ctccttcgac atcttctaca atggagattc gctcaccagc gatccgatta
    16381 aatagggttg atttcccaac attgggacgt cctacaatgg caatagttgg tagggccata
    16441 atttctcact ttctacaata atttcttctg ttcaagattt tttctagttg agcttggttc
    16501 agcttgacca aactgttctg ctaggcgctg actccagctt gtggtcgcac gcgccccagc
    16561 atagtcagcc tgaacacggt cataagcttg gattgcctca gttgactgtt cttggtattc
    16621 ttcctcaaag acaacattct ctagtggcag tctcggtttc atatcatgat gttgatttgg
    16681 cacacccagt gccatcccaa agacagaata ggtgtagtca ggtaggttaa agagctctgc
    16741 cacttcttca gacttgtatc gaaccaaacc gataatcaca ccaccatagc ccaagctttc
    16801 agctgccaac aaggcgtttt gtccagcaag agctgcatcg accgaactaa tcaagagacc
    16861 ttccacacct tggggttgga aggtgtcggt atgaagtctg gctccctttt ctgctcggtt
    16921 caaatctccg acaaagagaa ggaaaacagc agactggcga atggcttctt gaggtaccaa
    16981 ttcatacaag gcatctttct tctcttgact tcgtaccaca atcacagagt aggattggaa
    17041 attcttccaa gatgatgcca tctgggctgc tgtcaaaatc tcatttaagt ctacttgggg
    17101 aatttcttgc tctttaaacc tgcgcactga agtatgagcc ttcatcaatt taatggtttc
    17161 tgtcatcgac ggtttactcc ttctaaacga gtctcctcag ccaaataacg gatgcgttcc
    17221 atgacccgtc tggcttccca ggtttcgtca tttccatgtt tcactttcgc aaaatgcttc
    17281 tccaaatctt caaagttgaa gttggatgtg aaaaaggtcg gtaaattttc ctgcatccga
    17341 tattggagaa tgacctgcag gatttcatca cgcacccaag cggtggattg ctcggcgcca
    17401 atatcatcta aaatcaggac ctcagacagc ttaatctcat ccaccaaggt cttaacattg
    17461 ccatcactga tagcattttt gacatcaatg acaaagctag gatagtggag gagagttgat
    17521 gaaacaccac gtttttctga taaatcatga gctaaggccg ccaccatgaa acttttaccc
    17581 acaccaaagt ctccatataa gtaaagacct tttcgaatag ctggatattg ctccacgaag
    17641 gctagtagct tttcaaaaac tggtaagcgc cccaaatcat ccaagtcaac ttgagccaaa
    17701 ctagctttct tgagactggc tggtagattg attaacttga gacggttctt aatagccgct
    17761 tctttttcag ccgcgattag ctcaggagtt tcttcatatg aaacatctgc atagccatga
    17821 ttcttaacca aaatcggctt gtagcctttg gcaatataat ccgtatcccc acggagaaac
    17881 ttgtcacgct cggtgatgta ctgattaaac ttggagatac tgcgatttaa ttcctctgga
    17941 gtcaaggatt cttgctggat aaaagccgca acatcagggt ccttcatgat tttctggacc
    18001 aaatcttgat aataaaaacg gctgggttga cgtttgagta cgtctccgac actttccatc
    18061 taatctcctc ctttttctaa tcgagctaat agttcttgct tcttacgttc tagttccaga
    18121 cgagtttcct cgctggtttc attcttatat tcaggattac tccatttagg aacattggtt
    18181 tttactgggg cagtctgatt ctgtttttgt gtttttgctt tctgtcctcg ctcacggatg
    18241 cgcaagactg ccttttctgc cgaatgaatc ttttgatagg catagtcatt ggctaccttc
    18301 atggcatatt tctcattgat atttgccgaa tcgaccttat taaaggtcaa taaaagaatg
    18361 atattgatga cttcgtccag caagcccaag ccagccatct gttgcaagag ttctctttct
    18421 gtttgggtaa tggttccctt gcgtgtttgc ttgatttctg ccaagaactg cagggcagtt
    18481 ttacttttgg cttctttgat aatggttgtt tccttaagac taaagtcaga ggaaactggt
    18541 ttttgagcaa ttttttcacg catgcgtttg gttgaaataa cctgagaaac agctgttgac
    18601 ttggccaatt gataggtttc aaaccaagtc catttcttct cctcggcaat agcaaagagg
    18661 tttaagacat cggactgctc atccgcaaaa cgaagtccat ctcgagccat cagctggcga
    18721 aaatgttcca agtcaaaatc attggccact ttcttcttga gaccaaggtc ttcttgactg
    18781 cctagttctg ccaattctgg aaagacttga ttgagtgaga caggtatttc ttcaccatca
    18841 gcactttcaa ctttcaaatc ctccacagca gagtcgccaa tctttttctc taagagtctg
    18901 cgataaacag gatgctccaa gaagtcttga ctagatagag gagcatggag ggctagctga
    18961 taaacatccc ccttttgata gagggtcaag agattaaaag cagataagat tttcaatgat
    19021 tttatcagtc tatccatccc aaagttgaga tgattgagga tacttgaaaa aagatattcc
    19081 tttctaccat tatcccaaaa actgattgta taaagataaa ggctcagtgc ctcctgaccg
    19141 ataatcggga ggtagcactg taccagagat gaggtatctt gcgacacccg attattcttt
    19201 agataagaaa aacggtcaat tggcttcatt tatctttcct ttttcttttt agaggactgg
    19261 gtgatttgtt ggagcaagct ctctaactca ctgacatcct taaaactacg atagacacta
    19321 gcaaaacgta cataggtaat ctcgtccaat tcagccaact cctccatgac gagtgaacca
    19381 atgtcctcac tttgaatttc attttcattt cgaccacgga gtttctgttc gatacgattg
    19441 actaccatgt tgatttcatc acttgacaca ggacgtttct gggctgagcg gataatccca
    19501 ttaaagattt tatctctgga gaattgttcc cgtgtgccat cttttttaac aaccactaag
    19561 gttctttctt ctactcgttc gtaggttgta aaacggtgtt ggcactcgtc gcactctcgt
    19621 cttctacgaa tggtgttccc ttcttctgct tggcgactat cgataacact tgacttggta
    19681 gccccacatt ttggacaacg catcctttcc ctccttatcg ttttcttttc attataccat
    19741 tttttaagcg attcccaaaa caattcttct ttttgcttga caagtttttt gttttgttgt
    19801 attatttaat taagacaaaa ggataagaga aaggagacta agatgtcctg gacatttgac
    19861 aacaaaaaac ccatctattt acagattatg gagaaaatca agcttcagat tgtttcccat
    19921 acactggaac ccaatcaaca acttccaacc gtgagggagc tagctagcga ggctggtgtc
    19981 aatcccaata ccatccaaag agccttatca gaccttgaac gagaaggatt tgtctacagc
    20041 aagcgaacaa ctggacgatt tgtgactaag gataaggagc taatcgccca gtcacgcaaa
    20101 caattatcag aagaagaatt ggaacacttc gtttcctcca tgacccattt tggctatgaa
    20161 aaagaagaac taccaggcgt agtcagtgat tatattaaag gagtttaagc ctatgtcatt
    20221 actagtattt gaaaatgtat ccaaatcata tggagcaaca ccagcccttg aaaatgtttc
    20281 tcttgacatt ccagctggaa aaattgtcgg ccttcttggg ccaaacggct caggaaaaac
    20341 aaccctgatt aaactaatta atggcctctt acaaccagat caaggacgtg tcctcatcaa
    20401 cgacatggac ccaagcccag caaccaaggc cgttgtagct tatttgcctg atacgaccta
    20461 tctcaatgag caaatgaagg tcaaagaagc cctaacctac ttcaagacct tctataaaga
    20521 tttcaatctt gaacgcgccc atcatctact tgcagacctg ggcattgatg aaaatagtcg
    20581 tctcaagaaa ctatcaaaag gaaacaaaga aaaggttcaa ctgattttgg ttatgagccg
    20641 tgatgctcgt ctctatgttt tggacgaacc cattggtggg gtggatccag cagcccgtgc
    20701 ttatatcctc aataccatta tcaacaacta ctcaccaact tctaccgttt tgatttctac
    20761 ccacttgatt tctgatatcg agccaatctt ggatgaaatt gtcttcctaa aagacggaaa
    20821 agtcgtccgt caaggaaatg tagatgatat tcgctacgag tcaggtgaat ccattgacca
    20881 actcttccgt caggaattta aggcctaagc aaaggagatt atttatgttt tggaatttag
    20941 ttcgctacga atttaaaaat gttaacaagt ggtatttagc cctctacgca gccgtgctag
    21001 tcctttctgc cctcatcgga atacagacac aaggctttaa aaatctacct taccaagaaa
    21061 gtcaggctac tatgctactt tttctagcta cagtctttgg tggcttgatg cttacacttg
    21121 ggatttcaac cattttcttg attattaaac gcttcaaagg tagtgtctac gaccgacaag
    21181 gctatctgac tttgaccttg ccagtttctg aacaccatat catcacagcc aaactaatcg
    21241 gtgcctttat ctggtcattg attagcaccg ctgtattggc tctaagtgct gttattattc
    21301 tggctttaac agctccagaa tggattcctc tttcttatgt gattacattt gtagaaacac
    21361 atctccctca gatctttctt acaggtatat ccttcctact aaatactatt tcaggaatcc
    21421 tctgcatcta cctggctatt tccattggac agcttttcaa tgaataccgt acagcactcg
    21481 ctgttgcagt ctacattggt atccaaatcg tcattggatt tattgaactt ttcttcaatc
    21541 ttagttctaa tttctatgtc aattcactgg taggactcaa tgaccatttc tatatgggag
    21601 caggtatagc cattgttgaa gaactcatat tcatagctat cttttatctc ggaacctact
    21661 acatcttgag aaataaggtt aatttgcttt aaataatttt tacctagata tgtaacatac
    21721 tcatagaaca aaagagacca ggcaaaaagt ctttacaatt agaaaacgca tagtatcaag
    21781 tgttaaaaat ccttgatatt atgcgttttt tgtgagctga cttatttcct ttcactatat
    21841 cgcaaaatga aataagaacg gaacgatggg attttggaat tcaaatcaat ttataagaat
    21901 gttttagaag taatattatc ctattccaga ttcagttcac tatacaattg agttttcaag
    21961 caacctgttt acataatgtg tacataatta ggttcgtgat tccacccttt tcacctttaa
    22021 aaacctcgct ttcgcaaggc tcttctattt ataagataag gcacgtttaa aggttttcca
    22081 aatccctaaa tcatccgttt gaagaacgag actagcatac atgcgtccga taaatcctgt
    22141 tgctaccacc gcaaaaatca ctgtaatagc aagtgaaatc catgcttccg ctccctccgc
    22201 atagccatta atcgttcgaa acggcataaa gaaggtcgaa ataaagggaa tataagaacc
    22261 aatcttcaag aggagattgt caccagctgc acctagagct gtcactccaa aaaaaccacc
    22321 cataatcaaa atcatcaaag gcgacaaggc tttccctgag tcttcaggac gagaaaccat
    22381 agatcctagg aaggctgcca agactacgta catgaaaaga ctgatcaaaa taaagagcaa
    22441 ggtattcagt gagatagcat ctcccaagtg atccaaaata ccagactgag ccaagaatgg
    22501 caaatcttta aagagcaaaa cggcagccag accacctaca acatagatcc caatatgcgt
    22561 taaaatcact agaaacagag ccatcatccg cgcatagaaa tagtgacttg cccttatgct
    22621 agaaaagacg acttccataa ttttggtgcc tttttcactg gcaacttcct gagctgttac
    22681 acccgcatag gtaatcagaa tcatataaag aaagaatcct aaggcacctg ctgcaattgt
    22741 ttgaataaac tttttatttt ccttggcttc atcaatcttt tctgtgaatt gaattgtctg
    22801 cgctaagcgt ttttcctgct cttgagacaa ggaagcagtt gaacgattaa gctgattttg
    22861 cagttcattg agtgtacctg taacctcaaa tttaattcca ttttcaagcg atgtttcgcc
    22921 atgataaact gcctttagaa cactatcttc ttgatcaatg gtcaaataac cttttaattt
    22981 ttcttcttta attgcttctt tggcacttgc ttcgtcttta tagtcgaagt taacaccatt
    23041 tacattcttc agtccttctg ctacagatgg cactgttgtc actactgcca ctttattatt
    23101 tttagccata gaagaacctt ggagatgccc aattcctaca gagattccta aaaagaggaa
    23161 cggcgaaatc accataaaga agaaactcca tgactcgaca tgtcgaagat aggtttcctt
    23221 gattacaacc cacatatttc tcatacttcc actcctgatt ctagtttaaa gatttcatcg
    23281 atagttggcg cttgttggtc aaatgttgcg atatattgac cttgagtcaa gattgggaag
    23341 agttcccttc cagcgctctc atcctccaaa atcaatttcc aactgccttg tttggtcaag
    23401 ctcacctgtt tgacatgagg aagattttcc aattcttcct tgcttcgttc acttgaaaca
    23461 aagagacgcg ttttcccgta ttgattgcgg acatcctgaa ctggtccgtg caagaccaca
    23521 cggccatctc gaatcatcag aatatcgtca caaagttcct caacattggt catgacatgg
    23581 tcagaaaaga taatggttgc tccgcgctct ttttcctgaa aaatgacttg tttgagcaat
    23641 tctgtattaa ctgggtccaa tccactaaaa ggctcatcca agataatcag gtctggttca
    23701 tgaatcagag taataatgag ctgaatcttc tgctgatttc cttttgacag actcttgatt
    23761 ttatctgtca gctttccttt tacttccaac ctcttcatcc attgagggag tttttctttg
    23821 acttctttgg catccatgcc ttttagagtc gccaagtagc gaacttgttc aagaactgtc
    23881 aatttaggca tgagactgcg ttcttcaggc agataaccaa tccgagcata gatctcctga
    23941 cgaatatcct gaccatccag accgatttct ccctgatatt ctaggaattt taaaatacta
    24001 tggaaaatcg ttgtttttcc agcaccattt tttccgacta gtcccaaaat acgacctggt
    24061 cgcgcttgaa agtcaatacc aaacaaaact tgcttggatc caaaactttt ctctagactt
    24121 cttacttcta gcatctttca cctccgaaat ttcttgcact cattatactc ctttttgata
    24181 gcctttacaa tgttttttgt ccatttttag aagactattg ctgtgtaaaa tatggcctgg
    24241 agcactttta tactcaatga aaatcaaaga gcaaactagg aagctagccg tagactgctc
    24301 aaagtacagc tttgaggttg cagataaaac tgacgaagtc agctcaaaac actgttttga
    24361 ggttgtggat agaactgacg aagtcagtaa ctatacgtac ggcaaggcga agctgacgtg
    24421 gtttgaagag attttcgaag agtattagtg ataaatccat tatacagcag caaacttaat
    24481 ttataccttc cgctcctcaa ctgtctattt ttaatcctga attgttattt gagtaactcc
    24541 tttttcctcg taaagttttc ttcctctaaa acttctggaa aaaggctaat agtttcagac
    24601 aacattttta taagaaacaa gttcatctgt catttcaaga aggagtaatc ctttatctac
    24661 taatggacgg aacagaattc aaccgcttgt ccgatatgtt ttctaaggat tatatagtaa
    24721 aatgaaataa gaacaggaca aattgatcag gacagtcaaa ttgatttcta acaatgtttt
    24781 agaagtagat gtatactatt ctagtttcaa tctgctatat ctattatgca cacccctata
    24841 ggatctaatg aaaatcacaa caggctcatt catagatagt tacctcagga aactaagaaa
    24901 acgactacaa aggaagtcgc attcatcgaa aagtggatta acaactatcc taaaaaatgc
    24961 ttgaactaca agtcccccag agaagacttc tggatgacta acttgaactt gaaatttagc
    25021 aataattaat tcaccatcta actatattta gtaattattt cagaactgat taatattaaa
    25081 attaactaac aattcaaagg attcatacta gccataaatt acgtccatca gagagagact
    25141 cttactactt ttagatttta gtctttctag cttcagaata catctaaact ttagggaaaa
    25201 tgactattcg aaagcgcgaa tgcctcaaaa ttatctcaga taagctattc gaaacttaga
    25261 atgcttttaa atttatggaa ttgcgattat tcgaaaccta gaatgcatat aacctttagt
    25321 tgacagacct attctaagtc tcgaagggct atttactttc tattccttat caaaaaagac
    25381 tcattccccc tttctcctcc aaaatatggt atagtagaaa tatactatct atgaggagtt
    25441 tacatgtcac aggataaaca aatgaaagct gtttctcccc ttttgcagcg agttatcaat
    25501 atctcatcga ttgtcggtgg ggttgggagt ttgattttct gtatttgggc ttatcaggct
    25561 gggattttac aatccaagga aaccctctct gcctttatcc agcaggcagg catctggggt
    25621 ccacctctct ttatcttttt acagatttta cagactgtcg tccctatcat tccaggggcc
    25681 ttgacctcgg tggctggggt ctttatctac gggcacatca tcgggactat ctacaactat
    25741 atcggcatcg tgattggctg tgccattatc ttttatctag tgcgcctata cggagctgcc
    25801 tttgtccagt ctgtcgtcag caagcgcacc tacgacaagt acatcggctg gctagataag
    25861 ggcaatcgtt ttgaccgctt ctttattttt atgatgattt ggcccattag cccagctgac
    25921 tttctctgta tgctggctgc cctgaccaag atgagtttca agcgctacat gaccatcatc
    25981 attctgacca aaccctttac cctcgtggtt tatacctacg gtctgaccta tattattgac
    26041 tttttctggc aaatgctttg acacgtaaaa aatccgtttg gtttcccaag tggattttta
    26101 aagcgtagat taactatagc ttgatactaa atatactttg gtatggaaat catgcatatt
    26161 tttcgatagt gaagcgagga cttacctagc ctttccaccg tgatagaaac acctgaaatc
    26221 taatggtttc aggtgttcgg aaactttgag cctagtgtct caaagtttag gtatggaatt
    26281 tcgaagaaag tcgctaccgt ccgtaatcac ttaaggaaag gctcaaaaat attgttttca
    26341 accacaaaat ccgtttggtt tcccaagcgg attttgtgct ttattttgaa acttcttttg
    26401 caagaacaaa gttcccaagt gtggcagaac catttcctgc gactgctggc gtcacgatat
    26461 agtcacgcac atctggtact ggtaggtaac cattaagaag agatgtaaat ttctcacgga
    26521 cacggtccag catatgttgt tgagccatga cccctccacc aaagacaatc acgtctgggc
    26581 ggaaagtcac tgtcgcatta accgcagctt gagcgatata gtaggcttga acatcccaaa
    26641 cagggttgtt gagttcaata gtttccccac gtacacctgt acgagcttcc aaacttggac
    26701 cagctgcata gccttccaga catcccttat ggaaaggaca aacaccctta aactcttttt
    26761 caatatccat tgggtgtcta gcaacataat aatgacccat ttcagggtga cccacaccac
    26821 cgataaactc accacgttgg atgacgcctg caccgatacc tgtaccgatt gtgtagtaaa
    26881 ccaagttttc gatacgacca ccagcattgt tacgggcaac cacttcaccg taagcagagc
    26941 tgtttacgtc tgttgtgaag tacattggca cgtttagggc gcgacgaagg gcaccaagca
    27001 agtccacatt tgcccagttt ggttttggag tcgtcgtgat aaagccataa gtttttgagt
    27061 ttttgtcaat atcaatcggc ccaaatgaac caactgcaag accagcaagg ttatcgaatt
    27121 ttgagaagaa ctcaatggtt ttatcgattg tttcgattgg agttgttgtt ggaaattgtg
    27181 ttttttctac aacgttaaag ttttcatcac cgacagcaca gacaaacttt gtaccgccag
    27241 cttccaagct tccatataat tttgtcatga taaacctctt gtttttattt tctttattat
    27301 agcatacttc gaaagtctaa atgtctctat tttttagatt ttcctctgta aatcttacta
    27361 tctaataaaa acgaacaaac atgtcatttg ttcgttttca cattagagag gattgattag
    27421 attttcactt cgatcacagc atcccccttc gcaactgaac ctgttgcgac tggagctact
    27481 gaagcgtagt cagctgtatt tgtaacgata accattgttg tatcatcaag tccagctgta
    27541 gcgattttat ttgagtcaaa tgttccaaga acatcgccaa ctttcacctt atcaccttga
    27601 gcaacttttg cttcaaaacc gtcaccgttc atagatacag tgtcaatacc aacatgaatc
    27661 aaaacttcag caccatttct tgttttcaaa ccaaaagcgt gccctgttgg aaaggcaatt
    27721 gaaacttcag catcagctgg tgcatagacc acgccttggc ttggtttcac agcgatacct
    27781 tgtcccatag ctccacttga gaagactggg tcattgacat cagcaagagc gacaacatca
    27841 ccgacgatag gagttacaag tgtttcattt tgaagagctg ctggcgcaac ttcttctttt
    27901 tcttcagcca cttcagcttg ttttgcagct gcagttgcgt ctacttcatc ttcgtaacca
    27961 aacatgtaag taagagcaaa accaagggca aatgatacag ctaccataag aaggtattgt
    28021 ggaagttgtc cgttaccaac ataaagcatt gtaccaggga tgatggtgat accattacca
    28081 gtaccagcaa gtccaaggat agaagccaat ccaccaccga ttgcaccagc aatcaatgaa
    28141 aggaagaatg gtttacggaa gcgcaagttc accccgaaga tagcaggctc tgtaatacct
    28201 aggaaggcag aaagagcagc cgggaaagca agtgttttca gttttggatt ttttgtttta
    28261 acaccaaccg caacagtagc agcaccttga gctgtcatag cagctgtgat gatagcgttg
    28321 aatgggttag catggtcagc agcaagtaat tgcacttcaa gcaagttgaa gatgtggtgc
    28381 acacctgaca cgacgatcaa ttggtgaacc ccaccaatca agaaaccacc aagaccaaat
    28441 ggcatgctaa gaatcgcttt tgtagcaata aggatgtagt tttcaacaac gtggaaaact
    28501 ggtccaatga caaagagtcc aaggatagac atgaccaaaa gtgtcacgaa tggtgttacc
    28561 aagaggtcaa tgacatctgg aacaaccttg cggacagctt tttcaaattt agctccgaca
    28621 accccgatga tgaaggctgg aagaacggaa ccttgcaaac caacaacagg gatgaaacca
    28681 aagaagttca tcgctgttac ttcaccacct tgagcaactg cccaagcgtt tggaagtgag
    28741 ccagagacaa gcatcatacc aagaacgata ccaacggcag gatttccacc aaatacacgg
    28801 aaggttgacc acacaaccaa acctggcaag atgatgaagg ctgtatctgt caagatttgt
    28861 gtgtaagttg caaagtcacc tggaagtggc atttcaagag cgttgaaaag accacgcaca
    28921 cccatgaaga gacctgtcgc tacgataact gggatgattg gaacgaaaac atcaccaaaa
    28981 gtacggatag cacgttggaa ccagttccct tgtttagcaa cttctgcttt catgtcatcc
    29041 ttagatgatg ttggtaatcc aagtacaaca acttcatcgt acattttgtt aactgtacct
    29101 gtaccaaaga taatttggta ttgccctgag ttaaagaaag caccttgaac tttttccaag
    29161 ttctcaatca cttctttatt gattttctct tcatctttga ccatgacacg tagacgtgtc
    29221 gcacagtggg caacactatt gacattttca cgtccgccca aggcatcgat gacttttttt
    29281 gcaatttcct gattgttcat ttgcaaaaat ctccttatat aacattttgt tcttgtttga
    29341 aagcgatttt attcgccctt acgactatta ttttatcatg ttttaaaaat atgtcaagcg
    29401 ttttgcagaa aaaatattct atctacttag tgggcaagct ttagattgat tgtttttgac
    29461 tgtttcatca ggaatttctt gaaaaataag tttgaaacct tggttaaaaa gtcttttatt
    29521 tcattatctt tcacattttc gtaaaaattt gattgatttc ctgtatttat tttatgataa
    29581 tcgtttgaca gttttttctc ttttttaaca taaagggctt gcatttttta tcgaaaacag
    29641 ttactattaa aagtgataag atttttggag gaatgaatgg aatggacaac tgagcgtcgt
    29701 tacagacttt atcaagattg gacgcaagaa gaaattcaac atataaagga aaatatggca
    29761 caatctccat ggcatactca ttaccatgtt gagccaaaaa caggacttct caacgaccca
    29821 aatggctttt cttactttga tggcaagtgg atcctctttt accagaattt tccttttggt
    29881 gcagcccacg gtttaaaatc ttgggcacag ctagaaagtg atgatttggt tcactttaga
    29941 gaaactggag tcaaagtttt gccagatact ccattagata gtcacggtgc ctactctggt
    30001 tctgccatgc aatttggcga taacttattc ctattttata caggaaatgt tcgcgatgaa
    30061 aactggatcc gtcacccata ccagatcggt gctttgatgg acaaggaggg taagattaca
    30121 aagattgaca agatcttgat tgaccagcca gcagactcta ctgaccactt ccgcgatcca
    30181 caaattttta actttaaagg tcaatactat gctgtcgtcg gtggacagga cttggagaaa
    30241 aaaggcttcg tccgtctcta caaggctgtc aataacgact acacaaactg gcaagcagtt
    30301 ggcgaccttg actttgctaa cgaccgtact gcctacatga tggaatgtcc taatctggtc
    30361 tttgtagagg aacagcctgt ccttctctac tgtccacaag gattggataa gaaagttcta
    30421 gactacgata atatctttcc aaatatgtat aagattgggg cttcctttga ccctaaaaat
    30481 gccaaaatgg tagatgtgtc tcaacttcaa aacatggatt acggtttcga agcctatgca
    30541 actcaagcct tcaacgctcc tgatgggcgt gctctagcag ttagctggct tggtttgcca
    30601 gatgtttctt acccatctga ccgttttgac caccaaggaa ccttctcttt ggtcaaggaa
    30661 ctcactatca aagacgacaa gctctaccag tatccagtcg ctgctattaa ggaccttcgt
    30721 acttctgaag aagccttctc aaaccgttcc caaaccaaga acacttacga acttgaactc
    30781 aacttggaag ctaatagcca gagcgagatt gtcttacttg ctgataaaga aggtaaggga
    30841 ctttcaatca actttgacct tgtaaacggt caagtgacag tggatcgtag ccaggctgga
    30901 gagcagtatg cccaagaatt tgggataact cgttcttgcc ctatcgagaa tcaggctact
    30961 actgctacaa tcttcatcga taactctgtc tttgaaattt tcatcaataa aggagaaaaa
    31021 gtattttctg gtcgtgtctt cccacatgcg gaccaaaatg gtatcctgat caaatctgga
    31081 aacccaactg gaacttacta tgaattagat tatggtcgca aaactaactg atgtcgccaa
    31141 acttgcaggc gtcagtccta ctaccgtttc tcgggttatc aataaaaaag gatatctatc
    31201 tgagaaaacc atccaaaaag tcaatgaagc catgcgagaa ttgggctata aacccaacaa
    31261 cctggctcgt agtctgcaag gaaaaccagc taagttaatc ggcttgattt tccccaatat
    31321 ttccaatgtt ttctatgcag aattgattga taaattggaa caccaactct tcaaaaatgg
    31381 ttacaagacc atcatctgca acagtgaaca tgattctgag aaggaacgtg aatacatcga
    31441 aatgttggaa gccaatcagg tggacggcat catttctggt agtcacaacc taggaatcga
    31501 agactacaat cgtgtgacag cgccgattat ttcctttgac cgaaacctat cgccagacat
    31561 ccctgtcgtc tcctctgaca actatgctgg tggggttctt gctgcccaaa ccttggtcaa
    31621 gacaggtgcc cagtctatca tcatgattac agggaatgac aattccaatt cgccaaccgg
    31681 actgcgccac gctggttttg catccgtact cccaaaagct cctattatca atgtttccag
    31741 tgacttttct cccgtcagaa aagaaatgga aatcaagaat atcttgaccc gggaaaaacc
    31801 agatgccatt tttgcttcgg atgatttgac agctattctg gtcattaaaa tcgctcaaga
    31861 attgggcatt tctgtcccaa aagagctcaa ggtcatcggc tatgatggga cctactttat
    31921 cgaaaattac taccctcaat tggctactat caagcaacct ttggaagaga ttgcttgtct
    31981 cactattgat cttctcttgc aaaagattga aggcaaggaa gtcgccacaa ctggttactt
    32041 cttaccagtt acgctattac caggaaaaag tatttaaaca caagaaaact cagaccgatt
    32101 cgtctgagtt tttatgatct taaattttcg agatagcgct gggctgtctc taggttaaag
    32161 gttttatctg agatgaggcg ctctactagg ggagcaactt cagattcact agccccagct
    32221 aggagagcta gggatttggc ctgtagtttc atgtggcctt gctggatgcc cgtacttacc
    32281 aaggctttga gggctgcaaa attttgagca agaccgatgg acacgataat ctgggctaat
    32341 tctctggcag aaggatttcc tagtagatca tgactgagag ctacacgtgg gttgaggccg
    32401 atagagccac ccttagtcgc tacaggcatg ggcagggtca tctcaccgac caattcttct
    32461 ctttcaaggt ccagcgtcca gcagctaaga ccttgatagc gtccatctcg actggcaaag
    32521 gcatgggccc cagcttcgat ggcacgccag tcattaccag tggcaatcaa aatcgcatca
    32581 ataccattaa aaattccttt attatgagta gcagctcggt aaggatcagc ctgcgcaaac
    32641 tgactagcca acgcaatttt ctccgcaatc tctcgtcctt gatccttttg gcggctcaag
    32701 tagcgaaagg cgatgcgaca gcttgcagtc accagagaat cagtcgcgta gttggacagg
    32761 attcccatga gactctgtcc ctgactgagt tcttctaaga ctggtttcaa ggcttccagc
    32821 atggtgttga gcatattggc acccatggct tcctgggtat cgacatgaat ataaacaacg
    32881 agaaagtctg gttcgccttt tatctgctcg acatgcagat cacgcgcccc acccccacgt
    32941 ttaacgatag aaggataggc ttgattggca agctccaaga gctccgcttt cttgctggca
    33001 atcttctctt gcgctagttt aggattagca acttgataaa gggctacctg cccaatcatc
    33061 tggcgctgat ggacttgtgc agtaaaacca cctgcacgct tgatgatttt gctggcatag
    33121 ctggccgccg caaccacaga gggttcttct gtcacatagg gaacggtgta ttcctgaccg
    33181 ttgacaagta cctccggaac cagcgaataa ggcagagaaa aagttcccac cacattctca
    33241 ctcagctggt ctgccacagt cacactcatc tgttcatcct tctccagact agcttgtctc
    33301 tcaggactaa ggagcgcctg agcttttagc agctcgaggc gctcttggta tgatttttta
    33361 gaaaatccat tccaacttat cttcattatt tttcaacctt gctataacgg cgttggtggt
    33421 caagaatttc aaccaaggca aaatcttgat tttcatagcc agcaaactgg gcagagtttg
    33481 tttcatccaa gtttacttcc tcaaaaaaga ccttttcata gtctgcaacg gatagggcag
    33541 ttcgttggtt gagcttgttc aagcggtctt tatccaaata agcttcatat ccttcaacca
    33601 attcaccact gaagaactca gccacagctc cacttccgta actataaagg gcgattttat
    33661 ccccagcttt caagctatct gtattttcca agagagacaa aagtccaagg aaaagtgaac
    33721 ctgtgtagat attccccacc ttttgactgt agagaataga ctggtcaaaa tgcttttgta
    33781 agaggtcttt tttctcttga ggcaggctct tatccatgat ttttttcaag ccttttagcg
    33841 ctaatttagg ataaggcaag tggaaacaaa cagccgcaaa atcatccaaa gtaagctggt
    33901 agcgtttttg atattcaagc caagtcgttt tcaaactatc caagtattgt tgggtagaat
    33961 agacaccatt tacataagga gttgtcgagt aatttggtcg ccagaaatcc atgatgtcac
    34021 gggtctgagc tacattgtca ttattaaagg ccatcatgcg tggattttgt gtaatcaaca
    34081 tagctacact tccagcacct tgagttggtt ctcccggagt ttcaatacca tatttggcaa
    34141 tatcactggc aatgaccaag accttggact ccggagaatt ttccacatgc aatttggcat
    34201 aatggagggc agctgtcgcc ccatagcagg cttctttaat ctcgaaacta cgagcaaagg
    34261 gctggatgcc cagcaagcca tgcacaaaga cggccgcagc cttactctgg tcaattcctg
    34321 actcggtagc cacaatgacc atgtcaactt cttgtctttc ttgctcagtt aaaatagagt
    34381 cactagcact ggccgccaag gtcacgatgt cctcagttag gggcgcaata ctcaattcct
    34441 tgagtaagag tcctttactt aatttttcag ggtcaattcc cctcgcttct gctaagtctt
    34501 gtaatttcaa gacatattga ctggtcgcaa aaccaatctt atcaataccg attgtcatat
    34561 ttacctctgt tttatcattc atgtaaaaaa tcgttctata ctattttatc acaaatggca
    34621 gtaaaagaga gaaaaaagac ttgattcacc aaatcaagcc tcttattggt catcatttta
    34681 aagaatgatt agttgctaga gagttcaccg atataagtag ctttataagc tccattcaca
    34741 gttatcagct cctggaggat caaatttcct gagtaaatcc ttcccatctc atctacaaat
    34801 ttttgataaa actgactgat cggaatttct ctgacatcct tatcaaatgt cttatcaagt
    34861 gttttactaa ccttctcagc aatcaattga tgctcttgcc atccactttg aaactctgag
    34921 cccgaactag aaaccatgac tgggataaac aacaaggtca gtagatttac agacaataag
    34981 gaaagtagta gacttcctgc aaaactagaa tcctagttca tgattgataa tgccagcaat
    35041 caaattcatt cgtaatccga agcgtttacg atgatttcga taggttgttg aaaacatttt
    35101 aaacgttttt actttggcaa agatgttctc aaccttgctt ctctccttag atagcgcatg
    35161 gttacaggct ttatcttcaa ctgttagcgg cttgagtttg ctggatttac gtggagtttg
    35221 tgcttgagga tatatcttca tgagcccttg ataaccactg tcagccaaga ttttaccagc
    35281 ttgtccgata tttctgcgac tcattttgaa caacttcata tcatgacaat agttcacagt
    35341 gatatccaaa gaaacaattc tcccttgact tgtgacaatc gcttgagcct tcatagcgtg
    35401 aaatttcttt ttaccagaat cattcgctaa ttgttttttt aggacaattg atttgtactt
    35461 ccgtcgcatc aatcattacc gtgtcttcag aactgagagg agttcttgaa atcgtaacac
    35521 cacctttgaa caagagttac ttcaacccat tggctccgac ggagtaagtt gctttcgtgg
    35581 ataccaaaat cagccgcaat ttcttcataa gtgcggtatt ctcgcacata tagaaagcgt
    35641 tgttaattta tttatctcat ttttcagaaa attcttttat ttctgtaaag tctacgatac
    35701 tcgatgtgtt tttatataat gatacagtct gagaatcact gttccgctag ccattccaat
    35761 agagattacc aaagccaaca tgacaaccaa ggtcgcactt gccagtgctt tattatagtc
    35821 ccctgtcaca aaaaaggcag ttgttcggta ggagagataa cctggaacca gcggtgccaa
    35881 aatggccaag ataaagacca cagcaggtgt cttataaaga atacttaaaa tctggctgac
    35941 acaagaacca ataatggctg caatgaaggt agctacaatg acattggtcg gttccttgag
    36001 caagagatag attagccaga cagtcatgcc caaaatccct ccaggtaaga gcatagaccg
    36061 ttgcacattg agtacgatta aaaaagtgat aatggcaaga aaacttgcta ctgcttgtaa
    36121 taaaaaggtt gttagtgtca tattagttca tcaataccaa ggcgacagaa gttcctgccc
    36181 ctaaagcgag ggtaatgagc agggattcaa acatcttact cataccagag tttatgtggt
    36241 tggtcataat atcacggacc gcattggtca aggcaatacc tggtacaaac ggcatgaccg
    36301 caccagctat aatcaaatct gccgttgaag gaaaacctgt gtagcgagcc caaaactggg
    36361 caattatccc aaagacaaag gctccagcaa aggctgtcac aaagggaatt cggataaatt
    36421 tttccacata gagggaaaag gcaaaaccaa ataaggtcgc cactcctgcc ccaagtgcgt
    36481 cgtagatatt tccgctaaac ataactgaaa agaaaggagc actaaaggtc gcagccagag
    36541 ttacctgcaa cttagtatag ggaaggggtt tggcttgcaa ggccgtcaat tgcttaaagg
    36601 ctgtttctaa gtcaatctgc cccccaacta gctgacgaga aatctggttc acatcgcaga
    36661 ctttttcgat gttataagaa gaggaggtca cgcgcttcat gcgcgaaata ttggtatttt
    36721 caatagagaa aaagatagcg gcaggcatgg caaggacatt gcaatccaca atcccctgcg
    36781 aatgcgcgat tcgaatcatg gtatcttcta cacgatggat ttctgagcca cttttaagga
    36841 gaatagtccc cgctagcata atcacatcaa tgacggcatt taattctttt gattcttcca
    36901 tgctttcctc cttttatcaa ctccctctat tctatcacaa atccggactc aaaaaaaatc
    36961 tttgccatga aatcatgaca aagattgatt actcattttg attatccatc tgcttttaag
    37021 gagtagctga agttgtttta ggtttgtaga ttgaaatctt gactctagtc ttatttaggt
    37081 ctaccttttc acctgctcta ggactttgtt caacaaccat gccttctaca ctacctgcag
    37141 gcgctgtcgt cacttctaca acttctatat tagcttcctt aatcccaaca atttgaatca
    37201 aattgttctt agtaaactcc aagctggaac caatgtaact cggcatggca acacttgtaa
    37261 cttttttagc tactgtcaag acaatttgag taggtttact cacatcataa gtcgttccgg
    37321 cacctggact ttgtttcata atcgttcctg gttcgctttc gctggactct tcttcctcta
    37381 tcttaatcaa attctcagga accttcttct gcttgagttc tgagattact tctgtagagt
    37441 tccgtccaat atagttccct aattgaatcg tcgtagcttt tttagctact gtcaaaacaa
    37501 tttgagttgc cttgctcaag tcataggtcg taccttctgg tagactttgc ttcaagaccg
    37561 ttccagcctc actctcattg gactcttctt cctcaatttt aatcaaatta tctggaactt
    37621 ttttctcttt taattccgcg ataacatcag aagatttccg gccgacataa ttactaattt
    37681 ggaaggattg tttgcctgat gagacaacca gattgatttt cgttccttct tttcgaccag
    37741 ttccagcgcc aggatctgta cggataatcc gcccttcttc caccttttca ctagcctctg
    37801 tcttctcctc accaatctca aaattggctt ttttgagcgt tgccttggcc tctgcaactg
    37861 tctgacctgc cacatccgga atggcaatgg ttgcaggagt tctggataag atccaaataa
    37921 gagaagctgc caccaataca aggctggcca acaaaatcag gtaacgcatc ttaaatctat
    37981 gttttttcgg tgcttgtggt tggtaagttt cctctgtcac agcctggctt gggtttttga
    38041 ttgatttgtg ttctgtctgc gcttgaacct taggaataga tgtcaaggta ctctgagaaa
    38101 ccttcggcaa ggtcttggta tctgccttgc tcgtttcatc aaagattaac ttactttcat
    38161 ttctacgatt gtaggacaag ctactagaca agtccacata catctctgaa accgatcggt
    38221 agcgattggt caacttttta gcagttgcct tgataataac attttctaaa gcctgaggta
    38281 cagatggatt ttctgcaata acggacggca ggggtttctg gaaatgctgg agggcaatgg
    38341 tcaccgcgct atccccgtca taagggatat ggcctgtcaa catctcatag aaaataatcc
    38401 ccatggcata gatatcactc tgcacagtcg ccttagaacc acgcgcctgc tctggtgaca
    38461 agtaatgaac tgagcccaac atcgagttag tctgggtcag acttgtctct gcaaaggcta
    38521 cagcaatccc aaagtctgtg accttggcag tcccatctgg tgtcaaaagg atattttgag
    38581 gtttcaagtc cctgtgaaca attcctcgag tatgggccaa gcgcatagcc aagagaattt
    38641 gtcccatgat acggacggct tcttcattag aaagaggata atgttccttg atatagcgtt
    38701 tgaggtctag tccagcaaca tactccattg caagatactg ttgaccgtct tcctcaccaa
    38761 tatctgttat ccgaacgata tgaggatggt ctagatctgc catagctctc gcttcacgct
    38821 gaaaacgagc tacagctatc gggtccgtct ggtagttggt cctcagaacc ttcactgcca
    38881 cttcttcccc atctaagatt aagtctttgg ctaggtaaac atccgccatg cctcctcgac
    38941 caatctgttt gacaatccga tagcgtccgg caaaaatctt gccgatttgg atcattcttc
    39001 atcctcctcg ttcatagaaa caagggcaac cgtaatgttg tctaaacctc ctgcattgtt
    39061 agcaaaacga acaagtgtct ccgttttatc tgctaaagga atatcactgg ttacaatatc
    39121 acgaatctca ctgcctgaaa tcatgttggt caagccgtca ctattgagca agagatagtc
    39181 acctgactca aggataactg tcccaaaatc aggctgaatt tcatcttttt gcccaataga
    39241 ctgggtgata atattttttt gcggatgagc ttctgcctct tctggtgtca attgaccagc
    39301 cttgagcaat tcattaacca aggaatgatc gctcgtcaac tgatggtatt cttctccacg
    39361 aatcaagccg atacgcgaat caccaatatg agcatagata gcctgattat caataatagc
    39421 aaggacttcc aaagtagttc ccatgcctct gtaagcttca tcctgaccaa gctggtgaat
    39481 cttttgattt tcaatttcta ggtaatgggc gaaccattca cgcacttcat tgactgtatc
    39541 gatctgggta tcaacccaag ctacacccag gtctgtgacc gccatttcac tagcgatatt
    39601 ccctgcacga tgacctccca tcccatcagc taaaataatc atggtacgtc cagctctatt
    39661 gacatagtgg ttgacatagt cttggttatt tgttcgtttc tgaccaacat ctgttaataa
    39721 tgaaatttcc atgtgtcagt tccttcctaa tccgatatct tgcgaaattg actgatgaag
    39781 aatccatcac ttccatacaa ttcaggtgta atgaggatac agccgtcttt catgatatcc
    39841 ttacattcat gttctagttt tacctgctcg aactcgggat gactctctaa aaaggcctta
    39901 acgacttgaa aattctcctc tgagacgata gtgcaggtgc tataagttat tataccacct
    39961 ttgcctagta tttgacaaac actacctaat atttctaact gaatttcctg caaggacgcg
    40021 aaatctgccg tttctttatt gtatttgata tctggttttc ggcgcaaaag accgattcct
    40081 gaacaaggag catccaccaa aatcttatca aaggaatcct ggtcaaaaaa ctcatgcacc
    40141 tttctggcat ccaatttttg agtttgaacc cgatcttcaa ctcccagacg ttgggcattt
    40201 tcttgaatta aatccaactt gtggtcgtac aagtccagag cagtaacctg acctgtcgta
    40261 agataagagg ctatatgggc tgttttccca cctggagccg cacaggcatc aagcactcgc
    40321 tcatcacctt gtaaatcaag cgtcggagca accagctgac tggactcgtc ttggatggta
    40381 atggctccat ccgcaaacaa attatgccct gcaaaatgcc cctgctcctt aaccagacca
    40441 gtggttgcta aaagggaatc attcgcctcc aacaaggctt ggatttcctc ttttcgactt
    40501 aggtctgtta cacgaatact ggctttgttt cgcactaaca ggctttcaaa gatggctttt
    40561 gctctctcct ctccgtattc ttccttgagt ttggcaacta gccaaactgg gagagaatag
    40621 gcaatggagt cacgcttgtt ttttcgcttg atgctagcaa tatctggcca gccttcacgc
    40681 aagatacggc gaaggagggc attgaccaat ttttcactgc cttttttacg aagtttggcc
    40741 aattccactg cttcattgac cacagcatga tctggaatct tgtccaaata gcggagttgg
    40801 taggcactca tgagaagaag gacatagagc cagctgtcta actggtctct gtcttcgata
    40861 aagtgggata ggtaccattc cagagtcagt ttacgggcta ccgttccata gaccagctcg
    40921 gtcactaagc ccttgtctgc tgccaaaagt tgactcccct ttagatgctt atttaaggcg
    40981 atatttgagt atgcttggtt cacaaaaaca tcctctagca ctgctagagc taaacttcta
    41041 gccgtttcta ctttagtcac caaatcgttc tcctacagtc aatgtacgtc caactccgtt
    41101 gaggaaggaa gcaatgtcca tcttaggctt accagctggc tgcacttgtt tgagggatag
    41161 agccccttca gccgttgcga caatcaattc tttcttgccg atagagagaa tctcacctgg
    41221 atttccctga ccttctactg gtagggcttc ataaatctta aagcggtcgc ccttaaggaa
    41281 agcatgggca acaggccagg ggttcattcc acgaatttgg ttaaagagtt gacgattggt
    41341 tttgttccag tccagttttt cttcctctgg ctttatattt ggagagaagg taacctgact
    41401 cgtatcctgc ggttcaggtt tgatatcacc agcaatatag gcaggcagag tgtccaaaag
    41461 caaatcacga ccaactagcg ccaatttttc aaacaaggtg ccaacattgt cctcatctgt
    41521 gatcggaatg ctgcgacgag aaatcatatc tcctgcatcc atttccttaa ccatttccat
    41581 gatggtcaca ccagcttcct catccccttg aatcaaggca taatggatag gcgcaccacc
    41641 acggtgtcta ggaaggaggg aggcatgaac gttgacagca aagtccatgc tatcaaggag
    41701 tttgcttggg agaaactgcc caaaagcagc agtcacaatt ccatctgctc ctagcttcat
    41761 aagttcttcc atctctggac ttccagataa tttttcaggt tggtagatag atagtcctgc
    41821 ttccttggca gcctgcttga ctggggtttc ttggataact tttttacgac caacagcacg
    41881 gtctggctgg gtcacaacgg ctagaatttc gtaacggtca tctgtcaaaa gtccttttaa
    41941 gactgttgct gaaaagtcgg gggtccccat aaagattagt tttgtcatat cttctccttc
    42001 ttataaaaat tgctgcggct catggtcaat gctgagacgg agctcactat tttcccgttc
    42061 ttgagtcaag gccaagacct ggttgagggt cggccccagc tcatcttcta aacggtattt
    42121 aattaaaatc tggtaatgat agaggttgtg ggtacgggca atcggttttg gcgttggccc
    42181 cagaatggga ctggtctctg acaagcctga ccgcaaaatg ttcatgactt cataggcacg
    42241 tttgaaaacc tcttcttctt tcttgtgaga aagggtaata ccaatcgtga aatagtaagg
    42301 tggatagccg agttgtcgtc tgattcccat ttcataggca taaaagcctt cgtaatcttg
    42361 atccttggca aatcgaatag catagtgctg cgaattgtag gactgtatca agacttgacc
    42421 tgctttttca gcccgacctg ctcgacctgc cacctgagtc aagagctgga aggttctctc
    42481 agaagaacgg aaatcaggca gattcaaggc cgtatccgca tttagaactc cgactagggt
    42541 aacattggga aaatccaaac cctttgcaat catctgagta ccaagtaaaa tatccgcttc
    42601 ccctcgccca aactggtcaa gcaaggcttg gtgactgcct ttctttcgag tcgtatccac
    42661 atccatcctc aaaatgcgag cttggggaaa gagttctgct agctcatcat aagccttctg
    42721 agttcccgtc ccatagtaac gaatactgcg gctcttacag ttaggacaga cctgaggaat
    42781 atccttcgag aaaccacaat aatggcagtt catagtcttg gtatccatat gcaaggtcag
    42841 agaaatatcg cagttgggac aagtatccac cgtcccacac tcccgacaca tgacaaagct
    42901 agaataacca cggcgattga gcatgagaac cacctgctct tttttaacca gacggtcttg
    42961 gatagcctct agcaaaggag gcgtaaagtt tgacgtctca ttttgtccga tatagtctcg
    43021 aaagtcaatc acttgaacct cagggattgt agccaaagga ttagcacgtt gggttagacg
    43081 taagtgttga tagacgcctt tgccagcacg tgcccggctc tctaagctcg gcgttgcaga
    43141 tccaagtacc agagttgctt gattatactg agcccgtaaa atagctacat ctctggcatg
    43201 gtaacgggga ttgctgtcct gcttataagc cacttcatgc tcttcatcaa taatcatgac
    43261 acccagattt ttcagaggag caaagatagc agatctggca ccaacaacaa cttgggcatc
    43321 gccacgctcc accttgcgcc attcatcata cttttcacca ttggataatc ctgagtgaag
    43381 aatggctacc ttgtccccaa aacgtgctat aaaacgctcg gtcatctgag gagtcaagga
    43441 aatctcaggt accagcaaaa tagctgtctt gcccttatcc agggcacctt ggataatctg
    43501 caagtaaacc tcggtcttcc cacttcctgt aatcccttga agtagaaagg gaggttgaga
    43561 actgccaata gaactcacaa ccgcatcacg cgcctgtctt tgttctggat ttaactccaa
    43621 aggtctactt gcttcaattc cttcaaaata agcagccgag cgttgaactt ccttttggac
    43681 tatggtaaca gcaccttgat ccacaaagaa gttgacttgc tctcgcgagt aggactctaa
    43741 caagctagcc aaggaagcgc tctctggatg agacagcaga taatctctca gttccaactt
    43801 tttcttggca cgtgtagaaa tctcaacacc ttctaattga gcatggtcaa cctcatacca
    43861 agactgggtc ttgaccttct tttgatcgac tgcctgatat tccagaccaa gcaggccttt
    43921 tctagtcaaa cgcatcattt cagcttgctt ggcaaggtct agtgaagaaa aggctagcga
    43981 atcttctgaa ccaaacaggc gcactcgttc ttcctgactc aagccttcca gaggatagag
    44041 aatcttgtca tagctagaat tcagaaatcc tggaagcatg gccttgagga tagaaatttt
    44101 gtaggagaag acagatttgc gtaactcctc agccagccag agttgttctg gcgtgagaac
    44161 aggagaaaaa tccagcacct ctgcaatatc ttttaaatct tgctccatct cttctccatc
    44221 tgattgggac tccaaaccaa gaacaatccc ttgaatcagg cgattcccct taccaaaagg
    44281 cacatgaacc cgcatcccaa cttccagcat tccctcaaat tcctccggaa tcctgtaact
    44341 atagggctgg tccgtctgca tcaagggcac atctacgata atcttagcta gggccatcgt
    44401 ctcacctcct ccttgtcagt acattcttgc aatagaaaaa ataagattga gtccccccaa
    44461 ccttaaattt tttcaccatc ttctttttct ttagcaattt gctctttgat tttcttttct
    44521 tcttcttctt tgcggcgttt ttcttcttcg atacggcgac gcactgcttc acgttttcct
    44581 tctggatctg ggtgaattgt aacgtttcct gattcgattt cttctaaagc gcgaagagtt
    44641 gatttttcag acttaaaacc ttgagttgct ggggcacctg cttccaattc gtgggcacgt
    44701 tttgcttcca agattacgag tgaatatttt gaaggaacct tgtcgagcaa ggtatcaata
    44761 gagggtttta acatcatttg cttgtaccta ttttctaaat tttatcgggt agttggagat
    44821 tttggtaaca tctcctgata gtgaccaatg acacgatcca cacagaagtg ttctgcttca
    44881 atcacacatt tgacacgttc agcagctagg ggtacctgat cgttgacaat cgcataatca
    44941 tactcacgca tgagggcaat ttcttccttg gccttttcga ttcgttgggc aatcacttct
    45001 gcactatctg ttccacgacc taccaagcga tcttgcaatt catccaaatc tggtggtgtc
    45061 aggaagataa agacagcatc tggaaccttt ttcttgacct gaagagcacc ctgaacttca
    45121 atttcaagga aaacatcgat tcccttgtcc aaggtttcat tgacataggt cagaggagtt
    45181 ccatagtagt tgccgacata ttctgcgtat tccaacatct gtccttgacg aatcagctct
    45241 tcaaattctt cacgagtacg gaagaaatag tcaacaccgt ccacttctcc aggacgttgt
    45301 gcgcgtgtcg tcatcgatac agaatattga aattggtttt cagaactctc aaaaatctct
    45361 cttctaaccg ttccttttcc aacccctgaa ggaccagaaa aaacgattag taagcctcgg
    45421 tctgccattg tgtctccttt tagtcaatct gtgaaataac atttctctag aataatggca
    45481 aaaagccaga ttatccttta cagtctttct atctagtgta acaaaaaagc agtaattttt
    45541 caactgctct ttcttattta tttagcataa tctactgcac gaagctcgcg aatcacggtt
    45601 accttgatat ttcctggata atcgagattg ttttcaattt tcttacgaac tttgtgagcc
    45661 aagattgtga ctttgtcgtc cttgattttt cctggattga ccatgatacg aatttcacgt
    45721 cctgcttgaa gggcaaagct agtttgcact ccttcaaagc cgttagcaat ttcttccaaa
    45781 tcatggagac gcttgatgta gctttcaaga gactcactac gagcacctgg acgggctgcg
    45841 ctcaaggcat ctgctgcagc gacgataact gctatcacgc tctcagcttc aacatctccg
    45901 tggtgactag caatcgtatt caccacaact gggggttcct tgtacttacg ggccaattcc
    45961 ataccgattt caacgtggct accttcaacc tcatggtcaa tggctttccc gatatcgtga
    46021 aggaatccag cacgacgggc aagagccgca ttttcaccaa gttcgctcgc catgatacca
    46081 gccaacttag caacctcaat cgaatggcgc aaaacatttt gtccatatga agtacggaac
    46141 tgcaaacgtc ccataatctt catcaagtct ggatgaaggt ttggcgcacc aatttcatag
    46201 gcagcagcct caccgtattc acgaatctta ttgtcaatct cttgacggtt tttctcaacc
    46261 aactcttcga tacgagctgg atgtatacga ccatctttga gcaacatttc catagtcata
    46321 cgggcaatct cacgacgaat cggatcaaat cctgacaagg tcaccacttc tggtgtatcg
    46381 tcgataatca catcgacccc tgtcaaactt tcaaaggtac gaatgttacg accttcacga
    46441 ccaataatgc gtcccttcat agtatcgtct ggcagatgaa ctgttgagtt tgttgactcc
    46501 gctacatatt caccagcgat acgttgcata gcttgaacca agatgtcctt ggccattttg
    46561 tcagaacgtt ccttgacctc ttgctcagct tcgcgaatgc gactggcaat ctccctggtc
    46621 aagttttcct ctgtctgagc caagataata tctcgtgctt ctgcctgaga cagagcacca
    46681 atacgctcta gttctgcttc tttttgtctt tcgacttcct ctaattgctc ttcacgcgca
    46741 tcaaggtttt tcgctctatc agaaatactt tgttcttttt gttcaagtgt ttgttcttta
    46801 ctcgtcaaat tgtcgtcctt acggtcaagg ctagtagctc tctctgtcaa acgactttcg
    46861 atttgtttga gttcttgacg ttctgatttg aattcagcgt ccacttcttc acggtatttt
    46921 ctggcttctt ctttggcctc caatagtgct tcttttttaa gagacttgct ttcacgtttg
    46981 gcttcattaa caagtaaatc cgcttcacgc tcagcttgtc cacgtaaatt agttgcttct
    47041 tgttcagcat ttaaaagcat caactctgca gcttcctgag atgatttcat cttagctgag
    47101 atgctgacat atccaatgac taaaccaatg atgacggcaa aaacagcaat cgcaagcgac
    47161 atgatttcca tgtttttacc tcattttatt gttattccga atgacataca ttcttttaca
    47221 ttctaccata aaaaaagaat ttaaacaaac cttaaatgga tatcgctaac atccgcatta
    47281 tcactatcat agttatcatt tacagatata aagcgaatac ctttttcagg aaatatcttt
    47341 tgtaagtact ttcctgactc gatataatct ctgccgaaac gagataaatc ttttaccata
    47401 atgatagaaa actttccttt attcaggtca tcaatcatat tcttaaaatt tggtcgctca
    47461 aaattagaac cactatatcc atcatctaca tattcatagg ataattcaat agatttctct
    47521 tctacctcca aaaagcaaaa aggataaatt tcccctacac tttaatagtg aaaatttatc
    47581 cctcttggta agctctttta ttaatttttt tgataaagaa aacgcacatt t
//
LOCUS       DAVLBE010000011        41639 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.011, whole genome shotgun sequence.
ACCESSION   DAVLBE010000011 DAVLBE010000000
VERSION     DAVLBE010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 41639)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41639)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41639
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.011"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(89..286)
                     /locus_tag="VXB91_000644"
     CDS             complement(89..286)
                     /locus_tag="VXB91_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEV0470140.1"
                     /translation="MTLNEYILQYRLKQAIDKMAESPNSPLSAISDQVGFSDYKYFAK
                     VFKKYLHISPKKLKSLGRIVK"
     gene            complement(361..1137)
                     /locus_tag="VXB91_000645"
     CDS             complement(361..1137)
                     /locus_tag="VXB91_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HEV0470141.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGINALHPEDLIDYQKVFLNHHINCYF"
     gene            1259..2005
                     /locus_tag="VXB91_000646"
     CDS             1259..2005
                     /locus_tag="VXB91_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV0470142.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     HQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNIATLENAGIMVKVVS"
     gene            2018..2998
                     /locus_tag="VXB91_000647"
     CDS             2018..2998
                     /locus_tag="VXB91_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HEV0470143.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNAGIVKIEIENFDTNMFKLENYVKEKYGLESLEIIPNEFDDNPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
     gene            3193..3513
                     /locus_tag="VXB91_000648"
     CDS             3193..3513
                     /locus_tag="VXB91_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV0470144.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
     gene            3559..3867
                     /locus_tag="VXB91_000649"
     CDS             3559..3867
                     /locus_tag="VXB91_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0470145.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQASGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            3884..5182
                     /locus_tag="VXB91_000650"
     CDS             3884..5182
                     /locus_tag="VXB91_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV0470146.1"
                     /translation="MAKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLLSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSWYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASGNLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQALGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVITQLVILAMSTLVYFPFFKVQDRLAYQNEIKQS"
     gene            5333..7771
                     /locus_tag="VXB91_000651"
     CDS             5333..7771
                     /locus_tag="VXB91_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HEV0470147.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMTIYIEEESMIGGNQASSNKDAPIFPEYTLE
                     FVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKAALDLTDPASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPATTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            7790..8458
                     /locus_tag="VXB91_000652"
     CDS             7790..8458
                     /locus_tag="VXB91_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEV0470148.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHEIRRQAGDDIFIKVPVTPAGLRAIKVLK
                     KEGYHITATAIYTVIQGLLAIEAGADYLAPYYNRMENLNIDSNSVIRQLVLAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVTQN
                     SRSI"
     gene            8476..9564
                     /locus_tag="VXB91_000653"
     CDS             8476..9564
                     /locus_tag="VXB91_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HEV0470149.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNYPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTLKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
     gene            10019..12520
                     /locus_tag="VXB91_000654"
     CDS             10019..12520
                     /locus_tag="VXB91_000654"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HEV0470150.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQ
                     AEAVADYKHQASLKSDLVRTDLAKEKTGVWTGAYAINPVNGKEMPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDA
                     IAKIVACLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPETELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVEKRDGSFFHIETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITSKEILAENNGALD
                     KAYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDKLYVDYAKGFIQLIAPFAPHL
                     AEELWQTVAETGESISYVAWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDLSREEL
                     QEIALADEKVKAEIDGKEIVKVISVPNKLVNIVVK"
     gene            12714..13409
                     /locus_tag="VXB91_000655"
     CDS             12714..13409
                     /locus_tag="VXB91_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0470151.1"
                     /translation="MPVNEYGQMIGESMEGYTPGELPSIDFLEGRYARIEALSVEKHA
                     EDLLAVYGPDTPREMWTYLFQEPVADMGELVSLLHQMLARKDRFYYAIIDKATGKALG
                     SFSLMRIDQNNRVIEVGAVTFSPELRGTRIGTEAQYLLARYVFEELNYRRYEWKCDAL
                     NLPSRRAAERLSFIYEGTFRQAVVYKGRTRDTDWLSMIDKDWPQVKDRLETWLRPENF
                     DKNGQQYKSLREL"
     gene            13421..13837
                     /locus_tag="VXB91_000656"
     CDS             13421..13837
                     /locus_tag="VXB91_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0470152.1"
                     /translation="MITIKKQEIVKLEDVLHLYQAVGWTNYTHQPEMLEQALSHSLVI
                     YLALDGDAVVGLIRLVGDGFSSVLVQDLIVLPIYQRQGIGSALMKEALEDYKDAYQVQ
                     LVTEETERTLGFYRSMGFEILSTYNCIGMTWMNRKK"
     gene            complement(14652..14744)
                     /locus_tag="VXB91_000657"
     CDS             complement(14652..14744)
                     /locus_tag="VXB91_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HEV0470153.1"
                     /translation="MMELVLKTIIGPIVVGVVLRIVDKWLNKDK"
     gene            14905..15876
                     /gene="ruvB"
                     /locus_tag="VXB91_000658"
     CDS             14905..15876
                     /gene="ruvB"
                     /locus_tag="VXB91_000658"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HEV0470154.1"
                     /translation="MGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEAAKMRDEALD
                     HVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNELEPGDVLFIDE
                     IHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTRAGMLSNPLR
                     ARFGITGHMEYYAHAGLTEIVERTADIFEMEITHEAASELALRSRGTPRIANRLLKRV
                     RDFAQIMGNGVIDDIITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGGPVGLGTLSV
                     NIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            15857..16429
                     /locus_tag="VXB91_000659"
     CDS             15857..16429
                     /locus_tag="VXB91_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001098890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HEV0470155.1"
                     /translation="MNTVKNKQEILEAFRENPDMMAILTIIRDLGLKDSWLAAGSVRN
                     FIWNLLSDKSPFDHETDIDVIFFDPDFSYEETLLLEKKLREDFPQYQWELKNQVYMHQ
                     HSPHTASYTSSRDAMSKYPERCTTVGLRLNEESDFELYAPYGLEDILNFQVRPTPHFL
                     ENEDRMELYQTRLSKKNWQEKWKNLIFKNT"
     gene            16660..17418
                     /locus_tag="VXB91_000660"
     CDS             16660..17418
                     /locus_tag="VXB91_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HEV0470156.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV"
     gene            17427..18230
                     /locus_tag="VXB91_000661"
     CDS             17427..18230
                     /locus_tag="VXB91_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HEV0470157.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLAMHE
                     LLKIRGLATMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            18252..19511
                     /gene="rseP"
                     /locus_tag="VXB91_000662"
     CDS             18252..19511
                     /gene="rseP"
                     /locus_tag="VXB91_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HEV0470158.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTALPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETAQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPEDSQG
                     RYLLGVQPGVKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRHKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            19524..21377
                     /locus_tag="VXB91_000663"
     CDS             19524..21377
                     /locus_tag="VXB91_000663"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HEV0470159.1"
                     /translation="MKQSKMPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPTLLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTAEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            21477..22856
                     /gene="bglA"
                     /locus_tag="VXB91_000664"
     CDS             21477..22856
                     /gene="bglA"
                     /locus_tag="VXB91_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEV0470160.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTVFRTSIQWSRIFPQGCGKVNPQGVDFYRK
                     VFEAIKAKGIRLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIRDNTVDFLGVNYYQPLRVMAPRFAKHPDSPLLPEHFYEPYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KELSDNNGF"
     gene            23048..24856
                     /gene="glmS"
                     /locus_tag="VXB91_000665"
     CDS             23048..24856
                     /gene="glmS"
                     /locus_tag="VXB91_000665"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HEV0470161.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGADNHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYLEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEDGLSVLEAFKKALHIIRGSYAFAL
                     IDSENPDVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNSRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDDAGQ
                     VVIDPAIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQAFDLVHELSIVAQSIESTLSEKET
                     IEAKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLALLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGLDVDKPRNLAKSVTVE"
     gene            24975..26024
                     /locus_tag="VXB91_000666"
     CDS             24975..26024
                     /locus_tag="VXB91_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HEV0470162.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKVGLD
                     VYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDAL
                     SNGRSEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLDLLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIGGNPRYFKKLIQAYRE
                     IGSEAGHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLEQVGPNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHLPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
     gene            complement(26124..29921)
                     /gene="spuA"
                     /locus_tag="VXB91_000667"
     CDS             complement(26124..29921)
                     /gene="spuA"
                     /locus_tag="VXB91_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HEV0470163.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNESDISSPRNANASLEKTEEKPATEPT
                     TSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQGLWTWDDVEKPSENWPNGALSF
                     KDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNLTGDKSVEKLVPKMNEAWLDQDY
                     KVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVKNPSSAQWPDGTDFTATGKYGRY
                     IDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFTDLKNHSQIFLKDDDESIYTNPY
                     YVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKHSNITNHLGNKVTITDVAIDEAG
                     KKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWHLKDETYSYDGKLGADLKEEGKQVDLT
                     LWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTWKQTLDSTNKLGITDFTGYYYQY
                     QIERQGKTVLALDPYAKSLAAWNSDDAKIDDTHKVAKAAFVDPAKLGPQDLTYGKIHN
                     FKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEAFIEKLDYLKDLGVTHIQLLPVL
                     SYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSLTGMYSSDPKNPEKRIAEFKNLI
                     NEIHKRGMGAILDVVYNHTAKVDIFEDLEPNYYHFMDADGTPRTSFGGGRLGTTHHMT
                     KRLLVDSIKYLVDTYKVDGFRFDMMGDHDAASIEEAYKAARALNPNLIMLGEGWRTYA
                     GDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGYPNEGQPAFITGGKRDVNTIFKN
                     LIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSIKKDPSKAENYAEIHRRLRLGNL
                     MVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDKVPNKSHLLRDKDGNPFDYPYFI
                     HDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKGLIALRQSTDAFRLKSLQDIKDR
                     VHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVNADEKAREFNLGTAFAHLRNAEV
                     LADENQAGSVKIANPKGLEWTEKGLKLNALTATVLRVSQNGTSHESTAEEKPDSTPSK
                     PEHQNEASHPAHQDPAPEARPDSTKPDAKVADAENKPSQATADSQAEQPAQEAQEASV
                     KEAVRNESVENSSKENIPATPDKQAELPNTGIKNENKLLFAGISLLALLGLGFLLKNK
                     KEN"
     gene            30338..30751
                     /gene="rpsL"
                     /locus_tag="VXB91_000668"
     CDS             30338..30751
                     /gene="rpsL"
                     /locus_tag="VXB91_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HEV0470164.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            30771..31241
                     /gene="rpsG"
                     /locus_tag="VXB91_000669"
     CDS             30771..31241
                     /gene="rpsG"
                     /locus_tag="VXB91_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HEV0470165.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            31665..33746
                     /gene="fusA"
                     /locus_tag="VXB91_000670"
     CDS             31665..33746
                     /gene="fusA"
                     /locus_tag="VXB91_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HEV0470166.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLIEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEETRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIDTVYSGDIAAAVGLKDTTTGDSLTDEK
                     AKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLSLKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            33850..38241
                     /locus_tag="VXB91_000671"
     CDS             33850..38241
                     /locus_tag="VXB91_000671"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HEV0470167.1"
                     /translation="MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKARSQEFSNQLLQSYYREAFSEGP
                     CASQGFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VEKNDVLTQEQEEAFHAENEQIVQAANEEALRAMEQLEQMAPPPAEEKPVFDFQAKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDLQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGIEANIVEDRVPIVYNEVEMDLSEATYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNAAFDVGFMNANYERHGLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVD
                     AAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFEPVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNKIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEVIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYRSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            38343..38606
                     /locus_tag="VXB91_000672"
     CDS             38343..38606
                     /locus_tag="VXB91_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HEV0470168.1"
                     /translation="MSKMSISIRLDSEVKEQAQQVFSNLGMDMTTAINIFLRQAIQYQ
                     GLPFDVRLDENRKLLQALTDLDQNRNMSQSFESVSDLMEDLRA"
     gene            38599..38877
                     /locus_tag="VXB91_000673"
     CDS             38599..38877
                     /locus_tag="VXB91_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HEV0470169.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPARY
                     RDHSLTASKHFQGVRECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            38898..39050
                     /locus_tag="VXB91_000674"
     CDS             38898..39050
                     /locus_tag="VXB91_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0470170.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGIF
                     SALKEK"
     gene            39072..40313
                     /locus_tag="VXB91_000675"
     CDS             39072..40313
                     /locus_tag="VXB91_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HEV0470171.1"
                     /translation="MVLPNFKENLEKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDFLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEEFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVTFKDGQIVDITAEKGDQVMKDLVFENAGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSVVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAN"
     gene            40323..40553
                     /locus_tag="VXB91_000676"
     CDS             40323..40553
                     /locus_tag="VXB91_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEV0470172.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAILGAMIVLAIFWRRGS"
     gene            40911..41633
                     /locus_tag="VXB91_000677"
     CDS             40911..41633
                     /locus_tag="VXB91_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEV0470173.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRL
                     DIDTHGLLLLTNNGQLAHVLLSPKRHVDKTYQAQVKGIMTQEDVETFIKGIPLKDFTC
                     QPARLEILSTDAEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILRANII"
BASE COUNT        12292 a         7410 c         9472 g        12465 t
ORIGIN      
        1 aattaatttg actttcctga tagagatgtt cacatcttat ttcaattcac tatattagag
       61 taaaattctc tacaaaaaga agaatagcct atttgactat tcttccgagt gatttcaatt
      121 tctttgggga aatatggaga tactttttaa atactttggc aaaatattta tagtctgaaa
      181 atccaacttg gtcagagata gcgcttaaag gggagttggg agattcagcc atcttatcta
      241 tagcttgttt caggcgatat tgtaagatat attcatttag agtcatgggg aagtcttctt
      301 tgataacctt atatagatgc ttgttatctg caaatagcta gagcatttca aggaaataaa
      361 ctagaaataa caattaatat ggtggttcag aaataccttt tgataatcaa taagatcttc
      421 aggatgaagt gcgttgattc catccatttc atatttccga tttaataaac gatatttgtt
      481 ttcaccaaat tgatgaaaag ggagtagttg aacttggtcg atatttaatg agttaaatag
      541 agtagcgaat ttttctgcat cctctaaact attgttaaaa ttaggaataa ctgggattct
      601 taaaacgata gttttatttt gagaaaaagc ataatgaatg tttttaataa tcatttgatt
      661 aaaaacccca gtcacttttt tatgttttat agaattataa tgttttaggt ctgtgtagat
      721 aaaatccaca tattgaatta aatcaataaa tttttcatga tcaacaaagg cagtagtttc
      781 aatggcagtg tgtatgtgat gttctttagc tgattttaag atggctttag caaattcaaa
      841 ctgagcaaat atttcacctc ctgataaagt taaacctcca ccggattctt cgtaaaattc
      901 tttgtctttt aatacctctg taataatttc ttctacagtc ttttcttcac cgactaaggt
      961 gaatttctct cgttgagcat ctttcatttt ttcaggtttc attctttgag attcaggatt
     1021 agaacaccat ggacagcgca gaggacatcc ttttaaaaaa acagttgtac gaatacccgg
     1081 gccgtcatga attgaaaagt gttgaatatt aaaaataatt cctttagata tttccataag
     1141 agttcctcct cttcataagt ctatcctatc acaaaaacga aagaaaaaca attacgaacg
     1201 aaagtttaat ttgttgtttt ttgcttttta ttttggtaga ataaaacgga ggtgtaaaat
     1261 gaaaagattg gaacaaatta ttaaattagt atcagaatat gaaaagatcg acgttaatac
     1321 attatcggaa aaattaaatg tatcgaaagt aacgattaga aaagatttag ataaattaga
     1381 gtcaaaaggt ttattacaca gagagcatgg atatgctgta ttaaatagtg gagatgactt
     1441 aaatgtacgt ttgtcaatta actatgaaat taagagaaaa attgttcagg aagcagtaaa
     1501 attggtgtca gataatgaaa caataatgat agaatctgga tcgacctgtg ctttacttgc
     1561 tgaggaaatt tgcaagcaaa aaagaaatgt tacgattgta acaaattcat tttttatagc
     1621 aaattttgtg agagcttatg attcatgtcg tattattgtt cttggtggag agtttcagaa
     1681 ggattcacag gttactgtgg gacctttatt aaaagaaatg atacagactt ttcatgtgca
     1741 tcaagctttt gttgggacag atggttacga taaagagatg ggctttacag gaaaagattt
     1801 aatgcgcagt gaggtagttc aatatatttc agcagcgtcg gataaagtca ttgtactaac
     1861 tgactcaagt aaatttgata aaaggggtac agtaagaaga tttgctttaa gtcaagtcta
     1921 tgaagtaata acagacgaaa aactttctaa acaaaatata gctacattag aaaatgctgg
     1981 gataatggtt aaggtagttt cgtaagaggt taaatgtatg aatcaagata ggaataaact
     2041 gctctctaaa attgcttatc tgtattatat tgaaaactta aatcagtcac aaatagcagc
     2101 aaaattagga atttatagaa cctctattag tagaatgtta acagaagcaa ggaatgcagg
     2161 aattgttaaa attgaaatag agaattttga taccaatatg tttaagttgg aaaattatgt
     2221 aaaagaaaaa tatggtctgg aaagtttaga aattattcca aatgaatttg atgataatcc
     2281 aacaatttta tctgaaagaa tttctcaagt tgcagcaggt gtccttagga atctaattga
     2341 tgataatatg aaaattggct tttcttgggg gaaaagttta agtaatttag tagatttaat
     2401 tcacagtaaa agtgtccgaa atgttcactt ctatcctcta gcaggtggtc ctagtcacat
     2461 acacgctaaa taccatgtga atacactgat ttatgaaatg tctagaaaat ttcatggaga
     2521 gtgtacattt atgaatgcaa cgattgtgca agaaaataaa ttgttagcag atggtatttt
     2581 gcaatcaaga tattttgaaa atttgaaaaa tagttggaaa gatttagata tagctgtagt
     2641 cggaattggt gattttagca ataaaggaaa gcatcaatgg ttagacatgc ttacagagga
     2701 tgactttaaa gaattgacca aagttaaaac tgtaggagaa atttgttgtc gattttttga
     2761 ttcaaaaggt aaagaagtct atgaaaactt acaggaaaga acgatagcaa tctctttgga
     2821 agatttaaaa aatattcctc aaagtttagc tgttgcttac ggtgatacga aagtatcttc
     2881 gattctttct gtcttgcgtg ctaatttagt aaatcatttg attacagaca aaaatacaat
     2941 tttaaaagtt ttggaagaag atggggattt gacttttaga gagattctag gtgagtgaaa
     3001 atgatagact gatcagttta tcgttttttc tttttagtcg attgcacatt tgtgctcata
     3061 taaacaaaaa tagtttatct gttgtttttg gattgacaac tttattatgt agttgtattc
     3121 tatagttaca aaagaaaatt ttaaaatttc aaatgaaaaa agctttttac atagtgaaat
     3181 gaggaggaat ttatggaaat tattgttcca gatcaaatta tcatgggttt aattttatat
     3241 gctggtgatg cgaaacaaca tatttataaa gcgttagatt acataaaaaa tggtacatgt
     3301 gaacggtgtg aagaagaaat ccagttagct gatgccgcct tattagaagc ccataatcta
     3361 caaacaaaat tcttggcaca agaagcgtct ggtacaaaga cagaaattac agctctcttt
     3421 gttcattcac aagatcatct catgactagt atgacggaga ttaatttaat caaagaaatt
     3481 attagtttga gaaaagaact tcataaaaaa taatactaga gtattatcat tgttattaac
     3541 atagaggagg aaaacataat ggtgaagatt ggtttgtttt gtgcagcagg tttttctact
     3601 ggtatgcttg taaataatat gaaaattgca gcgcaagcta gtggagttga ggcagaaata
     3661 gaggcgtttt ctcagtctaa attagcggat tatgcgccaa atatagatgt tgcactattg
     3721 ggtccacaag ttgcttatac attagataaa tcaaaagaaa tttgtgataa gtgtgatgtt
     3781 ccgatagctg ttattccgat gatggactat ggtatgttag atggaaaaaa agtattagat
     3841 ttggccctat ctttgattag tgggtaagaa aaggagattt attatggcaa agatggatgt
     3901 tcagaaaatc attgcaccga tgatgaagtt tgtgaatatg cgtggcatta tagctctaaa
     3961 agatgggatg ttagcaattt tgccattgac agtagttggt agtttattct tgattatggg
     4021 acaattgccg ttcgaaggat taaataagag cattgctagt gtttttggag ctaattggac
     4081 agagccgttt atgcaagtat attcaggaac ttttgctatt atgggtctaa tttcttgttt
     4141 ttcaattgcc tattcttatg ctaagaatag cggagtagag gctttaccag ctggagttct
     4201 atctgtatct gcattcttta ttttgctaag atcatcttat atccctaaac aaggtgaggc
     4261 aattggggat gctattagta aagtttggtt tggaggtcaa ggaattatcg gtgctatcat
     4321 tataggtttg gtagtaggaa gtatttatac cttctttata aagagaaaaa ttgttattaa
     4381 gatgccagaa caagttccac aagctattgc caaacagttt gaagcaatga ttccagcatt
     4441 tgtaattttc ttactttcta tgattgtata tattttagcg aagtcattga ctaatggcgg
     4501 aacattcata gaaatgattt attctgctat tcaagttcca ttgcaaggtt taactggatc
     4561 ttggtatggt gcaattggaa ttgcattctt tatatcattt ttgtggtggt ttggtgttca
     4621 tggacaatcg gtagtaaatg gagtagtgac agctctgctt ttatctaatc ttgatgctaa
     4681 taaagctatg ttagcctctg gtaatctatc attagaaaat ggtgcacata ttgttactca
     4741 acaattttta gattcatttt taattctatc aggttcaggg attacgtttg gtcttgtagt
     4801 tgccatgctt tttgcagcaa aatcaaaaca ataccaagcc ttaggaaaag ttgccgcttt
     4861 tccagcaata tttaacgtaa atgagccagt tgtatttgga tttccgattg tcatgaatcc
     4921 agttatgttt gtacctttca ttcttgttcc tgtacttgca gctgtgatag tatatggagc
     4981 tattgcaaca ggtttcatgc agccattctc aggggtaaca ttgccttgga gtacaccagc
     5041 tattttatca ggatttttgg tgggtggatg gcaaggagtt attactcagc tggtgatatt
     5101 agcgatgtct acattggttt attttccatt ctttaaagta caggatcgtt tagcttacca
     5161 aaatgaaatc aaacaatctt agaggtattt gtgtgttact gttaaactca cacatttgtg
     5221 ctaaaaatta gagagttaaa atttttctag ttaaaagctt gaaaatttct ataaaaatcg
     5281 gtattatatt ttcgaaagaa ataaaaatat tttcgaaaga aaggtggtta cgatggtaaa
     5341 tacagaagta gcaagaacaa caatcaagac agaatatttt ggcagcctta ctgaaaggat
     5401 gaacaaatat cgagaagatg ttttaaataa aaaaccttat attgatgctg agagagcagt
     5461 tctagcaaca cgcgcctatg aacgatacaa ggaacaacct aatgtcctaa aacgtgcata
     5521 tatgctgaaa gaaattttgg aaaatatgac tatctatatt gaagaagaat ctatgattgg
     5581 gggaaatcaa gcttcttcca ataaagatgc tcctattttt ccggaatata cgctagaatt
     5641 tgttctcaat gagttggatc tttttgaaaa gcgtgatgga gatgttttct atattacaga
     5701 agaaacaaaa gaacaactta gaagtattgc tccgttttgg gaaaataata atttacgtgc
     5761 tagagctggt gccttattac ctgaagaagt gtctgtttat atggaaacag gattcttcgg
     5821 tatggaaggt aagatgaatt ctggagatgc tcacctagca gttaactatc agaaactttt
     5881 gcaatttggc ttaagaggtt ttgaagagcg ggctcgtaaa gcaaaagcag ctctagattt
     5941 aacagatcca gcaagtattg ataaatatca tttttacgac tctatattta tcgtaatcga
     6001 tgctattaaa gtatatgcaa agcgctttgt tgctcttgct aaaagtttag ccgaaaatgc
     6061 aaatcctaaa cgtaagaaag aattacttga gattgcagat atttgctcta gagtcccata
     6121 tgaaccggca actacttttg cagaagctat tcaatcagtt tggtttattc aatgtatttt
     6181 acaaattgaa tctaatggcc actctctttc atatggccgt tttgatcaat atatgtatcc
     6241 atatatgaag gctgatttag aaagtggtaa agaaacagaa gatagcattg ttgaacgtct
     6301 gacaaatctt tggattaaga caattacaat taataaggtt cgcagtcaat cacatacatt
     6361 ttcttcagca ggaagtcctt tatatcaaaa tgttacaatt ggtggacaga ctcgagataa
     6421 gaaggatgct gttaacccat tatcttattt ggtattaaaa tcagttgcac aaacccatct
     6481 accgcaacct aatctaactg tacgttacca tgcaggttta gatgctcgtt tcatgaatga
     6541 gtgtattgaa gtgatgaaac ttggttttgg tatgcctgca tttaataatg atgagattat
     6601 tattccttct tttattgcaa aaggagtatt ggaagatgat gcttatgatt acagtgccat
     6661 tggatgtgtt gaaacggcag ttccagggaa atggggctat cgttgcacag gtatgagtta
     6721 tatgaacttc cctaaggttc tacttatcac gatgaatgat ggaattgatc cggcttcggg
     6781 taaacggttt gcaccaagct ttggtcattt taaggatatg aagaactttt ctgaattaga
     6841 aaatgcttgg gataaaacac taagatattt gacacgaatg agtgttattg ttgaaaattc
     6901 tattgattta tcattggaac gagaagttcc tgatattcta tgttcagcat tgactgatga
     6961 ttgtattggt cgtggaaaac accttaaaga aggtggagca gtatatgatt atatatcagg
     7021 attgcaagtt ggaattgcaa atttgtcgga ttcattagct gcaattaaaa aattggtgtt
     7081 tgaggaagaa cgtataagcc caagtcagct ttggcatgca ttggaaacag attatgccgg
     7141 agaagaaggt aaggtcattc aagaaatgtt gattcatgat gcacctaagt atggtaatga
     7201 tgatgattat gctgacaaat tggttactgc tgcttatgac atttatgttg atgaaattgc
     7261 taaatatcct aatacacgtt atggaagagg gcctattgga ggaattcgtt attcaggaac
     7321 atcttctata tcagccaacg tagggcaggg acgtggaaca ttagcaactc cagatggacg
     7381 caacgcgggt acaccgttag cagagggttg ttcaccatca cataatatgg atcaacacgg
     7441 ccctacatct gttttaaaat ctgtttcaaa attaccaaca gatgaaatcg taggtggggt
     7501 tctcttaaat cagaaagtaa atcctcaaac gttagccaaa gaagaagata aattaaaact
     7561 aattgctttg ttacgaacat tctttaatcg tttacatggg taccatattc aatacaatgt
     7621 tgtttccaga gagacgttga ttgacgctca gaaacatcct gaaaaacaca gagacttaat
     7681 tgttcgtgtt gcaggatact ctgcattctt caatgttctt tctaaggcaa cccaagatga
     7741 cattatagga cgtactgagc atactttgta aaataaagag gttcttttta tggaatttat
     7801 gcttgacaca ttaaatttag atgagattaa aaagtggtct gaaattttgc cgctagctgg
     7861 ggtaacttca aatcccacta ttgcaaaaag agagggttct attaattttt ttgaacgaat
     7921 caaagatgta agagaattga ttggctccac accctctatt catgttcagg tgatttctca
     7981 agattttgaa ggcatcttaa aggatgctca tgaaattcga agacaagcag gagatgatat
     8041 atttatcaaa gtacctgtta ctccagctgg attacgtgca ataaaggtgc taaaaaaaga
     8101 gggctaccat atcactgcaa cagctattta tacagttatt cagggattat tagctatcga
     8161 agcaggagcg gattacctag ctccatatta taatagaatg gaaaatctga acattgattc
     8221 aaattctgtc attcgtcaat tagttcttgc tattgataga cagaactctc ctagtaagat
     8281 tttggctgca tcctttaaaa atgtagcaca agtaaataat gctttagctg caggtgcgca
     8341 tgctgttaca gcaggagcag atgtttttga atcagctttc gccatgccat ctatccaaaa
     8401 ggcggttgat gatttttctg acgattggtt tgttactcaa aatagtcgtt ccatttagat
     8461 agagaggaaa tacatatgag aatttttgct agtccttcta gatatattca gggggaaaat
     8521 gccttgtttg aaaatgccaa atcaattttg gatttgggaa attaccctat tctattatgc
     8581 gatcagttgg tttatgatat tgttggaaaa cgatttgaag attatctaca taggtatggt
     8641 ttccatattg ttctggcgct atttaatggt gaagcttctg acaatgaaat caatcgagtt
     8701 gttgccttgg ctgagaaaga aaattgtgat agtattatcg gtcttggtgg gggaaagacg
     8761 attgatagcg caaaagctat tgcagatttg attgaaaagc ctgttattat tgctccaaca
     8821 attgcatcga ccgacgcacc tgtatctgct ttatctgtta tttatacaga tgaaggtgca
     8881 tttgatcatt atctatttta ttctaaaaat ccagatttag ttttggttga tacaaaagtt
     8941 atttcacaag cccctaagcg tttattagcg tctggtattg cagatggttt agcaacttgg
     9001 gttgaggcgc gtgcggttat gcaggcaaat ggaaaaacta tgttgggaca acagcaaaca
     9061 ttggctggag ttgcaattgc gaagaaatgt gaagaaacgc tgtttgcaga tggtttacag
     9121 gctatggcag cttgtgaagc taaagtggtg acaccagcat tagaaaatat tgttgaagct
     9181 aatactttat tgagtggtct aggttttgaa agtggaggat tagctgcggc gcatgcaatt
     9241 cataatggtt ttactgcatt gacaggtgac attcatcatt taacacatgg tgaaaaagta
     9301 gcttatggaa ctttagtaca actattattg gaaaatagac ctaaagaaga acttgataag
     9361 tatattgagt tttacaaaaa aattggtatg ccaacaactc taaaagaaat gcatttggat
     9421 caagttggat atgatgattt aataaaagtt ggtaaacaag caactatgga gggtgagaca
     9481 attcatcaga tgccgtttaa gatttcgcct tcagatgttg ctcaagctat tatcgctgta
     9541 gatgcctatg taaattcaaa ataaacaata aggactactg ttttccaaat ggtagtcttt
     9601 tattgatccc cgtattgaat tctatagaag attgaaatag gatgagaaca aatcgattgg
     9661 gaaagtaaaa ttaatttcta taaatgtttt agcaattgtt tcgtactatt tcagattcag
     9721 tctactatac gttcttcata aatcaaaaag cgacataggt tgtcggctat ttattgtgaa
     9781 tacattaatt agcattccag ttttatcttc ggtctaaaat aagtattttg tgctatacga
     9841 gataagcgtc ttgacttact ccttgattta ctgcataaca atgggataaa aagtgggaga
     9901 tagagcaatt catagtcatc aaaattaatg agatacagta tacagttttt cctttaaaca
     9961 catttcaaat tccctcaaaa atggtataat agtaacatca caaaattgga gagagaccat
    10021 gagtttttac aatcataaag aaattgagcc taagtggcag ggctactggg cagaacatca
    10081 tacatttaag acaggaacag atgcatcaaa acctaagttt tatgcgcttg atatgttccc
    10141 ttatccgtct ggagctggtc tgcacgtagg acacccagaa ggttatactg caaccgatat
    10201 cctcagtcgt tacaaacgtg cgcaaggcta caatgtcctt cacccaatgg gttgggatgc
    10261 ttttggtttg cctgcagagc aatacgctat ggatactggt aatgacccag cagaatttac
    10321 agcggaaaac attgccaact tcaaacgtca aatcaatgcg cttggatttt cttatgactg
    10381 ggatcgtgaa gtcaatacaa cagatccaaa ctactacaag tggactcaat ggattttcac
    10441 caagctttac gaaaaaggct tggcctatga agctgaagtg ccagtaaact gggttgagga
    10501 attgggaact gccattgcca atgaagaagt gcttcctgac ggaacttctg agcgtggagg
    10561 ctatccagtt gtccgcaaac caatgcgcca atggatgctc aaaatcacgg cttacgcaga
    10621 gcgcttgctc aatgacttag atgaactaga ttggtcagag tctatcaagg atatgcaacg
    10681 caactggatt ggtaaatcaa ctggtgccaa tgtaactttc aaagtaaaag gaacagacaa
    10741 ggaatttaca gtctttacta ctcgtccgga cacacttttc ggtgcgactt tcactgtctt
    10801 ggctcctgaa catgaattag tagacgctat cacaagttca gagcaagcag aagctgtagc
    10861 agactataaa caccaagcca gccttaagtc tgacttggtt cgtacagacc ttgctaagga
    10921 aaaaactggt gtttggacag gtgcctatgc catcaaccct gtcaatggta aggaaatgcc
    10981 aatctggatt gcggactatg ttcttgctag ttatggaaca ggtgcggtta tggctgtgcc
    11041 tgcccacgac caacgtgact gggaatttgc caaacaattt gaccttccaa tcgtcgaagt
    11101 acttgaaggt ggaaatgtcg aagaagctgc ctacacagag gatggcctgc atgtcaattc
    11161 agacttccta gatggattga acaaagaaga cgctattgcc aagattgtgg cttgcttgga
    11221 agaaaaaggc tgtggtcagg agaaggttac ctaccgcctc cgcgactggc tctttagccg
    11281 tcaacgttac tggggtgagc caattccaat cattcattgg gaagatggaa cttcaacagc
    11341 tgttcctgaa actgaattgc cgcttgtctt gcctgtaacc aaggatatcc gtccttcagg
    11401 tactggtgaa agtccactag ctaacttgac agattggctt gaagtgactc gtgaagatgg
    11461 tgtcaaaggt cgtcgtgaaa ctaacaccat gccacaatgg gctggttcaa gctggtacta
    11521 cctccgctat attgacccgc acaatactga gaaattggct gatgaggacc tcctcaaaca
    11581 atggttgcca gtagatatct acgtgggtgg tgcggaacat gctgtacttc acttgcttta
    11641 tgctcgtttc tggcataaat tcctctatga cctcggtgtt gttccgacta aggaaccatt
    11701 ccaaaaactc tttaaccaag ggatgatttt gggaacaagc taccgtgacc accgtggtgc
    11761 tcttgtggca accgacaagg ttgaaaaacg tgatggttcc ttctttcata tagaaacagg
    11821 ggaagagttg gagcaagcgc cagccaagat gtctaaatcg ctcaagaacg ttgttaaccc
    11881 agatgatgtg gtggaacaat acggtgccga tacccttcgt gtttatgaaa tgtttatggg
    11941 accactcgat gcttcgattg cttggtcaga agaaggtttg gaaggaagcc gtaagttcct
    12001 tgaccgagtt taccgtttga ttacaagtaa agaaatcctt gcggaaaaca atggtgctct
    12061 tgacaaggct tacaacgaaa cagtcaaagc tgttactgag caaattgagt ctctcaaatt
    12121 caacacagct attgcccaac ttatggtctt tgtcaatgct gctaacaagg aagataagct
    12181 ttatgttgac tatgccaaag gctttattca attgattgca ccatttgcac ctcacttggc
    12241 agaagaactc tggcaaacag tcgcagaaac aggtgagtca atctcttatg tagcttggcc
    12301 aacttgggac gaaagtaaac tggttgaaga cgaaatcgaa atcgttgtcc aaatcaaagg
    12361 taaagtccgt gccaaactca tggtcgctaa agacctatca cgtgaagaat tgcaagaaat
    12421 tgctctagcg gatgaaaaag tcaaagcaga aattgacggt aaggaaatcg tgaaagtgat
    12481 tagtgtacca aataaattgg ttaatattgt tgtaaaataa ccaatttatt tgctgatttc
    12541 caacctcaaa cagtttccca aactgtttga gccaactaaa ctcgttaata tcgttgtgaa
    12601 ataaggtagg aatccttcag agtagaatct ggaggatttt ttgaatcttc ttatgaaagt
    12661 atggtatact atgggcaact ataaagtttg aaaagtgaaa aaaggagaaa gctatgccag
    12721 taaatgaata tggtcaaatg attggggagt caatggaagg ttatacacca ggtgaactgc
    12781 cttctattga tttcttagaa gggcgttatg ctaggataga ggctctttca gtggaaaagc
    12841 atgcggagga tttgctagct gtttatggcc cggatactcc tcgggagatg tggacctacc
    12901 tttttcagga gccagtagca gatatggggg agctggttag ccttttacat cagatgttgg
    12961 ctcgtaagga ccgtttttac tatgcaatca tagacaaggc gactggtaag gctttgggat
    13021 ctttttctct catgcgcatt gaccagaata accgagtaat agaagtcgga gcagtcactt
    13081 tttctccaga gctaaggggt acacggatag gaactgaagc tcagtatctc ctagctcgct
    13141 atgtttttga ggagctaaac tatcgtcgct acgagtggaa atgcgatgcc ttaaatctgc
    13201 catccagacg agctgcggag cgtttgagct ttatttatga aggaaccttc cgtcaggcag
    13261 tggtttataa gggacgtacg agagatacgg attggttgtc tatgattgat aaggactggc
    13321 ctcaagtcaa agatcgtttg gaaacatggt tgcgtcctga aaattttgat aaaaatggac
    13381 agcagtacaa gagcttgaga gaactttaag aggtgttgag atgattacta ttaaaaagca
    13441 agaaattgtc aagctagagg atgttttaca tctctatcag gctgtcggtt ggacaaatta
    13501 tacccatcaa ccagagatgc tggagcaggc cttatctcat tcattagtaa tttatctggc
    13561 acttgatggt gatgctgtgg tgggcttgat tcgtttggtt ggagatggat tctcatcagt
    13621 attggttcag gatttaatcg ttttaccaat ctatcagcgt caaggaattg gtagtgcctt
    13681 gatgaaagag gctttagagg attacaaaga tgcctatcaa gtccagctgg tgacagaaga
    13741 gacagaaaga accttgggct tctatcgttc tatgggcttt gaaatcttat ccacctataa
    13801 ttgtataggg atgacttgga tgaatcgtaa aaaataacaa aacttgtttt ttcttaagca
    13861 aaatttaagg atggtctagt attatatagt cattaaataa agacctccta actttattta
    13921 ataaaatcct aaactttttt catcacaatc tcctaatgaa gccacccaat caggtggctt
    13981 ttttgcgtgg tgaggtgctg gtgatagaaa ttttttgcaa aatagtaaaa ttttagaaaa
    14041 gttaagctag ttttaagttt cgtcttgtat catgtagtta ttaaataaag acctcctaac
    14101 tttatttaat aaaatcctaa acttttcttt ttcataataa tctcccttaa cttcacccaa
    14161 tcaggtggag ttttttagct ctatttcagg cttttgggga ctattctaaa aataattttt
    14221 cgatattttt cggtattttt cggattttgg tcggggaatt ggcggggact tttttagcga
    14281 atataactaa gaaataggtc tgtggtcgct tcagctagtt caaactcaat ttgattgtaa
    14341 gtgactgtta attgaagaac tggaactact gtaataatga ttttgcttgt ctagtagtgg
    14401 cgtattaaat gagaagtaac atgtaagatt gtctcttcgt ttacgaaatc aaaatttcta
    14461 tgaaattgat agaatcccta acgttctctt aatcttaacc gtcttgtcgt acagcggttg
    14521 aagaaaatgt aaacctttga caaaattcgt gaactatggg ataataaaaa ggaattgagt
    14581 actagttcta tatcataggc tagaaaagac cccaagctca cgaccaaata agcttgaggt
    14641 cttttttgac actatttgtc cttgtttagc catttatcga ctatacgaag aacgacaccg
    14701 accacaattg gtccgatgat agttttgagt actaattcca tcatgggcta tctcacctcc
    14761 tttcgtaggc ggtgtagcag tgtcgtagaa tattatacca cataagtgct aaacttagga
    14821 gtcacccaat caggtggctt ttttgtttgt ggcttggttt tttgatataa tagagccatg
    14881 agtagaattt tagataatga gataatgggg gatgaggagt tagtagaacg cacgctccgt
    14941 cctcagtatt tacgtgaata tatcggacag gataaggtca aggaccagct acaaatcttt
    15001 attgaagctg ccaaaatgcg ggatgaagcg ctggatcatg tgctcttatt tgggcctcca
    15061 ggtctcggga aaacgaccat ggcctttgtt attgccaacg aactgggagt caatcttaag
    15121 cagacgtcgg gtccagtcat tgaaaaagcc ggagatctgg tagctatttt gaatgagtta
    15181 gagcctgggg atgtactttt tattgatgag atccatcgtt tgccaatgtc agtggaagag
    15241 gtgctttata gtgctatgga ggacttctac atcgatatta tgattggggc tggtgagggt
    15301 agtcgtagtg ttcatttgga gttaccacct tttaccttga ttggtgcgac gactcgggct
    15361 ggtatgctct ccaatccgct acgggcacgt tttgggatta caggccatat ggagtattat
    15421 gcccatgctg gcttgacaga aattgtcgag cggacggcag atatttttga gatggaaatc
    15481 actcatgagg cagcatctga gttggcccta cgtagtcgtg ggacccctcg tattgccaat
    15541 cgtctcctca agcgcgtgcg cgattttgcc cagataatgg ggaatggggt aattgatgat
    15601 attattaccg ataaggcttt gactatgctg gatgttgacc atgaaggttt ggactatgtg
    15661 gatcaaaaaa tccttcgtac catgattgag atgtacagtg gaggacctgt tggtctagga
    15721 actctttctg tgaatatcgc cgaagagcgt gagacagttg aagatatgta tgagccttac
    15781 ttgattcaaa aaggttttat catgcggaca cggtctggac gggtggcgac tgctaaggca
    15841 tatgagcact taggttatga atacagtgaa aaataagcaa gaaatcttag aggcttttag
    15901 agaaaatcca gatatgatgg ccattctgac gatcatccga gaccttggtc tgaaagactc
    15961 gtggttggca gcaggttctg tcagaaattt catttggaat cttttgtcag acaaatcccc
    16021 ttttgatcat gaaacagata tagatgtgat tttctttgat ccagattttt cttatgagga
    16081 aaccttatta ctggagaaaa agctgcgaga ggattttcct cagtaccagt gggaattgaa
    16141 aaatcaggtc tatatgcatc agcacagtcc tcacactgct tcctatacca gttctcgtga
    16201 tgctatgagt aagtatccag aacggtgtac gacagttgga ctgcgcttga atgaagaatc
    16261 agattttgaa ctctatgcac cttatggttt ggaggatatt ttgaattttc aagttcgtcc
    16321 aactcctcat ttcttagaaa atgaagaccg aatggaactc tatcaaacac gtttatccaa
    16381 gaaaaattgg caggagaaat ggaaaaattt gatttttaaa aatacttaag gaaactttaa
    16441 gctagggagt gtacactaag ttcataagtt aagaagacct taacttaaac tcctaaaact
    16501 ttttcataat aatctcccta taaaaataaa gtcgcctaat caggcggctt atttttttga
    16561 aaaatgggct tggtgcctga gaataaatag cttagtgata gaagaaaatg gggaaatatg
    16621 gtataatgaa acgatagatt tttgaatagg aataagatca tgtttggatt ttttaagaaa
    16681 gataaggctg tggaagtaga ggttccgaca caggttcctg ctcatatcgg catcatcatg
    16741 gatggcaatg gccgttgggc taaaaaacgt atgcaaccgc gagtttttgg acacaaggcg
    16801 ggcatggaag cattgcaaac cgtgaccaag gcagccaaca aactgggcgt caaggttatt
    16861 acggtctatg ctttttctac ggaaaactgg acccgtccag atcaggaagt caagtttatc
    16921 atgaacttgc cagtagagtt ttatgataat tatgtcccgg aactacatgc gaataatgtt
    16981 aagattcaaa tgattgggga gacagaccgc ctgcctaagc aaacctttga agctttaacc
    17041 aaggctgagg aattgactaa gaacaacaca ggattgattc ttaattttgc tcttaactat
    17101 ggtggacgtg ctgagattac acaggcgctt aagttgattt cccaggatgt tttagatgcc
    17161 aaaatcaacc caggtgacat cacagaggaa ttgattggta actatctctt tactcagcat
    17221 ttgcctaagg acttacgaga cccagacttg attatccgta ctagtggaga attacgtttg
    17281 agcaatttcc ttccatggca gggagcctat agtgagcttt attttacgga caccttatgg
    17341 cctgattttg acgaagcagc cttgcaggaa gctattcttg cctataatcg tcgccatcgc
    17401 cgatttggag gagtttagga ggaaatatga cccaggattt acagaaaaga accttgtttg
    17461 cagggattgc cctggctatt ttcctaccaa ttttaatgat tgggggcctc ttgcttcaga
    17521 tagcaatcgg aatcatagcc atgctagcca tgcatgaact tttgaagata agaggtctag
    17581 cgaccatgac gatggagggc ctcttgactc tctttgcaac ctttgcatta accattccct
    17641 tggagaatta cctgactttt ttgccagttg atgggaatgt ggttgcctat agtgttttga
    17701 tttcaatcat gttaggaacg accgttttta gcaagtctta tacgattgag gatgcggttt
    17761 tccctcttgc tatgagcttc tacgtgggct ttggatttaa tgctttacta gatgctcgtg
    17821 ttgcaggttt ggacaaggct ctcttagcct tgtgtatcgt ctgggcgaca gacagtggtg
    17881 cctatcttgt tgggatgaac tatgggaaac gaaagttagc accaagggta tcgcctaata
    17941 aaacccttga gggtgccttg ggtggtattt taggagcaat tttagtaacc attatcttta
    18001 tgatagttga cagtacagtt gctcttccat atggaattta caagatgtca gtctttgcta
    18061 ttttctttag cattgctgga caatttggtg atttactaga aagttcgatc aaacgtcatt
    18121 ttggtgttaa ggattctggg aaatttatcc ctggacatgg tggtgttttg gatcgtttcg
    18181 atagtatgtt gcttgtattt ccaatcatgc acttatttgg actcttttaa tcaaaagacg
    18241 gaggaaacgc tatgctcgga attttaacct ttattctggt tttcgggatt attgtagtgg
    18301 tgcacgagtt cgggcacttc tactttgcca agaaatcagg gattttagta cgtgaatttg
    18361 ccatcggtat gggacctaaa atttttgctc acattggcaa ggatggaacg gcctatacca
    18421 ttcgaatctt gcctctgggt ggctatgtcc gcatggccgg ttggggtgat gatacaactg
    18481 aaatcaagac aggaacgcct gttagtttga cacttgctga tgatggtaag gttaaacgca
    18541 tcaatctctc aggtaaaaaa ttggatcaaa cagccctccc tatgcaggtg acccagtttg
    18601 attttgaaga caagctcttt atcaaaggat tggttctgga agaagaaaaa acatttgcag
    18661 tggatcacga tgcaacggtt gtggaagcag atggtactga ggttcggatt gcacctttag
    18721 atgttcaata tcaaaatgcg actatctggg gcaaactgat taccaatttt gcaggtccta
    18781 tgaacaattt tatcttaggt gtcgttgttt tttgggtttt aatctttatg cagggtggtg
    18841 tcagagatgt tgataccaat cagttccata tcatgcccca aggtgccttg gccaaggtag
    18901 gagtaccaga aacggcacaa attaccaaga ttggctcaca tgaggttagc aactgggaaa
    18961 gcttgatcca agctgtggaa acagaaacca aagataagac ggcaccgact ttggatgtga
    19021 ctatttctga aaaggggagt gacaaacaag tcactgttac acccgaagat agtcaaggtc
    19081 gttaccttct aggtgttcaa ccgggggtta agtcagattt tctatccatg tttgtaggtg
    19141 gttttacaac tgctgctgac tcagctctcc gaattctctc agctctgaaa aatctgattt
    19201 tccaaccgga tttgaacaag ttgggtggac ctgttgctat ctttaaggca agtagtgatg
    19261 ctgctaaaaa tggaattgag aatatcttgt acttcttggc aatgatttcc atcaatattg
    19321 ggatttttaa tcttattccg attccagcct tggatggtgg taagattgtg ctcaatatcc
    19381 tagaagccat ccgccacaaa ccattgaaac aagaaattga aacctatgtc accttggccg
    19441 gagtggtcat catggttgtc ttgatgattg ctgtgacttg gaatgacatt atgcgactct
    19501 tttttagata atcgaggaat attatgaaac aaagtaaaat gcctatccca acgcttcgcg
    19561 aaatgccaag cgatgctcaa gttatcagcc atgctcttat gttgcgtgct ggttatgttc
    19621 gccaagtttc agcaggtgtt tattcttatc taccacttgc caaccgtgtg attgaaaaag
    19681 ctaaaaacat catgcgccaa gaattcgaaa agattggtgc tgttgagatg ttggctccaa
    19741 cccttcttag tgcagaattg tggcgtgaat caggtcgtta cgaaacctat ggtgaagacc
    19801 tttacaaact aaaaaaccgt gaaaaatcag actttatctt aggtccaact cacgaagaaa
    19861 cctttacagc tattgtccgt gattctgtta aatcttacaa gcaattgcca ctcaaccttt
    19921 atcaaattca gcccaagtat cgtgatgaaa aacgcccacg taatggactt cttcgtacac
    19981 gtgagtttat catgaaggat gcttatagtt tccacgctaa ctatgatagt ttggatagtg
    20041 tttatgatga gtacaaagca gcctatgagc gtattttcac tcgtagtggt ttagacttca
    20101 aggctattat tggtgacggt ggagccatgg gtggtaagga tagccaagaa tttatggcca
    20161 ttacatctgc tcgtacagac cttgaccgct gggttgtctt ggacaagtca gttgcctcat
    20221 ttgacgaaat tcctgcagaa gtgcaagaag aaatcaaggc agaattgctc aaatggatag
    20281 tctctggtga agataccatt gcttactcaa gtgagtctag ctatgcagct aacttagaaa
    20341 tggcaacaaa cgagtacaaa ccaagcaacc gtgttgtcgc tgaagaagaa gttactcgtg
    20401 ttgcaacgcc agatgttaaa tcaattgatg aagttgcagc cttcctcaat gttccagaag
    20461 aacaaacgat taaaaccctc ttctacattg cagatggtga gcttgttgca gcccttctag
    20521 ttggaaatga ccaactcaac gaagtcaagt tgaaaaatca cttgggagca gatttctttg
    20581 acgttgctag cgaagaagaa gtggcgaatg ttgttcaagc aggatttggt tcacttggac
    20641 cagttggttt gccagagaat attaaaatta ttgcagatcg taaggtgcaa gatgttcgca
    20701 atgcagttgt cggtgctaac gaagatggct accacttgac tggtgtgaac ccaggccgtg
    20761 attttactgc agaatatgtg gatatccgtg aagttcgtga gggtgaaatt tccccagatg
    20821 gacaaggtgt ccttaacttt gcgcgtggta ttgagatcgg tcatattttc aaactcggaa
    20881 ctcgctactc agcaagcatg ggagcagatg tcttggatga aaatggtcgt gctgtgccaa
    20941 tcatcatggg atgttacggt atcggtgtca gccgtcttct ttcagcagtg atggagcaac
    21001 acgctcgcct ctttgttaac aaaacgccaa aaggtgaata ccgttacgct tggggaatca
    21061 atttccctaa agaattggca ccatttgatg tgcatttgat tactgtcaat gtcaaggatg
    21121 aagaagcgca agccttgaca gaaaaacttg aagcaagctt gatgggagct ggttatgaag
    21181 tcttgacaga tgaccgtaac gaacgtgtcg gtgttaaatt tagcgatagt gacttgattg
    21241 gtcttccaat ccgtatcact gttggtaaaa aagcggccga tggcattgta gaagttaaga
    21301 tcaaggcaac tggtgacacc attgaggttc atgcagataa cgtgcttgaa acgcttgaaa
    21361 tcctaagcaa gaaataaaaa ctataatcag aagaaaaaca aggaaaaaat gtaactagtt
    21421 tttaccttgt tttttctgta taatgggaga aatgagtaga taaagaggta aatgttatgc
    21481 taagatttcc aaaggatttt gtctggggat cctctacttc tggaccgcag acagaaggac
    21541 gtgtagctgg tgacggtaag ggagacaatc tctgggatta ctggttccaa gtggagccaa
    21601 atcgttacta taatgggatt ggttcagata agacatcgac tttttatgaa aattgggagc
    21661 gggatattga gcttttgtta gagactggtc acacagtctt tcggacttct attcagtggt
    21721 cacggatttt tccacaaggc tgtggaaaag tcaaccctca aggtgtggat ttttatcgta
    21781 aggtctttga ggctattaag gctaaaggaa ttcgtctgtt agtcaatctc tatcattttg
    21841 atttaccttt tgcccttcaa gaggatggtg atggttggga aaataaggcg acagtctcag
    21901 cctatgaaga ctatgctcgt ttttgttttg agacttatgg agatttagtg gatcaatgga
    21961 ttacctttaa cgagcccatc gttcctgtag aatttggtta tttttatgat gcccattatc
    22021 cacataaggt ggatgcagag gcagctgtta aggtagccta tcatacacaa ttggccagca
    22081 gccgggctgt taaggcttgc catgaacttt tgcctgattc caagattggg attgtcctca
    22141 acttgacacc ggcttatcca cgtagccagc atcctgctga tgtcaaggca gctcgtattg
    22201 cggccctttt tcaggcccaa tctttcttag atccatctgt cttggggact tatccacagg
    22261 agttggtaga aatcttgcat gaacacggtc ttttacctga tgctacagag gaagagttgg
    22321 aactcattcg tgataatacg gtggacttcc ttggtgtgaa ctactatcaa cctttgcgtg
    22381 ttatggctcc tcgatttgct aagcatccag atagtccact cttaccagaa catttttacg
    22441 agccttatgt gatgcctgga cgtaaaatca attctcaccg tggttgggag atttatgagc
    22501 aagggattta tgacatcgcc caaaatatca aggaaaatta tggcaatatt gagtggatgt
    22561 tgactgagaa tggtatgggt gttgaagggg aagaaaaatt ccgtcaagat ggaatgattc
    22621 aagatgatta ccgtattgac tttgtaaaag gtcatcttcg tgaacttcac cgtgccattg
    22681 aagatggtgc caactgtaag ggctacttga tttggacctt tattgactgc tggtcatggc
    22741 tcaacagcta taaaaatcgc tatggtttgg tcgaattaga cttggaaacg caagaacgtc
    22801 gtctgaagaa atcaggccac tggttcaaag aattaagcga taataatgga ttttaaaaag
    22861 gactctgact gattatccca atcggtcaga gttttttgct tacaggagct taatttgaac
    22921 tataccaatt tttactcttg acaagtgaaa gaaacaagta tatactgttt ttgctgattc
    22981 tataaaagat gaattagact ataccaattt taaggagaaa gcacagcttg cctgtgtcgt
    23041 atatactatg tgtggaattg ttggtgttgt tggaaacaca aatgcaactg atattttgat
    23101 tcaagggctt gaaaagcttg aataccgtgg ctatgattct gcgggaattt ttgtcctaga
    23161 tggtgctgat aaccatttgg tgaaggctgt tggtcgtatc gcagaattgt ctgccaagac
    23221 agctggtgtt gagggaacaa ctggtatcgg acatactcgt tgggcaactc atgggaaacc
    23281 aacggaagac aatgctcacc cacaccgctc tgagacagaa cgttttgtct tggttcacaa
    23341 tggggtgatt gaaaactacc ttgaaattaa agaagaatac cttgctgggc accacttcaa
    23401 agggcaaaca gatacggaaa tcgccgtaca tttgattgga aaatttgcgg aagaagacgg
    23461 tctctcagtt cttgaagcct ttaaaaaagc tcttcatatt atccgtggtt catatgcctt
    23521 tgccttgatt gactctgaaa atccagatgt catctatgta gcgaaaaaca aatctccact
    23581 tttgattggt cttggggaag gctacaatat ggtctgctca gatgctatgg ctatgattcg
    23641 tgaaaccaac caatacatgg aaattcatga ccaagagttg gtaatcgtca aggctgatag
    23701 cgtggaagtt caagactatg atggtaacag tcgtgaacgt gctagctata ctgcggaact
    23761 tgacttgtca gatatcggta agggaactta tccttactac atgcttaagg aaattgatga
    23821 gcaaccaact gttatgcgta aactcattca agcctacacg gatgatgctg gtcaagtagt
    23881 gattgatcct gctatcatta aggctgttca agacgcagac cgcatctaca tccttgcagc
    23941 tggaacatct taccatgcag gatttgcttc taagaaaatg ttggaagaat tgacagatac
    24001 accagttgaa cttggcatct catctgagtg gggctacggt atgccacttc tcagcaagaa
    24061 accactcttc atctttatca gccaatctgg tgaaacagcg gatagtcgtc aagttttggt
    24121 caaggctaat gaaatgggaa ttccaagctt aacagtgaca aacgttccag gttcaaccct
    24181 ctcacgtgaa gccaactata ccatgctcct tcacgcaggt cctgaaattg ccgtggcatc
    24241 aactaaagcc tatacagcgc aaatcgcagc ccttgccttc cttgcaaaag cagtcggaga
    24301 agcaaatggt aatgctaaag cgcaagcctt tgacctggtt catgaattgt caatcgtagc
    24361 tcagtctatc gaatcaactc tttcagagaa agaaaccatt gaagccaagg ttcgtgaact
    24421 tcttgaaaca actcgtaacg ccttttacat cggacgtggt caagattact acgtagccat
    24481 ggaagcaagt ctcaaactca aagagatttc ttatatccag tgtgaaggtt ttgcggcagg
    24541 agaactcaag cacggaacca ttgccttgat tgaagaagga acacctgtct tggctctctt
    24601 gtcagatcca gtccttgcca accacactcg tggaaatatc caagaggtgg cagcccgtgg
    24661 tgctaaggtc ctcactatcg cagaagaaaa tgttgctaaa gataccgacg atatcgtcct
    24721 tacgactgta cacccttacc tctcaccaat ttcaatggtc gtaccgacgc aattggttgc
    24781 ttactttgca accctccacc gtggcctcga tgtggataaa ccacgtaacc ttgctaaatc
    24841 agtaacggta gaataagcta aaaaagtcta gttatctagg ctttttctaa tgagcaaatt
    24901 ggttgcttgt actcaagatt cgtgttagaa taatttttca aattgaagga cagagataga
    24961 caaggagaat cacaatggta gaattgggaa tttcaacatt tggggaaata acggagcttg
    25021 aagggactgg acaaacttac agtcatgctg aacgcattcg ccagttggtg gcagagattg
    25081 agctggctga caaggttggt ttggacgtat atgggattgg cgagcaccat cgggcggatt
    25141 ttgcagtatc agccccagag attgtcctgg ccgctggggc agtcaatacc aagaaaatcc
    25201 gtttgaccag tgcagtcagc attctgtcaa gcatggatcc gattcgtttg ttccaacagt
    25261 atgccactat cgatgctttg tcaaatggac gatcggagat tatggctgga aggggctctt
    25321 tcacggaatc tttccctctg tttggttatg acttgaaaga ctacgactct ctttttgatg
    25381 agaaattaga cttgcttcag ttagtcaatg aaaagaccaa gttagactgg caaggtcgat
    25441 tgactcaaac gattgctggt aaagaagttt atcctcgccc agttcaggac aaattgccct
    25501 tgtggatagc tacaggtggt catgtcgaat caacagtgaa gattgctcag gctggtctac
    25561 cgattgtata tgctattatt ggtggtaatc cacgttattt taaaaagttg attcaggctt
    25621 atcgtgagat tggaagcgaa gcgggccatg ctgacaaaga cttgaaagtg ggagcccatt
    25681 cttgggggtg gattgcggaa gatggtgagc aggcggtgaa agattatttc catccgacta
    25741 agcaagtggt ggatgctatt tccaaagacc gtccgcactg gcaggaattg cgttatgagc
    25801 aatatttgga gcaggtaggg ccaaatggcg ccatgtttgt tggcaatcca gatcaggtgg
    25861 ccgaaaaatt gattcgcatg atagaggatt taggattgga ccgcttcatg cttcatctac
    25921 cgcttggttc tatgcctcat gaccaggttc tgagagctat tgaactcttc ggaacacaag
    25981 ttgcacccaa agtacgagct tattttgcta tgaaagaggc ttaataaaaa atcctaatca
    26041 agtttattag gacaacaaat attgtacaaa aattaatccc ccgagctata atgcttgggg
    26101 gatttttcta taggagggct agtttagttc tcttttttat tttttagtaa gaaaccgaga
    26161 ccaaggagcg caaggaggct gattcctgca aataggagtt tgttttcgtt tttgattcct
    26221 gtatttggaa gttcagcttg tttatctggg gttgcaggta tattttcctt gctagagttt
    26281 tctaccgatt cgtttcgaac cgcttctttt acagatgctt cttgtgcttc ttgtgctggt
    26341 tgttcagctt gtgaatcagc tgtagcttgg ctaggtttat tttccgcatc agctactttg
    26401 gcatctggtt tagtagaatc aggtctagct tctggagctg ggtcttgatg tgcagggtga
    26461 gaagcttcat tttgatgttc aggcttggaa ggggttgagt ctggtttctc ttctgcagtt
    26521 gactcatggc tagttccatt ttgagagact cgaagaacag tagctgtaag ggcattcaat
    26581 ttcaagcctt tttcagtcca ttcaagtcct ttcgggttgg caattttgac tgatcctgct
    26641 tggttttcat ctgccaaaac ttccgcattt cttagatgtg caaaggcagt tcccaaatta
    26701 aattcgcgag ctttttcatc cgcattgaca aagactgcgt agatatcgcc gtttggagca
    26761 gtgatttggt agccaatcac tacatcctct ttttccacac cattttggcc tgggacagtg
    26821 atgaggtgga cacggtcttt gatatcttgg agactcttaa gtcggaaggc atctgtagat
    26881 tgacgaaggg caatcaaacc tttcatatag tcacggctct tgacattttc aggataagct
    26941 ttaccatctg tagccttagt ccagtcaaac ttgttgactg cgtcgctaga atcgtaagaa
    27001 tcatggatga agtaaggata gtcaaatggg ttgccgtcct tatcacgcaa caagtgagat
    27061 ttgtttggaa ccttatcctc tgctactgga gtcttgtagg ctgggtcacg gaattgttta
    27121 gtacgtccat attcctgacc ggagtggata aatggagttc cttgagctgt caagaccatg
    27181 agatttccaa gtcgtaaacg acggtggatt tcagcatagt tctcagcctt gcttgggtct
    27241 tttttgatag actgggcaat gatgtcaaag agggtcaagt tatcatgggc tgctatgtat
    27301 tggatgacat ctccagggct gtcagcttca aagttagttg gttgagcaat gagattttta
    27361 aagatggtgt tgacatcacg cttgccacct gtgataaagg caggttgacc ttcgtttgga
    27421 taaccagatt tgaggttgtt acggatgtca tctgaaaaga cagcgacagt atcggtatgt
    27481 ttcatccaat cttggtcagc agctttagta ggcatgtttt catcaccggc ataggttctc
    27541 caaccttcac caagcatgat gaggtttgga ttgagggcgc gtgcagcctt gtaagcttct
    27601 tcgatagaag cggcgtcatg gtctcccatc atatcgaaac ggaatccatc cactttgtag
    27661 gtatcaacta ggtatttgat agagtcaact aggagccgtt tggtcatatg gtgggttgtt
    27721 cccaagcgtc caccaccaaa gctagttcga ggtgtgccat cggcatccat aaagtggtag
    27781 tagtttggct ctaggtcttc aaagatatcg actttggctg tgtggttata aacgacatct
    27841 aggatagctc ccataccacg tttgtggatt tcgttgatga ggtttttaaa ttctgcgatt
    27901 cgtttttctg gattcttagg atcgcttgag tacataccag tcaaggagaa gtagttttga
    27961 gggtcatatc cccagttgta gttgctgttg cttgaagcgt agtcagacaa gcgttcatgg
    28021 tttttcaatt cattgacaaa gtagtaagac aagactggaa ggagctggat atgggttaca
    28081 cccaagtctt tgagatagtc tagtttttca atgaaggctt caaaagtccc aaatggtttg
    28141 gtcaagtctt ttgcaatggc aggatctgaa gtgaagtcac gcacatgagc ttcgtagata
    28201 acggcgtctt cacgagtctt gaaattgtga atcttaccat aagtcaagtc ttgaggtccg
    28261 agtttagctg gatctacaaa ggcggcttta gccactttat gggtatcgtc aattttggca
    28321 tcgtcgctat tccaagcagc aagagattta gcgtaaggat cgagtgcaag aacagtttta
    28381 ccttgacgct cgatttggta ttgataatag tagccagtga aatctgtgat tccgagtttg
    28441 tttgtgctgt ctagagtttg tttccaagtt cctctttccc ctttttcgag agcgacagtt
    28501 ccaactactt tgtcagggtc attcttgtcg tagacaacaa cagaaacctt atcagcactt
    28561 ggtgaccaaa gggtcaaatc aacttgtttt ccttcttctt ttaggtcagc tcccagtttg
    28621 ccatcatagc tgtatgtctc atctttcagg tgccagcttg ttttggtagt gaattggtcg
    28681 gaattgtagc taacagtata agggtgtttt gtgtcagaga aatctccgct gtaggtcact
    28741 ttcttaccag cttcatcgat tgcaacatcg gtaatagtta ccttgtttcc taggtgatta
    28801 gtgatgttgg agtgtttgag gatatcttct tttttagcac cgacaagtgt tgaaaagcta
    28861 ctttcaatgc tagaagtgcc tacgtgttgg gctcctgtca tacggatatc atggacatag
    28921 tatggatttg tgtaaatcga ttcatcatcg tcttttagga aaatttggct atgatttttc
    28981 aaatctgtga acttataatt ttctttacgg attttcacgt cgtctccttg tttgctctca
    29041 tctagtaata aaaatccaaa ttctcttgcg gcttcattaa gaggaatgtc gatatagcgg
    29101 ccatatttgc ctgtagccgt aaagtctgtt ccgtcaggcc attgagcgct acttggattt
    29161 ttcacatctc cccagtacca gagagatttc ttgtcatagt tgccatctgt gcggtagtag
    29221 ttgacgcgaa cagttcctgc aggctgtggc tcgtaagaga aaaccttgta atcttggtct
    29281 aaccaagctt cgttcatttt tggaactagt ttttctacag atttatcgcc ggttagattt
    29341 tttccagctg tattgttgat gaggaagcta attttcttgg cttgttctcc ctttaatttg
    29401 acatctaggt aatagccgta gtcatctttc ttggcatcct tgaaggacaa agctccgttt
    29461 ggccagtttt cagatggttt ttcaacatcg tcccaagtcc atagtccttg agcatccttg
    29521 ttttcttcag gaagtttttt gacatggata cggaagtagt tatcttcgat gggctcttct
    29581 gccttagttt cagttgttac tggactagta gaagtagttg gctctgttgc aggtttttct
    29641 tctgttttct ctagggaagc gtttgcattt ctaggtgaag aaatatcact ttcgttctta
    29701 ccagagccag ctgctgtatc agtaagaggt tgggcaaggg tggttgtatt tctgttgttg
    29761 ggttcgttag tggttggtgt actttcgtcg gatgagatag ttggtgtagc catggcaagc
    29821 aagacaaggc ttgcgccgat aaggacagaa ccagttccat ttttgaggga acggatgctg
    29881 tagaccattt ttttctcagt gtgagatggt gtttttctca taatgattct ccaatcaata
    29941 aatttctata tcagtatagc atgtagtaaa acaatatgca agcgttttct ttgatttgtg
    30001 aaaaaaattc ttacttttga gaagttttct gtactatttt atatatcagt ataaatgacg
    30061 gagataaaaa tgtcacataa gccaagccgt attattagga agatgatgtg ttcccagcta
    30121 tttttattca gaaattgatc tctaacatta ccaataaaaa agaaaaatat cttgacaagc
    30181 aagggaaaat tttgttacaa taatagacgg tactttttac ttttggtctc tcaagagtgt
    30241 acagggacgt gctgacaaat gttgcaaaag tacacacaga tgatatctgt caccaagtgt
    30301 atcatcacca aaaataaaaa aacacaggag aatgtagatg cctacaatta accaattggt
    30361 tcgcaaaccg cgtaaatcaa aagtagaaaa atctaaatca ccagctttga acgttggtta
    30421 caatagtcat aaaaaagttc aaacaaacgt ttcttcacca caaaaacgtg gtgttgcaac
    30481 tcgtgttgga acaatgacac ctaaaaaacc taactcagcc cttcgtaaat tcgctcgtgt
    30541 acgtttgagc aaccttatcg aagttactgc ctacatccca ggtatcggac acaacttgca
    30601 agagcacagc gtggtgcttc ttcgcggtgg acgtgtaaaa gaccttccag gggtacgtta
    30661 ccatatcgtc cgtggtgcac ttgatactgc aggtgttaac gatcgtaaac aaggccgttc
    30721 taaatacggt actaaacgtc caaaagcata aggaaagggg ataaagagaa atgagtcgta
    30781 aaaatagagc tccaaaacgt gacgtattgc cagatccgct atacaattca caactagtta
    30841 ctcgtcttat caaccgcgtt atgcttgatg gtaaacgtgg tactgctgct tcaatcgttt
    30901 acggtgcttt tgagcaaatc aaagaagcta ctggcaacga tgcacttgaa gtatttgaaa
    30961 cagctatgga aaacatcatg cctgtacttg aagtacgtgc acgtcgtgtt ggtggttcta
    31021 actaccaagt cccagttgaa gttcgtccag aacgtcgtac aacacttgga cttcgttggt
    31081 tggtaacaat cgctcgtctt cgtggtgaac acacaatgca agaccgtctt gcaaaagaaa
    31141 tcttggatgc tgctaacaac actggtgcag cagttaagaa acgtgaagat actcaccgta
    31201 tggctgaagc taaccgtgca ttcgcacact tccgttggta agataggatg cgaaagcgtt
    31261 aagaaagtcc cagagaaaat agggaatcga agcaggttgc ggttgcaacc aatgagattc
    31321 atctttttct ccagactttt agcttgagct caactaaatc atgatgctag gcacggaagg
    31381 atgcaaggtg aaaataggaa actgacgcag tattcaacga atacaaggag ttttatcttt
    31441 ttcacgcagc atcccgttcc agctcacatc ggctaactaa ctttagcctg ggttcaaatt
    31501 agctaaatcg attagtatta gctataactc agcttaccat ctcgtaagtt gaaaccaaca
    31561 atagcatgaa aacattgaga acgggtaggt cctgcctatc cgtttttatt aaaatcgtgt
    31621 tataatagaa tagaaatcaa aaataaatag gagaaacaaa cctcatggca cgcgaatttt
    31681 cacttgaaaa aactcgtaat atcggtatca tggctcacgt cgatgccggt aaaacaacaa
    31741 ctactgagcg tattctttac tacactggta aaatccacaa aatcggtgaa actcacgaag
    31801 gtgcgtcaca aatggactgg atggagcaag agcaagaacg tggtatcacg atcacatctg
    31861 ctgcgacaac agctcaatgg aacaaccacc gcgtaaacat catcgacaca ccaggacacg
    31921 tggacttcac aatcgaagta caacgttctc ttcgtgtatt ggatggtgcg gttaccgttc
    31981 ttgactcaca atcaggtgtt gaacctcaaa ctgaaacagt ttggcgtcaa gcaactgagt
    32041 acggagttcc acgtatcgta tttgccaaca aaatggacaa aatcggtgct gacttccttt
    32101 actctgtaag cacacttcac gatcgtcttc aagcaaatgc acacccaatc caattgccaa
    32161 tcggttctga agatgacttc cgtggtatca ttgacttgat caagatgaaa gctgaaatct
    32221 atactaacga ccttggtacg gatatccttg aagaagacat cccagctgaa taccttgacc
    32281 aagctcaaga ataccgtgaa aaattgattg aagcagttgc tgaaactgac gaagaattga
    32341 tgatgaaata cctcgaaggt gaagaaatca ctaacgaaga attgaaagct ggtatccgta
    32401 aagcgactat caacgttgaa ttcttcccag tattgtgtgg ttcagccttc aaaaacaaag
    32461 gtgttcaatt gatgcttgat gcggttatcg actaccttcc aagtccactt gacatcccag
    32521 caatcaaagg tattaaccca gatacagacg ctgaagaaac tcgtccagca tctgacgaag
    32581 agccatttgc agctcttgcc ttcaagatca tgactgaccc attcgtaggt cgtttgacat
    32641 tcttccgtgt ttactcaggt gttcttcaat caggttcata cgtattgaat acttctaaag
    32701 gtaaacgtga acgtatcgga cgtatccttc aaatgcacgc taacagccgt caagaaatcg
    32761 acactgttta ctcaggtgat atcgctgctg ccgttggttt gaaagatact acaactggtg
    32821 actcattgac agatgaaaaa gctaaaatca tccttgagtc aatcaacgtt ccagaaccag
    32881 ttatccaatt gatggttgag ccaaaatcta aagctgacca agacaagatg ggtatcgccc
    32941 ttcaaaaatt ggctgaagaa gatccaacat tccgcgttga aacaaacgtt gaaactggtg
    33001 aaacagttat ctcaggtatg ggtgaacttc accttgacgt ccttgttgat cgtatgcgtc
    33061 gtgagttcaa agttgaagcg aacgtaggtg ctcctcaagt atcttaccgt gaaacattcc
    33121 gcgcttctac tcaagcacgt ggattcttca aacgtcagtc tggtggtaaa ggtcaattcg
    33181 gtgatgtgtg gattgaattt actccaaacg aagaaggtaa aggattcgaa ttcgaaaacg
    33241 caatcgtcgg tggtgtggtt cctcgtgaat ttatcccagc ggttgaaaaa ggtttggtag
    33301 aatctatggc taacggtgtt cttgcaggtt acccaatggt tgacgttaaa gctaagcttt
    33361 atgatggttc atatcacgat gtcgactcat ctgaaactgc cttcaagatt gcggcttcac
    33421 tttcccttaa agaagctgct aaatcagcac aaccagctat ccttgaacca atgatgcttg
    33481 taacaatcac tgttccagaa gaaaaccttg gtgatgttat gggtcacgta actgctcgtc
    33541 gtggacgtgt agatggtatg gaagcacacg gtaacagcca aatcgttcgt gcttacgttc
    33601 cacttgctga aatgttcggt tacgcaacag ttcttcgttc tgcatctcaa ggacgtggta
    33661 cattcatgat ggtatttgac cactacgaag atgtacctaa gtcagtacaa gaagaaatta
    33721 ttaagaaaaa taaaggtgaa gactaatccg tcctcactct agaaggaagt cacttagtgg
    33781 cttccttttg tctttagaaa atacctctaa atatggtaaa atagtagaag aataatgtga
    33841 ggaaaatgaa tgtcaaatag ttttgaaatt ttgatgaatc aattggggat gcctgctgaa
    33901 atgagacagg ctcctgcttt agcacaggcc aatattgagc gagttgtggt tcataaaatt
    33961 agtaaggtat gggagtttca tttcgtattt tctaatattt taccgattga aatcttttta
    34021 gaattaaaga aaggtttgag cgaagaattt tctaagacag gcaataaagc tgtttttgaa
    34081 attaaggctc ggtctcaaga attttcaaat cagctcttgc agtcctacta tagggaggct
    34141 ttctctgaag gtccatgtgc tagtcaaggt tttaagtccc tttatcaaaa tttgcaagtt
    34201 cgtgctgagg gtaatcagct atttattgaa ggatctgaag cgattgataa ggaacatttt
    34261 aagaagaatc atcttcctaa tttagccaaa caacttgaaa agtttggttt tccaactttt
    34321 aactgtcaag ttgagaagaa tgatgtcctg acccaagagc aggaagaggc ctttcatgct
    34381 gaaaatgagc agattgttca agctgccaat gaggaagcgc tccgtgctat ggaacaactg
    34441 gagcagatgg cacctcctcc agcggaagag aaaccagtct ttgattttca agcgaaaaaa
    34501 gctgcagcta aacccaagct ggataaggcg gagattactc ctatgatcga agtgacgaca
    34561 gaggaaaatc gtctggtatt tgaaggggtt gtttttgatg tggagcaaaa agtgactaga
    34621 acaggtcgtg ttttaatcaa ctttaaaatg acggactata cttcaagttt ttctatgcaa
    34681 aagtgggtta aaaacgagga agaggcccag aagtttgacc tcatcaagaa gaattcttgg
    34741 ctccgagttc gagggaatgt ggagatgaat aacttcacac gcgatttgac tatgaacgta
    34801 caggatctgc aggaagttgt tcactatgag cggaaggatt tgatgccaga aggtgagcgt
    34861 cgggttgagt ttcatgctca tactaacatg tcgactatgg atgctttgcc agaggtcgaa
    34921 gagattgttg caacagctgc taagtgggga cacaaggcgg ttgctatcac agaccatggg
    34981 aatgtccagt cctttccaca tggctataag gcggctaaga aagcgggaat ccagctgatc
    35041 tatgggatag aagccaatat cgtggaggac cgtgtcccta tcgtctataa cgaagtggag
    35101 atggacttat cagaagcaac ctacgtggtc tttgacgtgg aaacgacggg actttcagct
    35161 atctataatg acttgattca ggttgcggcc tctaagatgt acaaggggaa tgttattgct
    35221 gaatttgatg aatttatcaa tcctgggcat cccttgtcag cttttactac agagttaact
    35281 ggaattacag atgatcatgt caaaaatgcc aaaccactag aacaagtttt gcaagaattc
    35341 caagaatttt gcaaggatac ggtcctagtt gcccacaatg ctgcctttga cgttggcttt
    35401 atgaatgcta attatgagcg tcatggtctt ccaaagatta gtcagccagt tattgatacg
    35461 ctggagtttg ctagaaacct ctatcctgag tataaacgcc atggtttggg gcctttgacc
    35521 aagcgttttg gtgtggcctt ggaacatcac cacatggcca actacgatgc ggaagcgact
    35581 ggtcgtctgc ttttcatctt tatcaaagag gtagcagaaa aacatggtgt gaccgattta
    35641 gctagactca acattgatct aatcagtcca gattcttaca aaaaagctcg gatcaagcat
    35701 gcgaccatct atgtcaagaa tcaggtaggt ctaaaaaata tctttaagct ggtttccttg
    35761 tctaatacca agtattttga aggagtgcca cggattccga gaacggttct agatgcccat
    35821 cgagagggct tgattttagg ttcagcctgt tcagagggtg aagtttttga cgtggtcgtt
    35881 tctcaaggtg tggatgcggc ggttgaggtg gccaagtatt atgactttat cgaggtcatg
    35941 ccaccggcta tctatgcgcc cttgattgct aaagagcagg tcaaggatat ggaggaactc
    36001 cagaccatta tcaagagttt gatagaggtt ggagaccgcc ttggcaagcc tgttttggct
    36061 acgggaaatg ttcactatat cgaaccggaa gaagagattt atcgtgaaat tatcgtccgt
    36121 agtttgggac agggtgcgat gattaaccga actatcggtc atggtgaaca tgcccaacca
    36181 gcaccacttc caaaggctca ttttcgaacg actaatgaga tgttggatga atttgccttt
    36241 ttgggagagg aactggctcg taaactggtt attgaaaaca ccaatgcctt ggcagaaata
    36301 tttgaacccg ttgaagtcgt taagggtgac ttgtatacgc ctttcatcga caaggctgaa
    36361 gaaacagttg ctgagttgac ctataagaaa gcttttgaga tttatggaaa tccgctgcca
    36421 gatattgttg atttgcggat tgaaaaagaa ttaacatcca tactggggaa tggatttgct
    36481 gtgatttatc tggcatcgca gatgctggtg caacgttcta atgaacgggg ttatttggtt
    36541 ggttctcgtg ggtctgtcgg atctagtttc gttgcgacca tgattggaat tacggaggtc
    36601 aatcctctct ctcctcacta tgtctgtggt cagtgtcagt acagtgagtt tatcacagat
    36661 ggttcgtacg gttcaggatt tgatatgccc cataaggact gtccaaactg tggtcacaaa
    36721 ctcagtaaaa acggacagga tattccgttt gagaccttcc ttggttttga tggggataag
    36781 gttcctgata ttgacttgaa cttctcggga gaagatcagc ctagcgccca cttggatgtg
    36841 cgtgatatct ttggtgaaga atatgccttc cgtgcgggaa cagttggtac ggtagctgcc
    36901 aagactgcct atggatttgt caagggttac gagcgagatt atggcaagtt ttatcgtgat
    36961 gcagaagtag aacgcctcgc tcaaggagcg gcgggtgtca agcggacaac aggccaacac
    37021 ccggggggaa tcgttgttat tccgaactac atggatgtct acgattttac gcctgtccag
    37081 tatccagcag atgatgtcac ggctgaatgg cagaccactc actttaactt ccacgatatc
    37141 gatgagaacg tcctcaaact cgatgtactg ggacatgatg atccgaccat gattcgaaaa
    37201 cttcaggatt tgtctggtat tgaccctaat aaaattccta tggatgacga aggcgtgatg
    37261 gcactctttt ctgggactga tgtgctaggg gtaacacctg aacaaattgg aacgcctacg
    37321 ggtatgttgg ggattccaga gtttggaaca aatttcgtac gtggaatggt agacgaaacc
    37381 catccgacaa cctttgcgga attgcttcag ctgtctggtc tgtcccacgg tactgatgtt
    37441 tggttgggga atgctcagga tctgattaag caaggaatag cggacctatc gactgttatc
    37501 ggttgtcggg acgacatcat ggtttacctc atgcatgcgg gtctggaacc taagatggcc
    37561 tttaccatta tggaacgggt acgtaagggt ttgtggctaa agatttcaga agaggagaga
    37621 aatggctata tcgaagcaat gaaggctaat aaggtgccag agtggtatat cgaatcctgt
    37681 gggaaaatta agtacatgtt ccctaaggcc catgcggcag cctacgttat gatggccttg
    37741 cgtgtagctt acttcaaggt tcaccatcct atttattact actgtgctta cttctccatt
    37801 cgtgctaagg cttttgatat caagaccatg ggtgcgggct tggaggtcat caagcgcaga
    37861 atggaagaaa tctctgaaaa acggaagaac aatgaagcct ctaatgtgga aatcgatctc
    37921 tatacaactc ttgagattgt caatgagatg tgggaacgag gtttcaagtt tggtaaatta
    37981 gatctctacc gtagtcaggc gacagagttc ctcatcgacg gggataccct tatcccacca
    38041 tttgtagcaa tggatggtct gggagagaac gttgccaagc aactggtgcg ggcgcgtgaa
    38101 gagggagaat tcctctctaa aacagaacta cgcaagcgtg gtggactctc atcaaccttg
    38161 gttgaaaaga tggatgagat gggtattctt ggaaatatgc cagaggataa ccagttgagt
    38221 ttgtttgatg agttgtttta aaaaattgct taataatcta ttaaaagagg ctaacgtata
    38281 tccaatagat ttacattagc tttctttttt gttaaaatag tctatggaaa gagggtgaga
    38341 gtatgtcaaa gatgagtata agcatccgtc tggatagtga ggttaaggag caggcccaac
    38401 aggtgtttag taatctggga atggatatga caacagctat taatattttc cttcgtcagg
    38461 caattcaata tcagggatta ccttttgatg ttagactaga cgaaaatcgg aagttgctcc
    38521 aagcgttaac ggatttagac caaaatcgta atatgagcca gtcttttgaa tcagtctcag
    38581 atttgatgga ggacttacgt gcttaagatt cgttatcata aacagtttaa aaaagatttt
    38641 aagttggcta tgaagcgtgg tttgaaggca gaattattag aagaagtttt gaattttctg
    38701 gttcaagaaa aagaacatcc tgccagatat cgtgatcatt cattgacggc atccaagcat
    38761 tttcaaggag ttcgtgaatg ccatacccag ccagattggc ttttggttta taaagtagac
    38821 aagtcggaat tgattttaaa tttgctgagg acaggcagtc acagtgattt attttaatct
    38881 attttaaggg ggttctcatg aaactaagaa tatttgcgga agataagccg gctaagaagg
    38941 tatttgaata tcaattagaa cttgctgatc gtacaattct tctatcgaca gcactcttgt
    39001 caggtgctat tgctttagca ggaatctttt ctgctttgaa agaaaaataa aaatagaaaa
    39061 gagaaaacag aatggtttta ccaaatttta aagaaaatct agaaaaatat gcgaaattgt
    39121 tggttgcgaa cggaattaac gtgcaacctg gtcacacttt ggctctctct attgatgtgg
    39181 agcaacgtga attggcacat ctaatcgtga aagaagctta tgccttgggt gcgcatgagg
    39241 tcatcgttca gtggacagat gatgtgatta accgtgagaa attcctccat gccccgatgg
    39301 agcgtttgga caatgtgcca gaatacaaga ttgctgagat gaactatctt ttggagaaca
    39361 aggctagccg tcttggggtt cgttcatctg atccaggtgc cttgaacgga gtggacgctg
    39421 acaagctttc agcttctgct aaagctatgg gacttgccat gaagcctatg cgtatcgcaa
    39481 ctcaatctaa caaggttagc tggactgtag cagccgctgc tggacttgag tgggctaaga
    39541 aagtcttccc aaatgctgcg agcgacgaag aagcagttga tttcctttgg gatcaaatct
    39601 tcaaaacttg tcgtgtctac gaagcagatc ctgttaaggc ttgggaggaa catgcagcca
    39661 ttctcaagag caaggccgat atgcttaata aggagcaatt ttcagccctt cactacacag
    39721 cgccaggaac agatttaaca cttggtttgc caaagaacca cgtttgggaa tcagctggtg
    39781 ctgtcaatgc acagggcgaa gaattcttgc caaatatgcc gacagaagag gtcttcacag
    39841 cgcctgactt ccgtcgtgca gatggttatg tcacttctac aaaaccgctt agctacaacg
    39901 gaaatatcat tgaaggcatt aaggtgacct ttaaggatgg acaaatcgta gatatcactg
    39961 ctgagaaggg tgatcaggtt atgaaagacc ttgtctttga aaatgcgggt gcgcgtgcct
    40021 tgggtgaatg tgccttggta ccagatccaa gtccaatttc tcagtcaggc attacctttt
    40081 ttaacaccct tttcgatgaa aatgcgtcaa accacttggc tatcggtgca gcctatgcga
    40141 ctagcgttgt tgatggagcg gagatgagcg aagaggagct tgaagctgca gggcttaacc
    40201 gttcagatgt tcacgtagac tttatgattg gttctaacca aatggatatc gatggtattc
    40261 gtgaggatgg aacgcgggta cctcttttcc gtaatgggaa ttgggcaaat taaggagata
    40321 atatgttagg aagtatgttc gttggtctcc tagtgggatt tttagcaggt gctatgacca
    40381 atcgtggaga gcgaatggga tgttttggaa aaatgtttct cggttggatc ggagcctttc
    40441 taggtcactt gctctttgga acttgggggc cagttttatc aggaacagct attatcccag
    40501 cgattttagg agccatgatt gttttagcta ttttttggag acgaggaagt taatttccta
    40561 aatctgatac tcaatgaaaa tcaaagagca aactaggaaa ctagccgcag gttgctcaaa
    40621 gcactgcttt gaggttgcag atagaactga cgaagtcagc taaaaacact gctttgaggt
    40681 tgcagataga actgacgaag tcagctaaaa acactgtttt gaggttgcag atagaactga
    40741 cgaagtcagc taaaaacact gttttgaggt tgcagataga actgacgaag tcagtaacat
    40801 atatacggca aggcgacgtt gacgcggttt gaagagattt ttgaagagta tgaaacgaaa
    40861 aggaggttgg tcattgtact agcctccttt tgatatgata taatagttct atgagattag
    40921 ataaattttt agttgcctgt gcggtgggaa gtcggactga ggtcaaaaac ttgctcaagg
    40981 ctgggcgcgt gactgtaaat ggtaaaaaag aaaaatcagc taaattgcag attgatgaaa
    41041 aaatagatga gattcgcttt gatgggcaag tgttggagta tgaagagttt gtctactaca
    41101 tgatgaacaa gcccaaagga gttatctcag cgactgagga tcccaagcac agaaccgttc
    41161 tggacttgtt ggatgacttg gcgcggagta aggaagtttt tccagtagga cgcttggata
    41221 ttgacacgca tggtcttttg ctcttgacca ataatggtca gctggctcat gttcttcttt
    41281 cgcccaagcg tcatgtggac aagacttatc aggctcaggt caagggaatt atgacccaag
    41341 aagatgtgga gacatttatc aagggcattc cgctcaaaga ctttacctgt cagcccgcta
    41401 gactggagat tctttccaca gatgcagaaa agaatcagag ccaaatccgt gtgaccattg
    41461 cagaagggaa gtttcatcag atcaagcgta tggtgggcta ctgtggcaag gaagtggtgg
    41521 acttgcaacg attgactatg ggaactttag tattagatga gaacctggaa cgaggggaat
    41581 ggcgtcgctt gaccaaggaa gaattagaaa ttctccgcgc taatattatt taatttagt
//
LOCUS       DAVLBE010000012        41615 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.012, whole genome shotgun sequence.
ACCESSION   DAVLBE010000012 DAVLBE010000000
VERSION     DAVLBE010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 41615)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41615)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41615
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.012"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            444..1919
                     /locus_tag="VXB91_000678"
     CDS             444..1919
                     /locus_tag="VXB91_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HEV0470174.1"
                     /translation="MKELDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTGKLPISAMDAG
                     ADMAAVSMHKSGGSLTQSSLLLIGEQMNSEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEKVIELSEYARREINAIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSERKSLTLDESVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ"
     gene            complement(1885..2600)
                     /locus_tag="VXB91_000679"
                     /pseudo
     CDS             complement(1885..2600)
                     /locus_tag="VXB91_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809094.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            2856..3716
                     /gene="speE"
                     /locus_tag="VXB91_000680"
     CDS             2856..3716
                     /gene="speE"
                     /locus_tag="VXB91_000680"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HEV0470175.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEDDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQAFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTEYYTANLHVGSFMLPKYVE
                     DILEEEEGKK"
     gene            3713..4972
                     /locus_tag="VXB91_000681"
     CDS             3713..4972
                     /locus_tag="VXB91_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HEV0470176.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVIALIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVEKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMVD"
     gene            4972..6099
                     /gene="nspC"
                     /locus_tag="VXB91_000682"
     CDS             4972..6099
                     /gene="nspC"
                     /locus_tag="VXB91_000682"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HEV0470177.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEAGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDEDMEELLGITDHIVF
                     NSERQLRKHGARCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGADDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPPLRNGFESQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            6096..7181
                     /gene="aguA"
                     /locus_tag="VXB91_000683"
     CDS             6096..7181
                     /gene="aguA"
                     /locus_tag="VXB91_000683"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HEV0470178.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKAAKRAF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALERPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVV
                     AFVGPAEVVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEERYAGERLAASYVNFYIANKAVLVPQFEDVNDQVALDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            7191..8066
                     /gene="aguB"
                     /locus_tag="VXB91_000684"
     CDS             7191..8066
                     /gene="aguB"
                     /locus_tag="VXB91_000684"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HEV0470179.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKVIAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGGVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYDLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(8247..9056)
                     /locus_tag="VXB91_000685"
     CDS             complement(8247..9056)
                     /locus_tag="VXB91_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV0470180.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHITAIHKAIEKGVKLVLCTGR
                     PLFGVLPYYKKLELDLQNEYIIVNNGCSTHQTSDWSLVDWKELSPADIEYLYDLAEKS
                     DVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKFRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL"
     gene            9328..9549
                     /locus_tag="VXB91_000686"
     CDS             9328..9549
                     /locus_tag="VXB91_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0924 family bacteriocin-like peptide"
                     /protein_id="HEV0470181.1"
                     /translation="MILMTKNINLTNEELELIQGGADSYGKNPNGRYDWEIEPVLTLP
                     VHGFCSRGTYDLGYIGGGNHLCKGSAARF"
     gene            9603..10274
                     /locus_tag="VXB91_000687"
     CDS             9603..10274
                     /locus_tag="VXB91_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0470182.1"
                     /translation="MKKRAIQILLALSLIFYKSTWFWRVFNHLAKPYLPASREFFQIL
                     LLMESGVLFLAVIYLLVFAGKKIFHFKWQLRYFIYLLLGYIISYMSDFLFSYFISLSS
                     NQISLNETIEMMGRQEFPYFLLIVCFIAPIAEELIYRGVLMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNLYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(10326..10523)
                     /locus_tag="VXB91_000688"
     CDS             complement(10326..10523)
                     /locus_tag="VXB91_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0470183.1"
                     /translation="MFIFYPQLLYLFIIPYFRSFPKRKKEHPILLNYLHYLPFSRQSY
                     FQNQFKKISGYTPLQYRKEKR"
     gene            10516..11424
                     /locus_tag="VXB91_000689"
     CDS             10516..11424
                     /locus_tag="VXB91_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEV0470184.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKAQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLCEGHPLAQKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            11421..11882
                     /locus_tag="VXB91_000690"
     CDS             11421..11882
                     /locus_tag="VXB91_000690"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEV0470185.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMVLGLTLIIAGGLG
                     NFIDRVSQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGN"
     gene            11872..12759
                     /locus_tag="VXB91_000691"
     CDS             11872..12759
                     /locus_tag="VXB91_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEV0470186.1"
                     /translation="MEIKIETGGLRLDKALSDLSELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLPLEIVYQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLVLAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHSVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            12762..14645
                     /gene="cbpE"
                     /locus_tag="VXB91_000692"
                     /gene_synonym="pce"
     CDS             12762..14645
                     /gene="cbpE"
                     /locus_tag="VXB91_000692"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HEV0470187.1"
                     /translation="MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWREGIETSYKHVLTDRVFRRLKELGVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDSRITNSERLWDNLYGYDKVLQT
                     AAEKGVSVIQNITQGDAHFQFGDMDIQLYNYENETDSSGELKKIWDDNSNSLISVVKV
                     NGKKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQ
                     TSDSLPWKNGVDSEYVNWLKERGIERINAASKDYDATVFDIRQDGLVNISTSYKPIPS
                     FQAGWHKSSYGNWWYQAPDSTGEYAVGWNEIKGEWYYFNQTGILLQNQWKKWNNRWFY
                     LTDSGVAAKNWKKIAGIWYYFNKENQMEIGWIQDKEQWYYLDVDGSMKTGWLQYKGQW
                     YYFAPSGEMKTGWVKDKEAWYYMDSTGIMKTGEIEVAGHHYYLEESGAMKQGWLKKAN
                     DWYFYKTDGSRAIGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVPIEKS
                     ATIKTTSHSEIKESKEVVKKDLENKETSQHESVTNSSTSQDLTSSTSQSSETSVNKSE
                     SEQ"
     gene            14725..15855
                     /locus_tag="VXB91_000693"
     CDS             14725..15855
                     /locus_tag="VXB91_000693"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004240022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HEV0470188.1"
                     /translation="MNNRSETMKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAML
                     HEAGHELILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQI
                     VSAQILLTQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDELKVGDNDTLSA
                     QVAAMVQADLLVFLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTG
                     GMLTKIKAATIATESGVPVYICSSLKSDSMIEAAEETEDGSYFVAQEKGLRTQKQWLA
                     FYAQSQGSIWVDKGAAEALSQHGKSLLLSGIVEAEGVFSYGDIVTVFDKESGKSLGKG
                     RVQFGASALEDMLRSQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            15865..17127
                     /locus_tag="VXB91_000694"
     CDS             15865..17127
                     /locus_tag="VXB91_000694"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HEV0470189.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLEN
                     GLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSRESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHENKAASILPRLDQ
                     MLVADRKEAGLEPIQFRLDSKASQFVSGQAAQAQDFDTEFLDYILAVKVVSSLEEAVA
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHTRGPMGLKELTSYKYVVAGDGQIRE"
     gene            17131..17928
                     /gene="proC"
                     /locus_tag="VXB91_000695"
     CDS             17131..17928
                     /gene="proC"
                     /locus_tag="VXB91_000695"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HEV0470190.1"
                     /translation="MKIGFIGLGNMGASLAKSVLQTRTSDEILLANRSQAKVDAFIAD
                     FGGQASSNEEMFAEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLTLEKL
                     ASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSEIFCQLLAKAGLLVELGES
                     LINAATGLAGCGPAFVYLFIEALADAGVQTGLPRETALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEAHAFRGIVMEAVHQAYKRTQELGK"
     gene            18044..18682
                     /locus_tag="VXB91_000696"
     CDS             18044..18682
                     /locus_tag="VXB91_000696"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HEV0470191.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILEEKGVEVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLDLHKKVRQGYLSLLDKEGNRIVKIDASLPLEQVVETTNAVLFDGMGLAK"
     gene            18679..19569
                     /locus_tag="VXB91_000697"
     CDS             18679..19569
                     /locus_tag="VXB91_000697"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HEV0470192.1"
                     /translation="MKQDQLKAWQPAQFDRFVRILEQDQLNHAYLFSGFFGSLEMAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQEEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLAKFSQSRAEAEKLAHQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            19609..19926
                     /gene="yabA"
                     /locus_tag="VXB91_000698"
     CDS             19609..19926
                     /gene="yabA"
                     /locus_tag="VXB91_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HEV0470193.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            19929..20798
                     /gene="rsmI"
                     /locus_tag="VXB91_000699"
     CDS             19929..20798
                     /gene="rsmI"
                     /locus_tag="VXB91_000699"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HEV0470194.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGASAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFGL
                     KKDYPETQIFYESPHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     AETPLKGECLLIVEGASQGVEEKDEEDLFVEIQTRIQQGMKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEEKQ"
     gene            21025..21543
                     /locus_tag="VXB91_000700"
     CDS             21025..21543
                     /locus_tag="VXB91_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HEV0470195.1"
                     /translation="MRTYENKEELKAEIEKTFEKYILEFDNIPENLKDKRADEVDRTP
                     AENLAYQVGWTNLVLKWEEDERKGLQVKTPSDKFKWNQLGELYQWFTDTYAHLSLQEL
                     KAKLNENINSISAMIDSLSEEELFEPHMRKWADEATKTATWEVYKFIHVNTVAPFGTF
                     RTKIRKWKKIVL"
     gene            21652..22300
                     /locus_tag="VXB91_000701"
                     /pseudo
     CDS             21652..22300
                     /locus_tag="VXB91_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345255.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
     gene            complement(22289..23092)
                     /locus_tag="VXB91_000702"
                     /pseudo
     CDS             complement(22289..23092)
                     /locus_tag="VXB91_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            23087..23341
                     /locus_tag="VXB91_000703"
     CDS             23087..23341
                     /locus_tag="VXB91_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEV0470196.1"
                     /translation="MHRTTIPYFVSQEVYWKVRNIEAEAIRRNCERGAIFSGKIKYHE
                     DSQFKGDHYVECYAVLDNTVIARDRITVPIDPLCGKDFIE"
     gene            23587..24921
                     /gene="trmFO"
                     /locus_tag="VXB91_000704"
     CDS             23587..24921
                     /gene="trmFO"
                     /locus_tag="VXB91_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HEV0470197.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVANHPLIEVVRDEITELPTDVITVIATGPLTSDALAEKIHALNDGDGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEVIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
     gene            25005..25742
                     /locus_tag="VXB91_000705"
     CDS             25005..25742
                     /locus_tag="VXB91_000705"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HEV0470198.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQSGNIKRVVFGENIGTTVSNNIEEKE"
     gene            25751..26308
                     /gene="frr"
                     /locus_tag="VXB91_000706"
     CDS             25751..26308
                     /gene="frr"
                     /locus_tag="VXB91_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HEV0470199.1"
                     /translation="MANVIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRVHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            26368..27222
                     /gene="cvfB"
                     /locus_tag="VXB91_000707"
     CDS             26368..27222
                     /gene="cvfB"
                     /locus_tag="VXB91_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HEV0470200.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTTLEVTATQDQFGWGRVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPELKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            27231..27446
                     /locus_tag="VXB91_000708"
     CDS             27231..27446
                     /locus_tag="VXB91_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HEV0470201.1"
                     /translation="MRKSFYTWLMTERNPKSNSPKAILADLAFEEAAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDSIWQEYLEH"
     gene            27532..28500
                     /locus_tag="VXB91_000709"
     CDS             27532..28500
                     /locus_tag="VXB91_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HEV0470202.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMVLVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQEKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD"
     gene            complement(28478..28657)
                     /locus_tag="VXB91_000710"
     CDS             complement(28478..28657)
                     /locus_tag="VXB91_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0470203.1"
                     /translation="MTQEDALIVISHIKVLSIVPNRCLKPLDKTFSLYNWIFLSQKYI
                     LLQANFLKISRVQLQ"
     gene            28693..29193
                     /locus_tag="VXB91_000711"
     CDS             28693..29193
                     /locus_tag="VXB91_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0470204.1"
                     /translation="MIDQLSKYYSCRILTEKDIPSILSLYESNPLYFQHCPPEPNFAT
                     VKEDMLCLPEGKAKADKFFVGFWNGSDLVAVIDFVYAHPDEETVFIGLFMVDQAYQRK
                     GIGSHIVTEALAYFAKNFRKARLAYVKGNPQSQHFWEKQGFKSIGCEVKQELYTVVIA
                     EQSLED"
     gene            29196..29456
                     /locus_tag="VXB91_000712"
                     /pseudo
     CDS             29196..29456
                     /locus_tag="VXB91_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003069408.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
     gene            complement(29823..30149)
                     /locus_tag="VXB91_000713"
     CDS             complement(29823..30149)
                     /locus_tag="VXB91_000713"
                     /inference="COORDINATES: protein motif:HMM:NF013430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0470205.1"
                     /translation="MVDVAVDQGGVIETADRVTTHDEPVYEKHGVLHYAVANIPGAVA
                     RTSTIALTNVTLPYIEALAGKGFAQAISEDEGLRQGVTTYQGYLTSLPVAQGLNRDYT
                     DINDLV"
     gene            complement(30095..30508)
                     /locus_tag="VXB91_000714"
     CDS             complement(30095..30508)
                     /locus_tag="VXB91_000714"
                     /inference="COORDINATES: protein motif:HMM:NF013430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-binding protein"
                     /protein_id="HEV0470206.1"
                     /translation="MGAHFLTKQAGGSGVLPGGVPGVPKGKVTIIGDGVVGTHAARIA
                     LGLGAQVTILDISAKRLSVLEEVFGSQIQTLISNSFNIEASMRDADVVIGAILIPGAK
                     APELVTDEMVKQMRPGSVSLTLLLTKVALSKQLTV"
     gene            complement(30509..30934)
                     /locus_tag="VXB91_000715"
     CDS             complement(30509..30934)
                     /locus_tag="VXB91_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
                     /protein_id="HEV0470207.1"
                     /translation="MLIGIPKEIKNNENRVALTPAGVHSLVSRGHRVLIETNAGLGSG
                     FTDADYQKQGAEIVATAGEAWAAELVVKVKEPLSSEYGYLRDDLLLFTYLHMAAAPEL
                     ADAMLAAKTTGIAYETVRDNQGQLPLLVPMSEVAGRMAV"
     gene            31111..31680
                     /locus_tag="VXB91_000716"
     CDS             31111..31680
                     /locus_tag="VXB91_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0470208.1"
                     /translation="MESIFVKFAQYPSIETERLLLRPVTLDDAEAMFDYASDKGNTRY
                     TFPTNQSLEETKNNIAQFYLANPLGRWGIELKDNGKFIGTIDLHKIDPVLKKAAIGYI
                     INKKYWNQGLTPETNRAVIELAFEKIGMNKLVALYDKDNSASGKVMEKSGMRFSHAEP
                     YACMDQHEKGRIVTRVHYVLTKEDYFANK"
     gene            31748..32398
                     /locus_tag="VXB91_000717"
     CDS             31748..32398
                     /locus_tag="VXB91_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEA family DNA-binding protein"
                     /protein_id="HEV0470209.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQ
                     AEVAAVSKDLVSEKEVNKEEKEEPLEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSISKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGGKTIEKLKDYVTVD"
     gene            32382..34622
                     /locus_tag="VXB91_000718"
     CDS             32382..34622
                     /locus_tag="VXB91_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HEV0470210.1"
                     /translation="MLQWIKNFSIPLIYLSFLLLWLYYAIFSASYLALLGFVFLLVCL
                     FIQFPWKSAGKVLIICGIFGFWFVFQNWQQSQASQNLADSVERVRILPDTIKVNGDSL
                     SFRGKSNGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAY
                     LKTQGIYQTLNIKTIQSLQKIGSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLL
                     GHLDTDFEEMNELYSSLGIIHLFALSGMQVGFFMNGFKKLLLRLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIVMPNFFLTAGGVLSC
                     AYAFILTMTSKEGEGLKAVTSESLVISLGILPILSFYFAEFQPLSILLTFVFSFLFDL
                     TFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVTSRPLVFGQPNAWFLILLLI
                     SLALVYDLRKNIKKLTVLCLLITGLFLLTKHPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESYKKIEKWQEKMTTSNAQRTLIPYLKSRGVAKIDQLILTNTDKEHVGDL
                     SEVTKAFHVGEILVSKDSLKQKEFVAELQATQTKVRSMTVGENLPIFGSQLEVLSPRK
                     MGDGGHDDTLVLYGKFLDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQHGNKKSS
                     SPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINSKVYRTDQQGAIRFKGLDSW
                     KIESVR"
     gene            34764..34988
                     /locus_tag="VXB91_000719"
     CDS             34764..34988
                     /locus_tag="VXB91_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0470211.1"
                     /translation="MIIGLFQSSISAVTVTKSYKYDWNTVWEYSTNYHDHQYAWIPSW
                     SRYDSYSEYPVGSGWNYGRYEIINYYSGGY"
     gene            35021..35608
                     /locus_tag="VXB91_000720"
     CDS             35021..35608
                     /locus_tag="VXB91_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0470212.1"
                     /translation="MLQLTHVTLKTRQVILQDVDFTFKKGRVYGLLAINGSGKTTLFR
                     AISNLIPISSGNIAAPPSLFYYESIEWLDGNLSGMDYLRLIKNIWKSGLNLRDEIAYW
                     EMSDYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDVCDRVVTIHQGQIEEV"
     gene            35612..36793
                     /locus_tag="VXB91_000721"
     CDS             35612..36793
                     /locus_tag="VXB91_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0470213.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIVLALFVSVLGVTFYLNSQTANSHS
                     LESRLESRIAANERAINENEEKLSQMSDTSSEEYQFAKNNLDVQKNLLTRKTEILTLL
                     KEGRWKEAYYLQWQDEEKNYEFVSNDPTASSGLKMGVDRERKIYQALYPLNIKAHTLE
                     FPTHGIDQIVWILEVIIPSLFVVAIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAISS
                     LGVGVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYPIYSLVNQEVTIGKMQDVLFPG
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQKIAHLIPF
                     TYLRSVEILSGRLPKQIDNVDLNWSMGMVLLPCLIILLLVGILFIERWGSSRKKEVFK
                     V"
     misc_feature    36953..37084
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            37100..37630
                     /gene="infC"
                     /locus_tag="VXB91_000722"
     CDS             37100..37630
                     /gene="infC"
                     /locus_tag="VXB91_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HEV0470214.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     gene            37663..37863
                     /gene="rpmI"
                     /locus_tag="VXB91_000723"
     CDS             37663..37863
                     /gene="rpmI"
                     /locus_tag="VXB91_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HEV0470215.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            37915..38274
                     /gene="rplT"
                     /locus_tag="VXB91_000724"
     CDS             37915..38274
                     /gene="rplT"
                     /locus_tag="VXB91_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HEV0470216.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            38332..38712
                     /locus_tag="VXB91_000725"
     CDS             38332..38712
                     /locus_tag="VXB91_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV0470217.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            38962..39762
                     /locus_tag="VXB91_000726"
     CDS             38962..39762
                     /locus_tag="VXB91_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HEV0470218.1"
                     /translation="MNLTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHERGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPESETVSQRVCEDGPVFRTGTVVL"
     gene            39773..40711
                     /locus_tag="VXB91_000727"
     CDS             39773..40711
                     /locus_tag="VXB91_000727"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HEV0470219.1"
                     /translation="MTTNRLQVSLPGLDLKNPIIPASGCFGFGQEYAKYYDLDLLGSI
                     MIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAEKLPWLEREYPNLPIIA
                     NVAGFSKQEYAAVSHGISKVTNVKAIELNISCPNVDHCNHGLLIGQDPDLAYDVVKAA
                     VEASEVPVYVKLTPSVTDIVTVAKAAEDAGASGLTMINTLVGMRFDLKTRKPILANGT
                     GGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEMYLAGASAIGVGTANFT
                     NPYACPDIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            40753..>41615
                     /gene="lytB"
                     /locus_tag="VXB91_000728"
     CDS             40753..>41615
                     /gene="lytB"
                     /locus_tag="VXB91_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HEV0470220.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASD
                     GTWQGKQYLKEDGSQAANEWVFDTHYQSWFYIKADANYAENEWLKQGDDYFYLKSGGY
                     MAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKA
                     DGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFY
                     IKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYLKFDGKIAEKEWVYDS
                     HSQAWYYFKSGG"
BASE COUNT        12504 a         7539 c         9474 g        12098 t
ORIGIN      
        1 tttttatcaa aaaatacttt acaagttctt aaaaacatga tatagtaata aagcttagaa
       61 aatgagatga tgttttctag caaatataaa cccgagtaaa aaatgcctac ggacaggcag
      121 ggttgaatgc cgaagcgtgg ttgaaaagcc acattattga tagggttaaa agcctacttt
      181 tataagttga tgttaggaca cttgtcctaa ttcataaatt tttagtgtgg tgaaagcaca
      241 cgtcatcttg tgaaacgatc aataaagtac gtaatatttg ctactagaga gttaggaaac
      301 atcgggaaca gacatactca acagaaacca aaataaacac gtcagaagat tgcagagcag
      361 gtgaaaacct gctctttttt catgagtcaa cctttagttc cttagttttc ataaggtcct
      421 aaaaatattg aaaggagtat gttttgaaag agttagatca aaaccaagcc ccaatttatg
      481 aggccttggt gaagttacgc aagaaaagga ttgttccctt tgatgttcca ggtcacaagc
      541 gtggacgggg aaatccagaa cttgtcgaac tcttaggaga aaaatgtgta ggcattgatg
      601 tcaattcgat gaaacccttg gataatttag gccatcctat ttcgattatt cgtgatgcag
      661 aggagctggc tgcagatgct tttggagcta gccatgcctt tctaatgatt ggtggaacaa
      721 cttcatcggt gcagactatg attctggcaa cctgcaaggc aggagataag attattctgc
      781 cacgaaatgt ccataaatct gctatcaatg cgttggttct atgtggtgcc attcccatct
      841 atatcgagat gagtgtagat cctaagattg gtatcgcttt aggtcttgaa aatgaccgag
      901 tagcacaggc cataaaggac catccagatg ctaaggctat cctaatcaac aatcctactt
      961 actacggcat ctgttcagac ctaaaggggt tgacagaaat ggctcatgaa gctggcatga
     1021 tggttttagt agatgaagcc catggagcgc atttgcattt cactggtaaa cttccaattt
     1081 ctgctatgga tgcaggagct gatatggcag cagtttccat gcataagtct ggtgggagtt
     1141 tgacacaaag ttcgcttctt ttaatcgggg agcagatgaa ttctgaatac gttcgtcaga
     1201 taattaacct gactcagtct acatctgcct cttacttgtt gatggctagt ttggatattt
     1261 cacgtcgcaa cttggccctt cgtggtaaag agtcgtttga gaaagtcatt gagctatctg
     1321 agtatgcccg ccgtgaaatc aatgctatcg gtggctacta tgcctactca aaagagttaa
     1381 tagacggtgt ttcggtttgc gattttgacg taactaagct gtcagtttac actcagggta
     1441 ttggcttaac aggtatcgag gtttatgacc tcttgcgaga cgaatacgac attcagatcg
     1501 agtttggtga tatcggcaat atcttggcct atatttccat cggcgaccgc atccaagaca
     1561 tcgagcgctt ggttggtgct ctggctgata ttaagagact ctattcaaga gatggaaaag
     1621 atttgatagc aggagaatat attcagcccg agttggtgct gtctccacaa gaagccttct
     1681 attcagagag aaaaagtttg accttagatg agtctgttgg acaggtctgt ggagaatttg
     1741 tcatgtgcta tcctccaggg attcctatct tggctcctgg tgaacgcatt acacgagaaa
     1801 ttgtagacta tatccaattc gccaaggaac gtggttgctc cctccaaggg acggaagatc
     1861 cagaggtcaa tcatatcaac gttattaaga gaaagacaaa ctataagaaa agtcaatagt
     1921 tttatctaaa ctatttctta tttcaatttg atgatttggc gatgatttta gagcacggca
     1981 aaaagccctt gaattagaag cggtcaatcg cttaatttct atcagcttat caaatcctgc
     2041 ctcaatcctt ttctgaggat tagggtagcg tgtcaagagt tggtaggtat attctgaatg
     2101 ctttccaacg attttatcca actcaggaaa gatgatatca agacaacgag tgtattgtac
     2161 tttccaatca gactgttttt cttgagacga tgaatatgtc tagccagtat ttttagttct
     2221 acttgccgat tatcgtgttg aaattgttca cgattggggt cagaaagaag tttaagagcg
     2281 atgccatgag cgtctttctt atccgtttta gtcttgtgaa gtgataatga tttggcaaat
     2341 tccttgatga gcaaaggatt gtaggtgtaa actttatatc cttgttcatg caggaagttc
     2401 agtagattaa aggcataatg tccggtattt tcaagagcga tgagacagtc ttggttgagt
     2461 tgtcgaagag acagatctaa gagttcaaaa ccagctttat tatttgaaaa agtgagtggt
     2521 ttaagaacag tttttcctgg aacattcaag gctgtaacat cgtgtttatt tttagcgaca
     2581 tcaatgccca cataaagcat gggagtacct ccagatgtag tatttcaagt ctacttggtt
     2641 atccacgaat tttttgcctt gttaccttag acgagataaa acgtctatgc gttatcaaac
     2701 tcattaccaa ttgaaacaaa aaactgtggt tagagccttt cggaaatcgt caagcgattg
     2761 gagggaataa actaatccac agtggcttat tccaagtata ccacttgggc tttggcagta
     2821 gctaactgcg ctaaatataa tataaggaga aatagatgga tttatggttt tctgaagttc
     2881 atactccaga tgtcaaattg tctctgagaa cagccaagca actttacgct ggaaaaagtg
     2941 aatggcagga tatcgaagtc ttggatacgc cagcttttgg gaaaatactg attttaaatg
     3001 gccatgtctt gttctcagat gcggatgatt tcgtctacaa tgaaatgacc gttcacgttc
     3061 ccatggctgt ccacccaaat ccaaagaaag tattggttat tgggggtggt gacggcggtg
     3121 ttgcccaagt attaacactc tatcctgaac tggaacaaat cgatatcgtg gaaccggatg
     3181 agatgttggt cgaggtctgt cgtgagtatt tcccagactt tgctgcaggg ctagatgatc
     3241 ctcgtgttac catttactac caaaatgggc tacgcttttt gcgaaactgc gaagatgatt
     3301 acgatattat catcaacgat gcgacagatc catttggcca tacggaagga ctctttacca
     3361 aggaattcta cggcaatagt tatcgagctc tgaaggaaga cggcatcatg atttaccagc
     3421 atgggagtcc cttctttgac gaggatgagt cggcctgccg aagcatgcac cgcaaggtca
     3481 atcaagcctt tccaatcagt cgggtttatc aggcccatat tccaactagc ccagctggct
     3541 attggttgtt tggatttgca tcgaaaaaat accaccctgt caaagatttt gacaaggaag
     3601 gttggaaaaa acgccagctt ttcacagaat actacactgc aaacttacac gtgggatcct
     3661 ttatgttgcc caagtatgtt gaggacattt tagaagaaga ggaaggaaaa aaatgagtcg
     3721 tttactagtt attggttgtg ggggcgttgc ccaagttgct atttcaaaga tttgtcaaga
     3781 tagcgaaaca tttacagaga ttatgattgc tagccgtacc aagtcaaaat gcgatgactt
     3841 gaaagcgaag ctagaaggca aaacaagtac taaaattgaa actgcagcac ttgatgctga
     3901 caaggttgaa gaagtgattg ccctgattga aagctacaaa ccagaagctg ttttgaatgt
     3961 agctctgcct tatcaagatt taaccattat ggatgcttgt ttggcaacag gtgttcacta
     4021 tatcgataca gccaactacg aagcagaaga cacagaagac cctgagtggc gtgctatcta
     4081 cgaaaaacgt tgtaaggaac ttggttttac agcctacttt gactactcat ggcagtgggc
     4141 ttatcaagag aaattcaaag aagcaggctt gactgctctt cttggttctg gttttgaccc
     4201 aggtgtaact agtgtctttt cagcttatgc cctcaaacac tattttgatg aaatccatta
     4261 tatcgacatt ttagactgta atggcggtga ccacggttat ccatttgcaa ccaactttaa
     4321 tccagaaatt aatctccgtg aggtttctgc gccaggttct tactgggaag atgggaaatg
     4381 ggtcgaagtc gaagctatgt ctatcaagcg tgagtatgat ttccctcaag ttggacaaaa
     4441 agatatgtat ctccttcacc atgaagaaat cgaatcattg gccaagaaca ttccaggtgt
     4501 caaacgcatt cgtttcttta tgacttttgg tcaatcttac ttgacgcaca tgaaatgtct
     4561 tgaaaatgtt ggactccttc gtacggatac cattaacttt aacggccaag aaattgttcc
     4621 aattcaattt ttgaaagcct tgcttccaga tcctgctagc cttggcccac gtactgtagg
     4681 taaaaccaat attggatgta tctttacagg tgtcaaagat ggcgttgaaa agactatcta
     4741 catctacaat gtttgcgacc atcaagagtg ctatgcagaa gtcgggtcac aagcaatttc
     4801 atacacgaca ggcgttccag ccatgattgg gacaaaatta gtcatgaacg gaacttggaa
     4861 acaagctgga gtgtataacc ttgaggagtt agatccagat ccattcatgg aagctttgaa
     4921 tgagtatggt ttgccatggg ttgtggttga aaatccacaa atggtggact aatgaagtta
     4981 gaacaagtac caacaccagc ctatgttatt gacttggcca agttagaagc taattgccgc
     5041 attctacaat atgtacaaga agaggccggt tgcaaggtct tgcttgccca gaaggcatat
     5101 tccctctaca aaacttatcc cttgattagc cagtatctat caggtacgac agctagtgga
     5161 ctctatgagg ccaaattggc aagggaagaa tttcctggtg aagtccatgt ttttgcacca
     5221 gctttcaagg atgaggacat ggaggaattg cttgggataa cagaccatat cgtctttaac
     5281 tcagagagac agttgcgtaa gcatggggct cgttgtcgag aggctggtgt cagtgttggt
     5341 ttgcgcctca accctcagtg ttcaactcaa ggagatcacg cgctctatga cccttgtgca
     5401 cctggttctc gctttggagt tactatagac aagattccga gtgatttgct agatttggtt
     5461 gacggacttc attttcatac cctttgcgag cagggagcag atgatttaca aacaactttg
     5521 aaagcagtag aagaacagtt tggtccctac ttacatgagg taaaatggct caatatgggt
     5581 ggtggtcatc atattacaag agaaggttac gatgtggatt tgctgatttc agaaatcaag
     5641 cgtatccgaa aaacttacaa tcttgaaatc tatatcgagc ctggtgaagc cattgcgctt
     5701 aatgcgggtt atttagcaac tgaggtatta gatattgtag aaaacggtat ggaaatcttg
     5761 gttttagacg cctctgcgac ctgccatatg cctgatgtac ttgagatgcc ctatcgtcca
     5821 cctttgagaa atggctttga gtcacaggaa aaagcccata cctacagact ttcttctaat
     5881 acctgtctga ctggcgatgt gattggtgat tatagttttg aaaatccagt ccaaatcgga
     5941 gacagacttt attttcaaga catggccatt tattcttttg tcaaaaataa tacctttaat
     6001 ggtattggat tgccaagtct ctatctcatg gacgaacagg gagactgtag cttactcaaa
     6061 gcttttggct atcaagactt taaagggaga ttatcatgat ggacagtcca aaaaaattag
     6121 gctatcacat gccagcagag tacgaacccc atcatggtac cctcatgata tggccgactc
     6181 gaccaggatc atggcctttt caaggaaagg ctgctaaaag agcatttact cagatcatcg
     6241 agaccatagc agaaggggaa agagtctatc ttttggtgga gcaggcctat ctatctgaag
     6301 cccaatccta tcttggagac aaggttgttt atttagacat tcccaccaat gatgcctggg
     6361 cgcgtgatac tggcccaacc attctcgtca atgataaagg taagaaatta gccgtggatt
     6421 gggcctttaa tgcttgggga ggcacctatg atggtcttta tcaagattat gaagaggatg
     6481 accaagtagc cagtcgtttt gctgaggcct tggaaaggcc tgtctatgat gctaaacctt
     6541 ttgtactgga aggaggcgca atccatagcg atggtcaagg aactattctc gtaactgaaa
     6601 gttgcttgct tagtcctggt cgcaatccta acctgactaa agaggagatt gaaaacacat
     6661 tattagaaag tcttggtgct gaaaaagtta tttggcttcc ttatggtatt tatcaggatg
     6721 aaaccaatga acacgtcgat aatgttgttg cctttgttgg tcctgctgag gttgttttgg
     6781 cttggacaga tgacgaaaat gatccccagt atgccatgtc aaaagcagat ctcgaactct
     6841 tagaacagga aacagatgca aaaggttgtc acttcaccat tcataaattg cctatccctg
     6901 cagttcgaca agttgtgaca gaagaagatt tgccaggcta catctatgaa gaaggagaag
     6961 aagagcgata cgcaggtgaa cgactagcag cttcctacgt aaacttttat atcgccaaca
     7021 aggctgtctt ggttccacag tttgaggatg taaacgacca agtggcctta gatatcctca
     7081 gcaagtgttt cccagaccgt aaagttgtcg gaataccagc cagagatatt ctcttaggtg
     7141 gtggcaatat ccactgtatc acccaacaaa ttccagaata ggagaaaaag atgagaaatg
     7201 taagagttgc aaccattcag atgcaatgcg ctaaggatgt ggcaacaaat atccaaaccg
     7261 cagagcgttt agtacgtcag gctgctgagc aaggagccca aattattctc ttgcccgagt
     7321 tgtttgaaca tccctatttc tgtcaggaac gtcagtatga ctactaccag tatgcccaat
     7381 ctgtagcgga aaatactgcc attcagcatt ttaaggtgat tgctaaggaa ctacaagttg
     7441 ttttaccaat cagtttctat gaaaaagatg gtaatgtctt gtataactct attgccgtca
     7501 ttgatgcaga tgggggagtg ctgggcgttt atcgaaagac ccatatacca gatgaccatt
     7561 attatcaaga aaaattctat ttcacgcctg gtaacactgg tttcaaggtc tggaatactc
     7621 gctatgctaa gattggtatc ggtatctgtt gggatcaatg gttccctgaa acagcccgct
     7681 gtcttgcatt gaatggtgct gaattgctct tttatcctac agctatcggt tcagagccaa
     7741 ttttggatac agatagttgt ggtcactggc aacgtactat gcaagggcac gcagcagcga
     7801 atattgttcc agtcatcgca gccaatcgtt atggtttaga ggaggttact cctagtgagg
     7861 aaaatggcgg acagagttcc agtcttgact tctacggttc ctcctttatg acggatgaaa
     7921 caggagctat tctagaacga gctgaaagac aagaagaagc tgttctgtta gctacttatg
     7981 acctagacaa gggagcaagt gaacgtctaa actggggctt gtttcgagat agaagaccag
     8041 aaatgtatag acaaattaca gattagtgtg ggagaaatga gagattcatt ctgctagact
     8101 aacttcttat tagcaactat aagatactat ggcatctagt aaatcgattt ttatgattcg
     8161 ctattcttgt ctattgatta gtccgtattt taaaatatta gcaaaaaagc aaatagcagt
     8221 aacttctgtc tatttgcttt tcttttttat agaatatatt tctcaatagc acgcgcaacg
     8281 ccgtcttctt cgttgcttga ggtaacggca tccgcaagag atttgacata atcgctggca
     8341 tttcccattg caatcccaag ccctgcaaac tggagcattt cgatatcgtt attagcatcg
     8401 cccatggcca taatctctga ggaatcaatc ttcaaaatct cagctagtcg tgaaagagca
     8461 gtagcctttg tcgttccaag cggcattgct tcataaatga caggctgcga acgaactcca
     8521 ctgaatcgtt ggcaaagctc ttcagcaaaa cgctgctcaa aatcgtctgt ttgttctttt
     8581 gttcctaaaa acataccttg gaacatccgg aactttccac tagtcgcttc ttcaagagaa
     8641 atttcagtca ggtctgaaaa tactagttta gcatcatttt caataacttg attgggtttg
     8701 ccaccgagaa caaaataatg tgactcgtca aaaagtgtca actgaacatc actcttttca
     8761 gcaaggtcat agaggtattc gatgtcagct ggactcagtt ctttccagtc aactagactc
     8821 caatcactgg tctggtgagt tgaacaaccg ttgttaacaa taatatattc gttctggagg
     8881 tcaagctcca gttttttgta gtaggggagg acaccgaaaa gggggcgacc cgtacagaga
     8941 accagtttga cacctttttc aatggctttg tgaatagcag taatgtgagc ttgtgggatt
     9001 tccttggctt cattgaggag ggtgccgtcc atatccaagg ctagtagttt aatcataggt
     9061 cttccttctt tatcttttgc tattattata gcatattttg gagaagaaat tgatagaaag
     9121 cttgagacta attgatttta tagtttaaga tgttttgatg acaattcatg atttgaagag
     9181 gatatttggc aaagatatgc tatactatgt ttgtcaatgt tgcaactaga caaattaaaa
     9241 aaccaactta atataatagt ttttttgtaa gtaggtatga gtatcagatt actcaactaa
     9301 tctgaagaat aatggaggaa atatatcatg attttaatga caaaaaatat aaatctaaca
     9361 aatgaagaat tagagctgat acaaggtgga gcagattcat atggtaaaaa tcctaatggt
     9421 aggtacgatt gggaaataga accagtatta actctgccgg ttcatggatt ttgttccaga
     9481 ggcacctatg atttaggata tattggagga ggcaatcatc tttgcaaagg aagtgctgcg
     9541 agattttaag taaaatttat tagtaatatg aagaaacaag tggagaaagc agagaattta
     9601 atatgaaaaa acgggctatt caaattttac tagcattgtc cttaattttt tacaaatcaa
     9661 cttggttttg gagagttttc aatcacctcg caaagcccta tctaccagca agtcgtgaat
     9721 tttttcagat tctgcttttg atggagagcg gagttctttt cttagcggtc atctatctac
     9781 tggtttttgc aggaaagaaa atttttcatt tcaagtggca gctgaggtac ttcatctacc
     9841 ttttactggg ctacatcatt tcatatatgt ctgacttcct cttttcgtat ttcatatccc
     9901 tgtcttcaaa tcagatttct ttgaatgaaa cgatagaaat gatggggaga caggagttcc
     9961 cttatttctt gctcatcgtt tgcttcatcg cccctattgc tgaggaattg atttatcgag
    10021 gtgtgcttat gacaaccttt ttcaaaaact caccttggta cggagatgtt ttgctttctg
    10081 ctattatttt cggttatatt catatcaatt ttgctttaac tcctcttgct tttttcattt
    10141 atgctagtgg aggtctgatt ttagctctat tgtatcgcat gactaaaaat ctctactatc
    10201 caatactagt tcatattctc atcaatatca ctgccttctg ggatgtttgg ttactcctat
    10261 tttcaggaag ttagcttact aaaaaaatgt cggaattttc cggcattttc ttttttcaca
    10321 aatagtcaac gtttttcttt ccgatactga agtggtgtgt agccacttat ttttttgaat
    10381 tgattttgaa aataagattg gcgtgagaaa ggcagatagt gaagatagtt aagaagaata
    10441 ggatgttctt ttttcctttt tggaaaactt ctaaaatatg gtataatgaa aagataaaga
    10501 agttgggggt agaagatgaa cattcaacaa ttacgctatg ttgtggctat tgccaatagt
    10561 ggtacttttc gtgaagctgc tgaaaagatg tatgttagtc agccgagtct gtctatttct
    10621 gttcgtgatt tggaaaaaga gttgggcttt aagattttcc gtcggaccag ctcagggact
    10681 ttcttgaccc gtcgtgggat ggaattttat gaaaaagcgc aagaattggt taaaggattt
    10741 gatatttttc aaaatcagta tgccaatcct gaagaagaaa aagatgaatt ttccgttgct
    10801 agccagcact atgacttctt accaccaact attacggcct tttcagagcg ctatcctgac
    10861 tataagaact tccgtatttt tgaatcaact actgttcaaa tattagatga agtggcgcaa
    10921 gggcatagtg agattgggat tatctacctc aacaatcaaa ataaaaaggg gattatgcaa
    10981 cgggttgaaa agttaggtct ggaggtcatc gaattgattc ctttccatac ccatatttat
    11041 ctctgtgagg gtcatccttt agcccagaaa gaggaattag tcatggagga tttagcggat
    11101 ttaccaacgg ttcgtttcac tcaagagaaa gacgagtacc tttattattc agagaacttt
    11161 gtcgatacca gcgctagctc acagatgttt aatgtgacag accgtgccac cttgaatggt
    11221 attttggagc ggacggacgc ctatgcgaca ggttctggat ttttagatag tgacagtgtt
    11281 aatggcatta cagttattcg tctcaaggat aacctagata accgcatggt ctatgttaaa
    11341 cgtgaagaag tggagcttag tcaagctggg actctcttcg tagaagtcat gcaagaatat
    11401 tttgatcaaa agaggaaatc atgaaaaaaa gagcaatagt ggcagtcatt gtactgcttt
    11461 taattgggct ggatcagttg gtcaaatctt atatcgtcca gcagattcca ctgggtgaag
    11521 tgcgctcctg gatccccaat ttcgttagct tgacctacct gcaaaatcga ggtgcagcct
    11581 tttctatctt acaagatcag cagttgttat tcgctgtcat tactctggtt gtcgtgatag
    11641 gtgccatttg gtatttacat aaacacatgg aggactcatt ctggatggtc ttgggtttga
    11701 ctctaataat cgcgggtggt cttggaaact ttattgacag ggtcagtcag ggctttgttg
    11761 tggatatgtt ccaccttgac tttatcaact ttgcaatttt caatgtggca gatagctatc
    11821 tgacggttgg agtgattatt ttattgattg caatgctaaa agaggaaata aatggaaatt
    11881 aaaattgaaa ctggtggtct gcgtttggat aaggctttgt cagatttgtc agaattatca
    11941 cgtagtctcg cgaatgaaca aattaaatca ggccaggtct tggtcaatgg tcaagtcaag
    12001 aaagctaaat acacagtcca agagggtgat gtcgtcactt accatgtgcc agaaccagag
    12061 gtattagagt atgtggctga ggatcttccg ctagaaatag tctaccaaga tgaggatgtg
    12121 gctgtcgtta acaaacctca gggaatggtt gtgcacccga gtgctggtca taccagtgga
    12181 accctagtaa atgccctcat gtatcatatt aaggacttgt cgggtatcaa tggggttctg
    12241 cgtccaggga ttgttcaccg tattgataag gatacgtcag gtcttctcat gattgctaaa
    12301 aacgatgatg cgcatctagt acttgcccaa gaactcaaag ataaaaagtc tctccgcaaa
    12361 tattgggcga ttgttcatgg aaatctgcct aatgatcgtg gtgtaattga agcgccgatt
    12421 ggccggagtg aaaaagaccg taagaaacag gctgtaactg ctaaagggaa gcctgcagtg
    12481 acgcgttttc acgtcttgga acgctttggc gattatagct tagtagagtt gcaactggag
    12541 acagggcgca ctcatcaaat ccgtgtccac atggcttata tcggccattc agtcgctggt
    12601 gatgaggtct atggtcctcg caagactttg aaaggacatg gacaatttct tcatgccaag
    12661 actttaggtt ttactcatcc gagaacaggt aagaccttgg aatttaaagc agatatccca
    12721 gagattttta aggaaacctt ggagagattg agaaagtaag aatgaaaaag aaattaacta
    12781 gtttagcact tgtaggcgct tttttaggtt tgtcatggta tgggaatgtt caggctcaag
    12841 aaagttcagg aaataaaatc cactttatca atgttcaaga aggtggcagt gatgcgatta
    12901 ttcttgaaag caatggacat tttgccatgg tggatacagg agaagattat gatttcccag
    12961 atggaagtga ttctcgctat ccatggagag aaggaattga aacgtcttat aagcatgttc
    13021 taacagaccg tgtctttcgt cgtttgaagg aattgggtgt ccaaaaactt gattttattt
    13081 tggtgaccca tacccacagt gatcatattg gaaatgttga tgaattactg tctacctatc
    13141 cagttgaccg agtctatctt aagaaatata gtgatagtcg tattactaat tctgaacgtc
    13201 tatgggataa tctgtatggc tatgataagg ttttacagac tgctgcagaa aaaggtgttt
    13261 cagttattca aaatatcaca caaggggatg ctcattttca gtttggggac atggatattc
    13321 agctctataa ttatgaaaat gaaactgatt catcgggtga attaaagaaa atttgggatg
    13381 acaattccaa ttccttgatt agcgtggtga aagtcaatgg caagaaaatt taccttgggg
    13441 gcgatttaga taatgttcat ggagcagaag acaagtatgg tcctctcatt ggaaaagttg
    13501 atttgatgaa gtttaatcat caccatgata ccaacaaatc aaataccaag gatttcatta
    13561 aaaatttgag tccgagtttg attgttcaaa cttcggatag tctaccttgg aaaaatggtg
    13621 ttgatagtga gtatgttaat tggctcaaag aacgaggaat tgagagaatc aatgcagcca
    13681 gcaaagacta tgatgcaaca gtttttgata ttcgacaaga cggtttagta aacatttcaa
    13741 cttcctacaa gccgattcca agttttcaag ctggttggca taagagttca tatggaaact
    13801 ggtggtatca agcgcctgat tctacaggag aatatgctgt cggttggaat gaaattaagg
    13861 gtgaatggta ttactttaac caaacgggta tcttattaca gaatcaatgg aaaaaatgga
    13921 acaatcgttg gttctatttg acagactctg gtgttgctgc taaaaattgg aagaaaatcg
    13981 ctggaatctg gtattatttt aacaaagaaa accagatgga aattggttgg attcaagata
    14041 aagagcagtg gtattatttg gatgttgatg gctctatgaa gacaggttgg cttcaatata
    14101 aggggcaatg gtattacttt gctccatcag gggaaatgaa aacgggctgg gtaaaagata
    14161 aagaagcctg gtactatatg gattctactg gtatcatgaa gacaggtgag atagaagttg
    14221 ctggacatca ttactatcta gaagaatcag gagctatgaa gcaaggctgg cttaaaaagg
    14281 caaatgattg gtatttctac aagacagatg gttcacgagc tataggttgg attaaagaca
    14341 aggataaatg gtacttcttg aaagaaaatg gtcaattact tgtgaatggt aagacaccag
    14401 aaggctatac tgtggattca agtggtgcct ggttagtgga tgttccgatc gagaaatctg
    14461 ctacaattaa aactacaagt cattcagaaa taaaagaatc caaagaagta gtgaaaaagg
    14521 atcttgaaaa taaagaaacg agtcaacatg aaagtgttac aaattcttca actagtcaag
    14581 atttgacatc ctcaacttca caaagctctg aaacgagtgt aaacaaatcg gaatcagaac
    14641 agtagtagaa aagaaggttt tagggccttc tttttcctat caactctttt ctatttcctg
    14701 ttattcatgt tataatggat aaatatgaat aatcggagtg agactatgaa atacaaacgg
    14761 attgtcttta aggtgggtac ttcttctctg acaaatgagg atggaagttt atcacgtagt
    14821 aaggtaaagg atattaccca gcagttggct atgctgcacg aggctggtca tgagttgatt
    14881 ttggtgtctt caggtgccat tgcggctggt tttggagcct taggatttaa aaagcgtccg
    14941 actaaaattg ctgataaaca ggcttcagca gcggtagggc agggactttt gttggaagaa
    15001 tatacgacca atcttctctt gcgtcaaatc gtttctgcac aaatcttgct gacccaagat
    15061 gactttgtgg ataagcgtcg ttataaaaat gcccatcagg ctttgtcggt tttgctcaac
    15121 cgtggggcaa ttcctatcat caatgagaat gatagtgtcg ttattgatga gctcaaggtt
    15181 ggggacaatg acactctaag tgctcaagta gcggcgatgg tccaagcaga ccttttagtt
    15241 ttcttgacag atgtggacgg tctctatact ggaaatccta attcagatcc aagagccaaa
    15301 cgcttggaga gaatcgagac catcaatcgt gagattattg atatggctgg tggagctggt
    15361 tcgtcaaacg gaactggggg tatgttaacc aaaatcaagg ctgcaactat cgcgacggaa
    15421 tcaggagttc ctgtttatat ctgctcatcc ttgaaatcag attccatgat tgaggcggca
    15481 gaggagaccg aggatggttc ttactttgtt gctcaagaga aggggcttcg tacccagaaa
    15541 caatggcttg ccttctatgc tcagagtcaa ggttctattt gggttgataa aggggctgcg
    15601 gaagctctct ctcaacatgg aaagagtctt ctcttatctg gtatcgttga agcagaagga
    15661 gtcttttctt acggtgatat cgtgacagta tttgataagg aaagtggaaa atcacttgga
    15721 aaaggacgcg tgcaatttgg agcatctgct ttggaggata tgttgcgttc tcaaaaagcc
    15781 aagggtgtct tgatttaccg tgacgactgg atttccatta ctcctgaaat ccaactactt
    15841 tttacagaat tttagaggta aactatggtg agtagacaag aacaatttga acaggtacag
    15901 gctgttaaaa aatcgattaa cacagctagt gaagaagtga aaaaccaagc cttgctagcc
    15961 atggctgatc acttagtggc tgctactgag gaaattttag cggctaatgc cctcgatatg
    16021 gcagcggcta aggggaaaat ctcagatgtg atgttggatc gtctttattt ggatgcagat
    16081 cgtatagaag cgatggcaag aggaattcgt gaagtggttg ccttaccaga tccaatcggt
    16141 gaagttttag aaacaagtca gcttgaaaat ggtttggtta tcacaaaaaa acgtgtagct
    16201 atgggtgtca tcggtattat ctatgaaagc cgtccaaatg tgacgtctga tgcggctgct
    16261 ttgactctta agagtggaaa tgcggttgtt cttcgtagtg gtaaggatgc ctatcaaaca
    16321 acccatgcca ttgtcacagc cttgaagaag ggcttggaga cgactactat tcatccaaat
    16381 gtgattcaac tggtggagga tactagccgt gaaagtagtt atgctatgat gaaggccaag
    16441 ggctatctag accttctcat tcctcgtgga ggagctggct tgatcaatgc agtggttgag
    16501 aatgcgattg tacctgttat cgagacaggg actgggattg tccatgtcta tgtggataag
    16561 gatgcagacg aagacaaggc gctgtctatc atcaacaatg ctaaaaccag tcgtccttct
    16621 gtttgtaatg ccatggaggt tctgctggtt catgaaaaca aggcagcaag catccttcct
    16681 cgcttggatc aaatgctggt tgcagatcga aaagaagctg ggttggaacc aattcaattc
    16741 cgcctagata gcaaagcaag ccagtttgtt tcaggtcaag ctgctcaagc acaagacttt
    16801 gataccgagt ttttagacta tattctagct gttaaggttg tgagcagttt agaagaagcg
    16861 gttgcgcata ttgaatccca cagtacccat cattcggatg ctattgtgac ggaaaatgct
    16921 gaagctgcag catactttac agatcaagtg gactctgcag cggtgtatgt taatgcctca
    16981 actcgtttca cagatggagg acaatttggt cttggttgtg aaatggggat ttctactcag
    17041 aaattgcaca cgcgtggtcc aatgggcttg aaagagttga ccagctacaa gtatgtggtt
    17101 gctggtgatg ggcagataag ggagtaagag atgaagattg gatttatcgg tttggggaat
    17161 atgggtgcta gcttggcaaa atctgtcttg cagactagga cgtcagatga gattctcctt
    17221 gccaatcgta gtcaagctaa ggtagatgct ttcattgcag actttggtgg tcaggcttcc
    17281 agcaatgaag aaatgtttgc agaagcagat gtgatttttc taggagttaa gcctgctcag
    17341 ttttctgaac tgctttctca atatcagacc atccttgaaa aaagagaaag tcttcttttg
    17401 atttcgatgg cagctggatt gaccttagaa aaactagcaa gtcttatccc aagccaacac
    17461 cgaattattc gtatgatgcc taatacccct gcttctatcg ggcaaggagt gattagttat
    17521 gccttgtctc ctaattgcag ggctgaggac agtgagatct tttgtcagct tttagccaag
    17581 gctggtctct tggttgaatt aggagaaagc ttaatcaatg cagcgacagg tcttgcaggt
    17641 tgtggaccag cctttgtcta tctctttatt gaggccttgg cagatgcagg tgttcagacg
    17701 ggattaccac gagaaacagc cttgaaaatg gcagcccaaa ctgtggtagg agctgggcaa
    17761 ttggtcctag aaagccagca acatcctgga gttttgaaag atcaagtttg tagtccaggc
    17821 ggttcgacta ttgctggcgt agcaagctta gaagcgcatg cttttcgagg catagtcatg
    17881 gaggcagttc atcaagccta taaacgaaca caagaactag gtaaataaga ggtagctttg
    17941 actgcctctt ttatggtggc tgaaatgaga agacacaaaa agattgtcac aaactcctat
    18001 ttttttgata gaatagaagt agtaaaaaag aaatgagtta gacatgtcaa aaggattttt
    18061 agtctctctt gagggaccag agggagcagg caagaccagt gttttagagg ctctgctacc
    18121 aattttagag gaaaaaggag tagaggtgct gacgacccgt gaacctggcg gagtcttgat
    18181 tggggagaag attcgggaag tgattttgga tccaagtcat actcagatgg atgctaaaac
    18241 agagctactt ctctatattg ccagtcgcag acagcatttg gtggaaaaag ttcttccagc
    18301 ccttgaagct ggcaagttgg tcatcatgga tcgttttatc gatagttctg ttgcctatca
    18361 gggatttggt cgtggcttag atattgaagc cattgactgg ctcaatcagt ttgcgacaga
    18421 tggcctcaaa cccgatttga cactctattt tgacatcgag gtggaagaag ggctggctcg
    18481 tattgctgct aatagtgacc gcgaggttaa tcgtttggat ttggaagggt tggacttgca
    18541 taaaaaagtt cgtcaaggct acctttctct tctggataaa gagggaaatc gcattgtcaa
    18601 gattgatgct agtctccctt tggagcaagt tgtggaaact accaatgctg tcttgtttga
    18661 cggaatgggc ttggccaaat gaaacaagat caactaaagg cttggcaacc agctcagttt
    18721 gaccgttttg tccgtatctt agaacaagac cagctcaatc acgcctatct cttttcaggt
    18781 ttctttggaa gcttggaaat ggcgcaattt ttagctaaga gccttttttg tacggataaa
    18841 gttggcgtct taccatgtga gaaatgccga agttgcaagc tgattgaaca ggaagagttt
    18901 ccagatgtca ccttgattaa gccagtcaat caggtcatca agacagaacg tattcgggaa
    18961 ttggtgggac agttttctca agcagggatt gaaagccagc aacaggtctt tatcatcgag
    19021 caagcggata aaatgcatcc caacgcagcc aattctctgc tcaaggtcat cgaagaaccc
    19081 cagagtgaag tttatatttt cttcttgact agcgatgagg aaaagatgtt accgacaatc
    19141 cgaagtcgga ctcagatctt ccactttaaa aagcaagaag aaaaacttat cttactctta
    19201 gaacaaatgg gacttgttaa gaaaaaagcg actcttttag ctaagtttag tcaatcgcga
    19261 gctgaagcag aaaagttggc acatcaggca agtttttgga ccttggtcga tgaaagtgaa
    19321 cgcctgctga cttggttagt agctaagaaa aaagaaagtt atctacaggt tgccaaatta
    19381 gccaacttgg cagatgataa ggaaaaacag gatcaggttt tacggattct tgaagttctc
    19441 tgtgggcagg acctcttgca ggtaagagta agagtgattc tacaagattt actagaagct
    19501 agaaaaatgt ggcaagctaa tgtcagcttt caaaatgcca tggaatatct ggtcttgaaa
    19561 gaaatataaa ctcaaaaatg aatgataaag aaaggaaagg gctgttttat ggacaaaaaa
    19621 gaattatttg acgcgctgga tgatttttcc caacagttat tggtaacctt ggccgatgtg
    19681 gaagccatca agaaaaatct caagagcctg gtagaggaaa atacagctct tcgtttggaa
    19741 aattctaagt tgcgagaacg cttgggtgag gtggaagcag atgctcctgt caaggccaag
    19801 catgttcgtg aaagtgtccg tcgcatttac cgtgatggat ttcacgtatg taatgatttt
    19861 tatggacaac gtcgagagca ggacgaggaa tgtatgtttt gtgacgagtt gctatacagg
    19921 gagtaggcat gcagattcaa aaaagtttta aggggcagtc tccctatggc aagctgtatc
    19981 tagtggcaac gccgattggc aatctagatg atatgacctt tcgagctatc cagaccttga
    20041 aagaagtaga ttggattgct gctgaggata cgcgcaatac aggtcttttg ctcaagcatt
    20101 ttgacatttc caccaagcag atcagttttc atgagcacaa tgccaaggaa aaaattcctg
    20161 atttgattgg tttcttgaaa gcagggcaaa gtattgctca ggtctctgat gccggtttgc
    20221 ctagcatttc agaccctggt catgatttag ttaaggcagc tattgaggaa gaaattgcag
    20281 ttgtgacagt tccaggtgcc tctgcaggaa tttctgcctt gattgccagt ggtttagcgc
    20341 cacagccaca tatcttttac ggttttttac cgagaaaatc aggtcagcag aagcaatttt
    20401 ttggcttgaa aaaagattat cctgaaacac agatttttta tgaatcacct catcgtgtag
    20461 cagacacgtt ggaaaatatg ttagaagtct acggtgaccg ctccgttgtc ttggtcaggg
    20521 aattgaccaa aatctatgaa gaataccaac gaggtactat ctctgagtta ttagaaagca
    20581 ttgctgaaac gccactcaag ggcgaatgtc ttctcattgt tgagggtgcc agtcagggtg
    20641 tggaggaaaa ggacgaggaa gacttgttcg tagaaattca aacccgcatc cagcaaggta
    20701 tgaagaaaaa tcaagctatt aaggaagtag ctaagattta ccagtggaat aagagtcaac
    20761 tctacgctgc ctaccacgac tgggaagaaa aacaataaag ggagatagga tgtaataatt
    20821 ctgtctgttt ctgtttaact taattagtga tgataatata aagatgtatc acttggtata
    20881 gaagctttgg tattaagttt tttattaagc ccatacggaa taccgatggt tggagcagca
    20941 gttatagcgt tcttagaagg tataaataga aaaataaggt cattttaaat caaaggattg
    21001 ataaatcaga aagaaggtga ttttttgcga acatacgaaa ataaagaaga actaaaagct
    21061 gagatagaga aaacatttga gaaatatatt ttagaatttg ataatattcc agaaaattta
    21121 aaagataaga gagctgatga agttgacaga actccagcag aaaaccttgc ttatcaggtt
    21181 ggttggacca acttggttct taaatgggaa gaagatgaaa gaaaggggct tcaagtaaaa
    21241 acaccatcgg ataaatttaa atggaatcaa cttggtgaat tatatcagtg gttcacagat
    21301 acctacgctc atttatctct gcaagagttg aaagcaaaat taaatgaaaa tattaattct
    21361 atctctgcaa tgattgattc gttgagtgag gaagaattat ttgaaccgca tatgagaaag
    21421 tgggctgatg aagcgactaa aacagcgact tgggaagtgt ataagtttat tcatgtaaat
    21481 acggttgcac cttttggaac tttcagaact aaaatcagaa aatggaagaa gatagtatta
    21541 taaattatat ttttaacttt aaaaaatttc ataaaaatgg ttaccaaagg cgatagaaga
    21601 aaaactatcg tctttttctt tgcaaatttt taagaaggga ggtgatcttg catggacttt
    21661 gaatattttt ataacagaga agcggaaaga tttaacttct taaaagtacc ggagatatta
    21721 gttgatagag aagaatttcg gggcttatca gcagaagcaa ttatccttta ttccatactt
    21781 cttaaacgga caggaatgtc atttaagaat aactggatag acaaggaagg cagagtattt
    21841 atctatttta ctgtcgaaga aattatgaaa agaagaaata tctcaaagcc aactgccata
    21901 aaaacattag atgagcttga tgtaaaaaaa aggaatagga ctgatcgaaa gagtaaggct
    21961 tggacttggt aagccgaaca tcatttatgt taaagacttt atgagtatat ttcaggtaaa
    22021 agaaaatgac ttacaaaagt caaaaaactt aacttcagaa gtaaaagatt ttaacctcag
    22081 aagtaaagaa aatgaacttc aagaggttaa gaaccttgac tctaactata tagagaataa
    22141 taagagtaag tatagtaaga gagaatatag ttttggtgaa aacggacttg gaacatttca
    22201 aaatgtgttt ttagctgttg aagatatatc ggatttacaa atcataatga actcacagct
    22261 tgagaattac attagacttc ctgcaaaact agaatcctag ttcatgattg ataataccag
    22321 caatcaaatt cattcgtaat ccgaagcgtt tacgatgatt tcgataggtt gttgaaaaca
    22381 ttttaaacgt ttttactttg gcaaagatgt tctcaacctt gcttctttcc ttagatagcg
    22441 catggttata ggctttatct tcagctatta gcgacttgag tttgctggat ttacgtggag
    22501 tttgtacttg aggatatatc ttcatgagcc cttgataacc actgtcagcc aagattttac
    22561 cagcttgtcc gatatttctg caactcattt tgaacaactt catatcacga caatagttca
    22621 cagtgatatc caaagaaaca attctccctt gacttgtgac aatcgcttga gccttcatag
    22681 cgtggcattt ctttttacca gaatcattcg ctaattcttt ttttagggcg attgatttgt
    22741 acttccgtcg catcaatcat taccgtgtcc tcagagctga gaggagttct tgaaaccgta
    22801 acaccacttt gaacaagagt tacttcaacc cattggctcc gacggataaa gttgctttcg
    22861 tgaataccaa aatcagccgc aatttgttca taagttcgat attctcgcac tattgaagag
    22921 tggccataag aaggtcttct aggcttaatt taggttttcg tccacctttt gcgtgtttaa
    22981 gttgataagc tgtttttaat acagctaata tctcttcaaa agtcgtgcgc tgaacaccaa
    23041 caagacgctt aaatcgtgca tcagttagtt gtttacttgc ttcatcattc atagaactac
    23101 tataccatat tttgtttcgc aggaagtcta ttggaaagta agaaatattg aagctgaggc
    23161 tattagaaga aattgtgagc gtggtgctat tttttcaggt aaaataaaat atcacgaaga
    23221 ttcacagttt aaaggagatc actatgttga atgttatgct gttttagata atacggttat
    23281 agcaagagat agaataacag tccctatcga tccgttatgt ggaaaagatt ttatagagta
    23341 gcatataatt gattcttaac tggaatactc tttatctctt tacatcaaga aaatgactaa
    23401 acagggaagt ttgccttctt cccttttttt gttatactag tagaagaaaa aaatagaaag
    23461 atttgtggga gtgaaaaagt cctgtggact ttttcagcct gagccaagaa actcgaaagc
    23521 tcgtaagtct gattggcttt ttcaatgtga atcttaactt catactccca aagaggtatt
    23581 agtgtcgtgt ctcaatctta tatcaatgtt atcggtgctg gtttggcagg ttctgaagca
    23641 gcctaccaaa tcgcagagcg tggtattcca gttaaacttt atgaaatgcg tggtgtcaag
    23701 tcaacacctc agcacaaaac agacaatttt gctgagttgg tttgttccaa ttccttgcgt
    23761 ggagatgctt tgacaaatgc tgttggcctc cttaaggaag aaatgcgtcg cttgggttct
    23821 gtgattttgg aatctgctga ggctacacgt gttcctgcag gtggtgccct tgcagtggac
    23881 cgtgatggtt tctctcaaat ggtgaccgaa aaagttgcca accacccctt gattgaagtg
    23941 gttcgtgatg aaattacaga attgccgaca gatgttatta cggttatcgc tactggtcct
    24001 ttgacaagtg atgccttggc tgaaaagatt catgccctta atgacggtga tggtttttat
    24061 ttctacgatg cggcagcgcc tattatcgat gtcaacacta tcgatatgag caaggtctac
    24121 ctcaaatcac gttatgataa gggagaagcg gcctacctca atgcccctat gaccaagcaa
    24181 gaatttatgg atttccatga agctttggtc aatgcagaag aagcaccgct taattctttt
    24241 gaaaaagaaa agtactttga aggatgtatg cctatcgaag tcatggccaa acgtggcatt
    24301 aaaaccatgc tttatggtcc tatgaaacca gttggtcttg agtatccgga cgactacaca
    24361 ggacctcgtg atggagaatt taaaacacct tatgcggttg tccagctccg tcaggataat
    24421 gcagctggta gcctatacaa tattgttggt ttccagaccc acctcaaatg gggagaacaa
    24481 aagcgtgtct tccaaatgat tccgggtctt gaaaatgcgg agtttgtccg ttatggtgtc
    24541 atgcatcgca attcttacat ggattcacca aatcttcttg agcagactta ccgttccaag
    24601 aaacaaccaa atctcttctt tgctggtcag atgacggggg tggaaggcta tgttgagtcg
    24661 gcggcttcgg gcttagttgc gggaattaac gcagctcgtc tcttcaagga agaaagcgag
    24721 gttattttcc ccgagacgac agcgattgga agcttagctc attacattac ccatgccgac
    24781 agcaaacatt tccaaccaat gaatgtcaat tttgggatca tcaaggagtt ggaaggcgag
    24841 cgtatccgtg ataagaaggc tcgttatgaa aaaattgcag agcgtgccct tgccgactta
    24901 gaggaatttt tgactgtcta atttttttga aagaattgct catgatacta taaaaatctt
    24961 agaaattgtg ataaaatagg taggatgaaa gaaggagagt gaaaatggcg aatcccaagt
    25021 ataaacgtat tttaatcaag ttatcaggtg aagcccttgc cggtgaacgt ggcgtaggga
    25081 ttgatatcca aacagttcaa acaatcgcaa aagagattca agaagttcat agcttaggta
    25141 tcgaaattgc ccttgttatt ggtggaggaa atctttggcg tggagaacct gcagcagaag
    25201 caggtatgga ccgtgttcag gcagattaca ctggaatgct tgggactgtt atgaatgctc
    25261 ttgtgatggc agattcattg caacaagttg gggttgatac gcgtgtacaa acagctattg
    25321 ctatgcaaca agtggcagag ccttatgtcc gtggacgtgc ccttcgtcac cttgaaaaag
    25381 gccgtatcgt tatctttggt gctggaattg gttcaccata cttctcgaca gatacaacag
    25441 cggcccttcg tgcagctgaa atcgaagcag atgccatcct catggctaaa aatggcgtcg
    25501 atggtgtgta caatgccgat cctaagaagg acaagacagc cgttaagttt gaagaattga
    25561 cccaccgtga tgttatcaac aaaggtcttc gtatcatgga ctcaacagcc tcaaccctct
    25621 caatggacaa cgacattgac ttggttgtct tcaacatgaa ccaatcaggc aacatcaaac
    25681 gtgtcgtatt tggtgaaaat atcggaacaa cagtttcaaa taatatcgaa gaaaaggaat
    25741 aagaaagaat atggctaacg taattattga aaaagctaaa gagagaatga cccaatctca
    25801 ccaatcactt gctcgtgaat ttggtggtat ccgtgctggt cgtgccaatg caagcttgct
    25861 tgaccgtgta catgtagaat actatggagt cgaaactcct cttaaccaaa tcgcttcaat
    25921 tacgattcca gaagcgcgtg ttttgttggt aacaccattt gacaagtctt cattgaaaga
    25981 catcgaacgt gccttgaacg cttctgatct tggtatcaca ccggctaatg acggttctgt
    26041 gattcgcttg gttatcccag ctcttacaga agaaactcgt cgtgaccttg ctaaagaagt
    26101 gaagaaggtc ggcgaaaatg ctaaagtggc tgtccgcaat atccgtcgcg atgctatgga
    26161 cgaagctaag aaacaagaaa aagcaaaaga aatcactgaa gacgaattga agactcttga
    26221 aaaagatatt caaaaagtaa cagacgatgc tgttaaacac atcgacgaca tgactgctaa
    26281 caaagagaaa gaacttttgg aagtctaaaa ataaacagaa aaactcagtt ggcattgctg
    26341 gctgagtttt attcgaaaga aggaaatatg aatacaaatc ttgcaagttt tatcgttgga
    26401 ctgatcatcg atgaaaatga ccgtttttac tttgtgcaaa aggatggtca aacctatgct
    26461 cttgctaagg aagaaggtca acatacagta ggggatacgg tcaaaggttt tgcatacacg
    26521 gatatgaagc aaaaactccg cctgacaacc ttagaagtga ctgccactca ggaccaattt
    26581 ggttggggac gtgtcacaga ggttcgtaag gatttgggtg tctttgtgga tacaggcctt
    26641 cctgacaagg aaatcgttgt gtcactcgat attctccctg agctcaagga actctggcct
    26701 aagaagggcg accaactcta catccgtctt gaagtggata agaaagaccg tatctggggc
    26761 ctcttggctt atcaagaaga cttccaacgt cttgctcgtc ctgcctacaa caacatgcag
    26821 aaccaaaact ggccagccat tgtttaccgt ctcaagctgt caggaacttt tgtttaccta
    26881 ccagaaaata atatgcttgg ttttattcat cctagcgagc gttacgcaga gccacgtttg
    26941 gggcaagtat tagatgcgcg cgttattggt ttccgtgaag tggaccgcac tctgaacctc
    27001 tccctcaaac cacgctcctt tgaaatgttg gaaaacgatg ctcagatgat tttgacttat
    27061 ttggaaagta atggcggttt catgacctta aatgataagt catctccaga cgacatcaag
    27121 gcaacctttg gcatttctaa aggtcagttc aagaaagctt taggtggtct tatgaaggct
    27181 ggtaaaatca agcaggacca gtttgggaca gagttgattt agggaggctt atgagaaaat
    27241 cattttacac ttggctcatg accgagcgca atcctaaaag taacagtccc aaagcaattt
    27301 tggcagacct cgcttttgaa gaggcagctt ttccaaaaca tacagatgat tttgatgagg
    27361 tcagtcgctt tttggaggag catgccagtt tctcttttaa cctaggagat tttgacagca
    27421 tttggcagga atatctagaa cactagcatt tattcattgg gtttgggcta gtaatttctc
    27481 catccctctg ctataataaa aagaaataaa aggattagag aggttcttta tttgaaggaa
    27541 cattcaatag acattcaact gagtcatcca gatgacctgt ttcatctttt tggttccaat
    27601 gaacgccatc ttcgtttgat ggaagaagag cttgatgttg tgattcatgc tcgtacggag
    27661 attgtccagg ttttgggaga agagtctgcc tgtgaggaag cccgtcaagt tattcaggct
    27721 ttgatggtct tggtaaatcg tgggatgacc gttggtacgc cagatgtagt cactgcgatt
    27781 agcatggtca aaaatgatga aattgacaag tttgtcgccc tttacgaaga agaaattatc
    27841 aaagataata ctgggaaacc tatccgtgtc aaaaccctag ggcaaaagct ttatgtggac
    27901 agtgtcaaac agcatgatgt gacctttgga attgggccag caggtacagg gaagaccttc
    27961 cttgcagtga ccttggcagt gactgccctt aaacgtgggc aagtcaagcg aattatccta
    28021 actcgtccag cggtggaagc gggagagagt cttggatttc ttccgggtga tcttaaggag
    28081 aaggtggatc cttaccttcg tcctgtttac gatgccttgt atcagattct ggggaaagac
    28141 caaacaactc gactcatgga gcgtgaaatt atcgagattg cgccccttgc ctatatgcgt
    28201 ggacggacct tggatgatgc ctttgtcatt ctcgatgagg cgcaaaatac gaccatcatg
    28261 cagatgaaga tgttcttgac tcgtttaggt tttcattcta agatgattgt caatggagat
    28321 attagtcaga ttgacctgcc acgtaatgtc aagtccggtt tgattgatgc tcaagagaaa
    28381 ctcaagaaca tccatcagat tgactttgtt catttttcag ccaaggatgt ggttcgccat
    28441 ccagttgtcg ctcagattat ccgagcctat gaatattcta ctgaagttgc acacgactga
    28501 ttttgaggaa gtttgcctgc aaaagaatat acttttgaga gaggaaaatc cagttgtata
    28561 ggctaaaggt tttatccaaa ggtttgagac aacgattagg cacgatggaa agaactttta
    28621 tgtggctgat gacgatcagt gcatcttcct gtgtcataat cacagggcac aagaaagtag
    28681 gaatttgaaa agatgattga ccaactatct aagtattaca gttgtaggat actaactgaa
    28741 aaggatattc caagtatttt atctttatat gaaagtaatc ctctgtattt tcagcattgt
    28801 ccaccagagc caaattttgc aactgtaaaa gaggacatgc tttgtctacc tgaaggtaaa
    28861 gctaaggctg ataagttttt tgttggattt tggaatggat ctgaccttgt ggctgttata
    28921 gattttgtct atgcacatcc tgatgaggag actgttttta ttggtttgtt tatggttgat
    28981 caagcctatc agaggaaagg gattggtagt catattgtga cagaagcact agcttatttt
    29041 gctaagaact ttcgaaaggc acgtttggct tatgttaagg gaaatccgca atctcagcat
    29101 ttttgggaaa agcagggctt taaatcaatt ggatgcgagg ttaagcaaga actctatacg
    29161 gttgttatcg ctgaacagag cctagaagat tagaaatggc atcaagtaag aactatttgg
    29221 aatttgtttt ggaacaatta tcaggattag atgatgtgac ttaccgttcc atgatggggg
    29281 agtatattct ttacttccgc ggcaagatta ttggcggcat ttatgacgat cgctttttag
    29341 ttaaacccgt gcaagcagtc ttagataaga ttgaccaatc ttcttttgag tttccataca
    29401 aaggtgccaa agaaatgatt tgagtggaag aacttgataa taagatgttt ctataagacc
    29461 tgattttagc tatgtataac caactgccaa cgcccaaacc taaaaagaaa aagcaagggt
    29521 gaacgaagta aaaaagaagt ctgctaaggc cctgtctttg cacgggtaaa attttatata
    29581 taaaaagaag ctgggactaa agagctcagc ttcctttggt ttatataatt gtcattacaa
    29641 gacgaagtgg ttgggcgaaa ctctgttgac tttattcaat ttagagtttc ttatgcacaa
    29701 ttgagtctgg aacgaaagtc tccagttgca aagtatacag tacaataaac caacgatgta
    29761 atagctgatg acacaaagca cagtgggtag gacttgcgaa gtcacccttt tcttttcaaa
    29821 atttatacta aatcattgat atcagtgtag tcacgattaa gtccttgagc aactggtagg
    29881 ctagtcaagt aaccttgata agtggtcaca ccttgacgca agccttcatc ttcagagatt
    29941 gcttgtgcga atcctttgcc agccaaagct tcgatataag gaagagtgac attggttagg
    30001 gcgatggttg aagtgcgggc aaccgcacca gggatattgg caacggcata gtggagaaca
    30061 ccgtgttttt catagacggg ttcatcgtgc gttgtcacac ggtcagctgt ttcgataacg
    30121 ccaccttggt caacagcaac gtcaacgata cagagcctgg acgcatttgt ttgaccatct
    30181 catctgtcac caattccggt gcttttgcac cagggatgag aatggctcca atcaccacat
    30241 cagcatctct catacttgct tcaatgttga atgaattaga tataagagtt tgaatttgac
    30301 ttccaaagac ttcttctaga actgagagac gcttggcact aatatctaaa atagtcactt
    30361 gagcaccaag accaagggcg atgcgggcag catgtgtacc gacgacacca tcaccgatga
    30421 tagttacttt tccttttgga acacctggta caccaccagg tagaacacca gagccaccag
    30481 cttgcttagt aaggaagtga gctccgattt aaacagccat acgacctgca acctcactca
    30541 taggaacgag gagcggtagt tgtccttgat tgtcacgaac agtttcatag gcaattcctg
    30601 ttgtttttgc tgctaacata gcatctgcta attctggagc agcggccatg tgcaagtagg
    30661 tgaagagaag aagatcgtcg cgcaagtaac cgtattcaga acttaaaggt tcttttactt
    30721 tcacaaccaa ctctgctgcc caagcttcac cagcagtagc gacaatctca gctccttgct
    30781 tttgatagtc agcatcagta aagccagaac cgagaccagc atttgtttcg ataaggacac
    30841 gatgaccacg actaactaag ctatgaacac ctgcaggtgt gagggcgaca cggttttcgt
    30901 tatttttaat ttcttttggg attccgatta acattgagat aacctacctt tcaattgacg
    30961 gtcttgtttt ggttgtcaca ttccagttca taaatcaaaa atgtgacggt ttcattgtat
    31021 atgaaaccgc ttcaaaaatc aagaaaaact tgtcatccaa atttttttat gctagactag
    31081 tgaaaatcaa gctctaatgg agggaaaagt atggaatcaa tatttgtgaa atttgcccag
    31141 tatccgtcta tagaaacgga gcgtttattg cttagacctg taactttgga tgatgcggaa
    31201 gcaatgtttg actatgcctc ggacaagggt aatacacgtt acacttttcc aaccaatcaa
    31261 agcttggaag aaaccaagaa taacattgct cagttctact tggctaatcc cttgggacgt
    31321 tgggggattg aattaaaaga taacggcaag tttatcggaa ctattgactt acacaagatt
    31381 gatcctgttc ttaagaaggc agctattggc tacattatca ataaaaagta ttggaatcaa
    31441 ggattaacgc cagaaaccaa tcgtgctgtg attgagctag cttttgagaa gataggaatg
    31501 aataagttag ttgctttata cgataaggac aattctgcgt caggaaaggt catggagaaa
    31561 tcaggcatgc gtttttccca tgcagaacca tatgcttgta tggaccagca tgaaaaaggc
    31621 cgaatcgtga caagagttca ttatgtcttg accaaggaag actattttgc aaataaataa
    31681 gcagttgaaa agaaattttt cgactgtttt ttcttcctct tacgaataat ctaagagagg
    31741 agaaaatatg gaagcaatta tcgagaaaat caaagagtat aaaatcatcg tcatctgtac
    31801 tggtctgggc ttgcttgtag gcggattttt cctgctaaag ccagctccac aaacacctgt
    31861 aaaggaaacg aatttgcagg ctgaagttgc agctgtttcc aaggatttgg tatccgaaaa
    31921 ggaagtgaac aaggaagaga aggaagaacc ccttgaacaa gatctaatca cagtagatgt
    31981 caaaggtgct gtcaaatcgc cagggattta tgacttgcct gtaggtagtc gagtcaatga
    32041 tgctgttcag aaggctggtg gcttgacaga gcaagcagac agcaagtcgc tcaatctagc
    32101 tcagaaagtt agtgatgagg ctctggttta cgttcctact aagggagaag aagcagttag
    32161 tcaacagact ggttcgggga cagcttcttc aataagcaag gaaaagaagg tcaatctcaa
    32221 caaggccagt ctggaagaac tcaagcaggt caagggactg ggaggaaaac gagctcagga
    32281 cattatcgac catcgtgagg caaatggcaa gttcaagtca gtagacgagc tcaagaaggt
    32341 ctctggcatt ggtggcaaaa caatagaaaa gcttaaagac tatgttacag tggattaaga
    32401 atttctctat tcccctaatt tacctgagtt ttctattact ttggctttat tacgctattt
    32461 tctcagcatc ttatcttgct ttgttgggct ttgtttttct gctagtctgt ctctttatcc
    32521 aatttccgtg gaaatctgct ggtaaagttc taataatttg cggaatcttt ggattttggt
    32581 ttgtttttca aaattggcaa cagagtcaag cgagtcaaaa tctggcggat tctgttgaaa
    32641 gggtacggat tttgcctgat actattaagg ttaatggtga tagtctatcc tttcgtggca
    32701 agtctaacgg tcgtgctttc caagtctatt ataaactcca gtccgaggag gagaaagaag
    32761 cctttcaagc tttaaccgac ctgcatgaga taggactaga agggaagctt tcggagccag
    32821 aagggcagag aaattttggt ggctttaatt accaagccta tctgaagact cagggaattt
    32881 accagactct caatatcaaa acaatccagt cacttcaaaa gattggcagt tgggatatag
    32941 gagaaaactt gtccagttta cgtcgaaagg ctgtggtttg gattaagacg cactttccag
    33001 accctatgcg caattacatg acaggactct tgctgggaca tctggacacc gactttgagg
    33061 agatgaatga gctttattcc agtctaggaa ttatccacct ctttgcccta tctggtatgc
    33121 aggtaggttt tttcatgaat ggatttaaga aacttctctt gcgattgggc ttgacccaag
    33181 aaaagttgaa atggctgact tatccctttt cccttatcta tgcgggacta actggatttt
    33241 cagcatcggt tattcgcagt ctcttgcaaa agctactggc tcaacatggg gttaagggct
    33301 tggataattt tgccttgacg gtgcttgtcc tctttattgt catgccaaac tttttcttga
    33361 cagcaggagg agtcttgtcc tgcgcttatg cttttatcct gaccatgacc agcaaagaag
    33421 gggaggggct caaggctgtt actagtgaaa gtctagtcat ctccttgggc atattgccca
    33481 ttctatcctt ctattttgcg gaatttcaac ctttgtctat ccttttgacc tttgtctttt
    33541 cctttctatt tgacttgacc ttcttaccgc tcttgtctat tttatttgtc ctttcctttc
    33601 tctatccagt cattcagctg aactttatct ttgaatggtt ggagggcatt attcgcttgg
    33661 tgtcacaggt gacaagtaga cctctggtct ttggacaacc caatgcatgg tttttaatcc
    33721 tattgttaat ttccttggct ttggtctatg atttgagaaa aaacattaaa aagctaacgg
    33781 tattgtgctt attgattaca gggctctttc tcctgaccaa gcatccactg gaaaatgaaa
    33841 tcaccatgct ggatgtgggg caaggagaaa gtattttcct acgggatgta actgggaaaa
    33901 ccattctcat agatgtaggt ggtaaggcag aatcttataa gaaaatcgaa aaatggcaag
    33961 aaaaaatgac gaccagcaat gcccagcgaa ccttgattcc ctatctcaaa agtcgaggag
    34021 tagctaagat tgaccagcta attttgacta acacggacaa ggagcatgtt ggagatttgt
    34081 cagaggtgac caaggctttc catgtagggg agattctagt atcaaaagac agtctgaaac
    34141 agaaggaatt tgtggcagaa ctacaggcga ctcaaacaaa ggtgcgtagt atgacagtag
    34201 gggagaactt gcccattttt ggaagtcagt tagaagttct atctccaagg aaaatgggag
    34261 atggaggaca cgatgatacc ctagttctgt atgggaaatt cttggataag caatttctct
    34321 tcacgggaaa tttggaggag aaaggagaga aggacttgct gaagcactat ccagacttga
    34381 aagtaaatgt tttgaaagct agccaacatg gcaataaaaa atcatcaagt ccagcctttc
    34441 tagaaaaact caaaccagag cttactctta tctcagttgg aaagagcaat cgaatgaaac
    34501 tcccccatca ggaaacattg acacgactgg aaggtatcaa tagcaaagtt tatcgaactg
    34561 accagcaagg agctatacgt tttaaggggt tggatagttg gaaaatcgaa agtgttcgat
    34621 aggaaggata aatgttgtag attagtgaaa taaactaaaa atttgttgca taataatgat
    34681 aaaaatggta taatgaaaac gtattcaata ttgaggatat aaaatcatta aaaattagca
    34741 aaaatcgttt aattagttag tttatgatta ttggtctttt tcagtccagt atatctgctg
    34801 tgacagtcac taaaagttac aagtatgatt ggaatacggt ttgggaatat agtaccaact
    34861 atcacgacca tcagtatgct tggattccgt catggtctcg ttatgacagc tattctgagt
    34921 atccagttgg ttctggctgg aactacggtc gttatgagat cataaactat tacagcggag
    34981 gctattaatt cttaaagagt gagaaaaagg agggctagat atgttgcagc ttactcatgt
    35041 gaccttaaaa acgcgacaag tcatcttgca agatgtggat ttcaccttta aaaagggtag
    35101 ggtttatggt cttcttgcta tcaatggctc tggaaagacg accctgttcc gtgccattag
    35161 caatttaatt cccataagta gtggaaatat cgcagcccct ccttctttat tttattatga
    35221 gagtattgaa tggctggatg gaaacttaag tgggatggac taccttcgtc ttatcaaaaa
    35281 catctggaag tcaggtctga acttgaggga tgaaatcgcc tattgggaaa tgtctgacta
    35341 tatcagtctt cccattcgca agtattcctt aggcatgaag caacgcttgg tgattgccat
    35401 gtatttcctc agtcaggcca aatgctggct catggatgag attacaaatg gcttagatga
    35461 gtattatcga cagaagtttt ttgataggct agcacaaatc gatagacaag aacagctggt
    35521 tcttttaagt tcccactata aggaagagtt ggttgatgtc tgcgatagag tagtaaccat
    35581 tcatcagggg cagatagaag aggtttagtt tatgaaagat gttagtctat ttttattgaa
    35641 aaaagttttc aaaagccgct taaactggat tgtcttagct ttatttgtat ctgtactcgg
    35701 tgttaccttt tatttaaata gtcagactgc aaactcacac agcttggaga gcaggttgga
    35761 aagtcgcatt gcagccaacg agagggctat caatgaaaat gaagagaaac tctcccaaat
    35821 gtctgatacc agctcggagg aataccagtt tgctaaaaat aatttagacg tgcaaaaaaa
    35881 tcttttgacg cgaaagacag aaattctaac tttactaaaa gaagggcgct ggaaagaagc
    35941 ctactatttg cagtggcaag atgaagagaa gaattatgaa tttgtatcaa atgacccgac
    36001 tgctagctct ggcttaaaaa tgggggttga ccgcgaacgg aagatttacc aagccctgta
    36061 tcccttgaac ataaaagcac atactttaga gtttccgacc cacgggattg atcagattgt
    36121 ctggatttta gaggttatca tcccaagctt gtttgtggtt gcgattattt ttatgctaac
    36181 acaactattt gcagaaagat atcaaaatca tctggacaca gctcacttat atcctgtttc
    36241 aaaagtgaca tttgcaatat cctctcttgg agttggagtg ggatatgtaa ctgtgctgtt
    36301 tatcggaatc tgtggctttt cttttctagt gggaagtctg ataagtggtt ttggacagtt
    36361 agattatccc tacccgattt atagcttagt gaatcaagag gtaactattg gaaagatgca
    36421 ggatgtatta tttcctggct tgctcttagc tttcttagcc tttatcgtca ttgtggaagt
    36481 tgtgtatttg attgcttact ttttcaagca aaaaatgcct gtcctctttc tttcactcat
    36541 tgggattgtt ggcttattgt ttggcatcca aaccattcag cctcttcaaa agattgcaca
    36601 tctgattccc tttacttact tgcgttcagt ggagatttta tctggaagat tacctaagca
    36661 gattgataat gtcgatctaa attggagcat ggggatggtc ttacttcctt gcctgattat
    36721 ccttttgtta gtggggattc tatttatcga aagatgggga agttcacgta aaaaggaagt
    36781 ttttaaagtt tagttttcct atagggaagc taaagaaaaa ctaacatagg gagagaatca
    36841 acttggttct ctctttttga ttcgaaaacc aaaccaaaat acaaacacaa acttttcaaa
    36901 aaataacttt ttatcttgac aagagctaga aaacttggta tcatataaaa gttgagaaaa
    36961 gcagaagtga gagcttctcg ccttgtgaca ttaagttgcc tggccctacg gatgaaaagt
    37021 ttcgaagaaa cgctatcata acgtgcgggc ttgtatattt acgagtccgc tattgttttt
    37081 ctctaataaa acaaaagagg tgaaaaccat agcaaagcaa gacttattca tcaatgatga
    37141 gattcgtgta cgtgaagttc gcttgattgg tcttgaggga gaacagctag gcatcaagcc
    37201 actcagtgaa gcgcaagctt tggctgataa cgctaatgtt gacctagtat tgattcaacc
    37261 ccaagccaaa ccgcctgttg caaaaattat ggactacggt aagttcaaat ttgagtacca
    37321 gaagaagcaa aaagaacaac gtaaaaaaca aagcgttgtt actgtgaaag aagttcgtct
    37381 aagtccaaca attgacaagg gtgactttga tacaaaactt cgtaatgcac gtaagttcct
    37441 tgaaaaagga aataaagtta aggtatctat tcgctttaag ggtcgtatga ttacccataa
    37501 agagattggt gcaaaagttt tagccgagtt tgctgaagca actcaagata ttgccatcat
    37561 cgaacaacgt gctaaaatgg atggacgtca aatgttcatg caattggcgc cagcgactga
    37621 caaaaaataa ttgtcagaaa gttaaataaa ggagaaaaaa tcatgccaaa acaaaaaaca
    37681 caccgcgcat cagctaaacg tttcaaacgt acaggttctg gtggacttaa acgtttccgt
    37741 gcttacactt ctcaccgttt ccacggaaaa actaagaaac aacgtcgtca tcttcgtaaa
    37801 gcatctatgg tgcattcagg agattacaaa cgtatcaaag caatgcttac tcgcttgaaa
    37861 taatagcttg actgtaagta aacaattcta gaaaatattt ggaggaaata aaacatggca
    37921 cgtgttaaag gtggcgttgt atcacgcaaa cgtcgtaaac gtattcttaa attagcaaaa
    37981 ggttactatg gagctaaaca catcttgttc cgtactgcaa aagaacaagt aatgaactct
    38041 tactactatg cataccgtga ccgtcgtcag aaaaaacgtg acttccgcaa attgtggatt
    38101 actcgtatca atgcggcggc tcgtatgaac ggactttcat actcacaatt gatgcatggt
    38161 ttgaaattgg ctgagatcga agttaaccgt aaaatgcttg ctgacttggc tgttaacgat
    38221 gcagtagctt tcacagctct tgcagatgca gctaaagcaa aacttggtaa ataacaactg
    38281 atgagactgg aacaggattg tccagtcttt ttaaaaataa aggagaaaga tatggcttca
    38341 aaaatgctac acacttgctt acgagtagaa aatcttgaaa aatcaatcgc attttatcaa
    38401 gatgcttttg gttttaaaga attgcgtcgc agagattttc cagaccatgc cttcacgatt
    38461 gtctatctag gtcttgaggg tgatgattat gagttggagt tgacttataa ctacgatcac
    38521 ggtccgtatg tggttggtga tgggtttgcc catatcgccc tcagtacacc tgatcttgag
    38581 gcacttcatc aagaacacag tgcaaaaggc tatgaagtga ctgagccaaa tggtctacca
    38641 ggaactacac caaactatta ctttgttaaa gaccctgatg gatataaggt cgaagtcatt
    38701 cgtgaaaaat aatttcgtgc aagttaagta gaatattcgt tttctacttg acttttttta
    38761 gctgaaagag tatactaata aaaattcaac ctttaagggg agtccagaga gactcacaag
    38821 gtgtcagata aaagaatagt gcaattttct agaggagacc ttttgagtgt gctctcttgt
    38881 gttgtacgat tttaactgag gccttgcact agcaaggtct tttctttatc tggtcccctt
    38941 aaaatttaag gaggaaaagt tatgaatctc acatgtaaga agcgtttggg tgtcattcgg
    39001 ttggaaacca tgaaggtggt tgcacaagag gaaatcgcgc cagcaatctt tgaattagtc
    39061 ctagaaggag aaatggttga agccatgcga gcaggccaat ttcttcatct gcgtgtacca
    39121 gacgatgccc atctcttacg tcgtcctatt tcaatttcgt ctattgacaa ggcaaacaag
    39181 cagtgtcacc tcatttatcg gattgaggga gctgggactg caattttttc aaccttaagt
    39241 cagggagaca ctcttgatgt gatggggcct cagggaaatg gttttgactt gtctgacctt
    39301 gatgagcaga atcaggttct ccttgttggt ggtgggattg gtgttccacc cttgcttgag
    39361 gtggccaagg aattgcatga acgtggagtg aaagtagtga cagtcctcgg ttttgctaat
    39421 aaggatgctg ttattttgaa aacggaattg gctcagtatg gtcaggtctt tgtaacgaca
    39481 gatgatggtt cttatggcat caagggaaat gtttccgttg ttatcaatga tttagacagt
    39541 cagtttgatg ctgtttactc gtgtggggct ccaggaatga tgaagtatat caatcaaacc
    39601 tttgatgatc acccaagagc ctatttatct ctggaatctc gtatggcttg tgggatggga
    39661 gcttgctatg cctgtgttct aaaagtacca gaaagcgaga cggtcagcca acgcgtctgt
    39721 gaagatggtc ctgttttccg cacaggaaca gttgtattat aaggagaaaa ttatgactac
    39781 aaatcgatta caagtttctc tacctggttt ggatttgaaa aatccgatta ttccagcatc
    39841 aggctgtttt ggctttggac aagagtatgc caagtactat gatttagacc ttttaggttc
    39901 tattatgatc aaggcgacaa cccttgaacc acgttttgga aatccaactc caagagtggc
    39961 agagacgcct gctggtatgc tcaatgcaat tggcttgcaa aatcctggtt tagaggttgt
    40021 tttggctgaa aagctacctt ggctggaaag agaatatcca aatcttccta ttattgccaa
    40081 tgtagctggt ttttcaaaac aagagtatgc agctgtttct catgggattt ccaaggtaac
    40141 taatgtaaaa gctatcgagc tcaatatttc ttgtcccaat gttgaccact gtaatcatgg
    40201 acttttgatt ggtcaagatc cagatttggc ttatgatgtg gtgaaagcag ctgtggaagc
    40261 ctcagaagtg ccagtttatg tcaaattaac cccgagtgtg accgatatcg ttactgtcgc
    40321 aaaagctgca gaagatgcgg gagcaagtgg cttgaccatg atcaatactc tggttggaat
    40381 gcgctttgac ctcaaaacca gaaaaccaat cttggccaat ggaacaggtg gaatgtcagg
    40441 tccagcagtc tttccagtag ccctcaaact catccgccaa gtagcccaaa caacagacct
    40501 gcctatcatt ggaatggggg gagtggattc ggctgaagct gccctagaaa tgtatctggc
    40561 tggggcatct gctatcggag ttggaacagc taactttacc aatccttatg cctgccctga
    40621 catcatcgaa aatttaccaa aagtcatgga taaatacggt attagcagtc tggaagaact
    40681 ccgtcaggaa gtaaaagagt ctctgaggta aactgcaatc aatctgttct tgatttttta
    40741 ttagtttgta atatgaattt aggagaattt tggtacaata aaataaataa gaacagagga
    40801 agaaggttaa tgaagaaagt aagatttatt tttttagctc tgctattttt cttagctagt
    40861 ccagagggtg caatggctag tgatggtact tggcaaggaa aacagtatct gaaagaagat
    40921 ggcagtcaag cagcgaatga gtgggttttt gatactcatt atcaatcttg gttctatata
    40981 aaagcagatg ctaactatgc tgaaaatgaa tggctaaagc aaggtgacga ctatttttac
    41041 ctcaaatctg gtggctatat ggccaaatca gaatgggtag aagacaaggg agccttttat
    41101 tatcttgacc aagatggaaa gatgaaaaga aatgcttggg taggaacttc ctatgttggt
    41161 gcaacaggtg ccaaagtaat agaagactgg gtctatgatt ctcaatacga tgcttggttt
    41221 tatatcaaag cagatggaca gcacgcagag aaagaatggc tccaaattaa agggaaggac
    41281 tattatttca aatccggtgg ttatctactg acaagtcagt ggattaatca agcttatgtg
    41341 aatgctagtg gtgccaaagt acagcaaggt tggctttttg acaaacaata ccaatcttgg
    41401 ttttacatca aagaaaatgg aaactatgct gataaagaat ggattttcga gaatggtcac
    41461 tattattatc taaaatccgg tggctacatg gcagccaatg aatggatttg ggataaggaa
    41521 tcttggtttt acctcaagtt tgatgggaaa atagctgaaa aagaatgggt ctacgattct
    41581 catagtcaag cttggtacta cttcaaatcc ggtgg
//
LOCUS       DAVLBE010000013        40273 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.013, whole genome shotgun sequence.
ACCESSION   DAVLBE010000013 DAVLBE010000000
VERSION     DAVLBE010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 40273)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40273)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40273
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.013"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            5..75
                     /locus_tag="VXB91_000729"
     tRNA            5..75
                     /locus_tag="VXB91_000729"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:37..39,aa:Gly,seq:tcc)
     gene            110..183
                     /locus_tag="VXB91_000730"
     tRNA            110..183
                     /locus_tag="VXB91_000730"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:144..146,aa:Ile,seq:gat)
     gene            266..355
                     /locus_tag="VXB91_000731"
     tRNA            266..355
                     /locus_tag="VXB91_000731"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:302..304,aa:Ser,seq:tga)
     gene            366..439
                     /locus_tag="VXB91_000732"
     tRNA            366..439
                     /locus_tag="VXB91_000732"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:400..402,aa:Met,seq:cat)
     gene            443..515
                     /locus_tag="VXB91_000733"
     tRNA            443..515
                     /locus_tag="VXB91_000733"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:476..478,aa:Phe,seq:gaa)
     gene            528..608
                     /locus_tag="VXB91_000734"
     tRNA            528..608
                     /locus_tag="VXB91_000734"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:562..564,aa:Tyr,seq:gta)
     gene            613..683
                     /locus_tag="VXB91_000735"
     tRNA            613..683
                     /locus_tag="VXB91_000735"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:645..647,aa:Trp,seq:cca)
     gene            698..770
                     /locus_tag="VXB91_000736"
     tRNA            698..770
                     /locus_tag="VXB91_000736"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:731..733,aa:His,seq:gtg)
     gene            784..855
                     /locus_tag="VXB91_000737"
     tRNA            784..855
                     /locus_tag="VXB91_000737"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:816..818,aa:Gln,seq:ttg)
     gene            865..948
                     /locus_tag="VXB91_000738"
     tRNA            865..948
                     /locus_tag="VXB91_000738"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:899..901,aa:Leu,seq:caa)
     gene            1055..2332
                     /locus_tag="VXB91_000739"
     CDS             1055..2332
                     /locus_tag="VXB91_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HEV0470221.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     MKDLFHYLVSTLDLTVAKVDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATSEIQAFALNGDEVIIYPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKSLRRQFSKKNLTDEEETTIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            2408..3892
                     /locus_tag="VXB91_000740"
     CDS             2408..3892
                     /locus_tag="VXB91_000740"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HEV0470222.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPDTYPKVDLNF
                     DKLKDASYQEVAKLVLSAFLDDFTVEELDYCINNAYDSKFDTPAIAPLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFANVPGT
                     EIIVFYPKDGVSKIQELQMTTQTGDNTHVIAIDGNFDDAQTNVKHMFNDVALREKLTT
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIVAGEKVNFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNNAEKTTELMNALNTQGQYKLTDFDAEILDLFAAEYATEEETAAEIKRVCELDS
                     YIEDPHTAVASAVYKKYQSATGDVTKTVIASTASPYKFPVVAVEAVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLEIAPIRHKTTVAAADMQAAVEAYLGL"
     gene            3953..5233
                     /locus_tag="VXB91_000741"
     CDS             3953..5233
                     /locus_tag="VXB91_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEV0470223.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTIVSRLVGLVILWSQLKLPYGKPTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVATA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMSLKG"
     gene            5237..5857
                     /locus_tag="VXB91_000742"
     CDS             5237..5857
                     /locus_tag="VXB91_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV0470224.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQDLLVRVAEDRNLDVEVLNQVRAQSLAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNAFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLNSDNTY
                     YIGDRTLDVEFAQNSGIQSINFLESTYEGNHRIQALADISRIFETK"
     gene            6023..7135
                     /locus_tag="VXB91_000743"
     CDS             6023..7135
                     /locus_tag="VXB91_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEV0470225.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVLWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEVTKTVIASEEVAPST
                     GTSVPEEQTTETTRPVEEATPQETTPAEKQETQASPQAASAVEVTTTSSEAKEVASSN
                     GATAAVSTYQPEETKIISTTYEAPAAPDYAGLAVAKSENAGLQPQTAAFKEEIANLFG
                     ITSFSGYRPGDSGDHGKGLAIDFMVPERSELGDKIAEYAIQNMASRGISYIIWKQRFY
                     APFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG"
     gene            7458..7883
                     /locus_tag="VXB91_000744"
     CDS             7458..7883
                     /locus_tag="VXB91_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HEV0470226.1"
                     /translation="MLEIQDLLYQLRLSEQASTQLFEKRLGISLTRYQILLFLLEHSP
                     CNQMAVQERLKIDQAALTRHFKILETEGLVERHRNPENQREVLVEAAKYAKEQLVVNP
                     PLQHIRVKEEIESILTEFERTELSRLLNKLVLGIENIEI"
     gene            7894..8253
                     /locus_tag="VXB91_000745"
     CDS             7894..8253
                     /locus_tag="VXB91_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HEV0470227.1"
                     /translation="MSIILTTIVALEHFYIFYLESIATQSDATSRVFNMEKEELAHPS
                     VSSLFKNQGIYKALLGVFLLYVIYFSQNLEIVTIFVLFVIGAATYGSLTADKKIILKQ
                     GGSAILALISILLFKYT"
     gene            8360..9004
                     /gene="pcp"
                     /locus_tag="VXB91_000746"
     CDS             8360..9004
                     /gene="pcp"
                     /locus_tag="VXB91_000746"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEV0470228.1"
                     /translation="MKVLVTGFEPFGGEKGNPALEAIKGLPAEIHGAEVRWLEVPTVF
                     HKSAQVLEEEMNRYQPDFVLCIGQAGGRTSLTPERVTINQDDACISDNEDNQPIDRPI
                     RPDGASAYFSSLPIKAMVQAIKKEGLPASVSNTAGTFVCSHLMYQALYLVEKKSPYVK
                     AGFMHIPYMMEQVVNRPTTPAMSLVDIRRGIEAAIGAIIEHGDQELKLVGGETH"
     gene            complement(9032..9889)
                     /locus_tag="VXB91_000747"
     CDS             complement(9032..9889)
                     /locus_tag="VXB91_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HEV0470229.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSGFLNP
                     LSRIHGTVLEQPFFSILGQILQTYLFPLLVSFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQHFVLDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            10019..11161
                     /gene="tgt"
                     /locus_tag="VXB91_000748"
     CDS             10019..11161
                     /gene="tgt"
                     /locus_tag="VXB91_000748"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HEV0470230.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREYFVEKYGYNKSGRNF"
     gene            11259..13076
                     /locus_tag="VXB91_000749"
     CDS             11259..13076
                     /locus_tag="VXB91_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEV0470231.1"
                     /translation="MRIKWFSLIRIIGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNNEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     AGVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGMVFLLSAAAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQEPKIISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPILQTLRPLPYIHAILVAGTGILTIIVCTVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTA
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHHMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPIKSK"
     gene            13229..14380
                     /gene="nagA"
                     /locus_tag="VXB91_000750"
     CDS             13229..14380
                     /gene="nagA"
                     /locus_tag="VXB91_000750"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HEV0470232.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            14543..15601
                     /locus_tag="VXB91_000751"
     CDS             14543..15601
                     /locus_tag="VXB91_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HEV0470233.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVN
                     SSDPEKAIKEIYDLTDGRGVDVAIEAVGIPATFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            15752..16117
                     /locus_tag="VXB91_000752"
     CDS             15752..16117
                     /locus_tag="VXB91_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HEV0470234.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            16193..17134
                     /locus_tag="VXB91_000753"
     CDS             16193..17134
                     /locus_tag="VXB91_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HEV0470235.1"
                     /translation="MVQEIAQEIIRSARKKGTQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDQKMASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAS
                     RDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            17082..18098
                     /locus_tag="VXB91_000754"
     CDS             17082..18098
                     /locus_tag="VXB91_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HEV0470236.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSALLDKQCVIQMRAGLSQGKSFSEMMESLGCSSTIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
                     LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEIGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
     gene            18100..18426
                     /locus_tag="VXB91_000755"
     CDS             18100..18426
                     /locus_tag="VXB91_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HEV0470237.1"
                     /translation="MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKE
                     AVNDKGKAAVVKVVESQAELYSLDKNEDATLSKLQGDGRITEEQVKAYNEYYTKNGGA
                     NRKVND"
     gene            18419..18823
                     /locus_tag="VXB91_000756"
     CDS             18419..18823
                     /locus_tag="VXB91_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HEV0470238.1"
                     /translation="MIKAFTMLESLLVLGLVSILALGLSSSVQSTFAAVEEQIFFMEF
                     EELYRETQKRSVASQQKTSLNLDGQTLSNGSQKLTVPKGIQAPSGQSITFDRAGGNSS
                     LAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            18828..19088
                     /locus_tag="VXB91_000757"
     CDS             18828..19088
                     /locus_tag="VXB91_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0470239.1"
                     /translation="MILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVA
                     KMALQTGQNQVSINGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            19051..19512
                     /locus_tag="VXB91_000758"
     CDS             19051..19512
                     /locus_tag="VXB91_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEV0470240.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQTMSQLLI
                     SEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGNRLYMKQDGKDIAIGKSKSDDFR
                     KTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES"
     gene            19490..19936
                     /locus_tag="VXB91_000759"
     CDS             19490..19936
                     /locus_tag="VXB91_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001851880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEV0470241.1"
                     /translation="MWKKKKVKAGVLLYAVTIAAIFSLLLQFYLNRQIAHYQDYALNK
                     EKLVAFAMAKRTKDKAEQESGEQVFNLGQVSYQNKKTSLVTTVRTSKSQYEFLFPSVK
                     IKEEKRDKKEEVATDSSEKAEKKNQKRSLKRKRIPSQFNYNALNPE"
     gene            20039..20626
                     /locus_tag="VXB91_000760"
     CDS             20039..20626
                     /locus_tag="VXB91_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV0470242.1"
                     /translation="MKHDFNHKAETFDSPKNIFLANLVCQAVEKQIDILSDKVILDFG
                     GGTGLLALPLAKQAKSVTLVDISEKMLEQARLKVEQQAIKNIQFLEQDLPKNPLEKEF
                     DCLAVSRVLHHMPDLDAAFSLFHQHLKEDGKLIIADFTKTEANHHGFDLAELENKLIE
                     HGFSSVHSQILYSAEDLFQGNHSEFFLIVAQKSLA"
     gene            20687..21640
                     /locus_tag="VXB91_000761"
     CDS             20687..21640
                     /locus_tag="VXB91_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV0470243.1"
                     /translation="MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFKEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEMDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGL
                     KYLKSDGYAIFLAPSNLLTSPQSDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKNEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            21691..22881
                     /locus_tag="VXB91_000762"
     CDS             21691..22881
                     /locus_tag="VXB91_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEV0470244.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHTQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYFAVLNGADAIVFTAGVGE
                     NAENFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            23030..23401
                     /gene="rnpA"
                     /locus_tag="VXB91_000763"
     CDS             23030..23401
                     /gene="rnpA"
                     /locus_tag="VXB91_000763"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HEV0470245.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYREGNGSEKETKVD"
     gene            23376..24200
                     /locus_tag="VXB91_000764"
     CDS             23376..24200
                     /locus_tag="VXB91_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEV0470246.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYF
                     FAKIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            24219..25205
                     /locus_tag="VXB91_000765"
     CDS             24219..25205
                     /locus_tag="VXB91_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HEV0470247.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVDAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QTENQDLKEMGLKVEQSYDIAQVATDVTAYVQAIVDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNRYSKTFYVTINVNDYVEHRAEVLQTYAQKL
                     AIRVLEEGRSHQTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            25256..25879
                     /locus_tag="VXB91_000766"
     CDS             25256..25879
                     /locus_tag="VXB91_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P"
                     /protein_id="HEV0470248.1"
                     /translation="MLNKIRDYLDFAGLQYRNPDKAGAEREKMLAFRHKGQEARKAFT
                     ELAKAFQASHPEWQLQQTSQWMNQAQRLRPHFWVYLQRDGQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLGKQAKVLDIPTVKGIYYLTYSNGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            26010..27467
                     /locus_tag="VXB91_000767"
     CDS             26010..27467
                     /locus_tag="VXB91_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEV0470249.1"
                     /translation="MEVVSSVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKATVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIAAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSLMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFTFGLIGQLITIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLASYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFLLVIPQLQFAKAKDKEKYYNGEVQEEA"
     gene            27490..27771
                     /locus_tag="VXB91_000768"
     CDS             27490..27771
                     /locus_tag="VXB91_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0470250.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            27848..28333
                     /locus_tag="VXB91_000769"
     CDS             27848..28333
                     /locus_tag="VXB91_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0470251.1"
                     /translation="MNLKQALIDNDSIRLGLEANNWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELEDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            28350..29015
                     /locus_tag="VXB91_000770"
     CDS             28350..29015
                     /locus_tag="VXB91_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HEV0470252.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAADPAGAARAFKDEIKR
                     IWG"
     gene            29019..29882
                     /locus_tag="VXB91_000771"
     CDS             29019..29882
                     /locus_tag="VXB91_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HEV0470253.1"
                     /translation="MVRPIGIYEKATPTHFTWLERLNFAKELGFDFVEMSIDERDERL
                     ARLDWSKEERLEVVKAIYETGVRIPSICFSGHRRYPLGSKDPVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKACDWAEEAQVVLAIEIMDDPFIN
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTES
                     SKGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAIQEAQAF
                     LYPLIKKAGLM"
     gene            29884..30588
                     /locus_tag="VXB91_000772"
     CDS             29884..30588
                     /locus_tag="VXB91_000772"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HEV0470254.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYKAWSEIGSVVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVAYEKDTGLVIVEEFEHRGL
                     NPVEVPGIVVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVGPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            30767..32440
                     /locus_tag="VXB91_000773"
     CDS             30767..32440
                     /locus_tag="VXB91_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEV0470255.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALVDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVILQVSKSQGYHLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEITFMLQVLPYLLLSCHNVEQYQERHQDIEKEFSLIRKRIEYQVSKKLGERLF
                     QKFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQIRMEIE
                     NKDDLLRNLMIHCKALLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILEGAWFI
                     RLTDDDIAYLTIHIGGFLKYTPSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYFPNEQI
                     DTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYLKHNIF
                     RNKSKSFSENLSSLISSYIVDSKLASKFQEEVQTLINKEIVVQAFLEDI"
     gene            32552..33643
                     /gene="ulaG"
                     /locus_tag="VXB91_000774"
     CDS             32552..33643
                     /gene="ulaG"
                     /locus_tag="VXB91_000774"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HEV0470256.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            33757..35733
                     /gene="tkt"
                     /locus_tag="VXB91_000775"
     CDS             33757..35733
                     /gene="tkt"
                     /locus_tag="VXB91_000775"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEV0470257.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVADYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDTNRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVSAAKEL
                     ASQGEKIRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAV
                     LGIDTFGASAPAPKVLAEYGFTVENLVKIVRNLK"
     gene            35850..36149
                     /gene="yajC"
                     /locus_tag="VXB91_000776"
     CDS             35850..36149
                     /gene="yajC"
                     /locus_tag="VXB91_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEV0470258.1"
                     /translation="MNPNITFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVDGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            36196..36624
                     /locus_tag="VXB91_000777"
     CDS             36196..36624
                     /locus_tag="VXB91_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HEV0470259.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQEYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNISDLCQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            36626..37036
                     /locus_tag="VXB91_000778"
     CDS             36626..37036
                     /locus_tag="VXB91_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0470260.1"
                     /translation="MENLTNFYEKYRVYLTRPRLELLAVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            37336..39987
                     /gene="adhE"
                     /locus_tag="VXB91_000779"
                     /gene_synonym="adhC"
     CDS             37336..39987
                     /gene="adhE"
                     /locus_tag="VXB91_000779"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HEV0470261.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSAHA
                     ARIVRDAAIAAGAPENCVQWITQPSMEATSALMNHEGVATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFKPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTIHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
BASE COUNT        12222 a         7216 c         9064 g        11771 t
ORIGIN      
        1 tttagcgggt gtagtttagt ggtaaaacta cagccttcca agctgttgtc gcgagttcga
       61 ttctcgtcac ccgctttgaa ctttgttctt tgtaccaagt ttttaacttg ggcgcgtagc
      121 tcaggtggtt agagcgcacg cctgataagc gtgaggtcgg tggttcgagt ccactcgtgc
      181 ccatagtgtt tagtccatta ctaggggatt ggaatattat ctgttcacta agaggacacg
      241 ggcttgttcc cgtataaact attttggagg attacccaag tccggctgaa gggaacggtc
      301 ttgaaaaccg tcaggcgtgt aaaagcgtgc gtgggttcga atcccacatc ctccttttat
      361 attaacgcgg gatggagcag ctcggtagct cgtcgggctc ataacccgaa ggtcgtaggt
      421 tcaaatcctg ctcccgcaat aaggctcggt agctcagttg gtagagcaat ggattgaagc
      481 tccatgtgtc ggcggttcga ttccgtctcg cgccatttat atattttgga agggtagcga
      541 agaggctaaa cgcggcggac tgtaaatccg ctccttcggg ttcgggggtt cgaatccctc
      601 cccttccatt ttacgggcat agtttaaagg tagaactaag gtctccaaaa ccttcagtgt
      661 gggttcaatt cctactgccc gtgttaatag aattatggcg ggtgtggtga agtggttaac
      721 acaccagatt gtggctctgg catgcgtggg ttcgatcccc atcactcgcc tattttatat
      781 tattggggta tagccaagcg gtaaggcaag ggactttgac tccctcatgc gttggttcga
      841 atccagctac cccagttact atttgccggc gtggcggaat tggcagacgc gctggactca
      901 aaatccagtg tccgcaagga cgtgccggtt cgaccccggc cgccggtata gtatagtgtt
      961 aggaacgttg ttattcttcg ttcctttttt atattatttt tggtataatt atagttattc
     1021 aaattttatt tagattaaga aagtgtaggg gagtatgtct tgttctatcg atttattaaa
     1081 acatcggtat ttgaaaaata ttaaagaaaa tcctgaattg tttgtcggaa ttgagttgga
     1141 gtatcctgtt gcaagtttag aaggggatgc tacagatgtt gaagttatga aggatctatt
     1201 tcattattta gtttctactt tggatctcac cgtagcaaag gtagatgatt ttggcaatct
     1261 gatccagtta gtagatccga taagtcagga tgctatttta tttgaagttt cctatacaac
     1321 gattgagttt gcatttggta aggctgaaac gattcaagag gtcgaaaatc gtttcaataa
     1381 ttatatgaat gtaattcaga gaaagttagc tgaatcaaat catgctattg ttggctgtgg
     1441 tatccatccc aactgggata aaaatgagaa ttgtccagtg gcttatccac gctatcagat
     1501 gttgatggat tatttgaatt tgagtagaaa tattattaaa tcagatttac atcatttccc
     1561 tgaatatggt acttttatct gtgggagcca ggttcagctg gatatttcaa aaaccaacta
     1621 cttacgggtg attaatgctt ttactcaaat tgaagcggct aaggcttatt tatttgcaaa
     1681 ctctgaattt tcgggtgcgg attgggatac gaaaatttca agggatattt tctgggaaga
     1741 atctatgcat ggtatctatc cagagaatgt tggggtcaat gctagactcc ttaatgatga
     1801 agctgatttt tttgactatc taaatcattc tgcgattttt actgcggaac gtgatgggca
     1861 gacctattat ttttatccta ttcaggctgg ggactatttg gctacgtccg aaatccaagc
     1921 atttgctctg aatggggatg aggttattat ttacccccaa gagaaggatt ttgaaactca
     1981 tcgtagttac cagtaccaag atttaacgac tcgaggaaca gttgagtttc gtagtgtgtg
     2041 tacacagcca cttgatagga cttttgcttc tgcagctttt cacttgggat tattggttaa
     2101 tttagacaag ttagaagctt acttagaaac agcacctttc tttaaagtat ttggttatga
     2161 ttacaagtct ttaaggagac aattttctaa gaaaaatctt acagatgagg aagaaactac
     2221 gattattgaa ttttccaaag acttactcct actagctgag gagggactag tggtgagaaa
     2281 taaggaagaa atgacctatt tacagccttt gagagaagaa ttgagcctat aatttctctt
     2341 ataaagggag aattttctga aaaatcatga tataatggac gagactatag ataaaggata
     2401 gagagtaatg acattagttt atcaatcaac gcgtgatgcc aacaatacag taactgccag
     2461 ccaagcaatt ttgcaaggtt tggcgacgga cggcggtttg tttacaccgg atacttatcc
     2521 aaaggtagat ttgaactttg acaaattgaa agatgcttct taccaggaag ttgctaagct
     2581 agttttgtca gcatttttag atgactttac agttgaggag ttggactact gtatcaacaa
     2641 tgcctacgat agcaaatttg atactccagc tattgcacca ttagtgaaat tagatgggca
     2701 atacaatttg gaacttttcc atggttcaac gattgccttt aaggatatgg ccttgtctat
     2761 tttgccatac tttatgacga ctgctgctaa gaaacatggt ttggagaaca agattgttat
     2821 cttgacagcg acatctggtg acacggggaa agctgctatg gcggggtttg cgaatgtgcc
     2881 tggtactgag attatcgtct tttatccaaa ggatggtgtc agcaagattc aagagttaca
     2941 aatgaccact cagactggcg acaatactca tgttattgct attgatggta actttgacga
     3001 tgcgcaaaca aatgtgaagc acatgtttaa cgacgtggct cttcgtgaaa aattgactac
     3061 caacaagttg caattttcat cagctaactc tatgaacatt ggtcgtctgg tgccacaaat
     3121 tgtttattat gtttatgctt acgctcaatt ggttaagact ggtgaaattg tagctggtga
     3181 aaaggttaac ttcacagtac caacaggaaa ctttggaaat atcttggctg ccttttatgc
     3241 caaacaaatt ggtttgccag ttggtaaatt aatctgtgct tcaaatgaca acaatgtttt
     3301 gacagacttc tttaaaacac gtgtctatga caaaaaacgt gagtttaagg taacaaccag
     3361 cccatctatg gatatcttgg tatcttcaaa cttggagcgc ttgattttcc atcttttggg
     3421 aaataatgct gaaaagacaa ctgaacttat gaatgccttg aacacgcaag gacaatataa
     3481 gttgacagac tttgatgcag agattttgga cctctttgca gctgaatatg cgactgagga
     3541 agaaacggca gcagagatca agcgtgtttg tgagttagat tcttatatcg aggaccctca
     3601 tacagctgtt gcttcagcag tttataaaaa ataccaatcg gccactggag atgtaactaa
     3661 gacagtgatt gcttcaacag ctagtccata caagttccca gtagttgcag tagaagctgt
     3721 aactggaaaa gcaggtttaa cagactttga agccttggct caattacatg aaatctcagg
     3781 cgttgcagtg ccaccagcag ttgatgggct tgaaatagct ccaattcgtc acaagacaac
     3841 agtggcagct gctgacatgc aagcagcggt tgaggcttat ttaggacttt aagacagagg
     3901 gagcaaactc ggttgggaaa ccaactgagt ttcttttcat caggaggaga gattgtttaa
     3961 gaaaaataaa gacattctta atattgcatt gccagctatg ggtgaaaact ttttgcagat
     4021 gctaatggga atggtggaca gttatttggt tgctcattta ggattgatag ctatttcagg
     4081 ggtttcagta gctggtaata ttatcaccat ttatcaggcg attttcatcg ctctgggagc
     4141 tgctatttcc agtgttattt caaaaagcat agggcagaaa gaccagtcga agttggccta
     4201 tcatgtgact gaggcgttga agattacctt actattaagt ttccttttag gatttttgtc
     4261 catcttcgct gggaaagaga tgataggact tttggggacg gagagggatg tagctgagag
     4321 tggtggactg tatctatctt tggtaggcgg atcgattgtt ctcttaggtt taatgactag
     4381 tctaggagcc ttgattcgtg caacgcataa tccacgtctg cctctctatg ttagtttttt
     4441 atccaatgcc ttgaatattc ttttttcaag tctagctatt tttgttctgg atatggggat
     4501 agctggtgtt gcttggggga caattgtgtc tcgtttggtt ggtcttgtga ttttgtggtc
     4561 acaattaaaa ctgccttatg ggaagccaac ttttggttta gataaggaac tgttgacctt
     4621 ggctttacca gcagctggag agcgacttat gatgagggct ggagatgtag tgatcattgc
     4681 cttggtcgtt tcttttggga cggaggcagt tgctgggaat gcaatcggag aagtcttgac
     4741 ccagtttaac tatatgcctg cctttggcgt cgctacggca acggtcatgc tgttggcccg
     4801 agcagttgga gaggatgatt ggaaaagagt tgctagtttg agtaaacaaa ccttttggct
     4861 ttctctgttc ctcatgttgc ccctgtcctt tagtatatat gtcttgggtg taccattaac
     4921 tcatctctat acgactgatt ctctagcggt ggaggctagt gttctagtga cactgttttc
     4981 actacttggg acccctatga cgacaggaac agtcatctat acggcagtct ggcagggatt
     5041 aggaaatgca cgcctccctt tttatgcgac aagtatagga atgtggtgta tccgcattgg
     5101 gacaggatat ctgatgggga ttgtgcttgg ttggggcttg cctggtattt gggcagggtc
     5161 tctcttggat aatggttttc gctggttatt tctacgctat cgttaccagc gctatatgag
     5221 cttgaaagga taggaaatgc aaaaaacagc ttttatttgg gatttagacg ggactttatt
     5281 ggactcttac gaagcgattt tatcagggat tgaggagact tttgctcagt tttctattcc
     5341 ttatgataag gagaaggtga gagagtttat cttcaagtat tcggtgcaag atttgcttgt
     5401 gcgggtggca gaagatagaa atctggatgt tgaggtgcta aatcaggtgc gtgcccagag
     5461 tctggctgag aagaatgctc aggtagtttt gatgccaggt gcgcgtgagg tgctagcttg
     5521 ggcagacgaa tcaggaattc agcagtttat atatactcat aaggggaaca acgcttttac
     5581 cattctcaag gacttggggg tggaatccta ttttacagag attttaacca gtcagagtgg
     5641 ctttgtgcgg aagccaagtc cagaagcggc tacctatctg ctagataagt atcagttgaa
     5701 ttctgataat acttattata taggggatcg gactctggat gtggaatttg cccagaatag
     5761 tgggattcaa agcatcaact ttttagagtc tacttatgaa gggaatcaca ggattcaagc
     5821 gttagcagat atttcccgta tttttgagac taagtgataa aaagattgtg tcagttttgt
     5881 gacagagacc taacaaacta tttcaagtaa cctagtttgt tacaaggaat agacagttct
     5941 gttaaatagg cccgagaggg ctttttttct acattttttg tgttatgata gacaggtact
     6001 catttgaaag gaatttgaaa gaatgaagaa aagaatgtta ttagcgtcaa cagtagcctt
     6061 gtcatttgcc ccagtattgg caactcaagc agaagaagtt ctttggactg cacgtagtgt
     6121 tgagcaaatc caaaacgatt tgactaaaac ggacaacaaa acaagttata ccgtacagta
     6181 tggtgatact ttgagcacca ttgcagaagc cttgggtgta gatgtaacag tgcttgcgaa
     6241 tctgaacaaa atcactaata tggacttgat tttcccagaa actgttttga caacgactgt
     6301 caatgaagca gaagaagtaa cagaagttga aatccaaaca cctcaagcag actctagtga
     6361 agaagtgaca actgcgacag cagatttgac cactaatcaa gtgaccgttg atgatcaaac
     6421 tgttcaggtt gcagaccttt ctcaaccaat tgcagaagtt acaaagacag tgattgcttc
     6481 tgaagaagtg gcaccatcta cgggcacttc tgtcccagag gagcaaacga ccgaaacaac
     6541 tcgcccagtt gaagaagcaa ctcctcagga aacgactcca gctgagaagc aggaaacaca
     6601 agcaagccct caagctgcat cagcagtgga agtaactaca acaagttcag aagcaaaaga
     6661 agtagcatca tcaaatggag ctacagcagc agtttctact tatcaaccag aagagacgaa
     6721 aataatttca acaacttacg aggctccagc tgcgcccgat tatgctggac ttgcagtagc
     6781 aaaatctgaa aatgcaggtc ttcaaccaca aacagctgcc tttaaagaag aaattgctaa
     6841 cttgtttggc attacatcct ttagtggtta tcgtccagga gacagtggag atcacggaaa
     6901 aggtttggct atcgacttta tggtaccaga acgttcagaa ttaggggata agattgcgga
     6961 atatgctatt caaaatatgg ccagccgtgg cattagttac atcatctgga aacaacgttt
     7021 ctatgctcca ttcgatagca aatatgggcc agctaacact tggaacccaa tgccagaccg
     7081 tggtagtgtg acagaaaatc actatgatca cgttcacgtt tcaatgaatg gataaacccg
     7141 acttgataac atcattttga cgaatgagat ctagctttcg tgatggaaag cgattctcgt
     7201 tcgttttttc tttgtcatac tcttcgaaaa tctcttcaaa ccacgtcagt tttatctgaa
     7261 acttcaaagc tgtgctttga gcaacctgcg actagcttcc tagtttgctt tttgattttc
     7321 attgagtatc aatttgaatg gaaaatggaa agttatcatc ttgtaatgag ttaagcaaca
     7381 ttcttgcaat ctattttact ttatatcaca attaattagt caaatattga taaatcaata
     7441 aaaagagagg ggaagaaatg ctagagattc aagatttact gtatcaactc cgcttgtctg
     7501 agcaagcgag tacgcaattg tttgaaaaaa ggcttgggat tagtttgaca cggtatcaga
     7561 ttttactgtt tttgctggag cattctcctt gtaaccaaat ggcggttcag gagcgtttga
     7621 aaattgatca ggctgctttg acacggcatt tcaaaatttt ggaaacggaa ggtttggtgg
     7681 agcgtcatcg taatcctgaa aatcagcggg aagtgttggt agaggctgcg aagtatgcca
     7741 aggagcagtt agtggtgaat ccccctctgc aacatatcag ggttaaggaa gagatagaaa
     7801 gtatcttaac agagtttgag agaacagaac tcagccgttt attaaataaa ttggttttgg
     7861 gtattgaaaa tatagaaatt taaggagaaa tagatgtcaa ttattttaac aacgatcgtt
     7921 gctttggagc atttttacat tttttatttg gaaagtattg ccacgcaatc agatgcgact
     7981 agtcgtgtat ttaatatgga aaaggaagaa ttggctcatc cgtcagtaag ttcattgttc
     8041 aaaaatcaag gaatttataa ggctctgcta ggagtctttc tcttgtatgt catttatttc
     8101 tcacagaatt tagaaattgt gactattttt gtcttatttg tgattggtgc tgcgacttac
     8161 ggctctttaa cagcggataa aaaaattatt ttgaaacaag gtggatcagc tattttggcc
     8221 ttgattagta ttttactctt taaatacact tgaaggtcga ttctaatctc gctaatcctt
     8281 tttaatccag aataagggaa atatgttata cttgttttta agaaaaaagt ctcattgaat
     8341 tggttttgag gagttagaaa tgaaagtatt agtgacaggt tttgagccct ttggagggga
     8401 aaagggcaat ccagctttgg aggccattaa aggtttacca gctgaaatcc atggtgctga
     8461 ggtccgttgg ctagaggtgc cgacagtttt tcacaaatct gctcaagtat tggaagaaga
     8521 gatgaatcgt tatcaacctg actttgtcct ttgtattggg caagctggtg gaagaactag
     8581 tttgacacct gaacgagtga ccattaatca agacgatgca tgcatttctg ataacgaaga
     8641 taatcaaccg attgaccgtc ccattcgccc agatggtgct tcggcctact ttagtagttt
     8701 gccgattaaa gcgatggttc aagctataaa aaaagagggc ttaccggcct ctgtttccaa
     8761 tacggcaggg acttttgtct gcagccattt gatgtatcag gctctctatt tggtagaaaa
     8821 gaaatctcca tatgttaagg caggttttat gcatattcct tatatgatgg aacaggtggt
     8881 gaacagaccg actactccag ctatgagttt agtggatatt cggcgaggga tagaagcagc
     8941 aatcggagct ataatagaac atggagatca ggaactcaag ttggtaggcg gagaaactca
     9001 ttgatagaaa aaagcttgag gagaaaaacc ttcaagcttt tggacgtttt cgggccaata
     9061 ctgctcggta aaacataatt ttagtgcatt ggatataagg taggagtgaa aaactagcaa
     9121 tgccaaaggt aatccaattg aggaagtacc aaggaagaag ctgtaaatct aggacaaagt
     9181 gctggaactt gtagcccttc ataaaggaac ggctagtttt taggattcgt cttggtggga
     9241 cctgtcctag gtctagacta taacagagaa gaaattccac ctgtgaatag gcataatact
     9301 gtggaatata gaggatattt cctacaatga tcaagatgag acttgcaaga aagtagagtc
     9361 caaagaccat gaggaaacgc tcggtttcaa ctgatgagag atctagattt ggaaactcag
     9421 gatgtagggt gacgaatttt ttggctaaaa agctactata aaagaggagg taaatcccaa
     9481 gtaaattagg gatactccat aaaaagagat agaaacgttt gagaagtagg gtcaaaaagg
     9541 tttgagaaaa gcgctcctca tcaaagagag ctaggctgtt ttttacagat ggctccgttt
     9601 tagaatcttt catgagtgtc agtgttgcat agacggaact ggtcaaaaga atagtcccga
     9661 taaaggagac tagtagagga aagaggtagg tttgaagtat ttggccaagt atgctgaaaa
     9721 atggctgttc taaaacagtc ccgtggatcc gagataaggg attaagaaaa ccagataaga
     9781 tgaccagcat actgggaagg atatagagga gaaagagacg gggggtgtca gcctgaaaat
     9841 gttttgactc ctgacgaatt gtttttaaat caatttttgg atagttcatt ctcttattat
     9901 accatagttc ttatacatag ttcgtgacag ttcctacttt ttttgataaa atcatacagt
     9961 gtgtccttgg gcacactgta tgaactggga ctgtctttcc cagcttcgga ggtaaaaaat
    10021 gtcagattca ccaatcaaat atcgtttgat taagaaagaa aaacacacag gagctcgtct
    10081 gggagaaatc atcactcccc acggtacctt tccgacacct atgtttatgc cagttgggac
    10141 acaagccact gtcaaaactc agtcacctga agaattgaag gagatgggtt cgggaattat
    10201 cctatcaaac acctatcatc tctggcttcg ccctggagat gaactcattg cacgcgctgg
    10261 tggtctccac aagttcatga attgggacca gcctatcttg acagatagtg gtggttttca
    10321 ggtttattct ttagcagata gccgtaatat cacagaagaa ggagtaacct ttaaaaatca
    10381 tctaaatggt tctaagatgt tcctatcccc agaaaaagcc atctctattc agaataatct
    10441 gggttcagac atcatgatgt cctttgatga atgtcctcag ttttatcaac cttatgacta
    10501 cgttaagaaa tcgatcgagc gtaccagccg ttgggctgag cgtggtttga aggctcaccg
    10561 tcgtccacat gaccaaggtt tgtttggaat tgtgcaaggt gcaggatttg aagaccttcg
    10621 ccgccaatca gctcatgatc ttgtcagcat ggatttctca ggctactcta tcggtggttt
    10681 ggcagtggga gaaacccatg aagagatgaa tgcggtcttg gactttacaa ctcaactgct
    10741 acctgaaaat aaacctcgtt atctgatggg tgtgggagcg ccagatagct tgatcgatgg
    10801 ggtcattcgt ggggtggata tgtttgactg tgtcttaccg actcgaattg ctcgtaacgg
    10861 gacttgtatg accagtcaag gacgtttggt tgtgaaaaat gcccagtttg ctgaggactt
    10921 tacgccactg gatcctgagt gtgactgcta cacatgtaat aactatacac gcgcttacct
    10981 tcgtcacctg ctcaaggctg atgaaacctt tggtatccgc ttgactagct accacaatct
    11041 ttacttcttg cttaacctga tgaagcaagt gcgacaagcc atcatggatg acaatctctt
    11101 ggaattccgt gagtattttg tggaaaaata tggctataat aagtcaggac gtaatttcta
    11161 aaatggaatt gatataaaaa aatcctaagt tttctcttag gatttttctt ctttttttga
    11221 tagaataaag tgtacaatga aaggaagaat aaactcgtat gcgcattaaa tggttttcct
    11281 tgattaggat tataggttta cttttggtac tcttgtatca cttctttcag acgatctttc
    11341 ctggaggatt tttcggggta gatgtctttt tcacattttc aggtttcctg attacagctc
    11401 tactcattga agaattttct aagaacaatg agattgattt gataggattt tttagaagac
    11461 gcttttatcg gattgtgcca cctgtggttt tgatggtctt ggtgaccatg ccttttactt
    11521 tcttggttcg ccaagactat gttgctggaa ttggtggcca gattgcgggc gtcttaggct
    11581 ttatgaccaa cttctatgaa ctcctaacag gtgggagtta tgaatctcag ttcattcctc
    11641 atttgtttgt tcataattgg agtttggcag ttgaggttca ctactatatt ctttggggat
    11701 tggcagtttg gttcttatcc aaacaagcta aatcaaatgg tcagttgaag gggatggtct
    11761 ttctcttatc tgctgctgcc ttcttgatca gtttcttctc catgtttatt ggtagttttc
    11821 tagtgacctc ttattcctct gtttatttct ccagtttaac tcatgtctat ccattctttt
    11881 tgggaagtat gttagcaact attgtaggtg ttcgtcagac gacttccctc gtcaagcagt
    11941 tggataaaat ctgggattta cgaaagactt tggtagtttt tggaggaggc tttggtttcc
    12001 tagttctttt gactttcttt gtcaaattca cttatctttt tgcctatctt atcggcttct
    12061 tgcttgccag tcttgcagct cttgccatga ttctggcggc gcgtgtctta catgaaaaga
    12121 cacatcatat acaggagccg aagattatca gctttttagc ggatactagc tatgcggttt
    12181 atcttttcca ttggcctttc tatatcattt tctcacagtt gacatcaaat cttcttgctg
    12241 tattactgac tctgatttgt tcttatggct ttgccagtct gtcattctat gtattggaac
    12301 cttggattgc aggcaagaac acacctattt tacaaactct tcgtcccctg ccttatattc
    12361 acgcaattct tgtagcaggt acaggaatct tgaccatcat tgtctgcacg gtgaccttgt
    12421 tggcaccaca agtgggagcg tttgagacag acttgactgt caatggcttg aagcaagctg
    12481 caacaaatat tggccagacc aaggtgatgg cagaacgggc agatgcaaac agtttgggaa
    12541 ttgctgatgg cactatgtta attggtgact cagtggcttt aagggcaaat acagcactac
    12601 agacagctct tcctggagca cagattaacg cgcaggtcag cgtaacaacc aagaccgcaa
    12661 atgaaatcat gctaaataat agccagaata aatttttacc taagacggtg gtcattgcga
    12721 ctggggtaaa taatcctgag aattacaagg atgactggga cagtatcgtg aaaaatcttc
    12781 ctaagggaca ccatatgatt ttggtgactc cttatgaggg agataagaca aaagagacct
    12841 atgccatcgt tgagaaggct gctgcctata tgagagaatt ggcagagaag acaccttaca
    12901 ttacgatagc agattggaat caagttgcga aagagcatcc agaaatttgg gctggaacag
    12961 accaggttca tttcgggagt gagagtagca ctatcgaagc aggagcaaaa ttgtatgcag
    13021 atacgattgc cacagctttg cagacagctc aagacaagcc gattaaatca aaataacttg
    13081 tattaaaaaa gagaagagtt ggagaaatcc agctctttta aaatatctcc aaaaaatagg
    13141 tctataccat ttacaaataa aaaagaaagg tttataatgt aattgacata ataaattgta
    13201 gaatcaatct tttaaggagg ttaacattat gcctaactat attaaagcgg atcagttttt
    13261 ctacccacac ggagttcgtc gaggtggtta cttggaactt gtggacggca agtttgggaa
    13321 acatgtagag cagattcctg aaggggctga ggtgattgac tatacaggtt atagcattgc
    13381 cccaggtctt gtggatactc atattcatgg atatgcaggt gtagatgtga tggacaacaa
    13441 cattgaaggt acattgcata ctatgagtga aggacttctt agtaccggtg ttaccagttt
    13501 cttacccaca actttaacag ccacttatga gcaattgctt gcagtcactg aaaatcttgg
    13561 aaaccattat aaagaagcaa caggtgctaa gattcgtggg atttattatg aaggtccata
    13621 tttcacagaa acttttaagg gggcacaaaa tccaacttat atgagagacc cgggtgttga
    13681 ggagtttcat tcttggcaaa aagcggcaaa tggcttgctt aataaaattg cccttgcacc
    13741 agaacgtgat ggggtggaag actttgttcg tacagttacg ggcgaaggtg tgacggttgc
    13801 tcttggacat tcaaacgcga cttttgatga agccaaaaaa gcagtcgatg ctggagcgag
    13861 tgtttgggtg catgcctata atggaatgcg tgggttgact caccgtgaat tgggtatggt
    13921 tggagccatg taccaattgc cacataccta tgcagagttg atctgtgatg gtcaccacgt
    13981 agatccaaag gcttgcgaaa ttcttatcaa acaaaaagga acagaaaaca tcgctcttat
    14041 cacagactgt atgacagctg ggggattgga agacggagat tatatgttgg gagaattccc
    14101 agttgtcgtt gcaaatggaa ctgcacgcct caaatcgaca ggtaacttgg caggttctat
    14161 cctcaaactc aaagatggtt tgaagaatgt ggtcgaatgg ggaattgcga atccgcatga
    14221 agcagtcatg atggccagct tcaacccagc taaatccgtt cacatcgatg acgtctgtgg
    14281 ccaaatccgt gaaggctacg acgctgactt catcgtatta gataaagatt tggaattggt
    14341 agcaacctat ctagatggcg taaaacgtta tcaagcataa gagagaaggc agaagttaga
    14401 gactagcttc tgctttttta tacagggtac tttactggta aataaaaagt taaaaaaatc
    14461 acaaaaaaag cttgaagaaa caaagaaaaa ggcttacaat tgaactataa atattacaaa
    14521 taaaaaaacg gaggagtgct ttatgaaagc ctatacttat gttaaaccag gacttgcttc
    14581 ttttgttgat gtagacaaac cagttattcg caagccaaca gacgctattg tgcgtattgt
    14641 aaaaaccact atttgtggaa cagacctcca tattatcaaa ggggatgttc ctacttgcca
    14701 aagtggtacc attcttggcc acgaagggat tgggattgtt gaagaagttg gggaaggagt
    14761 ttccaacttc aaaaaaggcg acaaggtctt gatttcttgc gtctgtgcct gtggtaaatg
    14821 ctactactgt aaaaaaggaa tttatgccca ctgtgaagac gaagggggct ggattttcgg
    14881 tcacttgatt gatggtatgc aggctgaata tctacgtgtc cctcatgcag ataatactct
    14941 ttaccatact ccagaagact tgtcagatga agctttggtt atgctgtcag acattctgcc
    15001 tactggatat gaaattggtg tcttaaaagg gaaagtagaa cctggttgca gcgtagccat
    15061 tattggttca ggtccagttg gattggctgc tcttttaaca gcccaattct attcaccagc
    15121 taaattgatt atggtagacc tagacgataa ccgcttggaa actgccctat cattcggtgc
    15181 gactcataag gttaattctt cagaccctga aaaagccatt aaagaaattt atgatttgac
    15241 agatggtcgt ggtgtggatg tcgctatcga agctgttggt attcctgcaa catttgattt
    15301 ctgtcaaaag attatcggtg tagacggaac ggttgccaac tgtggtgtgc atggtaaacc
    15361 agttgaattc gatttagata aactttggat tcgcaacatc aatgtaacaa ctggtttggt
    15421 atctacaaat acgactccac aattgttgaa agcacttgaa agtcataaga ttgaaccaga
    15481 aaaattggta actcactatt tcaaactcag tgaaattgaa aaagcctatg aagtcttcag
    15541 taaggcagca gaccaccatg ccattaaggt cattatcgaa aacgatatct cagaagccta
    15601 agtagtaaaa atatttttgt acataagtaa atagaaattc agtcatccat cagatggctg
    15661 gattttttat caaaaaatta agaaatgagc atatttcttt ccttgtctgg cggaattggt
    15721 tataatatac ggtacaaagg aatgaatgaa tatgtatcgt gttatagaaa tgtacggaga
    15781 ttttgaaccg tggtggttct tagaaggttg ggaagaagat attgtagcaa gtagaaaatt
    15841 tgaccagtat tatgatgctc tcaaatacta caaaacttgc tggtttagat tggaacaaga
    15901 atcccctctt tataaaagta gaagcgactt gatgaccatt ttttgggacc cggaagacca
    15961 acgctggtgt gatgaatgtg atgagtattt acaacaatac cattctttgg ctcttttgca
    16021 ggatgagcag gttatcccag acgaaaaact acgctcaggc tatgaaaaac aaaccagtca
    16081 ggaaaggaat cgttcttgcc gtatgaaatt aaaatagaga aaagtaactt ttttggagtt
    16141 gcttttttta tttttctaac gctttgcgaa tagtataggt gaggaggtaa gtatggttca
    16201 agaaattgca caagaaatca ttcgttcagc tcggaaaaaa gggacgcagg atatttattt
    16261 tgtccctaag ttagacgcct atgagcttca tatgagggta ggagacgagc gctgtaaaat
    16321 tggtagctat gattttgaaa agtttgcagc cgttatcagt cactttaagt ttgtggcggg
    16381 tatgaatgtg ggagaaaaaa gacgtagtca actgggttcc tgtgattatg cctatgacca
    16441 gaagatggcg tctctacgtt tatctactgt aggcgattat cgggggcatg agagtttggt
    16501 tatccgtttg ttgcacgatg aggagcagga cttgcatttt tggtttcagg atattgaaga
    16561 attaggcaag cagtacaggc aacggggact ctatcttttt gctggtccgg ttgggagtgg
    16621 taagacgacc ttgatgcatg aattgtccaa gtcactcttt aaaggacagc aagttatgtc
    16681 catcgaagat cctgtcgaaa tcaagcagga cgacatgctt cagttgcagt tgaacgaagc
    16741 aatcggccta acctatgaaa atctaatcaa actttccttg cgtcatcgac cagatctctt
    16801 gattatcgga gaaattcgtg acagcgagac ggcgcgtgca gtggtcagag ctagtttgac
    16861 aggtgcgaca gtcttttcaa ccattcacgc caagagtatc cgaggtgttt atgagcgtct
    16921 gctggagttg ggtgtgagtg aagaagaatt ggcagttgtt ctgcaaggag tctgctacca
    16981 gagattaatc gggggaggag gaatcgttga ctttgcaagc agagattatc aagaacacca
    17041 agcagccaag tggaatgagc aaattgacca gcttcttaaa gatggacata tcacaagtct
    17101 tcaggctgag acggaaaaaa ttagctacag ctaagcaaaa aaatatcatc accctattta
    17161 acaatctctt ttctagcggt tttcatctgg tggagactat ctccttttta gataggagtg
    17221 ctttgttgga caagcagtgt gtgatccaga tgcgtgcggg cttgtctcag gggaaatcat
    17281 tctcagaaat gatggaaagt ttgggatgtt caagtaccat tgtcactcag ttatctctag
    17341 ctgaagttca tggcaatctt cacctgagtt tgggaaagat agaagaatat ctagacaatc
    17401 tggccaaggt caagaaaaag ttaattgaag tagcgaccta tcctttgatt ttgctgggtt
    17461 ttcttctctt aattatgctg gggctacgga attacctgct cccacaactg gatagtagca
    17521 atattgccac ccgaattatc ggtaatctgc cacaaatttt tctaggcatg gtagggcttg
    17581 tttccgtgct tgccctttta gcactaactt tttataaaag aagttctaag atgagtgtct
    17641 tttctatctt agcacgcctt ccctttattg gaatctttgt gcagacctac ttgacagcct
    17701 attatgcacg tgaatggggg aatatgattt cacagggaat ggagctgacg cagatttttc
    17761 aaatgatgca ggaacaaggt tcccagctct ttaaagaaat cggtcaagat ctggctcaaa
    17821 ccctgaaaaa tggccgtgaa ttttctcaga cgataggaac ctatcctttc tttaggaagg
    17881 aattgagtct catcatagag tatggggaag ttaagtccaa gctgggtagt gagttggaaa
    17941 tctatgctga aaaaacttgg gaagcctttt ttacccgagt caaccgcacc atgaatttgg
    18001 tgcagccact ggtttttatc tttgtggcac tgattatcgt tttactttat gcggcaatgc
    18061 tcatgcccat gtatcaaaat atggaggtaa atttttaaaa tgaaaaaaat gatgacattc
    18121 ttgaaaaaag ctaaggttaa agcttttaca ttggtggaga tgttagtagt cttgctgatt
    18181 atcagcgtgc ttttcttgct ctttgtacct aatctgacca agcaaaaaga agcagtcaat
    18241 gacaaaggaa aagcagctgt tgttaaggtg gtggaaagcc aggcagaact ttatagcttg
    18301 gataaaaatg aagatgctac tctgagcaag ttacaaggag atgggcgcat cacggaagaa
    18361 caggttaaag cttataatga atactatact aaaaatggag gggcaaatcg taaagtcaat
    18421 gattaaggcc tttaccatgc tggaaagtct cttggttttg ggacttgtga gtatccttgc
    18481 cttgggctta tccagctctg tccagtccac ttttgcagca gtagaggagc agattttctt
    18541 tatggagttt gaagaactct atcgggaaac ccaaaaacgc agtgtagcca gtcagcaaaa
    18601 gactagtcta aatttagatg ggcagacgct tagcaatggc agtcaaaagt tgacagttcc
    18661 taaaggaatt caggcaccat caggccaaag tattacattt gaccgagctg ggggcaattc
    18721 gtccctggct aaggttgaat ttcagaccag taaaggagcg attcgctatc aattatatct
    18781 aggaaatgga aaaattaaac gcattaagga aacaaaaaat tagggcagtg attttactgg
    18841 aagcagtagt cgctctagct atctttgcca gcattgcgac cctccttttg ggacaaattc
    18901 aaaaaaatag gcaagaggaa gcaaaaatct tgcaaaagga agaagtcttg agggtagcta
    18961 agatggccct gcagacgggg caaaatcagg taagcatcaa cggagttgag attcaggtat
    19021 tttctagtga aaaaggattg gaggtctacc atggttcaga acagttgttg gcaatcaaag
    19081 agccataagg tcaaggcttt taccttgtta gaatccctgc ttgccctcat tgtcatcagt
    19141 gggggattac tcctttttca aactatgagt cagctcctca tttcagaagt tcgctaccag
    19201 caacaaagcg agcaaaagga gtggctcttg tttgtggacc aacttgaggc agaattagac
    19261 cgttcgcagt tcgaaaaagt agaaggcaat cgcctataca tgaagcaaga tggcaaggac
    19321 atcgccatcg gtaagtcaaa gtcagacgat tttcgtaaaa ccgatgctag tggacggggg
    19381 tatcagccta tggtttatgg cctcaaatca gctcagatta cagaggacaa tcaactggtt
    19441 cattttcgtt tccagtttca aaaaggctta gaaagggagt tcatctatcg tgtggaaaaa
    19501 gaagaaagtt aaggcaggtg ttctcctcta cgcagtcacc atagcagcca tctttagtct
    19561 tttgttgcaa ttttatttga accgacaaat cgcccactat caagactatg ctttaaataa
    19621 agaaaaattg gttgcttttg ccatggctaa acgaaccaag gataaagccg agcaagaaag
    19681 tggggaacag gtttttaatc taggtcaggt aagctatcaa aacaagaaaa caagcttggt
    19741 gacgactgtt cgtacgtcta agagccaata tgagtttctg tttccttcag tcaaaatcaa
    19801 agaagagaaa agagataaaa aggaagaggt agcgaccgat tcaagcgaaa aagcggagaa
    19861 aaaaaatcag aagagaagcc tgaaaagaaa gagaattcct agtcaattca actataatgc
    19921 gttgaatcca gaatagtcca ctgtagtttc tagaaaattg ctggaaatgg atgttaagct
    19981 ccaattcatt tgtttatatc ttatttcagt ttactatact ttgtgctaaa ctaaagatat
    20041 gaaacatgat tttaaccaca aagcagaaac tttcgactcc cctaaaaata tcttcctcgc
    20101 aaacttggta tgtcaagcag tcgagaaaca gattgatatt ttatcagaca aagtaatttt
    20161 agatttcggt ggtggcacgg gtctattagc cttgccccta gccaagcagg ctaagtcagt
    20221 tactcttgta gacatttctg agaaaatgtt ggagcaagct cgtttgaaag tggagcagca
    20281 agcaatcaag aatatccagt ttttggagca agatttaccg aaaaatccct tggagaaaga
    20341 gtttgattgc cttgctgtta gtcgggttct tcatcatatg cctgatttgg atgcggcttt
    20401 ctcactgttt catcaacatt tgaaggaaga tgggaaactc atcattgctg attttaccaa
    20461 gacagaagct aatcatcatg gatttgattt agctgaactg gaaaacaagc taattgagca
    20521 tggtttttca tctgtgcata gtcagattct ctatagcgct gaagacctgt ttcaaggaaa
    20581 tcactcagaa ttctttttaa tagtagccca aaaatcactc gcctagtcag ggagtgattt
    20641 ttctataagg atggaaaaaa gaagggaaat ttgataagat aggaatatgg attttgaaaa
    20701 aattgaacaa gcttatacct atttactaga gaatgtccaa gttatccaaa gtgatttggc
    20761 gaccaacttt tatgacgcct tggtggagca aaacagcatc tatctggatg gtgaaactga
    20821 gctaaaccag gtcaaagaca acaatcaggc ccttaagcgt ttagcactac gcaaagaaga
    20881 atggctcaag acctaccagt ttctcttgat gaaggctggg caaacagaac ccttgcaggc
    20941 caatcaccag tttacaccag atgccattgc tttgcttttg gtgtttattg tggaagagtt
    21001 gtttaaagag gaggaaatta ctatcctcga aatgggttct gggatgggaa ttctaggcgc
    21061 tactttcttg acctcgcttg ataaaaaggt ggattacttg ggaatggaaa tggatgattt
    21121 gctgattgat ctggcagcta gcatggcaga tgtaattggt ttgcaggctg gctttgtcca
    21181 aggagatgcc gttcgtccac aaatgctcaa agaaagcgat gtggtcatca gtgacttgcc
    21241 tgttggctat tatcctgatg atgccgttgc gtcgcgccat caagttgctt ctagccaaga
    21301 acatacttac gcccatcact tgctcatgga acaagggctt aagtacctca agtcagacgg
    21361 atacgctatt tttctagctc cgagtaattt gttgaccagt cctcaaagtg atttgttaaa
    21421 agaatggctg aaagaagagg cgagtctggt tgctatgatt agtctgcctg aaaatctctt
    21481 tgctaatgcc aaacaatcta agactatttt tatcttacag aagaaaaatg aaatagcagt
    21541 agagcctttt gtttatccac ttgctagctt gcaagatgca agtgttttaa tgaaatttaa
    21601 agaaaatttt caaaaatgga ctcaaggtac tgaaatataa aatagatttt gttataatag
    21661 ttgaaaacgc ttaaaaaggg gtatcatgtt atgacaaaaa caattgcaat caatgcagga
    21721 agttcaagtt tgaaatggca attatactta atgccagaag aaaaagtgtt agccaaaggt
    21781 ttgattgaac gtatcggttt gaaagattca atttcaactg taaaatttga cggccgttct
    21841 gaacaacaaa ttttggatat tgaaaatcat acacaagccg ttaaaatttt attggatgac
    21901 ttgattcgtt tcgatattat caaggcttat gacgagatta caggtgttgg acatcgtgtt
    21961 gttgctggtg gagaatattt caaagaatca acagttgttg agggagatgt tttagaaaaa
    22021 gttgaagagt tgagtttgtt ggctcctcta cacaacccgg ccaatgcagc aggtgttcgt
    22081 gccttcaagg aattgttgcc agacattacc agtgtagttg tttttgatac ttccttccac
    22141 acaagtatgc cagagaaagc ttatcgctac cctctaccaa caaaatatta cacagaaaac
    22201 aaggttcgta aatacggtgc tcatggtaca agtcaccagt ttgtagcagg agaagctgca
    22261 aaactcttgg gacgtccatt agaagacttg aagttaatta cctgtcatat tggtaacgga
    22321 ggctcaatta cagctgtgaa agccggcaaa tctgtagaca cttctatggg gttcactcct
    22381 cttggtggta ttatgatggg aacgcgtaca ggggatattg atccagctat cattccttat
    22441 ttaatgcaat atacagagga ttttaacaca ccagaagata tcagtcgtgt tcttaaccgt
    22501 gaatcaggtc ttttgggagt ttctgctaat tctagcgata tgcgcgatat agaagcagct
    22561 gtagcagaag ggaatcacga ggctagcttg gcttatgaaa tgtatgttga ccgtatccaa
    22621 aaacatatcg gtcagtactt tgcagtgcta aatggagcag atgccattgt tttcacagca
    22681 ggtgtcggtg aaaatgcaga gaatttccgt cgtgatgtaa tctcagggat ttcgtggttt
    22741 ggttgtgatg ttgatgatga aaagaatgtc tttggcgtta caggagacat ctcaacagag
    22801 gcagctaaaa tccgtgtctt ggttattcca acagatgaag aattagtcat tgcccgtgac
    22861 gttgaacgct tgaaaaaata agtgaaacta aaaaaatatt caatacaagg agttgggaaa
    22921 gttatttttc cagcttcttt ttctgatgaa attgtccaaa accttgctat gattggcttt
    22981 tttgaaaaat atggtataat agtagtaatt taatagatgg agttgagttt tgaagaaaaa
    23041 ctttcgtgta aaaagagaga aagattttaa ggcgattttc aaggagggga caagttttgc
    23101 taatcgcaaa tttgtggtct accaattaga aaaccagaaa aaccattttc gagtaggtct
    23161 atcagttagc aaaaaactgg ggaatgccgt cactagaaat caaattaagc gacggattcg
    23221 gcatattatc cagaatgcaa aagggagtct ggtagaagat gtcgactttg ttgtcattgc
    23281 tcgaaaagga gtcgaaacct tgggatacgc agagatggag aaaaatctac tccatgtatt
    23341 aaaattatca aagatttacc gggaaggaaa tgggagtgaa aaagaaacta aagttgacta
    23401 gtttgctagg actgtctctg ttaatcatga cagcctgtgc gactaatggg gtaactagcg
    23461 atattacagc cgaatcggct gatttttgga gtaaattggt ttacttcttt gcgaaaatca
    23521 ttcgcttttt atcgtttgat attagtatcg gagtggggat tattctcttt acggtcttga
    23581 ttcgtacagt cctcttgcca gtctttcagg tgcaaatggt ggcttctagg aaaatgcagg
    23641 aagctcagcc acgcattaag gcgcttcgag aacaatatcc aggtcgagat atggaaagca
    23701 gaaccaaact agagcaggaa atgcgtaaag tatttaaaga aatgggtgtc agacagtcag
    23761 attctctttg gccgattttg attcagatgc cggttatttt ggccttgttc caagccctat
    23821 caagagttga ctttttaaag acaggtcatt tcttatggat taaccttggt agtgtggata
    23881 caacccttgt tcttccgatt ttagcagcag tattcacctt tttaagtact tggttgtcca
    23941 acaaagcttt gtctgagcga aatggcgcta cgactgcgat gatgtatggg attccagtct
    24001 tgatttttat ctttgcagtt tatgcgccag gtggagtcgc cctatactgg acagtgtcta
    24061 atgcttatca agtcttgcaa acctatttct tgaataatcc attcaagatt atcgcagagc
    24121 gcgaggccgt agtacaggca caaaaagatt tggaaaatag aaaaagaaaa gccaagaaaa
    24181 aggctcagaa aacgaaataa ataaggagga atctggtaat ggtagtattt acaggttcaa
    24241 ctgttgaaga agcaatccag aaaggattga aagaattaga tattccaaga atgaaggctc
    24301 atatcaaagt catttctagg gagaaaaaag gctttcttgg tctatttggt aaaaaaccag
    24361 cccaagtgga tattgaagcg attagtgaaa cgactgttgt caaagcaaat caacaggtag
    24421 taaaaggcgt tccgaaaaaa atcaatgatt tgaacgagcc tgtgaagacg gttagtgaag
    24481 aaaccgttga ccttggtcat gtggttgatg ctattaaaaa aatagaggaa gaaggtcaag
    24541 gtatttctga tgaagtcaag gctgaaatct taaaacatga aagacatgcc agcactatct
    24601 tagaagaaac tggtcacatt gagattttaa atgaacttca aatcgaggaa gcgatgaggg
    24661 aagaagcagg cgctgatgac cttgaaactg agcaagatca aactgaaaat caagacttga
    24721 aagagatggg cttgaaggtc gagcaaagtt atgatattgc ccaggtggct acggatgtga
    24781 ctgcctatgt tcaagcgatt gtggatgaca tggatgttga agctacactt tcaaatgatt
    24841 ataaccgtcg tagcatcaat ctacaaattg acaccaacga accaggtcgt attatcggct
    24901 accatggtaa agtcttgaag gccttgcaac tgttggctca aaattatctt tacaaccgct
    24961 attccaaaac cttctacgtt acaatcaatg tcaatgatta tgtcgaacac cgtgcagaag
    25021 tcttgcagac ctatgcgcaa aaattggcga ttcgtgtttt agaagaagga cgtagtcatc
    25081 aaacagatcc aatgtcgaat agtgaacgca agattatcca ccgtattatt tcacgtatgg
    25141 atggcgtgac cagttactct gaaggtgatg agccaaatcg ctatgtcgtt gtagatacag
    25201 aataagtaaa atcagggttg acctgatttt ttgctagcta gaggaggtta aactgatgtt
    25261 gaataagata agagactatt tagactttgc tggtttgcag taccgtaatc ctgataaagc
    25321 gggagcagag cgagagaaga tgctggcatt ccgccacaaa ggacaagagg cccgaaaggc
    25381 ttttacagaa ctggccaaag cctttcaagc aagccatcca gaatggcaac tccaacagac
    25441 tagtcagtgg atgaatcagg cccagcgttt gagaccacat ttttgggttt atctacagag
    25501 agacggacaa gtgacagaac ctatgatggc cttacgtttg tatgggacat ctactgactt
    25561 tggaatttct ttggaagtca gtttcatcga acgtaagaag gatgagcaaa cactgggcaa
    25621 gcaggccaaa gttttagaca ttccaaccgt taaagggatt tattatctaa cctactctaa
    25681 tggtcaaagt caacggtggg aggcgaatga agaaaagcgt cgtactttac gcgagaaggt
    25741 gagaagtcaa gaagttcgaa aagttttagt gaaggtagat gttcctatga cagaaaattc
    25801 gtctgaagaa gaaatcgtag aaggcttatt gaagtcttat tctaaaattc ttccctatta
    25861 tctagctacg agaaaataag ataatttgta aaacatcata aatcatacag tccaagagtg
    25921 aacagtccgc tgtgtaattc ttggtctttt tgtttgcgct ttcgcattat ataataaact
    25981 tacaaaaaca attcaaaagg agaacaatta tggaagtcgt ttcaagtgtt ctaaattggt
    26041 tttctagcaa tattttgcag aatcccgcat ttttcgtagg tttattggtg ttgataggat
    26101 atgcactttt gaaaaaacct gcccatgacg ttttttcagg gtttgttaaa gcaacagtag
    26161 ggtatatgtt gcttaacgtg ggtgctggtg gtttggttac aacctttcgt ccaatcttag
    26221 cagctcttaa ctacaaattc caaattggtg cagcggttat cgacccttac tttggacttg
    26281 ctgcagcaaa caacaaaatt gcagcagagt ttccagattt tgttggaact gcaactacag
    26341 ctctattgat tggttttgga ataaatatct tgctcgtagc tcttcgaaag attacgaagg
    26401 taagaaccct ctttattact ggtcacatca tggtacaaca agctgcaaca gtatctctta
    26461 tggttctatt cttagtacca caattgcgca atgcttacgg tacagcagcg attggtatca
    26521 tctgtggact ttactgggca gttagttcaa atatgactgt tgaggcaact caacgcttga
    26581 ctggtggtgg cggatttgcg attggtcacc aacagcaatt tgcaatctgg tttgtagata
    26641 aagtagcagg acgctttggt aagaaagaag aaagtttaga caatcttaaa ttacctaagt
    26701 tcctctcaat cttccacgat acagttgttg catctgctac cttgatgctc gtattcttcg
    26761 gggccattct tttaatcttg ggtccagaca ttatgtctaa taaagaagtc atcacttcag
    26821 gaactctatt caatcctgct aaacaagatt tctttatgta cattatccaa acagccttta
    26881 ccttctcagt ttacttgttc gttttgatgc aaggtgtccg aatgttcgta tctgagttga
    26941 caaacgcctt ccaaggtatt tcaaacaaat tgttgccagg ttcattccca gcggttgacg
    27001 ttgcagcttc ttatggattt ggttctccaa atgctgtctt gtcaggattt acctttggtt
    27061 tgattggtca attgattaca attgtcttgc tcatcgtctt taaaaatccg attcttatta
    27121 ttacaggatt tgtaccagtg ttctttgaca atgcagccat tgcggtctac gctgataaac
    27181 gcggcggatg gaaagcggct gttatccttt cctttatatc aggtgtcctt caagttgctc
    27241 taggagctct ttgtgtggcc cttctcgatt tggcatctta tggtggctac catggaaata
    27301 tcgactttga attcccatgg cttggatttg gatatatctt caaatacctt ggtattgttg
    27361 gttatgtact tgtgtgtctc ttcttgcttg ttattcctca acttcaattt gccaaagcaa
    27421 aagataaaga gaaatattac aacggtgaag ttcaagaaga agcttagtat ctagaaaagg
    27481 agaaataaaa tggttaaagt attagcagcg tgcggaaatg gaatgggttc atcaatggtt
    27541 atcaagatga aggttgaaaa tgctctccgt aagcttaatc aaacagattt tacagtcaat
    27601 tcatgcagtg tcggtgaagc taaaggttta gcagtaggat atgacatcgt aatcgcttct
    27661 cttcatttga ttcaagaatt ggaagggcga actaatggga agttaattgg acttgataac
    27721 ttgatggatg ataaagaaat caccgaaaaa ctcagtcaag cactacagta aaaggttgga
    27781 gggggctgga cagaaactga gagttatcgt ttctgtcctt ctccctcttt aaataaagga
    27841 ggcagatatg aatttaaaac aagctttaat tgacaatgac tcgatccgac taggtttaga
    27901 ggctaacaat tggaaagaag cagtcaaggt agcagtagat cccttaattg aaagtggggc
    27961 aattttgcca gagtattacg atgctatcat tgaatcgact gaagagtatg ggccttacta
    28021 tatcttgatg ccaggtatgg ctatgcccca cgctagacct gaagctggtg tgcaaagtga
    28081 tgccttttca ttgattacct tacaaaatcc tgttgtattt tcagatggga aagaggtatc
    28141 tgttttgttg gcactagcag caacaagctc aaaaattcac acaagtgtag ccattccaca
    28201 aattattgcc ctgtttgaat tagaagattc tattgcacgt ttacaggctt gccagactaa
    28261 agaagatgtc ttggctatga ttgaagaatc taaggatagc ccttatctcg aaggattgga
    28321 tttggaaagt tagaaagagg aataaagaaa tgacaaaaag aatacctaat ttacaagttg
    28381 cattagacca ttcagacttg caaggagcga ttaaagcagc tgtttctgtt ggtcaggaag
    28441 tagatattat cgaagctgga actgtttgct tgcttcaagt tggaagtgaa ctggctgaag
    28501 tcttgcgtag ccttttccca gataagatta ttgtggcaga cacaaaatgt gctgatgctg
    28561 gtggaacagt tgctaaaaat aatgcggttc gtggagcaga ctggatgact tgtatctgtt
    28621 gtgcaaccat ccctactatg gaagcagctc taaaggctat caagactgaa cgaggagaac
    28681 gaggcgaaat ccagatcgag ctttatggcg attggacttt tgaacaagct cagctttggc
    28741 tagatgcagg tatctcacaa gctatttatc accaatctcg tgatgctctt cttgctggtg
    28801 aaacttgggg tgaaaaagac cttaataagg ttaaaaaact cattgacatg ggcttccgtg
    28861 tatctgtaac aggtggtcta gatgtagata ctctcaaact ctttgaaggt gttgatgtct
    28921 ttacctttat cgcaggtcgt ggaattacag aggctgcgga tccagcagga gcagcgcgtg
    28981 ccttcaagga tgaaatcaaa cgaatttggg ggtaaatcat ggtacgtcca attggaattt
    29041 atgaaaaggc aaccccaaca cactttactt ggctagaacg tttaaatttt gccaaggagt
    29101 taggctttga ttttgtcgag atgtctattg acgaacgtga cgagcgttta gcaagacttg
    29161 actggagtaa ggaagaacgc ttggaagttg tcaaagcaat ctatgaaact ggtgttcgta
    29221 ttccttctat ctgtttttca ggccatcgtc gctacccatt gggttcaaaa gatccagttc
    29281 tagaggaaaa atctctagaa ctcatgaaaa aatgtatcga attagctcaa gacttgggag
    29341 ttcgtacgat tcaattagct ggttacgatg tttactatga ggaaaagtca ccccagacac
    29401 gccaacgttt tatcaaaaat ttgagaaaag cctgtgactg ggctgaagaa gctcaggtgg
    29461 tacttgctat tgaaattatg gatgatcctt tcatcaatag catcgaaaaa tatttggcta
    29521 tagaaaaaga gattgactct cccttcctct ttgtatatcc agatattggt aatgtgtctg
    29581 catggcataa tgatatctat agtgagtttt atcttggtca tcatgccatc gcagctctcc
    29641 atctcaagga tacttatgca gtgacagaaa gttcaaaggg ccagttccga gatgtacctt
    29701 tcgggcaagg ttgtgtcaaa tgggaagaag ctttcgatat tttaaaggaa accaattata
    29761 atggaccttt cctaatcgaa atgtggtctg aaaattgtga aacagtagaa gaaacacgcg
    29821 cagccattca agaggcgcaa gcttttctct atccactcat taagaaagca ggtttgatgt
    29881 aagatgaatc aagtaatcaa tgctatgcgt aaacgagtct gtgatgccaa tcaatcattg
    29941 ccaaaacatg gacttgtcaa atttacctgg gggaatgtat ctgaagttaa tcgcgaactc
    30001 ggtgtcattg ttatcaaacc atcaggcgtg gattatgacg aattgacacc tgaaaacatg
    30061 gtagtgactg atctagatgg taagatccta gaaggggatt taagaccatc ttccgacctc
    30121 ccaactcatg tgcaattata taaggcttgg tcagaaattg gtagtgtggt tcacacccat
    30181 tcgacagaag ctgttggttg ggctcaggca ggtcgtgata ttcctttcta cggaacaacc
    30241 catgcagatt atttctacgg ttcaatccct tgcgcccgta gtttgaccaa ggacgaagta
    30301 gaagtggcct atgaaaaaga tactggcctg gttatcgtag aagagtttga acatcgcgga
    30361 cttaacccgg ttgaagtacc aggaattgtt gtacgcaatc acggtccatt cacctggggc
    30421 aaaaatccag agaatgctgt ttatcactct gtcgtactag aggaagtatc aaagatgaat
    30481 cgctttacag aacaaatcaa tccaagagtt ggacctgctc cccagtacat actagaaaaa
    30541 cactaccaac gtaaacatgg accaaatgct tattatggtc aaaagtaaga acgatgaagg
    30601 aggagaaaaa gataaattta gctcctcttt ttacatttga tttttattga gagtaaagtt
    30661 ggaattgaag taattttaaa agatttttta gaaatagcgc ttgatatata tatggtaaaa
    30721 taaaaagaat tgctgtgata tcaatagatt tgggggattt tttaatatgg tactggataa
    30781 ggcaagttgt gatttgcttc aatatttgat ggatcaagaa acgtccaaaa cgattatggc
    30841 gatttcgaaa gatttgaaag agtcaagaag gaaaatttat tatcacattg acaaaatcaa
    30901 tgctgctctg gttgacgagg cgcttcacat cattagtatt ccacgaattg gtattcactt
    30961 aacggaagag cagagagatg cttgttgtaa actattatcg gaagtagatt cgtacgatta
    31021 tatcatgagt gcgcatgaac gtatgatgat aatgttacta tggataggta tttctaaaga
    31081 acgtattacg attgaaaaat tgatagagtt aacagaggta tctaggaata ctgttctcaa
    31141 tgatttgaat agtattcgtt atcaactaac tttggaacaa tatcaggtga tcttgcaagt
    31201 gagcaagtca cagggatacc accttcatgc ccaccctctt aataaaattc agtatcttca
    31261 atcgcttcta tatcatattt ttatggaaga aaatgccact tttgtatcta ttttagaaga
    31321 taagatgaaa gagaggttag atgatgagtg tttgctttct gttgaaatga accaattttt
    31381 taaggaacag gttcctttag ttgaacaaga tttagggaag aaaataaacc atcatgaaat
    31441 aacttttatg ttgcaggttc taccttattt gctgttaagc tgtcataatg ttgaacagta
    31501 tcaagaaaga catcaggata tagagaaaga attttctttg ataagaaaaa gaatagagta
    31561 tcaggtgtct aagaaattag gagaacggtt gtttcaaaag tttgaaattt ctttgtcagg
    31621 acttgaagtt tctcttgtag ctgttctcct cctctcctat cgtaaggatt tggatattca
    31681 tgcagaaagt gatgattttc ggcaattaaa acttgcttta gaagaattta tctggtattt
    31741 tgaatcacaa atccgaatgg agattgagaa caaggatgat ttgttacgaa atttgatgat
    31801 ccactgtaaa gccttgttat ttagaaagac ttacggtatt ttttctaaaa atcctctaac
    31861 aaaacaaatt cgatccaagt atggagaatt atttttagtc actagaaaat ctgcggaaat
    31921 tttagaagga gcatggttta ttcggctaac agacgatgat attgcctatt tgacgattca
    31981 tattggagga tttttaaagt atacaccatc gtctcaaaaa aatatgaaaa aagtttatct
    32041 cgtttgtgat gaaggtgttg cggtttcgag acttttgctg aaacaatgca aactttattt
    32101 tccaaatgag caaattgaca ctgtatttac aacagaacaa tttaagagtg tggaagatat
    32161 tgcacaagtt gatgtagtga ttactactaa tgatgatttg gatagcagat ttccgatttt
    32221 aagggttaat cctatccttg aagcagaaga tattttgaaa atgctagact atcttaaaca
    32281 caatatattt cgtaataaga gcaaaagttt cagtgaaaat ctttctagtc ttatttcgtc
    32341 ttatattgta gacagcaagt tggctagtaa gttccaagaa gaggttcaaa cacttataaa
    32401 taaagaaata gtagttcaag cttttttgga agatatttga aggacagtcc aatgatgaac
    32461 acaaacctgt gtttttcttg gtctttttta gtgttttgaa gggtggtata ctaatctcaa
    32521 agataacaat tatatccaaa ggaggcaaca tatgccaaac gtcaaagaaa ttacaagaga
    32581 gtcatggatt ttagccactt tcccagagtg gggaacatgg ttgaacgaag aaatcgaaga
    32641 agaagtcgta cctgaaggca actttgccat gtggtggcta ggcaactgtg gtacttggat
    32701 taagacacca gctggtgcta acgttgtcat ggacctttgg tcaaaccgtg gaaaatcaac
    32761 caaaaaagtg aaagatatgg ttcgtgggca ccaaatggca aatatggcag gtgttcgtaa
    32821 gttgcaacca aacttgcgtg ttcagccaat ggttatcgat ccatttgcta tcaacgaact
    32881 agactattac ttagtttcac acttccacag tgatcatatc gacccataca cagctgcagc
    32941 aattctcaac aatcctaagt tagagcatgt taagtttatc ggtccttacc actgtggacg
    33001 aatctgggaa ggatggggtg ttccaaaaga acgtatcatc gttgttaaac caggtgacac
    33061 tatcgaatta aaagatatga agattcatgc agtagaatca tttgaccgta cttgcttggt
    33121 aactctccca gtgaacggtg ctgatgagac aggcggtgaa cttgctggct tggctgttac
    33181 agatgaagaa atggctcaaa aggctgttaa ctatatcttt gaaacaccag gtggaaccat
    33241 ctatcatggt gcagattctc acttctcaaa ctattttgca aaacatggta aagactttaa
    33301 aattgatgtt gctttgaata actatggtga aaatccggta ggtatccaag acaaaatgac
    33361 atctatcgat cttcttcgta tggcagaaaa tctgcgtacc aaagtcatta tcccagttca
    33421 ctatgatatc tggtctaact tcatggcttc tactaatgag attctagaac tttggaaaat
    33481 gcgaaaagat cgcttgcaat acgatttcca tccatttatc tgggaagttg gcggtaagta
    33541 cacttatcct caagatcaac acttagtaga ataccatcat ccacgtggtt ttgatgattg
    33601 ttttgaacaa gactctaaca ttcaatttaa agctttgcta taatataaaa atattctttg
    33661 gaggttatcc gtatgttgca tgatacggat aattttcata taatagtaaa atagaatgtg
    33721 tgattcaata atcacctcaa atagaaagga aattctatgt caaatctatc tgttaatgca
    33781 attcgttttc taggtattga cgccattaat aaagccaact caggtcatcc aggtgtggtt
    33841 atgggagcgg ctccgatggc ttacagcctc tttacaaaac aacttcatat caatccagct
    33901 caaccaaatt ggattaaccg cgaccgcttt attctttcag caggtcatgg ttcaatgctc
    33961 ctttatgctc ttcttcacct ttctggtttt gaagatgtca gcatggatga gattaagagt
    34021 ttccgtcaat ggggttcaaa aacaccaggt cacccagaat ttggtcatac ggcagggatt
    34081 gatgctacga caggtcctct agggcaaggg atttcaactg ctactggttt tgcccaagca
    34141 gaacgtttct tggcagccaa atataaccgt gaaggctaca atatctttga ccactatact
    34201 tacgttatct gtggagacgg agacttgatg gaaggtgtct caagcgaggc agcttcatac
    34261 gcaggtttgc aaaaacttga taagttggtt gttctttatg attcaaatga tatcaacttg
    34321 gatggtgaga caaaggattc ctttacagaa agtgttcgtg accgttacaa tgcctacggt
    34381 tggcatactg ccttggttga aaatggaaca gacttggaag ccatccatgc tgctatcgaa
    34441 acagcaaaag cttcaggcaa gccatcttta attgaagtga agacggttat tggatatggt
    34501 tctccaaaca aacaaggaac taatgctgta cacggcgccc ctcttggagc agatgaaacc
    34561 gcatcaactc gccaagccct cggttgggac tacgaaccat ttgaaattcc agaacaagta
    34621 tatgctgatt tcaaagaaca tgttgcagac cgtggcgcat cagcttatca agcttggact
    34681 aaattagttg cagattataa agaagctcat ccagaactgg ctgcagaagt agaagccatc
    34741 atcgacggac gtgatccagt cgaagtgact ccagcagact tcccagcttt agaaaatggt
    34801 ttttctcaag caactcgtaa ttcaagtcaa gatgccttga atgttgtggc agctaaatta
    34861 ccaaccttcc taggtggatc agctgacctt gctcactcaa acatgactta tatcaagacg
    34921 gatggacttc aagacgatac caatcgcttg aatcgtaaca ttcagtttgg tgttcgtgaa
    34981 tttgcaatgg gaacaatctt gaacgggatg gcccttcatg gtggacttcg tgtatacggt
    35041 ggaactttct tcgtcttctc tgactatgtg aaggcagctg tccgcttgtc agccttacaa
    35101 ggacttcctg tgacttatgt ctttacccat gattcaatcg cagttgggga agatggtccg
    35161 actcacgaac cagttgagca tttagcaggt cttcgtgcta tgccaaatct aaatgttttc
    35221 cgtccagcag atgcgcgtga aacgcaagca gcttggtacc ttgcagtgac aagtgagaaa
    35281 acaccaactg cccttgtctt gacacgtcaa aacttgactg ttgaagatgg aacagacttc
    35341 gacaaggttg ctaaaggtgc ttatgttgta tatgaaaatg cagccgactt tgataccatc
    35401 ttgattgcga caggttcaga ggttaatctt gctgtctcag ctgctaaaga attggctagt
    35461 caaggcgaaa aaatccgcgt agtcagcatg ccatctacag atgtctttga taaacaagat
    35521 gcagcttaca aggaagagat tcttccaaat gcagtccgcc gtcgtgttgc agtcgaaatg
    35581 ggtgcaagtc aaaactggta caaatatgtt ggtctcgatg gtgccgttct aggtattgat
    35641 accttcggag cctctgcccc agcaccaaaa gtattggcag aatatggctt tactgtagaa
    35701 aatcttgtaa aaattgttcg aaacttgaaa taatcctaaa aatcagggcg taagctctgg
    35761 tttttcttac cagaaaagta aggtacaatc ttgtaaaagt agctgaaatt tgatatagta
    35821 gtcctatgta aaagacaaag gagaaaacaa tgaatccaaa tattactttt ttaatcatgc
    35881 ttgtaggtat gatggccttg atgttcttta tgcaacgttc tcaaaagaaa caagctcaaa
    35941 agcgtatgga aagcttaaat aaactacaaa aaggctatga agtgattaca atcggtggac
    36001 tttatggaac agtcgatgaa gtagatacgg agaagggaac aatagttctt gacgtagatg
    36061 gagtttactt gacttttgaa ctagctgcta tcaagacagt attaccgctg aaagaaacag
    36121 cttcactaga aggcgcaatt gaaaaataag acgggatcac gaactcccgt ttttctataa
    36181 aagaaaggaa atgggatgaa aaaattagtc tttgtctgtc tgggaaatat ttgccgtagc
    36241 cctatggccg agtttgttat gaaatcaatg acagataact acgaaatcca aagtcgagca
    36301 acttcctctt gggaacatgg caatccgatt cataagggga ctcagggaat ttttcaagag
    36361 tatgagattc cttatgacaa gaacaagaca tcgcttcaga ttagtaagga agattttgaa
    36421 gcctttgatt atattatcgg aatggacgct tcaaatattt ctgacttatg tcagatgtgt
    36481 ccagtagact gtcaagataa gatttactca ttttcatctg aaagtgttcc agacccttgg
    36541 tatacaggag attttgaaga aacctatcga cgtgttcaag agggctgtca agcttggtta
    36601 gaacgtttag aaaaggagag ttaaggtgga aaatcttacg aatttttacg aaaagtatcg
    36661 tgtctatctg actcgtccac gtttagagct tttggcagta gttaccattg ttttttgtgc
    36721 tgtactcgtc ttttttctaa atattccagg aaaaggtgtc ttaaaactcg ataatggaac
    36781 gattgtttat gatggcagtc ttgtccgtgg taaaatgaat ggccaaggta ccattacctt
    36841 ccaaaatgga gaccaatata caggtggctt caacaatgga gccttcaacg gaaaaggtac
    36901 ctttcaatct aaagaaggct ggacctacga aggtgatttt gtaaatggtc aggctgaagg
    36961 aaaagggaaa ctaacaacag aacaagaagt cgtttatgaa ggaactttta aacaaggcgt
    37021 ttttcaacaa aaataaagcc tccttatcaa aggaggtatt attagaatca caaggtaagc
    37081 gcttacctgt aaatcccttt ctttccaaat ccctcttcca agcaagtttg tgaaataaaa
    37141 aatatttgaa ataaatttca caaacttcaa agataaaact tgataagaaa agaaaatgag
    37201 aaaagtttca caagagttta aaaattcttt gtgaaatgtt tatgaaactg tttacaaagt
    37261 tgaaataatg cgttataata aacttgtgaa aaaattaaca aaggatatcg ttccttgaaa
    37321 gctatggagg aaaatatggc tgataaaaaa actgtgacac cagaggaaaa gaaactcgtt
    37381 gctgaaaaac acgtagatga gttggttcaa aaagctctag ttgcccttga agaaatgcgt
    37441 aaattggatc aagaacaagt tgactacatc gttgccaaag catcagtagc agctttggat
    37501 gcccacggag aattggcttt acatgccttt gaagaaacag gacgtggtgt atttgaagac
    37561 aaagcaacta agaacttgtt tgcttgtgaa cacgtagtaa acaatatgcg ccacactaag
    37621 acagttggcg ttatcgaaga agacgatgta acaggattga ctcttattgc tgaaccagtt
    37681 ggtgttgttt gtggtattac tccaacaaca aacccaacat caacagcaat cttcaaatca
    37741 ttgatttcat tgaagacacg taacccaatc gtctttgcct tccatccatc agcacaagaa
    37801 tcatctgctc atgcagctcg tatcgtccgc gatgcagcta tcgcagctgg tgctcctgaa
    37861 aactgtgtgc aatggattac tcaaccatct atggaagcaa caagtgccct tatgaaccac
    37921 gaaggtgttg cgacaatcct tgcaacaggt ggtaatgcca tggttaaggc ggcttattca
    37981 tgtggtaaac cagctcttgg ggtaggtgcc ggaaacgttc cagcttatgt tgaaaaatca
    38041 gcaaacattc gtcaagcagc acacgatatc gtcatgtcta aatcatttga taacggtatg
    38101 gtctgtgcat ctgaacaagc agttatcatt gataaagaaa tttacgatga atttgtagca
    38161 gagttcaaat cttaccacac ttactttgta aacaaaaaag aaaaagctct tcttgaagag
    38221 ttctgcttcg gcgtcaaagc aaacagcaaa aactgtgctg gtgcaaaatt gaacgctgac
    38281 atcgttggta aaccagcaac ttggattgca gaacaagcag gatttacagt tccagaagga
    38341 acaaacattc ttgctgcaga atgtaaagaa gttggcgaaa atgagccatt gactcgtgaa
    38401 aaattgtcac cagttattgc agttttgaaa tctgaaagcc gtgaagatgg tattactaag
    38461 gctcgtcaaa tggttgaatt taacggtctt ggacactcag cagctatcca cacagctgac
    38521 gaagaattga ctaaagaatt tggtaaagct gttaaagcta ttcgtgttat ctgtaactca
    38581 ccttctactt ttggtggtat cggggacgtt tacaatgcct tcttgccatc attgacactt
    38641 ggatgtggtt cttacggacg caactcagtt ggggataacg ttagtgccat taacctcttg
    38701 aatatcaaaa aagtcggaag acggagaaat aacatgcaat ggatgaaact tccttcaaaa
    38761 acatactttg aacgtgattc aattcaatac cttcaaaaat gtcgtgacgt tgaacgtgtc
    38821 atgatcgtta ctgaccatgc catggtagag cttggtttcc ttgatcgtat catcgaacaa
    38881 ctggaccttc gtcgcaataa ggttgtttac caaatctttg cggatgtaga accggatcca
    38941 gatatcacaa ctgtaaaccg tggtactgag attatgcgtg ccttcaaacc agataccatc
    39001 atcgcactcg gtggtgggtc tccaatggat gctgccaaag taatgtggct cttctacgag
    39061 caaccagaag tggacttccg tgaccttgtc caaaaattca tggatatccg taaacgtgcc
    39121 ttcaagttcc cattgcttgg taagaagact aaattcatcg cgattccaac tacatctggt
    39181 acaggatctg aagtaacacc atttgccgtt atctctgata aagcaaacaa ccgtaaatac
    39241 ccaatcgctg actactcatt gacaccaact gtggcaatcg tagatcctgc tttggtattg
    39301 acagttccag gatttgttgc tgctgatact ggtatggacg tattgactca cgcgacagaa
    39361 gcatacgtat cacaaatggc tagtgactac actgatggtt tagcacttca agccattaaa
    39421 ttggtctttg aaaatctcga aagctcagtt aagaatgcag acttccactc acgtgagaaa
    39481 atgcataacg cttcaacaat cgctggtatg gcctttgcca atgccttcct aggtatttct
    39541 cactcaatgg cccataagat tggtgcgcaa ttccacacaa tccacggtcg tacaaatgct
    39601 atcttgcttc catacgttat ccgttacaac ggtacacgtc cagctaagac agcaacatgg
    39661 cctaagtaca actactaccg tgcagatgaa aaataccaag atatcgcacg catgcttgga
    39721 cttccagctt ctactccaga agaaggggtt gaatcttacg caaaagctgt ctacgaactc
    39781 ggtgaacgta ttgggatcca aatgaatttt agagaccaag gaattgacga aaaagaatgg
    39841 aaagaacatt ctcgtgaatt agccttcctg gcttatgaag accaatgttc accagctaac
    39901 ccacgtcttc caatggtaga ccatatgcaa gaaatcatcg aagatgcata ctatggctac
    39961 aaagaaagac caggacgccg taaataattg tttatcagtc tagaagcaag acaaaaactc
    40021 aatttgaggg aaagatccag taatttttct atgataaaag gcatcctatc aaggtttttg
    40081 aacacctgat aggatgcctt tttatgatat tgaggccttt ttgccctttt tgaaaaacta
    40141 gaatagaaac aaaatatata atagattgaa actggaatag tacacttctg cttctaaaac
    40201 attgttagaa ttcgatttga ctgtcctgat cgatttgtcc tattcctatt tcattttatt
    40261 atataaaaaa tat
//
LOCUS       DAVLBE010000014        40233 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.014, whole genome shotgun sequence.
ACCESSION   DAVLBE010000014 DAVLBE010000000
VERSION     DAVLBE010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 40233)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40233)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40233
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.014"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            <1..752
                     /locus_tag="VXB91_000780"
     CDS             <1..752
                     /locus_tag="VXB91_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0470262.1"
                     /translation="LIPERVSQDIKFDKKIELKDIWYKYGLFDDYVLKGINVTIKKGE
                     TVAIVGESGSGKSTLAKILLGLLEPNIGSIEVDGVEKEEIGQTLYRKIFGAVLQNSTL
                     SYGTLRENLTFGHFVSDEELMTNLNSIGLSNVVKSLPLGLETIIAEEGNNFSGGQQQM
                     ILLARCLLSKPSVVVLDEATSSLDNLSQQITTSYLSEIGTTKILIAHRLDTIKSADKI
                     LVMHNGEIVEIGTHRELLELGGIYKQLYSNN"
     gene            776..2514
                     /locus_tag="VXB91_000781"
                     /pseudo
     CDS             776..2514
                     /locus_tag="VXB91_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699970.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
     gene            2565..3332
                     /locus_tag="VXB91_000782"
     CDS             2565..3332
                     /locus_tag="VXB91_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV0470263.1"
                     /translation="MSQKMNHLDVGEFVLLLPEHLRSEEEHYKSVFEDDLTSRISSQD
                     ERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQSILFWIDAVQ
                     NYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVMLAGAVLGIAT
                     SILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLGFVASVFLQVE
                     IGVAFLVLLLFTGLSLLQLHVQMQKENKMSMLVLKGG"
     gene            3334..3966
                     /locus_tag="VXB91_000783"
     CDS             3334..3966
                     /locus_tag="VXB91_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0470264.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSGSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLIG
                     QKLSRSEQRLRQKQALEQVGLVYLDLDKRIFELSGGESQRVALAKIILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDHLK"
     gene            complement(4895..5308)
                     /gene="ndk"
                     /locus_tag="VXB91_000784"
     CDS             complement(4895..5308)
                     /gene="ndk"
                     /locus_tag="VXB91_000784"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HEV0470265.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYPPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTI
                     RGDFAKAAGENEIIQNVVHGSDSEESAKREIALWF"
     gene            complement(5419..9096)
                     /gene="rpoC"
                     /locus_tag="VXB91_000785"
     CDS             complement(5419..9096)
                     /gene="rpoC"
                     /locus_tag="VXB91_000785"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HEV0470266.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGAIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKAEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPHAVNEEEYLNPPVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            complement(9129..12740)
                     /gene="rpoB"
                     /locus_tag="VXB91_000786"
     CDS             complement(9129..12740)
                     /gene="rpoB"
                     /locus_tag="VXB91_000786"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEV0470267.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TSEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVIAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            13156..13226
                     /locus_tag="VXB91_000787"
     tRNA            13156..13226
                     /locus_tag="VXB91_000787"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:13188..13190,aa:Cys,seq:gca)
     gene            complement(13424..14755)
                     /locus_tag="VXB91_000788"
     CDS             complement(13424..14755)
                     /locus_tag="VXB91_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HEV0470268.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTNTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPVIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFDVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELVSQNKQFILTNDKVKNGRVTKVKVQITEVEIEEETE"
     gene            complement(14984..15808)
                     /gene="endA"
                     /locus_tag="VXB91_000789"
     CDS             complement(14984..15808)
                     /gene="endA"
                     /locus_tag="VXB91_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HEV0470269.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMPSAPNSPKTNLSQKKQ
                     ASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            complement(15847..16035)
                     /locus_tag="VXB91_000790"
     CDS             complement(15847..16035)
                     /locus_tag="VXB91_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEV0470270.1"
                     /translation="MNKKSSYVVKRLLLVIIVLILGTLALGIGLMVGYGILGKGQDPW
                     AILSPAKWQELIHKFTGN"
     gene            complement(16028..17311)
                     /gene="murA"
                     /locus_tag="VXB91_000791"
     CDS             complement(16028..17311)
                     /gene="murA"
                     /locus_tag="VXB91_000791"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEV0470271.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            complement(17335..17565)
                     /locus_tag="VXB91_000792"
     CDS             complement(17335..17565)
                     /locus_tag="VXB91_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HEV0470272.1"
                     /translation="MVQLLFTLSSHMLFIYVSFYLLKDLVRWEKVLKVTDENTRKVRL
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            complement(17623..18660)
                     /locus_tag="VXB91_000793"
     CDS             complement(17623..18660)
                     /locus_tag="VXB91_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HEV0470273.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     INDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFMRINQ
                     FYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            complement(18644..19132)
                     /gene="coaD"
                     /locus_tag="VXB91_000794"
     CDS             complement(18644..19132)
                     /gene="coaD"
                     /locus_tag="VXB91_000794"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HEV0470274.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLYVGIFFNPHKQ
                     GFLPLENRKRGLEKALGHLENVEVVASHDELVVDVAKRLGATCLVRGLRNASDLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGRDIACYVPESILEEIRNEK
                     KD"
     gene            complement(19122..19661)
                     /gene="rsmD"
                     /locus_tag="VXB91_000795"
     CDS             complement(19122..19661)
                     /gene="rsmD"
                     /locus_tag="VXB91_000795"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HEV0470275.1"
                     /translation="MKIVSGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEVGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQMTKEVGKFQLLKMDAER
                     ALEQVSGEFDLVFLDPPYAKEQIVADIEKMAERELFSEDVMVVCETDKAVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            complement(19726..20718)
                     /locus_tag="VXB91_000796"
     CDS             complement(19726..20718)
                     /locus_tag="VXB91_000796"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HEV0470276.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            complement(20830..21513)
                     /locus_tag="VXB91_000797"
     CDS             complement(20830..21513)
                     /locus_tag="VXB91_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HEV0470277.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYFLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            complement(21569..22309)
                     /locus_tag="VXB91_000798"
     CDS             complement(21569..22309)
                     /locus_tag="VXB91_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HEV0470278.1"
                     /translation="MTIITSKANSVVKNAKKLRQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFALENYRDQLATFSQTVWVSEDILLDLADSQTPQGIVAVVQKEEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSQALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVAAGILIFHLS"
     gene            22343..22621
                     /locus_tag="VXB91_000799"
     CDS             22343..22621
                     /locus_tag="VXB91_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HEV0470279.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYSDFKIAN"
     gene            22699..23625
                     /gene="yidC"
                     /locus_tag="VXB91_000800"
     CDS             22699..23625
                     /gene="yidC"
                     /locus_tag="VXB91_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEV0470280.1"
                     /translation="MKSIKRFALSAMGAAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVREELAKNPPKASAFSK
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(23700..24494)
                     /gene="pflA"
                     /locus_tag="VXB91_000801"
     CDS             complement(23700..24494)
                     /gene="pflA"
                     /locus_tag="VXB91_000801"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HEV0470281.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTRQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKKLMDTESYQDYMKRVHG"
     gene            complement(24620..25870)
                     /locus_tag="VXB91_000802"
     CDS             complement(24620..25870)
                     /locus_tag="VXB91_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HEV0470282.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYARELGATINLDAFEDIEHLERVAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGIHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     IWLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTSAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLMRPAMYGAYHHISNVTHPDGPAEAVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            complement(25937..26764)
                     /gene="purR"
                     /locus_tag="VXB91_000803"
     CDS             complement(25937..26764)
                     /gene="purR"
                     /locus_tag="VXB91_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HEV0470283.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLREFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK"
     gene            complement(27031..27972)
                     /locus_tag="VXB91_000804"
     CDS             complement(27031..27972)
                     /locus_tag="VXB91_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HEV0470284.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMTNKIFAMDNRSFYKPDLD"
     gene            complement(27962..29218)
                     /locus_tag="VXB91_000805"
     CDS             complement(27962..29218)
                     /locus_tag="VXB91_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HEV0470285.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVVVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYETGDKDEIERCRKSLLASVKRFAKDIKSKYI
                     APPRTTNFGVLFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLHFQENEEEYED"
     gene            complement(29220..29882)
                     /locus_tag="VXB91_000806"
     CDS             complement(29220..29882)
                     /locus_tag="VXB91_000806"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HEV0470286.1"
                     /translation="MSEYKLSENNWTRVAVFAGGDRGHYRTDFDAFVGVDRGSLWVLE
                     EDLLLALAVGDFDSVTEEERQVIQKRAQHFVQARPEKDDTDLELALLTIFEKNPQAQV
                     TIFGALGGRIDHMLANVFLPSNPKLAPYMHQIEIEDGQNLITYCPEGTSQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            complement(29845..30501)
                     /locus_tag="VXB91_000807"
     CDS             complement(29845..30501)
                     /locus_tag="VXB91_000807"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEV0470287.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDSHFVP
                     QISFGAGVVESLRPHSKMVFDCHLMVSNPEHHLEDFARAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTSVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALREEKGLNFEIEVDGGIDDQTIAQAKEAGATVFVAGSYVFKGDVNERVQTLRKQLD
                     "
     gene            complement(30512..31390)
                     /gene="rsgA"
                     /locus_tag="VXB91_000808"
     CDS             complement(30512..31390)
                     /gene="rsgA"
                     /locus_tag="VXB91_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HEV0470288.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDRGELDFYQQTYGDIGYDFVTSKEELLSLLTGKVTVFMGQTGV
                     GKSTLLNKIAPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVS
                     RAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGVIATFRFDNYLQFLSEI
                     ENRRETYKKVSKKIPK"
     gene            complement(31392..32264)
                     /gene="rsmA"
                     /locus_tag="VXB91_000809"
     CDS             complement(31392..32264)
                     /gene="rsmA"
                     /locus_tag="VXB91_000809"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HEV0470289.1"
                     /translation="MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAQVMAFEIDHRLMPILADTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPNLPIKVVANLPYYITTPILMHLIESGIPFCEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPEPAVAVED
                     ENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLA
                     EFAGLADALKGQGL"
     gene            complement(32515..32808)
                     /locus_tag="VXB91_000810"
     CDS             complement(32515..32808)
                     /locus_tag="VXB91_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0470290.1"
                     /translation="MCEKIRIRRVSDYPSARGGLEDILIMENMTNHLLLVQIRVHGYL
                     LDFASIEGQRQKHYRLKNLPQTVELTVDDVEEDVDLTLPENRSYQEADFFDTQ"
     gene            complement(32801..33442)
                     /locus_tag="VXB91_000811"
     CDS             complement(32801..33442)
                     /locus_tag="VXB91_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0470291.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVGALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRIIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            complement(33444..35474)
                     /locus_tag="VXB91_000812"
     CDS             complement(33444..35474)
                     /locus_tag="VXB91_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV0470292.1"
                     /translation="MKRLFILISMVLVSLYMVITSVDHREEILFGNYPSVDVTGMMIN
                     QPVASREEVTEALSHLAVEHNSLIARRIVEPNEAGETLFTYATYGEGELPEGLTISSK
                     ESAETSDLLGSYLIVSGSLDGVSLQTTLKELGYQGFVSNGEDPFSIVLLLAATPMVLL
                     SLAIFLLTFMSLTLIYRIKSLRQAGIRLIAGESLFGVALRPVLEDVRQLICSVLVSSL
                     LGLGILWYQGALFMATVQLVIIALLLYGLTLAGISTLLSVVYLLGLQENSLVDLLKGK
                     LPLKRMMTLMMVGQLLAVLVVGSSATALLPHYREMQEMERASNKWSQSSDRYRLSFGW
                     SSAFADEEGTRKDNREWQTFTEERLANTDSFYIMSNVDNFSDGAEVDLDGNRLSDYTP
                     LGNVIYVSPRYLIEEKITVSSEFMDKMQNLSEGEFGLILPESLREQSAYYQGLFTDYL
                     QNFSSESVEVTSQKHYLPQVRLAFTETGQERFLYNDGYKTTRQYLKDPIIVVLTPQAT
                     GTRPVAGMLWGTTANSALKLDRYGDSITALKEQGLYHKVSYLVKSQLFFAKVLNDKRV
                     EFYSLLIGTILTLSTAILLFDSMNLLYFEQFRRELMIKRLAGMTIYELHGKYLLAQGG
                     VLLLGLVLSSILTRDGLISALVVALFTLNALLILVRQDKKEEAGSMAVLKGK"
     gene            complement(35551..35847)
                     /locus_tag="VXB91_000813"
     CDS             complement(35551..35847)
                     /locus_tag="VXB91_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEV0470293.1"
                     /translation="MKQTVKKLALVASIAATLGGGVSVASAAVQYPEGGVWTYGSGNG
                     GAYSNYYHPSKYHSSTVVSRKTGSSDKGYAGAGGTSRAWIRTSWGEKVAFYYNV"
     gene            complement(36167..37066)
                     /locus_tag="VXB91_000814"
     CDS             complement(36167..37066)
                     /locus_tag="VXB91_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0470294.1"
                     /translation="MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPS
                     LPKLAYIARRLGVPVYSLMPDFSALPSAYLELKYQILREPIYGKEEEYDKKEACLEEI
                     YKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMSQIIEKEVYSTNDMLL
                     IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTKLENFFIIRDTLISGMCCLEKVG
                     VTDCFNDYLSCLQEIMDKTQDYQKKPLVFMFLWKQALRVERDFSLAESFYQSSKTFAK
                     LIGDGFLVKKLTEEWQEDVKKYL"
     gene            complement(37138..37698)
                     /gene="rnmV"
                     /locus_tag="VXB91_000815"
     CDS             complement(37138..37698)
                     /gene="rnmV"
                     /locus_tag="VXB91_000815"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HEV0470295.1"
                     /translation="MKEKISQVIVVEGRYDTVNLKRYFDVETYETRGSAINDQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMTAIPTVQHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLAGADSRKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            complement(37698..38471)
                     /locus_tag="VXB91_000816"
     CDS             complement(37698..38471)
                     /locus_tag="VXB91_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HEV0470296.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALAAEMGVIQMNIVGFDKPTIE
                     RALELVDEYEQLYATIGWHPTEAGTYTEEVEAYLLDKLKHSKVVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIQLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELPLDKMLVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAVATTANAERIFGLDSK"
     gene            complement(38776..39669)
                     /locus_tag="VXB91_000817"
     CDS             complement(38776..39669)
                     /locus_tag="VXB91_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HEV0470297.1"
                     /translation="MVAQDPKAQDSTKPTAEKSTVKAPAQRVDVKDITHLTDEEKVKV
                     AILQANGSALDGATINVAGDGTATITFPDGSVVTILGKDTVQQSAKGESVTQEATLEY
                     KLETIPGGDKGGNTGSSDANANEGGGSQAGGSAHTGSQNSAQSQASKQLATEKESAKN
                     AIEKAAKDKQDEIKGAPLSDKEKAELLARVEAEKQAALKEIENAKTMEDVKEAETIGV
                     QAIAMVTVPKRPVAPNAAPKTTSAPQATAGTMQDVTYQSPAGKQLPNTGSASSAALAS
                     LGLVVATSGFALLGRKTRRRK"
     gene            complement(39953..40087)
                     /gene="rpmH"
                     /locus_tag="VXB91_000818"
     CDS             complement(39953..40087)
                     /gene="rpmH"
                     /locus_tag="VXB91_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HEV0470298.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
BASE COUNT        11635 a         8989 c         7704 g        11905 t
ORIGIN      
        1 aattaattcc agaaagagtc agtcaagata taaaatttga taaaaaaata gaattaaaag
       61 atatttggta taaatatgga ttatttgatg attatgtttt gaaaggaata aatgttacta
      121 ttaaaaaagg agaaactgtt gctattgttg gagaatcagg ttcaggtaag agtacattag
      181 ctaaaatttt attaggttta ttagaaccta atattggttc aatagaagtt gatggagtag
      241 aaaaagaaga aattggtcaa acattgtata gaaagatttt tggagcagtg ttacaaaatt
      301 caaccctaag ttatggtacc ttaagagaga atttgacatt tggacacttt gtttcagatg
      361 aagaattaat gacaaatcta aattcaattg gtcttagcaa tgtagttaaa tctttacctc
      421 ttggattaga gacaatcatc gctgaagaag gtaataactt ttctggaggg cagcagcaaa
      481 tgatactttt agctcgttgt cttttgtcga aaccttcggt agttgttttg gacgaagcaa
      541 caagtagttt agataattta tctcaacaaa ttacaacttc ttacttaagt gaaatcggta
      601 ccactaagat tttaattgcc catcgactag atactatcaa gtctgcagat aagatcttag
      661 taatgcataa tggtgaaatt gtagagattg ggacccatag agaacttctt gaactaggag
      721 gcatttataa gcaattgtat tcaaataatt agtttttgat taaaagggta aatttatgaa
      781 gattatgaaa aaaaaatatt ggactttagc gatattattc ttttgtttgt tcaataattc
      841 tgttactgct caagaaatac ctaaaaatct tgatggcaat ataactcaca ctcagactag
      901 cgaaagtttt tctgaatctg atgaaaaaca ggttgactat tctaataaaa atcaagaaga
      961 agtagaccaa aataaatttc gtattcaaat cgataagaca gaattatttg taacaacaga
     1021 taaacattta gaaaaaaact gttgtaaatt ggaacttgaa ccacaaataa ataacgatat
     1081 tgttaactct gaaagtaata atttactagg cgaagataat ttagataata aaattaagga
     1141 aaatgtttct catctagata atagaggagg aaatatagag catgacaaag ataacttaga
     1201 atcgtcgatt gtaagaaaat atgaatggga tatagataaa gttactggtg gaggcgaaag
     1261 ttataaatta tattctaaaa gtaattctaa agtttcaatt gctattttag attcaggagt
     1321 cgatttacaa aatactggat tactgaaaaa tctttcaaat cactcaaaaa actatgtccc
     1381 caataaagga tatttaggaa aagaggaggg agaggaagga ataatatcag atattcaaga
     1441 tagattaggt catggtacgg ctgttgtagc tcaaattgta ggggatgaca atattaatgg
     1501 agtaaatcct cacgttaata ttaacgtcta tagaatattt ggtaagtcgt cagctagtcc
     1561 agattggatt gtaaaagcaa tttttgatgc tgtagatgat ggcaatgata ttatcaatct
     1621 tagtactgga caatatttaa tgattgatgg agaatatgag gacggaacaa atgattttga
     1681 aacatttttg aagtataaaa aggctattga ttacgcgaat caaaaaggag taattatagt
     1741 agctgcatta gggaatgact ccctaaatgt atcaaatcag tcagatttat tgaaacttat
     1801 tagttcacgc aaaaaagtaa gaaaaccagg attagtagtt gatgttccaa gttatttctc
     1861 atctacaatt tcggtcggag gcatagatcg cttaggtaat ttatcagatt ttagcaataa
     1921 aggggattct gatgcaatat atgcgcctgc aggctcaaca ttatctcttt cagaattagg
     1981 acttaataac tttattaatg cagaaaaata taaagaagat tggatttttt cggcaacact
     2041 aggaggatat acgtatcttt atggaaactc atttgctgct cctaaagttt ctggtgcgat
     2101 tgcaatgatt attgataaat acaaattaaa agatcagccc tataattata tgtttgtaaa
     2161 aaaattctgg aagaaacatt accagtaaaa aatggtataa aagtgttaaa tataccaaac
     2221 gtattgagat atgatttgaa tatgttacaa ttagaatata aaaatgaaca aagttgggat
     2281 agtttcatag ataatgttaa tttaattgag ttggaagaga gaattcaaac tactattgga
     2341 attaaacaaa taaacacaca caatattatt actattgccc gagaagggta ctctcaaaat
     2401 tatttaccta acacttcaga aaatacatat aattcattac aagtcagttt agttggagta
     2461 ttactacttt ttataagtat ggtaaatatt ttatgggcta aaaaaagtaa atgaaaataa
     2521 aatttggagc cctctgaaaa agtaagtcct acagttcaac taaaatgagt caaaagatga
     2581 atcaccttga tgtaggggag tttgtcttat tgctgcctga acacctccgt tcagaggaag
     2641 aacattataa atctgttttt gaagacgact taaccagtcg catatctagt caagatgaac
     2701 gacagcaaat gactgctacg gtaggttatt tagaatcagg tcaggatcgt tttgtgtata
     2761 atacgacccc tatttcttac cagcagtttt tgaaagatcc aatcatcatt gttataacac
     2821 cccaatcaac tggtccacag tccattttgt tttggataga cgcagtacag aactacgttc
     2881 tctttaatca attgtctgat gcccaggagc ttatccagag acaaggcatt gaaaattggg
     2941 tctcagaaat gcaaacaggt taccacaact acatcacatt attggataat atccagaggg
     3001 aacgttgggt aatgctagca ggagctgtgc ttgggattgc aacttcaatc ttgttgttta
     3061 acactatgaa taggctctac tttgaagaat ttagacgtgc catttttatc aaacgcattg
     3121 caggtctcag gttcttagaa atccatcgca cttatctctt tgctcaactg ggtgtgtttt
     3181 tactgggatt tgttgcgagt gtatttcttc aggtagagat aggagttgct ttcttagtct
     3241 tgttactctt tactggtcta tctcttttac agttacatgt ccaaatgcag aaagaaaaca
     3301 agatgtccat gcttgttttg aagggaggtt aatatgattg aacttaaaca ggtgagtaaa
     3361 tcttttggag aacgagagtt attttcgaat ctttcaatga catttgaggc tggaaaagtc
     3421 tatgccttaa ttggttcaag tggtagcgga aaaacaacct tgatgaacat gattgggaaa
     3481 ttagaacctt atgatgggac gattttttac cgaggtaaag acttggccaa ttataaatca
     3541 agtgattttt tccgtcacga attgggctac ctcttccaga actttggctt aattgaaaac
     3601 caaagtattg aagaaaacct taagctaggt ctcattggtc aaaagttgag tcggtcggaa
     3661 cagcggttga ggcagaagca ggctttagaa caggtcggcc tggtttatct tgacctagat
     3721 aagcgcatct ttgagttatc gggcggagaa tcgcaacggg ttgccttggc aaaaattatc
     3781 ttaaagaatc caccctttat tctggcagat gagccaacag cttcaataga cccagcaacc
     3841 tctcagttga ttatggagat tttgctatct cttcgagatg ataataggct aatcattatc
     3901 gcaacacata atccggcaat ttgggagatg gctgatgaag tgttcacgat ggatcatctg
     3961 aaataaaaat ccttgttttt aattgcacga tgagttactg aaatattatc atgaatcaag
     4021 aattggagtt aatttagaat tgtactttat taatattgag gtaacttttt cttgataaag
     4081 gaagaaataa tggagaggaa gttagaatga aaaaattcga caattatatt attgagaagc
     4141 cttgcgattc taattcagat aaactgcaaa aaatcttaat aattgaaagt ttggtagatg
     4201 atattttgca attttctctc agaatcaata atagtgtagg agagattttc ctcctacaac
     4261 cgttttaaaa gaaaactatc tttattccat gttattttga ggaagatatt gtgaaagtca
     4321 aagatgatga taaagttgag tggaatttgt tagaatttca aaaatttaga gcatttttgg
     4381 cttagtaatc tgtgttgaag gctcaaaacc tatggtaaaa aagtagcttt gaaaacgtat
     4441 tgcctccaaa gatttagtta aataatgatt taacacaaaa agaaattatt gaagttctgg
     4501 aaagatgttg tttcagtatt gagaaaaggt gggaaaaact tgcgattttc acagagaaag
     4561 gaagaaaaag tatagaaata tagtcaattg aaacaagaac aggataaaag aaccttttgt
     4621 gccatatttt tctcctttcg ctttacaatt ggattgaaca cctttattgt atcgcgtttg
     4681 gagttttttt ggtataacct tcgacgcaca cccgcatagc gggtgttttt tttgtctcgc
     4741 acctaacgga gcgagacaaa ctaatagtca cttaatcaaa aaacgcacca tatcaaaaac
     4801 taaaaagttt gatatcatgc gtcatgtctt aaactaattg actatacttt ctattcaaat
     4861 gagcttttaa ccaattgatt gagccaatcc actcttaaaa ccaaagagca atttctcgct
     4921 tagctgactc ttctgaatct gaaccatgta caacattttg gataatctca ttttctccag
     4981 cagcttttgc aaaatcacct cgaatagtgc ctggtaaagc ttcttctgga cgagttgcac
     5041 ccatcatggt ccgccaagtt tcgattactt tgggaccaga aatgacaccc acaagaactg
     5101 gacctgaagt catgaattca cgaatcggtg ggtaaaaact ctgaccaacc aagtcctgat
     5161 agtgctggtc aatcaactct tctgaaacct gtgaacgaaa ctccaatttt tcgattgtaa
     5221 atccacgttg ttcgatgcgc tttaacactt cacccactag ccctcttttt acaccatctg
     5281 gtttgatgat aaagaatgtt tgttccatac ccgtctcctt tgtcagcttc tttcttttat
     5341 tttaccacat ttcgtggaaa aatggagaaa gttttcagaa gagagaatga gagaaccctc
     5401 gggttctctc attctctctt attctactgt ttcttccaca gtttcaacgg cagtatccac
     5461 aactacttct gttgtttctt catttccttc ttcctctact ggaggattaa ggtattcttc
     5521 ttcgttgaca gcatgtggtt caaggttacg gtaacgggcc ataccagtac cagctgggat
     5581 gatcttaccg atgataacat tttctttaag tccaaggaga tggtctttct taccacggat
     5641 agctgcgtca gtaaggacac gagttgtttc ctggaaggaa gccgctgaca agaaactgtt
     5701 tgtttcaagt gaggctttgg taattcccat aaggactggg cgacctgtcg ctggaactcc
     5761 acctgcgata aggacatctt tgttggcatc tgtaaagtca ttgatatcca tgagggtacc
     5821 catgagaaga tctgtatcac ctggatccat gacacggact ttacggatca tttgacgaac
     5881 cattacctcg atgtgtttgt caccgatttc taccccttgg ctacggtaaa ctttttgtac
     5941 ttcaccgaga aggtacgttt caactgacaa gacatcacga actgcaagga gacgttttgg
     6001 ttggatagaa ccttctgtca gagcagcacc acgcgctact tggcccccaa cttcgacacg
     6061 catacgagct gtaaatggaa cgacatattc accttcgcca gtttcaccct taacaaagac
     6121 tttcttggta cgagttgatg catcttcttc gatagcagta acttgtcctt taacctctgt
     6181 aataaccgct tcccctttag gattgcgggc ttcaaagatt tcttggacac gaggaagacc
     6241 ctgagtgata tcggtatttg aggcaacccc acctgtgtgg aaggtacgca ttgtaagctg
     6301 tgtaccaggt tccccgatag attgggcagc gattgtacca actgcttcac caacttcaac
     6361 cgcatcacca gtcgccaagt tgataccgta acagtgacgg cagacaccgt gacgagtgtt
     6421 acatgtaaat acagaacgga tagtcacttc ttccacacca gcattgacaa tttcacgcgc
     6481 cttgtcttct gtaatcaatt catttggacc aataatcact gcaccagttt ctggatgttt
     6541 aacagttttc ttagtgtaac gaccgttgag acgctcttcg agagactcga tcatctcttt
     6601 tccttctgcg atagaacgga tcaagagacc acggtcagtt ccacagtcgt cctcacggat
     6661 gataacgtct tgggcaacgt cgaccaaacg acgagtcaag taacctgagt cggctgtctt
     6721 aagggccgta tcggtcatac ctttacgagc accgtgagtt gagaagaaca tttccaatac
     6781 cgacaaacct tcgcggaagt ttgaaaggat tggcaattcc atgatacgtc cattcggagc
     6841 agccatcaga ccacgcatac cggcaagctg tgagaagttt gagatgttac cacgggctcc
     6901 agagtccatc atcataacga ttgggttctt aggatcttga ttagcaatca agcgtttctc
     6961 aagtttttca cgggcagcac gccattcagc tgtaacagca ttgtaacgct cgtcgtctgt
     7021 gatcatacca cgacggaatt gtttggtgat ttgttcgaca cgtttgtgtg attcttcaat
     7081 gatttcagcc ttgtcatcaa cgactgggat atcggcaata cccactgtca atcctgcaag
     7141 agttgagtgg tggtaaccga ggttcttcat gcggtcaagt agggcagaag tttctgtcgt
     7201 acggaaacgt ttgaagattt cagcgatgat atttccgagg tttttcttct tgaatggagg
     7261 gttgagctca agattgctga tagcttcctt gatagctcca ccaagtggca agaagtattt
     7321 agctggaaca ccttctgtca agttggcatt gtttggttct tgcaagtatg gtagcccctc
     7381 tggcatgata tcgttgaaga gaattttacc aactgttgta agcaagacct tatgtctttg
     7441 ctcttctgtc caaggcttgt tgaggctgtc tgttgcgata ccaacacgtg agtggaggtg
     7501 aacataacca ttgcggtaag ccataaccgc ttcgtcacgg tctttgaaga ccattccttc
     7561 accttcgcga ccagcttctt ccatggtcaa gtagtagtta cccaaaacca tgtcctgaga
     7621 tggagtaact accggtttcc catctttcgg gttcaagatg tgctcagcag ctagcatgag
     7681 gatacgagct tctgcttgtg cttcttctga aagtggtacg tggatggcca tttggtcccc
     7741 gtcaaagtca gcattgtagg cttcacagac aagtgggtgc aagcgaagag ccttaccatc
     7801 aatcaagact ggctcgaagg cttggatacc caaacggtga agggtcggtg cgcggttcaa
     7861 aagcactggg tgttctttaa tcacttcttc aaggatatcc cagatacgct catctccgcg
     7921 ttccaccaag cgtttagctg ctttgacgtt ttgcacgata tcacgggcaa cgatttcacg
     7981 catgacaaat ggtttaaaga gttcaatcgc catttcacgt ggcacaccac attggtacat
     8041 cttaagagtt ggaccaacgg cgataacgga acgtcctgag aagtcaacac gtttaccgag
     8101 caagttttga cggaagcgtc cttgtttacc tttaagcatg tggctcaatg atttcaatgg
     8161 acggctacct ggtcctgtga ttggacgacc acgacgacca ttgtcaatca aagcgtcaac
     8221 tgcttcttga agcatacgct tctcattttg aacgatgata cctggtgcat ttaactcaag
     8281 caaacgagcc aaacggttgt tacggttgat aacacggcgg taaaggtcat tcaagtcaga
     8341 tgaggcaaaa cggccaccat ccaactgcaa cattggacga agatctggtg ggataaccgg
     8401 aaggatgtta agaatcatcc attcaggttt gtttccagac ttgtaaaagg catccaaaac
     8461 atccaaacga cggatggctt tgacacgttt ttgtccagta gcagttttca attcttcttt
     8521 gagttcagca atttcttttt caagatctac ttgcttcaaa aggtcttgga tggcttccgc
     8581 acccatctta gcaacaaatg aaccataacc atattcgcgc aagcgctctc ggtattcgcg
     8641 ctctgtcatg atagacttgt gctcaagtgg tgtatcctta ggatcaatca ccacataagc
     8701 cgcaaagtag ataacttcct cgagggcacg agggctcata tcaagggtca agcccatacg
     8761 gcttggaatc cccttgaagt accagatgtg agatacagga gctttcaatt cgatatgtcc
     8821 catacgctca cgacgaactt tcgtacgcgt tacttcaacc ccacagcggt cacaaacaat
     8881 tcctctgtaa cgaatgcgtt tgtacttacc acaagcacat tcccagtctt ttgtaggacc
     8941 aaagatcact tcatcaaaga gtccttcacg ttctggtttc aaggtacgat aattgattgt
     9001 ttcaggtttt ttgacttctc cataagacca tgaacggact ttacttggag aagctagggt
     9061 gatttgcata cttttaaaac gatttacatc aaccactatt tcttcccttt ctattctaag
     9121 tgaactgctt attcttgttc agcagcttct tctgttgctt ccgcttttgt tgctttctca
     9181 gcttcttcag cttcaaaggc tgctttagcc tcttgggctg ctttttcgcg ggctttttca
     9241 aggtcatcta cgtggatgac atcttcgtcc attccttcat ccaagtcgcg aagttccact
     9301 tcttggtcat cttcgtctag gacacgcatg tcaagaccaa gagattgcaa ttctttgaca
     9361 agaactcgga aggattctgg aacacctggt tttggaattg gtttgccttt tgtaatagct
     9421 tcataggctt tcaaacgtcc gttgatatcg tccgacttgt aagtcaagat ttcttgaagg
     9481 acatttgacg caccgtaggc ttcaagagcc caaacctcca tctcaccgaa acgttgtcca
     9541 ccaaactgag ccttacctcc gagtggttgt tgggtaacag ttgagtatgg tccgactgaa
     9601 cgcgcgtgca atttatcatc aaccatgtgg tggagtttga tcatgtacat gactccgaca
     9661 gaaacacggt tatcaaacgg ttcaccagta cgtccatcgt aaaggatcgt tttggcatcg
     9721 ctatccatac ctgcttcttt aacagttgac caaagatctt cagaacttgc tccatcaaag
     9781 actggtgtag cgatgtgaat accaagagta cgagctgcca taccaaggtg aagctccata
     9841 acctgaccga tattcatacg tgatggtacc ccaagtgggt tcaacatgat gtcgactgga
     9901 gttccgtctg gaaggtaagg catgtcttct acaggaacga tacgagagac aacccctttg
     9961 tttccgtgac gtccggccat tttatctccg accttaatct tacgtttttg agcgatgtaa
    10021 acacgaacca acatgttaac acctgattgc aactcatctc catttacacg tgtaaagatc
    10081 ttaacatcac gaacgacacc atcggcaccg tgtggtacac gaagagaagt atcacgcact
    10141 tcacgagact tgtctccaaa gatagcgtgc aagagacgtt cttcagctga aagatctttc
    10201 tcacccttag gtgttacttt acctacaaga atatcacctt ctttaacctc agcaccaata
    10261 cggataatcc ccatttcgtc aaggtctttg agggcatctt caccaacgtt tggaatttcg
    10321 cgagtgattt cttcaggccc aagctttgta tcgcgcgttt ctgattcgta ttcttcaagg
    10381 tgaacagatg tgtagacatc gtccttcacc aagcgttcgc tcatgataac ggcatcctcg
    10441 aagttgtaac cttcccaagt catgtaggca acgattgggt tttgtccaag cgccatttct
    10501 ccattttcca tagaaggtcc gtcagcgatg aaatcgcctt tttcaacgac atcaccaact
    10561 tttacgagag tgcgttggtt gtaagcagta cctgagtttg aacgacggaa tttttggatg
    10621 tggtaaacat ccaatgaacc atcttcacga cgaacttcta ccttgtcagc atctgcgtaa
    10681 gtaactttac catcatactg agcaatcaca gccgcaccag aatcgtgggc tgcttggtat
    10741 tccataccag taccaacgta aggtgcctga ggattaatca atggcacagc ctgacgttgc
    10801 atattggctc ccatgagggc acggttggag tcatcgtttt ccaagaaagg aatacatgct
    10861 gtcgcaacgg caactacctg ttttggtgaa acgtccatgt agtcaacaat attagctgga
    10921 tactcttggt tgaccccttg gtgacgtccc atgacaatct tctcagcaaa ggttccatct
    10981 tcattcagac gagagttagc ctgagctaca gtatattcat cttcttcatc agctgtcaac
    11041 caaacaattt cgttcgtgac aacacctgtt tcacggtcaa ccttacggta tggtgtttga
    11101 acaaaaccat atttgttcaa gtgtccgtaa gatgacaagt tattgatcaa accgatgtta
    11161 ggtccttcag gtgtctcgat tggacacata cgaccatagt gagtgtagtg cacgtcacgc
    11221 acttcatatc cagcacggtc acgagtcaaa ccaccaggtc ctaaggctga caaacggcgt
    11281 ttgtgagaca actcagaaag cgggttgtgt tggtccatga actgtgacaa ctgtgatgaa
    11341 ccaaagaatt ctttaactgc agctgttaca ggacgaatat tgataatttg ttgtggtgtc
    11401 aagacttcat tgtcctgaac agacatacgt tcacggacat tacgttccat acgagaaagt
    11461 cccaaacgta cttggttggc aagcaattca ccaaccgcac ggatacgacg atttccaagg
    11521 tggtcgatat catctacacg gccaagtcct tcagccaagt tgaggaagta gctcatctca
    11581 gcaaggatat ctgcaggagt caccgtacga accttgtcat ctgggttagc attaccaatg
    11641 atcgttacga cgcgatctgg atcagttgga gcaataacct tgaatttttg aagaacaaca
    11701 ggctcagtca caacggctgc atcgtttggg atgtagacaa tcttgttcaa gtcgccatcc
    11761 aaatggcttt caatgctttc aatcacgcta cgagtcataa tcgtaccagc ttctaccaag
    11821 atttctccag tttcagggtc taccaatggc tctgcaatgg tttggttgag taaacgtgtt
    11881 ttaacattga gttttttatt gattttgtaa cgaccaactg ctgccaagtc ataacgacgt
    11941 gggtcaaaga agcgagctac aagcaagcta cgtgagcttt cagccgtctt aggctcacct
    12001 ggacgaaggc gttcgtaaat ttctttcaag gcttcgtctg tacgagagtc cattggattc
    12061 ttgtggatat ctttttcaac agtgttgcga accaattcgc tgtcaccaaa gatatcaaag
    12121 atttcatcat cacctgagaa accaagagca cgaaccaagg ttgtaaatgg aatcttacga
    12181 gtacggtcga tacgagtgta ggtgatatct tttgagtcgc tttcaagttc caaccaagct
    12241 ccacggttag ggataacagt tgaaccatag cccaccttac catttttgtc tactttgtcg
    12301 ttaaagtaaa cacctggtga gcggaccaac tgagaaacga taatacgttc accaccattg
    12361 atgatgaaag tacccatttc tgtcatgatt gggaaatcac caaagaaaac ttcttgggtc
    12421 ttgatttcgc ttgtttcttt attgatcaaa cggaaggtta caaaaattgg tgctgagtag
    12481 ctagcatcgt ggatacgagc ttcttctagc gtatattttg gttccttgat ttcatatcca
    12541 acaaattcca actccattgt gtctgtgaag tttgaaattg gcaatacatc ttcaaacact
    12601 tccttaagac cgtggtctag gaaagctttg aatgagtcag tttgaatttc aatcaaattt
    12661 ggtaagtcaa gaacttcttt gattcttgaa aaactacgac gggtacgatg tttcccgtat
    12721 tgaacgtcat gtcctgccaa gatgattctc ctttgtaaat aagttccaag ccttgtcaat
    12781 caggcttttc taatcgtcat atggttgtaa accccttatc accgtgtcct cttgacgaat
    12841 tttcagaatc tttaagcctc tgttacaaat gctcaaaatc ttgaaaaaaa gcacaaaaag
    12901 agcagctaaa tctgactttt tcagaagatt taactgctgt gagccttgtc tggacaatat
    12961 ttcagacaaa acctacgaca aatgattacc catattatac cctatttagc tagatttttc
    13021 aaggggtttt agtaggtttt tggtaaattt tttcccatag aaaacttggc atcacattcg
    13081 aatcacgcta tggtacaaaa aactgaaaaa actattgact gaaaatcatt ttcaaggtat
    13141 aataataaac gttaaggcgg tatagccaag tggtaaggca cggctctgca aaagcttgat
    13201 cgtcggttca aatccgtcta ccgccttcta taacttgatt tatcaggttt caaatgaaca
    13261 gaaagcccaa tttgaagggc tttttttatt ttccctcgaa taaatacgta taactttaaa
    13321 aacttttgga gcgagtttgt ggcagagttc tttccatggc ataattccct tttgaaatca
    13381 attgaaaaaa gcttcgtcac gcctggtgac aaaagcctct agtttattct gtttcttctt
    13441 ctatttcgac ttctgtgatt tggactttta ccttggtaac acgtccattc ttcactttat
    13501 cattggttaa gataaactgt ttgttttggc taaccaattc atagctgagt ttctcagtcg
    13561 ttggaatagt tcccactcct gtcaaataat aaccagcgat ggtatcaacg tcatcacttt
    13621 ccagttcaac atcaaagtaa ttattgaaat cattgagggt catagttcct tgaacaatgt
    13681 aggtatcctc gccaatctga tgaacatcta ttgctgcttt gtccgtttca tcatcaattt
    13741 caccaacaat ttcctctaag aggtcttcca aagtcaccaa accagccata ccaccgtatt
    13801 catccagcaa gattgccatt tgtctttggg tatttcgcag ttcttttagc aagtcatcca
    13861 caaaaatagt ttcaggtaca aaaagtggat cttgcaaaat tctcttccaa acaatattgt
    13921 caaaaccgtc cacaaagcct gccttaagga gactcttggt gtgaatgatt ccaattacat
    13981 tgtccttatc cccatcataa accgggatac gagaataatt ttgttttaaa atactttgga
    14041 taatggcttg actatcatcc tgaatatcca ccataaaggc atccgttcga ggaaccataa
    14101 cctctcgtgc catcagttca tcgagcgaaa agacaccttg tagcatctca atctcatcag
    14161 catccaatgt ttcttcacta tttgtcagca tataggcaat ttcatcacgg gtcatctttt
    14221 catccgcatc atcgaatgac ataggagtca aatggctcaa gaaattggtc gaagcagcta
    14281 aaagccaaac aaaaggactg actagttttc cgatcccaat gataaccggc gctgtacgaa
    14341 ttgccaaggc atcctttaga ttaagagcga ttctcttagg atataattcc ccaaaaacga
    14401 tggaaatata ggtcaaaaat gccaaggata gaaaagttgc cacggcttgt gctgtttcgc
    14461 cattcccaag ccaagaggca atcacacgtc ctagagtatt agttaaactc gcccctgata
    14521 agattgtaat cagggtgatt cctacctgaa tggttgataa aaagtggtta ggattttcta
    14581 gtaccttcag caggcggatg tagcgtctgt ctccttcttc cgccttttgt tcaactcggg
    14641 cacgattaag agaaaccatg gccatttctg tggctgagaa aaaggcattt aataccgtca
    14701 agataaacaa taaaacaaat tgtagcaaca aattctgact acttgggtct tccatagttc
    14761 ttctcctaaa atagtatctt atcctttatt atatcacaaa atttaatcca atacatatta
    14821 ttttttctta ccgtaacttc tcaaagtaac ttccatctct ctcccaaaac tggaagttag
    14881 ttttagaagt tgctattttt tcttagtacc tgttctagcc ctgcttaaac tagtaaaaag
    14941 aactcctaca tccataagtg acataggagt ttaggcttat cttttactga gttacagtta
    15001 cttctccagt tcggtaatcc agttgaagtc ccttttgaac attgggaact agaacattga
    15061 attccaattc tccatccgaa gacttggctt caatctgtga agctgaggga actaaatcct
    15121 cgtttgaagc gtagtaaagg gttacacggt aacggacacg cttgttttgg tccaaggctt
    15181 tacgcacctt gctttcatag tagttttgac cagtcgaata ctcggcttgt gcctgatttg
    15241 cccaggctgt ctgaacagca atgtttttag gattgcttgt tgaggcatca aaaccatcca
    15301 aaccaccgat taaggcatag cctaacaaat gacctctatc gactgcatgg gtataagagc
    15361 cctttagatt cttgacctga tgccaacctg gaggagtcca agaagttgaa ccattcccag
    15421 tttctttacg attcttgtac tgacgagtgg ccttagacaa gagggcatta gctacggttg
    15481 gaacagtttc cttgcccact gtctttgttt tattgtcagc gtagggctta cttgaaacct
    15541 tggcatctag atttgtttta ttaccattga cgataaaagc acctgagcca ttccactcca
    15601 gactcccctt tatttgactc ttgactgcgt ctgttaagac actctctgcc aatgcttgac
    15661 taggagcttc agacgcttgt tttttctgac taagattggt tttgggacta ttaggtgccg
    15721 acggcatctg cttgatataa tagctccctg tagacaaaag caataacact agcagtccga
    15781 ttagtgtctg tcttgttttt ttgttcatat ttctccttat ctttagaaaa aggctggttc
    15841 tccagcctaa tttcctgtaa atttatgaat caattcctgc cattttgctg gagacaggat
    15901 agcccatgga tcttgaccct tgcccaagat tccataacct accattaaac cgattcctag
    15961 agccagagta cctaaaatca gtactatgat gactaaaagt aaacgcttga ctacgtagct
    16021 tgatttctta ttcatcttca tcacttgcct caatccgctg aatcttagca cctagctgcg
    16081 ccaacttctc atggaaaccg tagtaacctc tatccaagtg aaccaattta ccgaccacag
    16141 tttctccctg tgctaccaaa cctgtcaaaa tcaaggctgc actggcacga aggtcagttg
    16201 aaagaacttc tgctccctgc aaaggctgtc caccaacaat acgagctgta tcacggataa
    16261 tctcagaatg caagcccatg cggcgcatct cttctaggtg ttggaaacga ttttcgaaaa
    16321 ctgtctccac catggttgat tcgccttttg caactgtcat caaggctgta aattgagcct
    16381 gcatatctgt tggaaatcct gggtggggca aggttttcac atgaacagct tttagatttt
    16441 ctagttgaga acgaacacga attccttcgt cttcttcaat tacttcaaca cccatttcaa
    16501 gtaacttggc aatcaaggga cggttgtgct cccagacagc gtctcgaatc aagacatcac
    16561 caccagtcat ggcagcagct accataaagg ttcctgcttc gatacggtct tggactacat
    16621 tgtgagtcgt accatgaagt ttctcaacac cagtaatggt tatagtctct gtaccagcac
    16681 ctttgacctt ggctcccatt tcattaagga gaatggctaa gtcaacaatc tcaggctcac
    16741 gcgcagcatt ctcaatcact gtcaccccat cagccagagt cgctgccatc atcaagttct
    16801 gcgttgcacc aacacttgga aagtccatat agatatgagc gccatgcaag cgttctgcct
    16861 tggcttcgat gtaaccagct gtctgactaa tcttaacccc catagcttcc agacctttca
    16921 aatgaagatc aataggacgg ctaccaatcg tacaaccacc tggcatggat accttggcat
    16981 gacccacacg ggcaaggatt ggccctaata caacgatgga ggcgcgcatc ttgctgacat
    17041 acttgtaagg ggcttcctca gtgatgtcgc cagtagcatc caccttgaca agatgagctt
    17101 cctcatcaaa gtcaaccttg gcattcaaac caccaactac ctgattcata ataaagacat
    17161 ccgacaaaat cggaacattc tgcaagacgg tctttccttc acttgctaga atagtcgctg
    17221 ccaacaaggg taagactgca ttttttgctc cctcgatcgt cacgcttcct accagacgat
    17281 tatcgccacc ttgaaccaca attttatcca tactcgtttc ctttactctt gatttcataa
    17341 taatcctcta agcgcttctt gccacaaatg atacaggcta ataaagaaag aactcaggat
    17401 gtagcctatg acaatgctaa aaaaggctac taataaacga acttttcttg tattctcatc
    17461 tgtcactttt aaaaccttct cccatctaac aagatccttt aaaaggtaaa aactcacata
    17521 aataaagagc atatgactac ttagagtgaa taataattga accatttgac tattatacca
    17581 tcttctctgt ttgtgcgcta gtttggaaac ttcactcaaa aattagggat tgtttttcaa
    17641 gtaatcaatc gcatcttgta gggttttaac gggcacgatt ttcatatccg tcttgattgt
    17701 tttagccgct tctagggctg tttggtagtt gtttttcgcg tccggatgcg ccttttgttc
    17761 ttcttcgcta acagggttat caggagcaaa gaaaatagca gcacctgccc tagccgaagc
    17821 tacaaccttc ttatcaatac ctccaatgtc tcccacatta ccatcgcggt caatggtacc
    17881 tgtaccggca acaatacgac cattacgaag atctgggtga gctatttgag tatagatagc
    17941 tagactaaac atgagaccag cacttggacc gccaatacca gctgttgaaa agctaattgg
    18001 gacattgctg attacctctg tacggtcaat caagccgatt ccaattccat ttttgccatt
    18061 ttccaaggtg ataatctttc cttctgcaga cttggtttgc ccatcctctt cataggtgac
    18121 cttgacggaa tcccctaatt tttgagaact gacgtaatca atcaagtctt tggaactatc
    18181 aaaggtctga tcattgactg ctgtgactgt atcagagata ttgagaatcc ctttaaaggt
    18241 tgaattatcc gtcacattca aaacataaac tccaaagtac ttgagttcga tatccttacc
    18301 agctgttttt agtccttgat acttggccat attttgcgat gtttgcatgt agaattgatt
    18361 gattcgcata aattcaacat cggaagaacc acctgtagtc tcctgagcac tacgaatatc
    18421 tgtaaaaggt gtcaaccaag cataaatcat atgagctaaa gtggcatgtt gaacaccaac
    18481 cgtaacgaat tgataggcac cagcttcctt atcttctgtg tcatttattt taaggacttg
    18541 gcgaatatct tccgaaccac ctggaacctc tatataataa ggcaagggca ctacaaatgc
    18601 caagaaagtc acaatcaagg ccgcaatgac gtataagggc catctaatct tttttttcat
    18661 ttcttatttc ctccaaaata ctctcgggaa catagcaggc aatatcccga ccaaacttca
    18721 aaagctctct aacgcctgat gaactgatat agagatgttc aggtcgacta tgtaaataaa
    18781 tagtctctat atcagaagac agctgatgat tgtagtaatc aaaactggct tcatattgca
    18841 aatccgacgc attcctcaaa ccacgcacta gacaagtagc acccaatctt tttgcaacat
    18901 cgaccaccaa ttcatcatga gaagccacga cttcaacatt ttccaaatgt cccaaagcct
    18961 tttctagccc ccgtttacga ttttcaagag ggagaaatcc ttgtttgtgg ggattaaaaa
    19021 aaatacccac ataaagctta tcaaaaagtc tgctcgcccg ttcaatgata tccagatgcc
    19081 catttgtcat cggatcaaat gagcctgtga ataagccaat cttatctgac atagactgtc
    19141 accttactaa ttccataaat cttttccttc cagataccca gacaggcaat ttcttctgga
    19201 agttcaacgg ctttatccgt ctcgcacaca accataacat cttcagaaaa aagctctctc
    19261 tcagccattt tttcaatatc tgctacgatt tgttccttgg catagggagg gtctaagaaa
    19321 acgaggtcaa attccccaga tacctgttcc aatgcccttt ctgcatccat ctttaggagt
    19381 tgaaattttc caacttcctt ggtcatctgg atattttcag ccacgatggt ctgagcctta
    19441 cggtctcgct ccaccaaaac agcactggac atgccacgcg atactgcttc gatagataaa
    19501 ccaccactac ctgcataaag gtccaagact cgtcccactt caaagtaggg accaatcatg
    19561 ttaaaaatgg ctcccctaac cttatccgaa gtaggtcttg tcgtcttgcc ttctagtgtc
    19621 ttgaggggac gtcccccata gattcctgat acgattttca tactgtttat tataccaaat
    19681 tatagacaaa aagagaaaga aaaccgaacc ttgcggttcg attctctaca aaatattttc
    19741 gtaagtatcg cggacttctt gaggccaaac acttgtttgc acttctccga tgtgtctctt
    19801 gcgaagtagg aacatggcca tacgagattg tccaattcct ccaccgattg tcaatgggaa
    19861 tagaccattc aacaaagact tgtgccattc caattccaag cggtcttcat cacctgtaat
    19921 ttccacctga cgtctaagag tttcttcatc tacacgaatt cccatagaag acaactcaaa
    19981 ggctccacct aaagactcat tccagacaag aatatcacca tttagaccct tgtagccatt
    20041 ctcagactcg cttgtccagt catcatagtc tggtgcacgt ccatcgtgcg gtttaccatc
    20101 tggcaactcg ccaccgatac caatcaaaaa gacggctcca aattctttac aaatcgcatt
    20161 ttcacgttct ttcggtgtca agtctgggta gcgttctacc aattcttctg tatggataaa
    20221 ggtgatttgt tttggcaaga tagactcgat gtcatagcgg gcttcaacag ctagctcagt
    20281 caggcgaata gccttataaa tcttctcaac tgtttctttt agataaacga tgttacgctt
    20341 accatttggg ataaccttct cccagtccca ctggtcaaca taaacagagt gggttgcatc
    20401 caaggaatcc tcatctggac gaagggcttt catgtggaca aagagaccct ctccttcacc
    20461 aaagccaaaa cgagccaagg tgtggcgttt ccatttagca agtgagtgca ccacttcata
    20521 agtagcatca gggatttgga gaaccttgac cgatactgga ttttccacac cagacaggtt
    20581 gtcctgcatt ccgtcaccga ccttactcaa gataggacct tgaacttcga caacttctag
    20641 cttatctttc aaatactggg taaaagtgtt tttgacaaag gaaatttctt cttgttgatg
    20701 gataaaactt ttcttcatag acaactcctc aaaaatttaa taaacgtatt atacacctat
    20761 ttccaagaaa agaaaagaga aaatttaaaa aaaatcagtg tcactcaaaa cactgatttc
    20821 atagaccttt tagtcattgc gaccaaagat acgtagaata cttaggaaaa gattgataaa
    20881 atcaagatag atgctgagag ccattgacac cacccagcct gtcgctacac gaccttgtga
    20941 ttgttcatag gcgaggcgaa tcttttggtt atcccaagca atcaaccctg aaaaaaccaa
    21001 aaccatggct acgctaatca tataatcaaa gaagccacta gccaagaaaa tattgactac
    21061 catagcaatc agtaaaccaa tgagagctgc catcattgct cgaccaatcc cactcaagtc
    21121 tttcttggta aaaataccaa ctgccgccat gacaaagaag agaagggcgc tcgatacaaa
    21181 ggcagataaa actgtacccg gagtatagaa agccaccaca aaactaaggg taaagccgtt
    21241 taaaacggag taaagtaaaa atactggaag agcagctgga ctatttcttg aagccatgct
    21301 actggcaacg aaaaccaaag ccaactccgc aaaagtagca atggtcaacc agagacgccc
    21361 ctgcatcaaa aagtaaacca actgagactg aaagaccgtc aacataaggc ctgataccaa
    21421 agcagatagt ccgattccca gaccaacaaa ggcataaacc ttagcgtaaa attgattgag
    21481 acctgcacgg tcatgtataa tagtgtgatt catccatttc tccttttctg tgaacatctt
    21541 tccttgatta taacaaaaaa agttaaaatt agcttaaatg gaagattaaa ataccggctg
    21601 caaccgcaac attcaaactc tcggcctgcc ccttcatgct aatatggacc aactggtctg
    21661 cactttcagc cataagggga ctaattcctt gaccctcatt tcccataact agtacaaaat
    21721 tttctataga aggcagttct ctgtaatcaa cagaatcttt agatagggtt gttgctagca
    21781 ctgggatagc taccttttta gtttcgtcaa gaagcgcttg actagtcatc cggtaaatgg
    21841 gcagatggaa atgactacct tgcatggaac gtagggtttt gagactgtag atgtctgccg
    21901 acttatctga aacaatcact cctgtaaaac ctgctgcatc cgcagttcga atgatagttc
    21961 ctacattacc aggatcttgc acatcttcca aaaacaagaa cttgccctga ctcaaatcag
    22021 cttgtcctac ttcttctttt tgaaccacgg caacaattcc ctgtggagtc tgagaatccg
    22081 ccaaatctag caaaatatcc tctgacaccc agacagtttg cgaaaaagta gctaactgat
    22141 ctcgataatt ttctagggca aagattttct caatcgtcac tccagcttgg acagcttctt
    22201 caaacaagtg ccagccttca atcaagtagg cagacttgcg gtattttttt tggcgtaatt
    22261 tcttggcatt ttttaccaca gaattggctt ttgaggttat aatagtcata gaaatattat
    22321 aacacaatca aaggggtttg gtatgcaaaa ggttagaatg attgcccaag gtagggtaca
    22381 gggagtcggc tttcgttggg gtgtttacag cttggcactt gaaattggtg gcatcacagg
    22441 tcgagtatgg aataacgacg atggcacagt ggaaatctta gcccaagcag actcatctgc
    22501 tatcatggca aaatttatcc aagaaatccg aaaaggaccg acaccttttt caaaagtaag
    22561 ctacttagat gtcaaactaa gcaactttcc tccctactct gactttaaaa tcgcaaatta
    22621 ggtctccaga actattgtat attttgtaaa aaaacagtag aatagaaagg tataattttt
    22681 aaagaaggaa taaaaacagt gaaatctatt aaacgttttg cactctcagc tatgggagcg
    22741 gctatgttgc ttgtcttgac tggttgtgtc aatgtcgata aaaccacagg tcagccaaca
    22801 ggatttattt ggaataccat cggagcccct atggctgaag ctatcaagta cttcgctact
    22861 gataaaggtc taggctttgg tgtcgctatc atcatcgtaa ccattatcgt gcgcttgatt
    22921 atcttgccac ttggtatcta ccaatcatgg aaggcaacgc ttcactctga aaagatgaac
    22981 gccctcaagc acgtccttga gccacaccaa acgcgtctca aagaagcgac tactcaagaa
    23041 gaaaaactcg aagcccaaca agctctcttt gctgctcaaa aagagcacgg tatcagcatg
    23101 tttggcggtg taggatgttt ccctatcctc cttcaaatgc ctttcttctc tgctatctac
    23161 tttgctgccc aacatactga aggggttgct caagcaagct acctaggcat tcctctaggt
    23221 tctccaagta tgattttggt tgcctgtgct ggtgtccttt actatcttca atcgctcctt
    23281 tcacttcacg gagtagaaga tgaaatgcaa agagaacaaa tcaagaaaat gatttacatg
    23341 agcccactca tgatcgtcgt cttctccctc ttctcaccag ctagtgtcac actttactgg
    23401 gttgtcggtg gtttcatgat gattctccaa cagtttatcg tcaactatat cgttcgtcca
    23461 aaacttcgca aaaaagtccg tgaagaacta gccaagaacc caccaaaagc aagtgctttc
    23521 tctaaaccaa gtggacgaaa agacgttacc cctgaacaac caactgctat cacaagcaag
    23581 aaaaaacaca aaaatcgcaa cgctggaaaa caacgttcga gataagaaga aaaaggctta
    23641 gctgatttgc taagtctttt tgcaaatcaa aagcccgatg tttccatcag gcttcttttc
    23701 tatccatgta cacgtttcat ataatcttga taactttcgg tatccatgag ttttttagcg
    23761 ttcttgacgc gatctgctgt tggtggtttg actccttcga gggaatatgg aattccaagt
    23821 tcacgccact tgaactcacc catggtgtga taaggtagaa tttcaaactt atcaacattt
    23881 ttgagggtct tgacgaactt accaagttca atcaagtcat catctctgtc tgtcaatcct
    23941 ggaactagca cgtggcgaat ccagacaggt tttccaatat ctgatagata ctgggcacaa
    24001 gccaagatat ttttattggt ttgtctagtg acaatcttgt gctgttcttc gttgatttcc
    24061 ttgatatcca aaagaaccaa gtcagtgaca gccatgagtt tgtcaaactt ctcaaggtaa
    24121 cgtggtttat tacggaaagg aagagcacag gtatccaagg tacagtggat tccttgttcc
    24181 ttagccttgg tgaagagagc aatcaggaaa tcaatctgca agagagcttc tcctccactg
    24241 actgtaatcc cacccttatt tccccagaaa ccacggtagc gcaaggcctc tgtcaagaca
    24301 tcatctaccg tccgttcacg tgacttattg gactccatag cccaagtgtc tgggttgtgg
    24361 caatactggc aacgcatgtg acagccctgc aaaaagacaa taaagcgaat accaggccca
    24421 tctactgacc caaagctttc tgtcgaatgc accattcctg tcacttgtcc ataatcaatt
    24481 gtttcttcag acatatcgtt accttccttg aaaacgtttt atagttttat tatatcacga
    24541 cttgaaggaa aaacaagatt tttgcctatt ttttagaaag caatctgttt ttcaatttca
    24601 ttttcaatct attatcagat tattcttcaa aatcgaagcc atataaggtt gcaaaatagt
    24661 cctcagggcg ctctgcacgg cggatttgac gggctttacc ttcttcggta tagaggattt
    24721 ccgcagaacg taatttggca ttatactggt agcccattga aaatccgtgg gcacctgtat
    24781 catgaattac cagcaaatca ccgatttctg tatgaggcag ttcgcgattg actgcaaatt
    24841 tatcattgtt ttcacagagt gaaccaacca catctaccgc ttcagctggt ccatctggat
    24901 gggtcacgtt gctaatatga tggtaagctc cgtacatagc tggacgcatg aggttgactg
    24961 ctgaggcatc cacacctaga taggtacggt aggtttcctt cttatgagtc actcttgtga
    25021 ctagagcacc gtgaggtgcc agcataaaac gacccaattc ggtgaaaatc ttgacctgac
    25081 caagacctgc tgacgtaaga acttcttcat acaccttacg aactccctca ccaatcaagg
    25141 cgatatcgtt cggctcctgg tctggacgat aattaacacc aataccgcca gaaagattga
    25201 taaagtctag ccaaatgccc aacttttcct tgatttcaac agccagttca aagagctgac
    25261 gagccaactc tggataatag agatgggtca cggtattgga cgctaggaag gagtgaatcc
    25321 caaaagtctt ggctcctttt tccttcaaga tagcaaaggc ttcaaagagc tggtccttgg
    25381 tcatgccaaa cttagcctcc ccaggattgt ccataatgtc tgtccccagt tcaaaaacgc
    25441 ctccaggatt ataacgacaa gagatgattt ctggaatgcc tgctactctc tccagatgtt
    25501 caatatcttc aaaggcatcc aagttaatgg tcgcacccaa ttcacgtgca taggcgtatt
    25561 ccttgtctgg cgtgttgttg gaagagaaca taatctcaga acccagaaag tccagtttat
    25621 ggctcatcaa aagctctaca taactagagc agtccacacc acaaccttct tcttggagaa
    25681 ttttcaaaat agctggagtt ggagtagcct taactgcaaa atattcctta aagcccttgt
    25741 tccacgaaaa agcttggttg acggctcttg ccttctcacg aatccccttc tcatcataca
    25801 agtgaaaggg agtcgggaac tcggcaacaa tcgcttctaa ctcttctcta ttgataaatg
    25861 gtgttttcat aagcttcctt ctattctgtt tgcaaagaaa ggctgggaca atcgttccaa
    25921 cctttagttc tatctcttat ttatcttcgt caaagatatt gccaacctca acatcgatgg
    25981 cttggttctt gacatcaata ttagttacct tcaagagtga cttgtagtca aactgctttt
    26041 cacgttcttc ttgggcattg tccgcaaaga ccgctacacc tgccagttct gagtcgaact
    26101 cgcgcaagag actaatcata ccgttgaccg ttccgccacc tttcaagaag tcatccacaa
    26161 tcaagacacg gctacctgcc ttaagactac gttttgaaag gaacattttc tcgatacggt
    26221 caccacttga acctgaaaca tagttgacgc taacagttga accttcggta attttcaggt
    26281 cacggcgcac aatgacaaaa gagacattga ggacattggc aactgcattt gcaagtggca
    26341 cacccttagt tgctacggtc ataaccgcgt caattttttg gtccataaag cttttggcaa
    26401 taatacgacc aatatttttc aagatggctg gtgtgctaag caaatcagac agatagatat
    26461 aaccacctgg caagatacgg tcactttctg acaacttggt acgcaagtct tcaaccattt
    26521 ccttagcatc ctgactcgaa atagacggtg tgaagatgac acctccgcca gccccagtca
    26581 ctgtctggat atgaccgatt tcaatttcct caaaggcgcg tttgataatg acgatatctt
    26641 ctgagatgga tgatttagca gactcatact tttcagcaaa agtattgaga ctagttagtt
    26701 tataaggatt attaatcaaa tagttggaaa tgacaaccat ccgatcactt cttcttaatt
    26761 tcatttctat ttcctattcc atttttattc aaaaaatcaa aaagcaaact agaaagctgg
    26821 tcgctggtgg ttcaaaacac tgttttgaga ttgtcaatag aactgacaaa ccctgtaata
    26881 tacctgcata tatacatacg acaaggcgat actaccctag tttgaagaga ttttcgaaga
    26941 gtattcattt ttgtctttta cttattatac catattcaca taaaaaaacg aacattctta
    27001 tcctaaaaaa tgctcatttt tcttaaatta ttaatctaaa tctggtttat agaaggaacg
    27061 attatccata gcgaagattt tattggtcat ctctccttta tccaccaaag caagagctgt
    27121 tgacatcatc atcatgcttg catccagatt gtcaatcata tggataatct ctgcttccat
    27181 aatgcgtgga cggactgggc ttccatactc aagcaagccg tggtgactga ggatgacatg
    27241 acgaagcaaa acgacttctt ccttggtatc atcgatgccg agttccataa ctgtcttggt
    27301 aatttcgcta tcaatgagag cgatatgtcc aagaagatta cctcgcactg tgtactctgt
    27361 ctggtctggc cccgtcaact cgatgacctt agctaagtca tgcaacataa tccccgcata
    27421 gagcaggctc ttattgagct gaggataaac ttcgctaata gcgtctgcca aacgcaccat
    27481 ggtcgccgta tgataggcca agcccgtttc aaaggcatgg tggttggtct tggcagctgg
    27541 ataggagtag aattccttat catacttggt gtagagattt cggacaatcc gttgccagac
    27601 aggattttca attttgaaaa tcatttgcga catgtagtca cgaatttcct tgacatcaac
    27661 tggtgacttg accttgaaat cggctgggtc attgggttca ccagcttgag gcaggcggag
    27721 agtaatttga ttgacttgag gggtattgtt ataaacttct cggcgtcctt tcatgtggac
    27781 aaccttacct gcggtaaagg cctcaatgtt atgaggttgg gcatcccaga gcttcccatc
    27841 aatctcgcca ctatcatctt ggaaggtaaa ggctaggtag tttttcccag ctcgagtttg
    27901 cctcaggtca gctgatttga ttaggtaaaa gccttcaaat agctcatctt ttttcatgtg
    27961 actaatcttc atattcttcc tcattttctt gaaaatggag tagatcaagc gcaggctcgc
    28021 cttctgacaa ctcaatgtga cggagcgtcc gctcgatagc tatggtacga cggtttaata
    28081 attcatcaat attgccagag gcatgttgga gatgtttttg tgccttgacc agaataccac
    28141 caaacttgcc aaactcggtc ttgacactgg caagagtctt gctgatatgg tcggcactct
    28201 tttggatatt aagggtcttg aaaccaactg atagggagtt aagaagggct gatagggtac
    28261 ttggtcctgc aacgataatc tgttcttccc gtctcaaatc atcaaagaag accggattgc
    28321 gcacaatctc tgaataaaga ccttctgtcg gaacaaacaa aactccaaaa ttggtcgtcc
    28381 gaggcggtgc tatgtacttg ctcttgatat ccttggcaaa gcgcttgacg cttgctagga
    28441 gtgacttacg acagcgttca atctcatcct tgtcacctgt ctcataggct tcttccaagc
    28501 ggtaataatc tgccagtgga aacttagagt caattggcag atagacgtat tcttggtcgc
    28561 cttgtccggg taacttgatg gcatactcca ctcgttcact agagttttca accgttgcgt
    28621 attctcgttc gtactgggca ggtgtcatga tgtcttcaat aatttgcccc agttgcaatt
    28681 ctcccagaat ccctcgcgtc ttggttccag agagaacctt gttaagagct ccgacatcac
    28741 gggcaactgt ctgcatttct ccaaggccac gattgacaga ctccagttgt ttagaaactg
    28801 tctcaaagga agcctgtaag cgtgtctgca aggtcttttc tagtttttcc tcgaccgtct
    28861 ggcgcatttg ttccaaacgt tgctcatttg attcctgcaa ggcttggaga cgttggtctg
    28921 tcttgtctct agtttggagg agattatctg tcatttcttg acggacttgg gtcagacctt
    28981 ggtgcaattc aatccgcact tcttgcaaac ggtcgctgac aaccacttcc aaatcttttt
    29041 ggtctaactg gctggcttgt ctggcttggt caaagcggta atccaactgg tctgacaaat
    29101 gatctgcctg atcctccaag ctcttactta agtgtttctc ctgcctatcc tgcctttgcc
    29161 aaatcagaaa gagaccagct aggttggcaa ttaataatag aataagtaaa ctttccatcc
    29221 tacctcctgt ccttgctatg cagtacgacc acataaccat ctgggcaagt taccgacact
    29281 tccctatcta tatattcgtt agaagcgtac acttttttaa agaaaaaatt ttcctctgtc
    29341 aactcatact tggctccaag aatagtcagc tggctatccc gaactggcat aaaggctaga
    29401 tagtcgtagt ctgaacgagg ttctagctga ctggtccctt ctggacaata agtaatcaag
    29461 ttttgcccat cctcaatttc tatttgatgc atatagggtg ccaacttagg attgctaggc
    29521 agaaagacat tggccaacat atggtcaata cggccaccca aggcaccgaa aatagtaacc
    29581 tgagcctgag gatttttctc aaagatggtt aagagagcca attccaaatc ggtatcatct
    29641 ttttctggtc gggcttggac aaaatgctgg gcacgttttt gaatcacctg tcgctcttct
    29701 tcggtcacag aatcaaaatc cccaactgct agagcaagaa gcaagtcttc ttccaagacc
    29761 cagagcgagc ctcgatccac cccaacaaaa gcatcaaaat ctgtccgata atgaccgcgg
    29821 tctccgcctg caaaaacggc aaccctagtc cagttgtttt ctgagagttt gtactcgctc
    29881 attgacatct cccttaaaga cataggaacc tgctacaaaa acggtcgcac cagcttcttt
    29941 ggcttgggca atagtttggt catcaatccc accatccact tcgatttcaa agttcaaacc
    30001 tttttcctca cgaagagcaa ccaactcacg aaccttatcc atggtttctg gcagaaaggc
    30061 ttgcccacca aaacctggat taaccgtcat gactaaaact tggtcaacta gatgaaggac
    30121 gtgcttgatg gcttcaactg atgtgccagg attgataacg actgaaggct taactccgag
    30181 tgaacgaatt ttttggaggg cgccatgaat atgaggcgtt gcttctacat ggatactgat
    30241 gatgtctgca cctgcacgcg caaaatcttc cagatgatgc tcagggtttg acaccatcaa
    30301 gtggcaatcg aaaaccatct tactatgagg acgaaggctc tcgaccacac ctgcaccaaa
    30361 actgatttgc ggtacaaaat gactgtccat gatatcgata tgggcatatt ctgccccagt
    30421 tgcttctaga cgtttgattt cacgttcaaa gttggcataa tctgctgcca gaattgacgg
    30481 agcaatcttg tattgagaca taggtttctc cttattttgg aatttttttg ctgacttttt
    30541 tataggtttc tctacgattt tcaatttcac taaggaattg caggtaattg tcaaaacgga
    30601 aggttgcaat aacaccctct tcaacagctg gtttgacggc acaagacggc tcatgggtat
    30661 gggtacaagt acggaactta caatctcggc taacagtagc aatctctgga aaggcctgat
    30721 tgaggtcttc agcccttgat acttcatagt ccagagatga aaagcctggt gtatctgcga
    30781 ttttaccccc gttgagattg taaaaactaa cagctcgagt ggtatggcga ccgcgaccta
    30841 gactgtctga aatttctccc gtttcaagat tgaggtctgg tgcgatttta ttgagaagag
    30901 ttgacttccc aacacctgtc tgccccataa agaccgtaac cttgcctgtt aacaaagaca
    30961 ggagttcctc tttactggtc acaaagtcat agccgatgtc accataggtc tgctggtaaa
    31021 aatccagttc tcccctatct tccaacaaat ccattttgga aatatagaca atgggatgga
    31081 tgcccttgtg ctccaaaaga accaagaaac gatccagcaa attgctgtta aaatcaggtt
    31141 ccttgacgga catgattact acagcttgat cgatattgac aataggcgga cgaaccagac
    31201 tgtttttccg ttcgtgaatt ttgaggatat agccttctga attttcctcg gcagagaaat
    31261 ctacccagtc cccaacataa ggggtatggc cttttttacg gaaattccca cgcgcgcgtg
    31321 tttgataaac ctggccatca ctctccacat agtagaaacc tgccaaggct ttaatgattt
    31381 gtccctgcat cttagagtcc ttgcccttta agtgcgtctg ctagaccggc aaattctgcc
    31441 aagctgagag cttccccacg cacacttggt gacaagcctg cctggtccaa agccttggtc
    31501 agcttgtcct tgacctcttc agtcttacca aagtaacctg tcaagttatt ccacaaggtc
    31561 ttgcggcgat gggtaaaact agccttggaa accttaaaga aaaagttctc atcttctact
    31621 gctacggctg gctctggacg acgcaccatt ttcaagatgg ctgaatccac atttggcgct
    31681 ggcacaaaga ccgtacgagg cacgataaag gcaaccttgg ctgtcatgta atactgcacg
    31741 gcgatagaca agctaccgta agccttggtg ttaggctggg ctgaaatgcg gtccgctact
    31801 tctttctgca tcatgaccac aaactcacaa aaaggaatgc cactctcaat caagtgcatg
    31861 agaataggcg tcgtgatgta gtaaggcaaa ttagccacta ccttgattgg caggttagga
    31921 tttttaaaat tttggatatg ttgcgccaaa tcaaccttga gaatatcttc gttaactacg
    31981 gtcacattat caaaatcacg cagagtatct gccaaaattg gcatcaaacg gtggtcaatc
    32041 tcaaaagcca tgacttgggc tgcacgctca gccaaaaatt ctgtcaaggc accaatacct
    32101 ggcccgattt cgatgacatt gacctgatca tcaatttcag ccgtatccac aattttttga
    32161 aggatattgg tatccgtcaa gaaattttgc ccaaaggact ttttaaaggt aaaaccgtga
    32221 cgctccaaca ctgccttggt cacgctataa tctgcaattc tcatctattc tcttttctat
    32281 tatctgttac tactattgta acacattccc cttgtatttt gggaatgaaa atcataccaa
    32341 aaaactatct ttcctcatga agaaagatag tcttggaaat ctttaaagag ggacttagtg
    32401 cttctctcga aacatacgtt catactcttc gaaaatctct tcaaaccacg tcagcttcac
    32461 cttgccgtac tcaagtacag cctgcggcta gcttcctagt ttgctctttg attttcattg
    32521 agtatcaaaa aaatcagctt cttgataact tcgattttcg ggtagggtca aatccacatc
    32581 ctcctccaca tcatccactg tcagttcaac cgtctgaggt aaatttttca aacgataatg
    32641 cttttgcctt tgcccttcaa tactagcaaa atcaagcaaa tagccatgca ctcggatttg
    32701 aaccaaaagg agatgattgg tcatattttc catgatgagg atatcttcta aaccacctct
    32761 ggcactagga taatcagata ccctgcgaat acggattttt tcacacatga gcaagtttcc
    32821 tcatatcaat gatttcatca gccttattcc agactagggg attatgggtc gcaatgatga
    32881 taattcgatt ttcatctttc aaatccacca agagattcat aacctcctct gaattttcag
    32941 gatcaagagc tgctgttggt tcatctgcca aaatcaaggg tggatttttc aaaatagtct
    33001 tagcaagggc aactcgttgg gcctctcccc cagataaagt ataaattttt tgttctaaat
    33061 ccaaataccc tagattaact ttttctaaag cccccacttg cctttccaaa cgttctactt
    33121 ttgagatttt ctgaccaaca aaacccaaat ccaaattttc tttgattgat tggttttcta
    33181 agaggccgaa attttgaaag agatagccca tctggtctcg aaaatactca cgagtaggaa
    33241 tggtttttaa atctttcccc tgatagagaa cccttccacc atctatcttt tctagctttc
    33301 ccaagatatt cagcagcgtc gtctttccgc ttccactctt tccgattaag gcataaacct
    33361 tgcccttctc cagcttgaga ttcaaaccag agaaaatcgc gcggtcatta aatttctttt
    33421 ccaatccttg aatatcaatc atcttatttt cctttcaata ctgccatgct accagcttct
    33481 tcttttttat cctgccttac taaaatcaag agggcgttaa gcgtaaacaa agctacaact
    33541 agagcgctaa tcaaaccatc tcttgtcaaa atactagata ggactaggcc aagcaagaga
    33601 actcctcctt gcgccagtaa atacttgcca tgaagctcat agattgtcat accagcaaga
    33661 cgtttaatca taagttcccg tctgaactgc tcaaaataga gaagattcat ggaatcaaat
    33721 aacaagatag ccgtagacag ggtcaaaatc gtcccaataa ggagagagta aaactccacc
    33781 cgtttgtcat ttagtacctt ggcaaaaaat agctggcttt ttaccaagta agaaaccttg
    33841 tgatacagac cttgctcttt tagagctgtg atgctgtctc catatcgatc tagtttcaag
    33901 gcactattag ccgtagttcc ccacaacatc cctgcaacag gtcttgttcc agtcgcttgc
    33961 ggcgttagaa ctacaataat cggatctttt aggtactggc gtgttgtctt gtacccatca
    34021 ttatagagga aacgttcctg tcctgtttct gtaaaagcta gccttacctg tgggaggtag
    34081 tgtttctgac tcgtcacttc tacactttca gatgaaaagt tttgcaggta atctgtaaac
    34141 aatccttggt agtaggcaga ctgctctcgc aagctctcag gcaagatcag cccaaactct
    34201 ccctcagaca agttttgcat cttgtccata aactctgaag aaacggtaat cttttcttct
    34261 atcagatagc gcggcgagac atagataaca ttccctaacg gtgtgtagtc actgagacga
    34321 ttgccatcta ggtccacttc tgctccatct gagaaattgt caacattgct cataatataa
    34381 aaagagtctg tattggctaa ccgttcttca gtaaatgtct gccactcacg attatcctta
    34441 cgcgttcctt cttcatcggc aaatgcacta gaccaaccaa aggatagacg gtaacggtct
    34501 gaggactggc tccatttatt gctagctctc tccatttcct gcatttcacg gtagtggggt
    34561 aggagagctg tcgcactcga tccgaccacc aatacagcta agagttgccc caccatcatc
    34621 aatgtcatca tacgtttgag agggagtttc cctttcaata gatccaccag actattttcc
    34681 tgtaaaccaa gtagatagac gacacttagt aaggtagaaa tccctgccaa ggtcaatcca
    34741 taaagtagaa gagcaatgat gaccagttgt accgttgcca taaacaaggc accttgatac
    34801 cagagaatcc ccaatcccaa aagactggat accagcactg agcagataag ctgtctcaca
    34861 tcttctaaca ctggtctgag agcaactcca aacaagctct caccagctat taagcgaatc
    34921 cctgcctgac gaagggattt gatccgataa atcagggtca gactcataaa ggtcagcaga
    34981 aaaatagcta aactcagtag caccataggg gtggccgcca atagtaagac tatcgaaaat
    35041 ggatcttctc cattcgaaac aaagccttga taaccaagct ctttcaaggt ggtctgtaag
    35101 ctcactccat ccaaacttcc tgacacaatc aagtaagacc ctaataaatc actcgtttct
    35161 gcactctcct tggaggaaat ggtcagacct tctggaagct ctccctcacc ataagtggca
    35221 taggtaaaga gtgtttctcc agcttcattt ggctcaacga ttcgacgggc gatgagacta
    35281 ttatgctcta ccgccaagtg actcaaagcc tctgtcacct cttcgcgact agctactggt
    35341 tgatttatca tcattcctgt cacatcaaca gaaggatagt taccaaataa aatctcttct
    35401 cgatggtcaa cggaagttat caccatataa agcgatacca ataccattga aatcaaaata
    35461 aataaacgtt tcatcatttc ctccaaaaag ttacttggtc acttagtgag aaggtgacca
    35521 agtaaagcta aacaataggg ctataccatt ctaaacatta tagtagaatg caactttctc
    35581 tccccaagaa gtacgaatcc atgcacgaga agtccctcca gcaccagcat atcccttgtc
    35641 agatgaacca gtttttctgc taacaactgt tgaactatgg tattttgaag ggtgatagta
    35701 gtttgagtaa gcaccaccgt tacctgaacc ataagtccaa acaccacctt ctgggtattg
    35761 aacggctgca gaggcaactg atacacctcc acctaatgtt gctgcaatgc tcgctacaag
    35821 agctaacttt ttaactgttt gtttcatatt gatactcctc tatttttgat tacaagattg
    35881 ttgagttact tgctcctctt tccattatca acgttgatac tattatatta ccaaatgata
    35941 ttctaaaatt atttgttttt ctctaaattg tcaaaatagc accctgaaat gaacttttat
    36001 agtcattata ctccatcttt atcacactat caaggacatc aatgtcctta aaatctaact
    36061 atttcatatt atttttagct tatatctaaa aaaacagttc taaagacgaa ctttagaact
    36121 gttttgatac gaggacaagg acatttttgt cactgattca ctatgtttat aaatattttt
    36181 tgacatcctc ttgccattcc tctgtcaatt tctttactag aaatccatct ccaattagct
    36241 tcgcaaatgt tttagaagac tgataaaatg attcagctaa actaaaatct ctttctactc
    36301 ttaatgcttg cttccacaaa aacataaata caagaggttt cttttgataa tcttgagttt
    36361 tatccataat ttcttgtaaa cacgatagat aatcattaaa acaatcagtt actcctacct
    36421 tttcaagaca acacattcct gaaataagag tatctctaat tataaagaag ttttctaatt
    36481 tagttacctt tttctgttcc aaaagaaaga gcattagctt ttcgatttga tttataaatt
    36541 tggcaagatc ttttctaatg agcatttgat aaaaaaacaa acgaatcaac aacatatcat
    36601 ttgttgaata aacttctttt tctatgatct gagacatatg ttcctcaagt attaactctg
    36661 catattcagg ccttctagtt ctagaagtat ccaaacacgc ctgcaatact tcacatgcta
    36721 attgttcttc tttaggaaga ttatcaaagt atgttttata aatctcttcc aaacacgctt
    36781 ctttcttatc atactcctct tctttaccat agattggttc acgtaaaatc tggtatttca
    36841 attctaaata agcagaagga agagctgaaa aatccggcat aaggctataa actggaactc
    36901 ctagccggcg agcaatatag gctaacttgg gcaaactcgg ttgcgaagct ccactttcaa
    36961 ttcgcgacag ttgacgaact gtcagttctt gctcatctcc acaaaaatct ggacgactaa
    37021 ttcctttttc tatccgaatc tctttaattt tttgaccaat taacatcaga cgcctcctct
    37081 tctacctgct tcgaaaaata ctgtgaaact taaaaaattg taacggctac atctttccta
    37141 ctcataagat ttcatagctt cttccacttc tgccaaagta accccaaaca actctaggcg
    37201 tttgaggagt tgcttgccat tagaatagcc gattcggaga gtctctccga gatattctct
    37261 acgcttacgg ctgtctgccc ctgctagaaa accaaggcga atcaagtcgc tacgactaat
    37321 gtcaaactga ctctcatgtt caaattgttc tgtcacctga gctagagccg ttttcaggtc
    37381 ttcatagctg gcatgctcaa ttcccagaga acgccccttg gtcttggact tgggaacagc
    37441 ttcatctcgc ttgagaaagg catgctgaac tgttggaatg gccgtcataa tcatgcgccg
    37501 aatccgctcc ccattaaaat ctgggtctgt aaagacaatg actccatgac gttggtgtag
    37561 acgctgaatt cgctctatat cctgatcatt gatggcagaa cctcgtgtct cataggtctc
    37621 cacatcgaaa taacgcttga gattgaccgt atcatagcga ccttcaacca cgataacttg
    37681 agaaattttc tctttcatta cttgctgtcc aatccaaaaa ttcgttctgc atttgcagtc
    37741 gttgctaccg ccagctcttc tgtcgtcata ccacgcaagt cagcgataaa gtcgaccaca
    37801 tagcgagtat aggctgtttt attttcacga ccacgcttgg gtacaggtgc taagtaaggc
    37861 gcatctgttt ccaccaacat cttgtccaaa ggtaactctt tagctgcttc ttggaggtca
    37921 gttgccttct tgaaagtcac cactcctgag aaggaaatgg tcataccaag atccacaaac
    37981 ttctctgccc actcaagcgt ccctgaaaat gaatgcatga taccaccacg aggaccaacg
    38041 ccctcactct tgataatctc ataggtatct tccagcgcat cacgggtatg gacaacaaaa
    38101 ggcaaatcca agtccttaga tagctgaatc tgacggcgaa aaacctgctc ctgcacctct
    38161 ttgggcgctg tcatccaatg gtagtctaag ccaatttcac ctaaagccac aaccttggaa
    38221 tgttttaact tatccaacaa gtaagcctca acttcctctg tataagtacc agcttctgta
    38281 ggatgccaac caatagtcgc atagagctgc tcatactcat ctaccaactc caaggcacgc
    38341 tcaatcgtcg gtttatcaaa accaacaata ttcatctgta tcacacccat ctcagcagcc
    38401 aaggcaattt cttctgcctc acgacctgca aattcttcta cattcaagtg tgtatgtgta
    38461 tcaaaaatca tctcttctaa cctcgttttc tatcttctat tataccaaaa aagaggaggg
    38521 gcacctaatt tttcggtttc ccctcctctc ttcaatagag agctattctg ctatcttttc
    38581 tatccgatat tgcccatctc ctattccaca gttagagaca gaagagattg gctacattga
    38641 tagaatattc ctattcagct aaagtatgtg attatcttgg gttctcactt ttctcaccca
    38701 tcactaggat tgatgacttc tcaaaatccc ccttataatc taactttaag tagagaatag
    38761 aattttctag ctgttctatt ttctacgtct agtctttctt cctagcaaag caaaaccact
    38821 tgttgccacc actagaccaa gactagcaag tgctgcactt gatgctgaac ctgtgttagg
    38881 taattgtttg ccagcaggtg actggtaggt aacatcttgc attgttcctg cagttgcttg
    38941 cggtgcactt gttgtcttag gagcagcatt aggagccact ggtctcttag gaactgtaac
    39001 catggcaatg gcttgcactc caatcgtttc tgcttccttc acatcttcca tagttttcgc
    39061 attttcaatc tctttgagag ctgcttgttt ttctgcttcc actcttgcta aaagttctgc
    39121 tttttcttta tcagaaagcg gtgcgccttt gatttcatcc tgcttatcct tggctgcttt
    39181 ttcaatggca tttttagctg attctttttc agtagctaat tgcttagaag cttgtgattg
    39241 agctgagttt tgtgaacctg tgtgagctga tccacccgcc tggctaccac cgccttcatt
    39301 cgcattagca tctgagcttc cagtattgcc tcccttatct ccacctggta tagtttctag
    39361 cttatactct agtgtagctt cttgagttac agattcacct ttcgcagatt gttgaactgt
    39421 atcttttcct agaatcgtca ctactgaacc atctgggaat gtgattgttg ctgtaccatc
    39481 tccagctaca ttgattgtcg ctccgtctaa tgctgaacca tttgcttgta aaatagcaac
    39541 cttaactttt tcttcatctg ttaaatgagt tatatctttt acatctactc tttgagcagg
    39601 tgctttaaca gttgattttt cagcagtcgg tttagtgcta tcttgtgctt ttggatcttg
    39661 tgctaccaat tgatttcctg gaattgtaat agctgaacca tctttaaaga cgattgttgc
    39721 tgtaccatct ccacctactt caactttata gtaaaataaa ataataacag gacaaatcga
    39781 tcaggacagt caaatcgatt tctaacaatg ttttagaaac agaggtgtac tattctagtt
    39841 tcaatctact ataacatcgc ttccgaatcc atttgcatct actgaacttt tttacaaaaa
    39901 taaaaatcag tagactcgag ttcctactga tttttgatag aattcgtttg gattatgcag
    39961 ccaaaacttt gcgtccttta cgacgacgag ctgccaatac gcgacgacca tttttagttg
    40021 acatacggtt acggaatccg tgtttacgcg cacgacgaag tttacttggt tgataagtac
    40081 gtttcacgat gaatacctcc tcatagattt tgtattcgtt tagccggcta taaagtgatc
    40141 agttactaaa catactttac tattctatct gattctttca cttttgtcaa tagctctagg
    40201 caaatgtttc cagctttttc gaatgcaagc cct
//
LOCUS       DAVLBE010000015        38853 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.015, whole genome shotgun sequence.
ACCESSION   DAVLBE010000015 DAVLBE010000000
VERSION     DAVLBE010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 38853)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38853)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38853
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.015"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            <1..910
                     /locus_tag="VXB91_000819"
     CDS             <1..910
                     /locus_tag="VXB91_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HEV0470299.1"
                     /translation="QAGSLRASTSQQNETIASQNAAASQTQAEIGNLISQTEAKIRDY
                     QTAKSAIETGTSLAGQNLAYSLYQSYKSQGEENPQTKVQAVAQVEAQISQLESSLATY
                     RVQYAGSGTQQAYASGLSSQLESLKSQHLAKVGQELTLLAQKILEAESGKKVQGNLLD
                     KGKITASEDGVLHLNPETSDSSMVAEGALLAQLYPSLEREGKAKLTAYLSSKDVARIK
                     VGDSVRYTTTHDAGNQLFLDSTITSIDATATKTEKGNFFKIEAETNLTSEQAEKLRYG
                     VEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            1080..1787
                     /locus_tag="VXB91_000820"
     CDS             1080..1787
                     /locus_tag="VXB91_000820"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEV0470300.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAG
                     KGVLNNQISSFIFEKLNAAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIADDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQGLK"
     gene            1844..5569
                     /locus_tag="VXB91_000821"
     CDS             1844..5569
                     /locus_tag="VXB91_000821"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HEV0470301.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNLGLSSLKSIRIVQVYDV
                     FDLVEDLFAPAEKHIFSEQVTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDATELEAVKNYLLNPVDSRFKDITIGIAKQEFS
                     ESDKTIPKLPFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTATHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDTFVA
                     ECNKENIDAVVVATVTEKPNLVMHWNGETIVDLERRFLDINGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTIFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLV
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFAQFEASQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELKTALTAQLGGFVFTSPEEIAGVEKIG
                     QTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVPAVASDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVRVAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEDANNTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            5662..7104
                     /locus_tag="VXB91_000822"
     CDS             5662..7104
                     /locus_tag="VXB91_000822"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HEV0470302.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGQLKRHRDMGLLSEVFRNPANLDKLTGAGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNAASLKKELEQRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGAEWI
                     RDLKPGEIVIIDDEGIQYDSYTDDTQLAICSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSLTYLSIDGLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            7141..8163
                     /locus_tag="VXB91_000823"
     CDS             7141..8163
                     /locus_tag="VXB91_000823"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HEV0470303.1"
                     /translation="MTNKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLASSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            8160..8705
                     /gene="purN"
                     /locus_tag="VXB91_000824"
     CDS             8160..8705
                     /gene="purN"
                     /locus_tag="VXB91_000824"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HEV0470304.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKTDYEAALVELLEEHQIDLVCLAGYMKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYPEVVKALFTD"
     gene            8789..9298
                     /locus_tag="VXB91_000825"
     CDS             8789..9298
                     /locus_tag="VXB91_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEV0470305.1"
                     /translation="MLESKKTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLISFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEC
                     LQYILAIGITDITDLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            9323..10870
                     /gene="purH"
                     /locus_tag="VXB91_000826"
     CDS             9323..10870
                     /gene="purH"
                     /locus_tag="VXB91_000826"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HEV0470306.1"
                     /translation="MTKRVLISVSDKAGIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     DTIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAAKDNKIELIDLVVVNL
                     YPFKETILKPDVTYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAAN
                     GETSYETRQRLAAKVFRHTAAYDALIAEYFTAQVGESKPEKLTLTYDLKQPMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHM
                     NPCGIGQADDIETAWDYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLNGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQEFIEAADKYGLTMVFT
                     GVRHFRH"
     gene            10992..12254
                     /gene="purD"
                     /locus_tag="VXB91_000827"
     CDS             10992..12254
                     /gene="purD"
                     /locus_tag="VXB91_000827"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HEV0470307.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHYKLIDFAKANDIAWTFIGPDDALAAGIVDDFHAAGLKAFGPTRLAAELEW
                     SKDFAKEIMVKYGVSTAAYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVAETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFLEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPVLEGMIKEGRPYLGVLYAGLILT
                     ADGPKVIEFNARFGDPETQIILPRLTSDFAQNITDILDSKEPNIMWTDKGVTLGVVVA
                     SKGYPLDYERGVELPAKTEGDVITYYAGAKFAENSRALLSNGGRVYMLVTTADTVKEA
                     QASIYQELSQQKIEGLFYRTDIGSKAIK"
     gene            12657..13145
                     /gene="purE"
                     /locus_tag="VXB91_000828"
     CDS             12657..13145
                     /gene="purE"
                     /locus_tag="VXB91_000828"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000805607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HEV0470308.1"
                     /translation="MKPVISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTPD
                     LMFKHAEEARSRGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGVDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALFALRLLSVEDKSIADALANFAEEQGKIAEESSNE
                     LI"
     gene            13132..14205
                     /gene="purK"
                     /locus_tag="VXB91_000829"
     CDS             13132..14205
                     /gene="purK"
                     /locus_tag="VXB91_000829"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HEV0470309.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPASRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDAVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSLDLADIDLSKNYVLKTATGGYDGHGQKVIRSEAD
                     LEAAYALADSADCVLEEFVNFDLEISVIVSGNGKEVTFFPVQENIHRNNILSKTIVPA
                     RISESLVDKAKAMAVRIAEQLNLSGTLCVEMFATDDDVIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPVIKLHAPAVMLNVLGQHVEAAEKYVTENSSAHLHMYGKIE
                     AKHNRKMGHVTLISNEPDSVGEF"
     gene            14228..16615
                     /locus_tag="VXB91_000830"
     CDS             14228..16615
                     /locus_tag="VXB91_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001839381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEV0470310.1"
                     /translation="MFEKIKGINIKSGIFEDETKLELFEGNFEGTNPVQNDRASLLFG
                     RNGSGKSTIARGINQLKNGEIGTDRVSFIDKNNNNIVLSDTERKSIFVFNEHYVDQKV
                     KIAQEGLDTIVILGEQVDIDEELDRLRTQLSESQIESQDYYAEYEEYLDEKNEKSPDF
                     WKKEMTDSLKGVGNWAERDREIKGNRAASPVHNNTFQNFVDLQPILDKNELEVEFNNK
                     KARYFSIRDSAVTINNELSLPDINFDSNELSTLLSEKIEEPELNSRDKYLLTLLSDST
                     KGERHLREVKDFFEDEHQKKCPFCTQSVSEDVKVELTNGITKLLSRAVEEHQSALRGK
                     KIDEINQDFSGYEQIDPILIQSYQNSINALNAKFNEINSIIDKKIDNPYNIVELPNIS
                     FSQELSQAEHDIEKINQAIIKHNSEISGIQKLKVDLLQINNELAFYEIQDAYKKFQEK
                     TNKKAICENNYNNSSKRVKDYEKQISDLEDKKLNIDIAVDEINKSLNYIFFSKNRLAI
                     QNQNGKYYLLSRGKSVVPSRVSVGERNALALCYFFTEIIQQRELADAYSHEYFIVIDD
                     PISSFDMENKVGITSYLKYCLTRFFKGNSNTRVLLMTHDKQTIYDFDIFLKEIMESCK
                     EEEGGQKSKYKKLELVSGKLQEFKTSTHDYTELLEIVFGYALGNSTPTSESFVGNAMR
                     KILEAYGSFNYKKGIAELTTDPLIVEKIDKEYRTYFENLMYRLVLNGESHFKDPVKTL
                     SIDFFDTISDEERKKTARDLLVLLYLLDDLHVLKHLEGVSNAENRLEQWKCEILE"
     gene            16788..18086
                     /gene="purB"
                     /locus_tag="VXB91_000831"
     CDS             16788..18086
                     /gene="purB"
                     /locus_tag="VXB91_000831"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HEV0470311.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEINEIFNPIYYTKRVDDIFERLGLGD"
     gene            complement(18141..22079)
                     /gene="strH"
                     /locus_tag="VXB91_000832"
     CDS             complement(18141..22079)
                     /gene="strH"
                     /locus_tag="VXB91_000832"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEV0470312.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTPTTTEN
                     QPTIHTVSDSPQSSENRTEETPKAELQPEAPKTVETETPATDKVASLPKTEEKPQEEV
                     SSTPSDKAEVVTPTSAEKETANKKEEEASPKKEEAKEVDSKESNTDKTDKDKPAKKDE
                     AKAEADKPETETGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTD
                     LHLLVGNDGLRFMLDDMSITANGKTYASDDVKRAIEKGTNDYYNDPNGNHLTESQMTD
                     LINYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKKSARTVDLDNEQAV
                     AFTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYE
                     KFIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVAS
                     SKLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIP
                     IIGGMVAAWADTPSARYSPSRLFKLMRHFANANAEYFAADYESAEQALNEVPKDLNRY
                     TAESVTAVKEAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLTPEAQKEEEAKR
                     EVEKLAKNKVISIDAGRKYFTLDQLKRIVDKASELGYSDVHLLLGNDGLRFLLNDMTI
                     TANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSP
                     GHMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKI
                     FNFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYE
                     DKDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYVIGNHKQDEAY
                     PLSKAVENSGKVPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFA
                     DHNKDYFRANYNALREELAKIPTNLEGYSKESLEALDAAKTALNYNLNRNKQAELDTL
                     VANLKAALQGLKPAATHSGSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAG
                     QENIITAGVKGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGAPVTHKGDESG
                     LAPTTEVKPRLDIQKEEIPFTTVTRENPLLLKGKTQVITKGVNGHRSNFYSVSTSADG
                     KEVKTLVNSVVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPRLEIPSQPAPSTAPA
                     EESKALPQDPAPVVTEKKLPETGTHDSAGLVVAGLMSTLAAYGLTKRKED"
     gene            complement(22394..23110)
                     /locus_tag="VXB91_000833"
     CDS             complement(22394..23110)
                     /locus_tag="VXB91_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV0470313.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIKFISCDRDH"
     gene            23458..25245
                     /locus_tag="VXB91_000834"
     CDS             23458..25245
                     /locus_tag="VXB91_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HEV0470314.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRIPPEDWYHSLYNLKAL
                     GFNTVETYVAWNLHEPREGEFHFEGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPAYIEAVGRYYDQLLPRLVPRLLNNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEECGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            25242..25718
                     /locus_tag="VXB91_000835"
     CDS             25242..25718
                     /locus_tag="VXB91_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEV0470315.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            25746..26651
                     /locus_tag="VXB91_000836"
     CDS             25746..26651
                     /locus_tag="VXB91_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEV0470316.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            26638..27453
                     /locus_tag="VXB91_000837"
     CDS             26638..27453
                     /locus_tag="VXB91_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV0470317.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALTLSALGHFALGM"
     gene            27460..27864
                     /locus_tag="VXB91_000838"
     CDS             27460..27864
                     /locus_tag="VXB91_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0470318.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIGGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKSRAAESIVKVNDLLAGFDDDEDE"
     gene            28162..29328
                     /locus_tag="VXB91_000839"
     CDS             28162..29328
                     /locus_tag="VXB91_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEV0470319.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVANPAT
                     YLKKDVATVLVSFARSGNSPESVATVDLAKSLVDELYQVTITCAADGKLALQAHGDDR
                     NLLLLQPAVSNDAGFAMTSSFTSMMLTALLVFDPTEFAVKSERFEVVSSLARKVLDKA
                     EDVKKLVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INDNTVVLVFGTTTDYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVALDCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEYQK"
     gene            29444..30481
                     /locus_tag="VXB91_000840"
     CDS             29444..30481
                     /locus_tag="VXB91_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HEV0470320.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTDGTGGFPGNLKIWISYHLEETGAYEI
                     SYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSIAPDGVPAKTPEAN
                     RDVVKHIYNGALLKDIFAEEDEQIQLASGLDHPFALPAGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            30688..31542
                     /locus_tag="VXB91_000841"
     CDS             30688..31542
                     /locus_tag="VXB91_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV0470321.1"
                     /translation="MTYEYKSHIYLAETVLNVKDLASQTAFYQQVIGLEILSQTETES
                     ILGLGGKVLVQLIQAQESGEVREHYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEAIYLEDLEGNGIELYRDKPVSTWDIREDGRIIGVTEALAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSSQFYQKVLGLEDKFSVPSASWIAAGDYHHHLAVNEW
                     GGKGLASRKQGLPGLAYYVIEVAHKKELLTIAQRAQEVDAPIKWMTSSQLEITDSDGI
                     VTRIRLAR"
     gene            31692..31949
                     /locus_tag="VXB91_000842"
     CDS             31692..31949
                     /locus_tag="VXB91_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HEV0470322.1"
                     /translation="MTNSKYITCLKRSEGQLCGIQKMIEGDRDCADLVTQLTAVRSSV
                     ERVIEMIITENLTECINQPLDDSEAQKERLEKAIRYLIKRK"
     gene            complement(31991..32308)
                     /locus_tag="VXB91_000843"
     CDS             complement(31991..32308)
                     /locus_tag="VXB91_000843"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0470323.1"
                     /translation="MKIKVQTRKLAAGCSKHCFKVVDRTDEVSNHIYGKVKLTWFEEI
                     FEEYKSPHNKTHTIKVFMYCPPKVRQKKSNFWGQYISIPDTMRFFNFKDFLQLLLTHI
                     KLF"
     gene            complement(32380..32658)
                     /locus_tag="VXB91_000844"
     CDS             complement(32380..32658)
                     /locus_tag="VXB91_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV0470324.1"
                     /translation="METSISMADFYGKYQNENLELIDVREAHEFQAGHAPGAKNLPLS
                     TLEQGYKELKPDHEYYVICQGGVRSASTCQFLSSQGLTVTNVEGGMNA"
     gene            32880..33644
                     /locus_tag="VXB91_000845"
     CDS             32880..33644
                     /locus_tag="VXB91_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HEV0470325.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLGEEI
                     DRYAREVGANCVGEFVSATKTYPVYVINYKGEEVCLAQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPCRYMEMQPEAIAAIEEVLE
                     DRGIPYEEVMTWTTDGFYRETAEKVAYRKEEGCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLDQYDSRDWGSEAFNKALELSLASVHHL"
     gene            complement(33884..34126)
                     /locus_tag="VXB91_000846"
     CDS             complement(33884..34126)
                     /locus_tag="VXB91_000846"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0470326.1"
                     /translation="MKTKASIRKLVTGCSKHCFEVVDRTDEVSSKHCFEVADKTDEVS
                     SKHCFEVADKTDEVSSKHCFEVADRTDEVSNIYTAR"
     gene            34344..35723
                     /locus_tag="VXB91_000847"
     CDS             34344..35723
                     /locus_tag="VXB91_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEV0470327.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIAPRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLI
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
     gene            35737..36402
                     /locus_tag="VXB91_000848"
     CDS             35737..36402
                     /locus_tag="VXB91_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HEV0470328.1"
                     /translation="MSDRTIGILGLGIFGSSVLAVLAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            36516..36611
                     /locus_tag="VXB91_000849"
                     /pseudo
     CDS             36516..36611
                     /locus_tag="VXB91_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            36757..37296
                     /locus_tag="VXB91_000850"
     CDS             36757..37296
                     /locus_tag="VXB91_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV0470329.1"
                     /translation="MKLLSIAISSYNAAAYLHYCVESLVIGGEQVGILIINDGSQDQT
                     QEIAECLASKYPNIVRAIYQENKGHGGAVNRGLAEASGRYFKVVDSDDWVDPRAYLKI
                     LETLQEFESKGQEVDVFVTNFVYEKEGQSCKKSMSYDSVLPVRQIFGWDQVGNFSKGQ
                     YIMMHSLIYRTDLLRASQF"
     gene            37363..37773
                     /locus_tag="VXB91_000851"
     CDS             37363..37773
                     /locus_tag="VXB91_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HEV0470330.1"
                     /translation="MYYLPVDFYRYLIGREDQSVNEQVMIKCIDQQLKVNRLLVDQLY
                     LSQVSHPKMREYLLNHIEITTVISSTLLNRSGTAEHLAKKRQLWTYIQQKNPEVFQAI
                     RKTMLSRLTKHSVLPDRKLSNVVYQITKSVYGFN"
     gene            37889..>38853
                     /gene="pavB"
                     /locus_tag="VXB91_000852"
     CDS             37889..>38853
                     /gene="pavB"
                     /locus_tag="VXB91_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HEV0470331.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADV
                     VNPTPGQVLPEETSGTKEGDLSEKPGDTVLTQAKPEGVTGNTNSLPTPTERTEVSEET
                     NSSSLDTLFEKDEEAQENPELTDALKETVDTADVDGTQASPAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLKASDNAPWSDNGTAK
                     NPALPPLEGLTKGKYFYEVDLNGNTVGKQGQALIDQLRANGTQTYKATVKVYGNKDGK
                     ADLTNLVATKNVDININGLVAKETVEKAVKDNVKDSIDVPAAYLE"
BASE COUNT        11013 a         7399 c         8909 g        11532 t
ORIGIN      
        1 tcaagcaggc agtcttaggg ctagtacatc gcaacaaaat gagaccatcg cgtcccagaa
       61 tgcagcagct agccaaaccc aagccgaaat cggcaacctc atcagtcaaa cagaggctaa
      121 aattcgcgat taccagacag ctaagtcagc tattgaaaca ggtacttcct tggccggtca
      181 gaatctagcc tactctcttt accagtccta caagtctcag ggcgaggaaa atccccaaac
      241 taaggttcag gcagttgcac aggttgaagc acagatttct cagttagaat ctagtcttgc
      301 tacttaccgt gtccagtatg caggttcagg tacccagcaa gcctatgcgt cagggttaag
      361 cagtcaattg gaatccctta aatcccaaca cttggcaaag gttggtcagg aattgaccct
      421 tctagcccag aaaatcttgg aggcagagtc aggtaagaag gtacagggaa atcttttaga
      481 caaggggaaa attacggcaa gtgaggatgg ggtgcttcat cttaatcctg agaccagtga
      541 ttctagcatg gttgcagaag gtgccctact agcccaactt tatccatctt tggaaagaga
      601 agggaaagcc aaactcacag cctatctaag ttcaaaagat gtagcaagaa tcaaggtcgg
      661 tgattctgtt cgctatacta cgactcatga tgccgggaat caactttttc tagattctac
      721 tattacaagt attgatgcga cagctactaa gactgagaaa gggaatttct ttaaaatcga
      781 ggcggagact aatctaactt cggagcaggc tgaaaaactt aggtacgggg tggaaggccg
      841 tctacagatg attacgggca agaaaagtta tctacgttat tatttggatc aatttttgaa
      901 caaagagtaa tgttcgtgtt tttagagtta aataattttt aaactgtgag aaagattctt
      961 cttgcagttt tttctttaca atttttgaaa aacatctgct atttattcgg ttaaattctt
     1021 gtgttttttg gttttttgtg gtaaaatgtg ctcaagtaat acgaaaggcg aactttaaaa
     1081 tgtcaaaaca attgatctat tcgggaaaag ctaaagatat ctatacaact gaggatgaaa
     1141 atcttattat ttcaacttac aaggaccagg cgactgcttt caatggtgtc aagaaggagc
     1201 agattgcagg taagggagtc ttgaataatc agatttcatc ttttattttt gagaaattaa
     1261 atgcggctgg tgtggcgact cactttgtgg agaaactttc agacacggaa caactcaata
     1321 aaaaggttaa gattattcct ttggaagtcg tgctccgcaa ctatactgct ggttcctttt
     1381 caaaacgttt tggtgtggat gagggaatcg ccttggagac tccgattgtc gaattttact
     1441 acaaaaatga tgatttggat gatccattta tcaatgatga gcatgtaaaa ttcctacaga
     1501 ttgcggatga ccagcagatt gcctacttga aggaagaaac gcgtcgtatc aatgaactat
     1561 tgaaagtctg gtttgctgag attgggctta aattgattga ctttaagcta gagttcggtt
     1621 ttgacaagga tggcaagatt atcttggcag acgaattttc accagataac tgccgcttgt
     1681 gggatgctga tggcaaccac atggataagg atgttttccg tagaggattg ggagaactaa
     1741 ccgacgttta tgagattgtt tgggaaaagt tgcagggttt aaaataacaa cctcaaggct
     1801 gtttgggaat attgcaagag ctgaaataaa ggaataagaa ttgatggata aacgtatttt
     1861 tgttgaaaaa aaggctgatt ttcaggtcaa gtcagagagt ttggttagag agctccagca
     1921 caacttggga ctgtcaagct tgaaaagtat tcgtattgtg caagtatatg atgtatttga
     1981 cttggttgag gacttgtttg cacctgcaga gaagcacatt ttctctgagc aggtaaccga
     2041 ccatgtttta gatgaagtat ctgtgcaggc ggatcttgct aactatgctt tctttgccat
     2101 tgaaagtcta ccagggcagt ttgaccagcg tgcagcttcg tcacaggaag ccttgctttt
     2161 gttgggaagt tcgagtgacg tgacagtcaa cacagcccaa ctttacttgg tgaataaaga
     2221 tattgatgcg actgagttgg aagctgtcaa aaactacctg ctcaatccag ttgattctcg
     2281 tttcaaggat atcacgatag ggattgccaa gcaggagttt tcagagtcag acaagaccat
     2341 tccaaaattg cctttctttg aaagctatac agcagaagac tttgctcgct acaaggccga
     2401 acaagggatg gccatggaag tggatgattt gctctttatc caagactact ttaagtcaat
     2461 cgggcgcgtg ccaactgaga ctgaactcaa ggttttggac acttactggt ctgaccactg
     2521 ccgtcatacg acttttgaga cagagttgaa acacatcgac ttttcagctt ctaaatttca
     2581 aaagcaattg cagtcaacct atgacaagta tattgccatg cgcgaggaat taggtcggtc
     2641 tgaaaaacca caaaccttga tggatatggc gactattttc ggtcgttatg agcgtgctaa
     2701 tggacgattg gatgatatgg aagtctctga cgaaatcaat gcctgctcag ttgaaattga
     2761 agtggacgtt gatggtgtca aggaaccttg gctcctcatg tttaaaaacg aaactcacaa
     2821 ccatccaaca gaaattgagc catttggtgg agcggctacc tgtatcggtg gagctattcg
     2881 tgatccgttg tcaggccgtt cctatgttta ccaagccatg cgtatttcag gtgctggtga
     2941 tattacagca ccgatttcgg aaactcgtgc tgggaaattg ccacaacaag tcatttctaa
     3001 aacagcaact catggttatt cttcatatgg taaccagatt gggcttgcca caacctacgt
     3061 tcgtgaatac ttccacccag gctttgtagc taaacgtatg gaacttggtg ccgttgttgg
     3121 tgcggctccc aagggcaatg ttgtccgtga aaaacctgaa gcaggtgatg tgatcatcct
     3181 tctcggaggt aaaacaggtc gtgatggtgt cggtggtgcg acgggctctt ctaaggttca
     3241 aacagttgag tctgtagaga ctgctggtgc tgaggttcaa aaaggaaatg ccatcgaaga
     3301 acgcaagatt cagcgcctct tccgtaatgg caatgtcact cgtctgatca agaagtccaa
     3361 tgactttggg gcaggcggtg tctgtgtggc tatcggtgaa ttggcagacg gtcttgaaat
     3421 cgacctcaac aaggtgcctc ttaaatacca gggcttgaat ggtacagaaa ttgccatctc
     3481 tgaatcacaa gaacggatgg cggtcgtggt tcgtcctgaa gatgtggata ccttcgttgc
     3541 cgaatgtaac aaagaaaata ttgatgctgt tgtggtggcg acagtaactg aaaaaccaaa
     3601 tcttgtcatg cactggaatg gtgagacaat cgttgacttg gagcgtcgtt tccttgacat
     3661 caatggtgtg cgcgtggttg tcgatgccaa agttgtggac aaggatgtca aactcccaga
     3721 agagcgtcaa acatctgctg aaacactgga atcagatacc cttacggttc tatctgacct
     3781 caaccatgca agtcaaaaag gattacagac tatctttgac tgctctgttg gacgctcaac
     3841 ggttaatcac ccacttggtg gtcgttacca actcacacca actgaggcat ctgtgcagaa
     3901 attgccagtt caacacggtg tgactcatac tgcgtcggtc attgctcaag gtttcaaccc
     3961 atatgtagct gaatggtctc cataccacgg tgctgcttat gcggttatcg aagcaactgc
     4021 tcgtttggtg gctgctggtg ccaactggtc caaggctcgt ttctcttacc aagaatattt
     4081 cgagcgtatg gacaagcaag cagagcgttt tggtcagcca gtagccgctc ttctaggctc
     4141 tattgaagct cagattcaac ttggcttgcc atctatcggt ggtaaggact ccatgtctgg
     4201 tacctttgaa gaattgaccg ttccgccaac cttggttgcc tttggggtga cgacggcaga
     4261 tagccgtaag gtgctctctc cagaatttaa agctgttggg gaaaatatct actacatccc
     4321 aggtcaagcc ctctctgcag agattgattt tgacttgatt aagaaaaatt ttgctcagtt
     4381 tgaagcaagc caagctgacc ataaagtgac atctgcatca gctgtcaaat acggtggtgt
     4441 agttgaaagt ttggctcttg ctacctttgg aaactatatt ggtgcagagg tgaccttgcc
     4501 tgaacttaaa acagctttga cagctcaatt aggcggcttt gtcttcacat ctcctgaaga
     4561 aattgctgga gtagagaaga ttggacaaac gaaagcagac tttacactga ctgtcaacgg
     4621 tgtgaagcta gatggacaca agcttgacag tgcatttcaa gggacattgg aagaagttta
     4681 cccaacagaa tttacccaag cgaaagaact agaagaagta ccagctgtgg catcagatgt
     4741 tgtgattaaa gccaaagaaa aggttgaaaa acctgtggtt tacatcccag tctttccagg
     4801 aaccaactca gaatatgatt cagctaaggc cttcgaaaaa gaaggtgcag aggtcaattt
     4861 ggtgccattc gtgaccttga atgaagaagc tattgtcaag tcagttgaaa ctatggttga
     4921 caatatcgac aagactaata ttctcttctt tgctggtgga ttctcggctg cggatgaacc
     4981 agatggttca gctaagttta tcgtcaatat cctgcttaat gaaaaagtgc gtgtggctat
     5041 tgatagcttt atcgcccgtg gtggtttgat tatcggtatt tgtaatggat tccaagcctt
     5101 agtcaaatcg ggtctcctac cctacggaaa ctttgaagat gctaacaata ctagcccaac
     5161 cctcttctac aatgatgcca accaacacgt ggccaagatg gtggaaactc gcattgccaa
     5221 taccaactca ccatggttgg ctggtgtgca agtgggcgat atccacgcta ttcctgtttc
     5281 gcacggtgaa gggaagtttg tcgtgacggc tgaggaattt gcagagctcc gtgacaatgg
     5341 acaaattttc agccaatacg ttgactttaa cggtaaacca agtatggatt ctaagtacaa
     5401 tccgaatggt tctgtccatg ccatcgaagg aattaccagc aagaatggtc aaatcatcgg
     5461 taagatgggc cactcagaac gttatgagga tggtcttttc caaaatatcc caggcaataa
     5521 agaccaacac ctgttcgcat cagcggttaa acatttcact ggaaaataag acttacagat
     5581 tttctaatag atagtatcag taatgtaaaa gtcatgtaaa tctagctctt gatgattaca
     5641 aatgaaaatt aggtataaaa aatgacatac gaagtaaaat ctcttaatga agaatgtggt
     5701 gttttcggta tttggggaca tccagatgct gctaagttga cctattttgg actccacagt
     5761 cttcaacacc gtggtcagga gggggcagga atcctctcca atgatcaagg acaactgaag
     5821 cgccatcgtg acatggggct tttatcagaa gttttcagaa atccagccaa tttggataaa
     5881 ttgacaggag ctggtgcgat tgggcatgtg cgttatgcga ctgctggcga agcttctgtt
     5941 gataacatcc agcccttcct cttccgtttt cacgatatgc agtttggctt ggctcataat
     6001 ggaaatctga ccaatgcagc ctctctcaag aaagaactgg aacaaagagg agcaattttc
     6061 agcgcgactt cggactctga aatcttggct cacctcattc gtcgcagtca taatcctagc
     6121 ctgatgggca aaatcaagga agcgctcagc cttgtcaaag gtggttttgc ctatatcttg
     6181 ctgtttgagg acaagttgat tgcggctctt gaccctaatg gctttcgtcc gctttctatc
     6241 gggaaaatgg ccaacggagc ggtggttgtt tcctctgaaa cctgtgcttt tgaggtcatt
     6301 ggtgccgagt ggattcgtga tttgaagcca ggtgagattg tgatcattga tgacgagggc
     6361 attcagtatg acagctatac agatgatact cagttggcga tttgttctat ggagtatatc
     6421 tactttgctc gccctgattc taatatccac ggtgtcaatg tccatacggc acgtaagaga
     6481 atgggagcgc aattggcgcg agaatttaag catgaggcag atattgtagt tggtgtgccc
     6541 aattcttccc taagcgcggc tatgggattt gcggaagaat caggcttacc aaatgaaatg
     6601 ggtctgatca aaaaccaata cacccagcga acttttatcc aaccgactca agaattgcgg
     6661 gagcaaggag tgcggatgaa actgtctgct gtttcgggtg ttgtcaaagg caaacgtgtg
     6721 gtcatggtgg atgattccat tgtacgtgga acaacctctc gtcgtatcgt tcagctcttg
     6781 aaagaagcgg gtgcgactga ggttcacgtt gccattggaa gtcctgcact agcgtatcca
     6841 tgtttctacg ggattgatat ccagacccgt caggagctga ttgcagccaa tcatacggtc
     6901 gaagaaactc gccaaatcat tggtgcggac agtctgactt atctttcaat tgatggcttg
     6961 attgagtcga ttggtatcga aacagatgcg ccgaacggtg gtctctgtgt cgcttacttt
     7021 gacggtgact acccaacgcc tctctatgac tacgaagaag actatcgtag aagtttggaa
     7081 gaaaagacca gtttttacaa gtaggcgaca gattctccat taaagaaaag gaaaaaacaa
     7141 atgacaaata aaaatgcata tgcccagtcg ggtgtggatg ttgaagcggg ttatgaagtt
     7201 gttgaacgga ttaaaaagca cgtggcccgt acggagcgtg caggtgtcat gggagctctt
     7261 ggtggctttg gtggtatgtt tgacctttcc aagactgggg ttaaagaacc cgtcttgatt
     7321 tcagggactg acggtgtcgg aaccaagctc atgttggcta tcaagtacga caagcacgat
     7381 accatcgggc aggactgtgt ggccatgtgt gtcaacgaca tcattgctgc aggtgcggaa
     7441 cccctctatt ttctcgacta cgtagcgaca gggaagaatg aaccagctaa gctagaacaa
     7501 gtggttgctg gtgtggcaga aggttgtgtg caggctggtg ctgccctcat cggtggggaa
     7561 acggctgaaa tgccgggcat gtacggcgaa gacgactatg acttggctgg ttttgcggtc
     7621 ggtgtggctg aaaaatctca aatcattgac ggttcaaagg tggtagaggg agatgttctt
     7681 ctcggacttg cttcaagtgg gattcactca aatggttact ctttggttcg tcgtgtcttt
     7741 gcggattaca caggtgagga agtcctacca gaattggaag gcaagaaact taaggaagtt
     7801 ctacttgagc cgactcgtat ctatgtcaag gctgtcttgc cgctcatcaa agaagagttg
     7861 gtcaacggca ttgcccacat cacaggtggt ggctttatcg aaaatgtccc tcgtatgttt
     7921 gcagatgacc tagctgctga aattgatgaa agcaaagttc cagtgcttcc aattttcaaa
     7981 gcccttgaaa aatatggtca gattaaacac gaagaaatgt ttgaaatctt caatatgggt
     8041 gtgggactta tgttggcggt cagccctgaa aatgtagagc gtgtaaaaga attgttggat
     8101 gaagcagtct atgaaattgg tcgcatcgtc aagaaagaaa acgaaagtgt cattatcaaa
     8161 tgaaaaaaat agcggttttt gcctctggta atggctcaaa ttttcaggtg attgccgaag
     8221 aatttccagt ggagtttgtc ttttcagacc atcgtgatgc ctatgtgctt gagcgtgcaa
     8281 agcagctcgg cgttctgtcc tatgcttttg aactcaagga gtttgagagc aagacagact
     8341 acgaagcagc ccttgtcgaa ctcttggaag aacaccagat tgacttggtt tgcctagcag
     8401 gctacatgaa aatcgttgga ccaaccttat tgtcggctta tgaaggtcgg attgtcaaca
     8461 ttcatccagc ctacttgcca gaatttccag gagctcatgg gattgaggat gcttggaatg
     8521 ctggcgtggg tcagtctggt gtgaccattc actgggtgga ttcgggtgtg gatacaggcc
     8581 aggtcatcaa acaggttcgt gtgccacgac tagctgatga taccattgac agatttgaag
     8641 ctcgcatcca tgaagcagag tacaggttgt atccggaagt agtgaaggct ctatttacag
     8701 attgactttt tgatgattca tatgatatct ttgattttaa attggagtca gtgtttgttg
     8761 aagacggctt caaacggagg tatttgtaat gttagaatct aaaaaaacaa ctcgatatgt
     8821 attttatgtc tatctgatgt tattaacttg gggaatctta tttaagtttg aaacaaatcc
     8881 tgaatttata gcatttttct tagctccaag gtatatcaat tggattccat tttcagaacc
     8941 actaatagtc gatggaaaaa ttgtttttgc tgaaatgtta tttaatctga tttcctttat
     9001 tccattaggt gtttgtttcc ctttgataaa aactaattta tctagtttaa gaatagtcgg
     9061 gacaggtttc ttgattagtt tattgtttga gtgcttacag tatattttag caataggtat
     9121 aacagatata acggatttga ctttaaatac gctaggtgtc tgtgtaggct tactgattta
     9181 tcaaattttt ataagagtgt tcaaatcaca gactagaaaa tggatcaata tcttaggtat
     9241 gcttagcctt ggttttgctt atcttgtttt actgttactg catttaattg gtgtttaact
     9301 aatgattaaa aaggagaata taatgactaa acgcgtctta atcagcgtct cagacaaagc
     9361 gggcattgtt gaatttgccc aagaactcaa aaaacttggt tgggagatta tctcaacagg
     9421 tggaactaag gttgcccttg ataatgctgg ggtggatacc attgctatcg atgatgtgac
     9481 tggtttccca gaaatgatgg acggtcgtgt gaagaccctc cacccaaata tccacggagg
     9541 gcttctcgct cgtcgtgact tggatagcca cttggaagcg gctaaggaca acaagattga
     9601 gctcattgac cttgtggtgg tcaaccttta cccatttaag gaaactatcc ttaaaccaga
     9661 tgtgacttat gctgatgcag ttgaaaatat cgatattggt gggccgtcta tgcttcgttc
     9721 agcagcgaaa aatcatgcca gtgttacagt tgtggtagat cctgctgact acgctgtggt
     9781 tttggacgaa ttggcagcaa acggcgaaac ctcttatgaa actcgccaac gtttagcagc
     9841 caaagtattt cgtcacacag cggcttatga cgccttgatt gcagaatact tcacagctca
     9901 agtgggtgaa agcaagcctg aaaaactcac tttgacttat gacctcaagc aaccaatgcg
     9961 ttacggtgag aatcctcaac aagacgcgga cttttaccag aaagctttgc ctacagatta
    10021 ctctattgct tcagccaaac agctcaacgg gaaagaattg tcatttaata atatccgtga
    10081 tgcagatgct gctatccgta tcatccgtga cttcaaagat agtccaaccg ttgtggctct
    10141 caaacacatg aatccatgtg gaattggtca agctgatgac atcgagactg cttgggacta
    10201 cgcttatgag tctgacccag tatctatctt tggtgggatt gtcgtcctca accgtgaggt
    10261 ggatgctgcg acagctgaga agatgcacgg cgttttcctc gaaatcatca ttgcaccaag
    10321 ctatacggat gaagcgctag ctattttgat caataaaaag aaaaacttgc gtatccttgc
    10381 cttgccattt aatgctcaag aggctagcga agtggaagca gaatacacag gtgtagtcgg
    10441 tggacttctc gtgcaaaatc aagacgtggt caaggaaagc ccagctgact ggcaagtggt
    10501 gaccaaacgt cagccaactg agacagaagc gactgctctt gagttcgctt ggaaggctat
    10561 caagtacgtc aaatcaaatg gtattatcgt gaccaacgac cacatgacac ttggtgttgg
    10621 tccaggtcaa accaaccgtg tggcttctgt tcgccttgcc attgaccaag ccaaagatcg
    10681 tctgaacggg gcggtccttg cttcagatgc cttcttccca tttgcggata acgtggaaga
    10741 aatcgccaaa gcaggaatta aggccatcat ccagcccggt ggctctgtcc gtgaccaaga
    10801 attcatcgaa gcagcggata aatacggctt gactatggtc tttacaggtg tgagacattt
    10861 tagacattaa gaagataaaa gggaagaaaa cagtttcttt ccttttttgg cttaaaatgc
    10921 taactgaaac aagattaaaa cgaacttttt tgatataatg ttggtaaata attcgcaaaa
    10981 gaggttgagg aatgaaactg cttgttgtcg gttctggtgg tcgtgagcat gcgattgcta
    11041 aaaagttact tgaatcaaaa gacgtggaaa aagtctttgt agctcctggg aatgacggta
    11101 tgactctgga tggtctggaa ttggtaaata tatctatttc cgaacattat aaattgattg
    11161 acttcgcaaa ggccaacgat attgcttgga cctttatcgg tccagatgac gcccttgcgg
    11221 ctggtatcgt ggatgatttc catgcagctg gtctcaaagc ctttggtccg acaagattgg
    11281 cagcggagct ggagtggtcc aaggatttcg ccaaggaaat catggtcaaa tatggtgttt
    11341 cgacagcagc ctatggcaca ttttcagatt tcgaggaagc aaaggcctat atcgaaaagc
    11401 atggtgcgcc tatcgtagtc aaggcggatg gcttggcgct tgggaagggt gtcgtcgttg
    11461 ctgagacggt tgagcaagcg gtcgaagccg ctcatgagat gcttttggac aataaatttg
    11521 gtgactcagg tgcgcgcgtg gttattgagg aattccttga aggagaggaa ttttcactct
    11581 ttgcctttgt caatggtgat aagttctaca tcatgccaac ggctcaggac cacaaacgtg
    11641 cctacgatgg cgacaaaggg cctaacacgg gtggtatggg tgcctatgcg ccagttccac
    11701 acttaccaca gagtgtagtt gatacagcgg ttgacaccat tgtcaagcca gttctagaag
    11761 ggatgattaa agaaggtcgc ccttatctgg gagttcttta cgcagggctt atcctgacag
    11821 ctgatggacc gaaagtcatt gagttcaacg ctcggttcgg agatccagaa actcagatta
    11881 tcttgcctcg cttgacctct gactttgctc aaaatatcac agatatcctg gatagcaagg
    11941 agccaaatat catgtggacg gacaagggtg tgactctggg tgtggttgtc gcatccaagg
    12001 gctacccgct agactatgaa aggggcgttg agttgccagc caagacagaa ggcgatgtca
    12061 tcacctacta tgcaggggct aagtttgcgg aaaatagcag agcactgctc tcaaacggcg
    12121 gacgagttta tatgctcgtt accacagcag ataccgtcaa agaagcccaa gccagcatct
    12181 accaagaact atcccaacaa aaaatagaag gactcttcta ccgaacagat atcggaagca
    12241 aggcaattaa gtaaagatat aagaataacg cgccgtagtc gccaaacacg ataatggtcg
    12301 tcgtggtgaa aagaccagaa cagtgaatgt tctggtcagg gggaaacttg gagaccgtag
    12361 gctcaaagtt taggaatgaa accgaaggtt tgcttccgcc tccatcacct aagaccatta
    12421 tcaaaaagaa aaataaaaat tcacaaaata cgttaatgat cgtatggttt gcgagcgtta
    12481 gcgagctaat atagaacaat caccgccgtt gtgaaagaac gattggatga taatccaatc
    12541 gttcagggaa attggaagac cttgggtttc caatttaggc atgagacacc tttggtggct
    12601 gctgccgtcc ctcacaagct aaggtgattg ttgaaaaaga ggaaaaagga gaagaaatga
    12661 aaccagtaat ttccatcatc atgggctcaa aatccgactg ggcaaccatg caaaaaacag
    12721 cagaagtcct agaccgcttc ggtgtagcct acgaaaagaa agttgtttcc gcacaccgta
    12781 caccagacct catgttcaaa catgcagaag aagcccgtag tcgtggcatc aagatcatca
    12841 tcgcaggtgc tggtggcgca gcgcatttgc caggcatggt agctgccaaa acaacccttc
    12901 cagtcattgg tgtgccagtc aagtctcgtg ctcttagtgg agtggattca ctctattcta
    12961 tcgttcagat gccgggtggg gtgcctgttg cgaccatggc tatcggtgaa gctggagcga
    13021 ctaacgcagc tctctttgcc ctccgtctcc tctctgtaga agataagtcc attgcggatg
    13081 cacttgccaa ctttgctgaa gaacaaggaa aaatcgcaga ggagtcgtca aatgagctca
    13141 tctaaaacaa tcggaattat cggtggcggt caactgggtc agatgatggc catttctgct
    13201 atctacatgg gccacaaggt tatcgcgctg gatcctgcgg cggattgccc ggcctctcgc
    13261 gtggcggaaa tcattgtggc accttataac gatgtggacg ccctccgtca gttggcagac
    13321 cgttgcgatg tcctcactta tgagtttgaa aatgtcgacg ctgacggttt ggatgccgtt
    13381 atcaaggatg gacaactccc tcaaggaaca gatctgctcc gcatttcgca aaatcgtatt
    13441 tttgaaaagg actttttgtc aaacaaggct caagtcactg tggcacccta caaggtcgtg
    13501 acttctagcc tagacttggc agatatcgac ttgtcgaaaa actatgtcct caagactgcg
    13561 actggtggct acgatggtca tggacaaaag gttattcgtt cagaagcaga cttggaagca
    13621 gcctatgcgc tagcagactc agcagactgc gtcttggaag aatttgtcaa ctttgacctt
    13681 gagatttctg tcatcgtgtc aggaaatggc aaggaggtga cgtttttccc agttcaggaa
    13741 aatatccacc gcaacaatat cctgtctaag accatcgtac cagcccgcat ttctgaaagt
    13801 ctagtagaca aggctaaagc tatggcagtg cgaatcgcag aacaactcaa cttgtctgga
    13861 actctctgtg tggaaatgtt tgcgactgat gatgacgtta ttgtcaatga aatcgcccca
    13921 cgaccacata actctgggca ctattctatt gaagcctgtg atttctctca gtttgacacc
    13981 catattctcg gtgttctcgg agcaccatta ccagtcatca aactccatgc gcctgccgtc
    14041 atgcttaacg ttctcggcca gcatgttgag gccgctgaaa aatatgtcac agaaaattca
    14101 agcgcccacc tccacatgta tggtaaaata gaagcgaagc acaaccgcaa gatgggacat
    14161 gtgactttga ttagtaatga accagatagt gtgggagagt tttaggggag aggggtctaa
    14221 agaaaaaatg tttgaaaaaa ttaaaggaat taatataaaa tcaggtattt ttgaagatga
    14281 aacaaaatta gaactctttg aaggaaattt tgagggaaca aatccagtac aaaacgatag
    14341 ggcaagttta ttgtttggaa ggaatggttc agggaaaagt accattgctc gaggaataaa
    14401 tcaattaaaa aatggtgaga ttggaacaga tagagtatca tttattgata aaaataataa
    14461 taatattgta cttagtgata ctgaacgaaa atcgatattt gttttcaatg aacactatgt
    14521 tgatcagaaa gtcaaaattg ctcaagaagg gttagataca attgtaattt taggtgaaca
    14581 ggttgatatc gatgaggaac tggatagatt aagaacgcag ttatcagaat cacaaattga
    14641 atctcaagat tattatgctg aatatgaaga atatttagat gaaaaaaatg aaaaatctcc
    14701 agatttttgg aaaaaggaaa tgacagattc tttgaaagga gtaggcaact gggccgaaag
    14761 agatagggag ataaaaggaa atcgagctgc atctcccgtt cataataata cctttcaaaa
    14821 ttttgttgat ttacaaccaa tcttagataa aaatgagtta gaggttgaat tcaacaataa
    14881 aaaagctaga tatttttcaa taagagattc cgcagttact ataaataatg aactatcttt
    14941 acctgatatt aattttgata gcaatgaatt atcaacttta ttgtctgaaa aaatcgaaga
    15001 acctgagttg aattctaggg ataagtattt actgacatta ttatctgatt ccacaaaagg
    15061 tgaacgtcat ttgagagaag ttaaagattt ctttgaagat gaacatcaaa aaaaatgtcc
    15121 tttctgtact caatcagtat cagaagatgt taaagttgaa ctcacgaatg gcataactaa
    15181 actactatca agagcagtcg aagaacacca atccgcattg agaggtaaaa aaattgatga
    15241 gattaatcaa gatttttctg gttatgaaca gatagatcca atattaattc agtcttatca
    15301 aaatagtatt aatgctttga atgctaaatt taacgaaatt aactcaataa tcgataagaa
    15361 gattgataat ccatataata tagttgagtt acctaatata agcttttctc aagaattaag
    15421 tcaagcagag catgatattg aaaaaattaa ccaagcaatt atcaaacata attcagaaat
    15481 ctcgggtatt caaaagttaa aagtagatct ccttcaaata aataatgaat tagcttttta
    15541 tgaaattcaa gatgcataca aaaagtttca agagaaaaca aataaaaaag caatttgtga
    15601 aaataattat aataacagta gtaaacgagt aaaggattat gagaagcaga tttctgattt
    15661 agaagacaag aaacttaata tagatattgc agttgatgaa attaataaaa gtttaaatta
    15721 catatttttt tcaaaaaatc ggttagctat acagaatcaa aacggaaaat actatctgtt
    15781 atcaagaggt aagtctgtgg tccccagtag ggtttccgta ggggaacgaa atgcgctggc
    15841 attatgttat ttctttactg agataattca acagagagag ttagcagatg cttatagtca
    15901 tgaatatttt attgttattg acgatccaat ttctagtttt gatatggaaa ataaagttgg
    15961 aataacctcg tatttaaaat attgtttaac tagatttttt aaggggaata gtaatactag
    16021 agttttacta atgacccatg ataaacaaac aatatatgac tttgatatct ttttgaaaga
    16081 gataatggaa tcctgtaaag aagaggaagg tggacaaaaa tctaaataca agaagttaga
    16141 attggtttct ggtaaattac aagaattcaa aactagtact cacgattata cagaactact
    16201 tgaaatagtc ttcggttatg cattgggaaa tagtacacct acttcggaaa gttttgttgg
    16261 gaatgcaatg agaaaaattt tagaagccta tggtagtttt aattataaga agggaattgc
    16321 cgagctaaca acagatcctt taattgttga aaaaattgat aaagaataca gaacttattt
    16381 tgagaatctt atgtatagac tggttttaaa cggtgaaagt cattttaagg atccggttaa
    16441 aactttgagt attgatttct ttgataccat ttctgatgaa gaacgaaaaa aaacagctag
    16501 agatttacta gttttgcttt atcttttaga tgatttacat gttttaaaac atttagaggg
    16561 tgtatcaaat gcggaaaata gacttgaaca atggaagtgt gagattttag aataagagaa
    16621 tcataccatt tgacttattg caatggttga agtttgcatg atagctgatt agagtaatca
    16681 aaggattatt acttcctaat tttattttct acaaacccta atttagcatc taataatgca
    16741 aagtttcctg agcctcatag ataaaaaaga tttttaagga gaaaaacatg atcaaccgtt
    16801 actctcgccc tgagatggcg aatatttgga gtgaagaaaa taaataccgt gcttggcttg
    16861 aggtggaaat cctctctgac gaggcatggg ctgagttggg ggaaatccct aaggaagatg
    16921 tggctttgat tcgcaagaag gcggactttg acatcgaccg tattttggaa attgagcagg
    16981 agacgcgcca cgatgtggtg gctttcacgc gtgcggtttc tgagactctt ggtgaagagc
    17041 gcaagtgggt tcactatggg ttaacttcta ccgacgtggt ggatactgcc tatggttacc
    17101 tctacaagca ggccaacgac atcatccgtc gtgaccttga aaacttcact aatatcatcg
    17161 ctgacaaggc caaggagcac aagttcacca tcatgatggg gcgtactcat ggtgtgcacg
    17221 ctgagccgac aacttttggt cttaaattgg caacttggta tagcgaaatg aaacgcaata
    17281 tcgagcgctt cgagcatgcg gctgctggtg tagaagctgg taagatttct ggtgcggttg
    17341 ggaactttgc caatatccca ccatttgtag aggagtatgt ctgcgataaa cttggcatcc
    17401 gtgcccaaga aatctctaca caagtccttc ctcgtgacct tcacgctgag tactttgcgg
    17461 ttcttgccag cattgcgact tcaatcgaac gtatggcgac tgagattcgt ggtctacaaa
    17521 aatctgagca acgcgaagta gaagagttct ttgctaaagg gcaaaaaggg tcttcagcaa
    17581 tgcctcacaa acgcaaccca atcggttctg aaaatatgac tggtctggcg cgtgtcattc
    17641 gtggtcacat gattacggct tatgaaaacg tcgctctctg gcacgaacgc gatatttctc
    17701 actcatcagc tgagcgtatc atcacaccag atacgaccat tttgattgac tacatgctca
    17761 accgttttgg aaatatcgtc aagaacttga cagtcttccc agaaaatatg atccgaaaca
    17821 tgaactcgac ttttggtctt atctttagcc aacgggctat gttgacattg attgaaaaag
    17881 gcatgacccg tgagcaagcc tatgacttgg tgcaaccaaa aacagcctac tcttgggaca
    17941 accaagtaga ctttaaacca cttcttgagg cagattcaga agtaacatca cgtctcacac
    18001 aagaagaaat caatgaaatc ttcaacccaa tttattacac caaacgagtg gatgatatct
    18061 ttgaacgtct tggactaggt gattaattaa aaaataaaca gcgagcttca atctcgctgt
    18121 ttatttttta tcgaaaagac ttagtcttct tttcttttag tgagtccata ggctgctagt
    18181 gtggacatga gtcctgcgac tactagtcct gcagaatcgt gagttcctgt ttcaggaagt
    18241 tttttctctg ttaccacagg agctggatct tgaggaagag ctttgctttc ctcagcagga
    18301 gcagttgatg gagctggttg gcttgggatt tctagtcttg gtttttcttc agcaatagcg
    18361 gcttgtccgt tttcatcgcc tacatgtgtt accatagttc cgacttcgac tatttgagta
    18421 acggcttcct gtgctacgac actatttaca agtgttttca cttccttacc atcggcagaa
    18481 gtgctcacag agtagaagtt gctacgatgt ccattgacgc ccttagtaat gacttgtgtt
    18541 tttcctttga gtaagagtgg attttcacga gtcactgtgg taaatggaat ttcttctttt
    18601 tggatatcca gtctaggttt tacctcagta gttggtgcaa gaccactttc atcacccttg
    18661 tgagttacag gagcgccaac ttcaaccact tggtttataa cttctttggt tacctggcta
    18721 tcaaggactg tttctgttgt ttttccattt tcagtgagta cagagatgta atgagttcgt
    18781 tcacctttga ctcctgctgt gataatattt tcctgaccag ctgggaggtt aggattttct
    18841 ttcttgataa cttcaaatgg aatttcttca gttcttgtga tgagttctgg tctggtttca
    18901 acattggcag ccacttcatt ttcatccagg cttcctgaat gagttgcagc tggtttgagg
    18961 ccttgaagag cggcttttag gttggctaca agtgtgtcaa gctcagcttg tttattacgg
    19021 ttgaggttgt aatttagagc tgttttagct gcgtcaaggg cctcaagact ttctttacta
    19081 tatccttcta agtttgtagg aattttagct aattcttcgc ggagagcatt ataattagca
    19141 cggaagtagt ctttgttgtg gtctgcaaag gcagtcatga gttcaaagat ttcctcttcc
    19201 ttgtactcag cgcttggtct atctgcccag attgaaagca tacttccgac tgttggaaga
    19261 tctacttcag gatatttggt agaagctagt tgattgaatg gaactttacc agaattttca
    19321 actgcttttg aaagagggta agcttcatct tgtttgtgat tgcctataac ataataccag
    19381 tcaccgttgg tattcaagaa tttatagcct ttgcttgcta ggtattgagg tgatgcgagg
    19441 ttatatcccc accagccttt agaccagtaa gaaatcaaga catctttgtc aaactgaaca
    19501 tcgtccttgt cttcatagta gaagccatcg ttgaaggcca ttggttgaag ccctctttct
    19561 ttggccatag ctgcgagggt gttggcatat tcggcaaatt tgccatagag ttgataccac
    19621 ttgaggtagt accagccttg ggcactagtc gcatcgttgg cgtattcgtc agtaccaaag
    19681 ttgaaaatct ttgttttacc tgcaaagaag tccatgtatt taccgatgag ggcttttaca
    19741 aagttcatcg cttcttcgtt tttcaagtcc atagttgttt ttgaaacttt atcaaagtgg
    19801 gcttgaggat ttttaatacc taatttttcc atggcaacca gcatagcatc catgtgacct
    19861 ggactgttaa tagctgggat gagaccaatg tccttagatt tagcgtattc aattagctct
    19921 gtcacttctg cctgtgttag tgcagtaccg tttggatcgt cgtagtaagc tttagttcct
    19981 tcgataatag cttttttaac gtcatcacta gcataggttt ttccgttggc agtaatggtc
    20041 atatcattga gtagaaagcg aagtccgtca tttcctagaa ggagatggac atcagaatat
    20101 ccgagctcac tggccttgtc tacgatgcgt ttgagctggt ccagagtaaa gtatttgcgt
    20161 ccagcatcga ttgagattac cttgtttttg gcaagttttt caacctcacg tttagcttct
    20221 tcttcttttt gagcttcagg cgtgagggtc aagttgttga cagtttcttg aagtttagca
    20281 atggcttgat caatcgtatc ttgttgggca cggctaaggt tgctatcgag agagcgaata
    20341 gctttttcag cttcttttac ggccgtgacg ctttctgcag tataacggtt caggtctttt
    20401 ggtacctcgt taagtgcttg ctctgcagat tcataatcag ctgcgaagta ttcagcgttg
    20461 gcatttgcaa aatgacgcat gagtttgaag aggcgtgatg gtgaataacg tgcagatgga
    20521 gtgtcagccc aagcagctac cataccaccg atgattggga tatcagctcc ttctgttttt
    20581 ggtacagaag tgattggtgt gtttttaata ccattgagcc cctgatcgag attgtaccag
    20641 ccttggccat cagcgtttcg tccaagaacg tagtaccaag catcattggt attaaggatt
    20701 tggtgacctt tttcagctag tagtttagaa gaagcgacat cgtagcctcc ccaaccacca
    20761 gtccacatag aaacgatgat gtctttgtca aaactaccaa agcttgtgtc gctattgtag
    20821 tagataccgt cgttaaaggc cattggtttg agaccgtgcg attttacaat acgagcgagg
    20881 tcattggcgt aggcaataaa tttttcatag ccttttacag ggtagccttc gtttggatag
    20941 tatttatcag cttgaagcac actccaacct ttagcatctg tcgcatcatt ggcatattca
    21001 tcaagtccga tgttgaagat ttcagtcttt ttcgcgaaat aagcagcata cttgtcgata
    21061 agggcttttg taaaagcgac agcttgttcg ttgtcaagat cgacagtacg ggctgatttc
    21121 ttcccaaaat agctaaagtt agggttttgg attcccaatt ctttcatggc attgagaatc
    21181 gcatccatgt gtccaggact atttactgtc ggaatgagac cgataccttt atctttggca
    21241 tagttaatca gatctgtcat ttgactttct gttaagtgat tgccgtttgg atcgttgtaa
    21301 taatcatttg tacctttttc aatggcgcgt ttgacatcgt cactggcata ggtcttgccg
    21361 ttagctgtga tgctcatatc gtccaacatg aaacggagtc catcatttcc gactaatagg
    21421 tgtaaatcag tgtagccata atgtttcgct ttatcgatga tttccttgag ctgttctggt
    21481 gagaaatatt tacgtccagc atcaatagaa acaattttct ttttcgctag tttttcattt
    21541 acagttgcag cacgttcctt tcctgtctct gtttccggtt tgtcagcctc tgctttcgct
    21601 tcatcttttt tagctggttt atccttgtca gtcttgtctg tatttgactc tttagaatca
    21661 acctctttcg cttcttcctt tttagggcta gcttcttctt cctttttatt agcagtttct
    21721 ttttcagcag aagttggagt taccacctct gctttatcac taggagttga actaacttcc
    21781 tcttgtggtt tttcttctgt ttttggaaga ctagctacct tatcagtagc tggagtttct
    21841 gtttctacag tttttggagc ttctggttga agctctgctt taggtgtttc ctcagtccga
    21901 ttttcggatg attgagggga atcagaaacc gtatggatgg tcggttggtt ttctgtagta
    21961 gtaggagtaa ctccatcggc tgcaacagtc tgtgcttgga aggcaaatcc aattagaaca
    22021 gaagctgctc ctacagcgta tttacgaata gaaaaacgct gttgtttttc atgtttcatt
    22081 gcaaaacctc ctgattgcat tgttatattg atagcgatta tataaatcaa cgcctttatt
    22141 ttatttctta tattaacgag agtcaagagg agatgacaaa aaactataat aagtataaaa
    22201 aaatataaaa tttaaactta agatttcaga ttggtcgaaa aaatacatat atatatctag
    22261 tataattttt ggttctattt ctataaaata ttccacaaat tatagaatct tccaaaaata
    22321 ggtaagcgct acctttttgg tgtggtataa taagcataga aaaagcccga gcgattaggc
    22381 tcaggctttc ttcttagtga tcacggtcac atgagatgaa tttaatcttg tagtaatcag
    22441 atcgtttgta agtttcactg tattctaaaa cttggccagt tgattcgagt ttggtgattt
    22501 tagtttgtag gacagtaggg aattgttcat cgactccgag gactgaagcc gcatgttctg
    22561 gagttggaaa gactatttcg ttgatttctt caaagtgttc atcattcatg tgaatgtggt
    22621 agtctaactt gaaacgatta tagatagaac tatagtattc aaggtttgga taatttgcgt
    22681 tgatatattg ttctgggatg taggatgtat ggtagatata aacgacaccg tttgattcgc
    22741 ggatacgttc aatcttgtag tagaattgat cgccgcgtag acccaatttt tccaagtaaa
    22801 caagcttgtt tccgcgttca attgaaagaa cagttacctt atcatcttta gcattgaaga
    22861 gttcaatatc tgaaaactct acaagcttgt gtttgcgtgc acgtgaaacg aaggttcctt
    22921 ttccttgttg gcggacaata tagccatctt tggcaaggtc gtttaaggcg cgaacaactg
    22981 tgatagagct gacatcgtac attgaaatga gttctgcttc agtgtaaaat ttatctccac
    23041 tgctaaactg cccagagatg attttatttt ttaattcgtc ttttatgtat tgatatttgg
    23101 gaattgccat atttttacct ctattttcct tctccataga aaattttacc ataaaagcga
    23161 aaaaaatagt agtcttttga ataaaaaatt agaataatag tttgaaaaat taagcgatat
    23221 agggattgct catattttat caatgcattc tatacaaaat tattttaggt cctatattcc
    23281 gaatttaaag agcgtttgaa atgggtctaa aaatgtttga aactaattga atgtgtgtat
    23341 aatagtaaaa atgcagtaaa tatcccgaca atttctattg acaattcaaa cagattggtt
    23401 tataattaat ataacaacaa atgaaagcgc aaactttcgc ggtcggaagg tagttttatg
    23461 acacgatttg agatacgaga tgatttctat ctcgatggaa aatcatttaa gattttatct
    23521 ggtgccattc attattttag gattcctcca gaggattggt atcattcgct ctataacttg
    23581 aaggctcttg gttttaatac ggtagagact tatgttgctt ggaatttaca cgagcctcgt
    23641 gaaggtgagt ttcattttga aggtgatctg gatttagaga aatttctcca aatagcgcag
    23701 gatttgggtc tctacgcaat tgtgcgtccg tctccattta tctgtgcgga atgggaattc
    23761 ggtggcttac cagcttggct cttgaccaag aacatgcgaa ttcgctcatc cgacccagca
    23821 tatatcgagg cagttggtcg ctactatgat cagttattgc caagactggt gcctcgtttg
    23881 ttgaacaatg gtggcaatat tctcatgatg caggttgaaa atgagtatgg ttcttacgga
    23941 gaagataagg cttacctgag agcgattcga cagctaatgg aagagtgtgg cgtaacctgt
    24001 cccctcttta catcagatgg tccatggcga gctactctga aagctggaac cttaattgaa
    24061 gaggacctct ttgtaacagg aaactttggt tctaaggcac cttacaactt ttcgcagatg
    24121 caggaattct ttgatgaaca tggtaagaaa tggccactca tgtgtatgga gttctgggat
    24181 ggttggttca atcgctggaa agaaccgatt atcacacggg atcctaagga attggcagat
    24241 gcagttcgag aggttttgga acaaggctct atcaatcttt acatgttcca cggtggtaca
    24301 aactttggtt tcatgaatgg ttgctcagct cgaggaactt tggacctgcc acaagttaca
    24361 tcttatgatt acgatgccct tctggatgaa gaaggaaatc caactgctaa atatcttgca
    24421 gtcaagaaga tgatggcaac acatttttca gagtatccgc agttggaacc actctacaaa
    24481 gagagtatgg agttggatgc tattccacta gttgaaaaag tttctttgtt tgaaacctta
    24541 gatagcttgt caagtcctgt agaaagtctc tatcctcaaa agatggagga gctgggacaa
    24601 agttatggct acctacttta tcgaacagaa acaaactggg atgcagaaga agaaagactt
    24661 cgtatcattg atggtcgaga tagggcccag ctgtatgtcg atggtcagtg ggttaaaact
    24721 caatatcaga cagagattgg ggaagatatt ttttatcaag gtaaaaagaa agggctatct
    24781 aggttagata tcttgataga aaatatgggg cgtgtcaact atgggcataa gttcttagcg
    24841 gatacgcaac gtaagggaat tcggacaggg gtctgtaagg atctgcattt cttactaaac
    24901 tggaaacact atccactccc actagacaat cctgagaaaa ttgatttttc aaaaggatgg
    24961 actcaaggac aaccagcctt ttacgcttat gactttacag tcgaagagcc aaaagatact
    25021 tacctagact tgtctgagtt tggtaaggga gttgcctttg tcaatgggca gaatctagga
    25081 cgtttttgga acgttggccc aactctctca ctttatatcc ctcatagcta tctcaaggaa
    25141 ggtgccaacc gtatcattat ctttgaaaca gaaggtcaat ataaagaaga gattcattta
    25201 actcgtaaac ctacactaaa acatataaag ggggaaaact tatgacaatt gtaggatgcc
    25261 gtattgatgg acgtttgatc cacggacaag tagccaatct ttgggctgga aaactaaatg
    25321 tttcacgcat tatggttgta gacgacgaag ttgtcaacaa cgatattgaa aagagtggtt
    25381 tgaaacttgc gacaccacca ggtgtgaaat tgagtatttt gccagttgag aaagctgcag
    25441 ccaatattct tgctggtaaa tacgatagcc aacgtctctt tatcgtggct cgtaaaccag
    25501 accgcttcct tggtttggta gaagcaggtg taccacttga aacccttaat gttgggaata
    25561 tgtctcaaac accagaaact cgttctatta cacgttctat caacgtagta gacaaggatg
    25621 tggaagactt ccacaaactg gcagaaaaag gtgttaaact tactgctcag atggttccaa
    25681 atgatccaat ttcagacttt ttgagcttat taaaatagga aaaaaatttt taggaggtca
    25741 ttgttatgat acaatggtgg caaattttac ttctcacttt gtactcagct tatcaaatct
    25801 gtgatgagtt gacgatcgtt tcatctgcag gttcccctgt atttgctggt ttcattactg
    25861 gtttaatcat gggagatgtg actactggtt tacttatcgg tggtaacttg caactgttcg
    25921 ttcttggggt tggtaccttc ggtggtgctt ctcgtatcga cgcaacttct ggtgcggttc
    25981 ttgcgacagc cttctctgtt tcacaaggaa ttgatgcacc gcttgccatt actacaatcg
    26041 ctgtaccagt agcagctctc ttgacttact tcgacgttct tggtcgtatg actactacct
    26101 tcttcgctca ccgtgtggat gctgcaatcg aacgctttga ctataaaggt attgaacgca
    26161 actacttgct tggtgcgatt ccgtgggctc tatctcgtgc ccttccagtc ttctttgccc
    26221 ttgcttttgg tggtgccttt gtacaatcag tagtagactt cgttgaagcc tacaaatggg
    26281 ttgcagatgg cttgacactt gcaggacgta tgcttccagg tcttggattt gcaatcttgc
    26341 ttcgttacct tccagttaaa cgtaaccttc actaccttgc tatgggattt ggtttgacag
    26401 ctatgttgac tgttctttac tcatatgtaa caggtcttgg tggcgctgtt gctggtatcg
    26461 taggtactct tcctgctgaa gttgctgaaa aaattggttt cgtgaacaac ttcaaaggtt
    26521 tgtctatgat tggtatttct atcgtaggta ttttccttgc agtgcttcac ttcaaaaata
    26581 gccaaaaagt agctgtagca gcaccttcta caccatcaga aagtggggaa atcgaagatg
    26641 acgaattcta attacaaact tacaaaagaa gattttaatc aaatcaacaa acgtagcttg
    26701 tttactttcc aattaggttg gaactacgaa cgtatgcaag cttctggtta cctttacatg
    26761 atcttgcctc agttgcgtaa aatgtatggt gatggaactc ctgaattgaa agaaatgatg
    26821 aaagttcata ctcaattctt caatacttca ccattcttcc ataccattat cgctggtttt
    26881 gaccttgcca tggaagaaaa agatggtgta ggttcaaaag acgctgttaa cggtatcaag
    26941 acaggtttga tgggaccatt cgctcctctt ggggatacaa tctttggttc acttgtacct
    27001 gctatcatgg ggtcagtcgc agcaactatg gctatcgctg gccaaccttg ggggatcttc
    27061 ctttggattg cagttgcagt agcgtatgac atcttccgtt ggaaacagtt ggaatttgct
    27121 tacaaagaag gggttaacct tatcaacaac atgcaaagta ccttgacagc tttgattgac
    27181 gctgcatctg tacttggtgt cttcatgatg ggtgctcttg tagcaacagt gattaacttt
    27241 gaaatttctt acaagttgcc aatcggtgaa aagatgattg atttccaaga catcttgaac
    27301 caaatcttcc cacgtttgct tccagcaatc tttactgcct ttatcttctg gttgcttggt
    27361 aagaaaggta tgaactctac taaagctatc ggtattatta tcgtacttgc tttgactctt
    27421 tctgcccttg gtcactttgc acttggaatg taattcctta tgactaaatc attaattttg
    27481 gtgagccatg gtcgcttctg tgaggagctt agaggtagca cagaaatgat tatgggccca
    27541 caagacaaca tttacacagt agctcttctt ccagaagatg gcccagaaga atttactgct
    27601 aaatttgaag ctgttattgg aggattggat gatttcctag tctttgcgga tcttctcggt
    27661 gggacacctt gtaatgtggt gagtcgcttg atcatggaag gtcgtgatat tgacctttac
    27721 gcagggatga atcttccaat ggtgattgaa tttatcaatg cgagccttac aggcgcagat
    27781 gcggactaca agagccgtgc tgcagaaagc attgtgaaag ttaatgacct gttagcgggc
    27841 ttcgatgatg acgaagatga ataatactct tcgaaaatct cttcaaacta cgtcaacgtc
    27901 gccttgccgt aggtatatgt tactgacttc gtcagtctta tccggcaacc tcaaaacggt
    27961 gttttgagct gacttcgtca gttctatctg caacctcaaa gtagtgcttt gagcagcctg
    28021 cggctagttt cctacagatt ttagttggaa ctcgattcaa ttcatgtgac aacgtgaaaa
    28081 tcgttagagc attttatata gaatatacat gggaatggag cttactccca ttcccatatt
    28141 taatagaaaa agaggaactc aatgctacat tatacaaaag aagacttgct cgaattgggt
    28201 gcagaaatca ctacgcgtga aatctaccaa caacctgatg tatggagaga agcttttgaa
    28261 ttttatcaag caaaacgtga agaaattgca gccttcctac aagaaatcgc tgataaacat
    28321 gactatatta aggttatctt gacaggtgct gggacttctg cttatgtggg agacaccttg
    28381 ctaccttact ttaaggaagt ctatgacgaa cgcaaatgga atttcaatgc tattgcgaca
    28441 acagatatcg ttgccaatcc agcaacctat ttgaaaaaag atgtggcaac tgtccttgtg
    28501 tcttttgctc gtagtgggaa ctcgcctgaa agtgtggcga ctgttgattt ggccaaatcc
    28561 ttggtggatg agctttatca agtgacgatt acttgtgcag cagatggtaa attggctctt
    28621 caagctcacg gtgatgaccg taatctcttg ctcttgcaac cagctgtctc taatgatgct
    28681 ggatttgcca tgacttctag ctttacgtct atgatgttga cagctctctt ggtctttgat
    28741 cctacagaat ttgctgttaa gtctgaacgt tttgaagttg tatctagtct tgcccgtaaa
    28801 gttttagaca aggcagaaga tgtcaaaaag ctcgttgatt tagactttaa ccgtgtcatc
    28861 tatctaggcg ctggtccttt ctttggactt gctcatgaag ctcagctcaa gattttggaa
    28921 ttaactgctg gtcaagttgc gaccatgtat gaaagcccag ttggcttccg tcacggtcca
    28981 aaatctctta tcaacgacaa tacagttgtt ttggtctttg gtacaacgac agactacact
    29041 cgtaagtacg acttggactt ggttcgtgaa gttgctggtg accagattgc tcgtcgtgtt
    29101 gtgcttttga gtgatcaagc ttttggtctt gaaaatgtca aagaagtggc ccttgattgt
    29161 ggcggtgtct tgaatgatat ttaccgtgtc ttcccttaca tcgtttatgc ccaactcttt
    29221 gccctattga cttcactcaa ggtagaaaat aaaccagata caccgtctcc tacaggtaca
    29281 gtaaaccgtg tagtacaagg tgtcataatt cacgaatatc aaaagtaaga cagtgtttat
    29341 gaattcttga caagaggatt tgtaaattat cagataaacc atagattgtc agtacgcttt
    29401 ctatggtttg tttgcttgag agaaatagta aaaggagaac agaatgaaag catacacaga
    29461 gcgtgtattt ggaaatgttg agggcgagga tgtcttggcc tatcgatttg agacagacgg
    29521 tggctaccaa cttgaggtta tgacttatgg cgcgaccatc ttgcgctatg tcgcacctga
    29581 caaggctgga aattttgcca atgttatctt gggatttgat gactttgata gttatgtagg
    29641 caatagtccc aagcatggag caagtgtagg tcctgtagcg ggtcgtattg caggtgcgac
    29701 ctttgagctc aatggtaaga cctatgacct tgaggttaat aatgctagca actgtaatca
    29761 cagtggttca actggttggg attccagctt gtttgaagtt gaagaagtaa gcgatcatgg
    29821 cttgactctc tacacagagc gtacagatgg gacaggaggg ttccctggaa atctcaagat
    29881 ttggatcagt tatcacttgg aagaaactgg tgcctatgaa atcagctaca aggtaacgac
    29941 cgatcaggat acgctggtca atccaaccaa ccacagctat ttcaacttgt ctggtgattt
    30001 cacgcagacg attgaccgtc atgtcttcca actaaacaca gagggcattt actcaatcgc
    30061 tcctgacggt gttcctgcca aaactccaga agccaaccgt gatgtggtca aacacatcta
    30121 caatggtgcc ttgttgaagg atatctttgc agaagaagat gagcaaatcc agctggcatc
    30181 aggtttggat catccatttg cccttcctgc aggccatgac aatgctggat tcctttatga
    30241 ccaaaattca ggtcgcttcc tgcttttcaa gacagaagct ccttgctttg tggtctacac
    30301 agcaaacttt gtggatgaaa gtgtcatcat aggaggtcag ccaatgctac agcacaatgg
    30361 gattgctctt gaagcgcaag ctttaccaga tgccattcac agtgacctta aaggccaagt
    30421 cattcttaaa gctggtcaaa ccttcaccag taagacacgt tatgaacttg ttgtgaaata
    30481 aaaaagctgg tcaaaaagtc tttaaaatta aaataacgca tattgtcagg tgatgaaaag
    30541 tttgataata tgcgttttat tatgaaatga tttactttat attatcctga aatggtgtta
    30601 tttttgagtt atctggcttg actttcttga tggaaattat ataatagttg caacaataat
    30661 aattacaacg aaaaaagagg accatttatg acctatgaat acaagagtca catttatttg
    30721 gcagagacag ttttaaatgt aaaggatttg gccagtcaaa cagcctttta tcagcaagtt
    30781 atcggtttag aaatcttatc tcaaactgag acagagtcca ttctaggcct tggtggaaaa
    30841 gtcttggtac agctgattca agcacaagag agcggagaag tgagggaaca ttatggtctt
    30901 taccatttgg ccattctctt gcccacacgc aaggctttgg ctgatgtctt gaaacacctg
    30961 acagatttac agattcctct tgtcggcggt gcagaccatg gttacagtga agctatttac
    31021 ttggaagatt tggagggaaa tggcattgaa ctctatcgag ataagccagt ttccacatgg
    31081 gatattcgag aagatggacg cattatcgga gtgacggagg ctcttgcggc gcaggacatt
    31141 tatgagttgg gggaaagagt agagcccttt atcctggcag aaggtacgag aatggggcat
    31201 attcatcttt cagtcaagga tagtcgaaag tccagccagt tttatcaaaa ggtgttaggg
    31261 ctagaggata aattcagtgt gcctagcgct agttggattg cggctggaga ttaccatcat
    31321 catttagcag ttaacgaatg gggaggaaaa ggtctggctt cgcgtaagca aggcttacca
    31381 ggtttagcct actatgtcat cgaagtcgca cataaaaaag aactgttaac gattgcccaa
    31441 cgagcacaag aagttgacgc accaatcaaa tggatgacat cgagccaatt ggaaatcaca
    31501 gactcagatg gcatcgtgac ccgtattcgt ttagcaaggt aaaattagga atttttaata
    31561 agttataagt attgctagtt tgctttttga acggtctttg gtaacagaac tgcgtgagct
    31621 ggatgggtga gaattttgac aaagaagctg attagagata taatgaagaa aagtcgagca
    31681 aggaaaaaga aatgacaaat tcaaagtata ttacttgttt gaaacgttca gagggccagt
    31741 tgtgtgggat tcaaaagatg attgaaggag atcgtgactg tgctgatctt gtgacgcaac
    31801 tgacagcagt gagatctagt gtagagcgcg tgattgagat gataattacc gaaaatctta
    31861 ctgaatgtat caatcagcca ctagatgatt ctgaagctca aaaggaacgc ttagaaaagg
    31921 ctatccgata cttgattaaa cggaaataaa tgaatgtttt gagacgatat gtgcaaaggt
    31981 ctattaacta ttagaatagt ttaatgtgag tcaaaagaag ttgtaaaaaa tctttaaaat
    32041 taaaaaaacg catagtatca ggtattgaaa tgtactgccc ccaaaagtta gattttttct
    32101 gtctaacttt tggggggcag tacataaaaa ccttgatagt atgcgtttta ttgtggggag
    32161 atttatactc ttcgaaaatc tcttcaaacc acgtcagctt caccttgccg tagatatggt
    32221 tactgacttc gtcagttcta tccacaacct taaaacagtg ttttgagcag cctgcggcta
    32281 acttcctagt ttgcacttta attttcattg agtattactt catcttctca tgaaattgag
    32341 tttttgccca gctcctcttg attattctac ttgaccgggc taagcattca taccaccttc
    32401 tacgttggta acggtgaggc cttgggagct gagaaattgg caggtagatg cagagcggac
    32461 tcctccttga caaataacat agtattcatg gtcaggtttg agttctttgt agccttgctc
    32521 taaggtactt aatggaagat ttttggcacc tggtgcatgt cctgcttgga attcatgtgc
    32581 ttcacggaca tcgataagtt ctagattttc attttgatat tttccataaa agtcagccat
    32641 gctgatacta gtttccatat tctactcctt ctgggttagc cattttgtat agtgaataag
    32701 cgccgtcaag gttttggacg gtaaatcctg cttgcttgag gataggctct gcgatatagc
    32761 tgcgcaaact actgtggcaa ctgacgatgt aggcttgttt ttctcctcag ttcatcagct
    32821 tcctccttga cactcggtca gattttgata caatagtaca aaattagagg aggtgggcta
    32881 tgattcagaa acatgcgatt cccattttag agtttgatga taatcctcag gcggttatca
    32941 tgcccaatca cgaggggttg gatttgcagt tgccaaagaa gtgtgtctat gcttttttag
    33001 gtgaggagat tgaccgctat gcgagggaag taggggcgaa ctgtgttggc gaattcgttt
    33061 ctgctaccaa gacctatcca gtctatgtca tcaactacaa gggtgaggag gtctgtctgg
    33121 ctcaggctcc tgttggctcc gctccagcag cccagtttat ggattggttg attggctatg
    33181 gtgtggagca gattatctct actgggacct gtggtgtcct agctgatata gaggaaaatg
    33241 cctttctagt ccctgttcgc gctttgcgag atgagggagc cagttaccac tatgtggcac
    33301 cttgtcgtta tatggaaatg cagccagagg ctattgctgc tattgaggaa gttttggaag
    33361 acagagggat tccttatgaa gaagtcatga cctggacgac agacggtttt taccgagaaa
    33421 cggctgaaaa ggtggcttat cgtaaggaag aaggctgtgc tgttgtggag atggagtgtt
    33481 ctgctcttgc tgcagtagct caattgcgtg gggttctctg gggtgaattg ttgttcacag
    33541 cagattctct agcggacttg gaccagtacg acagtcgtga ctggggctcg gaagctttta
    33601 ataaggcgct agaactgagt ttagcaagtg ttcaccacct ttagttgtac tggcaaagga
    33661 tttgttttat cataaaatgt ctagctcata cttttcaaaa atatgtttaa acgaggtcac
    33721 cttcctcttg tcctaggcat gttgaggttg ggaaaaatct ttaaaatcag aaaaacgtat
    33781 catatcaggt gatgaaaatt ttgatactat gcgttttatg ttggtaagat ttagagtgag
    33841 atgaaatgat actcttcgaa aatctcttca aaccaggtca gcttcacctt gccgtataga
    33901 tgttactgac ttcgtcagtt ctatctgcaa cctcaaaaca gtgttttgag ctgacttcgt
    33961 cagttttatc tgcaacctca aaacagtgtt ttgagctgac ttcgtcagtt ttatctgcaa
    34021 cctcaaaaca gtgttttgag ctgacttcgt cagttctatc cacaacctca aaacagtgtt
    34081 ttgagcaacc tgtgactagc tttctaatcg atgccttggt tttcattgcc tataatcaaa
    34141 aagagaaatt ttctcctgaa aagcatatag agtagctggc gttaaaagct cctgtcttgc
    34201 ttttttgacc tatagtcata tctatcaagt attgttcttg cctaagctat caataaaaag
    34261 gtggcatttt ttaggcttgg tgttagtgaa ttttgcctta tcctatctaa gtcatttcga
    34321 gctttttatg gtacaatgga aacatgttat tcaaattatc taaggaaaaa atagagctag
    34381 gcttatctcg tttatcgcca gcccgtcgta tttttttgag ttttgccttg gtcattttac
    34441 taggctctct tcttttgagc ttgccctttg tccaagttga aagctcacga gcgacttatt
    34501 ttgatcatct tttcactgct gtctctgcag tctgtgtgac aggtctctca acccttccag
    34561 tagctcacac ctataatatc tggggccaaa taatctgttt gctcttgatt cagatcggtg
    34621 gtctagggct catgaccttt attggggttt tctatatcca gagcaagcaa aagcttagtc
    34681 ttcgtagccg tgcaactatt caggatagtt ttagttatgg agaaactcga tctttgagaa
    34741 agtttgtcta ttctattttt ctcacgacct ttttggttga gagcttggga gctattttgc
    34801 ttagttttcg ccttattcct caacttggct ggggacgtgg tctttttagt tccatttttc
    34861 tagcgatctc agccttctgt aatgccggtt ttgataattt agggagcacc agtttatttg
    34921 cttttcagac cgatttactg gtcaatctgg tgattgcagg cttgattatt acaggcggcc
    34981 ttggttttat ggtctggttt gatttggctg gtcatgtagg aagaaagaaa aaaggacgtc
    35041 tgcactttca tacgaagctt gtattattat tgactatagg tttgttgtta tttggaacgg
    35101 caactactct ctttcttgag tggaacaatg ctggaacgat tggcaatctc cctgttgccg
    35161 ataaggtttt agttagcttt tttcaaacag tgacgatgcg aacagctggc ttttctacga
    35221 tagattatac tcaggctcat cctgtgactc ttttgattta tatcttacag atgtttctag
    35281 gtggggcacc tggaggaaca gctgggggac tcaagattac gacatttttt gtcctcttgg
    35341 tctttgcacg aagtgagctt ctaggcttgc ctcatgccaa tgttgcgaga cgaacgatcg
    35401 cgccgcgaac ggttcaaaaa tcctttagtg tctttattat ctttttgatg agcttcttga
    35461 taggattgat tctgctaggg ataacagcca aaggcaatcc tccctttatc cacctcatat
    35521 ttgaaaccat ttcagctctt agtacagttg gtgtaacggc aaatctgact cctgaccttg
    35581 ggaaattggc tctcagtgtt atcatgccac ttatgtttat gggacgaatt ggtcccttga
    35641 ccttgtttgt tagcttggca gattaccatc cagaaaagaa agatatgatt cactatatga
    35701 aagcagatat tagtattggt taagaaagga aagagcatgt cagatcgtac gattggaatt
    35761 ttgggcttgg gaatttttgg gagcagtgtc ctagctgtcc tagccaagca ggatatgaat
    35821 attatcgcta ttgatgacca cgcagagcgc atcaatcagt ttgagccagt tttggcgcgt
    35881 ggagtgattg gtgacatcac agatgaagaa ttattgagat cagcagggat tgatacctgc
    35941 gataccgttg tagtcgcgac aggtgaaaat ctggagtcga gtgtgcttgc ggttatgcac
    36001 tgtaagagtt tgggggtacc gactgttatt gctaaggtca aaagtcagac cgctaagaaa
    36061 gtgctagaaa agattggagc tgactcggtt atctcgccag agtatgaaat ggggcagtct
    36121 ctagcacaga ccattctttt ccataatagt gttgatgtct ttcagttgga taaaaatgtg
    36181 tctatcgtgg agatgaaaat tcctcagtct tgggcaggtc aaagtctgag taaattagac
    36241 ctccgtggca aatacaatct gaatattttg ggtttccgag agcaggaaaa ttccccattg
    36301 gatgttgaat ttggaccaga tgacctcttg aaagcagata cctatatttt ggcagtcatc
    36361 aacaaccagt atttggatac cctagtagca ttgaattcgt aaagagggat gacccctctt
    36421 ttttgatgct taagatggca aatagagaca gaagcccctt gtcttctagt aaaagttctt
    36481 caaaggctgg actttatggt aaaatagaag gaagtgacaa gagagagtaa tactcaatga
    36541 aaatcaaaga tcaaactagg aaactagctg cgggctgctc aaaacactgt tttgaggttg
    36601 tggatagaac tgacgaagtc agctcaaaac actgttttga ggttgcagat agaactgacg
    36661 aagtcagtaa catctatacg gcaaggcgac gttgacgcgg tttgaagaga ttttcgaaga
    36721 gtataagaaa aaatcagtcc cctaaaggag cagattatga agttattgtc tatcgccatt
    36781 tctagctata atgcagcagc ctatcttcat tactgtgtgg agtcgctagt gattggtggt
    36841 gagcaagttg ggattttgat tatcaatgac gggtctcagg atcagactca ggaaatcgct
    36901 gagtgtttag ctagcaagta tcctaatatc gttagagcca tctatcagga aaataaaggc
    36961 catggcggtg cggtcaatcg tggcttggca gaggcttctg ggcgctattt taaagtagtt
    37021 gacagtgatg actgggtgga tcctcgtgcc tacttgaaaa ttcttgaaac cttgcaggaa
    37081 tttgagagca agggtcaaga ggtggatgtc tttgtgacca attttgtcta tgaaaaggaa
    37141 ggtcagtctt gtaagaagag tatgagttac gattcagtct tgcctgttcg gcagattttt
    37201 ggctgggacc aggtcggaaa tttctccaaa ggccagtata tcatgatgca ctcgctgatt
    37261 tatcggacag atttgttgcg tgctagccag ttctaattgc ctgaacatac tttttatgtc
    37321 gataatctct ttgtctttac gccccttcag caggtcaaga ccatgtacta tctgcctgtc
    37381 gatttctatc gttatttgat tgggcgtgag gaccagtctg tcaatgagca agtgatgatt
    37441 aagtgcattg accagcaact caaggtcaat cgactcttgg tagaccaact ttatttgtcc
    37501 caagtgagtc atcccaaaat gcgagaatat ctgctgaatc atattgaaat cacgacggtg
    37561 atttccagta ccctgctcaa ccgatctgga acagcggagc atctggcaaa aaaacgccaa
    37621 ttgtggacct atattcagca gaaaaatcca gaagtctttc aggctattcg taagaccatg
    37681 ttgagccgtt tgaccaaaca ttctgtcttg ccagatcgca aactgtccaa tgtcgtctat
    37741 caaatcacca aatctgttta tggatttaat taatataagt gttttataag agggatttaa
    37801 gaaaaatttt aactttttct tagtcctttt taatttcagg agattatact agagtcatca
    37861 aataaagaaa gactctaagg agaatcctat gaaattcaat ccaaatcaaa gatatactcg
    37921 ttggtctatt cgccgtctca gtgtcggtgt tgcctcagtt gttgtggcta gtggcttctt
    37981 tgtcctagtt ggtcagccaa gttctgtacg tgccgatgtg gtcaatccga ccccaggtca
    38041 agtcttacct gaagagacat cgggaacgaa agagggtgac ttatcagaaa aaccaggaga
    38101 caccgttctc actcaagcga aacctgaggg cgttactgga aatacgaatt cacttccgac
    38161 acctacagaa agaactgaag tgagcgagga aacaaactct tctagtctgg atacactttt
    38221 tgaaaaagat gaagaagctc aagaaaatcc agagctaaca gatgccttaa aagaaactgt
    38281 agatacagct gatgtggatg ggacacaagc aagtccagca gaaactactc ctgaacaagt
    38341 aaaaggtgga gtgaaagaaa atacaaaaga cagcatcgat gttcctgctg cttatcttga
    38401 aaaagctgaa gggaaaggtc ctttcactgc tggtgtaaac caagtaattc cttatgaact
    38461 attcgctggt gatggtatgt taactcgtct attactaaaa gcttcggata atgctccttg
    38521 gtctgacaat ggtactgcta aaaatcctgc tttacctcct cttgaaggat taacaaaagg
    38581 gaaatacttc tatgaagtag acttaaatgg caatactgtt ggtaaacaag gtcaagcttt
    38641 aattgatcaa cttcgcgcta atggtactca aacttataaa gctactgtta aagtttacgg
    38701 aaataaagac ggtaaagctg acttgactaa tctagttgct actaaaaatg tagacatcaa
    38761 catcaatgga ttagttgcta aagaaactgt cgaaaaagct gttaaagata acgttaaaga
    38821 cagtatcgat gttccagcag cctacctaga aaa
//
LOCUS       DAVLBE010000016        36306 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.016, whole genome shotgun sequence.
ACCESSION   DAVLBE010000016 DAVLBE010000000
VERSION     DAVLBE010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 36306)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36306)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36306
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.016"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            <1..1563
                     /locus_tag="VXB91_000853"
     CDS             <1..1563
                     /locus_tag="VXB91_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HEV0470332.1"
                     /translation="DLYEIIKEGIRFNFENPIFDMKRSTNEFIGRSAMVTKLLCIYTE
                     GDPFFGVNINSQKEFWNHFVSQTNQGGPYLQNHKIIELVSKTYPELEPSKLGTMLFEY
                     SKLFMENKEDNSTMDSSNNFRHQLTQSLLKSPNLILRGAPGTGKTYLAKEIAKELTDG
                     NEDQIGFVQFHPSYDYTDFVEGLRPVSNGDGAIEFRLQDGIFKDFCQKAKETQLIGGQ
                     DNFDEAWDSYLEYINVAEEKEYITKTSYLSINSRQNLSVNYDSGVSGWSLPSKYVYEL
                     YKDKNYNKQEYYKSGGKTVLETLRKRFGLKDYVSPTEIDTDKKFVFIIDEINRGEISK
                     IFGELFFSIDPGYRGEKGSVSTQYANLHETDEKFYIPENVYIIGTMNDIDRSVDTFDF
                     AMRRRFRFVEVTAEGQVGMLDKELNIHAEEAKIRLRNLNAAIENVQELNSHYHIGPSY
                     FLKLKDVDFDYELLWSDYIKPLLEDYLRGSYDEVETLETLKKAFELTNNEQKDQAVAD
                     DNEGDENDDADY"
     gene            1550..2866
                     /locus_tag="VXB91_000854"
     CDS             1550..2866
                     /locus_tag="VXB91_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HEV0470333.1"
                     /translation="MRITDNQHKIIKEKFVEEYPKLSNLLLDRTLESLSQDERIFIFP
                     NDLTHTPDLDKDQKIFETVNQKIKTGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKVLYINLTSLDVALSREERLYQLLMYLFPKYLQAAIRKGLYKEYHRFFHNDSNVKGV
                     IDVRSHLKKNLPFTGNIAYATREFTYDNPLMQLVRHTIEYIKNQKSIGQGVLDNLSTS
                     RENVSEIVRVTPSYKLADRAKITRRNQSKPIRHAYFHEYRNLQELCLMILNQEKHGLG
                     YQDQKIYGILFDVAWLWEEYVYTLLPKGFVHPRNKDKTDGISVFSVGKRKVYPDFYDR
                     ERKIVLDAKYKKLELTEKGINREDLFQLISYSYILKAEKAGLIFPSMEQSVNSEIGKV
                     AGYGAQLKKWSIRIPQNASSYSAFCKMMENSEENFKAIIDEEVGRK"
     gene            3042..4028
                     /locus_tag="VXB91_000855"
     CDS             3042..4028
                     /locus_tag="VXB91_000855"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HEV0470334.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKRMHNQGLIASISVGVKDYEY
                     DFVRQLKTDAPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCVKAARKPIIADGGIRTHGDIT
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            4092..4163
                     /locus_tag="VXB91_000856"
     tRNA            4092..4163
                     /locus_tag="VXB91_000856"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4125..4127,aa:Arg,seq:ccg)
     gene            4346..5044
                     /locus_tag="VXB91_000857"
     CDS             4346..5044
                     /locus_tag="VXB91_000857"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HEV0470335.1"
                     /translation="MKELQTVLKNHFAIEFTDKKLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFDQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVMIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            5035..8574
                     /gene="smc"
                     /locus_tag="VXB91_000858"
     CDS             5035..8574
                     /gene="smc"
                     /locus_tag="VXB91_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HEV0470336.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENARKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELAQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLATLEDKRSS
                     LSQEKSDKESSLALLEENLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSHQLSQKQADQLEKLKEQLATAKEKAGQQKAELETAKEQVQK
                     LLADYQVCAKEQEEQKTSYQAQQSQLFDRLDSLKNKQARAQSLENILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDMHYQTALEIALGASSQHIIVEDENAATKAIDLLKR
                     NRSGRATFLPLTTIKARTISSQNQDTIAASPGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDTVEHARAAARQVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIFIKPELEQLQK
                     EIAEEEASLRSDEVSLKNLQDELARLTERLEAIKSQGEQARIQEQGLSLAYQQTSQQV
                     EELETLWKLQEEELNRLSEGEWQADKEKCQERLTTITSEKNNLEAEIEEIKSNKNAIQ
                     ERYQNLQEELAQARLLKTELQGQKRYEVADIERLGKELDNLDIEQEEIQRLLQEKVDN
                     LEKVDTDLLSQQADEAKTQKTNLQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRHLQNQLTDQYQISYTEALEKAHELENLNLAEQEVQDLEK
                     AIRSLGPVNLDAIEQYEEVHNRLDFLNSQRDDILSAKNLLLETITEMNDEVKERFKST
                     FEAIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            8571..9365
                     /locus_tag="VXB91_000859"
     CDS             8571..9365
                     /locus_tag="VXB91_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV0470337.1"
                     /translation="MTIKLVATDMDGTFLDGNGRFDMDRLKSLLASYKEKGIYFAVAS
                     GRGFLSLEKLFAGVRDDIIFIAENGSLVEYQGQDLYEATMSRDFYLATFEKLKTSPYV
                     DINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEAGEAWVNDNVPGVKAMTTGFESIDIVLDYVDKGVAIVELAKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKERSVIAYMEGL"
     gene            9365..10183
                     /locus_tag="VXB91_000860"
     CDS             9365..10183
                     /locus_tag="VXB91_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV0470338.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKETLKAARDRGIKVVLTT
                     GRPLKAMDFFLHELGTDGQEDEYTITFNGGLVQKNTGEILDKTVFSYDDVARLYEETE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSSQMTYNKCVTAFAQE
                     PLDAAIQKISPELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGIDQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVPEVKAAANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            10187..11464
                     /gene="ftsY"
                     /locus_tag="VXB91_000861"
     CDS             10187..11464
                     /gene="ftsY"
                     /locus_tag="VXB91_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HEV0470339.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEVEEVS
                     QEEAEVEIVEQAVFQEEEIQDTVEESLDLEPVIEVSQKEVKEFPHSEEGNTEFLETVE
                     ENNSEILEAERPQTEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEELEEL
                     LIMSDVGVQVASNLTEELRYEAKLENAKKPDALRRVIIEKLVELYEKDGSYDESIHFQ
                     DNLTVMLFVGVNGVGKTTSIGKLAHRYKRAGKKVMLVAADTFRAGAVAQLAEWGRRVD
                     VPVVTGPEKADPASVVFDGMERAVAEGIDILMIDTAGRLQNKDNLMAELEKIGRIIKR
                     VVPEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAIREEL
                     NIPVKLIGFGEKIDDIGEFNSENFMKGLLEGLI"
     gene            complement(11510..12997)
                     /locus_tag="VXB91_000862"
     CDS             complement(11510..12997)
                     /locus_tag="VXB91_000862"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HEV0470340.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYKSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATASKLN
                     DELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPASFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRSVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVGASWKLIDRIEELWD
                     ENGAPLHDYKAGSMGPQASFDLLEKFGAKWTWQPDIAYRQDGRLE"
     gene            complement(13146..13886)
                     /locus_tag="VXB91_000863"
     CDS             complement(13146..13886)
                     /locus_tag="VXB91_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV0470341.1"
                     /translation="MAKLKIDVNDLHKHYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEELGMELLEKVGLADKANANPDSLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            complement(13886..16051)
                     /locus_tag="VXB91_000864"
     CDS             complement(13886..16051)
                     /locus_tag="VXB91_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEV0470342.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALAEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
     gene            16224..17177
                     /locus_tag="VXB91_000865"
     CDS             16224..17177
                     /locus_tag="VXB91_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0470343.1"
                     /translation="MKNKRIFKDFQASKMSLNIYTSPLLAFVFVFIGEFVAFTLYGIG
                     LLALIGLARNFGEAGQNLASYLQTLQQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENFLSNLLKGFSLGLALFLLTLLGLVVLGQYRLESIHLNPYSLAF
                     VVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLAILISSLFFTLLHMGNSSLTPLS
                     LVNLFLFGVAMALYLLKTDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQ
                     GNQDWLSGGSFGIEGSIMTSLVLLLLIVYLANKLKKENERM"
     gene            17254..19242
                     /gene="uvrB"
                     /locus_tag="VXB91_000866"
     CDS             17254..19242
                     /gene="uvrB"
                     /locus_tag="VXB91_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HEV0470344.1"
                     /translation="MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAIAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTIGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD"
     gene            19252..19815
                     /locus_tag="VXB91_000867"
     CDS             19252..19815
                     /locus_tag="VXB91_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0470345.1"
                     /translation="MIYLRKLKREDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKQTRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLGLTTWSGNLGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKINDGYYQINGNS"
     gene            19781..20269
                     /locus_tag="VXB91_000868"
     CDS             19781..20269
                     /locus_tag="VXB91_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0470346.1"
                     /translation="MTVIIKSMETPKEIEGKSLVHWQMWREAYDDLLPAEFQETMTLE
                     RCRLFSQKYPENTLIAIGDLKVVGFISYGNFRDETMQAGEIIALYVLKDYYGKGIAQK
                     LMKAALTALNHFSEIFLWVLKDNKRAIAFYQKMGFTFDGQEKILELGKPIKEKRMVFY
                     SK"
     gene            20343..20810
                     /locus_tag="VXB91_000869"
     CDS             20343..20810
                     /locus_tag="VXB91_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEV0470347.1"
                     /translation="MSRSQLTILTNICLIEDLETQRVVMQYRAPENNRWSGYAFPGGH
                     VENDEAFAESVIREIYEETGLTIQNPQLVGIKNWPLDTGGRYIVICYKATEFSGSLRS
                     SDEGEVSWVQKDQIPNLDLAYDMLPLMEMMEAPDKSEFFYPRRTEDDWEKKIF"
     gene            complement(20807..21322)
                     /locus_tag="VXB91_000870"
     CDS             complement(20807..21322)
                     /locus_tag="VXB91_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HEV0470348.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHEVEEIGQELLAIVDNGGHVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFRPLSELTDGIHYHLVEAETQQDLHYIEE
                     ALDQLGYLVKD"
     gene            complement(21334..21861)
                     /locus_tag="VXB91_000871"
     CDS             complement(21334..21861)
                     /locus_tag="VXB91_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV0470349.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHISFGALGALYLQKFPDTL
                     DKPKSSWVFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
     gene            complement(22139..22702)
                     /locus_tag="VXB91_000872"
     CDS             complement(22139..22702)
                     /locus_tag="VXB91_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV0470350.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILTLAIVPRLQTLKK"
     gene            complement(22686..23237)
                     /gene="coaC"
                     /locus_tag="VXB91_000873"
     CDS             complement(22686..23237)
                     /gene="coaC"
                     /locus_tag="VXB91_000873"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HEV0470351.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLTLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLIAPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETIDEKTL"
     gene            complement(23249..23938)
                     /gene="coaB"
                     /locus_tag="VXB91_000874"
     CDS             complement(23249..23938)
                     /gene="coaB"
                     /locus_tag="VXB91_000874"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HEV0470352.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLSAGHEVC
                     LITTKRALKPEPHPNLSIREITNTKDLLIEMQERVQDYQVLIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISADQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            24168..25838
                     /locus_tag="VXB91_000875"
     CDS             24168..25838
                     /locus_tag="VXB91_000875"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEV0470353.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELEIDQRR
                     ILWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKRR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAVL
                     KELCASIDVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNALSVQEKIEK
                     IVTEIYRGSKVNFEKKAQTQIAQIVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
     gene            26166..27341
                     /gene="mutY"
                     /locus_tag="VXB91_000876"
     CDS             26166..27341
                     /gene="mutY"
                     /locus_tag="VXB91_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HEV0470354.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATAPEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     FIEVDNFSQEEQFDLFHQVAEESVNFGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYAQANLDSSQD"
     gene            27396..28100
                     /locus_tag="VXB91_000877"
     CDS             27396..28100
                     /locus_tag="VXB91_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0470355.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            28093..29442
                     /gene="vicK"
                     /locus_tag="VXB91_000878"
     CDS             28093..29442
                     /gene="vicK"
                     /locus_tag="VXB91_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HEV0470356.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     HLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            29444..30253
                     /locus_tag="VXB91_000879"
     CDS             29444..30253
                     /locus_tag="VXB91_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEV0470357.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
     gene            30344..30586
                     /locus_tag="VXB91_000880"
     CDS             30344..30586
                     /locus_tag="VXB91_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HEV0470358.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVADLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            30588..30842
                     /locus_tag="VXB91_000881"
     CDS             30588..30842
                     /locus_tag="VXB91_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEV0470359.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQTNVLEGPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHRRDIY"
     gene            30889..31584
                     /locus_tag="VXB91_000882"
     CDS             30889..31584
                     /locus_tag="VXB91_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium channel family protein"
                     /protein_id="HEV0470360.1"
                     /translation="MKKKWLFADYYDTTIILLALISVILVLLGFAEMTDLDNPPYSII
                     DLVIWGVFVIDYSWRFFITKRKWRFILENIFDLLTILPLNAIFTVFRLGRIFRLARLT
                     KLLKLTRLLRIIGLTGKLERKISRFLRTNGLIYILYVNIFIVLVGSSILSVVEEKSFS
                     DSLWWALVTVTTVGYGDIVPVSLFGKWLAVLLMLVGIGTIGMLTSALTNFFVKDNPDE
                     QIKLDKLKDELSS"
     gene            complement(31933..32919)
                     /locus_tag="VXB91_000883"
     CDS             complement(31933..32919)
                     /locus_tag="VXB91_000883"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HEV0470361.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGQYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            33113..35581
                     /gene="gyrA"
                     /locus_tag="VXB91_000884"
     CDS             33113..35581
                     /gene="gyrA"
                     /locus_tag="VXB91_000884"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001152996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HEV0470362.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIVLRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMVGQILSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLTEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEA"
     gene            35581..>36306
                     /gene="srtA"
                     /locus_tag="VXB91_000885"
     CDS             35581..>36306
                     /gene="srtA"
                     /locus_tag="VXB91_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HEV0470363.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKETKDYSQTSDEILTAFNQP"
BASE COUNT        11153 a         6417 c         8079 g        10657 t
ORIGIN      
        1 gatttgtatg aaattatcaa agaaggtatt cgttttaact ttgaaaatcc tatttttgat
       61 atgaaaagat caacaaatga atttattggt cgttctgcta tggtgacaaa attactttgt
      121 atctatactg agggagatcc tttctttggt gtaaatatta atagtcagaa agaattttgg
      181 aaccactttg tttctcagac aaatcaaggt ggaccttatc tgcaaaatca taaaataatt
      241 gaactagtgt ccaaaactta tcctgagttg gagccatcga aattaggaac tatgcttttt
      301 gagtattcta agctttttat ggaaaataag gaagacaata gtacaatgga ttcatcaaac
      361 aattttcgtc atcaattaac tcaatctcta ttaaagtctc caaacctcat cctccgtggt
      421 gctcctggca caggaaagac ttatcttgct aaagaaattg ccaaagaatt aacggatggc
      481 aacgaagacc aaatcggatt tgtacaattt cacccatcct atgattatac ggattttgta
      541 gaaggtttaa gaccagtatc aaatggggat ggagctattg agtttaggct acaggacggt
      601 atttttaaag atttttgtca gaaagcaaaa gaaacccaat tgattggagg acaagataat
      661 tttgatgagg cttgggattc ttacttagaa tatataaatg ttgctgaaga aaaagaatat
      721 ataacaaaaa catcttactt atctattaat agtagacaaa atttgtcagt aaattatgat
      781 agtggtgttt caggatggtc actacctagc aaatatgttt acgagttgta taaagataaa
      841 aattataata agcaagaata ctacaaaagt ggtggaaaaa ctgtcctaga aacattgaga
      901 aagagatttg gtttgaaaga ctatgtttcc ccaacagaaa ttgatactga taagaaattc
      961 gtcttcatca tcgatgaaat caatcgtggg gagatttcta agatttttgg cgaactcttt
     1021 ttctctatcg accctggcta tcgtggtgaa aaaggaagtg tttctaccca atatgcaaat
     1081 ctacacgaaa ctgatgaaaa gttctatatc cccgaaaatg tttacatcat cggaactatg
     1141 aatgatattg atcgttcagt ggataccttt gattttgcta tgcgtcgtcg ttttcgtttt
     1201 gttgaagtta ctgccgaggg tcaagttggc atgttggata aagagctgaa tatccatgca
     1261 gaagaagcaa aaattcgtct aagaaacttg aacgctgcta tcgaaaatgt tcaggaatta
     1321 aacagtcatt atcatattgg accaagttat tttcttaagt tgaaggatgt agattttgac
     1381 tatgaattac tctggtctga ttatattaag cctctcctag aagactactt gcgaggttct
     1441 tatgatgagg ttgaaacttt ggaaactttg aaaaaagcat ttgaactgac aaataatgag
     1501 caaaaagatc aggcagtagc tgatgacaat gaaggtgatg aaaacgatga tgcggattac
     1561 tgataatcaa cacaagatta ttaaagaaaa atttgttgaa gaatatccta aactaagcaa
     1621 tcttctttta gacagaacct tggaaagtct atcccaagat gaacgtattt tcatttttcc
     1681 aaatgatttg actcatactc ctgatttgga taaggaccaa aagatttttg aaacagtcaa
     1741 tcagaaaatc aagacaggga acgtgattgg ttttcttgga tatggtcagg aaagattaac
     1801 gatttcctca cgattttctg atgagagtaa tgaccatttt ttgcattatc tcttaaacaa
     1861 ggttctttat atcaatctca ctagtttaga tgttgctttg tctcgtgaag agaggcttta
     1921 tcaacttttg atgtatctct tccccaagta tctacaagct gctattcgaa aaggtcttta
     1981 taaggaatat catcgatttt ttcataacga cagtaatgtt aagggagtga ttgatgtaag
     2041 aagccatctc aagaaaaatc ttcctttcac gggaaatatt gcctacgcaa cgagagagtt
     2101 cacctatgat aatcccctca tgcagttggt ccgtcacact attgaataca ttaagaatca
     2161 gaaaagcatt ggtcaagggg tactagataa tctctcaact agtcgtgaaa acgtatctga
     2221 aatcgtgcgt gtaacgccct cttataaact agctgatcgt gctaagatta ctcggagaaa
     2281 tcaatctaaa cctatacgtc atgcatactt tcacgagtac agaaacttac aagaactttg
     2341 tctgatgatc ctaaaccaag aaaagcacgg tttagggtat caagatcaaa aaatctatgg
     2401 tattctcttt gatgttgcct ggctttggga agagtatgtt tacaccttgt tgccaaaagg
     2461 ttttgtacat cccagaaata aggataagac ggatggaatt tcagtatttt ctgttgggaa
     2521 acgaaaagta tatccagatt tttatgacag agaacgaaag attgttctag atgcaaaata
     2581 taaaaaactg gaattgactg aaaaaggaat caaccgtgag gacttattcc agctgatttc
     2641 ctattcttat attttaaaag ctgagaaggc tggactgatt tttcctagta tggagcagtc
     2701 agtaaatagt gaaataggaa aagtagctgg ctatggagct caattgaaga agtggtctat
     2761 tcgaatccct cagaatgcct catcctatag tgcattttgt aaaatgatgg aaaattcaga
     2821 agaaaatttt aaagcgatta ttgatgaaga agtggggaga aaataatttc ccctctttct
     2881 tttattttta acacaagtaa aacccgaacg atatatttta attcataaaa aaaaattgac
     2941 aaaaactgta ctttggttta taataaatta aggaaacgtc ggaaaaggcg tagtgatgcg
     3001 agagcatagg taggtcatta caaaagaaac gagacatcga tatgttaaat gaatttccaa
     3061 tttttgatta cgaagatatt caattgattc caaataaatg tgtcattaaa agccgtgcag
     3121 aagcggatac aagtgtcact ttaggaaatc acacctttaa actacctgtt gtgccagcga
     3181 atatgcagac gattttggat gaaaatgtag cagagcaact ggctaaaggt ggttacttct
     3241 acattatgca ccgttttgat gaggcaggac gcattccttt tattaaacga atgcacaatc
     3301 aagggctcat tgcttccata tctgtcggtg ttaaggacta tgagtatgat ttcgttagac
     3361 agctcaagac tgatgctcct gagtatatca ctattgatat tgctcatggt catgcggata
     3421 gcgtgatttc tatgattcaa cacatcaaga aagaattgcc agataccttt gtcattgctg
     3481 gaaatgtggg aacaccagaa gctgtgcgtg aattggaaaa tgctggtgcg gatgctacta
     3541 aggtcggaat cggtcctggt aaggtttgta tcaccaaggt taagactggt tttggtacag
     3601 gtggttggca gttggctgct ctacgctggt gtgtcaaggc tgcgcgtaaa ccgattatcg
     3661 ctgatggagg aattcgtact cacggtgata ttaccaagtc tatccgcttc ggtgctagca
     3721 tgatcatgat tggttccctc tttgcaggac atattgaaag tccagggaaa acgattgaag
     3781 tcgatggtga acagttcaaa gaatattatg gttcagcctc acaatatcaa aaaggtgctt
     3841 acaaaaatgt ggaaggcaaa cgtatcttgc ttcctgctaa aggtcatctg caagacactt
     3901 taactgagat ggaacaagac cttcaaagtg ctatttctta tgcaggtgga cgtcaggttg
     3961 ctgaccttaa acacgttgat tatgtgatcg tgaaaaactc catctggaat ggggatgctt
     4021 cccactaaga cggggtcttt gactaaaaaa cttgttatta gagcaaattt ctgttataat
     4081 aaaacaagtt tccaccctta gtgtaatgga tatcacgtaa gattccggtt cttgagatgg
     4141 gggttcgatt ccctcagggt ggatgtaaac attctaaaaa gcctttaata gggctttttt
     4201 ctttacactg ctctaaattt accgctaaaa ctgagaatct ctgtctaaag aatttccaaa
     4261 tgctttccag tcccgtttta gagtgactca gggggctttt tttgatataa taaaaaggac
     4321 tgttatcagt tagaaagagg ttggtatgaa agaattacaa actgtactaa agaaccattt
     4381 tgcaatcgaa tttacagaca aaaagttact ggaaactgcc tttactcata cgagttatgc
     4441 caatgagcac cgcctcttaa aaatttcaca taatgaacgc ttggaatttt taggagacgc
     4501 tgttctacag ttattgattt cagaatatct gtataaaaaa tatcctaaaa agcctgaagg
     4561 tgacctatca aaactccgtg ctatgattgt ccgtgaggag agtttagctg gttttgcgcg
     4621 tgattgccag tttgaccagt ttatcaagtt gggtaaaggg gaagaaaaat ctggtggtcg
     4681 caatcgtgac accattcttg gtgatgcctt tgaagccttt cttggtgccc ttcttttgga
     4741 taaggatgtg gccaaggtca aggaatttat ctatcaagtc atgattccta aggttgaagc
     4801 aggcgaattt gagatgatta cagactataa aacccatctc caagagttac ttcaggtcaa
     4861 tggtgatgtg gctattcgtt atcaggtgat ttctgaaaca gggcctgctc acgataaggt
     4921 ctttgatgta gaagttcttg ttgaaggtaa gagtatcggt caaggccaag gtcgttctaa
     4981 gaaattagca gagcaggaag ctgccaaaaa tgccgttgag aaggggctgg attcatgtat
     5041 ttaaaggaaa tcgaaattca ggggttcaag tcttttgctg ataagaccaa ggtcgttttt
     5101 gaccaaggtg tgacggcagt tgttggaccc aatggatctg gaaagtccaa tattacagaa
     5161 agtctgcgtt gggctttggg ggagtctagt gtcaagagtc tccgtggggg caagatgccg
     5221 gatgtcatct ttgctggaac agaaagtcgc aaaccgctca attatgcttc tgtagttgtg
     5281 actctggata atcatgacgg atttatcaag gatgcaggtc aagaaatcag ggtggaacgc
     5341 catatctatc gtagtggaga tagcgaatac aagattgacg gcaagaaagt ccgtctgcgt
     5401 gatattcatg acctcttctt ggatactgga ttgggacgag attccttctc tattatttcc
     5461 caagggaagg ttgaggagat ttttaattcc aagcctgagg aacgacgagc tatttttgaa
     5521 gaagctgctg gagttttaaa atacaagact cgcagaaaag aaaccgagag taaactgcag
     5581 caaactcagg ataatctgga ccgcttagag gacattatct acgagttgga taatcaaatc
     5641 aagcctcttg agaagcaagc tgagaatgcc cgtaagtttt tagacttgga aggacaacgt
     5701 aaggctattt atttagacgt tctggttgct caaatcaagg aaaataaggc tgaactagag
     5761 tcgacagaag aagagttggc tcaggttcaa gaactcttga tgagttatta ccaaaagcgt
     5821 gaaaaattag aagaagaaaa tcaaactctt aaaaagcaac gccaagattt acaggctgaa
     5881 atggccaaag accaaggcag tttgatggat ttgaccagtc tgattagtga cttagagaga
     5941 aaattagccc tatcgaaact ggaatctgag caagtagccc tcaatcaaca ggaagcacaa
     6001 gcccgtttgg ctactttgga ggataagaga agttcactca gccaagaaaa atctgataaa
     6061 gaaagctctt tagccctctt ggaagaaaat ctagtccaaa ataatcaaaa actcaatcga
     6121 ttagaggctg aattgctagc tttttcagat gatcctgatc agatgattga gctcttacgt
     6181 gaacgctttg tggccctttt acaagaagaa gcagatgtct caaaccaact gacccgtatt
     6241 gagaatgagt tggaaaatag tcatcagctt tctcaaaaac aagcagatca actagaaaag
     6301 ctgaaagaac agttggctac agctaaagag aaggctggtc agcaaaaggc tgagcttgaa
     6361 actgccaagg agcaggttca gaaattattg gccgactatc aagtctgtgc taaggagcaa
     6421 gaggagcaga aaacttccta tcaagctcaa caaagtcaac tctttgaccg tctggatagt
     6481 ctcaaaaaca agcaggctag agcgcaaagt ttggaaaata tcctgagaaa tcatagtaac
     6541 ttttatgcag gtgttaagag tgttctccaa gagaaagatc gtctaggtgg gattattgga
     6601 gcagttagtg agcacctgac ctttgatatg cattatcaaa ctgccctaga aattgcgctt
     6661 ggagcgagta gtcagcacat tattgtagaa gatgagaatg cggcaaccaa agccattgat
     6721 ttactcaaac gaaacagatc tggtcgtgca accttccttc ctttgaccac tatcaaggct
     6781 cgtacgattt ctagtcagaa ccaagatact attgctgcaa gtccaggatt tctgggcatg
     6841 gcagatgagc tggttacttt cgatactaga ctggaagcca ttttcaagaa tttgctagct
     6901 acaacggcca tttttgatac cgtggagcat gcgcgtgcag cagcgcgcca ggttcgttat
     6961 caggttcgta tggtgacatt ggacggaaca gagctgcgca caggtggttc ttatgcaggt
     7021 ggagctaatc gccagaataa cagtattttc atcaagccag aactggagca attacaaaaa
     7081 gaaattgctg aagaagaagc aagtttgcgt tcagatgaag tgagtttgaa gaacttgcaa
     7141 gatgagctag ctagattgac agaaagatta gaagccatca aatctcaggg agagcaggct
     7201 cgtattcagg agcaaggctt gtccctcgcc tatcagcaga ccagtcagca agttgaagag
     7261 ctagaaactc tttggaaact ccaagaagag gaattaaatc gtctttctga gggagaatgg
     7321 caagcggata aggaaaaatg ccaagagcgc cttactacaa tcactagtga aaagaataat
     7381 ctggaagctg agattgaaga gattaagtct aataaaaacg ccatccaaga acgttatcaa
     7441 aacttgcagg aagagctagc tcaagctcgt ctacttaaga cagaactgca agggcaaaaa
     7501 cgttatgaag ttgctgatat tgaacgctta ggtaaggaac tagataatct tgatattgag
     7561 caagaagaaa ttcagcgcct tcttcaagaa aaggttgaca atcttgagaa agttgatacg
     7621 gatttgctca gtcaacaggc tgatgaagcc aaaactcaaa aaacaaatct ccaacaaggt
     7681 ttgattcgca agcagtttga gttggatgat attgagggtc aactggatga tattgctagt
     7741 catttggatc aggctcgcca gcagaatgaa gagtggattc gcaagcaaac tcgtgctgaa
     7801 gccaagaaag aaaaggttag cgagcgcttg cgccatctac aaaatcaatt aacagaccag
     7861 taccagatta gctatactga agcactagaa aaagcgcatg agttggaaaa tctcaatctg
     7921 gcagagcaag aggtgcagga tttagagaag gctattcgct cactgggacc tgtcaattta
     7981 gacgctattg aacagtacga agaagttcac aaccgtctgg atttcctaaa tagccaacgt
     8041 gatgatattt tgtctgcgaa aaacctgctt cttgaaacaa tcacagagat gaatgatgag
     8101 gtcaaggaac gctttaaatc aacctttgag gccattcgtg agtcctttaa agtgaccttc
     8161 aagcagatgt ttggtggagg tcaggcagac ttgatattga ctgagggcga ccttttaaca
     8221 gctggtgtgg agatttctgt tcaacctcca ggtaagaaaa tccagtcgct taacctcatg
     8281 agtggtggtg aaaaagctct atcggctctt gccttgcttt tctccattat tcgtgtcaag
     8341 accattcctt ttgtcatctt ggatgaggta gaggctgcgc tagacgaagc caatgttaaa
     8401 cgtttcgggg attatctcaa ccgctttgat aaggacagtc aatttattgt cgtaacccac
     8461 cgtaagggga ccatggcagc ggccgattct atctatggag tgaccatgca agaatcgggt
     8521 gtttcaaaga ttgtttcagt taagttaaaa gatttagaaa gtattgaagg atgacaatta
     8581 aactagtagc aacggatatg gacggaacct tcctagatgg gaatggacgc tttgatatgg
     8641 atcgtctcaa gtctctcttg gcttcctaca aggaaaaagg gatttacttt gcggtggctt
     8701 cgggtcgggg atttctgtct ctggaaaaat tatttgctgg tgttcgtgat gacattattt
     8761 tcatcgcgga aaatggcagt ttggtagagt atcaaggtca ggacttgtat gaagcgacta
     8821 tgtctcgtga cttttatctg gcaacttttg aaaagctgaa aacgtcacct tatgtagata
     8881 tcaataaact gctcttgacg ggtaagaagg gttcatatgt tctagatacg gttgatgaga
     8941 cctatttgaa agtgagtcag cattataatg aaaatatcca aaaagtagcg agtttggaag
     9001 atatcacaga tgacattttc aaatttacaa ccaacttcac agaagaaacg ctggaagctg
     9061 gtgaagcttg ggtcaatgat aatgtccctg gtgtcaaggc tatgacaact ggctttgaat
     9121 ctattgatat tgttctggac tatgtcgata agggtgtagc tattgttgaa ttagctaaaa
     9181 aacttggtat cacaatggat caggtcatgg cttttggaga caatcttaat gacttacata
     9241 tgatgcaggt tgtgggacat cctgtagctc ctgaaaatgc acgacctgaa attttagaat
     9301 tagcaaagac tgtgattggt caccataagg aacggtcggt tatagcttat atggagggct
     9361 tataatggca gatataaaat tgattgcatt ggacttggac gggaccttgc tgactactga
     9421 taaaaggctg acggatcgta ccaaggaaac cttgaaagct gcgcgtgatc gtggtatcaa
     9481 ggtcgtattg acaactggtc gtcccttaaa agccatggat ttctttctcc atgagttagg
     9541 gactgacggt caggaagatg agtataccat tacttttaat ggtggattag ttcagaaaaa
     9601 tacaggagaa atccttgata aaacagtctt ttcatatgat gatgtggcac gtttgtatga
     9661 agaaacagag aaattatcac tgcctctcga tgccatctca gaaggaacag tttatcaaat
     9721 ccaatcggac caagaaagtc tttatgccaa attcaatcca gctttgacct ttgttccagt
     9781 ggactttgaa gacttatcta gtcaaatgac ctacaacaaa tgcgtgactg cctttgctca
     9841 agaacccttg gatgcagcca ttcagaagat ttctccagaa ttgtttgacc aatatgaaat
     9901 ctttaaatca cgtgaaatgt tgctagaatg gtcaccaaag aatgttcata aagcaacagg
     9961 tttggcaaaa ctaatcagcc atcttggaat cgaccaaagt caagtgatgg cttgtggtga
    10021 cgaggccaat gacctctcta tgattgaatg ggcaggtctt ggtgttgcta tgcaaaacgc
    10081 tgttcctgaa gtaaaggcag ccgcaaatgt agtgacgccg atgaccaacg atgaggaagc
    10141 tgtcgcctgg gctatcgaag aatatgtgct aaaggagaac taagatatgg gattgtttga
    10201 ccgtctattc ggaaaaaaag aagaacctaa aatcgaagaa gttgtaaaag aagctctgga
    10261 aaatcttgat ttgtctgaag atgttgatcc taccttcaca gaagttgagg aagtttctca
    10321 ggaagaagca gaggttgaaa ttgttgaaca agctgtgttc caagaagagg aaatccaaga
    10381 cacagttgaa gaaagtctgg atttagagcc agttatagaa gtttctcaaa aagaagtcaa
    10441 agaatttcca cactcagaag aagggaatac tgagtttcta gagactgtag aagaaaataa
    10501 ttctgaaatt cttgaagcag aaaggcctca aacagaagaa actgttcagg aaaaatatga
    10561 ccgcagtctt aagaaaactc gcacaggttt cggtgcccgc ttgaatgcct tctttgctaa
    10621 cttccgctct gttgacgaag aatttttcga ggaactggaa gaactgttga ttatgagtga
    10681 tgttggtgtc caagtcgctt ctaacttaac ggaggaacta cgttacgaag ccaagcttga
    10741 aaatgccaag aaacctgatg cacttcgtcg tgtcatcatt gagaaattgg ttgagcttta
    10801 tgaaaaggat ggtagctacg atgaaagcat ccacttccaa gataacttga cagttatgct
    10861 ctttgttggt gtgaatggtg ttgggaaaac aacttctatc ggaaaactag ctcaccgcta
    10921 caaacgagct ggtaagaagg tcatgctggt tgcagcagat accttccgtg cgggtgcagt
    10981 agctcagcta gctgaatggg gccgacgagt agatgttcca gtagtaactg gacctgaaaa
    11041 agctgatcca gccagcgtgg tctttgatgg tatggaacgt gccgtggctg aaggtatcga
    11101 tattctcatg attgatactg ctggtcgtct gcaaaataag gataacctta tggctgagtt
    11161 ggaaaagatt ggtcgtatta tcaaacgtgt tgtgccagaa gcaccacatg aaaccttctt
    11221 ggcacttgat gcatcaacag gtcaaaatgc cctagtacag gccaaagaat tttcgaaaat
    11281 cacaccttta acgggaattg ttttgactaa gattgatgga actgctcgag gaggtgtggt
    11341 tctagccatt cgtgaagaac tcaatattcc tgtaaaattg attggttttg gtgaaaaaat
    11401 cgatgatatt ggagagttta actcagaaaa cttcatgaaa ggtctcttgg aaggtttaat
    11461 ctaatcagaa gcaaaaatcc tgcaaggcat aaacttgcag gaaatttttt tattctaagc
    11521 gaccatcttg acgataggcg atatctggtt gccaagtcca tttggcaccg aatttttcaa
    11581 gtaggtcaaa gctggcttga ggtcccatgc ttccagcttt atagtcatga agtggggcac
    11641 cattttcatc ccagagctct tcaatacggt caatcaactt ccatgatgca ccaacttcat
    11701 cccagtggct aaagttagtt gagttgttat ttaggacatc ataaatcaat ttctcgtatg
    11761 gttctggaga agcaccagtt gcagtcgcat ctgtacggta atcaagtgag ttaggagcca
    11821 agttaaattc ttctcctact tgcttcccat ttaggctaag agagaagcct tctgttggtt
    11881 gaatatagat ggtcaaaata tttggagcaa gtggttctcc aaagatagaa tccatttgtt
    11941 taaagacgat gttgacatga gttccttttt cagtcagtcg tttacctgta cggaaaaaga
    12001 aaggaacact acggaatcga tcgctgtcta caaagaaggc accagatgta aaggtttcag
    12061 ttgttgattc tggattcaca tttggctcgc tacgataaga gatgtatttc atgccatcaa
    12121 tcttaccaga gcggtattgc ccacggataa agtgttcttt gagttcttca tcagttggat
    12181 gatagaggtt tttaaagacc ttaatctttt cagcacgaat ctcgtctttt gtgaagcttg
    12241 ctggtttgtc catggcgagg agcgaaagaa gttgtagagt gtggttttgg accatgtcac
    12301 ggagggcacc ggattggtca tagtagccac cacgttcttc tacacccaag cgctccgcaa
    12361 aggtaatttg aacattgtcg ataaaatcct tgttccaaac gttttcaaaa atcaagtttg
    12421 caaagcgaac tgcaaagatg ctttggatca tttccttacc aagataatgg tcgatacgga
    12481 aaatttgttc ttcgtcaaat gttgctagga gttcgtcatt caacttgctt gcagttgcgt
    12541 aatctgtacc aaatggtttt tcaacgatca agcgctcaaa acctttgcca tcgacaatgt
    12601 tttcagattt gaggtgtttg gcaatggttc caaagaactg aggtgccata gacaagaaga
    12661 agagcttatt gtgttcagct tggtattttt cattaagctc agcttgtaat tgacgcaaag
    12721 caatataatg ttccgaatca ttgacatcat ggctttgata gtagaagtgg ctagcaaatt
    12781 cttgggcttg ctcggtacta tctgccaaat caaggatgga ctcgacaact acagattcaa
    12841 aatattcctt actccaaggt ctacgggcag ttccaataac ggcaaagtgc ttggaaagat
    12901 tgccggattt atatagtcta aaaagggaag ggtagagctt gcgtttagcc aggtctccac
    12961 tcgcaccgaa aattgtaaca ataaccttag atgacatcta gctacctaat ttctattttt
    13021 attcctagtc ttgctaggta tgaggaaacc tcatttcata aacttaattc taacataatt
    13081 ttccgaaaaa tcaaaaattc caatacgaag tagaaaaact gcaaggaaat ccttacagtt
    13141 tgagtttaga cgtttaagac cttatctaag aactctttca gacgagggtg ttgtgggtta
    13201 tcaaagattt ggtcaggtgt tccgtcttca aggaactcgc catctgcagt aaagataacg
    13261 cggttggcaa cctgacgagc aaatcccatc tcatgggtta cgataatcat ggtcatacct
    13321 tgctcagcca attccttcat aacgttaagt acgtctccaa ccatctcagg gtcaagggca
    13381 gaagttggtt catcgaagag catgatgtct ggattcattg ctaggccacg agcgatggcc
    13441 acacgttgtt tttgaccacc tgataggcta tctggattgg cattagcttt atctgctagt
    13501 ccaacctttt caagcaactc cattcccaat tcctcagctt cttccttagt catcaacttg
    13561 tgctcaatag gagcaaaggt gatgttgtcc aatacagaca tatgagggaa gaggttgaag
    13621 tgttggaata ccatgccgat attttcacgg acgtggtcaa cattggttgt tttttcagtt
    13681 aaatcatagc cgttcacagt gatgtgaccg ctagtgactt cttctaaaag attgaggcta
    13741 cggaggaaag ttgacttacc agaacctgaa ggaccgatga tacaaacaac atctccttca
    13801 tagaacttag tcgtaattcc ttttaggact tcattttttc catagtgctt gtgtaaatca
    13861 tttacatcaa tttttaattt tgccattaac gaatcctctt ttctaagcgt ttcgctagtc
    13921 tagtcaaaag tgtgataatt acaagataga agatagcaag gattgcatac atcttgaaac
    13981 tttggtagtt acgagcaatg ataatcttac cagtttggaa gagttcaacc aaaccgatag
    14041 cagatacgat agttgtatct ttaagagcga taacgaattg gttgacaaag tttggcaaca
    14101 tcaatttagt tgcttgtggc aagataatct tacgcatggt ttttccataa gagataccca
    14161 agcttcggct ggcttccatt tggccaactg gaacggcctg aataccacca cgaacgattt
    14221 cagcgatata agcagccgca ttgagtgaga gggcaatggt tccagctaca aagtcgttaa
    14281 ttgggctttg ttggcctgtg atagactcga tgaagtttgg aattccccag aagatgaagg
    14341 ctgcaagaat catcaatgga ataccacgaa taacgtcaac gaaaatctca gagatgacgc
    14401 gaagagattt gtatgggcta acgctaaaca taccgaagat aattccgatg acaatggcaa
    14461 tagcaaatga gataagagct agagcaagag tgataccaag accgctaagg agttgtttgt
    14521 agttgttttg aagcaagccc cagagcgttg tttcgtcaac agtacttgtt gaagcagttg
    14581 aagattcgct agctaggtat ttgtcaagaa tcttttggaa ttcaccgttt gctttaaggt
    14641 ttgcaagtcc gttgttgaac atttcaatca gttctggatt tgctcctttt ttaacggcaa
    14701 aggctgtttc accgattgga gttccagaga ttggagtttt caatttttga ccttggctga
    14761 tagaatattt gagaacaggt tcatcatcca taacggcatc aatggcacca gtgtttaaac
    14821 tgtcatacat tgaagaacca tcagcaaagg ttttgatttt gtaaccgtat ttgctttgat
    14881 tttctgttag gaaggtttga gaagcagttc cgtttttaac accgactgtc tttcctttta
    14941 gatcttcata agaagcaata ttgcttgatt ctttgacacc aagaatggta ttagcagtgt
    15001 agtatgattc tgagaagtca aaagttgcct tacgagcatc tgtgacagac atcccagcaa
    15061 tgataccatc ggcttgacca gcttggacag cactgatagc agcatcaaaa ccagggttgg
    15121 tgatttcaat ttcaaaacct tggtctttag cgattgcctt aatcaattcc atatcaatac
    15181 cagtgtattg gttgcttgaa ttttggaaaa caaaaggtgc aaaagaagaa tcgctggcaa
    15241 tgatatattt agccttaaca ggaatagctt ttaatcctgc gagagtagtt gtagttggca
    15301 ctgctgaaga tgatgaagca gtccatttct tgataatttt atcaagacta ccatcttttt
    15361 tcatttcagc caaggcttgg ttaaattcag taaccaggtg ctcgtattta cttccttttt
    15421 tcacaccgaa agcaaaactt cctacagctt caccatccat ttcaatatgg agatcttgac
    15481 cttggttaat ggcatattcg ataacaggtt tgtcatccat catggcatcg atggcaccag
    15541 cactcaagct gttgttcatt aaatcaccag tgtcaaatgt tttaatagta aagccgtatt
    15601 tatctttgat tgtttcaagg aaacgttgag cggcagttcc gtttttaaca ccaacggttt
    15661 tgccagttaa ttggtcgtac ttgctaattt tgtgtgactt tgtagtagca atgacaactt
    15721 ttgtatcata gtaagtatca gacatggtga agactttttc acgttcttta gtctttgtca
    15781 tccctgccat gatagcgtcg gcttgcccag cttgaaccgc attgactgct gcgtcaaatc
    15841 caggatagga catctgaatg ttccagcctt taatctcagc gactttgtta ataatgtcaa
    15901 catcaattcc tttataagtt tgatctgaat ctttaaactc aaaaggtgca taggcggtat
    15961 cagaaacaat cttaatcgtt tctgctttgg caatacctaa tgagaaaatt gggaataaaa
    16021 ttagcaaaaa tgctagaaat tttttcttca tttttagtct ccttttccga atattctctc
    16081 attatatcag aaaaagtaaa aaaaggcaaa ttgttatatt tttcgtgtca gaaaatataa
    16141 cattgatttt tccttttctt tcttgaattg ctattaaaaa gtgctataat aatagtatat
    16201 atagaagaaa agaggacggg gatatgaaga acaaaagaat atttaaagac ttccaagctt
    16261 caaaaatgag tttaaacatt tacacaagcc ccttgttagc ctttgttttt gtcttcatag
    16321 gagagtttgt ggcttttact ttgtatggta ttggcttgtt agctctcatc ggacttgcta
    16381 gaaattttgg agaggctggt caaaatcttg caagctactt gcagaccttg caacagagct
    16441 tgacggataa aacaagtgac tttcgtttaa ttttaggatt actggccttt ggttttattc
    16501 ttaacactgt gttcagatgg acaagaaaag ttgagaaaag acctattcga accttgggat
    16561 tttatagaga gaatttcctc agcaatcttc tgaaaggatt tagtctaggc ttggcacttt
    16621 ttcttctgac cttgttaggt ttagtggtct taggtcaata tcgtttggaa tccattcact
    16681 tgaatcctta ttctcttgcc tttgtcgtct ttactatccc attttggatt ttacagggga
    16741 cagcagaaga agtggtggcc cgtgcttggc tacttcctca attggcctca agaaccaatc
    16801 taaaactagc tattcttata tctagcctgt tctttaccct gcttcatatg ggcaattcta
    16861 gcctcacccc tctatctcta gtaaatctct ttttattcgg agttgccatg gctctttatc
    16921 ttctcaaaac tgatacagtt tggggtgttg caggtattca tggtgcttgg aattttgctc
    16981 agggtaatct ctttgggatt ttagttagtg gtcaaccgtc aggaacgtct ctgatgacct
    17041 ttttaccaca aggcaatcaa gattggctat caggtggttc ttttggcata gaaggttcca
    17101 ttatgacaag tctggtatta ctactgctga ttgtctatct tgctaataaa ttaaagaaag
    17161 aaaatgaaag gatgtgactt cggtccgtcc ttttcttcgt gaaaatacta taagtatgct
    17221 aaaataggaa tagcacatgg agagaggatt cttatgatca atcacattac agataatcaa
    17281 tttaaactag tatcaaaata tcaaccatca ggagatcaac cccaagctat cgagcagttg
    17341 gtggataaca ttgagggggg agaaaaagct cagattctga tgggggcgac tggaacaggg
    17401 aagacctata ctatgagtca ggtcatttct aaagtcaata aaccaactct ggttattgcc
    17461 cacaataaaa ctctggctgg tcagctctat ggggagttta aggaattttt ccctgaaaat
    17521 gcagttgagt atttcgtatc ctactatgat tattaccagc cagaggccta tgtcccttct
    17581 agcgatacct atattgagaa ggatagttct gtcaatgacg agattgacaa gcttcgccac
    17641 tcagctacct cagccctttt ggagcgtaat gatgttattg tcgtggcctc agtctcttgt
    17701 atctatggtt tgggttcgcc caaggaatac gctgatagtg tcgttagtct ccgtcctggt
    17761 ctagagattt ctcgtgataa actcttgaat gacttggtcg atattcagtt tgaacgtaat
    17821 gatattgatt tccaacgcgg aagatttcgt gttcgtgggg atgtggtaga gattttccca
    17881 gcttcccgag atgaacatgc ctttcgagta gaattttttg gagacgaaat tgaccgtatt
    17941 cgtgaagttg aggctctgac aggtcaggtg ttgggagaag tggatcattt agcgattttc
    18001 ccagcgacac actttgtgac caatgacgac cacatggaag ttgccattgc aaagattcag
    18061 gccgagttgg aggagcagtt agctgtcttt gaaaaggaag gtaaactgct tgaagcccag
    18121 cgtttgaaac agcggacaga gtatgatatc gaaatgttgc gtgagatggg ctataccaat
    18181 ggggttgaaa attattctcg ccacatggat ggacggagcg aaggagagcc tccttatacg
    18241 cttctcgact tcttcccaga tgatttcttg attatgattg acgagagtca tatgaccata
    18301 gggcaaatca agggcatgta caatggagac cgttcgcgta aagaaatgct ggttaattat
    18361 ggtttccgtt tgccgtctgc tttggacaat cgtcctctcc gtcgggagga gtttgagagt
    18421 cacgttcatc agattgttta cgtttcagcg acacctggtg actatgaaaa tgaacagacc
    18481 gagacagtga ttgagcaaat cattcgtcca acgggactct tggatccaga ggtggaagtc
    18541 cgtccgacta tgggacagat tgatgacctc ttgggtgaaa tcaatgcccg cgttgaaaaa
    18601 aatgagcgta cctttatcac aactttgacc aagaaaatgg cagaggactt gaccgactac
    18661 ttcaaggaaa tgggtatcaa ggtcaagtac atgcactcgg atatcaagac cttggaacgg
    18721 acggagatta tccgtgacct gcgcttgggt gtctttgatg tcttggtcgg aattaacctg
    18781 ctccgtgaag gaattgacgt tcctgaagtg agcctcgtag ctattctcga tgctgacaag
    18841 gaaggtttcc ttcgcaacga acgtggactc atccagacta ttggacgtgc tgctcgtaac
    18901 agtgaaggcc atgtcatcat gtatgcagac acggttaccc agtctatgca acgtgctatc
    18961 gatgaaactg cccgccgtcg gaaaattcag atggcctata atgaagagca tggtatcgta
    19021 ccacagacaa tcaagaaaga aatccgtgac ctgattgccg tgaccaaggc agttgctaag
    19081 gaagaggaca aggaagtcga catcaatagc ctcaacaaac aagagcgtaa agaactcgtc
    19141 aagaaactag aaaaacaaat gcaagaagcc gtcgaagtgc ttgactttga actggcggct
    19201 cagatccgtg atatgatgtt ggaagtcaag gccttggatt aggggaatag tatgatttat
    19261 ttaagaaagt taaagagaga agatttgatg tctttatggg aaatggctta ttcacaactt
    19321 aatccagttt ggaaacagta tgatgctccc tattatgatg attatcagta tttttcaaat
    19381 tttaaagaat tcgaactaca aaaatcagaa tccattttaa gcaactcaaa tcgccttggt
    19441 atttttgttg atgataaact agttgggact gtttcgcgtt attgggtatg taaacaaaca
    19501 agatggatgg aattgggaat tggtatttat gataaaaaat tctggaacac tggtattggg
    19561 aaagttgcta tgttgcagtg gatagatagg acgtttcagg attacttgga gttggagcat
    19621 ctgggtttga caacttggtc agggaatctt ggtatgatga aacttgctga aaaattaaga
    19681 atgaaaaaag aagctcatat tccaaaagtt cgttattatc aaggtaaata ttttgatagt
    19741 attaaatatg gtattttgag agaagactgg gagaaaataa atgacggtta ttatcaaatc
    19801 aatggaaact cctaaagaga tagaaggtaa atcccttgtt cactggcaaa tgtggagaga
    19861 ggcttatgat gaccttttgc ctgcagaatt tcaggagaca atgacattag aaagatgtcg
    19921 actctttagt caaaagtatc cagaaaatac attgattgcg ataggtgatc tgaaggtagt
    19981 tggttttatc agttatggta actttcgtga tgagactatg caagctggtg aaattattgc
    20041 tttatatgtt ttaaaagact attatggaaa aggtatcgca caaaagttaa tgaaagcagc
    20101 tttgactgct cttaatcatt tttctgaaat tttcttatgg gtattgaaag ataacaagcg
    20161 cgccattgct ttctatcaaa aaatgggttt tacttttgat ggacaagaaa aaatacttga
    20221 acttggaaag cctataaagg aaaaacgaat ggtgttctat tctaaataat tttaaaaaag
    20281 taaaagataa tatctctggt agtaagtctg aaaatttaat aaattagaaa gcgagtaaat
    20341 ttatgtcccg ttcccaatta acaattttaa caaatatctg tctgattgaa gacctcgaaa
    20401 ctcagcgcgt ggtgatgcag tatcgcgccc ctgaaaacaa tcgctggtct ggttatgcct
    20461 ttcctggagg tcatgtagaa aatgatgagg cttttgcgga gtctgtcatt cgtgaaatct
    20521 acgaagaaac agggttgact atccaaaatc ctcaacttgt cggcattaaa aattggccac
    20581 tagatacagg tgggcgctat attgtcattt gttataaggc gactgagttc tctggtagcc
    20641 ttcggtcttc agatgaagga gaagtttctt gggtgcaaaa agaccagatt ccaaacttgg
    20701 atctggccta tgatatgcta ccattgatgg aaatgatgga agctcccgac aagtcagagt
    20761 ttttctaccc tcgccgtaca gaagacgatt gggaaaagaa aatcttctag tcttttacta
    20821 aataacctag ctgatccaag gcctcctcga tatagtggag gtcttgttgt gtttcggctt
    20881 cgactaggtg gtaatggatg ccatctgtca attcagatag aggtctaaag tcagaatgct
    20941 cgacttgttc tagaaaatgt tgcacatctc tgcgacaaga cagtttaagc aaggtttcaa
    21001 tttctccata aacgggatgg tcaatcaagg tattctggac atgcccacca ttatcgacaa
    21061 tagcaaggag ttcctgaccg atttcttcaa cttcatgttt cactttgaaa agtttgtgaa
    21121 cataaggatt ggtatcaatt tgcttataga tgtagccacg attggtggat aggataggag
    21181 cgccatcggc tctcaaaatt gcaatgtcct gcacaatgac ctgacgtgtg acatgaaaat
    21241 gttccgccaa actttggcca ttaagggctt taggagcttc tttcaagagt tggagcaggg
    21301 cttgtttgcg atcttttgtc atagcttttc cttttaacgg cgttttcgaa gcactttata
    21361 gacagctagt gctaatgtat agtctaccat actatggata attgtgccaa atccaactag
    21421 tacaaataga acatagaaca tattttctac attggtaccc gaagttgcgt aaaaaaggac
    21481 acaggctaat acttcagcaa gggcatgaac aacagccaaa acaaaattga aaacccagga
    21541 agattttggt ttatctaggg tatcggggaa tttttgtagg taaagagctc ctaaagcacc
    21601 aaaagatata tgggaaaaag cccgaaaaac gataaccatg ggatagccag ccatcaaaaa
    21661 tccaaaacta gaggctagga tgacaaaaac tgccatcaag ggcgacaaga acatggctat
    21721 aaaaatagcg atgtggctcc ccaaagtata ggaagcaggt ggaatgacaa tcttgaaagg
    21781 cataacaatt ggaatcaaaa tcgcaatagc cgttaaaagg gctgtcattg tcataaattg
    21841 tgtctttttc cgtgtattca caagaatctc ctttttaact gcatatacac tagtatggta
    21901 caataaacca gacaataaag caagaattta cttgggttta tagatcattt tttagttaaa
    21961 agttatagta gatggaaact agaatagtcc acctctactt ctaaaacatt gttagcgatt
    22021 tgactgtcct gatcgatttg tcctgttctt atttcgtttt actatagtaa agatttcatt
    22081 aaaaagaaac tgtatagagc aaaatctcca ccttcaggtt tgaaagcgga gattgttttt
    22141 attttttcaa ggtttgtagt cgtggaacaa tggctagggt tagaattgca gaaatgacca
    22201 attcagcaat tgaatttgtt gagataacgg ttgccagaag aagttggata tttccattat
    22261 aaacatttcc aaataggaag aagattcctc caaggacaaa gatagtattt gtcaaggaac
    22321 caagggctcc agctaaaatc agaccagtct tgtttttcat cagtttatag actaagtaag
    22381 gagttaaacc aatcaaaata cgtgggacga tggcaatgat agctgagtag atgtttccgt
    22441 ttggtacgaa gggagagaag aggtagcttg tcggtagaat cgtaatcgtg ttaaccgtca
    22501 agctaagtaa tcccatcaaa aatccaagtg taaccccaac tcgtggacca taaataatgc
    22561 tggcaataat gacaggaata tgaacaatgg tcggtttgat tggaaatgga aaaaggttaa
    22621 agataagtga gctcagaaag tgtatcacga gcatggtagc aaaaaagata gcaatgggtg
    22681 caatattaga gcgttttttc atcgatagtt tcctttattc tttctaaaat aattgtgagg
    22741 tcagctaaag ctcctcgtcc gtggtctcca caagctagta gggattcctt aggagcaatc
    22801 agctgatagc cgtaggtttc taatgttttc agattattct gagttactgg atggtcatac
    22861 atttttgtat tcatagcagg agctattagt ttgggaatat gacttggtag ggctagagct
    22921 gtactggtta ccatgttgtc cgcaaatccg tgagctagtt ttgcaatagt gttagcagtt
    22981 gcaggtacca cgataaataa atctgctttt tttccaagtt cgatatgatt gacctgatca
    23041 ggatagggtt ccttcatgac atccaagtgg acaggattct gtgagagtac ctgtagtgtc
    23101 aaaggttgga taaactctgt agcagcctga gtcattaaga cagtgacttg atggccttgt
    23161 ttttttagag aactgactaa atctgccgac ttataagagg cgattgaacc cgttacagcc
    23221 aagagaatgt ttgccatagt tttcctttct aagaatgata ggcttgaatt ttttcaagga
    23281 ggagttctgc aatttcttct ttagtctgga ctgtttgaag ctgatttttc tcaacaaata
    23341 tagctcggtg ctgatctgct gaaatttgag tcaggtcatt cgcgatgatt aaatctgctt
    23401 gattcttgat aagacttttt cgtgcaatgt caaccagatg atcttcggta acatcaacca
    23461 gcagtttgaa accaatcaga tgaatagtgg gattccattc cttgactagg gatatgattt
    23521 tgggtgtctt tttaaggaac aaaacctgaa cctcatcagt tgaagaaatc ttggcctgat
    23581 gattctgctt gcttaaaaat tcttttagat tggagctagc ctgaacttcc tcaagccctg
    23641 tcatataaac aggagtgtag tcagaaacag ccattgagtg gatcaagacc tgataatcct
    23701 gaacacgttc ttgcatttct attagaaggt ccttggtatt ggtaatttct cgaatactta
    23761 ggttaggatg aggctctggc ttcagagctc gttttgtcgt aattaaacaa acttcatgcc
    23821 ctgcagaaag caaagtctct gtgataattt tccccaagtg acctgtagaa tggttagtga
    23881 tagagcggac gctatcgata gcttcactgg taccgcccga tgtaactaaa attttcatag
    23941 cactattgta cacaaaaata agcggtaagt aaaatgaaag tgataaattt ttggtaaaaa
    24001 cgaagattta ctatagtttc aaactataaa gccatataaa atttaagaaa ggactctaaa
    24061 agccttaaaa acagagatat ttacgaacgt ttagagagtt ttaggatgtt aaaaatcttg
    24121 ttttgtgata taatgaatta tcatataaga ggttagagga attttgaatg aaaacagata
    24181 ttgaaatcgc acagagtatt gagttgaagc caattgttga tgttgtagag aaacttggta
    24241 tttcttatga cgatttggag ttgtacggaa agtacaaggc taaactcagc tttgataaaa
    24301 ttcgtgcagt tgagagcaat ccagtcggta aattgatctt ggttactgcc atcaacccaa
    24361 cacctgcagg tgaaggaaag tcgacgctta ccattggtct tgcggatgcc ttgaacaaga
    24421 ttggcaagaa aaccatgatt gctatccgcg aaccgtctct tggtccagtc atggggatca
    24481 agggtggtgc tgctggtggt gggtatgcac aagttctgcc aatggaagac atcaacctcc
    24541 actttactgg agatatgcat gctattacaa ctgccaacaa tgccctttct gccttgattg
    24601 acaaccactt gcaccaaggg aatgagctgg aaattgatca acgtcgtatc ctctggaaac
    24661 gcgttgtgga cttgaacgac cgtgcgctcc gccatgtgac tgttggtctt ggtggtcctc
    24721 taaacggtat tccacgtgag gatggttttg atattacagt tgcttcagaa atcatggcaa
    24781 ttctttgctt ggcaacggac atcgaggact tgaaacgtcg tttggcgaat atcgttattg
    24841 gttatcgcta tgaccgtacg cctgtttctg taggtgattt gcaggttgag ggtgccttgg
    24901 ctttgatttt gaaggatgct attaagccaa acttggttca gacaatttac ggtacacctg
    24961 cctttgtaca cggtggtcca tttgccaata tcgctcatgg ctgtaactct gttttggcga
    25021 cgacaacagc ccttcacttg gctgattaca ctgttactga agctggtttt ggtgcggacc
    25081 ttggtgctga gaaattcctt gatatcaaga caccaaactt gccaacatct ccagatgcag
    25141 ttgtcattgt cgcaaccctt cgtgccctta agatgaatgg tggtgtggct aaagacgctc
    25201 tgactgaaga aaatgtagag gcagttcgtg caggttttgc taacttgaaa cgccacgttg
    25261 aaaatatccg taagttcggt attccagcag ttgtagctat taacgaattt gtatctgata
    25321 cagaagctga aattgcagtc ttaaaagaac tctgtgcctc aatcgatgta ccagttgaat
    25381 tggctagtgt ctgggctgat ggagcagaag gtggagtagc acttgccgaa acagttgtta
    25441 agacaattgc tgaaaatcca gctaactata aacgtttgta cgataatgcc ctttctgtcc
    25501 aagaaaagat tgaaaaaatt gtcactgaaa tctatcgtgg tagcaaagtg aactttgaga
    25561 agaaagctca aacacaaatt gctcaaatcg ttcaaaacgg ttgggacaaa ttgccaatct
    25621 gtatggctaa aactcaatac agtttctcag acaatccaaa tgcgcttgga gcaccagaaa
    25681 actttgaaat taccattcgt gaattggtac caaaattagg tgcaggcttc atcgttgcct
    25741 taactggtga tgttatgacc atgccaggtc ttccaaaacg tccagcagct ctcaacatgg
    25801 atgttgaaag cgatggaact gtactaggct tgttctagtg gattgaaatt gactttaagt
    25861 gagtttggaa ataatatcca agctcatttt ttctcagact gcaagcagtt catcaataag
    25921 atttatactc ttcgaaaatc tcttcaaact acgtcagctt caccttgccg taggtatatg
    25981 atactgactc tgtcagttct atccacaacc tcaaaacagt gttttgagca acctgcggct
    26041 agcttcctag tttgctcttt gattttcatt gagtataagt agatagaaaa gttatatact
    26101 atctattgaa aatattataa atcagataca aagacaggtg aaaccttctg tgttatacta
    26161 gagatatgtt agatttgaaa gaatacggta tcgtcatgtg gccggaggag aaagtcattt
    26221 ctttccgtga gaaacttctc gcttggtatg atgaaaacaa aagagatttg ccttggagga
    26281 gaagtaaaaa tccttatcac atctgggtat ctgaaatcat gcttcagcag accagggtgg
    26341 atacagttat cccttactac gaaagattcc tggactggtt tccaactgtc gaaagtctgg
    26401 caactgcgcc tgaggagagt ttactgaaag cttgggaggg cttgggctat tattctcgag
    26461 ttcgcaatat gcaggctgca gcccagcaga ttatgactga ctttggtggc caatttccaa
    26521 atacctatga aggaatttcc agcttgaaag ggattggacc ttacacagca ggagccattt
    26581 ccagtattgc ttttaacttg cctgagccag ctgtagatgg taatgtcatg cgggtcttgg
    26641 cgcgtctgtt tgaagtcaac cacgatattg ggattccaag taatcgaaaa atttttcagg
    26701 caatgatgga gatcttgatt aatccggatc gtccgggtga ttttaatcaa gccttgatgg
    26761 acttagggtc tgatattgag tctcctgtaa atcccagacc tgaagaaagc ccagtcaagg
    26821 actttagtgc ggcatatcag aatggaacca tggaccgtta tccaattaaa tctcctaaga
    26881 aaaagccggt tcctatttat cttaaagcct tagttgtgaa aaattctcaa ggacaatttt
    26941 tacttgaaaa aaatgaaagc gaaaagctct tggcaggttt ttggcatttc ccctttatag
    27001 aagttgataa cttttcgcaa gaagagcagt ttgacctctt tcatcaggtt gcggaagaaa
    27061 gtgtgaactt tggccccagt ccagaagaga gtttccagca ggactatgac ctagatgttg
    27121 attggcttga tgtttgtttt gatacagtcc agcatgtttt tagtcatcga aaatggcatg
    27181 tacagattgt agcaggtcag gtgagtgact tccatgattt ttcagatagg gaagttcgtt
    27241 ggctttcacc agaagaattc aagaattacc cacttgccaa accccaacaa aaaatctggc
    27301 aggcttatgc acaagccaac ttagacagta gccaagacta gctattgtgt cttctgacta
    27361 ttttttggta taatagtaga gaaaaaggtg aacatatgaa aaaaatacta attgtagatg
    27421 atgagaaacc aatctcggat attatcaagt ttaatatgac caaggaaggt tacgaagttg
    27481 taactgcttt taatggtcgt gaagcgctag agcaatttga agcagagcaa ccagatatta
    27541 ttattctgga tttgatgctt ccagaaattg atggtttaga agttgctaag accattcgta
    27601 agacaagcag tgtgcccatt cttatgcttt cagccaaaga tagtgaattt gataaggtta
    27661 tcggtttgga acttggggca gatgactatg taacgaaacc cttctccaat cgtgagttgc
    27721 aggcgcgtgt taaagctctt ctgcgtcgtt ctcaacctat gccagtagat ggtcaggaag
    27781 cagatagtaa acctcaacct atccaaattg gggatttaga aattgttcca gacgcctacg
    27841 tggctaaaaa atatggcgaa gaactagact taacccatcg tgaatttgag cttttgtatc
    27901 atttagcatc gcatacaggt caagtcatca cgcgcgaaca cttgcttgag actgtctggg
    27961 gttatgacta ttttggtgat gtccgtacag ttgatgtgac tgtacgacgt ctgcgtgaga
    28021 agattgaaga tacgcccagc cgaccagagt atatcttgac gcgccgtggt gtagggtatt
    28081 acatgagaaa taatgcttga tttactgaaa caaaccattt ttaccagaga ttttatcttt
    28141 atcctgattt tgttaggttt catccttgtt gtgaccctct tattactgga aaatagacgt
    28201 gataatattc agttgaagca aatcaatcaa aaggttaaag atttgattgc aggagattat
    28261 tccaaggttc ttgatatgca aggtgggtct gaaatcacca atattaccaa taatttgaat
    28321 gacttgtcgg aggttattcg tctcactcag gaaaatctag aacaagagag taagaggcta
    28381 aatagtattc tgttttatat gacagatggg gttcttgcga ccaaccgtcg gggtcagatt
    28441 atcatgatta acgatacagc caagaagcaa ctggggttgg ttaaggaaga tgttctgaat
    28501 agaagcattt tggaattgct caagatagaa gaaaactatg aattgcgtga tttgattacc
    28561 caaagtccag aattgttgct agattcccaa gatatcaatg gcgaatattt gaaccttcga
    28621 gttcgctttg ccttgatacg tcgagagtct ggctttattt caggtttggt ggctgttttg
    28681 catgatacga cggagcagga gaaggaagaa cgcgaacgaa gactctttgt ttccaatgtt
    28741 agccatgagt tacggactcc tctgactagc gtaaaatcct atcttgaagc cttggatgag
    28801 ggggctttgt gtgaaactgt agcaccagac tttatcaagg tttctcttga tgagaccaac
    28861 cgtatgatgc gcatggtgac ggatctcctc catctttcac gtattgataa tgctaccagt
    28921 cacctagatg tggaactgat taacttcact gcttttatta cctttatcct caatcgtttt
    28981 gacaagatga aaggacagga aaaggagaaa aaatatgagt tggtgagaga ttatcccatc
    29041 aattctatct ggatggaaat tgatacagat aagatgacgc aggttgtcga caatatttta
    29101 aataatgcta ttaagtattc gccagatggg ggtaaaatca ctgtcagaat gaagacaact
    29161 gaagaccaga tgattttatc catttctgac cacggtttgg ggattcctaa gcaggattta
    29221 ccacgtatct ttgaccgttt ctatcgtgtg gatcgtgcta gaagtcgtgc acaaggtggt
    29281 acaggtctag gactgtctat cgctaaagaa attatcaaac aacataaggg ctttatttgg
    29341 gccaagagtg aatacggcaa gggttcaacc tttaccattg tgctccctta tgataaggat
    29401 gcagtgaaag aagaagtatg ggaggatgaa gtagaagact agaatgagtg aaataggctt
    29461 taaatacagt attttagcgt cgggttccag tggaaattct ttttatctgg aaacctcaaa
    29521 aaagaagctt ttagtagatg caggcttgtc tggcaagaaa attaccagtc tgctagctga
    29581 aattaaccgt aagccagaag acctggatgc catcttgatt acccatgagc attcagatca
    29641 tatccatgga gtaggcgttt tggctcgcaa gtatggtatg gatctttatg ccaatgaaaa
    29701 gacctggcaa gctatggaaa atagtaaata tcttggcaag gtggattctt cgcaaaagca
    29761 tatttttgaa atgggtaaaa ccaaaacctt tggagatatc gacatcgaga gttttggtgt
    29821 aagccatgat gcagtcgcac cgcagttcta tcgctttatg aaggatgata agagttttgt
    29881 ccttttgaca gatacaggtt atgtcagtga ccgtatggcg ggcattgtcg aaaatgcgga
    29941 tggctatctt atcgaggcca accatgatgt agagattttg cgatcaggtt cttacgcttg
    30001 gcgactcaaa caacgaatcc tatctgacct tggtcacctt tctaacgagg acggtgctga
    30061 agctatgatt cggacgctag gaaatcgtac taagaagatt taccttgggc atttatctaa
    30121 ggaaaataat atcaaggaac tggctcatat gaccatggtc aatcagctgg ctcaagctga
    30181 tctgggagtc ggagtagact ttaaggttta tgatacctca ccagataccg caacaccatt
    30241 gacagagata tagaaagaac gctgagaagg tgttcttttt atattgactg aacacctaaa
    30301 aagtaataca atggtgttac cattaaaaaa gggagcacaa aagatgacta ctattacatt
    30361 aaaagtttct gaagctgata aaacatttat gaaagcaatg gctaagtttg aaggagtttc
    30421 cctttcggaa cttattcgca ccaaaactct tgaagcccta gaagatgaat acgatgctcg
    30481 tgtggcagat ttagcctatc aagagtattt agaagacttg gaaaaaggag ttgaacccat
    30541 tacttgggaa gaaatgatgc atgatttagg cttgaaggat gaataatttg tataaattag
    30601 ttccaacaag acgttttatc aagcaattga aaaaattgga ccgttatacg cagaagctaa
    30661 ttacaaacta tttacaaacc aatgttttgg aaggtccaag acgacacgga aaggctttgg
    30721 ttggtaatcg cgttggtcaa tggcgctata gaattggtaa ttatcgagtt atcgtacaaa
    30781 ttgtagatga tgaattagtc gttgctactc tagaagttgg tcatcggaga gatatttatt
    30841 gaattaaagc tgagtaataa caatatagaa agtaaggaga gtaaaaattt gaagaaaaaa
    30901 tggttatttg cagattatta tgatacaaca attattttac ttgctttaat ctctgttatt
    30961 ctggtattac ttggatttgc tgagatgact gatttggaca atccgcctta tagtattatt
    31021 gatttagtaa tctggggtgt ttttgtaatt gattatagtt ggcgcttttt tattactaaa
    31081 agaaaatggc gctttattct tgaaaatatt tttgatttat tgaccattct ccctttaaat
    31141 gctattttta cagtgtttcg attaggacgt atcttccgct tagcaaggct gacaaaatta
    31201 ctgaaactga ctcgtttact tagaataatt ggacttacag gtaaactaga aagaaaaatt
    31261 agtagattct tacgaacaaa tggattgatt tatatcttgt atgttaatat ctttattgtt
    31321 ctagtaggga gttcgatttt atccgttgtt gaagaaaaat ccttctcaga tagtctttgg
    31381 tgggctcttg tgacagtaac tactgttggt tatggtgata ttgttccagt ttcccttttt
    31441 gggaaatggc tagcagtttt actgatgctt gtcggtattg gaacaatagg gatgctaaca
    31501 agtgctttga cgaacttttt tgtaaaggat aatccagatg aacagataaa acttgataaa
    31561 ctcaaagacg aattatcgag ctaaagaata ttaatagaga aacaatctga aaaaatcgaa
    31621 gaactacatt gaatgataaa agacttagtt gaaaaaatat cataaaggtg agacaaaata
    31681 aaacttgatt cgaggagaaa tcaagtaagt tttgacacaa tagaacgcat attatcaggt
    31741 ataaaaactt gatactatgc gttttataga gaaataaaat aaaatctgaa caaatcaatt
    31801 aggaatttaa agcattttat aacaacgttt tagagtaatg gggtgctatt tcaacttcaa
    31861 cctactataa tacagaaaaa aatacagaaa aaaacaactc cctgatgatt caaggagttg
    31921 tctatagtta aattagtttt tagaagcttc ttggaattct ggatttttcc atgcttcgtc
    31981 aataatagct tgcaattctt tagcagatgc ttgcattttt tgagtttctg catcgttcaa
    32041 tggaatgttt actggacgaa cgataccatg tgcaccaaca acagctggtt gaccgataaa
    32101 gacattctca actccgtatt gaccttcttg gaatactgaa agtggaagta ctgcgttttc
    32161 atcgtcaagg attgctttag tgatacgagc aagggctact gcgataccgt agtatgttgc
    32221 accttttttg ttgatgattg tgtaggctgc atcacgaaca ccttcgaaca attcaatcaa
    32281 ttcagcttct tgaacatttt gagtgtcttt aaggaattct tcaaggttta caccagcgat
    32341 gttagcgtgt gaccaaacag cgaactcaga gtcaccgtgt tcacccatga tgtaggcgtg
    32401 cactgaacga gcatccacat ccaatttttc agcaagtgct tgacggaaac gagctgagtc
    32461 aagtgaagta cctgaaccga taacgcgttc tttagggaaa ccagagaatt tccaagttga
    32521 gtaagtcaaa acgtcaactg ggttagcagc aacaaggaag atacctttga aaccagattc
    32581 aacaacttga gttacgattg atttgttgat agcaaggttt ttacctacaa ggtcaagacg
    32641 agtttcacct ggtttttgag gtgcacctgc agtgatcaca acaaggtcag cgtctgcaca
    32701 gtcagagtat tgagctgcat agattttttt aggtgaagtg aaggcaaggg cgtgactaag
    32761 gtcaagcgca tcaccaacag ctttttcatg caattgtgga atttcgataa ttccaagctc
    32821 ttgtgcaatt ccttggttaa caagtgcaaa agcgtaagat gaacctacag caccatcacc
    32881 gacaaggata acttttttgt gttgtttagt tgaagtcatt gttttaaaca tctccttaat
    32941 tttattaggg gattttccct agacaacttc attctatcac ttttaaaaaa ctttgtcacg
    33001 aatatgcctt atagttctcg atgtaaacgt tttagtggtt tagaggctga aatagatggg
    33061 aatttatggt ataatgttgt tacttactaa ttgtgaaatg aggcatttat taatgcagga
    33121 taaaaattta gtgaatgtca atctgacaaa ggagatgaag gcaagtttta tcgactacgc
    33181 catgagtgtt atcgtagcgc gagctcttcc tgatgttcga gatggcttaa aacctgttca
    33241 ccgtcgcatt ctctacggaa tgaatgaatt gggtgtgacc ccagacaaac cccataaaaa
    33301 atctgctcgt attacagggg atgtcatggg taaatatcac ccacacgggg attcctctat
    33361 ttatgaagcc atggtccgta tggctcaatg gtggagctac cgttacatgc ttgtagatgg
    33421 tcatgggaat tttggttcca tggatggaga tagtgctgcc gctcaacgtt ataccgaggc
    33481 acgtatgagc aagattgctc tggaaatgct tcgtgatatc aacaaaaata cagttgattt
    33541 cgttgataac tatgatgcca atgaacggga acccttggtc ttgccagcgc gttttccaaa
    33601 ccttttggtt aatggagcaa ctggtatcgc ggttgggatg gcaaccaata ttccacctca
    33661 taatctgggt gaaaccattg atgcagtgaa gttggtcatg gataatcctg aagtgactac
    33721 caaggacttg atggaagtct tgcctggacc agattttcca actggtgctc ttgtcatggg
    33781 gaaatcaggt atccataagg cttatgaaac aggtaaaggt tcgattgtcc tacgttctcg
    33841 tacagagatt gaaacgacta agactggtcg tgagcgtatc gttgtaacag aatttcctta
    33901 catggtcaat aaaaccaagg tgcatgagca tattgttcgc ttggttcagg aaaaacgcat
    33961 tgagggtatc acagcagtac gtgatgagtc aaaccgtgaa ggtgttcgat ttgttattga
    34021 agtcaagcgc gacgcctcag ccaatgttat tctcaataac ctcttcaaaa tgacccaaat
    34081 gcaaaccaat tttggattca atatgctcgc tatccaaaat ggtataccga aaattttgtc
    34141 tcttcgtcag attttggatg cttatattga gcaccaaaaa gaagtggttg ttcgtcgtac
    34201 acgttttgat aaggaaaaag cggaagcgcg cgctcatatc ttagaaggtc tcttgattgc
    34261 gctagaccat atcgacgaag tgattcgtat catccgtgct agtgaaacgg atgcggaagc
    34321 tcaagctgag ttgatgagca agtttaagct ttctgaacgt caaagtcaag ctatccttga
    34381 tatgcgtctt cgtcgtttga caggtttgga acgcgataag attcaatctg agtatgatga
    34441 cctcttggct ctgattgcgg atttagcaga tattcttgct aagcctgaac gtgtttctca
    34501 aattatcaaa gacgaattgg atgaagttaa acgtaaattt tctgataaac gccgtacaga
    34561 gttgatggtt ggacagatct tgagtctcga ggatgaggac ttgattgaag aatcggatgt
    34621 cttgattacc ctttctaaca gaggctacat taagcgtttg gatcaggacg agttcactgc
    34681 tcaaaaacgt gggggtcgtg gtgtccaagg aacgggagtg aaagatgatg actttgttcg
    34741 tgagttagtg tcaactagca cccatgatca tctgctcttc ttcacaaaca agggacgtgt
    34801 ctatcgtctt aaaggttatg aaattcctga gtatggtcgg actgccaaag ggctaccagt
    34861 agtcaatctc ttgaaattgg atgaagatga aagtattcag acggttatca atgttgagtc
    34921 tgatcgcagt gatgatgctt atctcttctt tacaacccgt cacggtattg tgaagagaac
    34981 tagtgttaag gagtttgcca atattcgtca aaatggtctc aaagcgctga atttaaagga
    35041 tgaagatgag ttaatcaatg tcttgttgac agaaggagat atggatatta tcattggtac
    35101 caagtttggt tatgcagttc gctttaatca atcagccgtt cgtggtatga gccgtatcgc
    35161 cactggtgtg aaaggtgtta accttcgtga aggagacaca gttgttggtg ccagcttgat
    35221 tactgatcaa gatgaggttc ttattatcac agaaaaagga tatggtaagc gtacagtcgc
    35281 tactgaatac ccaacaaaag gtcgtggtgg taagggaatg cagacagcta aaattaccga
    35341 aaaaaatggc ttgctggccg gtcttatgac tgttcaaggg gatgaggatt tgatgattat
    35401 cactgataca ggtgtcatga ttcgaaccaa tcttgccaat atttcacaaa caggacgtgc
    35461 aactatggga gttaaagtaa tgcgcctgga tcaagatgct cagatagtga ctttcacaac
    35521 ggttgcggtg gcagaaaaag aagaagttgg gacagaaaac gaaacagaag gtgaagcata
    35581 atgtctcaaa aaaataataa aaagaaaaac aagcgaaaaa atctgctgac aaatatccta
    35641 gcaggatttc tgatattact gtcactggct ttgattttta atactcaaat tcgaaatatt
    35701 ttcatagtct ggaataccaa taagtatcaa gttagccagg tatcaaaaga aaaattagaa
    35761 gaaaatcagg atacagaagg caattttgac tttgattctg tcaaagctat ctcttcggaa
    35821 gctgttctaa cttctcaatg ggatgctcaa aaattaccag ttattggggg aattgcaatt
    35881 cctgaattgg aaatgaattt gccgattttt aaaggacttg ataatgttaa tctcttctac
    35941 ggagctggta caatgaaacg cgagcaagta atgggagaag gaaattatag tctagctagt
    36001 caccatatct ttggtgttga taatgctaat aaaatgttat tttctccttt agataatgct
    36061 aaaaatggca tgaagattta tctaaccgat aaaaataaag tttatactta tgaaatacgt
    36121 gaagtcaaac gtgtgacacc ggatcgtgtt gatgaagttg atgatagaga tggggtcaat
    36181 gaaatcacat tagtaacctg tgaagacctt gctgctacag aacgtattat tgtcaaaggt
    36241 gatttgaaag aaacaaaaga ttattcacaa acatctgatg aaattctaac agctttcaat
    36301 caacca
//
LOCUS       DAVLBE010000017        34510 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.017, whole genome shotgun sequence.
ACCESSION   DAVLBE010000017 DAVLBE010000000
VERSION     DAVLBE010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34510)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34510)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34510
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.017"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            608..829
                     /locus_tag="VXB91_000886"
     CDS             608..829
                     /locus_tag="VXB91_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0470364.1"
                     /translation="MYRRLRDLREDHDLTQKQIAKILSFTNSAYAKIERGEHTLTADV
                     LVTLSNFYDVSTDYLLELTDFPDKIRFRK"
     gene            1346..1599
                     /locus_tag="VXB91_000887"
                     /pseudo
     CDS             1346..1599
                     /locus_tag="VXB91_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558195.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            1727..2956
                     /locus_tag="VXB91_000888"
     CDS             1727..2956
                     /locus_tag="VXB91_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEV0470365.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGVTIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSAASVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFAGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            2976..5672
                     /gene="ppc"
                     /locus_tag="VXB91_000889"
     CDS             2976..5672
                     /gene="ppc"
                     /locus_tag="VXB91_000889"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HEV0470366.1"
                     /translation="MSLQKLENYSNKSVVQEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAETLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATSLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMDQVVDRS
                     YDIYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYETILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     misc_binding    5755..5972
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            6085..7089
                     /locus_tag="VXB91_000890"
     CDS             6085..7089
                     /locus_tag="VXB91_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV0470367.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEAQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNITGVSDHNPAQQQ
                     VELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTSKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPESVLKEAGQVIE
                     "
     gene            7158..8024
                     /locus_tag="VXB91_000891"
     CDS             7158..8024
                     /locus_tag="VXB91_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0470368.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGRMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            8021..8779
                     /locus_tag="VXB91_000892"
     CDS             8021..8779
                     /locus_tag="VXB91_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0470369.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFERDFITILGGN
                     GAGKSTLFNTIAGTLSLTSGTIRILGEELTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLLPRRLTSYKDEFQATIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRIIQDLNQEEKAKMKISDYYQLFE"
     gene            8869..10629
                     /gene="dnaG"
                     /locus_tag="VXB91_000893"
     CDS             8869..10629
                     /gene="dnaG"
                     /locus_tag="VXB91_000893"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEV0470370.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVPFIEAVQILGQRVGIEVEKPLYSEQ
                     KPASPHQALYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPPE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDANQFVDTFHNRIMFPLTNDQGKVIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHMDRAKKSSGKASEIYLMEGFMDVIAAYRAGI
                     ESAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAATLKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENSENLQAQIEFLEKIAPLI
                     VQEKSIAAQNSYIHILADSLASFDYTQIEQIVNESRQVQRQNRMEGISRPTPITMPIT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEELERLISQKRRME"
     gene            10632..11741
                     /gene="rpoD"
                     /locus_tag="VXB91_000894"
     CDS             10632..11741
                     /gene="rpoD"
                     /locus_tag="VXB91_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HEV0470371.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            11755..12084
                     /locus_tag="VXB91_000895"
     CDS             11755..12084
                     /locus_tag="VXB91_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEV0470372.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            12199..13242
                     /gene="cpoA"
                     /locus_tag="VXB91_000896"
     CDS             12199..13242
                     /gene="cpoA"
                     /locus_tag="VXB91_000896"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HEV0470373.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVK
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREKVTYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPAALKDLKEKAKNISREYSEEHLLQIW
                     LDFYEKQAALGRK"
     gene            13258..14583
                     /locus_tag="VXB91_000897"
     CDS             13258..14583
                     /locus_tag="VXB91_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEV0470374.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGMLIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLAAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGTLYYGE
                     HDLAGAILEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFKTVLYLQQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            14614..14790
                     /locus_tag="VXB91_000898"
     CDS             14614..14790
                     /locus_tag="VXB91_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEV0470375.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVQVIWGVLTCCYGAGIVA
                     YIILWIIAPVATDY"
     gene            14849..14983
                     /locus_tag="VXB91_000899"
     CDS             14849..14983
                     /locus_tag="VXB91_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HEV0470376.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            15047..16357
                     /gene="obgE"
                     /locus_tag="VXB91_000900"
     CDS             15047..16357
                     /gene="obgE"
                     /locus_tag="VXB91_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HEV0470377.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENLEEFKKKLSENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            16367..16525
                     /locus_tag="VXB91_000901"
     CDS             16367..16525
                     /locus_tag="VXB91_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0470378.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
     gene            17612..18871
                     /locus_tag="VXB91_000902"
     CDS             17612..18871
                     /locus_tag="VXB91_000902"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEV0470379.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGASVKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
     gene            18887..19438
                     /locus_tag="VXB91_000903"
     CDS             18887..19438
                     /locus_tag="VXB91_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0470380.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLFIITHLENEASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            19431..20708
                     /locus_tag="VXB91_000904"
     CDS             19431..20708
                     /locus_tag="VXB91_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEV0470381.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIERLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFWVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            20724..21584
                     /locus_tag="VXB91_000905"
     CDS             20724..21584
                     /locus_tag="VXB91_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HEV0470382.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVVGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
     gene            21965..22767
                     /locus_tag="VXB91_000906"
                     /pseudo
     CDS             21965..22767
                     /locus_tag="VXB91_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="programmed frameshift; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            22958..25249
                     /gene="pcrA"
                     /locus_tag="VXB91_000907"
     CDS             22958..25249
                     /gene="pcrA"
                     /locus_tag="VXB91_000907"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HEV0470383.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNNLIDDVAYAAQA
                     GDMYTQIVAQCYTAYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYRADDELDEAVFVART
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGLGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYVDILNAQATLESKARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDPDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSGLPFGQFTAGAKPASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
     gene            25292..25972
                     /gene="radC"
                     /locus_tag="VXB91_000908"
     CDS             25292..25972
                     /gene="radC"
                     /locus_tag="VXB91_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HEV0470384.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQVSV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(25969..26658)
                     /locus_tag="VXB91_000909"
     CDS             complement(25969..26658)
                     /locus_tag="VXB91_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEV0470385.1"
                     /translation="MKKPVIGITGNEKAHPDDDIMMSYAAKGFVEGVKDAGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGEPKTIDSDDYHLQRDIFELTLIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(26676..27317)
                     /locus_tag="VXB91_000910"
     CDS             complement(26676..27317)
                     /locus_tag="VXB91_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HEV0470386.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            complement(27400..27615)
                     /locus_tag="VXB91_000911"
     CDS             complement(27400..27615)
                     /locus_tag="VXB91_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEV0470387.1"
                     /translation="MFELTYKDCYHVERTLKYEDHEALMLTLSGCVTLPDTLYVTSLT
                     FRGQKVYQGLVGDLYRFLSHADFLHQN"
     gene            complement(27623..27970)
                     /locus_tag="VXB91_000912"
     CDS             complement(27623..27970)
                     /locus_tag="VXB91_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HEV0470388.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKELTGAKINITDKFGLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            complement(27975..29090)
                     /locus_tag="VXB91_000913"
     CDS             complement(27975..29090)
                     /locus_tag="VXB91_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEV0470389.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFANNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLEAMY
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            complement(29100..30059)
                     /locus_tag="VXB91_000914"
     CDS             complement(29100..30059)
                     /locus_tag="VXB91_000914"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEV0470390.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            complement(30172..30741)
                     /locus_tag="VXB91_000915"
     CDS             complement(30172..30741)
                     /locus_tag="VXB91_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HEV0470391.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTPDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAENYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDITDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            30869..31540
                     /locus_tag="VXB91_000916"
     CDS             30869..31540
                     /locus_tag="VXB91_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEV0470392.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGVKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            31524..32342
                     /locus_tag="VXB91_000917"
     CDS             31524..32342
                     /locus_tag="VXB91_000917"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HEV0470393.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLEKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIAHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            32339..33235
                     /locus_tag="VXB91_000918"
     CDS             32339..33235
                     /locus_tag="VXB91_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEV0470394.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIDIPAEKGFETLEAIELPLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     YIHLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            33279..34253
                     /gene="pta"
                     /locus_tag="VXB91_000919"
     CDS             33279..34253
                     /gene="pta"
                     /locus_tag="VXB91_000919"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HEV0470395.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
BASE COUNT        10428 a         6159 c         7587 g        10336 t
ORIGIN      
        1 attatgggat ttgaattttt ccttcttcca aaactaataa aattgaaaga acaaaatcta
       61 gtttaaatgt tgctcgaaaa ttaaataatt gaatacgatt aacaatgaaa caatacaacg
      121 tgagtcatga cttcaaagta attgatttta tgattctggt ttcttacgct taattaagca
      181 agttgtattc actttatcaa attgttatta ctctaaaaag cgtctaacag ctatagagtg
      241 tctgtttgct tctctttact tttattttaa ataattcatt aaccttccgt aagtgcccaa
      301 taataaggtg tgttgaagaa gtctgagata aaatagttct cagtcacaaa aaagctatag
      361 attcccattg gtgaacagct ccctgtcaag tagacagtaa aataatataa aatcttaagc
      421 gacctgattc ctgaattcca gtggagtcag gttgtttttt aaccgtcttt cttaatattg
      481 tcttacctat aatagatatg cttatgagat atgtttaata aattaatttt agttcaaaat
      541 gtccagttag gacactttga atgatttctt agttttatat attatacttt tctcaggaga
      601 aagctagatg tacagacgtt tgagagattt gagggaagat cacgatttga cccaaaaaca
      661 aatagctaaa atactttcgt ttacaaactc agcttatgct aaaattgaac ggggtgagca
      721 tacgttaaca gcagatgtat tggtaactct ctcaaacttt tacgatgtca gtacagacta
      781 cctattggaa ttgacagatt ttcctgataa aattcgcttt agaaaataat ctcctcaatt
      841 tcatagagtg tgaaaatgag gagatttttt atttgttctt tgaaaattaa atagtccaaa
      901 atggtacttt cctcatttgt ggagcaaatt tgaatggctc gccatgataa gagcgatttt
      961 aaaaccatca ataaaataga gcgatacttt atatgccatg atacaaatga tatacaatga
     1021 tacttctgac cgttcaggct gccatcgtaa aagagcagca agtgaaattc ttatgatgac
     1081 ttcatcagtc atgccacgtt aaatgtgtga gtttgttaga gaaacgcaat taatcctcaa
     1141 aaggttcccc gaaccttttg agttccacag acgcatcacg tggagtgtgt aagcttgttg
     1201 ctaaaagcgt aaaaaccttg gaacgaaagg aataatagac ttcctgcgaa acaaaaatac
     1261 aatacaataa aactatggat gatgaagcaa gtaaacaatt aagcgatagc cgtttcaaga
     1321 gccttgtagg tgttcagcgc acgagatgtt agctgtgtta aaaacagctt atcaacgcaa
     1381 cgtaaacgcg caaaaggtgg acgaaaaacc aaattaagcc tagacgatct cctcatggta
     1441 actattcaat acatgcgaga atagcgcact tatgaacaaa ttgcggctga ttttggcatt
     1501 cacgaaagca acttaatccg tcggagccaa tgggttgaag taactcttgt tcaaaatggt
     1561 tttacgattt caaattctgc cctaattatg aaaaacagta aaattcgaag gattgtaagg
     1621 taagagtttt tttctttctg aaaaaatggt ataatagcaa tcaaaactag aaaataaaac
     1681 ggaatttgga acagatttgt ctgtatccta gtagagtggt gatgctatga agattagtaa
     1741 gaggcactta ttaaattatt ccatcttgat tccctacttg cttttatcta ttttgggctt
     1801 gattgtggtc tattcgacca ccagtgctat tttaattgaa gaaggcaaga gcgccttgca
     1861 gttggttcga aaccaaggaa tcttttggat tgttagtttg atactgattg ccttaattta
     1921 taaattgaga ctagattttt tgagaaatga gcgactaatc attttagtta tattaataga
     1981 aatgctttta ttgttcttgg ctcgttttat tggtatttcc gtaaacgggg catacggttg
     2041 gatttcggtt gcaggagtaa ctattcagcc agctgagtac ttaaaaatca ttattatttg
     2101 gtatttagct caccgattct ccaaacagca agaagaaata gctacttatg attttcaagt
     2161 tttgactcaa aatcaatggc ttccccgtgc ttttaatgat tggcgattcg ttctcctagt
     2221 tctgattgga agtttgggaa ttttccctga tttaggaaat gcgactattt tagtcttggt
     2281 ttccttgatt atgtatacag ttagtggaat cgcttatcgc tggttttcaa ccattctggc
     2341 gctcgtatct gccgcttctg tctttgtctt gaccactatc agcctaatcg gtgttgagac
     2401 cttttcaaaa attccagtat ttggctatgt agccaagcgc tttagtgcct tttttaatcc
     2461 ttttgccgat cgtgctgatg caggtcacca gttagctaat tcttattttg ccatggtcaa
     2521 tggtggttgg tttggtctag gtcttggaaa ctcgattgaa aaacgaggtt atttgccaga
     2581 agctcataca gactttgtct tttctatcgt gattgaagaa tttggctttg ctggtgccag
     2641 tcttatttta gctctcttgt ttttcatgat tttgcggatt atcttggtcg gtattcgagc
     2701 ggagaatcct ttcaatgcca tggttgcact cggtgtcgga gggatgatgt tggttcaggt
     2761 atttgtcaat atcggaggga tttcgggctt gattccatct acaggagtaa ccttcccctt
     2821 cttatcccag ggtggaaata gtcttctagt cttatcagtg gcagtagcct ttgtcttaaa
     2881 tattgatgcc agtgaaaaac gcgctaagtt gtaccgagaa ttggaaaatc aaccaatgaa
     2941 ccttctgttg aagtaggata aagaaaggat agtttatgtc tcttcaaaaa ttagaaaatt
     3001 atagtaataa aagtgttgtg caagaagaag tcttgattct aacagaatta ctggaagata
     3061 ttactaaaaa tatgcttgcc ccagagacct ttgaaaaaat aatacagttg aaagaattat
     3121 caacgcagga agattatcaa ggtctaaacc gtctagtgac tagcttatca aatgatgaaa
     3181 tggtctatat ttcacgctat ttctctatct tacctctttt gatcaatatt tcagaggatg
     3241 tggatttagc ttatgaaatc aatcatcaaa ataatattga tcaggactat ttaggtaaat
     3301 tatctacaac gattaaattg gtagcagaaa aggaaaatgc cgttgagatc ctagaacact
     3361 tgaatgttgt ccctgttttg acagcccatc caacacaagt gcaacgcaaa agtatgttgg
     3421 atttaacaaa tcatattcat agtcttttgc gtaaataccg tgatgttaag ttggggttga
     3481 tcaataaaga taaatggtac aatgatttgc gtcgttacat cgaaattatc atgcagacag
     3541 acatgattcg tgagaaaaaa ttaaaagtga ctaacgaaat cacgaatgct atggaatatt
     3601 ataacagctc ctttttgaaa gctgtacctc atttgacgac ggagtataag cgcttagcgc
     3661 aagcgcatgg tctgaattta aaacaggcta aaccaatcac catgggtatg tggataggtg
     3721 gtgaccgtga tggaaatcca tttgttacag cagagacctt gaagcagtct gcactcactc
     3781 aatgtgaagt catcatgaac tactatgata aaaagattta ccaactttat cgtgaatttt
     3841 ctctttcaac tagcattgtc aacgtcagca agcaagtcag agaaatggct cgtcaatcca
     3901 aggataactc gatttaccgc gaaaaagagc tttaccgtcg tgccttgttt gatattcaat
     3961 caaaaattca ggcaactaaa acctatctga ttgaggatga agaagttggg actcgttatg
     4021 aaaccgccaa tgatttctac aaggatttga ttgccattcg agattctcta ctagaaaata
     4081 agggtgagtc cttgatttca ggtgattttg tggaattatt gcaggcagta gagatatttg
     4141 gtttttacct agcatcaatt gatatgcgac aagactctag cgtctatgaa gcctgtgtgg
     4201 cagaactctt gaaatcagca ggaattcatt ctcgttatag cgagttgagc gaagaagaaa
     4261 agtgtgacct tctcttgaaa gaattagaag aagatccccg aattctttct gcgactcacg
     4321 cagaaaaatc agaattatta gcaaaagaat tagctatttt taagacggct cgtgttttga
     4381 aagataagtt gggagatgat gtcatccgtc agaccatcat ttcacatgca accagccttt
     4441 ctgatatgct agaattagct attctgttaa aagaagtagg actggtggat acggaaaggg
     4501 cgcgtgttca gattgttccc ctttttgaaa caattgaaga cttggatcat tcagaagaaa
     4561 caatgagaaa atatctttct cttagccttg ccaaaaaatg gattgactca cgaaataact
     4621 accaagaaat catgcttggc tactctgaca gtaataaaga tggcggttac ttgtcatcat
     4681 gttggaccct ctacaaggct caacaacaat tgactgctat tggagatgaa tttggcgtta
     4741 aggttacctt cttccatggt cgtggtggta ctgtcggtcg tggtggtggg ccaacctatg
     4801 aagccattac atctcaaccg ctcaagtcta tcaaggatcg tatccgcttg acggagcagg
     4861 gtgaagtaat tgggaataaa tacggtaaca aagacgccgc ttactataac cttgaaatgc
     4921 tagtatcggc agctattaac cgtatgatta ctcagaagaa gagcgatacc aataccccaa
     4981 atcgttatga agccattatg gatcaagtag tggaccgtag ttacgatatc taccgtgatt
     5041 tggtctttgg taatgagcat ttctatgatt atttcttcga gtcaagtcca atcaaggcta
     5101 tttcaagttt taatattggt tctcgtccag ccgctcgtaa gactattact gaaatcggtg
     5161 gtttgcgtgc catcccttgg gtattctcat ggtcacagag tcgtgttatg ttccctggat
     5221 ggtacggggt tggttcaagc ttcaaggaat ttatcaataa aaatccagag aatattgcta
     5281 tcttacgaga tatgtaccaa aattggcctt tcttccaatc gcttctttca aatgttgata
     5341 tggttttgtc aaaatcaaat atgaatattg cttttgaata tgctaaactt tgtgaagacg
     5401 agcaagttaa ggccatctat gagactattt taaatgaatg gcaagttact aagaacgtta
     5461 tcttggctat tgaaggacat gacgaactct tagctgacaa tccatatcta aaagctagtc
     5521 tggattaccg tatgccttac tttaatattc tcaactatat tcagttagag ttgattaaac
     5581 gccaacgtcg tggagaattg tccagtgatc aagaacgatt gattcatatc accatcaacg
     5641 gaattgcgac aggattgcgt aattcaggtt gataattttc aagagtgaat gctaaaagtg
     5701 aatatcaaaa aaattctaat agactattga caagtagttt aaaaatgata taatttaacc
     5761 attcagaaaa gtaatcatac aaacttttta gagagtctgt ggtagctgaa aacagataag
     5821 tggcgatgat gaaaattggg ctgaatgcta tttagaattt gaaattataa aaattcggta
     5881 agcacacctt acagtgcatc tcgttattgc gagactgagc gatagggaaa ttccctataa
     5941 ttgaggtggt accgcgcatc gacgtcctca cacaagtttt ttgtgtgagg atttttttga
     6001 tggaggttag tatggaaaga aaacgatggc gtcgcttgtt tagataagtg aaatatgtta
     6061 aaggaaataa aaaggagaaa cagaatgaaa aataaacgtt taattggaat tattgctgca
     6121 ttagcagtct tagtagcagg aagcttgatt tattcttcaa tgaataaatc agaagctcag
     6181 aataataagg atgagaagaa aataactaag attggtgtgc ttcaatttgt gagccatcca
     6241 tcccttgatt tgatttataa agggatccaa gatggacttg cagaagaagg atataaagat
     6301 gatcaagtta aaattgattt tatgaactca gaaggtgacc aaagtaaggt tgcgacaatg
     6361 agtaaacaat tggttgcaaa tgggaatgac cttgtggttg gtatcgcaac accagcagcc
     6421 caagggttgg ctagtgcaac aaaagaccta ccggttatca tggccgctat tacagaccca
     6481 attggtgcta acttggttaa agatttgaaa aaaccaggtg gcaacattac aggggtatct
     6541 gaccacaatc cagctcaaca acaagttgaa ctcatcaagg ctctgacacc gaatgtgaaa
     6601 acaatcggag ctctttactc aagtagcgaa gacaattcaa aaacacaggt cgaagaattt
     6661 aaggcttatg ctgaaaaagc aggtctgaca gtggaaacat ttgcagttcc ttcaacaaat
     6721 gaaattgcct caactgtcac tgttatgact agcaaggtag atgctatttg ggttccaatt
     6781 gataacacca ttgcatcagg atttccaacg gttgtctcta gcaatcaaag ttctaagaaa
     6841 ccaatttatc ccagtgcgac agctatggta gaagtaggtg gtttggcatc agttgtaatt
     6901 gaccaacatg accttggtgt ggcaacaggt aaaatgattg tgcaagtctt gaaaggtgca
     6961 aaaccagccg ataccccagt caatgtcttt tcaactggta agtcagtcat caataaaaaa
     7021 atagcacaag aactaggtat tactattcct gagtctgttc tcaaagaagc aggacaagtc
     7081 atcgaataaa taaggtaggg aggaggagac tcttcccatt ttttaaaaag atgaatatag
     7141 aaaggattaa ataaaatatg attgtttcca ttatttctca aggatttgtc tgggctattc
     7201 taggtctggg aatctttatg acatttagga ttttaaactt tccagatatg acgacagaag
     7261 gttccttccc tcttggggga gctgttgctg tcactttgat aaccaaaggc gtgaacccat
     7321 ttttagcgac acttgttgct gtaggagcag gttgtttggc tggaatggca gcaggccttc
     7381 tttatacaaa agggaagatc ccaaccttgc tatcagggat tttggtgatg acttcttgtc
     7441 actcaatcat gctcttgatt atgggacgtg cgaatttagg cctgcttgga accaagcaaa
     7501 ttcaggatgt tttgcctttt gattcggatt tgaatcaact cttgacaggt ctcatctttg
     7561 tgagtattgt tattgctctc atgctctttt tcttggacac taaactcgga caagcctata
     7621 ttgctacagg ggataatcct gatatggcta gaagtttcgg gattcatact ggacgcatgg
     7681 agctcatggg cttggtctta tcaaatggtg tgattgccct tgcaggtgcc ctcattgctc
     7741 agcaagaagg ttatgccgat gtgtctcgag ggatcggggt tatcgttgtg gggcttgcaa
     7801 gtttgattat tggagaagtt attttcaaga gtttgagctt ggcagagcgt ttggttacta
     7861 tcgttgtagg ttctatcgct tatcaatttt tagtgtgggc agttatcgca cttggcttta
     7921 atacaagtta ccttcgttta tacagtgcct tgattttagc agtctgcctc atgattccaa
     7981 catttaagca aacaatcttg aaaggagcca agttaagcaa atgacagcaa ttgtagaatt
     8041 aaaaaatgca accaaaatcg ttaaaaatgg ctttgatgaa gaaaagatta ttttaaatga
     8101 tgtttcctta gaaatttttg aacgggactt tatcacgatt ttgggcggaa atggtgctgg
     8161 aaaatcaacc ctctttaaca ctatagcagg gaccttatca ctaactagtg gaactatccg
     8221 tattttaggt gaagaactca ctaagttttc acccgagaag cgtgccaagt acctgtctcg
     8281 tgtcttccaa gatccaaaga tggggacagc tccccgtatg acggtcgctg aaaatctttt
     8341 aatcgccaag tttcgtggtg aaaagcgtgg attgttacca cgacgcttga ctagctataa
     8401 ggatgaattt caggcaacca ttgaaaaagt aggaaatggt cttgagaaac acttgaatac
     8461 accgattgag ttcttatcag gtggacaaag acaggctttg agtctcttga tggcaacctt
     8521 gaagcgacct gaattactcc tgttagatga gcatactgct gccctggatc caaagactag
     8581 tgttgctttg atggaattga cagatgaatt tgttaagaaa gatcagctaa cagcccttat
     8641 gattactcat catatggaag atgctctcaa atacggcaat cgcttgattg tcatgaaaga
     8701 aggacggatt atccaagatt taaaccaaga agaaaaagca aaaatgaaaa tctctgatta
     8761 ttatcaactc tttgaataaa gtagggaaaa tgagtgaaat ggtttacttt ttttctgaaa
     8821 taaagtatac tatataaagt aaactatgat aacatggagg tattgtgtat ggttgacaaa
     8881 caagtcattg aagaaatcaa aaacaatgcc aacattgtgg aagtcatagg agatgtgatt
     8941 tctttacaaa aggcaggacg gaactatcta gggctctgtc cttttcatgg tgaaaaaaca
     9001 ccttctttca acgttgtaga ggataagcag ttttatcact gtttcggttg tggtcgctca
     9061 ggtgatgtct ttaagttcat cgaggagtac caaggggttc cctttataga ggcagtccaa
     9121 atcttaggtc agcgtgttgg aattgaggtt gaaaaaccgc tttatagtga gcagaagcca
     9181 gcctcacctc accaagctct ttatgatatg cacgaagatg cagccaaatt ttaccatgcg
     9241 attctcatga caacgactat gggcgaagag gccagaaatt acctttatca gcggggtttg
     9301 acagatgaag tgcttaaaca tttttggatt ggtttagcac ctccagaacg aaactatctc
     9361 tatcaacgtt tgtctgatca gtatcgtgaa gaggatttac tggattcagg cctgttttat
     9421 ctctcggatg ccaatcaatt tgtagacacc tttcacaatc gcattatgtt tcccctgaca
     9481 aatgaccaag gaaaggtcat tgccttctca ggtcgtatct ggcaaaaaac ggattcacaa
     9541 acttctaagt ataaaaacag ccgatcgact gcaattttta acaaaagtta cgaattatat
     9601 catatggata gggcaaaaaa atcttctgga aaagctagtg agatttactt gatggaagga
     9661 ttcatggatg ttattgcagc ctatcgggct ggaatcgaaa gtgctgtggc gtcgatggga
     9721 acggccttga gtcgagagca tgttgagcat ctgaaaaggt taaccaagaa attggttctt
     9781 gtttacgatg gagataaggc tgggcaagcc gcgacattga aagcattgga tgaaattggt
     9841 gatatgcctg tgcaaatcgt cagcatgcct gataacttgg atcctgatga gtatctacaa
     9901 aaaaatggtc cagaagactt ggcctatcta ttaacgaaaa ctcgtattag tccgattgag
     9961 ttctacattc atcagtacaa acctgaaaac agtgaaaatc tgcaggctca gattgagttt
    10021 cttgaaaaaa tagctccctt gattgttcaa gaaaagtcca tcgctgctca aaacagctat
    10081 attcatattt tagctgacag tctggcgtcc tttgattata cccagattga gcagattgtt
    10141 aatgagagtc gtcaggtgca aaggcagaat cgcatggaag gaatttccag accgacgcca
    10201 atcaccatgc caatcaccaa gcagttatcg gctattatga gggcagaagc ccatctactc
    10261 tatcggatga tggaatcccc tcttgttttg aacgattacc gtttgcgaga agactttgca
    10321 tttgctacac ctgaatttca ggtcttatat gacttgcttg gccagtatgg aaatcttcct
    10381 ccagaagttt tagcagagca gacagaggaa gttgaaagag cttggtacca agttttagct
    10441 caggatttgc ctgctgaaat atcgccgcag gaacttagtg aagtagagat gactcgaaac
    10501 aaggctctct tgaatcagga caatatgaga atcaaaaaga aggtgcagga agctagccat
    10561 gtaggagata cagatacagc cctagaagaa ttggaacgtt taatttccca aaagagaaga
    10621 atggagtaat aatggcaaca aaacaaaaag aagtaacaac atttgacgta caggtagcag
    10681 aatttatccg taatcataag caaaaaggga cagcaacaga tgatgaaatc aatgcaagtc
    10741 tggttattcc ttttaccttg gacgctgatg ggattgaaga tctcttgcaa cggattcagg
    10801 atgcaggaat ttctatcaca gataacgaag gaaatccaag tgcgcgtgtt cttagcaatg
    10861 aagaagaacc agaactcagc gatgaggact tgattgggtc aacttctgct aaggtcaatg
    10921 accctgtccg tatgtacttg aaagaaatag gggtcgttcc tctcttgacc aatgaagagg
    10981 agaaagagtt ggcactggct gttgaagctg gtgatatcga agccaaacaa cgtcttgcgg
    11041 aagccaatct tcgtttggtt gtttccattg ccaaacgcta tgtcggtcgt ggcatgcagt
    11101 tccttgactt gattcaagaa ggaaatatgg gcttgatgaa ggcggttgac aagtttgact
    11161 attctaaagg gttcaagttt tcaacttatg caacttggtg gattcgtcag gctatcactc
    11221 gtgctattgc ggaccaagct cgtaccatcc gtatcccagt tcacatggtt gaaactatca
    11281 ataaattggt tcgtgaacag cggaatctcc ttcaagaatt ggggcaagat ccgacaccag
    11341 aacagattgc tgaacgaatg gatatgacac ctgataaggt tcgtgaaatc ttgaagattg
    11401 cccaagaacc agtatctctt gaaactccta tcggtgaaga ggacgatagc caccttggag
    11461 actttatcga agatgaagtg attgaaaatc cagtggatta tacgactcgt atcgtcttgc
    11521 gtgagcaatt ggatgaaatc ttagatactc ttacagaccg tgaagaaaat gttctgcgtc
    11581 tacgttttgg actagatgat ggaaaaatgc gcacacttga agatgtgggg aaagtcttta
    11641 acgtaactcg tgagcgtatc cgtcagattg aagcaaaggc tttgagaaaa ctacgccaac
    11701 caagtcgtag caaaccgctt cgtgatttta ttgaagacta agagtgagga aaatatggct
    11761 tatacagaag agcaaattga aaacatcaaa acacggattt taacagcctt ggaagaagtc
    11821 atcgaccctg agttgggaat cgatattgtc aatcttggtt tgatctatga gattcgtttt
    11881 gacggtgaca cagggcaaac agagattgac atgactttga caactatggg ttgtccctta
    11941 gcagaccttt tgacagacca gatttatgat gctatgatag aggttccaga agtaacggat
    12001 actgaggtta aattagtctg gtatccagcc tggacagttg aaaaaatgag tcgctatgcc
    12061 cgcattgccc taggcattaa gtaaacatat aaaagcatgt gagagactgt tggaaaagcg
    12121 aggaaatttc ccctcttttc ctctagtctc tcctttcttt tgctgatttt attcaaagaa
    12181 aatgatataa tagtagttat ggagaaaaag aaattacgca tcaatatgtt gagttcaagt
    12241 gagaaagtag caggacaggg agtttcaggt gcttaccgtg aattagttcg tcttcttcac
    12301 cgtgctgcca aggaccaatt gattgttaca gaaaatcttc caatcgaggc agatgtgact
    12361 cactttcata cgattgattt tccctattat ttatcaacct tccaaaagaa acgctcaggg
    12421 agaaagattg gctatgtgca tttcttgcca gctacacttg agggaagttt gaaaattcca
    12481 tttttcttaa agggaattgt gaaacgctat gtattttctt tttacaaccg gatggagcac
    12541 ttggttgtgg tcaatcctat gtttattgag gatttggtag cagctggtat tccacgtgaa
    12601 aaagtgacct atattcctaa ctttgtcaac aaggaaaaat ggcatcctct accacaagaa
    12661 gaggtagtca gactgcgcac agatcttggt cttagtgaca atcagtttat cgtagtaggt
    12721 gctgggcaag ttcagaaacg taaagggatt gatgacttta tccgtctggc tgaggaattg
    12781 cctcagatta cctttatctg ggctggtggc ttctcttttg gtggtatgac agatggttat
    12841 gaacactata agaaaattat ggaaaatccc cctaaaaatt tgatttttcc aggcattgta
    12901 tcgccagagc ggatgcgcga attgtatgct ctagcggatc ttttcttgtt gcctagttac
    12961 aatgagctct ttcctatgac tattttagaa gctgcgagtt gtgaggctcc tattatgttg
    13021 cgtgatttag atctctataa ggtaattttg gagggaaatt atcgggcgac agcgggtaga
    13081 gaagagatga aagaggctat tttggaatat caagcaaatc ctgctgcctt aaaagatctc
    13141 aaagaaaagg ctaagaatat ttccagagag tattctgaag agcatctgtt acaaatctgg
    13201 ttggactttt atgagaaaca agccgcttta gggagaaagt aaaaagtgag gtaatctatg
    13261 cgaattggtt tatttacaga tacctatttt cctcaggttt ctggtgttgc gaccagtatt
    13321 cgaaccttga aaacagaact tgaaaagcag ggacatgctg tttttatctt tacgacgaca
    13381 gataaggatg tcaatcgcta cgaagattgg caaattatcc gcattccaag tgttcctttc
    13441 tttgctttta aggatcgtcg ctttgcctac cgaggtttta gcaaggcact tgaaattgct
    13501 aaacagtatc agctagatat tatccatact cagacagaat tttctcttgg cctgttgggg
    13561 atttggattg cgcgtgaatt gaaaattcca gtcatccata cctatcacac ccagtatgaa
    13621 gactatgtcc attatattgc taaggggatg ttgatccggc cgagtatggt caagtatctg
    13681 gttagaggtt tcctgcatga tgtggatggg gttatttgtc ctagtgagat tgtccgtgac
    13741 ttgctatctg attataaggt caaggttgaa aaacgggtca ttcctactgg gattgaatta
    13801 gccaagtttg agcgtccgga aatcaagcag gaaaatttga aagaactgcg tagtaaacta
    13861 gggattcaag atggtgaaaa gacgttgctt agtctttcga gaatctccta tgaaaaaaat
    13921 attcaagcag ttttagcagc ctttgctgat gttctgaaag aggaagacaa ggttaaactg
    13981 gtagtagctg gggatggccc ttatctgaat gacctcaaag agcaagctca gaacctagag
    14041 attcaagact cagtcatctt tacagggatg attgctccta gtgagacggc tctttactat
    14101 aaagcggcgg atttcttcat ttcggcatcg acaagcgaaa cgcaaggttt gacctacttg
    14161 gaaagcttag ccagtggaac acctgtcatt gctcacggaa atccttattt gaacaacctc
    14221 atcagtgata aaatgtttgg aaccttgtac tatggagaac atgatttggc tggtgctatt
    14281 ttggaagccc tgattgcaac accagacatg aacgagcata ccttatcaga gaaattgtat
    14341 gagatttcag ctgagaactt tgggaaacga gtgcatgagt tttatctgga tgccattatt
    14401 tcaaataact tccagaaaga tttggctaaa gatgatacgg tcagtcagcg tatctttaag
    14461 acagttttgt atcttcagca acaggtggtt gctgtacctg taaaaggatc tagacgcatg
    14521 ttgaaggctt caaaaacaca gttgatcagt atgagagact attggaaaga ccatgaagaa
    14581 tagaaagagg aacagctatg aaaaaaacaa ttaatgagaa gcggtcgtga taaaaagatt
    14641 gcgggtgttt gtgctggggt ggcccattat ctggatatgg atccgactat cgttcaagtc
    14701 atttggggtg ttcttacttg ctgttacgga gctggaattg tagcttacat tattttatgg
    14761 attatcgcac cagtagcaac tgactattga aaactagctc aattcatgct aagataatag
    14821 aaaatagaat gtaacgaagg agagaaaaat ggcatttgga gataatggaa atcgtaaaaa
    14881 aactatgttt gagaaaataa ccttgtttat cgtgattatc atgctagtag caagtttatt
    14941 gggaattttt gcaactgcaa ttggtgccct cagtaatcta taaaatagat tcaagaaaat
    15001 ttagtgactg ggatttccca gccctttttt aaagtgagaa gaaataatga gtatgttttt
    15061 agatacagct aagattaagg tcaaggctgg taatggtggc gatggtatgg ttgcctttcg
    15121 tcgtgaaaaa tatgtcccta atggaggccc ttggggtggt gatggtggtc gtggaggcaa
    15181 tgtggtcttc gttgtagacg aaggactacg taccttgatg gatttccgct acaatcgtca
    15241 tttcaaggct gattctggtg aaaaagggat gaccaaaggg atgcatggtc gtggtgctga
    15301 ggaccttaga gttcgagtac cacaaggtac gactgttcgt gatgcggaga ctggcaaggt
    15361 tttaacagat ttgattgaac atgggcaaga atttatcgtt gcccacggtg gtcgtggtgg
    15421 acgtggaaat attcgtttcg cgacaccaaa aaatcctgca ccggaaatct ctgaaaatgg
    15481 agaaccaggt caggaacgtg agttacaatt ggaactaaaa atcttggcag atgtcggttt
    15541 agtaggattc ccatctgtag ggaagtcaac acttttaagt gttattacct cagctaagcc
    15601 taaaattggt gcctaccact ttaccactat tgtaccaaat ttaggtatgg ttcgcaccca
    15661 atcaggtgaa tcctttgcag tagccgactt gccaggtttg attgaagggg ctagtcaagg
    15721 tgttggtttg ggaactcagt tcctccgtca catcgagcgt acacgtgtta tccttcacat
    15781 cattgatatg tcagctagcg aaggccgtga tccatatgag gattacctag ctatcaataa
    15841 agagctggag tcttacaatc ttcgcctcat ggagcgtcca cagattattg tagctaataa
    15901 gatggacatg cctgagagtc aggaaaatct tgaagaattt aagaaaaaat tgtctgaaaa
    15961 ttatgatgaa tttgaagagt taccagctat cttcccaatt tctggattga ccaagcaagg
    16021 tctggcaaca cttttagatg ctacagctga attgttagac aagacaccag aatttttgct
    16081 ctacgacgag tccgatatgg aagaagaagc ttactatgga tttgacgaag aagaaaaagc
    16141 ctttgaaatt agtcgtgatg acgatgcgac atgggtactt tctggtgaaa aactcatgaa
    16201 actctttaat atgaccaact ttgatcgtga tgaatctgtc atgaaatttg cccgtcagct
    16261 tcgtggtatg ggggttgatg aagcccttcg tgcgcgtgga gctaaagatg gggatttggt
    16321 ccgcattggt aaatttgagt ttgaatttgt agactaggag actggtatgg gagataaacc
    16381 gatatctttc cgagatgcgg atggtaattt tgtttccgcc gcagacgttt ggaatgaaaa
    16441 gaaattggaa gaactattta atcgtctcaa tccaaatcgt gccttgagat tggcacgaac
    16501 taaaaaggaa aatccatctc agtaaagaag ctaaaaaatc ccgtgcctca tcagacacgg
    16561 gattttgtgg tacgacaggc atgtatagca aactgaatct ggaatagcac agcatatctt
    16621 ctaaaatatt gctataaatt gatttgaatt tcaaaattaa attgttttat tcttatttca
    16681 atttgttata gtatatctga tgtcaaagtt ctcggcgagt caaatagtga ttcccaagcc
    16741 tgactatcgt gaggtagcgg attaaaatgg tctggggata gaccgtttta agtctgatgc
    16801 tggaaataag aattgtcaga agaagggata gcgaaatcgt ggctctacga acaggaacgt
    16861 gataataagg cgtatatagc gaataagagg gcctcaaact ctaaagtcca aaaaggtagt
    16921 cgtaacctat atgcgtaaat catgagagta attgaattcg tactaagatt ttctattttt
    16981 actgtaacct tttaacgtcc tcatatcttg tatacacgag gaaagatgta cgacttatcc
    17041 cgtgaggtct atcactataa agagaaaacg acagatagaa gtgatcctga gtcacggtta
    17101 tctttaaaat agattgtctg ataggatgct agcctgaaaa cgtcttgttc atgaaatata
    17161 ggacggtatg tataaaacgc ttctgtgaac tgagagaagg gggagaagtt cttgctaaaa
    17221 tttagttgaa cagccgtatt ccgatactta gataagagat ctagtcttag ctcctactca
    17281 gtttcagggg ataaaaaagg ggcaatagcg attcgagaaa gattatactc ttcgaaaatc
    17341 tcttcaaatc acgtcaatat cgccttgccg tatgtgtagg atactaacta cgtcagttcc
    17401 atctacaatc tcaaaacagt gttttgagca acctgcggct agtttcctag tttgatcttt
    17461 gatttttatt gagtattagt aattcagtta ctaactcgtc aactctgatt tatccaataa
    17521 aattgaaaag gatggaaaaa aggataaatt tatgatatac tttattttga agaccttatt
    17581 agaaatcttg aaagagtatt gaaaacttag aatgagaaaa attgttatca atggtggatt
    17641 accactgcaa ggtgaaatta ctattagtgg tgctaaaaat agtgttgtgg ccttaattcc
    17701 agctattata ttggctgatg atgtggtgac tttggattgt gttccagata tttcggatgt
    17761 agccagtctt gtcgaaatca tggaattaat gggagctact gttaagcgtt atgacgatgt
    17821 cttggagatt gatccaagag gtgttcaaaa tattccaatg ccttatggta aaattaacag
    17881 tcttcgtgca tcttactatt tttatgggag cctcttaggc cgttttggtg aagcgacagt
    17941 tggtctaccg ggaggatgtg atcttggtcc tcgtccgatt gacttacacc ttaaggcgtt
    18001 tgaagctatg ggtgccactg ctagctacga gggagataac atgaagttat ctgctaaaga
    18061 tacaggactt catggtgcaa gtatttacat ggatacggtt agtgtgggag caacgattaa
    18121 tacgatgatt gctgcggtta aagcaaatgg tcgtactatt attgaaaatg cagcccgtga
    18181 acctgagatt attgatgtag ctactctctt gaataatatg ggtgcccata tccgtggggc
    18241 aggaactaat atcatcatta ttgatggtgt tgaaagatta catgggacac gtcatcaggt
    18301 gattccagac cgcattgaag ctggaacata tatatcttta gctgctgcag ttggtaaagg
    18361 aattcgtata aataatgttc tttacgaaca cctggaaggg tttattgcta agttggaaga
    18421 aatgggagtg agaatgactg tatctgaaga cagcattttt gtcgaggaac agtctaattt
    18481 gaaagcaatc aatattaaga cagctcctta cccaggcttt gcaactgatt tgcaacaacc
    18541 gcttacccct cttttactaa gagcgaatgg tcgtggtaca attgtcgata cgatttacga
    18601 aaaacgtgta aatcatgttt ttgaactagc aaagatggat gcggatattt cgacaacaaa
    18661 tggtcatatt ttgtacacgg gtggacgtga tttacgtggg gccagtgtta aagcgaccga
    18721 cttaagagct ggggctgcac tagtcattgc tgggcttatg gctgaaggta aaactgaaat
    18781 taccaatatc gagtttatct tacgtggtta ttctgatatt atcgaaaaat tacgtaattt
    18841 aggagcggat attagacttg ttgaggatta aaccgtagag gtgtttatga atatttggac
    18901 caaattagca atgttttctt tttttgaaac ggatcgcttg tatttgcgtc ctttcttttt
    18961 tagtgatagt caggacttcc gcgagatagc ttcaaatcca gaaaatcttc aatttatttt
    19021 cccaacgcag gcaagtctgg aagaaagtca atatgcactg gccaattact ttatgaagtc
    19081 ccctttggga gtgtgggcaa tttgtgacca gaaaaatcaa caaatgattg gttctattaa
    19141 atttgagaag ttagatgaaa tcaaaaaaga agctgagctt ggctattttt tgagaaaaga
    19201 tgcttggtcg caaggattta tgacagaggt tgttagaaaa atttgtcagc tttcttttga
    19261 ggaatttggc ttaaaacaat tatttatcat tacccacctt gaaaatgaag ctagccaaag
    19321 agttgctctt aagtctggat ttagtttgtt ccgtcagttt aagggaagtg atcgttacac
    19381 aagaaaaatg cgggattatc ttgaatttcg gtatgtaaaa ggagagttca atgagtaagc
    19441 atcaggaaat tctaagctat ttggaggaat taccagtagg taaaagggtc agtgttcgta
    19501 gcatttcgaa tcatctagga gttagtgatg gaacagccta tcgagctatt aaagaagctg
    19561 aaaaccgtgg aattgtggag acccgtccta gaagtggaac aattcgtgtt aaatcccaga
    19621 aagttgctat agagagatta acgtttgctg aaattgcaga agtgacttct tctgaggttc
    19681 tggctgggca agaaggttta gagagagagt ttagtaagtt ttcaattggt gccatgactg
    19741 aacaaaatat cttgtcttac cttcatgatg gggggctctt gattgtcgga gaccgaaccc
    19801 gtattcagtt gctagccttg gaaaatgaaa atgcagttct ggttacaggg ggatttcagg
    19861 ttcatgatga tgtgcttaaa ctggccaatc aaaaagggat tcctgttcta agaagtaagc
    19921 atgatacctt taccgtcgcg accatgatca ataaagcctt gtcaaatgtc caaatcaaga
    19981 ctgatattct gacagttgag aaactttatc gccctagtca tgagtatggt tttctgagag
    20041 agacagatac agttaaagat tatttggact tggttcgtaa gaatcgtagc agccgtttcc
    20101 ctgttatcaa tcaacatcag gtcgttgttg gtgttgtaac catgagagac gctggtgata
    20161 aatcaccaag cacgacaatt gataaggtta tgtctcgtag tctattttgg gttggattat
    20221 cgacaaatat tgccaatgtg agtcaacgga tgatcgcaga agactttgaa atggtaccag
    20281 ttgttcgaag caatcaaact ttgcttggcg ttgtgacgcg acgagatgtc atggagaaga
    20341 tgagccgttc ccaagtttcg gctctaccaa ctttttctga gcagattgga caaaagctct
    20401 cttatcacca tgatgaagta gtcattacag tggaaccctt tatgctagaa aaaaatggag
    20461 ttttggctaa tggtgtattg gcagaaattc tgacccacat gacccaagat ttagttgtta
    20521 atagtggtcg caatctcatt atcgagcaga tgctgatcta ctttttgcag gctgttcaga
    20581 tagatgatat attgcgcatt caggcacgga ttattcatca tacgagacgg tcagctataa
    20641 ttgattacga tatttatcat ggtcaccaga ttgtttcaaa agcaaatgtg actgttaaaa
    20701 ttaattagaa actaggagaa aagatgataa cattaaaatc agctcgtgaa atcgaagcta
    20761 tggacaaggc tggtgatttt ctagcaagta ttcatatagg cttacgtgat ttgattaagc
    20821 caggcgtaga tatgtgggaa gttgaagaat atgtccgccg tcgttgtaaa gaagaaaatt
    20881 tccttccact tcagattggg gttgacggtg ccatgatgga ctatccttat gctacctgtt
    20941 gctctcttaa cgatgaagtg gctcacgctt tccctcgtca ttatatcttg aaagatggtg
    21001 atttgctcaa agttgatatg gttttgggag gtcccattgc taaatccgac ctgaatgtct
    21061 caaaattaaa cttcaacaat gttgaacaaa tgaaaaaata cactcagagc tattctggtg
    21121 gtttagcaga ctcatgttgg gcttatgctg ttggtacacc gtccgaagaa gtcaaaaact
    21181 tgatggatgt aaccaaagaa gctatgtaca agggtattga gcaagctgtt gttggaaatc
    21241 gtatcggtga tatcggtgcg gctattcaag aatacgctga aagtcgtggt tacggtgtag
    21301 tgcgtgattt ggttggtcat ggtgttggcc caactatgca cgaagaacca atggttccta
    21361 actatggtat tgcaggtcgt ggactccgtc ttcgtgaagg aatggtctta accattgaac
    21421 caatgatcaa tacaggcgat tgggaaattg atacagatat gaaaactggt tgggcgcata
    21481 agaccattga cggtggattg tcatgtcagt atgaacacca atttgtcatt acgaaagatg
    21541 gacctgttat cttgactagc caaggtgaag aaggaactta ttaataaaaa gtgaaaagac
    21601 tactggaagt ttattttgat aaaaaatcca gtagatcttt tcataataaa acgcattgta
    21661 tcaagtgtta ggagctgata tcatgcgttt ttctgctttt aagatttttt ccaactctgt
    21721 ttgtaagcgc atcataacaa agggtctagg attcagggct ctcctcctat atactattag
    21781 taaagtaaaa ctaagagagg atattttagt gtcgcagtct attgttcctg tagagattcc
    21841 acaatattgt cgttttgatt ctaaaaagag aaatggaatt ctgtttaacg ttcgtattgc
    21901 caatcttaaa tttacctttt ttagattaga cttcctgcga aataaaatat ggtatagtag
    21961 ttctatgaat gatgaagcaa gtaaacaact aactgatgca cgatttaagc gtcttgttgg
    22021 tgttcagcgc acgacttttg aagagatgtt agctgtatta aaaacagctt atcaacttaa
    22081 acacgcaaaa ggtggacgaa aacctaaatt aagcctagaa gaccttctta tggccactct
    22141 tcaatatgtg cgagaatatc gaacttatga agaaattgtg gctgtttttg gtatccacga
    22201 aagcaactta atccgtcgga gctaatgggt tgaagtaact cttgttcaaa gtggtgttac
    22261 gatttcaaga actcctctca gctctgaggc cacggtaatg attgatgcga cggaagtaaa
    22321 aatcaatcgc cctaaaaaaa caattagcga attattcttg taaaaaaatg ccacgctatg
    22381 aaggctcaag cgattgtcac aagtcaaggg agaattgttt ctttggatat cactgtgaac
    22441 tattgtcatg atatgaagtt gttcaaaatg agttgcagaa atatcggaca agctggtaaa
    22501 atcttggctg acagtggtta tcaagggctc atgaagatat atcctcaagc acaaactcca
    22561 cgtaaatcca gcaaactcaa gccgctaaca gttgaagata aagcctgtaa ccatgcgcta
    22621 tccaaggaga gaagcaaggt tgagaacatc tttgccaaag taaaaacgtt taaaataatt
    22681 tcaacaacct atcgaaatca tcgtaaacgc ttcggattac gaatgaattt gagtgctggt
    22741 attatcaatc atgaactagg attctagttt tgcaggaagt ctattgaggt attgagctag
    22801 tttatgaaaa aattgggtga aaagtcgagt gttttagaaa cccacagtgt agtattctag
    22861 tttcaatcca ctatattttg ctactccccg taaagtttct attttccctg atttctgata
    22921 taatagaaat attgacttca agagtaagga agagaagatg aacgcattat taaatggaat
    22981 gaatgaccgt caggctgagg cggtgcaaac gacagaaggt cccttgctaa tcatggcagg
    23041 ggctggttct ggaaagactc gtgttttaac ccaccgtatc gcttatttga ttgatgaaaa
    23101 gctggtcaat ccttggaata tcttggccat tacctttacc aacaaggctg cgcgtgagat
    23161 gaaagagcgt gcttatagcc tcaatccagc tactcaggac tgtctgattg cgaccttcca
    23221 ctccatgtgt gtgcgtattt tgcgtcgcga tgcggaccat attggctaca atcgtaattt
    23281 tacaattgtg gatcctggtg aacagcgaac gctcatgaaa cgtattctca aacagttgaa
    23341 cttggatcct aaaaaatgga atgaacgaac tattttgggg accatttcca atgctaagaa
    23401 taatttgatt gatgatgttg cttatgctgc ccaagctggc gatatgtata cgcaaattgt
    23461 ggcccagtgt tatacagcct atcaaaaaga acttcgtcag tctgaatccg ttgactttga
    23521 tgatttgatt atgctgacct tgcgtctctt tgatcaaaat cctgatgttt tgacctacta
    23581 ccagcaaaaa ttccaataca tccacgttga tgagtaccaa gataccaacc acgctcagta
    23641 ccaattggtc aaactcttgg cttcccgttt taaaaatatc tgtgtggttg gggatgcgga
    23701 ccagtctatc tacggttggc gtggtgctga tatgcagaat atcttggact ttgaaaagga
    23761 ttaccccaaa gccaaggttg tcttgctgga ggaaaattac cgctcaacca aaaccattct
    23821 ccaagcggcc aacgaggtta ttaaaaataa taaaaatcgc cgtcctaaaa atctctggac
    23881 tcaaaacgct gatggggagc aaatcgttta ctatcgtgcc gatgatgagc tggatgaggc
    23941 tgtatttgta gccagaacca tcgatgaact tagtcgcagt caaaacttcc ttcataagga
    24001 ttttgcagtt ctctatcgga ctaatgccca gtcccgtaca attgaggaag ccctgctcaa
    24061 gtctaacatt ccttatacca tggttggcgg aaccaaattc tacagccgta aggaaattcg
    24121 cgatattatt gcttatctca accttattgc taatttgagt gacaatatta gttttgagcg
    24181 tattatcaac gagcctaaac gtggaattgg tctaggtaca gttgagaaaa tccgtgattt
    24241 tgcaaatttg caaaatatgt ctatgctgga tgcttctgct aatattatgt tgtctggtat
    24301 caagggtaag gcagcccaat ctatctggga ttttgccaat atgatgcttg atttgcggga
    24361 gcagctagac cacttaagca ttacagagtt ggttgagtcc gtcctagaaa aaacaggtta
    24421 tgtcgatatt cttaacgccc aagcgactct agaaagcaag gcacgggttg aaaatatcga
    24481 agagtttctt tctgttacga agaactttga tgacaccacg gatgtgacag aagaggaaac
    24541 tggtctggac aaactgagtc gtttcttaaa tgacttggct ttgattgccg acacagattc
    24601 aggtagtcag gagacatcag aagtgacctt gatgaccctg catgctgcca aaggtctcga
    24661 atttccagtt gtctttttga ttgggatgga agaaaatgtc tttccactta gtcgtgcgac
    24721 tgaagatcca gatgaattag aagaagagcg ccgtctagcc tatgtaggta tcacgcgtgc
    24781 agagaaaatt ctctatctga ccaatgccaa ctcacgcttg ctttttggtc gtaccaatta
    24841 taaccgtccg actcgtttta ttaacgaaat cagttcagac ttgcttgagt atcaaggtct
    24901 ggctcgtcct gcaaatacaa gctttaaggc atcatatagc agtggtagta tttcctttgg
    24961 tcaaggtatg agtttggctc aggctcttca agaccgtaaa cgcggtgctg ccccaaaatc
    25021 aatccagtca agcggtcttc catttggtca atttacagct ggcgcaaaac cagcatctag
    25081 cgaggcaaat tggtccattg gtgatattgc tctccacaag aaatggggag agggaaccgt
    25141 tctggaagtt tcaggtagcg gtgctaggca ggaattgaaa atcaatttcc cagaagtagg
    25201 tttgaaaaaa cttttagcca gtgtggctcc aattgagaaa aaaatctaat tttccatcct
    25261 tctcacgaat aataaagtga ggaggatttt tatgtacagt atttcattcc aagaagattc
    25321 actattacca agagaaaggc tggccaagga aggagttgaa gcgcttagta accaagagtt
    25381 gctagctatt ttactcagga caggaacacg tcaagttagc gtttttgaaa ttgcccaaaa
    25441 agtcttgaac aatctttcaa gcctaacgga tttgaaaaaa atgaccctgc aggaattgca
    25501 gagtttgtct ggtattgggc gtgttaaggc catagaatta caagctatga ttgaactggg
    25561 gcatcgtatt cacaaacacg agactcttga aatggaaagt attctcagca gtcaaaagtt
    25621 ggccaagaag atgcagcagg aattagggga taaaaaacaa gagcacctgg tggcactcta
    25681 tctcaatact caaaatcaaa tcatccatca gcagaccatt tttatcgggt ctgtaactcg
    25741 tagtatcgct gaaccgcgag agattcttca ctatgcaatc aagcatatgg cgacttctct
    25801 tatcttggtc cacaatcatc cttcaggagc ggtagcgcct agccaaaatg atgatcatgt
    25861 cactaaactt gttaaagaag cctgcgaatt gatggggatt gttctcttgg accatttgat
    25921 tgtctctcat tctaattact ttagttatcg tgaaaagaca gatttaatct aaagttcatt
    25981 aacgacatag tcaaagagtt ttttatcttt gggacgattt tcaaaaagaa gttctggatg
    26041 ccattggaca ccgagaaagg cgacatcatc cgtactcatg acagcctcaa tgataccatc
    26101 tttaggatca tgagccacaa cttttaaatt tggtgctaag tccttgatgc tctggtggtg
    26161 gaaggagttg atatgagaga tttctccata gatttcttgg agaacggtat ctggttctgt
    26221 taccaagcgt tgagttgtgt actcaacaga agaatcctgc caatggtctt cgatatcttg
    26281 gtacaaagtt ccacccatgg caacgttaaa gagttgggta ccacggcaga cagagaaaat
    26341 gggctttttc tgtttaatag cttccttgat gagggtcagt tcgaagatat ctctttgaag
    26401 gtgatagtca tcgctatcaa tggttttggg ttcgccataa aattttggat cgacattttg
    26461 cccacctgtc aagatgagct tgtcaatcaa actgatatag tggcaggcca tttcttgatc
    26521 accaatcggt aggatgatgg gaatccctcc agcatcttta acgccttcaa caaagccttt
    26581 tgctgcgtag ctcatcatga tgtcatcatc tggatgagct ttttcgtttc ctgtaatccc
    26641 aataactggt tttttcataa aatgattttc gctttctaat cctcttttcg catgaagtag
    26701 aggagggttt ggagttcact tgtcaaatcg acatactgaa cgaccacgtc ttttggtaaa
    26761 tgcagatgga ctggtgaaaa actgagaatt cctttcacac cagcatcaac caagagatta
    26821 gcaacctctt gtgacttgac gctgggaaca gttaggatag cagtcttcac atcagcatcc
    26881 ttgattttat ccttgatctg agaaatcccg taaatgggaa tcccgtcagg agtttgggta
    26941 ccgacttcag gatggtcgtc taggtcaaag gccatgataa tcttcatctt gttacgttcg
    27001 tggaagcggt agtggagaag ggcatggccc atatttccaa taccaaccag catgacattg
    27061 gtaatagagt tgtcattgag caaatcggca aaaaatgtca ttagtttttt gacatcatag
    27121 ccaaaaccac gacgaccaag ttcaccaaaa taggaaaaat cacgacgtac ggtcgctgaa
    27181 tcaataccga tagcctctgc aatttgctta gagttggcac gttcaatctt ttctgcatga
    27241 aatctcttaa aaattcgata gtagagagag agtctttttg ctgtagcttt tggaatagca
    27301 aactgtttat ctttcacaaa atcacaacct ttctattctt ctattttata gaaacattgt
    27361 gaaaaaatca acaaaaataa gaaaaaacta agaaaaatct tagttttgat gtaaaaaatc
    27421 tgcatgagat agaaaacggt agaggtctcc gaccagaccc tgataaactt tttggcccct
    27481 aaaagtcaga gaagtcacat aaagtgtatc tggtaaggtt acacatcctg acaaagtcaa
    27541 catgagagcc tcatgatcct catacttgag agtacgctct acatgatagc agtccttata
    27601 ggtcagttca aacattttgg ctctatcttt ccgattttgt aaagacacca cgttctacca
    27661 agctatccat gaggaagtag aatttttcct gatgaatatg gtggtcttct gatttgaaaa
    27721 tatcaactag acgaaggcca aacttgtcag tgatattgat tttagcccct gtaagttcct
    27781 tgttaatgat gattttgagt tggaagcctt caccgctgtt tggcactttt tccaaaaggc
    27841 gagtcagttc atagttacca accttagttt caaaaaaggt gttatctttg agggtgaatt
    27901 ttttaacaga agggctaaga gtgtaatcgt aacgacaatt ttttaactga atgatttttt
    27961 caaatgccat atggctaacc tccgataatt tcttttaagg tttttgcgag ggtttgtagg
    28021 tcttcaacgg tattttgtgg cgacaaactg atgcgaaggg attccttcaa gcgttctgaa
    28081 tttgcgccat acatggcttc aagaacatgg ctggattgga caacgcctgc agtacaggct
    28141 gagccagtag agattgaaat tccagctaaa tctagccgaa ggagtaagag gtcatttttc
    28201 tgaccaggaa atccaatatt gagaacataa gggagatgat gttttcctct attcaagtaa
    28261 tactgaatgc cctccagctc tgccagaaag gcagtttcta gattttgtac atgttgaaaa
    28321 tgttcttctt gtttttctag gtcttctttt agggctgcaa ccatgcctac gatagcaggc
    28381 agattttcag ttcctgcacg ttttttctgt tcctggtctc cgccatgtag ataggaatca
    28441 aagtccatgc tagatgcgta gagaaaaccg attcccttag gaccatggaa tttgtgggca
    28501 gaagcagtga gaaaatcaat gcccaattct tctgaatgaa ttgggatttt accaatagcc
    28561 tgaactgcat caacatgata ggcagcaggg tgttgcttga gtatttggcc aatttcagcg
    28621 atgggcagta ggtttcctgt ctcattattg gcaaacatgg tagaaaccaa aatcgtatcg
    28681 tcacgtaaag ccttttgaat ttgctgggct gtgatttctt gattttctgg ctggataatg
    28741 gttgcttcaa acccaaagtg ttgaaccaag taatcaattg tttcaaggac agcatggtgc
    28801 tcgatggcag ttgtgatgat atgttttcct tgttcttggt gacgaagaca gtagccaatg
    28861 atggtagtat tattgccttc agtcccacca gaagtgaaaa agatatgttg aggttttgtc
    28921 cttagtaact gggctagttc ctgacgggct tctcgcaaga gtttgccagc ttgacgacca
    28981 tgaccatgaa tactagaagg atttccgtgg gtttcttgca taaccttggt catagctgaa
    29041 atagcaactg ctgacatagg agtcgttgca gcattgtcca aataaatcaa agaatcacct
    29101 tatttctttt tattgtaggc aaagagtggg ctgactggtt ttctttcgtg aatacggacg
    29161 atagcatcac caattaactc actagcagtg atgtagcata catttttagg agttttttct
    29221 tttgttgcta ctgaatcagt cacaagaatt tctttaatat tagtattgtc aagaagctca
    29281 gcagctccct cgacgaagag accgtggcta gaaacagcat aaatttctgt agctccttca
    29341 cgttcaacga ttttagaagc ttcagagaag gtacgtcctg tatttaaaat atcatcaatc
    29401 aagatagctt tcttaccttc aacatcacca ataatataac cttcgttacg agttgcatcg
    29461 tcttgagggt agtcgataat ggcgatagga gcatcaagat attcagccag gctacgcgca
    29521 cgtttgacac ctgaattttt agggctaacg acaacaacat ctgaaccaag caatccttta
    29581 tcgcagtaat gttttgcgaa taggggaaca gtgaaaagat tatccactgg aatatcaaag
    29641 aaaccttgaa cctgaacggc atgcaaatca agagtcagga tacgatcaac tccagcctta
    29701 accagcatat tggcaactag ttttgctgta agtggctcac gaggacaagc aatgcggtct
    29761 tgacgtgcat agccaaaata tggaaggaca acgttgatac tgtgggcact tgcacgcaca
    29821 caagcatcga ccatgattaa caattccatt aggtggttgt tgacagggaa acttgttgat
    29881 tggatgatgt aaacatcata accacggaca ctttcttcga tatttacttg gatttctccg
    29941 tctgaaaatt gacgtgatga tagttttcca agtgggacac caacagcttg ggcaattttt
    30001 tgtgcaatct cttggttaga gttgagtgcg aaaagtttca tgttttttct atctgacatt
    30061 atagaccgtc ctctgtaaac tttataaatc ctagttatat ttaccttaca tatatgaact
    30121 gggatttgtg tatttttatc ttttctattt taccaaaaaa tggagattat ttcagctatt
    30181 tttcatactt ttgacaaatc gaaccaattt tgaaggagct ttttggtagg aaatctgatt
    30241 tttctctaaa aattgtcgga aatcctgttt gccttgctca tgattttcca cttcaagctc
    30301 caattcgtaa tctgttatat caaagtatcg gctctgatcc agtgccatga gaccaatagc
    30361 tgttttcatt tcatagcgaa gcgttgttag acaaccaaga acctgccagt tcttactttg
    30421 gataccatgt ttcgccaatt catccagtac tagcccttga ggaagttctt ccttactcag
    30481 atagttctca gcatctttta gttgcaattt ttggttgtat tccatgtttc caacactctg
    30541 cgggactttg agtgtcaact cagcccagtc ttcaaaggtt cgaatgcgca tagcgacttt
    30601 cttttctcgc agttcaaaat caggcgtgtc gatgtagtaa tttgtttgaa gaacaggagt
    30661 gacacctgtg aactggtctt ttagacgatt gtattcatct tttttcaata gtgttttcaa
    30721 ttcaatttct aaatgtttca tttttcttac ctttttttat cgttgaaagc ggatttatgg
    30781 tataataagc attgtattta ttgtatatga atctggagaa aaaatcaaag atatttttga
    30841 cggataatat gagaacaagg gagaatatat gaccttagaa tgggaagaat ttctagatcc
    30901 ttacattcaa gctgttggtg agttaaagat taaacttcgt ggtattcgta agcaatatcg
    30961 taagcaaaat aagcattctc caattgagtt tgtgaccggt cgagttaagc caattgagag
    31021 catcaaagaa aaaatggctc gtcgtggcat tacttatgcg accttggaac acgatttgca
    31081 ggatattgct ggcttacgtg tgatggttca gtttgtagat gacgtcaagg aagtagtgga
    31141 tattttgcac aagcgtcagg atatgcgaat catacaggag cgagattaca ttactcatag
    31201 aaaagcatca ggctatcgtt cctatcatgt ggtagtagaa tatacggttg ataccatcaa
    31261 tggagttaag actattttgg cagaaattca aattcgtact ttggccatga atttctgggc
    31321 aacgatagaa cattctctca actacaagta ccaaggggat ttcccagatg agattaagaa
    31381 gcgactggaa attacagcta gaatcgccca tcagttggat gaagaaatgg gtgaaattcg
    31441 tgatgatatc caagaagctc aggcactttt tgatcctttg agtagaaaat taaatgacgg
    31501 tgtaggaaac agtgacgata cagatgaaga atacaggtaa acgaattgat ctgatagcca
    31561 atagaaaacc gcagagtcaa agggttttgt atgaattgcg agatcgtttg aagagaaatc
    31621 agtttatact caatgatacc aatccggata ttgtcatttc cattggcggg gatggtatgc
    31681 tcttgtcggc ctttcataag tacgaaaatc agcttgagaa ggtccgcttt atcggtcttc
    31741 acactggaca tttgggcttc tatacagatt atcgtgattt tgagttggac aagctagtga
    31801 ctaatttgca gctagatact ggggcaaggg tttcttaccc tgttctgaat gtgaaggtct
    31861 ttcttgaaaa tggtgaagtt aagattttca gagcactcaa cgaagccagc atccgcaggt
    31921 ctgatcgaac catggtggca gatattgtaa taaatggtgt tccctttgaa cgttttcgtg
    31981 gagacgggct aacagtttcg acaccgactg gtagtactgc ctataacaag tctcttggcg
    32041 gtgctgtttt acaccctacc attgaagctt tgcaattaac ggaaattgcc agccttaata
    32101 atcgtgtcta tcgaacactg ggctcttcca ttattgtgcc taagaaggat aagattgaac
    32161 ttattccaac aagaaacgat tatcatacta tttcggttga caatagcgtt tattctttcc
    32221 gtaatattga gcgtattgag tatcaaatcg cccatcataa gattcacttt gtcgcgactc
    32281 ctagccatac cagtttctgg aaccgtgtta aggatgcctt tatcggtgag gtggatgaat
    32341 gaggtttgaa tttatcgcag atgaacatgt caaggttaag accttcttaa aaaagcacga
    32401 ggtttctaag ggattgctgg ccaagattaa gtttcgaggt ggagctattc tggtcaataa
    32461 tcaaccgcaa aatgcaacgt atctattgga cgttggagac tacgttacca ttgacattcc
    32521 cgctgagaaa ggctttgaaa ccttggaggc tattgagctt ccattagata ttctctatga
    32581 ggatgaccac tttctagtct tgaataaacc ctatggagtg gcttctattc ctagtgttaa
    32641 tcactctaat accattgcca attttatcaa gggttactat gtcaagcaaa attatgaaaa
    32701 tcagcaggtt cacattgtta ccagactaga tagggacact tctggcttga tgctctttgc
    32761 caagcacggt tatgcccatg cacgattaga caagcagttg cagaagaaat ctatcgagaa
    32821 acgctacttt gctttggtta agggagatgg acatttggaa ccagaagggg aaattattgc
    32881 tccgattgcg cgtgatgaag attccattat taccagacga gtggctaaag gcggaaagta
    32941 tgcccatact tcatacaaga ttgtagcttc ttatggaaat attcacttgg tctatattca
    33001 cctgcacact ggtcgaaccc atcaaatccg agtccatttt tctcatatcg gttttccttt
    33061 gctgggagat gatttgtatg gtggtagtct ggaagatggt attcaacgtc aggctctgca
    33121 ttgccattac ctatcctttt atcatccatt tttagagcaa gacttgcagt tagaaagtcc
    33181 cttgccggat gatttcagta accttattac ccagttatca actaatactc tataaaaact
    33241 gtctcagagt ataattatta tcttaaagga gaaaactcat ggaagttttt gaaagtctca
    33301 aagccaacct tgttggtaaa aatgctcgta tcgttctccc tgaaggggaa gagcctcgta
    33361 ttcttcaagc aacaaaacgc ttagtaaaag aaacagaagt gattcctgtt ttgcttggaa
    33421 atcctgaaaa aattaaaatt tatcttgaaa ttgaaggaat catggatggt tatgaggtca
    33481 tcgaccctca acattatcct caatttgaag aaatggtttc tgccttggtg gagcgtcgca
    33541 agggcaaaat gactgaagaa gatgtacgca aggttttggt tgaagatgtc aactactttg
    33601 gtgtgatgtt ggtttacttg ggcttggttg atggaatggt gtcaggagcg attcactcaa
    33661 cagcttcaac agttcgccca gctctacaaa tcatcaaaac tcgtccaaat gtaactcgta
    33721 cttcaggagc cttcctcatg gttcgtggta cggaacgtta cctatttgga gactgtgcca
    33781 ttaatatcaa tccagatgca gaagccttgg ctgaaattgc catcaactca gcaatcacag
    33841 ctaagatgtt tggcatcgaa cctaaaattg ccatgttgag ctattctact aaaggttcag
    33901 ggtttggtga aagcgttgat aaggtcgttg aagcaactaa aattgctcac gacttgcgtc
    33961 ctgaccttga aatcgatggt gagttgcaat ttgatgcggc ctttgttccc gaaactgcag
    34021 ctctgaaagc tccgggaagt acagtagctg gtcaagcaaa tgtcttcatc ttcccaggta
    34081 tcgaggcagg aaatatcggt tacaagatgg ctgaacgcct gggtggcttt gcggctgtag
    34141 gacctgtttt gcaaggttta aacaagccag ttaatgatct ttctcgtgga tgtaatgcag
    34201 atgatgttta caagttgacc ctcatcacag cagctcaagc agttcatcaa tagtgaaaac
    34261 tataaagtga tatactatgc tatactgtag ttatgaaact atgtacgaaa agcactgcca
    34321 ttaattcctg agaactaaat tactgattgg tgtcaaaaag gaaaacttcc aagcgatgat
    34381 atcctgtcta tacacgacct atagaaatct gtaatataca tatccgtaaa acgataaatt
    34441 ccctttttga ttttaaatga gtatgaaaag agaatttttt ggctctttgt caactgtagt
    34501 gggttgaagt
//
LOCUS       DAVLBE010000018        34373 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.018, whole genome shotgun sequence.
ACCESSION   DAVLBE010000018 DAVLBE010000000
VERSION     DAVLBE010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34373)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34373)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34373
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.018"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            538..990
                     /locus_tag="VXB91_000920"
     CDS             538..990
                     /locus_tag="VXB91_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEV0470396.1"
                     /translation="MIITKISRLGTYVGVNPHFATLIDFLEKTGLENLTEGSIAIDGN
                     RLFGNCFTYLADGQAGAFFETHQKYLDIHLVLENEEAMAVTSPENVSVTQEYDEEKDI
                     ELYTGKVEQLVQLRAGECLITFPEDLHQPKVRINDEPVKKVVFKVAIS"
     gene            1009..2346
                     /locus_tag="VXB91_000921"
     CDS             1009..2346
                     /locus_tag="VXB91_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HEV0470397.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            2425..3309
                     /locus_tag="VXB91_000922"
     CDS             2425..3309
                     /locus_tag="VXB91_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0470398.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTVFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            3309..4142
                     /locus_tag="VXB91_000923"
     CDS             3309..4142
                     /locus_tag="VXB91_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV0470399.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAIFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLIAIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            4160..6253
                     /gene="nanB"
                     /locus_tag="VXB91_000924"
     CDS             4160..6253
                     /gene="nanB"
                     /locus_tag="VXB91_000924"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HEV0470400.1"
                     /translation="MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQ
                     GGSYQLNNKSIDISPLLLDKLSGESQTVVMKFKADEPNSLQALFGLSNSKAGFKNNYF
                     SIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
                     VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKGSIGEISLFNKAISDQ
                     EVSTIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKIN
                     IATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDK
                     KSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVY
                     DETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSGSLREKHNGKQVPMNVFYKDSL
                     FKVTPTNYIAMTTSQNRGESWEQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFAT
                     YTSGELTYLISDDSGQTWKKSSASIPFKNATAEAQMVELRDGVIRTFFRTTTGKIAYM
                     TSRDSGETWSEVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQL
                     VVGLVNKEDDSIDWKYHYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLS
                     NVVQYIDLEINDLTK"
     gene            6265..7368
                     /locus_tag="VXB91_000925"
     CDS             6265..7368
                     /locus_tag="VXB91_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEV0470401.1"
                     /translation="MVKYGVVGAGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDACKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQPSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVKLSEIVK"
     gene            7542..8240
                     /locus_tag="VXB91_000926"
     CDS             7542..8240
                     /locus_tag="VXB91_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEV0470402.1"
                     /translation="MPQISKEALIEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAA
                     EQGGAVGIRANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIE
                     VIALDCTKRERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTL
                     SGYTSYSPKVDGPDFELIKKLCDAGVDVIAEGKIHTPEQAKQILEYGVRGIVVGGAIT
                     RPKEITERFVASLK"
     gene            8259..9776
                     /locus_tag="VXB91_000927"
     CDS             8259..9776
                     /locus_tag="VXB91_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEV0470403.1"
                     /translation="MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPIL
                     DNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATI
                     KALVKLFMAEGSAIDTGVIGALAVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTS
                     FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPM
                     FWYTELGGVETIAGQTVVGAQKIFFAQLADPAHSGLFTEGTRFFAGRFSTMMFGLPAA
                     CLAMYHSVPKNRRKKYAGLFFGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVS
                     FFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPIGLIWSVLYYIIFRWFI
                     TQFNVLTPGRGEEVDSKEISESADSTSNTADYLKQDSLQIIRALGGSNNIEDVDACVT
                     RLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD"
     gene            9901..11229
                     /locus_tag="VXB91_000928"
     CDS             9901..11229
                     /locus_tag="VXB91_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0470404.1"
                     /translation="MKFRKLACTVLAGAAVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            11481..12347
                     /locus_tag="VXB91_000929"
     CDS             11481..12347
                     /locus_tag="VXB91_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0470405.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAIMIAIVSF
                     VQFKVLGNDVEY"
     gene            12363..13202
                     /locus_tag="VXB91_000930"
     CDS             12363..13202
                     /locus_tag="VXB91_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV0470406.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            13474..13926
                     /locus_tag="VXB91_000931"
     CDS             13474..13926
                     /locus_tag="VXB91_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEV0470407.1"
                     /translation="MIFDDLKNITFYKGIHPNLDKAIDYLYQHRKDSFELGKYEIDGD
                     KVFLVVQENVLNQVENNRFEHHKNYADLHLLIEGHEYSSYGSRIKDEAVAFDEASDIG
                     FVHCHEHYPLLLGYHNFAIFFPGEPHQPNGYAGMEEKVRKYLFKILID"
     gene            14023..14367
                     /locus_tag="VXB91_000932"
     CDS             14023..14367
                     /locus_tag="VXB91_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0470408.1"
                     /translation="MVSSKYAARASFLDGQGITVDEMAWIIRGIVTALIGRYIKLGTY
                     AVKYGISMARSILSRAAATAAARVGLLTKIFGWILRIAVLAADVYGNFANNIAVAWDA
                     HDKIPNNGRINF"
     gene            14654..15298
                     /locus_tag="VXB91_000933"
     CDS             14654..15298
                     /locus_tag="VXB91_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEV0470409.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEVKKSRRVPVFKIYLRSFKQNLKLGLQLGLMELGIVFLTLSDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLTWKEVLQKGLILASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSVFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            15467..16384
                     /locus_tag="VXB91_000934"
     CDS             15467..16384
                     /locus_tag="VXB91_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HEV0470410.1"
                     /translation="MSDLKKYEGVIPAFYACYDEQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTSSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGAKAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTAAHGNMYGVIKEVLKINEGLNIGSVR
                     SPLTPVTEDDRPVVEAAAALIRETKERFL"
     gene            16402..17286
                     /locus_tag="VXB91_000935"
     CDS             16402..17286
                     /locus_tag="VXB91_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV0470411.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGPVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASVTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFKEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(17302..18153)
                     /locus_tag="VXB91_000936"
     CDS             complement(17302..18153)
                     /locus_tag="VXB91_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEV0470412.1"
                     /translation="MDKPDIATIIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANQVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLLDAKEMGAKTVLFTSVPNKNSQTYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            18353..20410
                     /gene="pbp2b"
                     /locus_tag="VXB91_000937"
     CDS             18353..20410
                     /gene="pbp2b"
                     /locus_tag="VXB91_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HEV0470413.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNK
                     DFYEKKLASASQTKITSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETA
                     KKLLTYVSISSPNLTERQLADYYLADPEIYKKIVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQSIVFQGSAPINSWYTQAYGSFPITAVQALEYSSN
                     TYMVQTALGLMGQTYQPNMFVGTSNLESAMEKLRSTFGEYGLGTATGIDLPDESTGFV
                     PKEYSFANYITNAFGQFDNYTPMQLAQYVATIANNGVRVAPRIVEGIYGNNDKGGLGD
                     LIQQLQPTEMNKVNISDSDMSILHQGFYQVAHGTSGLTTGRAFSNGALVSISGKTGTA
                     ESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYH
                     PMN"
     gene            20421..21017
                     /gene="recR"
                     /locus_tag="VXB91_000938"
     CDS             20421..21017
                     /gene="recR"
                     /locus_tag="VXB91_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HEV0470414.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSADDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDSTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            21193..22236
                     /locus_tag="VXB91_000939"
     CDS             21193..22236
                     /locus_tag="VXB91_000939"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HEV0470415.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVNYDRFTVKTFFISQ
                     SGDSIKTQEFSHAPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFTKPSNMGSSVGISKSENQEELRQALKLAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKVTMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWENMGISYPELIERLVDL
                     AKESFDKREAHLI"
     gene            22320..23693
                     /locus_tag="VXB91_000940"
     CDS             22320..23693
                     /locus_tag="VXB91_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HEV0470416.1"
                     /translation="MKLTIHEIAQVVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVP
                     LKGARDGHDFIETAFENGAAVTLSEKEVSNHPYILVDDVLTAFQSLASYYLEKTTVDV
                     FAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLAP
                     ADPIVEDYLPIDKKVVRFGQGAELEITDLVERKDSLTFKANFLEQALDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIRLAFQHLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGDQSVQLHNQMILSLSPDVLDIVIFYGEDIAQ
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLGAYDQILLKGSNSMNLAKLVE
                     SLENECK"
     gene            23680..24291
                     /locus_tag="VXB91_000941"
     CDS             23680..24291
                     /locus_tag="VXB91_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV0470417.1"
                     /translation="MNASDFAKYLQRMIALTDTGLTFTKDPFDRERYEDLRSLLSEML
                     NQVSDLDADEVAELLKPTSAYATPLMDVRAWIVEDEKICLVRGQGENDWALPGGFGEV
                     GYSPTENILKEIEEETGFKAKVERLLAVFDTNRFQLQSKQYAKFVFECKLLDGQFQEN
                     QEIADLQFFAIDQLPNLSEKRITKEQIELLWQVYQGHRGQYLD"
     gene            24382..25086
                     /locus_tag="VXB91_000942"
     CDS             24382..25086
                     /locus_tag="VXB91_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HEV0470418.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTFYTAHRYRENK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            25305..26678
                     /gene="ftsA"
                     /locus_tag="VXB91_000943"
     CDS             25305..26678
                     /gene="ftsA"
                     /locus_tag="VXB91_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HEV0470419.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVEPVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            26695..27954
                     /gene="ftsZ"
                     /locus_tag="VXB91_000944"
     CDS             26695..27954
                     /gene="ftsZ"
                     /locus_tag="VXB91_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HEV0470420.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARSATN
                     YRETVKPAHSHGFDRHFDMAETVELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            27959..28630
                     /locus_tag="VXB91_000945"
     CDS             27959..28630
                     /locus_tag="VXB91_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HEV0470421.1"
                     /translation="MNVKENTELVFREVAEASLSAHRESGSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDVIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELAGLDKIEYVGLMTMA
                     PFEASSEQLKEIFKAAQDLQREIQEKQIPNIPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            28640..29179
                     /locus_tag="VXB91_000946"
     CDS             28640..29179
                     /locus_tag="VXB91_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HEV0470422.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTSVNSSQEPALP
                     MNQPSQSAGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            29179..29442
                     /locus_tag="VXB91_000947"
     CDS             29179..29442
                     /locus_tag="VXB91_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HEV0470423.1"
                     /translation="MIFLIRMIYNAVDIYSLILIAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            29439..30224
                     /locus_tag="VXB91_000948"
     CDS             29439..30224
                     /locus_tag="VXB91_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HEV0470424.1"
                     /translation="MNKGIYQHFSIEDRPFLDKGMEWIKKVEDSYAPFLTPFINPHQE
                     KLLKILAKTYGLACSSSGEFVSSEYVRVLLYPDYFQPEFSDFEISLQEIVYSNKFEHL
                     THAKILGTVINQLGIERKLFGDILVDEERAQIMINQQFLLLFQDGLKKIGRIPVSLEE
                     RPFTEKIDKLEQYRELDLSVSSFRLDVLLSNVLKLSRNQANQLIEKKLVQVNYHVVDK
                     SDYTVQVGDLISVRKFGRLRLLQDKGQTKKEKKKITVQLLLSK"
     gene            30233..31021
                     /gene="divIVA"
                     /locus_tag="VXB91_000949"
     CDS             30233..31021
                     /gene="divIVA"
                     /locus_tag="VXB91_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HEV0470425.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DILRPTATYLQTSDEAFKEVVSEVLGEPIPAPIEEEPIDMTRQFSQAEMEELQARIEV
                     ADKELSEFEAQIKQEVETPTPVVSPQVEEEPLLIQLAQCMKNQK"
     gene            31369..34161
                     /locus_tag="VXB91_000950"
     CDS             31369..34161
                     /locus_tag="VXB91_000950"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HEV0470426.1"
                     /translation="MKLKDTLNLGKTAFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     EGKPHFVLHDGPPYANGNIHVGHAMNHISKDIIIRSKSMSGFNAPYIPGWDTHGLPIE
                     QVLAKQGVKRKEMDLVEYLKLCREYALSQVYKQRDDFKRLGMSGDWENLYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GILDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPASETRKFVVAAELLTSLSEK
                     FGWADVQVLATYRGQELNHIVTEHPWDTAVDELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANGLEVAVTVDERGIMMANAGPEFEGQFYDKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDAIDKVKFHTEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMTAETIEHVAQLFEVHGSSIWWERDAKDLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVLVNRPNLTYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFTLDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDVVAYDELRSVDKYMT
                     IRFNQLVKTIRDAYADFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFEAEDFVQLSELPEAQTFANQEEVLD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SDLTIAEGPAPEAALSFEDVAFTVERAAGQVCDRCRRIDPTTAERSYQAVICDHCASI
                     VEENFAEAVAEGFEEK"
BASE COUNT        10571 a         6069 c         7477 g        10256 t
ORIGIN      
        1 aaatatagag tatttctctc ttaaaagttt ttggtgaaac gagatgtaga aaggagattt
       61 agccaaagag tctattagtg ctagaataat agattagaat tattttagaa aaacgaagtg
      121 agcagcttat aaattcaagt ccccaaatag attcatacta gtatcttttg caaaaaataa
      181 agggcgactt ccttcatgaa tatcaatttc atctataagg aaggtagcta attgaactaa
      241 cttatttatt ctgtttgtcg ctagaaaaat cagacctcct tgtgaagatt gaggagatac
      301 ttaatgaaaa tcaaagaaga aactagcaag ctagtagcag attgcccaaa acaccgcttt
      361 gaggttgtag ataagactga cctatataat ccaaggtgaa gcgactgtgg tttgaagaga
      421 ttttcaaaga gtataggcta gagagtagtg tttttatgtc cttctagtag aaaatgctag
      481 acagaagaat ggggaacttg gataggaaaa atagattgag aaaggaggtt agaagagatg
      541 attattacaa aaattagccg tttaggaact tatgtgggag tcaatccaca ttttgcaaca
      601 ttaatagatt ttctagaaaa aacaggacta gaaaatttaa cagaaggttc gattgctatc
      661 gatggtaatc gattgtttgg gaattgcttt acttatctag cagatggtca agcaggggct
      721 ttctttgaaa cacaccaaaa atatttggat attcatttag ttttggaaaa cgaagaagcc
      781 atggctgtta catcgccgga aaatgtaagc gttacccaag aatatgatga agagaaagat
      841 attgaattat acacagggaa agtggaacag ttggttcagt tgagagctgg cgaatgcctc
      901 atcacttttc cagaagattt acatcaaccc aaggttcgta taaatgatga acctgtgaaa
      961 aaagttgtct ttaaagttgc gatttcttaa tgtagaaaga gaagaacgat gaaaaaaatg
     1021 agaaagtttt tatgtctagc tggaattgcg ctagcggctg ttgccttggt agcttgttca
     1081 ggaaaaaaag aagctacaac tagtactgaa ccaccaacag aattatctgg tgagattaca
     1141 atgtggcact cctttactca aggaccccgt ttagaaagta ttcaaaaatc agcagatgct
     1201 ttcatgcaaa agcatccaaa aacgaaaatc aagattgaaa cattttcttg gaatgacttc
     1261 tatactaaat ggactacagg tttagcaaat ggaaatgtgc cagatatcag tacagctctt
     1321 cctaaccaag taatggaaat ggtcaactca gatgctttgg ttccgctaaa tgattctatc
     1381 aagcgtattg gacaagataa atttaacgaa actgccttaa atgaagcaaa aatcggagat
     1441 gattactact ctgttcctct ttattcacat gcacaagtca tgtgggttag aacagatttg
     1501 ttaaaagaac ataatattga ggttcctaaa acttgggatc aactctatga agcttctaaa
     1561 aaattgaaag aagctggagt ttatggcttg tctgttccgt ttggaacaaa tgacttaatg
     1621 gcaacacgtt tcttgaactt ctacgtacgt agtggtggag gaagcctctt aacaaaagat
     1681 cttaaagcag acttgacaag ccaacttgct caagatggta ttaaatactg ggttaaattg
     1741 tataaagaaa tctcacctca agattctttg aactttaatg tccttcaaca agctaccttg
     1801 ttctatcaag gaaaaacagc atttgacttt aactctggct tccatatcgg aggaattaat
     1861 gccaacagtc ctcaattgat tgattcgatt gatgcttatc ctattccaaa aatcaaagag
     1921 tctgataaag accaaggaat tgaaacctca aacattccaa tggttgtttg gaaaaattca
     1981 aaacatccag aagttgctaa agcattctta gaagcacttt ataatgaaga agactacgtt
     2041 aaattccttg attcaactcc agtaggtatg ttgccaacta ttaaggggat tagcgattct
     2101 gcagcctata aagaaaatga aactcgtaag aaatttaaac atgctgaaga agtaattact
     2161 gaagctgtta aaaaaggtac tgctattggt tatgaaaatg gaccaagtgt acaagctggt
     2221 atgttgacta accaacacat tattgaacaa atgttccaag atatcattac aaatggaaca
     2281 gatcctatga aagcagcaaa agaagcagaa aaacaattaa acgatttatt tgaggctgtt
     2341 cagtagatgt aaaagactag aaaataggtg ggctagtgag ctgaaaagct ctagcccaat
     2401 cttgtaaaag aagggagaag gagaatggtt aaagaacgta atttaactcg ctggatattt
     2461 gttttgccag ctatgattat cgtaggatta ctctttgttt atccgttttt ctcgagtatt
     2521 ttttatagct ttaccaataa gcatttgatt atgcctaatt ataaatttgt tggtttggct
     2581 aactataaag ctgtgctatc agatcccaac ttctttaatg cgttctttaa ttcaattaag
     2641 tggaccgttt tctcattagt tggtcaagtt ttagtagggt ttgtattggc tttagctctt
     2701 cacagagtac gccacttcaa gaaattatat aggaccttat tgattgttcc ttgggcattt
     2761 cctaccatcg ttattgcctt ctcttggcag tggattctaa acggggttta tggctactta
     2821 cctaatctaa tcgtaaaatt aggtttaatg gaacatacac ctgcattttt gacagatagt
     2881 acatgggcat tcctatgttt ggtgtttatc aacatttggt ttggagcacc aatgattatg
     2941 gttaatgtgc tttcagcttt gcaaacagta ccagaagaac aatttgaggc tgctaagata
     3001 gatggtgctt caagttggca ggtgttcaag tttatcgtct ttccacatat taaagtggtt
     3061 gtaggacttc tagttgtttt gagaactgta tggatcttta ataactttga cattatctac
     3121 ctcattactg gtggtggacc agccaatgct acaacgacgc ttccaatttt tgcttacaac
     3181 ctgggttggg gaactaaatt gttgggtcgt gcttcagcag ttacagtatt gctctttatc
     3241 ttcttggtgg cgatttgctt tatctacttt gctatcatca gtaagtggga aaaggagggt
     3301 agaaaataat gaagaagaaa tccagtattt atttagatat tctctcacat gtacttttag
     3361 ttggtgcgac catcgttgca attttcccat tggtatggat tatcatatct tctgtcaaag
     3421 ggaaagggga attaactcag tatccaacac gattttggcc tgaacagttt acattagatt
     3481 atttcactca tgttatcaac gatttgcact tcattgataa cattcgaaac agtttaatca
     3541 ttgccttggc tacaaccctc attgcgatta ttatttctgc tatggcagcc tatggtattg
     3601 ttcgattctt tcctaaattg ggagcaatca tgtcgagact actcgtcatt acctacattt
     3661 tcccaccaat tttgttagca attccctatt caattgccat tgctaaagtt gggttaacaa
     3721 atagtttatt tggcttgatg atggtttatc tatcttttag tgttccatat gcagtttggc
     3781 tcttagttgg atttttccaa acagttccaa ttggaattga agaagcggct agaattgatg
     3841 gtgcaaataa atttgttacg ttttataaag ttgtgctacc gattgtagca ccaggtattg
     3901 tagcaacagc tatttataca tttatcaatg cttggaatga attcctgtat gccttgattt
     3961 tgattaacaa tacaggaaag atgacagtag cagtagccct tcgttcactt aatggttcag
     4021 aaatactaga ctggggagat atgatggcag cgtctgttat tgtagttctt ccatcaatta
     4081 ttttcttctc tatcatccaa aataagattg caagtggatt atcagaagga tctgtgaagt
     4141 agacgaaaga aggaaaaaaa tgaataaaag aggtctttat tcaaaactag gaatttctgt
     4201 tgtaggcatt agtcttttaa tgggagtccc cactttgatt catgcgaatg aattaaacta
     4261 tggtcaactg tccatatctc ctatttttca aggaggctca tatcaactga acaataagag
     4321 tatagatatc agccctttgt tattagataa attgtctgga gagagtcaga cagtagtaat
     4381 gaaatttaaa gcagatgaac caaactctct tcaagctttg tttggcctat ctaatagtaa
     4441 agcaggcttt aaaaataatt acttttcaat tttcatgaga gattctggtg agataggtgt
     4501 agaaataaga gacgcccaaa agggaataaa ttatttattt tccagaccag cttcattatg
     4561 gggaaaacat aaaggacagg cagttgaaaa tacactagta tttgtatctg attctaaaga
     4621 taaaacatac acaatgtatg ttaatggaat agaagtgttc tctgaaacag ttgatacatt
     4681 tttgccaatt tcaaatataa atggtataga taaggcaaca ctaggagctg ttaatcgtga
     4741 aggtaaggaa cattacctcg caaaaggaag tattggtgaa atcagtctat ttaacaaagc
     4801 aattagtgat caggaagttt caactattcc cttatcaaat ccatttcagt taattttcca
     4861 atcaggagat tctactcaag ctaactattt tagaataccg acactatata cattaagtag
     4921 tggaagagtt ctatcaagta ttgatgcacg ttatggtggg actcatgatt ctaaaagtaa
     4981 gattaatatt gccacttctt atagtgatga taatgggaaa acgtggagtg agccaatttt
     5041 tgctatgaag tttaatgact atgaggagca gttagtttac tggccacgag ataataaatt
     5101 aaagaatagt caaattagtg gaagtgcttc attcatagat tcatccattg ttgaagataa
     5161 aaaatctggg aaaacgatat tactagctga tgttatgcct gcgggtattg gaaataataa
     5221 tgcaaataaa gccgactcag gttttaaaga aataaatggt cattattatt taaaactaaa
     5281 gaagaatgga gataacgatt tccgttatac agttagagaa aatggtgtcg tttatgatga
     5341 aacaactaat aaacctacaa attatactat aaatgataag tatgaagttt tggagggagg
     5401 aaagtcttta acagtcgaac aatattcggt tgattttgat agtggctctt taagagaaaa
     5461 acataatgga aaacaggtcc ctatgaatgt tttctacaaa gattcgttat ttaaagtgac
     5521 tcctactaat tatatagcaa tgacaactag tcagaataga ggagagagtt gggaacaatt
     5581 taagttgttg cctccgttct taggagaaaa acataatgga acttacttat gtcccggaca
     5641 aggtttagca ttaaaatcaa gtaacagatt gatttttgca acatatacta gtggagaact
     5701 aacctatctc atttctgatg atagtggtca aacatggaag aaatcctcag cttcaattcc
     5761 gtttaaaaat gcaacagcag aagcacaaat ggttgaactg agagatggtg tgattagaac
     5821 attctttaga accactacag gtaagatagc ttatatgact agtagagatt ctggagaaac
     5881 atggtcggaa gtttcgtata ttgatggaat ccaacaaact tcatatggca cacaagtatc
     5941 tgcaattaaa tactctcaat taattgatgg aaaagaagca gtcattttga gtacaccaaa
     6001 ttctagaagt ggccgtaagg gaggtcaatt agttgtcggt ttagtcaata aagaagatga
     6061 tagtattgat tggaaatacc actatgatat tgatttgcct tcgtatggtt atgcctattc
     6121 tgcgattaca gaattgccaa atcatcacat aggtgtactg tttgaaaaat atgattcgtg
     6181 gtcgagaaat gaattgcatt taagcaatgt agttcagtat atagatttgg aaattaatga
     6241 tttaacaaaa taaaggagaa aaacatggtt aaatacggtg ttgttggagc agggtatttt
     6301 ggagctgaat tggctcgcta catgcaaaag aatgatggag cagagattac tcttctctat
     6361 gatccagata atgcagaggc gattgcagaa gaattgggag caaaagtagc aagttcctta
     6421 gatgagttgg tttctagcga tgaagtagat tgtgttatcg tcgcaactcc aaataatctt
     6481 cataaggaac cggttattaa ggctgcacag catggtaaaa atgttttctg tgaaaaacca
     6541 attgcgcttt cttatcaaga ttgtcgcgag atggtagatg cgtgtaaaga aaacaatgta
     6601 acctttatgg caggacatat tatgaatttc tttaatggtg ttcatcatgc aaaagaactc
     6661 attaatcaag gagttatcgg agacgttcta tattgtcata cagctcgtaa tggttgggaa
     6721 gaacaacaac cgtcagtatc atggaaaaaa attcgtgaaa aatcaggtgg tcacttgtat
     6781 caccacatcc atgaattgga ttgcgttcaa ttccttatgg ggggcatgcc tgaaactgta
     6841 accatgacag gtggaaatgt ggcccatgaa ggtgaacatt tcggtgatga agatgatatg
     6901 atttttgtca atatggaatt ttctaataag cgttttgctt tgttagaatg gggttcagct
     6961 tatcgttggg gtgaacatta tgtcttaatc caaggaagca aaggtgccat ccgcttagac
     7021 ttattcaact gtaaaggaac tcttaagcta gatgggcaag aaagctattt cttgattcac
     7081 gaatcgcaag aagaagatga tgatcggact cgtatctatc atagtacaga gatggatgga
     7141 gcaattgctt atggtaaacc aggtaaacgt actccattat ggctatcatc tgtcattgat
     7201 aaagaaatgc gctatctgca tgagattatg gaaggagctc cagtatcaga agaatttgca
     7261 aaacttttga caggtgaagc tgccctagaa gcaattgcta ctgcagatgc ttgtacccag
     7321 tctatgtttg aagatcgcaa agtaaaattg tcagaaattg taaaataaat tttggtattc
     7381 tcctatttat aggtcgactt gctcctctga aagtactttt agaggagctg tttgactttg
     7441 ctagtttttg aaactgaaat ctattatact acaaactatt gaaagcgttt taattttaag
     7501 gtataataat ctcatagaaa taaagaaaag gaggaaagag gatgccacag attagcaaag
     7561 aagccttgat tgagcaaatc aaagatggaa tcatcgtttc ttgtcaggct cttcctcatg
     7621 aaccgcttta tacagaagcg ggaggggtga ttcccttgct ggtcaaagcg gctgagcaag
     7681 gtggagcagt cggtatccga gcaaacagtg ttcgcgatat caaggaaatt aaggaagtca
     7741 ctaaacttcc aatcattggg attatcaaac gtgattatcc acctcaggaa cccttcatca
     7801 cggctactat gaaagaagtt gatgaattgg cagaactgga catcgaggtg attgctctgg
     7861 attgtaccaa gcgtgaacgc tacgatggtt tggaaattca agagttcatt cgtcaggtta
     7921 aggagaaata tcctaatcag cttttgatgg ctgatactag tatcttcgaa gaagggctag
     7981 cagctgtaga agcaggaatt gactttgtcg gaacaacctt atcaggctac acatcctaca
     8041 gtccaaaagt agacggtcca gattttgaat tgattaagaa actctgtgat gccggtgtag
     8101 atgtcattgc agaaggaaaa attcatacac cagaacaagc caaacaaatc cttgaatatg
     8161 gagtgcgagg catcgttgtt ggtggcgcca ttactagacc aaaagagatt acagaacgct
     8221 tcgttgctag tcttaaataa gatgtgaggg ggagttttat gtttaaagtt ttacaaaaag
     8281 ttggaaaagc ttttatgtta cctatagcta tacttcctgc agcaggtcta cttttgggga
     8341 ttggtggtgc actttcaaac ccaaccacga tagcaactta tccaatacta gacaatagta
     8401 tttttcaatc aatattccaa gtaatgagct ctgcaggaga ggttgtattc agtaatttgt
     8461 cactacttct ctgtgtggga ttatgtattg gcttagcgaa acgagataaa ggaaccgctg
     8521 cgttagcagg agtaactggt tacttagtta tgactgcaac gatcaaagct ttggtaaaac
     8581 tttttatggc agaaggatct gcaattgata ctggagttat tggagcatta gctgtcggaa
     8641 tagttgccgt atatttgcac aaccgatata acaatattca attaccttcc gctttaggat
     8701 tctttggagg ttcacgcttc gttcctattg ttacatcgtt ctcttctatc ttgattggct
     8761 ttgtcttctt tgttatttgg ccacctttcc aacaacttct tgtttctaca ggtggatata
     8821 tttctcaggc gggtccaatt ggaacttttc tatatggatt tttaatgaga ctttctggag
     8881 cagtaggctt acatcatata atttacccta tgttttggta tactgaactt ggtggtgttg
     8941 aaactattgc aggacaaaca gtggttggag ctcaaaaaat attttttgct caattagccg
     9001 atccggccca ttctggatta tttacagaag gaacaaggtt ttttgcaggt cgtttctcaa
     9061 caatgatgtt cggtttaccg gctgcctgtt tagcgatgta ccatagtgtt cctaaaaatc
     9121 gtcgtaaaaa atacgcgggt ttgttttttg gagttgcttt aacatctttt attaccggta
     9181 ttacagaacc aattgaattt atgtttctat tcgtcagtcc ggttctatat gttgttcacg
     9241 cattccttga tggtgttagc ttctttattg cagacgtctt aaatatttca ataggaaaca
     9301 cattttcagg aggtgtaatc gatttcactt tatttggaat tttgcagggg aacgctaaga
     9361 cgaattgggt tcttcagatt ccaattggac ttatttggag tgttttgtat tatattattt
     9421 ttagatggtt cattactcaa ttcaatgttc taacgccagg acgaggagaa gaagtagatt
     9481 ctaaagaaat ttctgaatcc gcagattcaa cttcaaatac tgcagattat ttaaaacagg
     9541 atagcctaca aattatcaga gccttgggtg gatcaaataa tatagaagat gtagatgctt
     9601 gtgtgacacg tttacgtgta gctgtaaaag aagttaatca agttgataaa gcacttttaa
     9661 aacaaattgg tgcagttgat gtcttagaag tgaagggtgg cattcaagca atctatggag
     9721 caaaagcaat cttatataaa aatagtatta atgaaatttt aggtgtagat gattaagtac
     9781 ttactgactt aataaaaaac agaggagagt gatggatgag taggatgaaa tgaaatcgca
     9841 tacaagaaat aaagaactca ttatccaagt tggatacgct tattacatag gagaatacaa
     9901 atgaaattta gaaaattagc ttgtacagta cttgcgggtg ctgcggttct tggtcttgct
     9961 gcttgtggca attctggcgg aagtaaagat gctgccaaat caggtggtga cggtgccaaa
    10021 acagaaatca cttggtgggc attcccagta tttacccaag aaaaaactgg tgacggtgtt
    10081 ggaacttatg aaaaatcaat catcgaagcg tttgaaaaag caaacccaga tataaaagtg
    10141 aaattggaaa ccatcgactt caagtcaggt cctgaaaaaa tcacaacagc catcgaagca
    10201 ggaacagctc cagacgtact ctttgatgca ccaggacgta tcatccaata cggtaaaaac
    10261 ggtaaattgg ctgagttgaa tgacctcttc acagatgaat ttgttaaaga tgtcaacaat
    10321 gaaaacatcg tacaagcaag taaagctgga gacaaggctt atatgtatcc gattagttct
    10381 gccccattct acatggcaat gaacaagaaa atgttagaag atgctggagt agcaaacctt
    10441 gtaaaagaag gttggacaac tgatgatttt gaaaaagtat tgaaagcact taaagacaag
    10501 ggttacacac caggttcatt gttcagttct ggtcaagggg gagaccaagg aacacgtgcc
    10561 tttatctcta acctttatag cggttctgta acagatgaaa aagttagcaa atatacaact
    10621 gatgatccta aattcgtcaa aggtcttgaa aaagcaacta gctggattaa agacaatttg
    10681 atcaataatg gttcacaatt tgacggtggg gcagatatcc aaaactttgc caatggtcaa
    10741 acatcttaca caatcctttg ggcaccagct caaaatggta tccaagctaa acttttagaa
    10801 gcaagtaagg tagaagtggt agaagtacca ttcccatcag acgaaggtaa gccagctctt
    10861 gaataccttg taaacgggtt tgcagtattc aacaataaag acgacaagaa agtcgctgca
    10921 tctaagaaat tcatccagtt tatcgcagat gacaaggagt ggggacctaa agacgtagtt
    10981 cgtacaggtg ctttcccagt ccgtacttca tttggaaaac tttatgaaga caaacgcatg
    11041 gaaacaatca gcggctggac tcaatactac tcaccatact acaacactat tgatggattt
    11101 gctgaaatga gaacactttg gttcccaatg ttgcaatctg tatcaaatgg tgacgaaaaa
    11161 ccagcagatg ctttgaaagc cttcactgaa aaagcgaacg aaacaatcaa aaaagctatg
    11221 aaacaatagt ccttagttat tctataaaaa gtagtttttt aaagaaccta agagtgtata
    11281 cccccttttc cctctacaca gatagtgtaa gaaaaggggg cttttgttta aaatgtaaga
    11341 aactgtcacg aaattaaaat gaagttctta cataagcgaa tcataaaaaa tttcattttg
    11401 attttaaaac agttcaagaa agtcaaaaaa ttattctatt tgaaagagag gtgccgactg
    11461 tgaaagtcaa taaaatccgt atgcgggaaa cagtgatttc ctacgctttc ctagcaccag
    11521 tattattctt ctttgtcatc tttgtgttgg ctccgatggt gatgggcttc attacaagtt
    11581 tctttaacta ctcaatgact aaatttgagt ttgtaggctt ggataactat atccgtatgt
    11641 ttaaagatcc tgtctttaca aaatctctga ttaacacagt tattttggtt attggatctg
    11701 taccagttgt tgttctattc tcactctttg tagcatctca gacctatcat caaaatgtca
    11761 ttgccagatc cttctaccgt ttcgtcttct tccttcctgt tgtaacgggt agtgttgccg
    11821 tgacagttgt ttggaaatgg atttatgacc cactatcagg gattctaaac tttgtcctta
    11881 agtccagcca catcatcagc caaaacattt cttggttggg agataaaaac tgggcattga
    11941 tggcgattat gattattctc ttgaccactt cagttggtca gcccatcatc ctttatatcg
    12001 ctgccatggg gaatattgac aattcactgg ttgaagcggc gcgtgttgat ggtgcaactg
    12061 agtttcaagt tttttggaag attaaatggc caagccttct tccaacaact ctttatattg
    12121 caatcatcac aacaattaac tcattccagt gttttgcctt gattcagctt ttgacatctg
    12181 gtggtccaaa ctactcaaca agtaccttga tgtactacct ttacgaaaaa gccttccaat
    12241 tgacagaata cggctatgcc aacacaattg gtgtcttctt ggcaatcatg attgctatcg
    12301 taagctttgt tcaatttaaa gtacttggaa acgacgtaga atactaaaga aaggagacag
    12361 ctatgcaatc tacagaaaaa aaaccattaa cagcctttac tgttatttca acaatcattt
    12421 tgctcttgtt gactgtgctg ttcatctttc cattctactg gattttgaca ggggcattca
    12481 aatcacaacc tgatacaatt gttattcctc ctcagtggtt ccctaaaatg ccaaccatgg
    12541 aaaacttcca acaactcatg gtgcagaacc ctgccttgca atggatgtgg aactcagtat
    12601 ttatctcatt ggtaaccatg ttcttagtct gtgcaacctc atctctagca ggttatgtat
    12661 tggctaaaaa acgtttctat ggtcaacgca ttctatttgc tatctttatc gctgctatgg
    12721 cgcttccaaa acaagttgtc cttgtaccat tggtacgtat cgtcaacttc atgggaatcc
    12781 acgatactct ctgggcagtt atcttgcctt tgattggatg gccattcggt gtcttcctca
    12841 tgaaacagtt cagtgaaaat atccctacag agttgcttga atcagctaaa atcgacggtt
    12901 gtggtgagat tcgtaccttc tggagtgtag ccttcccgat tgtgaaacca gggtttgcag
    12961 cccttgcaat ctttaccttc atcaatactt ggaatgacta cttcatgcaa ttggtaatgt
    13021 tgacttcacg taacaatttg accatctcac ttggggttgc gaccatgcag gctgaaatgg
    13081 caaccaacta tggtttgatt atggcaggag ctgcccttgc tgctgttcca atcgtcacag
    13141 tcttcctagt cttccaaaaa tccttcacac agggtattac tatgggagcg gtcaaaggat
    13201 aatactctga gaaaatctct tcaaactacg tcagcgtcac cttgccatac ttaagtattg
    13261 cctgcggtta gcttcctagt ttgttcttca attttcattg agtataggaa aatcaatcta
    13321 tcaagataca gaagtatatt ttatagattt agagaatata gaggttataa gtgtctacaa
    13381 aatggagggt atgcagttac tttatgaagt tttgtcagac acttataaac ttaagaatgg
    13441 ttttagttaa ctatcagaaa cgaaggaaag agtatgattt ttgacgattt gaaaaacatc
    13501 accttttaca aagggattca tcccaattta gacaaggcta tcgactatct ctaccaacat
    13561 cgtaaagatt cattcgaatt aggaaagtat gagattgatg gagataaagt ctttctagtt
    13621 gttcaggaaa atgtcctcaa tcaagttgag aataatcgat ttgaacacca taagaactat
    13681 gcagatttgc atttgctgat agaagggcat gaatattcga gctacggttc acgtatcaaa
    13741 gacgaggcag tagcattcga cgaagcgagt gacattggct ttgttcattg tcatgaacac
    13801 tacccactct tgttgggtta tcacaatttt gcgattttct tcccaggtga gccacatcag
    13861 ccaaatggtt atgcaggcat ggaagaaaag gttcgaaaat atctctttaa aattttgatt
    13921 gattaaaaat aggatgaatt gtttttttgt aaagctttga taatactcta ccatgaaatt
    13981 gatctttgtg aggtagagaa atgagaataa aatatttaaa aattggtatc ttctaagtat
    14041 gctgcaagag ctagtttctt agatggacag gggattacag ttgatgagat ggcttggata
    14101 attaggggca ttgtgactgc attgattggt agatacataa aattaggtac ttatgcagtt
    14161 aagtatggta ttagtatggc gcgctcgatc ttaagtaggg cagctgcaac tgcggcagca
    14221 agagtaggat tattgactaa gatttttgga tggattttac gaatagctgt gctcgcagct
    14281 gatgtatatg gtaattttgc caacaatatt gctgtagctt gggatgcaca tgataaaatc
    14341 cctaacaatg gtcgtataaa cttttaaaat gcgagaatga aagcactttg tattttttta
    14401 ttgtatatgt tagcttggac agtgcttgca atgataatcc gtggagggct agatggattt
    14461 gatgaacaca cttggcgtac tattttaatt gcttcgctgt ccgggatata tatagattat
    14521 atgtccatag ataaaagtag aaaaaagtcc aaaagaaaaa agaaaaaata gatttgttca
    14581 tggtagggac ttatgaaagc tttactgaca aaaaagaaaa cagtttacaa agaaaaatga
    14641 tggaggagca aacatggcac aaaaaggagt aagccttatc aaggcagcat ttgatacaga
    14701 taactttctc atgcgtttta gtgagaaagt cttggacatc gtgacagcca atcttctttt
    14761 tgtcgtctct tgtttgccca tcgtgacgat tggagtggct aaaatcagcc tctacgagac
    14821 catgttcgaa gttaagaaga gcagacgggt gcctgttttt aaaatctatc taagatcttt
    14881 caagcaaaat ctgaaactag gtcttcagct gggtttaatg gagttaggaa ttgtgtttct
    14941 taccctttca gatctctatc ttttctgggg tcaaacagct ctgcccttcc aattgctgaa
    15001 agccatttgt ctaggcattc tgattttcct tacgattgtg atgttggcta gctatccaat
    15061 cgcggcacgt tatgatttaa cttggaaaga agtgttacaa aaagggctta tcttggctag
    15121 ttttaacttt ccttggttct tcctcatgtt agccattctt gtcctcattg tgatggttct
    15181 ttatctgtcc gccttcagtc tactcttagg tggctcagtc ttcctacttt ttgggtttgg
    15241 actattggtc tttatccaga ctggattgat ggagaaaatt ttcgcaaaat accaatagga
    15301 gccttatttc tgaaactact ttcaaaggct ccaaacgcta ttctataagc gagaaactaa
    15361 aatctaagtg tctataagat attgaaagcc ttttcggtaa agtgtatact aaagaagtaa
    15421 agaaaaatct gctttagcag aaaataaaaa taataggaga aaatctatgt cagatttgaa
    15481 aaaatacgaa ggtgtcattc cagccttcta cgcatgttat gatgagcaag gagaagtaag
    15541 tccagagcgt acgcgtgcct tggttcaata cttcattgat aaaggtgttc aaggtcttta
    15601 tgtcaatggt tcttctggtg aatgtatcta ccaaagcgtt gaagatcgca agttgatttt
    15661 ggaagaagtc atggcggtag ccaaaggtaa attgaccatt attgcccatg ttgcttgcaa
    15721 taatactaaa gatagtatgg aacttgctcg ccatgctgaa agcttgggag tagatgctat
    15781 tgcaacgatt ccaccaattt acttccgctt gccagaatac tcagttgcca aatactggaa
    15841 cgatattagt tctgcagctc caaacacaga ctacgtgatt tacaacattc ctcaattggc
    15901 aggggttgct ttgacttcaa gcctttacac agaaatgttg aaaaatcctc gtgttatcgg
    15961 tgttaagaac tcttcaatgc cagttcaaga tatccaaacc tttgtcagcc ttggcgggga
    16021 agaccatatt gtctttaacg gtccagatga acagttccta ggtggccgcc tcatgggtgc
    16081 taaggctggt atcggtggta cttatggtgc tatgccagaa ctcttcttga aactcaatca
    16141 gttgattgcg gataaagatt tagaaacagc gcgtgaattg cagtatgcta tcaacgcaat
    16201 cattggtaaa ctcactgctg cacatggaaa tatgtacggt gtcatcaaag aagttttgaa
    16261 gatcaatgaa ggcttgaata ttggttctgt tcgttcacca ttgacaccag tgactgaaga
    16321 cgatcgtcca gttgtagaag cggctgcagc cttgattcgt gaaaccaagg agcgcttcct
    16381 ctaatctaaa aggaggtatt tatgacatac tacgttgcaa ttgatatcgg tggaactaac
    16441 atcaagtatg gtttggttga tcaagagggg caacttcttg aatcacatga aatgccaaca
    16501 gaggcgcata agggtggacc tcatatctta caaaagacca aagatatcgt agctagttat
    16561 ttagaaaaag gcccagtagc aggtgttgcc atatcttctg ctgggatggt ggatccggat
    16621 aagggtgaga ttttctatgc tgggccgcaa atccctaact acgcaggcac ccagttcaaa
    16681 aaggaaatcg aagaaagctt tactattcct tgtgagattg aaaatgatgt caactgtgca
    16741 ggtcttgctg aggcagtatc tggttcaggc aagggagcaa gtgtgacact ttgcttgacc
    16801 attggaaccg gtatcggtgg ttgcttgatt atggatagga aagtcttcca tggttttagt
    16861 aattcagcct gtgaagtcgg gtatatgcat atgcaggatg gagcttttca ggatctcgct
    16921 tctacaacag ctttagtgaa atatgtagct gaagcccatg gagaagatgt tgatcagtgg
    16981 aatggccgac gtatctttaa ggaagctact gaaggaaaca aaatctgcat ggaaggtatt
    17041 gaccgtatgg ttgactatct aggaaaaggt ctggcaaata tttgctacgt tgccaatcca
    17101 gaagtggtca ttcttggtgg tggtatcatg gggcaagagg ctatcctcaa acctaagatc
    17161 cgcacagcct tgaaagaggc tttggtacca agtttagcag aaaaaacacg attagaattt
    17221 gcccatcacc aaaatacagc agggatgttg ggtgcatatt atcattttaa gacaaaacaa
    17281 tcctagtttg gctcagccaa actaggattt tcttacacgt ttttgtctac gatagccgtt
    17341 gagtttttta ttttcccagt agctattaaa gattttttcc ttgctttcgc gattgatttc
    17401 caaaaagtag gcataaatca aatcgataaa gaagagcata ggaagttgag cggatattcg
    17461 ttggatatag gagggttggc tgtgggtggc tacaagaaca gtctctgtat aggtctggct
    17521 atttttattg ggaacacttg taaagagtac agtctttgcc cccatctcct tggcatctaa
    17581 tagactatct aaaatagaag gagttgagcc tgaaagtgag aagcccagta ctagacaatt
    17641 ttcatccatg atgctggttg tccaggcaaa gccgtcttgg tctgtcaaag cttcgcagac
    17701 cacacctaat cgcataaaac gtaatttcat ttcacgggcg acgaggccag aactccctgt
    17761 tccaaagaag tagatacgct cagcatcttc gattagctgg gcaattcgtt ctagttggat
    17821 ttcgtcaatc aagtcttgtg tttgttccct catattgcta taacttctga ggactcgttt
    17881 ggtcagtgga ctgtgcttgg aaacttggtt ggcttgattt tctgcctgat gttggtattg
    17941 gaaaataaat tctcggtagc cagtaaagcc acacttttta gcaaagcggg tcaaagcagc
    18001 ttgagaaata tgtaattttt gggtgacttg ttgagaagat aaatcatctg taatcgtttc
    18061 agcttgcaaa aaatagcgag cgatttcttg ctctaggtct gtcatttctt caaaatgtga
    18121 atcaatgata gttgcgatat ctggtttgtc catagggaaa gctcctttac atgagtcata
    18181 ctggaagact agatcaggga atagtcacac ttcattataa cacataatat aaggatagat
    18241 aaataaaaac gcatctctgt tttaaaaacg aaaaaatcga aaaagcttct ctcttttcca
    18301 taattttcta ctcaaattgt ggtacaatta agagtaagat tttaagttag aaatgagact
    18361 gatttgtatg agaaaattta acagccattc gattccgatt cggcttaatt tattgttttc
    18421 aatcgtcatt ttactcttta tgaccattat tggtcgtttg ttgtatatgc aggttttgaa
    18481 caaggatttt tacgaaaaaa agctagcctc agctagtcag accaagatta caagcagttc
    18541 agcccgtggg gaaatttatg atgctagtgg aaaacctttg gtagaaaata cgttaaagca
    18601 ggttgtttcc tttacgcgta gcaataaaat gacggctaca gacttaaaag aaacagctaa
    18661 aaagttactg acttatgtga gcatcagttc tccaaatttg acagaacgcc agctggcgga
    18721 ttactatttg gctgatcctg aaatctataa aaaaatagtg gaagctctcc caagcgagaa
    18781 acgcttggat tcagatggca atcgtctatc cgaatcagaa ctgtataaca atgcggtcga
    18841 tagtgtacaa acgagtcaac taaactatac agaggatgaa aagaaagaaa tctatctttt
    18901 tagtcagtta aatgctgttg gaaactttgc gacaggaacc attgctacag atcctctaaa
    18961 tgattctcag gtggctgtta ttgcctctat ttcaaaggag atgcctggca ttagtatttc
    19021 tacttcttgg gatagaaagg ttttggaaac ttccctttct tctatagttg ggagtgtatc
    19081 cagtgaaaaa gctggtctcc cagcggaaga agcagaagcc tatcttaaaa aaggctattc
    19141 tctaaatgat cgtgtaggaa cctcctattt ggaaaagcaa tatgaagaga ccttacaagg
    19201 aaaacgctcg gtaaaagaaa tccatctgga taaatatggc aatatggaaa gcgtggatac
    19261 aattgaggaa ggtagtaagg gaaacaatat caaactgacc attgatttgg ctttccaaga
    19321 tagcgtggat gctttactga aaagttattt caattctgag ctagaaaatg gtggagccaa
    19381 gtattctgaa ggtgtctatg cagtcgccct taacccaaaa acaggtgcgg ttttgtctat
    19441 gtcagggatt aaacatgact tgaaaacggg agagttgacg cctgattcct tgggaacggt
    19501 aaccaatgtc tttgttccag gttcggttgt caaggcggcg accatcagct caggttggga
    19561 aaatggagtc ttgtcaggaa accagacctt gacagaccag tccattgtct tccaaggttc
    19621 agctcccatc aattcttggt atactcaggc ttacggttca ttccctatca cagcggtcca
    19681 agctctggag tattcatcaa atacctatat ggtccaaaca gccttaggtc ttatggggca
    19741 aacctatcaa cccaatatgt ttgtcggcac cagcaatcta gagtctgcta tggagaaact
    19801 gcgttcaacc tttggcgaat atggcttggg tactgcgaca ggaattgacc taccagatga
    19861 atctactgga tttgttccca aagagtatag ctttgctaat tacattacta atgcctttgg
    19921 gcagtttgat aactatacgc cgatgcagtt ggctcagtat gtagcaacta ttgcaaataa
    19981 tggtgttcgt gtggctcctc gtattgttga aggcatttat ggtaataatg ataagggagg
    20041 actgggtgac ttgattcagc aactgcaacc gacagagatg aataaggtca atatatccga
    20101 ctccgatatg agcatcttgc accaaggttt ttatcaggtt gcccatggta ctagtggatt
    20161 gacaactgga cgtgcctttt caaatggtgc cttggtatcc attagcggaa aaacaggtac
    20221 agccgaaagc tatgtggcag atggtcagca agcaaccaat accaatgcgg tggcctatgc
    20281 cccatctgat aatccccaaa tcgctgtcgc agtggtcttt cctcataata ccaatctaac
    20341 aaatggtgta ggaccttcca ttgcgcgtga cattatcaat ctgtatcaaa aataccatcc
    20401 aatgaactag aaaggaaatt atgctttatc caacacctat tgccaagttg attgacagtt
    20461 attctaagtt accaggtatc gggattaaga cggctacgcg tctggccttt tatacgattg
    20521 ggatgtctgc tgatgatgtc aatgaatttg caaaaaatct cctttctgct aagagagaat
    20581 tgacatattg ttctatttgt ggacgtttga cagacgacga tccttgttct atctgtactg
    20641 attcgactcg tgaccagaca acaattttag ttcttgagga tagtagagat gtggcagcca
    20701 tggaaaatat ccaagaatac catggactct atcatgtcct gcatggcctc atttctccta
    20761 tgaatggtat cagtccggac gatatcaatc ttaagagcct tatgactcgt cttatggata
    20821 gtgaggtttc agaagtgatt gtggcgacta atgctacagc ggatggtgaa gcgacctcca
    20881 tgtatctttc acgtttgctc aagccggctg gtatcaaggt tacgcgtcta gcacgaggtc
    20941 tcgctgtggg agcggacatt gagtatgcgg acgaagtgac actcttacga gcgattgaaa
    21001 atcggacaga gttgtaagtg taggcaaatt tacgaactcc attcatttat aaaaaatcaa
    21061 agaggctgaa aatcgttcct atcggcctct ttttgtatag tgtgatgagt agaatcaggt
    21121 tcaagtttta aaaaaccaag caaatatgat atactaaaga gcgagtattc tagtagaatt
    21181 aggacaaata atatgaaaca aacgattatt cttttatatg gtggacggag tgcggaacgc
    21241 gaagtctctg tcctttcagc tgagagtgtc atgcgtgcgg tcaattacga ccgtttcaca
    21301 gtcaagactt tctttatcag tcagtcaggt gactctatca aaacgcagga atttagtcat
    21361 gctccggggc aagaagaccg tctcatgacc aatgaaacca ttgattggga taagaaagtt
    21421 gcaccaagtg ctatctacga agaaggtgca gtggtctttc cagtccttca cgggccaatg
    21481 ggagaagatg gctctgttca aggattcttg gaagttttga aaatgcctta cgttggttgc
    21541 aacattttgt catcaagtct tgccatggat aaaatcacga ctaagcgtgt tctggaatct
    21601 gctggtattg cccaagttcc ttatgtggct atcgttgaag gcgatgatgt gactgctaaa
    21661 atagctgaag tggaagaaaa attggcttat ccagtcttca ctaagccgtc aaacatgggg
    21721 tctagtgtcg gtatttctaa gtctgaaaac caagaagaac tccgtcaagc cttaaaactt
    21781 gccttccgat atgacagccg tgtcttggtt gagcaaggag tgaatgcccg tgaaattgag
    21841 gttggcctct tgggtaacta cgatgtcaag agcacgctac ctggagaagt tgtcaaggac
    21901 gttgcctttt atgactacga tgccaagtat attgataaca aggttactat ggatattcct
    21961 gccaaaatca gtgatgatgt ggtggctgtc atgcgtcaaa atgcagaaac agccttccgt
    22021 gccattggtg gccttggtct atctcgttgc gatttcttct atacagataa gggagagatt
    22081 tttctcaacg agctcaatac catgccaggt ttcacccagt ggtctatgta cccactactt
    22141 tgggaaaata tggggatcag ctacccagaa ctaatcgagc gtttggttga ccttgccaag
    22201 gaaagttttg acaagcgcga agcgcatttg atataaaatg aaagagaggg tagaagccag
    22261 aaccatcact gcaaggtgac tagagttctc ggacttcagc cctttttaaa ggagtagaaa
    22321 tgaaattaac aatccatgaa attgcccaag ttgttggagc caaaaatgat atcagtatct
    22381 ttgaggacac tcagttagaa aaagctgagt ttgatagtcg tttgattgga actggagatt
    22441 tatttgtgcc acttaaaggt gcgcgtgatg gccatgactt tattgaaaca gcctttgaaa
    22501 atggtgcagc agtaaccttg tctgagaaag aggtctcaaa tcatccttac attttagtag
    22561 atgatgtttt gacagccttt caatccctag catcctacta tcttgaaaaa acgactgttg
    22621 atgtctttgc tgttacaggt tcaaatggca agacaacgac taaggatatg ttggcgcatt
    22681 tactgtcaac aagatacaag acctacaaaa cacaaggcaa ttacaataat gagattggcc
    22741 ttccttacac agttcttcat atgcctgaag gaacagaaaa gttggttttg gagatgggac
    22801 aggatcactt gggagatatt catctcttgt ctgaattggc tcgtccaaaa acagccatcg
    22861 tgaccttggt tggagaagct catttggcct ttttcaaaga tcgttctgag attgctaaag
    22921 gaaaaatgca aattgcagac ggaatggctt caggttcctt gcttttagcg ccggctgacc
    22981 ctatcgtaga ggactatttg ccaattgata aaaaggtggt tcgttttggt caaggagcag
    23041 agctggaaat tactgacttg gttgagcgta aggacagtct gacctttaag gctaatttct
    23101 tggaacaagc ccttgatttg ccagtaactg gcaagtacaa tgcgacaaat gctatgattg
    23161 catcctatgt tgccttgcaa gaaggagttt cagaggagca aattcgtttg gcattccaac
    23221 atcttgaatt gacgcgtaac cgtaccgagt ggaagaaagc agccaatgga gcagatatcc
    23281 tgtcagatgt ttacaatgcc aatccaactg ctatgaaact gattttagag actttctctg
    23341 ccattccagc caatgaaggt ggcaagaaaa ttgcagtgtt ggcggatatg aaggagcttg
    23401 gtgaccagtc tgttcaactt cataatcaga tgattttgag cctctcccca gatgtgcttg
    23461 atatcgttat tttctatgga gaagatattg ctcagttggc tcaattggcc agtcaaatgt
    23521 ttccaatcgg ccacgtttac tacttcaaga aaacagaaga ccaggatcaa tttgaagacc
    23581 tagtcaagca ggttaaggaa agccttggag cctatgacca aatcttgcta aaaggttcta
    23641 actctatgaa tctagccaaa ttggtagaaa gtttagaaaa tgaatgcaag tgattttgct
    23701 aagtatcttc aaagaatgat tgctcttaca gatactggac taacctttac aaaggatccg
    23761 tttgaccgtg agcgctacga agacttgcga agtctgttat ctgaaatgtt gaatcaggta
    23821 tcagaccttg atgcagacga agtggcagaa ctcttgaaac cgacctccgc ttatgcgact
    23881 cctttaatgg acgtccgtgc ttggatagtt gaggatgaaa aaatttgtct ggttagggga
    23941 caaggagaga atgattgggc tttgccaggt ggctttggcg aggtcggtta ttcaccaact
    24001 gaaaatattc tcaaggaaat tgaagaagaa accggtttta aagccaaagt tgaacgacta
    24061 ctagctgttt ttgataccaa tcgtttccaa ctacagagca aacaatatgc aaagtttgtt
    24121 tttgaatgta agcttctcga tggacaattt caagaaaatc aagaaatcgc tgaccttcaa
    24181 ttttttgcaa ttgaccaact gccgaattta tctgaaaaac gcattaccaa ggagcaaata
    24241 gagcttcttt ggcaggttta tcaaggtcat agggggcaat atcttgacta agaagatgat
    24301 tatcgtattt ctaaatccat ttttaacaac tagcatggta taataatatg caggaaaatt
    24361 ttgaattatg aggaagacta gatgaattta tgggatattt tctttacgac tcaggcaacc
    24421 gagccgccca aatttgacct tttttggtat gttagcctat ttacgctctt agccttaacc
    24481 ttttatacag cccatcgcta tcgtgaaaat aaggtttacc aacgattttt ccaaatcttg
    24541 cagactgttc agttaatcct tctttatggt tggtactggg tcaatcatat gccactgtca
    24601 gaaagcctac ccttttacca ttgccgtatg gctatgtttg tggtactctt gcttcctggt
    24661 caatccaaat ataaacaata ctttgcatta ttgggaacat ttgggacatt agcagccttt
    24721 gtttatccag tgccagatgc ttaccctttt ccacatatca ccattctatc ctttatcttt
    24781 ggtcatttag cactcttggg gaactctcta gtttatctat tgagacagta taatgcgcga
    24841 ttgctggatg tgaagggaat ttttctcatg acctttgccc taaatgcctt gatttttgtg
    24901 gtcaatttgg tgacaggtgg cgattacgga tttttgacaa aaccgccatt ggttggggat
    24961 cacggtctag tagctaatta tttacttgtt tcaattgtgc tggtagctac tatcagtttg
    25021 actaagaaaa tcttagaatt ctttttagct caagaagcag aaaaaatgat tgcaaaggaa
    25081 gcttaacaca gagctttctt ttttgctctt agagagtttt tacaagcagc ttataaaata
    25141 agaatttctg aatagacaaa ctcaaaaaat ggctgggaaa tttaggaaaa aagcaagcac
    25201 gattaaattt tttgtgttat aatattttgt gaatagctat gcctatgttt agctatggaa
    25261 taatacgaag tgcgaaactt ggaagataga gaggaagcga tgtaatggct agagaaggct
    25321 tttttacagg tctagatatt ggaacaagct ctgtcaaggt gcttgtggcc gagcagagaa
    25381 atggtgaatt aaatgtaatt ggcgtgagta atgccaaaag taaaggtgta aaggatggaa
    25441 ttattgttga tattgatgca gcagcaactg ctatcaagtc agccatttcc caagcggaag
    25501 aaaaggcagg catttcgatt aaatcagtga atgtcggctt gcctggtaat cttttgcagg
    25561 tagaaccaac tcaggggatg attccagtaa catctgatac taaggaaatt acggatcaag
    25621 atgttgaaaa tgttgtcaaa tcagctttga caaagagtat gacacctgac cgtgaagtca
    25681 ttacctttat tcctgaagaa tttattgtgg atggtttcca agggattcgt gacccacgtg
    25741 gcatgatggg ggttcgcctt gaaatgcgtg gtttgcttta tacaggacct cgtactatct
    25801 tgcacaattt gcgtaagacg gttgagcgtg caggtgttca ggttgaaaat gttatcattt
    25861 caccactagc aatggttcag tctgttttga acgaagggga acgtgaattt ggtgctacag
    25921 tgattgatat gggggcaggt caaacgactg tcgctacaat ccgtaatcaa gaactccagt
    25981 tcacacatat tctccaagaa ggtggagatt atgtaactaa agatatctcc aaggttttga
    26041 aaacctctcg caaattagcg gaaggcttaa aactgaatta cggggaagcc tatccgcctc
    26101 ttgcaagcaa agaaaccttc caagtagagg ttattggaga agtagaagca gtcgaagtga
    26161 cggaagccta cttgtcagaa attatttctg cacgaatcaa gcacatcctt gaacaaatca
    26221 agcaagaatt agatagaagg cgtctattgg acctccctgg tggtattgtc ttaatcggtg
    26281 ggaatgccat tttaccaggt atggttgagc ttgctcagga agtctttggc gtccgtgtca
    26341 agctttatgt tccaaatcaa gttggtatcc gtaatccagc ctttgcgcat gtgattagtt
    26401 tatcagaatt tgcgggtcaa ttaacagaag ttaatctttt ggctcaggga gcgataaaag
    26461 gtgagaatga cttaagtcat cagccaatta gttttggtgg gatgctgcaa aaaacagctc
    26521 agtttgtaca atcaacgcct gttcaaccag ctcctgctcc agaagtagag ccggtggcgc
    26581 ctacagaacc aatggcggat ttccaacaag cttcacaaaa taaaccgaaa ttagcagatc
    26641 gtttccgtgg cttgatcgga agcatgtttg acgaataaag aggaaaaata aattatgaca
    26701 ttttcatttg atacagctgc tgctcaaggg gcagtgatta aagtaattgg tgtcggtgga
    26761 ggtggtggca atgccatcaa ccgtatggtc gacgaaggtg ttacaggcgt agaatttatc
    26821 gcagcaaaca cagatgtaca agcattgagt agtacaaaag ctgagactgt tattcagttg
    26881 ggacctaaat tgactcgtgg tttgggtgca ggaggtcaac ctgaggttgg tcgtaaagcc
    26941 gctgaagaaa gcgaagaaac actgacggaa gctattagtg gtgccgatat ggtcttcatc
    27001 actgctggta tgggaggagg ctctggaact ggagctgctc ctgttattgc tcgtatcgcc
    27061 aaagatttag gtgcgcttac agttggtgtt gtaacacgtc cctttggttt tgaaggaagt
    27121 aagcgtggac aatttgctgt agaaggaatc aatcaacttc gtgagcatgt agacactcta
    27181 ttgattatct caaacaacaa tttgcttgaa attgttgata agaaaacacc gcttttggag
    27241 gctcttagcg aagcggataa cgttcttcgt caaggtgttc aagggattac cgatttgatt
    27301 accaatccag gattgattaa ccttgacttt gccgatgtga aaacggtaat ggcaaacaaa
    27361 gggaatgctc ttatgggtat tggtatcggt agtggagaag aacgtgtggt agaagcggca
    27421 cgtaaggcaa tctattcacc acttcttgaa acaactattg acggtgctga ggatgttatc
    27481 gtcaacgtta ctggtggtct tgacttaacc ttgattgagg cagaagaggc ttcacaaatt
    27541 gtgaaccagg cagcaggtca aggagtgaac atctggctcg gtacttcaat tgatgaaagt
    27601 atgcgtgatg aaattcgtgt aacagttgtc gcaacgggtg ttcgtcaaga ccgcgtagaa
    27661 aaggttgtgg ctccacaagc tagatctgct actaactacc gtgagacagt gaaaccagct
    27721 cattcacatg gctttgatcg tcattttgat atggcagaaa cagttgaatt gccaaaacaa
    27781 aatccacgtc gtttggaacc aactcaggca tctgcttttg gtgattggga tcttcgccgt
    27841 gaatcgattg ttcgtacaac agattcagtc gtttctccag tcgagcgctt tgaagcccca
    27901 atttcacaag atgaagatga attggataca cctccatttt tcaaaaatcg ttaagtaaat
    27961 gaatgtaaaa gaaaatacag aacttgtttt tcgagaagtt gcagaggcta gtctgagtgc
    28021 tcatcgagag agtggttcgg tctctgtcat tgcagttacc aagtatgtag atgtaccgac
    28081 agcggaagcc ttgcttccgc taggtgttca tcatatcggt gaaaatcgtg tagataagtt
    28141 tctggaaaaa tatgaagctt taaaagatcg agatgtgact tggcatttga ttggtacctt
    28201 gcaaagacgt aaggtgaaag atgtcattca atacgttgat tatttccatg cattggactc
    28261 agtaaagcta gcaggggaaa ttcaaaaaag aagtgaccga gtcatcaagt gtttccttca
    28321 agtaaatatt tctaaagaag aaagcaaaca cggtttttcg agagaggaac tgctggaaat
    28381 cttgccagag ttagccggac tagataagat tgaatatgtt ggtttaatga cgatggcacc
    28441 ttttgaggct agcagtgagc agttgaaaga gattttcaag gcggcccaag atttacaaag
    28501 agaaattcaa gagaaacaaa ttccaaatat acctatgacc gagttaagta tgggaatgag
    28561 tcgtgattat aaagaagcga ttcaattcgg ttccactttt gttcgtatag gtacatcatt
    28621 ttttaagtag gagagaacca tgtctttaaa agatagattc gatagattta tagattattt
    28681 tacggaggat gaggattcaa gtctccctta tgaaaaaaga gatgagcctg tgtttacttc
    28741 agtaaattct tcacaggaac cggctctccc aatgaatcaa ccttcacagt cggctggtac
    28801 aaaagagaac aatatcacca gacttcatgc aagacaacag gaattggcaa atcagagtca
    28861 gcgtgcaacg gataaggtca ttatagatgt tcgttatcct agaaaatatg aggatgcaac
    28921 agaaattgtt gatttattgg caggaaacga aagtatcttg attgattttc agtatatgac
    28981 agaggtgcag gctcgtcgtt gtttggacta tttggatgga gcttgtcatg ttttagctgg
    29041 aaatttgaaa aaggtagctt ctaccatgta tttgttaaca ccagtgaacg ttattgtaaa
    29101 tgttgaagat atccgtttac cagatgaaga tcaacagggt gagttcggtt ttgatatgaa
    29161 gcgaaataga gtacgataat gattttttta attcgtatga tttataatgc agtggatatt
    29221 tactccctga ttttgatagc cttcgctgtc atgtcttggt ttccaggtgc ctacgaatcc
    29281 agtttaggtc gttggattgt agcgttggtg aaaccagtgc ttgctccctt gcaacgcctg
    29341 cctttacaga tagcgggtct tgatttatct gtttgggttg cgattgtttt ggttcgattt
    29401 ttaggagaaa acttagtgcg ttttctggcg atgataggat gaataaaggg atttatcagc
    29461 atttctccat agaagatcgt ccatttcttg acaagggaat ggaatggata aagaaggtag
    29521 aagatagcta tgctcctttt ttaactcctt ttatcaatcc tcatcaggag aagctattaa
    29581 agattttggc aaaaacctat ggtcttgctt gtagcagtag tggggaattc gtctcgagtg
    29641 agtatgttcg agttttatta tacccagatt atttccaacc agagttttca gattttgaaa
    29701 tatctcttca ggaaattgtg tattccaata aatttgaaca tttaacgcat gctaagattt
    29761 tagggacagt catcaatcaa ttagggattg aacggaaact ttttggagat atcctagtag
    29821 atgaagaacg ggcgcagatt atgattaatc agcagtttct tcttctcttt caagatggac
    29881 taaagaaaat tggtcgtata cctgtttcgc tggaggaacg tcctttcacc gagaaaatag
    29941 ataagctaga acagtatcga gaactggatt tatctgtgtc tagttttcga ttagatgttc
    30001 ttttatcaaa tgttttgaaa ctatctagga atcaagcaaa ccagttgatt gaaaagaaac
    30061 ttgtccaagt aaattatcat gtggtagaca aatcagatta cactgttcaa gttggagact
    30121 tgattagtgt gagaaaattt ggtcgcttga gattacttca agataaggga caaacgaaaa
    30181 aagagaagaa aaaaataacc gtccagttat tattaagtaa gtgaggaata gaatgccaat
    30241 tacatcatta gaaataaagg acaagacttt tggaactcga ttcagaggtt ttgatccaga
    30301 agaagtcgat gaatttttag atattgtggt tcgtgattac gaagatcttg tgcgtgcgaa
    30361 tcatgataaa aatttgcgta ttaagagttt agaagagcgt ttgtcttact ttgatgaaat
    30421 aaaagattca ttgagccagt ctgtattgat tgctcaggat acagctgaga gagtgaaaca
    30481 ggcggcgcat gaacgttcaa acaatatcat tcatcaagca gagcaagatg cgcaacgctt
    30541 gttggaagaa gctaaatata aggcaaacga gattcttcgt caagcaactg ataatgctaa
    30601 gaaagtcgct gttgaaacag aagaattgaa gaacaagagc cgtgtcttcc accaacgtct
    30661 caaatctaca attgagagtc agttggctat tgttgaatct tcagattggg aagatattct
    30721 ccgtccaaca gctacttatc ttcaaaccag tgatgaagcc tttaaagaag tggttagcga
    30781 agtacttgga gaaccgattc cagctccaat tgaagaagaa ccaattgata tgacacgtca
    30841 gttctctcaa gcagaaatgg aagaattaca agctcgtatt gaggtagccg ataaagaatt
    30901 gtctgaattt gaagctcaga ttaaacagga agtggaaact ccaactcctg tagtgagtcc
    30961 tcaagttgaa gaagagcctc tgctcatcca gttggcccaa tgtatgaaga accagaagta
    31021 gctccagtgc atccgacagg tccaacacca gctacagaaa ctgttgattc agcaccagga
    31081 tttgaagcac cgcaagaatc cgttacaatt ttataagaaa cgatgtgaga acaatatctt
    31141 atccttatat ttccagcgag caggagatgg tgtgagtcct gcattcccta acgataagat
    31201 tatcctctca aaaactcaag tctgaagcta gtaagatttg acgtttccca cgttacggga
    31261 taagagggag aaagactaaa tctttttccg aataaaggtg gtaccacgat tttcgtcctt
    31321 tttggaagtc gtggttttta atttgttatt atttataaag gagataccat gaaactcaaa
    31381 gataccctta atcttgggaa aacagctttc ccaatgcgtg caggccttcc gaccaaagag
    31441 ccagtttggc aaaaggaatg ggaagatgca aaactttacc aacgtcgtca agaactaaat
    31501 gaagggaaac cgcattttgt cttgcatgat ggccctccat acgcaaacgg aaatatccac
    31561 gttggacatg ccatgaatca tatctcaaaa gatatcatca ttcgttctaa gtctatgtca
    31621 ggttttaacg caccttatat cccaggttgg gatactcatg gtctgccaat cgagcaagtt
    31681 ttggcaaagc aaggtgtgaa gcgcaaagaa atggacttgg ttgagtactt gaaactctgt
    31741 cgtgagtacg ctctttctca agtttataaa caacgtgatg atttcaaacg cttggggatg
    31801 tcaggtgact gggaaaattt atatgtgact ttaactccag actatgaagc agcccaaatc
    31861 cgtgtctttg gtgagatggc taataagggt tatatctacc gtggtgccaa gccagtttac
    31921 tggtcatggt catctgagtc agcccttgcc gaagcggaaa ttgaatacca tgatttggtt
    31981 tcgacttcac tttattatgc caataaggta aaagatggca aaggtatcct agatacagat
    32041 acttatatcg tagtctggac aacaactcca tttaccatca cagcttctcg tggtttgact
    32101 gttggtgcag atattgatta cgttttggtt caacctgcta gtgaaactcg taagtttgtc
    32161 gttgctgcag aattgttgac tagcttgtct gagaaatttg gctgggctga tgttcaagtg
    32221 ttggcaactt accgtggtca agaactcaac cacatcgtaa cagaacaccc atgggataca
    32281 gctgtagatg agttggtaat ccttggtgat cacgttacca ctgactctgg tacaggtatc
    32341 gtccatacag cccctggttt tggtgaggac gactacaatg ttggtattgc taatggtctt
    32401 gaagtcgcag tgactgttga cgaacgcggt atcatgatgg cgaatgctgg tcctgagttt
    32461 gaaggtcagt tctacgacaa ggttgtacca actgttattg aaaaacttgg taacctcctt
    32521 ctagcccaag aagaaatctc tcactcatac ccatttgact ggcgtactaa gaaaccaatc
    32581 atctggcgtg cagttccaca atggtttgcc tcagtttcaa aattccgcca agaaatcttg
    32641 gatgctattg ataaagttaa attccataca gaatggggta aagtacgtct atataatatg
    32701 attcgtgacc gtggtgactg ggttatctct cgtcaacgtg cttggggtgt tccacttcca
    32761 atcttctatg cagaagacgg tacagctatc atgacagctg agactattga acatgtggcg
    32821 caactctttg aagtacatgg ttcaagcatt tggtgggaac gtgatgccaa agacctctta
    32881 ccagaaggat ttacacatcc aggttctcca aatggggagt tcaagaaaga aacagatatt
    32941 atggatgtat ggtttgactc aggttcatca tggaatggtg ttttggtaaa tcgtccaaat
    33001 ctgacttatc cagctgacct ttaccttgaa ggttctgacc aataccgtgg ttggttcaac
    33061 tcatcactca ttacatctgt tgccaaccat ggcgtagcac cttacaaaca aatcttgtca
    33121 caaggtttta cccttgatgg taaaggtgag aagatgtcta aatcacttgg aaataccatt
    33181 gctccaagtg atgttgaaaa acaatttggt gcagaaatct tgcgtctctg ggtaacaagt
    33241 gttgactcaa gcaatgacgt gcgtatctct atggatattt tgagccaagt ttctgaaact
    33301 taccgtaaga ttcgtaacac tcttcgtttc ttgattgcca atacatctga ctttaaccca
    33361 gctcaagatg tagtcgctta cgatgaactt cgttcagttg ataagtacat gactattcgc
    33421 tttaaccagc ttgtcaagac cattcgtgat gcctatgcgg actttgaatt cttgacaatc
    33481 tacaaggcct tggtgaactt tatcaacgtt gacttgtcag ccttctacct tgattttgcc
    33541 aaagatgttg tttacattga aggtgccaaa tcattggaac gccgtcaaat gcagactgtt
    33601 ttctatgaca ttcttgtcaa aatcaccaaa ctcttgacac caatccttcc tcacactgcg
    33661 gaagaaatct ggtcatatct tgagtttgaa gctgaagact tcgttcaatt gtcagaattg
    33721 ccagaagctc aaacttttgc taatcaagaa gaagtcttgg atacatgggc agccttcatg
    33781 gacttccgtg gacaagctca aaaagccttg gaagaagctc gtaatgcaaa agttatcggg
    33841 aaatcgcttg aagcacactt gacagtttat ccaaatgaag ttgtgaaaac tctactcgaa
    33901 gcagtaaaca gcaatgtggc tcaacttttg atcgtgtcag acttgaccat cgcagaaggg
    33961 ccagctccag aagctgccct tagcttcgaa gatgtagcct tcacagttga acgcgctgca
    34021 ggtcaagtat gtgaccgttg ccgtcgtatc gacccaacaa cagcagaacg cagctaccag
    34081 gcagtcatct gtgaccactg tgcaagcatc gtagaagaaa actttgcgga agcagtcgca
    34141 gaaggatttg aagagaaata aggttgaaaa gtctaggcaa aattcaattt gagaagaaaa
    34201 gacaactaat tttatagtct attaaacgca ttgtatcacg tttttgaata cctgatatga
    34261 tgcgtttttt atttatttta aaaatttgcg aggtatgact ttttatactc aacaagaatc
    34321 aaagagaaac ttagcaagct aacagtagta agataaaata ggaatttgat att
//
LOCUS       DAVLBE010000019        33645 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.019, whole genome shotgun sequence.
ACCESSION   DAVLBE010000019 DAVLBE010000000
VERSION     DAVLBE010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33645)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33645)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33645
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.019"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            83..880
                     /locus_tag="VXB91_000951"
     CDS             83..880
                     /locus_tag="VXB91_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HEV0470427.1"
                     /translation="MVSSEFISKIEFACNKKESLYSQSKFKYAIRSMFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISW
                     RKTAEILLYCTLFNLIGALIAGWGFAHSAAYANLIHDSFISGVVEMKLGRSNELVLLE
                     AILANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGLLMGLPYAFLNKNEDTYVD"
     gene            1028..1150
                     /locus_tag="VXB91_000952"
     CDS             1028..1150
                     /locus_tag="VXB91_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine sulfhydrylase"
                     /protein_id="HEV0470428.1"
                     /translation="MTCDFKSETLQLHAGQVVAPATKSRAVPIYQTTFFVFDDT"
     gene            1172..2212
                     /locus_tag="VXB91_000953"
     CDS             1172..2212
                     /locus_tag="VXB91_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001231001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
                     /protein_id="HEV0470429.1"
                     /translation="MRKPGNIYTRITNPTTAALEGGVEALATASGMTAVTYTILALAH
                     AGDHVVAASTIYGGTFNLLKEPLPRYGITTTFVDVDNLEEVEAAIKDNTKLVLIETLG
                     NSLINIPDLEKLAEIAHKHQIPLVSDNTFAIPYLINVFSHGVDIAIHSATKFIGGHGT
                     TIGGIIVDSGRFDWMASGKFPQFVDEGSSCHNLSYTRDVGAVAFIIAVRVQLLRDTGA
                     ALSPFNAFLLLQRLETSSLRVERHVQNAETIVDFLVNHPKVEKVNYPKLADSPYHALA
                     EKYLPKDVGSIFTFHVKGGEEEARKVIDHLEIFSDLANAADAKSLVVHPATTTHGQLS
                     EKDLEAAGVTPN"
     gene            2383..3657
                     /locus_tag="VXB91_000954"
     CDS             2383..3657
                     /locus_tag="VXB91_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HEV0470430.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMKQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHEALLAKDKEV
                     QLLENQLATLRLEHENQLQKTLSDLEKERDQVKNQLLLQEKENELCLASVKQNYEAQL
                     KAASEQVEFYKDFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            3667..4545
                     /gene="truB"
                     /locus_tag="VXB91_000955"
     CDS             3667..4545
                     /gene="truB"
                     /locus_tag="VXB91_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HEV0470431.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMVEFMQDEGKIYEGEITLGYSTTTEDASGEVIAETPVLSPLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVIIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALSLEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            4786..5088
                     /locus_tag="VXB91_000956"
     CDS             4786..5088
                     /locus_tag="VXB91_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEV0470432.1"
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKYQS
                     VMANLSQGLSLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            5196..5834
                     /gene="udk"
                     /locus_tag="VXB91_000957"
     CDS             5196..5834
                     /gene="udk"
                     /locus_tag="VXB91_000957"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HEV0470433.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            5962..7302
                     /locus_tag="VXB91_000958"
     CDS             5962..7302
                     /locus_tag="VXB91_000958"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HEV0470434.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLTHLQNQEK
                     RMATAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLM
                     LDTSRIVARGYAIVKKEESIVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            7280..7492
                     /locus_tag="VXB91_000959"
     CDS             7280..7492
                     /locus_tag="VXB91_000959"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HEV0470435.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            7489..8364
                     /locus_tag="VXB91_000960"
     CDS             7489..8364
                     /locus_tag="VXB91_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HEV0470436.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLEALQVTIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDPYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQIIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQLPFE
                     TESIVSVVESLRING"
     gene            8357..9172
                     /locus_tag="VXB91_000961"
     CDS             8357..9172
                     /locus_tag="VXB91_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HEV0470437.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKIHQNVLESVTAMAVEA
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQIFAEIKEAVERAHSQFKNE"
     gene            9165..9596
                     /locus_tag="VXB91_000962"
     CDS             9165..9596
                     /locus_tag="VXB91_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEV0470438.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIDTFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            9603..11270
                     /gene="recN"
                     /locus_tag="VXB91_000963"
     CDS             9603..11270
                     /gene="recN"
                     /locus_tag="VXB91_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HEV0470439.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRAIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKERIEMLEFQMAEIEAANLQAGEDLALNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVHFSKGKFSRGGNEMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQHGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            11272..12000
                     /locus_tag="VXB91_000964"
     CDS             11272..12000
                     /locus_tag="VXB91_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HEV0470440.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQTQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYRRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEASDLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGFVAED"
     gene            12079..13902
                     /gene="lepA"
                     /locus_tag="VXB91_000965"
     CDS             12079..13902
                     /gene="lepA"
                     /locus_tag="VXB91_000965"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HEV0470441.1"
                     /translation="MNLEELKKRQGKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPESVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
     gene            complement(14151..14231)
                     /locus_tag="VXB91_000966"
                     /pseudo
     CDS             complement(14151..14231)
                     /locus_tag="VXB91_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            14405..14880
                     /locus_tag="VXB91_000967"
                     /pseudo
     CDS             14405..14880
                     /locus_tag="VXB91_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
     gene            14918..15220
                     /locus_tag="VXB91_000968"
     CDS             14918..15220
                     /locus_tag="VXB91_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0470442.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEARPILFRIPAMSVPVFDNIRLPAKQNMV"
     gene            15228..16029
                     /locus_tag="VXB91_000969"
                     /pseudo
     CDS             15228..16029
                     /locus_tag="VXB91_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            16078..16542
                     /locus_tag="VXB91_000970"
     CDS             16078..16542
                     /locus_tag="VXB91_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase"
                     /protein_id="HEV0470443.1"
                     /translation="MGGHPGFNCPLLDDEVYEDYYLEFEKEETCSVPRPFPETGMLDF
                     QDRSPWLEGQKEIDLSYDLFSKDAVTLDELQSRTIALRSLKHDRGLKVHFAEFPNLII
                     WSTLNKGPFITFEPWSGLSTFLEEGDHLEDKKNVCLLEANQVEELGFEIEVL"
     gene            16699..17124
                     /gene="lacA"
                     /locus_tag="VXB91_000971"
     CDS             16699..17124
                     /gene="lacA"
                     /locus_tag="VXB91_000971"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HEV0470444.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG"
     gene            17155..17670
                     /gene="lacB"
                     /locus_tag="VXB91_000972"
     CDS             17155..17670
                     /gene="lacB"
                     /locus_tag="VXB91_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HEV0470445.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPTEENKKLIAKIEHVESHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            17681..18610
                     /locus_tag="VXB91_000973"
     CDS             17681..18610
                     /locus_tag="VXB91_000973"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HEV0470446.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDNQVKKDFFSIQGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQDFLEHFKKLLESVEVVAISGSLPAGLPVDYYASLVELANQAGKPVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLDELKEVLQEPLFAGIEWI
                     IVSLGANGTFAKHGDTFYKVDIPRIQVVNPVGSGDSTVAGISSGLLHKESDAELLIKA
                     NVLGMLNAQEKMTGHVNMANYQVLYDQLIVKEV"
     gene            18612..19592
                     /gene="lacD"
                     /locus_tag="VXB91_000974"
     CDS             18612..19592
                     /gene="lacD"
                     /locus_tag="VXB91_000974"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEV0470447.1"
                     /translation="MALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGETAAREWLRTTGFENIDELNKVLQTTATSWKERV"
     gene            19826..20662
                     /locus_tag="VXB91_000975"
     CDS             19826..20662
                     /locus_tag="VXB91_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEV0470448.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIVIGKGIAFGKKKGDLIAENH
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALTQGRYKDSNLPDISAKYPVAFQIANEAFEIYCQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLTDYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            20698..21015
                     /locus_tag="VXB91_000976"
     CDS             20698..21015
                     /locus_tag="VXB91_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV0470449.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            21017..22711
                     /locus_tag="VXB91_000977"
     CDS             21017..22711
                     /locus_tag="VXB91_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEV0470450.1"
                     /translation="MDKLIIFIEKGKPFFEKLSRNIYLRAIKDGFISSMPAVLFSSIF
                     ILIAAVPNIFGFKWSDEQLAFILKPYNYSMGILALLVAGTTAKSLTDSVNTRSMEKTN
                     QINYMSTFLAAVVGLLILAADPIEGGFANGLLGTRGLLTAFLAAFITVNIYKVCIKNN
                     VTIRLPEEVPPNIAQVFKDVIPFALSVLSIYGLDLIVRNIFGTNVAESVGKILAPLFS
                     ATDGYIGLAIVFGAYAFFWFVGIHGPSVVEPLIVAISYANIEANVQLVQAGMHADKIL
                     NPVTQTFVVTMGGTGATLVVPFMFMWLCKSKRNRIVGRASVVPTFFGVNEPILFGAPI
                     VLNPIFFIPFVTAPIINVWIMKFFVDVLQMNSFSIILPWTTPAPIGIVMGTALAPLSF
                     VLAITLIIIDTLIYYPFVKVYDHQILEEERKGNSSSELKEKVAANFNTAKADAILEKA
                     GVDAAQNTITEETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLP
                     EFDLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQEQFD"
     gene            22926..24332
                     /gene="lacG"
                     /locus_tag="VXB91_000978"
     CDS             22926..24332
                     /gene="lacG"
                     /locus_tag="VXB91_000978"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEV0470451.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTGYGQVNAKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHACAVKLYKEKGYKGEIGVVHAL
                     PTKYPLDPENPADVRAAELEDIIHNKFILDATYLGRYSAETMEGVNHILSVNGGSLDL
                     REEDFTALEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGIGRR
                     VAPDYVSRTDWDWIIYPQGLYDQIMRVKKDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKQHLEILSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
     gene            24422..24634
                     /locus_tag="VXB91_000979"
     CDS             24422..24634
                     /locus_tag="VXB91_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HEV0470452.1"
                     /translation="MNFEKCSQIPCLTSEELKSLGKWYVSTGKEWICHSDDELEEFKN
                     LFLNFINPEEWDTISFDSDFMPFQQS"
     gene            complement(24913..25674)
                     /locus_tag="VXB91_000980"
     CDS             complement(24913..25674)
                     /locus_tag="VXB91_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV0470453.1"
                     /translation="MLKQEKLTKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSKFNKFDF
                     YTFYNISNLDTIVSDSKLSDSILFKLSKHIKVIKP"
     gene            complement(25962..26924)
                     /gene="nrdF"
                     /locus_tag="VXB91_000981"
     CDS             complement(25962..26924)
                     /gene="nrdF"
                     /locus_tag="VXB91_000981"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEV0470454.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAED
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLD"
     gene            complement(27112..29271)
                     /gene="nrdE"
                     /locus_tag="VXB91_000982"
     CDS             complement(27112..29271)
                     /gene="nrdE"
                     /locus_tag="VXB91_000982"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEV0470455.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWTELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            complement(29352..29570)
                     /gene="nrdH"
                     /locus_tag="VXB91_000983"
     CDS             complement(29352..29570)
                     /gene="nrdH"
                     /locus_tag="VXB91_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HEV0470456.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPEKLKQLA"
     gene            29921..30184
                     /locus_tag="VXB91_000984"
     CDS             29921..30184
                     /locus_tag="VXB91_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HEV0470457.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
     gene            30190..31923
                     /gene="ptsP"
                     /locus_tag="VXB91_000985"
     CDS             30190..31923
                     /gene="ptsP"
                     /locus_tag="VXB91_000985"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HEV0470458.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            32178..>33645
                     /locus_tag="VXB91_000986"
     CDS             32178..>33645
                     /locus_tag="VXB91_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEV0470459.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIFSEE
                     LLMKDPNYKLKDEDIVNEVKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTSTNDGAVAFARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAEAFLSGRGNLSNSRTYRRQNSDNTSRTNWLPSVSNPGTTNTNTSNNSN
                     TNSQASQSNDIDSLLKQLYKLPLSQRHVESDGLVFDPAQITSRTARGVAVPHGNHYHF
                     IPYEQMSELEKRIARIIPLRYRSNHWVPDSRPEQPSPQSTPEPSPSLQPAPNPQPAPS
                     NPIDEKLVKEAVRKVGDGYVFEENGVSRYIPAKDLSAETAAGIDSKLAKQESLSHKLG
                     AKKTDLPSSDREFYNKTYDLLARIHQDLLDNKGRQVDFE"
BASE COUNT        10390 a         6039 c         7374 g         9842 t
ORIGIN      
        1 acttttatga aatacagaaa acgcttccta aaacctaaag tttgtgatat aattatcaag
       61 aaaaaagatt taggagttta ttatggtttc ttcagaattt atctcaaaga ttgaatttgc
      121 ttgcaataag aaagaaagtc tttatagtca aagcaaattt aagtatgcga ttcgttcgat
      181 gttcgcaggt gcatttttaa ccttcagtac tgctgcaggt gcagttgggg ctgacttgat
      241 taataaaatt gcaccaggta gtggacgctt cctctttcca ttcgtttttg cttggggctt
      301 ggcctacatt gtttttttga atgccgagtt ggtcacttca aacatgatgt tcttgactgc
      361 tggtagtttc ttaaaaaaaa tctcttggag aaaaacagct gagattttac tatactgtac
      421 cttgttcaac cttatcggag ccttgatagc agggtggggc tttgctcatt cggcagccta
      481 tgcgaatctg atacacgata gtttcatctc aggtgttgtt gagatgaagt taggccgctc
      541 aaatgaattg gtcttgcttg aggcgatttt ggcaaatatt ttcgtaaata ttgcgattct
      601 gtcatttatt ttggtcaaag atggtggtgc caaactttgg cttgtgttgt cagctattta
      661 catgtttgta ttcttaacaa acgagcacat tgcggcgaac tttgcttctt tcgcgattgt
      721 gaaattcagt gttgctgcgg attcaattgc caacttcggt gttggaaata tgcttcgcca
      781 ctggggtgtg actttcatcg gaaactttat cggaggaggc ctcttgatgg gtcttccata
      841 tgccttcctc aataaaaacg aagatactta tgtagattaa gaaaatgagc acgattgagt
      901 cgtgcttttt tcattttcaa aataaggtaa tagctatttc ttatatcaaa atatagaaaa
      961 ctgatatttg taaactataa ctcaaggtgc tacaatatcc ttaataaaat gatatggagg
     1021 tcaccttatg acttgtgatt ttaaatctga aactctacaa ctacatgctg gtcaagttgt
     1081 ggctccagct actaagtctc gtgcagtgcc gatttatcaa acaacatttt ttgtttttga
     1141 tgacacgtag gaaggtgccg atctgtttgc cttgaggaaa ccagggaaca tttatactcg
     1201 tatcaccaat cctacaacag ctgcccttga aggtggtgtt gaagcgctag caacagcatc
     1261 aggtatgact gcagtgactt atacgatttt ggcgcttgcc catgctggtg accatgtagt
     1321 ggctgcttcg actatttacg gtggaacctt caatcttttg aaagaacccc ttcctcgtta
     1381 tggtatcaca acaacctttg tcgatgttga taatttggag gaagtagaag cagctatcaa
     1441 agacaatacc aagcttgtct tgattgaaac cttgggtaac tccttgatta atattccaga
     1501 cctggaaaaa ctggcagaga ttgctcataa acatcaaatc ccacttgtgt cagacaatac
     1561 ttttgcaata ccttatttga ttaacgtctt ctctcatggc gttgacattg ccattcactc
     1621 tgcgactaag tttatcggtg ggcatggtac aactattgga ggaataattg tcgatagtgg
     1681 tcgttttgac tggatggctt cagggaaatt ccctcaattt gttgacgagg gttcaagctg
     1741 ccacaatttg agctatactc gtgatgtggg tgcagtagcc tttattatag ctgttcgagt
     1801 tcaattgctt cgtgatacag gtgcagcctt gtcaccattc aatgctttcc tcttgctaca
     1861 aagacttgaa acctcttcac ttcgtgtgga acgccatgta caaaatgctg agacaattgt
     1921 tgattttctt gtcaaccatc ctaaggtaga aaaggtaaat tatccaaaac ttgcagatag
     1981 tccttatcat gccttggctg agaaatactt gccaaaagat gtcggttcaa tctttacctt
     2041 ccatgtcaaa ggtggcgagg aagaagcacg caaggtcatt gatcatttag aaatcttttc
     2101 tgaccttgca aacgcggcag atgctaaatc gcttgttgtc catccagcaa caaccactca
     2161 cggtcaattg tcagaaaaag acctagaagc agcaggtgtc acaccaaact aaattcgttt
     2221 gtcaatcggt cttgaaaatg tagaagattt gattgaagac ttgcgcttgg ccttggaaaa
     2281 aatttaaagt aaaagaagat aaacagtggg cttcgactca ctgtttttga ttttccctca
     2341 ggcatgatat aatggttaaa gaagtctaga aagaggaacg atatgaacga aatcaaatgt
     2401 cccaactgtg gggaagtctt tacagtaaat gagagtcagt atgccgaact cttgtcccaa
     2461 gtgagaacgg cagagtttga taaggaacta cacgatagga tgaagcagga actggccttg
     2521 gctgagcaaa aggccatgaa tgagcaacag actaaactgg ctcagaagga tcaagaaatt
     2581 gcgcaattac agagtcagat ccaaaacttt gatacagaaa aagaattggc caagaaagag
     2641 gttgaacaga caagccatga ggctctcttg gctaaggaca aggaagtaca gctcttagaa
     2701 aatcagttgg ctaccttgcg tttggagcat gaaaatcaac tgcaaaagac cctttctgac
     2761 ctagaaaaag aacgggatca ggttaaaaac caactacttt tgcaggaaaa ggaaaatgaa
     2821 ttatgtttgg cttctgttaa gcaaaactac gaagcccagc tcaaggcagc tagtgaacaa
     2881 gtcgagtttt ataaggattt taaggctcaa caatctacaa aagcgattgg ggaaagccta
     2941 gaacagtatg cagagagtga gtttaacaag gttcgtagtt tcgcctttcc aaatgcttac
     3001 tttgagaagg ataacaaggt ctcttcgcgt gggtctaaag gggactttat cttccgtgag
     3061 tgtgatgaaa atggagttga aatcatttct atcatgtttg agatgaaaaa cgaagcagac
     3121 ggaacagaga agaagcacaa gaatgcagat ttttacaagg aattggacaa ggaccgtcgg
     3181 gagaagaact gtgagtatgc cgttttggtg accatgcttg aggccgataa tgactacttt
     3241 aacacaggga ttgttgacgt cagccacgag tatgaaaaaa tgtatgttgt tcgtcctcaa
     3301 ttctttatcc agttgattgg tctcttacgt aatgcggcgc taaattccct aaaatacaag
     3361 caggagttgg ccttggttcg cgagcaaaat attgacatta cgcattttga ggaagacttg
     3421 gatgccttta agctagcttt tgctaagaac tataattcag cttcgactaa ctttggaaaa
     3481 gctattgatg aaatcgacaa ggccatcaaa cgcatggaag aggttaagaa attcctgact
     3541 acatctgaaa accaactccg tctagctaac aacaaattgg aagatgtctc tgttaaaaaa
     3601 ttgacccgga aaaatccaac aatgaaagcg aagttcgaag cactgaaggg ggagtagaaa
     3661 gcaaaaatga acggtattat caacttaaaa aaagaagcag gaatgacctc gcatgatgcg
     3721 gtttttaaac tgcgtaagat tttgggaacc aagaaaattg gtcatggtgg aaccttggat
     3781 ccggatgtgg tgggtgtttt gccgattgcg gttggcaagg cgacacgcat ggtcgagttt
     3841 atgcaggacg agggtaagat ctatgagggg gaaattactc tgggttattc cacgacgact
     3901 gaggatgcta gtggggaagt gatcgcagaa acccctgttt tgtctccctt ggatgaaaag
     3961 cttgttgatg aagcgattgc tagcttgact gggcctatta cccagattcc ccctatgtat
     4021 tcggcagtta aggttaatgg tcgcaagctc tatgagtatg cgcgtgctgg tcaggaagtg
     4081 gagcgtccag aacgtcaggt gatcatttat caatttgagc gaacaagtcc gatttcttat
     4141 gatggccaac ttgcccgatt cacttttcgt gtaaaatgca gtaaagggac ttacatccgt
     4201 actttgtcag ttgatttggg tgaaaagctt ggttatgcgg ctcatatgtc ccatttgact
     4261 cgtactagtg ctgctggctt acaattagaa gacgctcttt ccttggagga aattgctgaa
     4321 aaagtagagg ctgggcaatt agattttctc catcctttag agattgggac aggtgacctt
     4381 gtcaaagttt tcctaactcc agaagaggct acagaagttc gctttggtcg ttttattgag
     4441 ctagaccaaa cggacaaaga actggctgcc tttgaagatg ataaattgtt agccattcta
     4501 gaaaaacggg gcaatctcta taagccaagg aaggttttta gctagatcgt ttaggaataa
     4561 aaatcgggtg atagataaca attgcttgat aaaaccccat actaatagta gaatggtttt
     4621 gggaattata atattccaat tgttgcgagt tgtaggtact caaataatct atatagaaat
     4681 ttagaggtgt gaaatgaagc aatttaaaat tctttcagat aaatatttag agtccattac
     4741 aggttctggt gggaacttag gcccaggatt tggtgtgata attccatgat gcgaaatgag
     4801 tttcgagaaa gggtggagca acttcttcaa caaaaagaaa taaatgaaaa tagtgagttg
     4861 agtcacctgt ttcgtcttgc tatacaaaat ttagacagaa atgaaaaata ccaatcggtc
     4921 atggccaatt tgagtcaagg gttgtcactt tacctcatga cgcatcatta ccaggcacct
     4981 aagtctgtca ttgattttgg tttatggatt gccaaagctc ctagccagga aagagggaga
     5041 ctggctttct tgcagatgct tgctcaaacc ctacagggct ttcgttaaaa ctgtcgaaca
     5101 tcagagggaa gactctggtg ttttttgctg atgagactat aaattttgta aaaaatgtga
     5161 tagaatagac gacggataaa ataacggagg atagcatgca aaatagacca atcattattg
     5221 gagtgacagg tggttctggt ggtggtaaaa ccagtgtttc aagagccatt ttatcgcatt
     5281 ttcctgatga aaagatttcc atgattgagc atgattcata ctacaaggat cagtctcatt
     5341 tgacctttga agagcgtgtc aaaaccaact atgaccatcc ttttgccttt gatacagact
     5401 tgatgatcga gcagattaag gaattgttgg cagggcgtcc ggtggacatc ccgacctacg
     5461 actatacaga gcatacacgg agtagcaaga cctatcgtca ggagcctcaa gatgtcttta
     5521 tcgttgaggg cattttggtc ttggaggaca agcgtctgcg cgatttgatg gatatcaaga
     5581 tttttgtgga tacggatgac gatgtgcgta ttattcgtcg tatcaagcgt gatatggagg
     5641 aacgtggccg tagccttgat agcgttatta accagtactt aggtgtggtc aaaccaatgt
     5701 accaccagtt tatcgagtca actaagcgtt atgctgatat cgtcattcct gaaggggtta
     5761 gcaataccgt ggctatcgac ctgttgacga ccaagattgc aaagattttg gaagaagctc
     5821 gaaacagcaa ataatcacat gtggaggcct tgcctccttt ttctattttt ccctcataat
     5881 ggtacataaa tggagatttt taggcatatt tttggtataa taatacccat aaaagagcaa
     5941 gtaaatgaat agtaggtgga gatggaaaag tatttatcgg taacaacttt gaccaaatat
     6001 ctgaaaatga aattcgataa agacccatac ttggaacggg tctatttaac tggtcaagtt
     6061 tccaactttc gtaaacgacc tactcaccaa tatttctccc taaaggatga ccatgcagtt
     6121 attcaagcga ccatctggtc tgggatttat cagaaattag ggtttgacct ggaagaagga
     6181 atgaagatca atgtgattgg gcgtgtacag gtctatgaac caagtggtag ctactccatc
     6241 atcattgaaa aagctgagcc tgatggggtt ggggcgcttg cgattcagtt tgaacaactt
     6301 aagaaaaaat tgacagaaga aggcctgttt caagaacgct tcaagcaagc tctaccccaa
     6361 ttttctaaga gaattggggt agtaaccagc cgtagtggag ccgttattcg agatattatc
     6421 acgaccgtca gcaggcgatt cccaggtgtt gacatccttc tttatcctac caaggttcaa
     6481 ggtgaagggg ctgcggagga aattgctaga aatattgcgc gtgctaatca acgggacgat
     6541 ttggatttgc tcattattgg tcgtggaggt ggttctattg aggatctctg ggcctttaac
     6601 gaagaaattg tggtacgagc tatttttgaa tctcgtttgc cagttatctc tagtgtgggg
     6661 catgagacgg atgtgacctt ggcagatttt gtggcagatc gacgcgctgc aacgccaaca
     6721 gcggcggctg aactggcaac acctgtgacc aagttggatg tattaactca tttgcaaaat
     6781 caggaaaaac ggatggcaac ggcagtccga aatgttctat ctaagaaaca agaggctttg
     6841 aaaaaatgca gtcagtctgt tatctttaga caacctgagc gcttgtatga cggttatttg
     6901 caacgcttgg accaactgca actgcgtttg aaacaaagtt tgcgaactcg gatttctgat
     6961 aacaaacaat tagttcaagc aagaactcat caattagtac aattatcacc tgttaccaaa
     7021 atccaacgct atcaagaccg tttaggacag ttggacaagc tcttaggtag ccaaatggcg
     7081 ttagtttatg acgccaaggt tgctgaggcc aagcgacttt cggaagcttt gctcatgttg
     7141 gatactagcc gaatcgtggc gcgtggttat gctattgtca aaaaagaaga gtccattgta
     7201 gattcggttg agagtttgaa gaaaaaagac caagtaacgc ttttgatgcg agatggtcaa
     7261 gtagaattag aggttaaaga tgtcaaaaca aaagaaattt gaggaaaatc tagcagaact
     7321 ggaaaccatt gtccaaagtt tggaaaatgg tgaaattgct ctggaagatg cgattactgc
     7381 ctttcaaaag ggcatggtct tgtcaaaaga gctccaagct acgctggaca aggctgaaaa
     7441 gaccttggtc aaggtcatgc aagaagacgg aacagaaagt gattttgaat gaaaaagcaa
     7501 gaaaaattag ctcttgtcga gtcggctttg gaagattttt atggagacca gcagtttgcc
     7561 tctagtttac gggagtctgt tctctattct attcatgctg gtggcaagcg tattcggcct
     7621 tttctcttgt tagaagttct ggaagccttg caggttacca tcaaacctgc tcacgcgcag
     7681 gtagctactg ccttggagat gattcataca gggagcttga ttcacgatga ccttcctgct
     7741 atggatgatg acgattatcg aagagggcgg ttaaccaatc acaagaaatt cggtgaagct
     7801 atggccattt tggctggaga tgccttattc ttagacccat atgccttgat tgcgcaggca
     7861 gatttgccaa gtcagattaa ggtggacttg attgccaact tatcccttgc ttcaggtagt
     7921 ctgggtatgg tggcagggca agttttggat atggagggcg aacaccagca cttgtctttg
     7981 gaagaacttc agattattca tgccaataag actgggaagt tactagccta tcccttccaa
     8041 gcggcagcta ttatagctga attgtcacct gaaatgcagg tgaagctgaa aactgtgggt
     8101 gaattgattg gacttgcttt tcaagtcaga gatgatgtac tggatgtgac agctagtttt
     8161 gaggaaatcg gcaagacacc tcaaaaggat ctgcaggcag aaaaatcaac ctatcctgcc
     8221 ctgttgggct tggaagagtc cattgccttt tgtaaccaaa ccctggatca agctaatgaa
     8281 aaattagaag aaattgccca gcagcttccc tttgaaacag aatcgattgt aagtgtagta
     8341 gaaagtttga gaatcaatgg ctaaggaaag agtggatgta ctagcttata aacaggggtt
     8401 gtttgaaacg agagagcagg ccaagcgagg tgtaatggct ggcctagtcg tagcagtcct
     8461 taatggagaa cggtttgaca agccaggaga gaaaattcca gatgacaccg aattaaaact
     8521 caagggagag aaactcaagt atgtcagccg tggtggtttg aaactggaaa aggccttgca
     8581 ggtctttgat ttgtcggtgg atggcgcgac tacgattgat atcggggcct ctactggagg
     8641 ttttaccgat gtcatgctac agaatagtgc caagttggtc tttgcagtcg atgttggtac
     8701 caatcagttg gcttggaaat tacgccaaga cccacgagtt gttagcatgg agcagttcaa
     8761 tttccgctat gctgaaaaga ctgatttcga gcaggagccg agctttgcca gtattgatgt
     8821 gagtttcatt tcccttagtc tgattttgcc agccttgcat cgtgtcttgg ctgatcaagg
     8881 tcaggtggta gcacttgtca aacctcagtt tgaggcagga cgtgagcaga ttgggaaaaa
     8941 tggaattatt cgagatgcta agattcatca gaatgtcctt gaatctgtaa cagctatggc
     9001 agtagaggca ggtttttcag tccttggctt ggacttttct cccatccaag gtggacatgg
     9061 aaatattgaa tttttagcgt atttgaaaaa agaaaagtca gcaagcaatc agatttttgc
     9121 tgagattaaa gaagcagtag agagggcgca tagtcaattt aaaaatgaat aaaaaagaga
     9181 gacttgaaaa aattagaaga ttggtgacag attatcaaat cggcacgcaa gaagaaattg
     9241 tagaacattt gaaagaagca ggtatcactg ccactcaggc gacggtatcc cgagatatca
     9301 aagagttagg tattgtcaaa attcctttga gagacaacac ctatgtctac gaattaccaa
     9361 aatcaatcgt aaaaagtctg caactggctg aagacaatat cgaatcggct gaattgatgg
     9421 ataagatgat caatctccaa gttattccag gaaatacggc ttttgtaaaa gctcagttaa
     9481 tcgatacttt tgcagacaag atttttagtt gtttgactga tgatagctcg attttagtca
     9541 ttgccagaag tggaagtcta gcagaggaaa tctttgaaca agtaaaaaat tggtaggtct
     9601 atatgttact tgaaatttcg ataaaaaact ttgccattat tgaggctatt tccctcaatt
     9661 ttgaaaaggg gatgactgtc ctgactggtg aaacgggtgc agggaagtcg attatcattg
     9721 atgccatgaa tatgatgttg ggagctcgtg cgacgacaga tgttattcgt catggtgcac
     9781 caaaggcaga gattgagggg cttttctcag ttgagaatag tcgtctttta caggaaattt
     9841 ttgatgagca aggtttagaa ttaggtgatg aaattatcat ccgtcgggaa atcttgcaaa
     9901 atggtcgtag tatcagccgt gtaaatggtc agatggttaa tctgtctgtt ttgcgagcta
     9961 ttgggcaaca tcttgtagat attcatggtc agcatgacca tgaggagtta atgcgtcccc
    10021 aactgcatat ccagatgttg gatgaatttg gtgatgccgc tttttgggac ttgaaagaaa
    10081 cctatcaaac gagttttgat gcctatcgga aaatgcgcaa gcaggttctg gaagtcaaga
    10141 aaaaccaaca ggaacacaag gaacgtatcg aaatgttgga atttcaaatg gcagagattg
    10201 aggcagcaaa cttgcaggct ggagaagact tggctctcaa tcaagagcga gataaactcc
    10261 tcaaccacaa aaatattgcg gatacactga ccaatgccta cagtatgttg gacaatgaag
    10321 atttttcaag tctggccaat gttcgttcag ctatgaatga catggaaagt gtcgaagagt
    10381 atgatcctga ataccgtgaa atttcaagct ctctgtctga gacctactat gttttagaag
    10441 acattagcaa acgtttggaa gctatcattg aggaccttga ttttgatggc aatcgcctga
    10501 tgcaggttga gaatcgtttg gacctccttc atactattac tcgtaagtat ggtgggactg
    10561 ttgatgatgt tttgctttat tttgccaaga ttacggaaga atacaatctc ttgacaggca
    10621 ataatctttc gtctgaggac atggaagcag agcttaagaa gttggaagtc aatcttgtca
    10681 atttggcagg tcaacttgct tctgctcgtc ataatttggc tcagcaactc gaagctgaga
    10741 ttaaacaaga actgcaagat ctttatatgg aaaaagccca gtttcaggtt cattttagta
    10801 agggaaaatt cagtcgtggg ggaaatgaaa tggttgagtt ttatatttca accaaccctg
    10861 gagaagactt taaacccttg gttaaggttg cttctggagg ggaattatct cgtctcatgt
    10921 tagccattaa gtctgccttt tcacgtaaag aaggcaagac tagcattgtc tttgatgagg
    10981 tggatacggg agtttcaggt cgtgttgctc aagctattgc tcagaaaatt cataaaattg
    11041 gtcagcatgg tcaggttttg gctatctccc atttgccaca agtaattgcg attgcagatt
    11101 atcaattctt tattgagaag attagtaatg accattcaac ggtttcgact gttcgtctct
    11161 tgacagtcga agagcgagtg gaggaagttg ccaagatgtt ggcaggtgat gatgtgacag
    11221 aagcagccct gacgcaagcc agagaattgt tgagaaacag ggagaaataa gatgacagat
    11281 tattatgtaa ttggagatgt tcacggaaaa gctgggatgc tggaagacct tcttaaaacc
    11341 tgggatggtc agacccagtt gctctttcta ggtgatttga ttgacagagg tgaggatagt
    11401 caccgtgttc ttgaaatggt caaggacttg gtggacaatc aaggggctat ctgtttgtct
    11461 ggaaaccacg agtatatgtt tttgacttgg ctagatgacc cagaagaaag ttatgaccat
    11521 tatcgtcgca atggtggaga tacaaccatt aactctatcc taggtcgtcc cttggatgca
    11581 ccagttgatg gagtagaaga tgccaagcgg gttgccgctg aagcgtcaga cttggtcgaa
    11641 ttcattcgtc aaatgccatt tgtagtagag acagacaagt atatatttgt tcacgcaggt
    11701 attgatttga ctttggacga ctggcatgaa acaacagatt ataaaaaagt atggcttaga
    11761 aaaccattcc acggagctga aaatcatact ggaaaaacca ttgtcttcgg tcatacaccg
    11821 gtctatggtt tgttacagca agaacgcggt acatctgagc tttggactac agaagatggc
    11881 aagattggaa tggatggagg agctgtttat ggtggtgtcc ttcacgggat tgtctttaca
    11941 gaccaaggaa tgacagaaca ccactttatc gaaaatgacg gctttgtcgc tgaagattag
    12001 tactcctagc agggtatggt cttgtcaaaa tatcaaaaac aatttataat aaatagatac
    12061 cctgaaagga agagaatcat gaacttagaa gaattgaaaa aacgacaggg gaagatccgt
    12121 aacttctcta ttatcgccca tattgaccac gggaaatcaa ctctagcaga ccgcattttg
    12181 gaaaaaacag agacggtttc aagtcgtgaa atgcaggccc agcttttgga tagcatggat
    12241 ctagagcggg aacgtggaat tactattaag ttgaatgcca tcgagttgaa ttacactgca
    12301 aaagatgggg aaacttatat tttccacttg attgacacac cagggcacgt tgactttacc
    12361 tatgaagttt cacgttcgct agctgcctgt gagggtgcta ttttggtggt cgatgcggct
    12421 caaggaattg aggctcaaac tcttgccaac gtttatctgg ctttggataa tgatttggaa
    12481 atcatgccta tcattaataa aattgacctg ccggctgcag atccggagag cgtgcgtaca
    12541 gagattgaag atgtgattgg tttggatgcc agtgaagcag ttttggcttc tgccaaggct
    12601 ggtattggga ttgaagaaat cctcgagcaa attgtagaaa aagtaccagc accaacgggt
    12661 gatgtgacgg cgccacttaa ggccttgatt ttcgactctg tttacgatgc ttaccgtggg
    12721 gttatcctcc aagtgcgtgt catggacgga gtggtcaaac ctggtgataa gattcagctc
    12781 atgagcaata gtaagacctt tgatgtggcc gaagtcggta tttttacacc aaaagcggtt
    12841 ggtcgtgatt tccttgcgac tggtgatgtt ggttacattg cggcgtctat caagacggtt
    12901 caggatactc gtgtgggtga taccgttacc ttggcaacca atcctgcggc agaaccatta
    12961 catggttata agcagatgaa tcctatggtc tttgcgggtc tctacccaat cgaatcaaac
    13021 aagtacaatg acctgcgtga agcgcttgaa aaattgcaac tgaatgatgc tagtcttcag
    13081 tttgaaccag aaacatctca ggcacttgga tttggtttcc gttgtggatt tcttggactt
    13141 ctccatatgg atgttatcca ggaacgttta gagcgtgagt tcaatattga tctcatcatg
    13201 acagctccgt ctgttattta caaagttaat ttgaccgacg gtgagtctat ggatgtgtct
    13261 aacccatctg agtttccaga cccaactaag attgcgacca ttgaagagcc ttatgtcaag
    13321 gcgcaaatca tggtaccaca ggagttcgtc ggagcagtaa tggagctagc tcagcgtaag
    13381 cgtggggact ttgtgactat ggactatatt gatgataacc gtgtcaatgt tatctatcaa
    13441 attcctcttg ctgaaatcgt ctttgacttc tttgataaac ttaagtcttc gacacgtggt
    13501 tatgcaagtt ttgactacga attgtcagaa tatcgcccat ctaagctagt gaaaatggat
    13561 atccttctca acggagacaa ggtggatgcc ctcagcttta tcgttcataa ggactttgct
    13621 tatgaacgtg ggaaactcat cgttgataag ctcaagaaaa tcatccctcg ccaacaattt
    13681 gaggttccaa tccaagcggc tattggacac aagattgtcg ctcgtactga tatcaaggcc
    13741 cttcgtaaga acgtacttgc taaatgttat ggtggtgacg tttctcgtaa gcgtaaactc
    13801 cttgaaaaac aaaaagctgg taagaaacgc atgaaatcca tcggatcagt tgaagttccg
    13861 caagaagcct tcctcagcgt cttgagtatg gatgaagaat aagttatcag aaatgccttt
    13921 ccttgttcac aggaaattta tataagaatc aatagtaaag caggcttaga tggtctgctt
    13981 ttttagtttt tatactcttc gaaaatctct tcaaaccacg tcagcgtcgc cttaccgtat
    14041 gtatggttac tgacttcgtc agtttcatct acaatctcaa aaccatgttt tgagctgact
    14101 tcgtcagttt catctacaac ctcaaaacca tgttttgagc tgacttcgtc agtttcatct
    14161 acaacctcaa aactgtgttt tgagtaacct gcggctagct tcctagtttg ctctttgatt
    14221 ttcattgagt attagaacag aaaaatgctt ggagtatttg tttgtgtgtt tatttttata
    14281 taacaaacta taaacacaac aaaaatataa aaaaagagac aaaaaagaac agaaagtaat
    14341 taacaacgat ttcatatagt gttatactta tagcataaag ttaatggaaa gaagggaaaa
    14401 ccttatggta ttagattatt tctttgacaa aaaccttgtg ttttgcttag aagcggataa
    14461 tcaagaataa ctctttgatc aggtagcaag cttgttggag gaacgagaaa ttgtaactcc
    14521 aacttatcgt gaagctttga tcacgcgtga aaagtcattt ccaactggtt tagatatgga
    14581 atttctagga aaggacttgc aaatgtaatg attcctcaca cagatattgt tcataatcta
    14641 gctgagaaag tggtggttgt tcgattagag aaaccggtga ctttccataa tatgattgcg
    14701 ccaggtaagg aagtagaagt atccttgctc ttctttatca tcaataattc aagttcaagt
    14761 caaacgaaca ttcttgctca gttgatggac tttttcacag gaaatggaca tcttgaagac
    14821 ctatcaaaaa tttccgaacc agaaaaactt tatgcttata tagatgaagc aatcgcttaa
    14881 tcttgtctat taaaaaataa aatcggagga agtctatatg attaaaattc ttgctgcctg
    14941 cggtgcaggt gttaactcaa gtcaccaaat taaaagtgct ctagaagaag aactttcaaa
    15001 ccgtggttac gatgttcact gtgatgcagt tatggtgaaa gatgtaaacg aagaccttat
    15061 gaaaggttac gatatcttta caccaatcgc tgcaacagac cttggttttg aaccaggtat
    15121 cccagttatc gaagctaggc caatcttatt ccgtatccca gcaatgagcg ttccagtatt
    15181 tgacaatatt agacttcctg cgaaacaaaa tatggtatag tagttctatg aatgatgaag
    15241 caagtaaaca actaactgat gcacgattta agcgtcttgt tggtgttcag cgtaccactt
    15301 ttgaagagat gttagctgta ttaaaaacag cttatcaact taaacacgca aaaggtggac
    15361 gaaaacctaa attaagccta gaagaccttc ttatggccac tcttcaatag tgcgagaata
    15421 tcgaacttat gaacaaattg cggctgattt tggtattcac gaaagcaact ttatccgtcg
    15481 gagccaatgg gttgaagtaa ctcttgttca aagtggtgtt acggtttcaa gaactcctct
    15541 cagctctgag gacacggtaa tgattgatgc gacggaagta caaatcaatc gccctaaaaa
    15601 agaattagcg aatgattctg gtaaaaagaa atgccacgct atgaaggctc aagcgattgt
    15661 cacaagtcaa gggagattgt ttctttggat atcactgtga actattgtca tgatatgaag
    15721 ttgttcaaaa tgagtcgcag aaatatcgga caagctggta aaatcttggc tgacagtggt
    15781 tatcaagggc tcatgaagat atatcctcaa gtacaaactc cacgtaaatc cagcaaactc
    15841 aagccgctaa cagttgaaga taaaacctat aaccatgcgc tatctaagga gagaagcaag
    15901 gttgagaaca tctttgccaa agtaaaaacg tttaaaatga tttcaacaac ctatcgaaat
    15961 catcgtaaac gcttcggatt acgaatgaat ttgattgctg gcattatcaa tcatgaacta
    16021 ggattctagt tttgcaggaa gtctaataaa gaaactagca aggtcaggcc ttactttatt
    16081 ggtggacatc caggatttaa ttgtcctcta cttgatgatg aagtctatga agattattat
    16141 ctagagtttg agaaagaaga gacttgctct gttccacgtc ctttcccaga aacaggtatg
    16201 ttggatttcc aagatagaag tccatggcta gagggacaaa aagaaataga tcttagttat
    16261 gatcttttca gcaaagatgc agtgactttg gatgaattgc aatctcgaac aattgccctt
    16321 cgttctctta aacatgatag gggattgaaa gtgcattttg cagaatttcc aaacctcatc
    16381 atctggtcaa ctttgaacaa gggacctttc attacctttg aaccatggtc tggcttgtca
    16441 acattccttg aagaaggaga tcatttagaa gataagaaga atgtttgtct cttagaagcc
    16501 aatcaggttg aagaattagg gtttgagata gaagttttat aaaaaagtaa aaaataaata
    16561 acaaaaacaa acacaaactg ttgacttctt caaacaatag tagtatatta tgtttgtgag
    16621 gactaattga ctgtttttta aagacagcca atacactgct ggaatccagc atagaaaaaa
    16681 taaaaaggag tatacaatat gtctattgtt atcggtgcag atgctgcagg tttgagattg
    16741 aaagaagttg tgaaagactt cttagaaaaa gaaaacttcc accttgtgga tgttacagct
    16801 gaaggtcaag actttgttga tgtgactctc gctgttgctg cagaagtaaa caaagaagaa
    16861 caaaaccttg gtatcgtgat tgatgcttat ggagctggtc catttatggt tgcaactaag
    16921 atcaaaggaa tggttgctgc agaagtttct gatgaacgtt cagcttatat gactcgtggc
    16981 cacaacaact cacgtatgat cactatgggt gcacaacttg ttggtgatga attggctaaa
    17041 aacatcgcta aaggatttgt taatggtaaa tacgacggtg gtcgtcacca aatccgggtt
    17101 gacatgttga acaaaatggg ctaattagat tatagtaaga aaggtaagtt aaaaatgaga
    17161 attgcaattg gatgtgacca catcgtaaca gatgaaaaaa tggcggtttc agaatttttg
    17221 aaatcaaaag gatatgaagt cattgacttt ggtacatatg accatacacg tactcactac
    17281 ccaatctttg gtaaaaaagt aggggaagct gtaactagcg gtcaagctga tcttggagta
    17341 tgtatctgtg gtactggtgt tggtatcaac aacgctgtaa ataaagttcc aggtgttcgt
    17401 tctgccttgg ttcgtgatat gacaacagcc ctttatgcta aagaacaatt gaacgctaac
    17461 gttattggtt ttggtggtaa aattactggt gaattgctta tgtgtgatat catcgaagct
    17521 ttcatccatg ctgaatacaa accaactgaa gaaaacaaaa aattgattgc gaaaattgaa
    17581 catgttgaaa gtcacaatgc tcaacaaaca gacgcaaact tcttcactga attccttgaa
    17641 aaatgggatc gcggagaata ccacgactaa gaggtaacct atgattttaa cagttacaat
    17701 gaacccatcc attgatattt cctatccctt ggatgagttg aagattgata ctgtcaatcg
    17761 tgtggtggat gtaaccaaaa cggctggtgg taagggactc aatgttaccc gagtactttc
    17821 agaatttggc gattctgttc ttgctactgg tttagtgggt ggcaaacttg gtgagttttt
    17881 ggttgaacat atcgataatc aagtaaagaa agatttcttc tcaattcagg gagaaactcg
    17941 taactgtatc gctattctcc acggagacaa ccaaacagaa gttcttgaaa aaggtcctga
    18001 agtattggaa caggaaggtc aagacttttt ggaacatttc aaaaaactct tggagtcagt
    18061 tgaagtagtg gccatctcag gtagtctgcc agctggcctt ccagttgatt actatgcgag
    18121 cttggtagaa cttgctaatc aagctggcaa gcctgtagtc ttggactgct caggtgcagc
    18181 acttcaggct gttcttgaat caccccataa accaacagtc atcaaaccaa ataatgaaga
    18241 attgtctcag cttcttggaa gagaagtttc tgaggatttg gatgaattaa aagaagtact
    18301 tcaagaacct ttgtttgcag ggattgaatg gattatcgtt tcacttggtg ccaacggtac
    18361 ttttgccaaa catggtgaca ctttctacaa ggtagatatt cctagaattc aggtggtaaa
    18421 tcctgttgga tctggagact ctactgtggc aggaatttct tcaggacttc ttcacaaaga
    18481 atcggatgca gaattactca tcaaggcaaa tgtccttggt atgctcaatg ctcaagaaaa
    18541 aatgactggt catgtcaaca tggccaacta tcaagttcta tatgatcaat taatagtaaa
    18601 agaggtataa aatggcttta acagaacaaa aacgtgtacg cttagaaaaa ctttctgatg
    18661 aaaatggtat catctcagct cttgcatttg accaacgtgg tgctttgaaa cgcctcatgg
    18721 ctcaacacca aacagaagaa ccaactgtgg cccaaatgga agaacttaaa gtcttggtag
    18781 cagatgaatt gactaaatac gcttcatcta tgcttcttga ccctgagtat ggacttccag
    18841 caactaaagc tcttgatgaa aaagctggtc ttctccttgc ttatgaaaaa acaggttatg
    18901 acacaacaag cacaaaacgc ttgccagact gcttggatgt ctggtctgca aaacgtatta
    18961 aagaagaagg tgcagatgca gttaaattct tgctttacta tgatgtagat agctcagacg
    19021 aactcaatca agaaaaacaa gcctacatcg aacgcatcgg ttctgagtgt gtggctgaag
    19081 atatcccatt cttccttgaa attcttgctt acgatgaaaa aattgcggat gcaggttctg
    19141 tagaatacgc gaaagtaaaa ccacacaaag ttatcggcgc tatgaaagtc ttttcagacc
    19201 cacgctttaa cattgatgtc ttgaaagttg aagttcctgt taacattaaa tatgttgaag
    19261 gcttcgctga aggtgaagta gtttatacac gtgaagaagc agcagccttc ttcaaagcgc
    19321 aagatgaagc aacgaacttg ccatacatct acttgagtgc tggtgtatca gctaaactct
    19381 tccaagatac tcttgtattt gctcatgaat caggtgcaaa ctttaacgga gttctttgtg
    19441 gccgtgcaac atgggctgga tcagttgaag catacatcaa agatggtgaa acagcagctc
    19501 gcgaatggct tcgcacaact ggatttgaaa acattgatga gctcaacaaa gttcttcaaa
    19561 caacagcaac ttcatggaaa gaacgtgtgt aagaaagtcc tcctagttta ggaacatgaa
    19621 tctaaaaaaa tttaaaaaaa gttgtatgta aaggtttaca aaataactta cttgtgctat
    19681 acttaaatca caagttaata caaggtgagt gttactaagt aatattaggc atgatcacag
    19741 gtgaattaga aatcagctga ttttctagtt catttgtggt cattttttgt actcatatac
    19801 ctttaagata taaaaggagg ttgacatgta tcgaattcta aatccaatga atcacaatgt
    19861 ctcgcttgtc agaaatgata agggagaaga ggtgattgta attggtaagg ggattgcatt
    19921 cggaaagaag aagggggatt tgattgctga aaatcatgtt gagaaaatct ttcggatgaa
    19981 gaccgaagag tccagagaaa actttatggc tcttctcaaa gatgttccgc ttgattttat
    20041 cacagtgacc tatgaaatca ttgataagct atcaaagaaa tatcattatc cgattcaaga
    20101 gtatctctat gtaaccttga cagatcatat ttactgttct tatcaagctc taactcaagg
    20161 aaggtacaag gatagtaatc tgccagatat ttctgctaag tatcctgtcg cttttcaaat
    20221 cgcaaatgaa gcttttgaaa tttactgtca gaagctagca gatcattttc ctgaggacga
    20281 aattattcgg attgcttatc atttcattaa tgctgaaggt gaaaatgaag tggaacttgt
    20341 ggagtcgatt gataagagga aagaaattct caggaatgtt gaagaagttt taacggacta
    20401 tgcaattcaa cgaactaaaa agaataacca tttctatgat cgctttatga tccatttgaa
    20461 ttatttcttg gattatttag acagatctag agatgataac caatcacttc tggatatgga
    20521 agatcatatt aaacaatcct atccaaaagc cttcgagatt ggttccaaga tctatgatgt
    20581 gattacgcaa catacgggtc ttgatttgta taaaagtgaa cgagtttatc tagttctaca
    20641 tatccaacgt ttattgtcat aaaaatttat ttaaaactat ataaggagaa ttctatcatg
    20701 aatagagaag aagtaacatt gttaggtttt gaaatcgtag cctatgctgg cgatgctcgt
    20761 tcaaaactat tggaagcctt gaaggctgct gaagctggtg attttgaaaa agcggacgct
    20821 ctggtagagg aagctggtag ctgtattgca gaggctcacc acgcgcaaac aagtctattg
    20881 actaaggaag cttctggtga ggacttagcg tatagtgtga ccatgatgca tggtcaagat
    20941 cacttgatga caactatctt gttaaaagac ctaatgcacc atttaattga actttacaag
    21001 agaggagtta aataaaatgg ataagttaat aatttttatt gagaaaggaa agcctttctt
    21061 tgagaaatta tcgagaaata tatacttaag agcgataaaa gatggtttta tttccagtat
    21121 gccagcagta ttattctcaa gtatttttat actaatagct gctgtgccca atatttttgg
    21181 gtttaaatgg tctgatgaac agttagcttt tattttgaaa ccttacaact actcaatggg
    21241 gattttagct ctcttagtag ctgggacaac tgcaaaatcg ttaacagatt cagttaatac
    21301 acgtagtatg gagaaaacca accaaatcaa ctacatgtca acttttttag cagctgttgt
    21361 tggattgtta atactggcag ctgatccaat tgaaggtgga tttgctaatg gtcttttagg
    21421 tactagagga ttacttactg catttttggc agcttttatt acagtaaata tctataaagt
    21481 atgtattaaa aataatgtaa ccattagact tcctgaagag gttccaccaa atattgcaca
    21541 agtttttaaa gatgttattc cgtttgcctt atctgttctt tcaatatatg gattggattt
    21601 aattgttaga aatatttttg gtacaaatgt agcagaatct gttggtaaaa tattagcccc
    21661 tctattttca gctactgatg gttatatcgg tttagctatt gtatttggtg cttatgcttt
    21721 cttttggttt gttggaattc atgggccatc tgttgtagaa cctttaattg tagctatcag
    21781 ttatgcaaat atagaagcta atgttcagct tgtgcaagct ggtatgcacg cagataaaat
    21841 tttaaatcca gttactcaaa cttttgttgt aacaatgggt ggtactggtg caacactagt
    21901 agttccattt atgtttatgt ggttatgtaa atcaaaaaga aatagaattg tcggacgtgc
    21961 gtctgtagtt cctactttct ttggcgtaaa tgaaccaatc ctatttggtg ctccaattgt
    22021 tttaaatcct atcttcttta ttccgtttgt tactgctcct attatcaatg tttggattat
    22081 gaaatttttt gtagatgttc tacaaatgaa tagtttcagt attattttac cttggacaac
    22141 acctgctcca attggtattg ttatgggaac ggcgctggct ccattgtcat tcgtcttggc
    22201 tataacttta atcattatcg acactttaat ctattatcca tttgttaaag tttatgacca
    22261 tcaaatttta gaagaagaac ggaaaggaaa ctcttcatct gaattgaaag aaaaagttgc
    22321 tgcaaacttc aacactgcaa aagcggatgc tattcttgaa aaagcaggtg tcgatgcagc
    22381 acaaaatacc atcactgaag aaacaaatgt cctcgttctc tgtgctggtg gaggtacaag
    22441 tggactcctt gcaaatgctt tgaataaggc agcagcagaa tacaatgtcc ctgtgaaagc
    22501 agcagcaggc ggctatggtg ctcaccgtga aatgttacca gagtttgatt tggttatcct
    22561 tgctcctcaa gttgcttcaa actttgaaga tatgaaggca gaaacagata agctcggtat
    22621 taaactagcg aaaacagaag gcgctcaata catcaaatta actcgtgatg gaaaaggtgc
    22681 cctagcattc gtacaagaac aattcgatta aggctaggaa ctgtgaaaca gtctcctatc
    22741 gttacggaaa tcgctatggc gaatttccta atcgccttat taattcgtcg gtaaaaagat
    22801 atcgttttta cctcctcatg tcacaattcg gtgacttggt acaagaagtg agatggagaa
    22861 ggatggctca ctgactcctc tcctctcact tttactttat ttaaatcaag aaataggtga
    22921 aaaaaatgac aaaaacactt ccaaaagact ttatttttgg tggcgcaaca gctgcctatc
    22981 aagcagaagg tgctacacat actgatggta aaggaccagt agcgtgggat aaatatcttg
    23041 aagataacta ctggtacact gcagaaccag ccagtgattt ttacaatcga tatccagttg
    23101 atctcaagct agcagaagag tatggtgtca atggcattcg aatttctatt gcctggtcac
    23161 gtattttccc gactggttat ggtcaagtaa atgctaaagg tgttgagttt tatcataatt
    23221 tatttgcaga gtgtcacaaa cgtcatgttg agccctttgt aactcttcat cactttgaca
    23281 cgccagaagc tctccactca aatggagact tcttaaaccg tgaaaatatc gaacattttg
    23341 tagactacgc tgccttctgt tttgaagaat ttccagaagt aaactattgg acaaccttca
    23401 atgaaattgg accaatcggt gatggtcaat atttggttgg gaaattccct ccaggtatcc
    23461 agtacgacct tgccaaagtc tttcaatcac accacaatat gatggtgtct catgcatgcg
    23521 cggtaaaatt gtacaaagag aaaggctata aaggggaaat tggtgttgtt cacgccctgc
    23581 ctactaaata tcctctagat cctgaaaatc cagcagatgt tcgtgcagca gagttggaag
    23641 atatcatcca caataaattc atcttagacg caacttatct aggtcgctat tcagctgaaa
    23701 ccatggaagg tgtcaaccat atcttatcag tcaatggtgg tagtttggat cttcgtgaag
    23761 aagattttac agcattagaa gctgcaaaag acttgaatga tttcctagga atcaactact
    23821 atatgagtga ctggatggaa gcctttgatg gagaaactga aattatccat aatggtaaag
    23881 gtgaaaaagg aagctctaag tatcaaatca aaggtattgg tcgtcgtgta gctcctgact
    23941 atgtatcacg cacggattgg gattggatta tctaccctca aggtttgtat gaccaaatca
    24001 tgcgtgtgaa gaaagattat cctaactaca agaagattta catcactgaa aatggtctcg
    24061 gctataaaga tgagttcgtt gataacactg tttacgatga tggtcgtatt gattacgtga
    24121 aacaacactt ggagatcttg tctgatgcga ttgcagatgg agctaatgta aaaggttact
    24181 tcatttggtc attaatggat gtcttctcat ggtcaaacgg ttatgagaaa cgttatggtc
    24241 tcttctacgt agattttgaa actcaagaac gttatcctaa gaaatcagct cactggtaca
    24301 agaaagtagc ggaaactcag attatagact agtagaatta gtcattagat atagaatttt
    24361 agtgagtcaa aaagatgttc aaagatttta tccaatctat ttatgaaaaa aagtttatat
    24421 tataaatttc gaaaaatgct ctcaaatacc gtgtttgacg agtgaagaat tgaaaagtct
    24481 tggaaaatgg tatgtctcga ctggtaaaga atggatttgt cattcagatg atgagctgga
    24541 agaatttaaa aatctatttt taaattttat caatcctgaa gaatgggata ctatctcctt
    24601 tgattcagat tttatgccgt ttcaacaatc gtaaccaatt tctcaaaaaa gttaaatctt
    24661 atatttagta ctctgtaaaa ctcttatcta atcacgttgc ttatactcaa tgaaaatcaa
    24721 agagcaactt taaactagga agcgagtcgc agatttctca atgcatagct ttgaggaatt
    24781 gggcaaaaag tctttgatat agaaaaaagc atagtatcag gtgttgaaac acctgatact
    24841 atgcttttta ttgtgggaag atttactttt tttcttctga aattgagttg ttacccaggc
    24901 tctttcagtt tattaaggct tgatgacttt aatgtgttta gatagcttaa aaaggattga
    24961 atcacttagt ttagaatctg aaacaatagt atcaagattt gatatattat aaaaagtata
    25021 aaaatcaaac ttattgaact tactatgatc tgcgagtaaa tattttttat tagaattatt
    25081 taaagcgatg cgttgagcct ctccctcttc ctcgctaaaa gtagctagag ctccgttttg
    25141 aataccatta cagctaacga aagctttaga aaattggaga ttagagagat tttgtagggt
    25201 caatgtgcca acaaaagcac ctgtaatatc gcgataattt ccacctatca aaatcaaatc
    25261 tgttaatttt cgttcgctta aaatcagaaa aacaggtaga ctgttggtta cgacgcggat
    25321 attgtcaata ggcaactcac gcgcaaaaaa ctctaatgtt gttcctggtc caatgaaaat
    25381 agtttctctt tcttctacta gactgcctgc aaaatgggct atttcttgtt tttctgccgt
    25441 ttggagggct tgtttttcaa tatttgatcg ctcattagtc aaaagggagt tggttcgaag
    25501 tttttcagct ccaccatgca cacgaatcag caaatcttta tcagctaatt cctgtaaata
    25561 gcgccttgca gtcatatctg aaacggctat ttcgtccata atctgtttaa ctgttatggt
    25621 tcctttacta tttactatct ctaaaatttt ggttaatttt tcttgtttga gcatattatc
    25681 acctcgtttc ctactactat cttaccataa acaaactcat cattcaaata caaaaacaac
    25741 aaaatgaaac aaaaacaaaa atatcgaagt ttgttttcaa aactttcgat atttttgttg
    25801 ggttattatt ttgttgtttc tagtttactt tttgatggtt aagagtggtg gagaattata
    25861 ctcaatgaaa atcaaagagc aaactaggaa gctagccgca ggctgtactt gagtacggca
    25921 aggcgaagct gacgtggttt gaatttgatt ttcgaagagt attagtccaa accgtagttg
    25981 tagtcatcat cttgcatggc ttcaacttcg ccaagaaggt aaccatttcc gacttgagag
    26041 aagaagtcat ggttggaagt tcctgttgaa ataccgttca taacgattgg gttgacatct
    26101 tcagctgaat ctgggaaaag tggatcttgt cccatgttca tgagagcttt attggcattg
    26161 tagcgaagga aggttttaac ctcttcagtc caaccaacac cgtcataaag actctctgtg
    26221 tagccttctt cattttcata aagagtatag agtaggtcgt acatccattc tttgagtttt
    26281 tcttgctctt cttcaggtaa ttcattgaaa ccaagttgga atttgtaacc aatgtaggtt
    26341 ccgtgaacag actcgtcacg aataatcaat ttaatgattt ctgcaacgtt ggcaagtttg
    26401 ttgttaccga gatagtagag gggagtgaag aaaccagagt agaagaggaa ggtttcgagg
    26461 aagacgctgg caactttctt ttcaagtggg ctgccgttta ggtagatttc gttgacaatc
    26521 tcagccttct tttgtaggta aggattggta ttggtccatt cgaaaatttc ttcaatctca
    26581 gccttagtat tcaaggtaga aaagattgat gagtaagatt tagcgtggac agattccata
    26641 aattggatgt tattgaaaac agcttcctca tgtggtgtac ggatgtctgc gcgaagggct
    26701 tgaaccccag tttcagattg catagtgtca agaagggtta aaccaccaaa aacttttccg
    26761 accaagtctt tctctttgtt agatagcttt ctccagtcat ccaagtcgtt tgataaggga
    26821 atacgtgtat cgagccaaaa ttgctccgtc agtttttccc aagttgattt gtcgatgaca
    26881 tcttcgatgg cattccagtt aatggctttg tagtaagttt ccatttaaaa tctctttctg
    26941 tgtttagtat tgcgaactca caattatttc tactttacca taattctata ggagtatcgc
    27001 acaaaaagtc ggaagcccga cttttaaaat gttacataaa ttatgttatg acatagtaga
    27061 tttgatttta tcagtgctgc ttagggaaaa atagtgtttc tatgctagaa actaaatcac
    27121 acagctttca cattggttgg cgccgacttc tccaccgtca tctgtaaagg tacggacgta
    27181 gtagatagac ttgattccct tgttaaaggc atagttacga aggatggaca agtcacgtgt
    27241 cgtttgttta ttttccctct tccattcgta aaggcctttt ggaatgtcac tacgcatgaa
    27301 gagggtgagt gaaagtcctt gatccacgtg ttcagtcgca gcagcgtaaa catcgatgac
    27361 tttacgcata tccatatcgt aggcagaagt gtagtaagga atggtttctg tagacaagcc
    27421 agcagcaggg tagtagattt taccaatttt cttttcctga cgttcttcaa tacgttgcgt
    27481 aatcgggtgg atagaagcag aaacatcgtt gatgtagctg atagaaccat ttggcgctac
    27541 agcaaggcga ttttggtggt aaagaccatc ctcttgaacc ttgtcgcgaa gttcagtcca
    27601 atcagcaaca ccagggataa aaacattttt gaagagttct ttaacacggt ctgatgttgg
    27661 aacaaattca ccagttacat acttgtcaaa gtaacttccg ttagcatagt ctgatttttc
    27721 aaagttgtgg aaggtaatac cacgttcacg cgcaatattg tttgactcta ccaaggtcca
    27781 gtagttcata agcataaagt agatgcttgt aaattcaaca gactcaggtg aaccatattc
    27841 aatgagttgt tgggcaaggt agctgtgcag tcccatggca ccgagaccaa aggtgtgggc
    27901 ttggctattt ccatggtcaa tcgttggtac agctacgata tgtgaactat ctgtaacgaa
    27961 agtaagggca cgaaccatag cacggataga acgaccaaaa tcaggtgaag tcatcatgtt
    28021 aaccacgttg gttgaaccca ggttacatga aacatctgtt cccatttgaa ggaattcttg
    28081 agcatcgttg atcaagcttg gttcttgaac ttgaagaatc tcagaacaca agttactcat
    28141 gataatcttt ccatcgacag gatttgcacg gttagccgta tctatgttga ctacataagg
    28201 atagccagac tcttgttgca atttagagat ttcagtttcc aaatcccgcg ccttgatttt
    28261 tgtcttgcga atatttggat ttgcgaccaa ttcatcgtat ttttcagtaa tgtcgatgta
    28321 attgaatggc acaccgtatt ctttttctac agagtaaggg ctgaagaggt acatttcttc
    28381 atttttacga gccaattcgt agaatttatc aggtactaca acaccaagtg atagagtctt
    28441 gacacgtact ttttcatcag cgttttcttt cttagttgaa aggaaagcga tgatatctgg
    28501 gtgaaagacg ttgaggtaga caacaccggc accttgacgt tgccccaatt ggttggagta
    28561 agagaagctg tcttcaaaaa gcttcataac aggaacgaca cctgaagcag ctccttcata
    28621 gcctttgata ggtgcaccag cttcacgaag gttgctgagg gtaattccca caccaccacc
    28681 aatacgtgaa agttgaagag ctgagttgat agaacgtccg atagagttca tatcatccgt
    28741 cacttggatt aggaaacaag ataccaactc cccacgacga gcacgtccag cattcaagaa
    28801 ggaaggagta gcaggttggt agcgttggtg gatgatttca ttggcaatat cgattgcaac
    28861 agcttcattc ccatcagcga aataaagggc gttgaagaag acacggtctt ccatattttc
    28921 aagatagtat tcaccgtcat tagtctttaa ggcatattga ttgtaaaatt tataagctgc
    28981 catgaatgac ttgaattgga agttttggtc tttgataaat tgagccaatt cttccaagaa
    29041 ctctggacgg tatttcttga taaaggctgt ttcgatgtag ttgtgttcaa tgaggtaatt
    29101 gattttgtct ttgattgaat caaaaaccat agtgtttgga actacatttt ctttaaagaa
    29161 agcatccaag gcttccttat ctttatgaag catgatttgt ccattaacag gacggttaat
    29221 ttcgttatta agacggaagt aagtcacgtc ttcaagatgt tttaatccca taaaatttcc
    29281 cttatctaat tacaaaagaa aggcttctaa gttagcccta aaagcagttt cttctggatg
    29341 atgtactaag attatgctaa ttgtttcagt ttttctggtt ggaaacctga aaagacttca
    29401 gttggtgttt ggataacagg agctgcgcta aaaccgagct ctttaacttg atcgacgtac
    29461 tcaggttgct catcaagatt gatttcacga taagagacat tattactgtc caagaaacgc
    29521 ttggtcattt tacattggac acaattgttt ttagaataaa cggttaccat tgtgtaactc
    29581 ctcttcaaaa tttaatacta tcttagtata tcagaaaata aaattttgtc aatgatttaa
    29641 actaaatata gtggtgttct tttgttgttt ttatatataa acacaatata tagtgtttgt
    29701 attgtgaaat agcaatgatt atcctataaa ttgtttttga agaaactata tcctgtgttt
    29761 tgttatctag gatagaagat tttcagcaag ttatctgaaa ggaaattgaa ggaaaatcca
    29821 gaaaatgctt gaaaaaaatc ctagaagatg gtataatact aaattgtaag ggttatcaca
    29881 tataactcaa aaaaagaaag aacaaaagga gagtcaaact atggcttcta aagatttcca
    29941 cgtagtggca gaaacaggta ttcacgcacg tccagcaaca ttgttggtac aaactgctag
    30001 caaatttgct tcagatatca ctcttgagta caaaggtaaa tcagttaacc ttaaatcaat
    30061 tatgggtgtt atgagtcttg gtgttggtca aggtgctgac gtaactatct cagctgaagg
    30121 tgcagatgca gatgacgcta tcgctgcaat ctcagaaaca atggaaaaag aaggattggc
    30181 ataagggaaa tgacagaaat gcttaaagga atcgcagcat ctgacggtgt tgcagttgca
    30241 aaagcatatc tactcgttca gccggatttg tcatttgaga ctattacagt cgaagataca
    30301 aacgcagaag aagctcgcct tgatgccgct ctacaggcat cacaagacga gctttctgtt
    30361 attcgcgaga aagcagtagg tacgctcggt gaagaagcag ctcaagtttt tgatgctcac
    30421 ttaatggttc ttgctgaccc agaaatgatc agccaaatca aggaaactat ccgtgcgaag
    30481 aaagtgaatg cagaagcagg tctgaaagaa gttacagata tgtttatcac tatctttgaa
    30541 ggcatggaag acaacccata catgcaagaa cgcgcagcgg atatccgcga cgtgacaaaa
    30601 cgtgtattgg caaaccttct tggtaaaaaa ttgccaaacc cagcttctat caatgaagaa
    30661 gtgattgtga ttgcgcatga cttgactcct tcagatacag ctcaattgga caaaaacttt
    30721 gtaaaagctt ttgtaaccaa cattggtgga cgtacaagcc actcagctat catggcacgt
    30781 acacttgaaa ttgctgctgt attaggtaca aacaacatca ctgaaatcgt taaagacggt
    30841 gacatccttg ctgttaacgg gatcactgga gaagtgatta tcaacccgac agatgaacaa
    30901 gcggcagaat ttaaagcagc tggtgaagcc tatgcgaaac aaaaagctga atgggcactt
    30961 ttgaaagatg ctcaaacagt gactgctgac ggtaaacact tcgagttggc tgccaatatt
    31021 ggtactccaa aagacgttga aggtgttaac aacaacggtg cagaagctgt tggactttac
    31081 cgtacagagt tcttgtacat ggattctcaa gacttcccaa ctgaagatga gcagtatgaa
    31141 gcatacaagg ctgttcttga aggaatgaac ggtaaacctg ttgtcgttcg tacaatggat
    31201 atcggtggag ataaggaact tccttacttc gatatgcctc acgaaatgaa cccattcctt
    31261 ggattccgtg ctcttcgtat ctctatctct gagactggag atgctatgtt ccgcacacaa
    31321 atccgtgctc ttcttcgtgc gtctgttcac ggtcaattgc gtatcatgtt cccaatggtt
    31381 gcgctcttga aagaattccg tgcagcgaaa gcagtctttg atgaagaaaa agcaaacctt
    31441 cttgctgaag gtgttgcagt tgcggataac atccaagttg gtatcatgat cgagattcct
    31501 gcagcggcta tgcttgcaga ccaatttgct aaagaagttg acttcttctc aattggtaca
    31561 aacgacttga tccaatatac aatggcagca gaccgtatga acgaacaagt ttcatacctt
    31621 taccaaccat acaacccatc aatcctacgc ttgattaaca atgtgatcaa agcagctcac
    31681 gctgaaggta aatgggctgg tatgtgtggt gagatggctg gtgaccaaca agctgttcca
    31741 cttcttgtcg gaatgggctt ggatgagttc tctatgtcag caacatctgt acttcgtaca
    31801 cgcagcttga tgaagaaact cgacacagct aagatggaag agtacgcaaa ccgtgccctt
    31861 acagaatgct caacaatgga agaagttctt gaacttcaaa aagaatacgt taattttgat
    31921 taatcgaaaa gtccctgcaa ctcagttaca gggacttttt ttgatatttt aaaaagaatt
    31981 ttcaagaaaa tctttcttat aaaaagtcca accttgaaaa agtagtggtc agaacaaaaa
    32041 atacttaaat ggttcataaa attcttgaca agttggagat ttaggagtaa actattaacc
    32101 agttaagtaa tagagaggag tttctgcaat ttagaaatga attgcaacta gaaatatcaa
    32161 atagaaagag agtttcgatg aaaattaata agaaatacct tgttggttct gcggcagctt
    32221 tgattttaag tgtttgttct tacgagttgg gactgtatca agctagaacg gttaaggaaa
    32281 ataatcgtgt ttcctatata gatggaaaac aagcgacgca aaaaacggag aatttgactc
    32341 ctgatgaggt tagcaagcgt gaaggaatca atgctgagca aatcgtcatc aagataacag
    32401 accaaggcta tgtcacttca catggcgacc actatcatta ttacaatggt aaggttcctt
    32461 atgatgcgat tttcagtgaa gaattactca tgaaagatcc aaactataag ctaaaagatg
    32521 aggatattgt taatgaggtc aagggtggat atgttatcaa ggtagatgga aaatactatg
    32581 tttaccttaa ggatgcagct catgcggata atgtccgtac aaaagaagaa atcaatcggc
    32641 aaaaacaaga acatagtcag catcgtgaag gagggacttc aacaaacgat ggtgcggtag
    32701 cctttgcacg ttcacaagga cgctatacta cagatgatgg ttatatcttt aatgcttctg
    32761 atatcattga ggacacgggt gatgcttata tcgttcctca cggcgaccat taccattaca
    32821 ttcctaagaa tgagttatca gctagcgagt tagctgctgc agaagccttc ctatctggtc
    32881 ggggaaatct gtcaaattca agaacctatc gccgacaaaa tagcgataac acttcaagaa
    32941 caaactggct accttctgta agcaatccag gaactacaaa tactaacaca agcaacaaca
    33001 gcaacactaa cagtcaagca agtcaaagta atgacattga tagtctcttg aaacagctct
    33061 acaaactgcc tttgagtcaa cgccatgtag aatctgatgg ccttgttttc gacccagcgc
    33121 aaatcacaag tcgaaccgcc agaggtgtag ctgtccctca tggtaaccat taccacttta
    33181 tcccttatga acaaatgtct gaattggaaa aacgaattgc tcgtattatt ccccttcgtt
    33241 atcgttcaaa ccattgggta ccagattcaa gaccagaaca accaagtcca caatcgactc
    33301 cggaacctag tccaagtctg caacctgcac caaatcctca accagctcca agcaatccaa
    33361 ttgatgagaa attggtcaaa gaagctgttc gaaaagtagg cgatggttat gtctttgagg
    33421 agaatggagt ttctcgttat atcccagcca aggatctttc agcagaaaca gcagcaggca
    33481 ttgatagcaa actggccaag caggaaagtt tatcgcataa gctaggagct aagaaaactg
    33541 acctcccatc tagtgataga gaattttaca ataagactta tgacttacta gcaagaattc
    33601 accaagattt acttgataat aaaggtcgac aagttgattt tgagg
//
LOCUS       DAVLBE010000020        32885 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.020, whole genome shotgun sequence.
ACCESSION   DAVLBE010000020 DAVLBE010000000
VERSION     DAVLBE010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 32885)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32885)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32885
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.020"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(603..1292)
                     /gene="rplA"
                     /locus_tag="VXB91_000987"
     CDS             complement(603..1292)
                     /gene="rplA"
                     /locus_tag="VXB91_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HEV0470460.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKVKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
     gene            complement(1500..1925)
                     /gene="rplK"
                     /locus_tag="VXB91_000988"
     CDS             complement(1500..1925)
                     /gene="rplK"
                     /locus_tag="VXB91_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HEV0470461.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAMRMIEGTARSMGFTVVD"
     gene            complement(2048..2764)
                     /locus_tag="VXB91_000989"
     CDS             complement(2048..2764)
                     /locus_tag="VXB91_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HEV0470462.1"
                     /translation="MKKRYVILSGLLALTLAACSQEKTKVEENTQKTEQSSQPEGTVG
                     SKSQASSQKKAEVSNKGSYYSIQGKYDEIILANKRYPLSKDYNPGENPTAKAELLKLI
                     AAMQAEGYPISDQYSGFRSYETQAKLYQDYVNQDGKEAADRYSARPGYSEHQTGLAFD
                     LIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AASGLSLEEYYGFEGGDYVD"
     gene            complement(2782..3243)
                     /locus_tag="VXB91_000990"
     CDS             complement(2782..3243)
                     /locus_tag="VXB91_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000335612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEV0470463.1"
                     /translation="MCLICQRIELIKAGQNPYFVKELETGYVVIGDYQYFKGYTLFLA
                     KDHVTELHHMETSVKLRFLEEMSLVQEAVAKAFEAEKMNIELLGNGDAHAHWHLFPRR
                     AGDMKSHGLNGRGPVWWVPWEEMAAEDCQVQSPELEEMIKILSHELEKYLA"
     gene            complement(3245..4282)
                     /locus_tag="VXB91_000991"
     CDS             complement(3245..4282)
                     /locus_tag="VXB91_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HEV0470464.1"
                     /translation="MNQTVEYIKELTAIASPTGFTREISNYLVKTLEGFGYQPVRTAK
                     GGVNVTIKGQNDEQHRYVTAHVDTLGAIVRAVKPDGRLKLDRIGGFPWNMIEGENCTV
                     HVASTGQKVSGTILIHQTSCHVYKDAGTAERTQDNMEVRLDVKVSNEKETRALGIEVG
                     DFISFDTRTVVTDTGFIKSRHLDDKVSAAILLNLLRIYKKEKIELPVTTHFAFSVFEE
                     VGHGANSNIPAQVVEYLAVDMGAMGDDQQTDEYTVSICVKDASGPYHYDFRQHLVALA
                     KEQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVIATERM
                     VDAYLKSEAVS"
     gene            complement(4380..5705)
                     /gene="brnQ"
                     /locus_tag="VXB91_000992"
     CDS             complement(4380..5705)
                     /gene="brnQ"
                     /locus_tag="VXB91_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HEV0470465.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAAAYLISLNPSKILDRIGRVLTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVVGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            complement(5876..5968)
                     /locus_tag="VXB91_000993"
     CDS             complement(5876..5968)
                     /locus_tag="VXB91_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV0470466.1"
                     /translation="MRSARACQFLLEQGYNVINVQGGMLAFEEL"
     gene            complement(6011..6163)
                     /locus_tag="VXB91_000994"
     CDS             complement(6011..6163)
                     /locus_tag="VXB91_000994"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV0470467.1"
                     /translation="MKEIAFDAFYQLYQNDQLSLVDVREVDEFAALHLECAHNLPLSQ
                     LADSYD"
     gene            complement(6323..6901)
                     /locus_tag="VXB91_000995"
     CDS             complement(6323..6901)
                     /locus_tag="VXB91_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HEV0470468.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFAAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPRT
                     GFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFPLV
                     HPSPRNQIWMAKNPWFEAEVVPDLKKRIKTIL"
     gene            complement(6955..8355)
                     /gene="pepV"
                     /locus_tag="VXB91_000996"
     CDS             complement(6955..8355)
                     /gene="pepV"
                     /locus_tag="VXB91_000996"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HEV0470469.1"
                     /translation="MTAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGVARLHSFTGGLREN
                     MVPESATAVVSGDLADLQAKLDAFVAEHKLRGELQEEAGKYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFGFAGPAKDYLDIAGKILLNDHEGENLKIAHVDEKMGALSMNAGV
                     FRFDETSADNTIALNIRYPKGTSPEQIKSILENLPVVSVSLSEHGHTPHYVPMEDPLV
                     QTLLNIYEKQTGFKGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            complement(8368..8973)
                     /locus_tag="VXB91_000997"
     CDS             complement(8368..8973)
                     /locus_tag="VXB91_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEV0470470.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDPKDVRTAIEIATLAPSAHNSQP
                     WKFVVVREKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYNEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDEKLEPSYRLPVDEIIEKR"
     gene            9144..9944
                     /locus_tag="VXB91_000998"
     CDS             9144..9944
                     /locus_tag="VXB91_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0470471.1"
                     /translation="MKKFSLLLAILPFLVACGNQATPKETSAQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTSLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATINFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSADSPSN
                     YIIFSSDQKEFKEQFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
     gene            complement(10128..10961)
                     /locus_tag="VXB91_000999"
                     /pseudo
     CDS             complement(10128..10961)
                     /locus_tag="VXB91_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
     gene            complement(10951..12798)
                     /gene="uvrC"
                     /locus_tag="VXB91_001000"
     CDS             complement(10951..12798)
                     /gene="uvrC"
                     /locus_tag="VXB91_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HEV0470472.1"
                     /translation="MNNLIKSKLELLPTSPGCYIHKDKNGSIIYVGKAKNLRNRVRSY
                     FRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKKDEAYFKSMAQEVSDFLKGQDNKIIDELKGKMAAAAQTMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDTKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGRPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMRHFKSLTKIKEA
                     SVDEIVEVGVPRAVAEAVQTKLNPQETEILLQVAEERVDYQTEGNHNKP"
     gene            complement(12838..13539)
                     /locus_tag="VXB91_001001"
     CDS             complement(12838..13539)
                     /locus_tag="VXB91_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="matrixin family metalloprotease"
                     /protein_id="HEV0470473.1"
                     /translation="MRWLFRLIGAFFSFVWRLFWRLVWIVVLLCVLAFGLLWYLNGDF
                     QGALKQAERSVKIGQQSIDQWEKTGQLPKLSQTDSHQHSEGRWAQASARIYLDPQMDS
                     RFQEAYLEAIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTNLLAGQ
                     FLSVTVRLNHYYLSNPHYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVANLRKIYETSE"
     gene            complement(13618..14850)
                     /gene="murN"
                     /locus_tag="VXB91_001002"
     CDS             complement(13618..14850)
                     /gene="murN"
                     /locus_tag="VXB91_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HEV0470474.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEYFYDTFGEQAEFLIASLNFSEYMSKLQGEQSKLEENLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(14855..16075)
                     /gene="murM"
                     /locus_tag="VXB91_001003"
     CDS             complement(14855..16075)
                     /gene="murM"
                     /locus_tag="VXB91_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HEV0470475.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFVIQSIKSYARSKRAV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRTSKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMVWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            complement(16187..16966)
                     /locus_tag="VXB91_001004"
     CDS             complement(16187..16966)
                     /locus_tag="VXB91_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEV0470476.1"
                     /translation="MAVMKIEYYSQVLDMEWGVNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYTALAEELPQVLK
                     RFFPNMTSKREKTFIAGLSMGGYGCFKLALATNRFSHAASFSGALSFQNFSPESQNLG
                     SPAYWRGVFGEIKDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            complement(17035..18696)
                     /locus_tag="VXB91_001005"
     CDS             complement(17035..18696)
                     /locus_tag="VXB91_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEV0470477.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPEHIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKVLSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILRESSELINQT
                     VEEYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(18871..21093)
                     /gene="recJ"
                     /locus_tag="VXB91_001006"
     CDS             complement(18871..21093)
                     /gene="recJ"
                     /locus_tag="VXB91_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HEV0470478.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQDQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEERENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSMPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIAANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIALMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPHRDLFIAFGGHAGAAGMTLEVEQLSDLSQVLEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GGASFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMVDARVEGVQLFN
                     IRGKNAVLPEGVPVLDFPGELPNLAASEAIVVKNIPEDITQLKTIFQEQHFSAVYFKN
                     DIDKAYYLTGYGTRDQFAKLYKTIYQFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            21370..22128
                     /locus_tag="VXB91_001007"
     CDS             21370..22128
                     /locus_tag="VXB91_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV0470479.1"
                     /translation="MALVEFKNVEKYYGDYHALRNINLRFEKGQVVVLLGPSGSGKST
                     LIRTINGLEAVDKGSLLVNGHQVAGASQKDLVPLRKEVGMVFQHFNLYPHKTVLENVT
                     LAPIKVLGIDKKEAEKTAKKYLEFVNMWDKKDSYPAMLSGGQKQRIAIARGLAMHPEL
                     LLFDEPTSALDPETIGDVLAVMQKLARDGMNMIIVTHEMGFAREVADRIIFMADGEVL
                     VDTTDVDNFFDNPSEPRAQQFLSKIINHESDKVK"
     gene            22168..22932
                     /locus_tag="VXB91_001008"
     CDS             22168..22932
                     /locus_tag="VXB91_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEV0470480.1"
                     /translation="MISLFGLAAAKPVQADTSIADIQKRGELVVGVKQDVPNFGYKDP
                     KTGTYSGIETDLAKMVADELKVKIRYVPVTAQTRGPLLDNEQGDMDIATFTITDERKK
                     LYNFTSPYYTDASGFLVNKSAKIKKIEDLNGKTIGVAQGSITQRLITELGKKKGLKFK
                     FVELGSYPELITSLHAHRIDAFSVDRSILSGYTSKRTALLDDSFKPSDYGIVTKKSNT
                     EFNDYLDNLVTKWSKDGSLQKLYDRYKLKPSSHTAD"
     gene            22945..23622
                     /locus_tag="VXB91_001009"
     CDS             22945..23622
                     /locus_tag="VXB91_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV0470481.1"
                     /translation="MTDLSSWTAYFQDFGQFFNGFLFTLALAIGSFILAMVLGIFFGA
                     MSTSKRPILRILARIFVEFYQNTPLLVQFVIVFYGLPLISDHTIMIPIYWTAVLCVGL
                     YHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLIILPQTFRIILPPLTNQIVN
                     LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPAFLGAALLYFALCFPVAQFGRKMEQA
                     NKKAYSL"
     gene            23632..24291
                     /locus_tag="VXB91_001010"
     CDS             23632..24291
                     /locus_tag="VXB91_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV0470482.1"
                     /translation="MESILEVLTPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVM
                     RNGKNSVLRIISSIYIEFVRNVPNLLWIFTIFLVFKMKSTPAGITAFTLFTSAALAEI
                     IRGGLNAVDKGQYEAGMSQGFTSAQILYYIILPQAIRKMLPAIISQFVTVIKDTSLLY
                     SVIALQELFGASQILMGRYFEPEQVFSLYILIALIYFSFNLAISSLSHMLAKRWQQAA
                     E"
     gene            24587..25777
                     /locus_tag="VXB91_001011"
     CDS             24587..25777
                     /locus_tag="VXB91_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HEV0470483.1"
                     /translation="MKSVKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSLTFIL
                     ATRLPLLESWFHGLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNLAIYI
                     FASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFLVGSY
                     ALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLSRPFNYQSGQFAFLK
                     IFQEGFESAPHPFSISGGHGQTLYFTVKNSGDHTNNIYDNLQAGSKVTLDRAYGHMII
                     EEGRENQVWIAGGIGITPFISYIREHPILDKQVHFYYSFRGDENAVYLDLLRNYAQKN
                     PNFELHLIDSTKDGYLNFEQKEVPEHATVYMCGPISMMKALAKQIKKQNPKTELIYEG
                     FKFK"
     gene            complement(26098..26979)
                     /locus_tag="VXB91_001012"
     CDS             complement(26098..26979)
                     /locus_tag="VXB91_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HEV0470484.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(27120..28448)
                     /gene="vncS"
                     /locus_tag="VXB91_001013"
     CDS             complement(27120..28448)
                     /gene="vncS"
                     /locus_tag="VXB91_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HEV0470485.1"
                     /translation="MKRTGLFAKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGGTMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMDLDSQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKDRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTQNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENRLTFFIAFPKVAQD"
     gene            complement(28445..29101)
                     /gene="vncR"
                     /locus_tag="VXB91_001014"
     CDS             complement(28445..29101)
                     /gene="vncR"
                     /locus_tag="VXB91_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HEV0470486.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASLAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCILTVRNVGYKLERK
                     "
     gene            complement(29150..29233)
                     /gene="pep27"
                     /locus_tag="VXB91_001015"
     CDS             complement(29150..29233)
                     /gene="pep27"
                     /locus_tag="VXB91_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198523890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HEV0470487.1"
                     /translation="MRKEFHNVLSSDQLLTDKRPARDYNRK"
     gene            complement(29413..30792)
                     /gene="vex3"
                     /locus_tag="VXB91_001016"
     CDS             complement(29413..30792)
                     /gene="vex3"
                     /locus_tag="VXB91_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HEV0470488.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(30844..31491)
                     /gene="vex2"
                     /locus_tag="VXB91_001017"
     CDS             complement(30844..31491)
                     /gene="vex2"
                     /locus_tag="VXB91_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HEV0470489.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQINYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIR
                     LVNKKASKNTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(31504..32781)
                     /locus_tag="VXB91_001018"
     CDS             complement(31504..32781)
                     /locus_tag="VXB91_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0470490.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGNSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNGITTYLLQTLLASGDQASLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
BASE COUNT         9278 a         7544 c         6132 g         9931 t
ORIGIN      
        1 aagagtatta gaaagctcga tggactattc cagattcatt ccactagatt tcgaaatcga
       61 gtaggggata atctctagcc cctctcacac caccgtacgt gccgttcggc atacggcggt
      121 tcaactaact tttaacgcat gtcgttcaag gtaataatcc aaacacgaaa ccagtccacg
      181 tttttcaagg actggttttg atatagcacg tttaagtacc gacttctgag ctactatagt
      241 agattgaaac tagaatagta cacctctact tctaaaacat tgttagaaat cgatttgact
      301 gtcctgaacg attcgtccta ttcttatttc attttattat aattgatagt ggtcgcccca
      361 gccagatacc ttatccgcta tataggcctt attatcacgt tcctgttcgt agagccacga
      421 tttcgctatc ccttcctctg acgattctta tttccagcgt cagacttggg aatcgctatt
      481 gggttcaccg gtagtaggtg cccaccgagg acttacacct cagatatacg acatgcccgt
      541 cgtacatcaa aaaaagttga gacatagtgt cttcaacttt tttacattac tttaactact
      601 gattaaagtg agtttacgtc aactttgata ccaacacctt gagtagttgt gatagtcaag
      661 tttgttacgt aagttccttt agctgtagct ggttttactt tttggattgt ttcgttgaaa
      721 gctttaaagt tttcaaccaa tttttcagct tcaaatgata ctttaccgat gattgcttga
      781 acgttacctg cacggtcagc acggtaagtg attttaccac ctttagactc ttcaactgct
      841 ttagcaacat ccattgttac agtaccagtt ttagggtttg gcatcaagtt acgtggtcca
      901 aggacacgtc caagacgtcc aacaagagcc atcatatcag gtgtagcgat aactacgtcg
      961 aagtccaacc aaccgtcgtt gattttagca acaaggtcat cttcaccaac aaagtctgca
     1021 ccagcagctt ttgcttcttc agcttttgca ccacgtgcga aaacaagaac acgtgaagtt
     1081 ttaccagtac cgtttggcaa taccattgct ccacggattt gttggtcagc ttttttaacg
     1141 tcgatgttca agttgtaagc aacttctaca gttgcatcaa attttgcaaa gttagtttct
     1201 tttgcaagtg ctacagcttc ttctacactg tatgcttttg tgctgtcgat tttctcaaga
     1261 gcagcacgaa gttgtttgct ttttttagcc attttctatt ctccttgtaa gtggttcaat
     1321 cgattttcat ctcccacgtc acttctcgaa atgatgaagt cttgcgggtt ttcagtctac
     1381 tatttttctc ttcctacggc cttaagctcc cttgctgtat ccaagtacaa gcctcagtca
     1441 cttgcctagt atgaaaagca actaatagac tgctgtgaga ttttctactg tgttattgat
     1501 tagtcaacaa cagtgaatcc catagaacga gcagtacctt cgatcatacg cattgcagac
     1561 tctacgtttg ctgcgttcaa atctggcatc ttagtttctg caatttcttg tacttgtgca
     1621 cgagtaactg tagcaacttt agttttatta ggtgtacctg atcctttttc aacacctgca
     1681 gcttttttca aaagaacagc agctggtggt gttttcgtaa cgaaagtaaa tgatttatct
     1741 tcgtaaactg agataacaac tggaatgatc ataccagctt ggtcagctgt acgagcgttg
     1801 aactcttttg tgaatcccat gatgttgata ccagcttgac caagagcagg tccaaccggt
     1861 ggagctggtg tagctttacc agcagggatt tgcaatttta caagtttttc gactttttta
     1921 gccattttta aatcctcctt tgtggttttg gcggtaatta gagattttta cctcccacaa
     1981 gtatgcttta cacatacctt tccattatac actatttatc taaaaatgca agagaaaact
     2041 ttcattttta atcgacataa tcgccgcctt caaagccata gtactcttcc aaactgagac
     2101 cacttgcagc aatttctttg gcttcttttc caacgtagcg gagatgccat tcttctgcca
     2161 tgtagccagt ctccttttcc ttgcctttaa gatagcgaac aacaaagcca tagtcagccg
     2221 catggtccaa gagccactgg gctgcctttt cttcagtaac taaatcccca tctgtcccaa
     2281 tcaaatcaaa agcaagaccc gtctggtgtt cactgtaacc tgggcgtgct gagtagcgat
     2341 ctgctgcttc cttaccatct tgattgacat agtcttggta gagcttagcc tgagtttcat
     2401 aactcctaaa cccactgtat tggtcactga ttggatagcc ctcagcctgc atagctgcga
     2461 ttagtttgag caactctgcc ttggctgttg gattttctcc tggattgtaa tcttttgaca
     2521 aaggataacg tttattagct aggataatct catcgtattt cccttggata ctataatagc
     2581 tccctttatt gctaacttct gcctttttct gactagaagc ttgagatttg ctacctacag
     2641 ttccttccgg ttgactgctt tgctccgttt tttgagtgtt ttcttcaact ttggtttttt
     2701 cttgcgaaca agctgcaagg gtcaatgcta gtaaaccaga taaaatgaca tatctttttt
     2761 tcatttcttt cttcctctct cttaggccaa atacttctcc aattcatgag ataagatttt
     2821 aatcatctct tccagctctg gcgattgtac ttggcaatct tctgccgcca tttcttccca
     2881 gggcacccac cagactgggc cacggccatt caaaccgtga ctcttcatat cacctgctct
     2941 tcggggaaaa agatgccaat gagcgtgggc atcgccattt cctaggagtt caatattcat
     3001 cttttcagcc tcaaatgctt tggcgactgc ttcttggact aaactcattt cctctaaaaa
     3061 gcgaagtttt acagaagttt ccatatgatg gagttctgtg acatgatctt ttgctaaaaa
     3121 taaggtatag cccttaaagt attggtagtc accaataaca acatagcctg tttctagttc
     3181 ttttacaaag tagggatttt gcccagcttt aatgagttcg attctctgac agattaagca
     3241 cattctatga taccgcctcg ctcttaagat aagcatcaac catacgctca gtcgctatta
     3301 ctgaatcgat gtgggtgcgc tcataagagt gactggactc aataccagct ccaagaagtg
     3361 catgcttgac ctctgcacct gctgacatcg ctgctgaagc gtccgatccg taaaatggat
     3421 agatgtcgag cttaaatgga atatcttgct ctttagccaa ggcaaccaag tgttgacgga
     3481 agtcatagtg ataaggacct gaagcatcct tgacacagat agatactgtg tactcatctg
     3541 tctgctggtc atctcccata gctcccatat ccacagccag atattctact acctgagcag
     3601 gaatgttaga attagcacca tgtcctactt cttcaaaaac tgaaaaagca aaatgagttg
     3661 ttactggcaa ttcaatcttc tctttcttat aaatacgaag caggttgagc aaaatcgctg
     3721 cgctgacctt atcatccaaa tgacgagact tgataaaacc tgtatcagtc acaacagttc
     3781 gtgtatcgaa gctgataaaa tcaccgacct caatcccaag agcacgagtt tctttttcat
     3841 tgcttacttt tacatccaaa cgcacttcca tattgtcctg cgtgcgttct gcagttcctg
     3901 catccttgta gacatggcaa gaagtttggt ggatgaggat ggttcctgat accttttgac
     3961 ctgtgctagc cacatgaacg gtacagtttt caccttcaat catgttccaa ggaaaaccac
     4021 cgatacggtc caatttaaga cgaccatctg gtttgacagc acgaacaata gcacccagcg
     4081 tatccacatg ggcagtcaca tagcgatgtt gctcatcatt ttgacctttg atggtcacat
     4141 tgacaccacc cttagctgtg cgaactggct ggtaaccaaa accttctaga gtcttgacta
     4201 aataattcga aatttcacga gtgaagcccg ttggcgatgc gatggctgtc agttctttga
     4261 tatattctac tgtttgattc atttcttcac ctctttcgct acctattata acacatttat
     4321 catcggataa aaaaagaaaa tcactcctgt agacttggct acaaaagtga tttaagtgat
     4381 tattccattt caaaaacatc gctttcttgc ttgtttggta gaaccaatga gagcaagatt
     4441 ccaacaatgg ctggcaccaa ccatgggaga gatgccttgg caaaaggaag aacgctaaca
     4501 agatttgcaa gaaactcaac cttaaacgag cttcctagta cgcttgcaat ggcaataact
     4561 gtaaccacag caattgtcaa ctgcatacct ggttttgaaa gggcaacaaa tttgttgaca
     4621 atgacaatca taacgatagc aatcgtgatt gggtacaaga taaccagtac tggaattgag
     4681 tacttgataa tcgcatcaag acccaaattg gcaatagcaa atccaatcaa ggtaaaggct
     4741 gtcgcataaa ccttgtagct gatttgtggg aagcgctcat taaagaactc agctgttgac
     4801 acaatcaaac caacagtcgt tgtgaagcag gttacggtaa ccatagctgc aaggaagagt
     4861 tgagctgttg agccaaagat ttcttgagtg gcttgtgaca agatgtaaac acctggtgtt
     4921 ccacccttca tcgcttcagc tggtactggg aaatgatttc caagaaaacc taaaccgatg
     4981 taaagagcgc tgaaggcaag ggcaacaacg ataccaacaa cccaaatagt tgaaatgtat
     5041 tctttcttac ttgaaaatcc aagttgtttc aaggtttgaa ctgcgattac gctaaaggcc
     5101 actgaagcaa gggcgtccaa ggtattgtaa ccttctagga aacctgtacc aaaggcagaa
     5161 gcttgataag cagctgaagc agcttgagga cttgttccac catatttgat agctcccaga
     5221 acgaccaaga taacaatcaa aattgcaaag actggcgtta aaacacgtcc aatgcggtct
     5281 aagatttttg atggattaag cgaaatcaaa taggctgccg caaaatacag aaccgtaaat
     5341 acaatcaagc caagtccttt atttgcatcc gacaaaaggg ggctaatccc tacttcgtaa
     5401 gctgttgtag cagtacgtgg ggtagcaaag aatggaccga ttgacaagta aagaactgag
     5461 aggtaaagag tcgcaaacca aggcgctatc ttcgttgaaa tctcgtagat atatccttta
     5521 ggatttagcg ttccaataat aagggtcaag acggcgatac caacgcctga aaagacaaaa
     5581 cctgcgatgg caggaagaaa atgttctcca gatagagcac ctagagaagg cggaaaaatc
     5641 aagttccccg caccaaaaaa tattccaaac aggagcaaac ctgttagggt acctttttta
     5701 gccataaaaa tctccttcat atttataaaa tactgaccta gtataccacg attaggagtc
     5761 tgaaaaaagc atcacgaggc aaatattaaa tgttttcaat tttcttaaaa ataagaatta
     5821 tctaaaaata aaactctcct acccagtcca caccaagcag gagaaatgca aaattttaaa
     5881 gttcttcaaa ggctaacatg ccaccctgga cattgataac attataacct tgttctaaca
     5941 ggaattggca agcacgcgcc gatctcattc cagatttgca aataatataa tgcaagcgat
     6001 ctttgtccaa ttaatcataa ctatcagcca attgactaag cggtaggttg tgggcacatt
     6061 ctaaatgaag agctgcaaac tcatccactt ctctcacatc cactagagaa agctggtcgt
     6121 tttggtaaag ctggtaaaat gcgtcaaagg ctatttcttt cattcttttt cttctaatac
     6181 tcttcgaaaa tctcttcaaa ccacgtcagc gtcgccttac cgtgcgtatg ttaccgactt
     6241 cgtcagtttt atctgcaacc tcaaagctgt actttgagca gcctacgact agcttcctag
     6301 tttgctcttt gattttcatt gactataaaa tggttttaat tctttttttc aaatctggca
     6361 ctacttctgc ctcaaaccaa ggatttttgg ccatccagat ttgatttcgt ggtgatgggt
     6421 gaactagcgg aaaataggct ggcagatagt ctttatagtg tttcaccctc tccgttacct
     6481 tcccactgat tttctcctgt aaatagtagg cttgggcata ttgcccaatc aagagggtta
     6541 actgaatatc aggcaattcc tgtaagagct gcggatgcca tttttctgca aaacctgtac
     6601 gaggcggaag atcacccgac ttgccatgtc ctggaaagta gaaatccata ggcaaaacag
     6661 caaaataacc tgaattgtaa aaggtatctt catccacacc tagccagtcc cgcaagcggt
     6721 caccactttt atctttccag taaaggcctg cttcttgagt tttaagtccc ggagcctgac
     6781 cgatgatatt gatgcgagca gtttttggcg ctgcaaagag aggctcaatg ccacgctctg
     6841 tatagctggc attctgtgaa tccgccatga tagcctgttt gattctttcg atttgagaca
     6901 tctactttcc ctccaaaaag aagtccaagc ataagatctc agacttctat cgttttattt
     6961 gatcaattcg taaatagctt cggcatagat tgctgctgct cggaagagat cgtccaaggc
     7021 gataaattca ttggcttggt gcatggtatc aattgagtct gggaacatag caccataggc
     7081 aactccgcgc tctaacaagc gaccaaaggt tccaccaccg atgacttgtt catgaccttt
     7141 aaagccagtt tgtttttcat agatattcaa caaggtttgc acaagtggat cttccattgg
     7201 cacatagtga ggcgtgtgac cgtgttcaga caggctaaca gaaacaactg gcaagttttc
     7261 aaggattgac ttgatttgtt ctggacttgt tccttttgga tagcggatgt tgagggcaat
     7321 ggtattatca gcacttgttt catcgaagcg gaagacgccg gcattcatag aaagagcacc
     7381 catcttttca tccacatgag caatcttaag attttcaccc tcatgatcgt tcaagagaat
     7441 tttacctgcg atgtcaaggt agtctttggc tggaccagca aagccaaact gactgaggaa
     7501 gagggcaagg taagttgcgc cattgacacc tgaagcaggc atagcaccgt gggctgattt
     7561 accaatgatc gtcaccttgt atttgccagc ttcttcttgg agttctcctc taagtttgtg
     7621 ttctgcaaca aaggcatcta gtttagcttg caagtcagcc aagtcacctg aaacgactgc
     7681 tgttgctgat tctggtacca tattttcacg taaaccacct gtaaagctgt gaagacgggc
     7741 aacacctgta ttttctcctg caaagtggag gtattccgtg atatttcctt tttcaccatt
     7801 gatgattgga aattcagcat ctggtgagaa accgaaatct ggtttggcaa gtcctacgtg
     7861 ctcaaagtag tagtccatgt ctgcccagcc tgattcttcg tctgttccaa cgatgaagcg
     7921 aactttctta gaagttggaa gacccaattc tttgatgatt ttcaaaccat agtaacaagc
     7981 tgttgtagga cccttatcgt ccgaagcccc gcgcgcataa aggcgaccat ctttgatagt
     8041 tggtgtgtaa gggtctgtgt cccaaccgct accagcaggc accacatcca tatgggcaaa
     8101 gattccgaga acttcttctc catcaccaaa ctcaaaatgt cctgcatagt tatcaacatt
     8161 cttagttggg tagccatcgc ggtctgcgat ttcaaggaat ttctccaagg cttttactgg
     8221 accaggccca aatggatgct gggcatcagc cttgctgtca tcacgttctg aattgatttc
     8281 caaaaggcta aacaagtcag ccaagaggtc ttctttgcgt ttttctactt ctgctgtaaa
     8341 atcaattgct gtcatttttt cttctttcta tcttttctcg atgatttcat ctactggcaa
     8401 gcggtagctt ggttccaatt tttcgtctgt ataacccact gtgatcaaga gttctgggcg
     8461 gaaacggtct tcgatttcca aaacttcatt aacttttgat ttgtcaaaac caagaataat
     8521 gttagaacca attccttggt ctgtcaatgc aagaaccaag ttcatggcaa ccaaacctgc
     8581 attgagagct aggtagtcgc tgacttgttg ttcattgtag cgtgcaaatt cagctggcaa
     8641 atttttcatg aagtattgaa gttgttcttc tgagaaattg ttagcaccac caactcgggc
     8701 aatcttacga gcgcgtttgg caaggtctgt atctgtaaat agggcaatgg ttacaggtgc
     8761 tgatgatacc tgctcaaagt ttgaaccata agccaacttt gccagttcag catttttctc
     8821 acgaacaact acaaatttcc aaggctggct gttgtgggcg cttggcgcca aggttgcaat
     8881 ttcgatagcc gtacgcacat cttttggatc aacaggctta tcagtgaaat gcttggtcgc
     8941 atgacgtttt ttatttaatt caagaaattt cataatcgat ttccttttct aattctactg
     9001 cttccattct accataattt gaaagagctt gcagggattt ttcatgatta agtttttcta
     9061 tcacagacat aaaagatata tattggttta tcaggaaagt ttctgataaa ctagcaagta
     9121 ctttacattt gaatggagac agtatgaaaa aatttagcct attactagct atcctaccat
     9181 ttttggttgc ctgtgggaat caagctacac ccaaagagac tagcgctcaa aagacaatcg
     9241 tccttgctac agctggcgac gtgccaccat ttgactacga agataaaggc aatctgacag
     9301 gcttcgatat cgaagttcta aaggcagtag atgaaaaact cagcgactac gagattcaat
     9361 ttcaaagaac cgcctgggaa agtatcttcc caggacttga ttctggtcac tatcaggctg
     9421 cggccaataa tttgagttac acaaaagagc gtgctgaaaa atacctttac tcgcttccga
     9481 tttccaacaa tcccctcgtc cttgtcagca acaagaaaaa tcctttgact tctcttgacc
     9541 agatcgctgg taaaacaaca caagaggata ccggaacttc taacgctcaa ttcatcaata
     9601 actggaatca gaaacacact gataatcccg ctacaattaa tttttctggt gaggatattg
     9661 gtaaacgaat cctagacctt gctaacggag agtttgattt cctagttttt gacaaggtat
     9721 ccgttcaaaa gattatcaag gaccgtggtt tagacctctc agtcgttgat ttaccttctg
     9781 cagatagccc cagcaattat atcattttct caagcgacca aaaagagttt aaagagcaat
     9841 ttgataaagc gctcaaagaa ctctatcaag acggaaccct tgaaaaactc agcaatacct
     9901 atctaggtgg ttcttacctc ccagatcaat ctcagttaca ataacactct tcgaaaatct
     9961 cttcaaacca cgtcagcttt atctgcaacc tcaaagctgt gctttgagca acctacggct
    10021 agcttcctag tttgctcttt gattttcata ttgagtataa gatatattaa aagcgatggg
    10081 atcagccaat cgctttttta gtttgcattg gttattttag gaaactctta caaaaaatca
    10141 aaaaaattct tcacatcctc tacataccta tgcttttcta ttaagcttgc taatagttcc
    10201 agattgtgcc tctgatagtt atcttcacga cgtagttctt catacatttc gataaaggga
    10261 aaacccttgg atttggcaaa ttctaactca gcctcgtaat cataagcgac tttacgaaat
    10321 aggatattta ccaattcccc atcttcaacc tctatcacgg catactgggc acggtgattt
    10381 tttaacgcct cccaattaaa atagggcatg ccaatcgacc ctggattgat gatttgttgc
    10441 ccttgactac cataacgaag caactacttg tgaacatgac cataaactgc cacgtccgtt
    10501 tccgcatcta gcagttggtc aaatttctct gtatcattct caactagcaa gtcaccacca
    10561 tagtttttgt caggtaaatt atgagagata gaaaagcgca atccgtcaat ttctttcttt
    10621 tccagcaaag gcaagcttcg tagccagaca atcgttgcag gatccattcg ctccatcaaa
    10681 tactgtgtca tacgcaagag ctgaacttcc tgtgggtctt ctaagccata ttgcccatct
    10741 aaagcctcaa ggacacaatc atcccaattg cctcgaacac ttgccgtgat aggaagttcc
    10801 tttaacagag cgaccaagtc atttgcacct ggaccaggga ggaaaatgtc tcccatgagc
    10861 caatattcac tggctccttg agttttagca tctgcaatca ctgcttctag cgccgtcgca
    10921 ttgccatgaa catctgataa aattgcgatt ttatggttta ttgtggtttc cttccgtttg
    10981 gtaatctact ctttcttccg ccacttgaag caagatttct gtttcctgcg ggttcaactt
    11041 ggtttgcaca gcctctgcta ctgctcttgg tactccaact tcgacaatct catccacact
    11101 ggcttccttg attttggtca gagacttgaa gtgcctcatg agattttgct tgcgtttagg
    11161 tcccagacca tcaatcccat ccaattgaga tgagaaagaa tttttggagc gcagttggcg
    11221 gtggaaggta atggcaaagc ggtggacctc atcttgaatg cgttggagga ggaaaaattc
    11281 ctgagaattg cgagacaagt ccaccacttc cagcggatct ccaaagagca attcatgggt
    11341 ttggtgctta tcattctttt gcagacctgc aattggaata tccaagccca gttcttcttg
    11401 gatgacttgc ttagcaatat tgacttgacc ttgcccccca tcaatcacaa tcaaatctgg
    11461 aggagtcaaa gcctcacgct gtactcgacc atagcgtctg cgaatgacct ctcgcatact
    11521 ggcatagtcg tctggcccga ctacggtctt gattttatac ttacggtaat cttttttact
    11581 tggcctgccg ttaacaaaga ccaccatggc tgaaacagga ctggtcccca tgatgttgga
    11641 gttatcgaag gactcgatgc gaactggagt cggaatttgg agcaaacgtc ctagattttc
    11701 aatagctcct tgggtctttt cgactgattt ttctagcagg ttaaatttct gctccagact
    11761 aacacgtgca ttttttatgg ctagattgac cagctgtttt ttctctccac gttggggttt
    11821 gagaatcttg gtatccacca aagccttgac agcttcttcg tcaatatcct gcggaatcag
    11881 tacctcattg ggaactaggt gagatttttc ttgatagaat tgtcccacat aggtcaagaa
    11941 atcctcatct ggatcattga agtaggggaa gagattgaca tcgcgctcga tgagcttgcc
    12001 ctgacgaaca aagaaaacct gcacacacat ccagccctta tccacatagt agccaaagac
    12061 atcgcgattt tggagatcct tagccatgac ccgttgcttg gttcgaagcg ttccaatagc
    12121 ctgaatcagg tcacggtatt ccgccgcacg ttcaaactcc atagtctggg ctgccgctgc
    12181 cattttgccc tttagctcat caatgatttt gttatcctgc cctttcagaa aatcagaaac
    12241 ctcctgggcc atagacttga aataagcctc atccttctta cagatggtgt gagccataca
    12301 ctggccgata tggtaataaa aacagacctt agagggcggg ttggtacact tacgaaaagg
    12361 gaatatccga tccagcaacc gcttgatttc attggctgcc cccacatcgg gatagggtcc
    12421 aaaataaaga cctccgtcct ttttgacctg acgagtgata atcaagcgtg gatagcgctc
    12481 attggtgatt ttgatgaaag gataggactt gtcatccttg agcatgatat tgtacttggg
    12541 cttgttttcc ttgatcaggt tgatttctag gagaagtgcc tcaatattag actccgtaac
    12601 aataaattca aaatccacaa tttcagacac cagagcctct gtcttggtat catgacttcc
    12661 acgaaaatag gaccgtactc gattacgcag atttttagcc tttcctacat agataatgga
    12721 gccattttta tccttatgaa tgtagcaacc agggctggtc ggcaagagct ctagttttga
    12781 tttaatcaag ttgttcatag ttccattata gcaaaaaaag tagggaaaga tagtacccta
    12841 ctcactagtc tcatatattt ttcggaggtt tgcaacatcc tcttcctgga taccataaaa
    12901 ggaacctgct ggttgcatga cagacttctc atctgtatgg tccaagccaa tcgcatgacc
    12961 taactcatgt tctgccgtat ggacaaggcg ttcataggag tagccatagt gtggattgga
    13021 caaataataa tgattcaacc gcaccgttac ggacaagaat tgccctgcta agagattagt
    13081 ttgactttcc gcctctcctg ccacaggagt gcctccgtcg ttcatctccg tagccgtaat
    13141 atccgcctta ctagactcag tcacgagttc aaagttaaaa gcaccagttt gattccagtt
    13201 ctggattgct tctaaataag cctcttgaaa gcgtgaatcc atctgcggat ccaggtaaat
    13261 acgagcagag gcctgtgccc accttccttc agaatgctgg tgactatctg tctggcttaa
    13321 cttaggcagt tgccctgttt tctcccattg gtcaatactt tgttgaccaa tttttactga
    13381 ccgttctgct tgctttagcg ctccttgaaa atccccgttc agataccaga gaagtccgaa
    13441 agcaagcaca cataagagca caactatcca aaccagacgc caaaacaaac gccacacaaa
    13501 agaaaagaaa gcccctatca aacgaaaaag ccagcgcatg tctctccacc tttctagcaa
    13561 ataagaatta ttttactaaa agaagctaaa agaaatctaa atactgactt tttcatctta
    13621 acgtcctact atttttttga gtaactggat agctttgtat tttaaaggcg atggatggta
    13681 acggaaagta cccgctttgc gtacaatata gccattaaaa ttctgtttaa aacgcaaaac
    13741 accatcactt ccatcaaaaa tcccttgaat gcctaggaaa ttgtatttag gtattccacg
    13801 ttttatgctt tccaacataa catatttttg aagcagtgca ggggcataga acttattaaa
    13861 ctcagtgtag gaaccactaa agagataagt cgtttcctga ggcatataaa caaataaact
    13921 cccagctaaa acaatatctt cttctccata tttttcaatc aagtctcgcg cttctgcttt
    13981 tcgaacttca aacgtttcaa attgactaga atattctctc agttgatttt gttttttctc
    14041 agaatgagga tttttactca aatcaagtcg caacttgtcc aagttttctt ctagtttact
    14101 ttgttcacct tgcaatttgc tcatatactc cgaaaaattc aagcttgcta tgagaaactc
    14161 cgcttgttct ccaaaagtat cataaaaata ctcataatat tctaaacttt tatcactata
    14221 ttctctacgt tcagaggttt cttttgttat attcttaaaa atcgatagtt cttcacgttt
    14281 taactttttc aaccgaatgc caaaggtttc agcctttttc accaagggtt tacccttttt
    14341 gctaaaactt ttaagcaaac tcttttcagt taattcagtt aaatctttat agtataacca
    14401 atctggttct ccacctgggt aacctgttgt taagccatca aattgataac ctaaatcagt
    14461 caaaccttga ataatacttt ttttctcagc atctattgga ttaccttggc tatcaaaagt
    14521 ttgataagtt tcataaggtt ttacaagcaa ctctaataca ccattttgct tggcatattc
    14581 ttttaactct gcataaaaaa ctggaagagc atcttgttgg gtataaatcg gccccgaatt
    14641 gagttccata tgcagaccac ccagcatggg caggctataa accagagctg caacttgaat
    14701 ttctccttct tgtttcaaag caagataaac aattcgagcc cctctttttt ctagcaaatc
    14761 ccccatctgg acagattgca taaaggaacg agaagaaacc tgatcagaat aagtctgaaa
    14821 ctcttctttc gtgagtgttg ttagtgccat atacttactt tctatgtttt tttcttaatg
    14881 ttttacggaa atcaagagca agtcttaaca gaggatagag aggatgagtg ggcattgtaa
    14941 attcacccaa gtattcttca atcgttggat taaatttttc cttaaaatga taaagtccac
    15001 cattgagaga gttttcaaca ccacctaaat tttgccagac catacctcgc tcaaaggcat
    15061 agcgagccgt ttcataccat gttaaaattg gtgcattgta acgtttaaaa tcatcatcca
    15121 taccagcata tatattgaca gaggtagtac caaattccaa actcaaagta gccgctaaag
    15181 gaactctcgc ttgacctaca tctatatatt cctgcaagaa ggtcaattcc tctaacaaac
    15241 gttctttttc cttcttctgc gcttctactt ttgaagttcg agtcgactca gtaaacgtct
    15301 cttccaaggc tctatttttc gctaactgtt cttctaactc ttgcgaacgt ttagaaacat
    15361 ccaaggtggc caaggtgata taggccttgt ccttaaaatt atctaacaat tttttataat
    15421 aggcttcatt cctcaaatga atctcttttc gcttctcagt ttttttcatc aactccgaaa
    15481 atgaatctaa tagttccagt ccaccatatt gaatctcaag ccctttgttt cgtgctgttc
    15541 gaatagcctg ttttgttgac ttggaaagtt tatcttcttc aaaattttcc ttgtatattt
    15601 tcgcctgaat acgaggttga atggtgtctc ccatttcctc cgtttttcct gaccacctta
    15661 ctcccatttg ttgcaaacta tcaataatag ccagattttc aggaaattct gtcttttcct
    15721 gattgattaa actttgagat aggcaaatac ttgggtcaaa agtcacaaaa accgctctct
    15781 tactgcgagc ataggactta atagactgaa tgacaaaatt caagagttct ttatccccat
    15841 aatccaatat aggtcctctt gggatgtaaa acattttata gcctagcgga agagttctaa
    15901 tcaaaatact agctgtcgcc agtaattttt cttccctgta aacaccaaac ttctcatgtt
    15961 gccaattaga cttaacttcc tcccaagcac tactttgtaa tacattggct aattcatgtt
    16021 ctttgacaaa ctgatcatat tctaatgtgg gaatgccaat ttgataacgg tacatttcct
    16081 actctctttc ctccagtatt ttattactat tctactactt tcgtttgaaa agtctagtga
    16141 aaacatattt tattttagtt ctactccccc tatgctgaag ttcaaactaa gtcagtctct
    16201 cttctaattt gaaatcaatt ggtagggttg ttaaaaaaac ttccaattgt ttttcccagt
    16261 agtaccactc gtgagttcca gcgctatggc tataggtcac atcaaaacct agttttttga
    16321 gatttttcac tgcgagatta ttggcttcgt acaagaaatc ctgttcgcca caccacgccc
    16381 aaagtttggt ctttttatcc gattttttag ccagactttc aagagaatag ggactagttg
    16441 tccagtcttt aatctctcca aaaacacctc tccagtaggc tggacttccc agattttgac
    16501 tttcaggaga aaagttttga aagctgaggg cacctgaaaa gctagctgca tgagaaaaac
    16561 gatttgtcgc aagagccagt ttgaagcagc cgtagcctcc catagaaaga ccagcgataa
    16621 aggtcttttc acgcttgcta gtcatattag ggaagaagcg tttcagaacc tgtggcaatt
    16681 cctctgctag agccgtgtag tagtcaaaac catactgggt atcggtgtac caaccattgc
    16741 tggtattggg cataacaacg atgagattag ttcctcgaag caagcgttct acattggtcc
    16801 gcttaagcca actattatga tttccagaca tcccgtgcaa aaggtacaag acgggaatat
    16861 cttcacactc tggttcttcc actcgattgg catcagggta gaggacattc accccccact
    16921 ccatatccaa tacttgtgag taatactcga ttttcattac tgccatgatt ttctccttct
    16981 atttttctat aagaaaaagc cgaaactcga ctttctctct gtttatttca acgattattt
    17041 tgcttccatg actactggta aaatagctgg acgacgcttg gtttggtcaa agagatactt
    17101 ggtcaaatta tctcgaacct tccctttaag atctgcccag tcaaagtcat ctccttgaag
    17161 atactcttct accgtttggt taatcaattc tgaactttca cggagaatat cgcgactctt
    17221 cttgagataa acaaatccgc gcgtatgaac acgagcccta gccacaattt tcttctcacg
    17281 acggttgact gtaatagcca cgatgaaaat tccatcctct gacaagacct tacggtcacg
    17341 aagaacaaca tttccaacat caccaatggc attcccatca atcaagatat ctcctgctga
    17401 aaccgatcca gctggaacaa agtctccatt ctcgtaagcc atggtcgtcc cctttttagg
    17461 aatgaagatg tgttctggca acatcccaac tgccatggca gccttagcgt gagcatccaa
    17521 ctcacgatac tccccttgga cagggaagag gtacttaggt tgcaaaagat tgatcatcag
    17581 ctgcaaatca cgcacatttc cgtgccctga tacatgtaaa ctttgggtaa tcaatttgac
    17641 aaccccacct gcctgataaa tcatattttc cacacgcgca acaaaggctt ctttagcaat
    17701 agacggagcc gtagcaatat agaccaggtc cccatccttg atttctacat aacgatggcg
    17761 accaatcgac atcttacgaa gtccattgat aggttcaccc atacgacctg tctcaagaat
    17821 aatcaactca tggtcttcaa agcgagacat atctttaggc ttaatcaaga gaatttcgtt
    17881 ggctaaagac aacttcttaa gacgaatcgc tgtgcggacg atattttcaa tatcaaatcc
    17941 tgtcaagacg atacgtcgac ctgttttatc cgcagcgtca aaaatctgct gaatacgaga
    18001 aagattactg gaaacagctg caacgatgat acgaccttcc cagtcagcaa tagtttgggt
    18061 aatttcatcc ctaacttcac tttcactagc cacctgaata ttgctgtctg cattggccga
    18121 atcactgagg agagccagga cgccgtcacg accaatctct gccaaacgag caaaatcagt
    18181 tgcataagat tcactagccg tttggtcaaa tttgaagtca cctgtataaa cgatgcttcc
    18241 ttccgatgtc ttcaagacaa ttcccagact ctctggaacg gagtaagtcg tagggaagaa
    18301 ggaaaccact gtcccaccaa aatcaatctc cgtattctca tcaatgacat ggaaatcatt
    18361 aaatttctta acggcatcat ttcctttgac aaagagcttt gccaactcaa tggtcaactc
    18421 agacccaaat acaggaactt tagcctctgc caagagataa ggtagagcac caatggcatc
    18481 cgcatgcccg tgggtcaaga aaaccccagc aatacggtcg ctattttcaa aaaggtaatc
    18541 catgtttgga atcaccacat cgacccctaa ttgttcattt tcaggatatt ttaaccctac
    18601 attcaaaaca aaaatggact ctccaatttc agcaatgtac atattttttc cattctcacg
    18661 cacaccacca agtgttgtta aactgatatt actcattttt cctccaaaat cttagtttat
    18721 cttgattata gggcaactct accctcttat tctaaaagtt ctaatacttt cagccgaatc
    18781 ttttcctacc attataccat ttttttgatg attttcaaaa tgaaggtctg ttttcaaaaa
    18841 agagttgatt tcccaactct ttcctaactt ctactctttt tccatcaaaa aatcataaat
    18901 ttcttgcacc gtacccagcg ccatcatttc ttggtcttta acggtttgtt tgagattttg
    18961 gtaaatttga ctttctccta tctcccgctt tggcgcctct ttattgactg tcatcacacc
    19021 atcttttatc gtcacaaagc ctagttcttc aaatacttga atcatcttga ccagcaagat
    19081 ttgttgaata ttaagatatg cagccaaatc tttcagcttg tagcgaatat caaactctgg
    19141 gaactggtaa atagtcttgt acaatttggc aaactgatct ctagtcccat aacctgtcag
    19201 ataataggcc ttgtcaatat catttttgaa atagacagca gagaaatgct gttcctgaaa
    19261 aatggtcttc agctgagtaa tatcctctgg aatgtttttt acgacaatag cttcactagc
    19321 cgcaagattt ggcagttctc caggaaaatc caagactgga acaccttctg gcaagactgc
    19381 attttttcca cgaatgttaa aaagttgaac accttccact cgcgcatcca ccatcatcaa
    19441 ctggagggca gtttggccat tccattggtt gacagacaat ttaaccgcta actctagatt
    19501 cttggtttga gaaaactctg tcgcccatct gccttgacca aaggctacca cttcaaaact
    19561 cgccccaccc ttggaaattt tcagctttag atgggcatta cctgccccca tagtacgagc
    19621 actttcgacc tgaaaattct tgatataaaa aataggtttc tgattatcca ttccaaaagg
    19681 agctaaacgt tcaaaacttt tgaccgtttc caagctaagt gcctccaaat ccaactcttc
    19741 atctaggttt aacttattct tgccaccagc atctgcacct ttttcacgaa cataatcttc
    19801 caaaacctga gataaatctg agagttgctc aacttccagc gtcatacccg ctgcacctgc
    19861 atgacctcca aaggcgatga agaggtctcg atggggatcc agagcttcaa aaatatcgac
    19921 cgcttccaca ctacgagcac tgcccttggc acgaccgtct tctatattaa gaacaatgac
    19981 tgtctgtccc aattcttcca ataaacgacc agccacgatt cctagaaccc caggattcca
    20041 gccttccttg gccaagacct gaaccttctt ctcaggatcc accatggtct tggcttcttc
    20101 atagatagac tgaacgattt ccttgcgctc ttcgtttttc tggtgaatca taagggcaat
    20161 ctcatgcgct tcctcatcat caaatccagt caacaaatca atggcaggat tgggatcatc
    20221 caagcgaccc aaggcattca aacgaggagc aatctggaaa ccaaccgttt cttctgttac
    20281 ttcgttggca gcaatcccag ccatgtccag catttcttgc agaccaatgc gctgggtatg
    20341 acccaacatt tccagaccat attgaactaa gatacgattt tcatccgtca gactcaccat
    20401 atctgcaata gttccaatag cgaccaaatc aagcaattcc acttgcactt cttctaacag
    20461 ggcacaagcc aacttgaaag caactccaca accagccaaa tatttaaaag gataatccgc
    20521 atctggatgt tcaggatgga caatagcata agcatctggc agggtttcag gcatggaatg
    20581 atggtctgtc acaatgacat ctactcccat agactgagcc aatgcaatag cctcatgacc
    20641 agcaacccca ttgtccaccg tcacaatcaa ggaaattcct tcttgctcga taaagtattt
    20701 ataaacacta gcattagggc catagccatc ggtaaaacga tttggcaggt aaactcggca
    20761 ctccgcacca agttgttcca aactttcctt cacaatagaa gccgaagtca tgccatccgc
    20821 atcgtagtct ccataaacga gaatattttc cctttcttca atagcctgac gaatccgctc
    20881 cactgccttg tccatatcat ggagcagata agcatcatgt aagtcctcca aggaaggttc
    20941 taaaaacttc ttcagacttt cttggtcctg aatccctctc tcaaacaata accgagccac
    21001 ctcaggaccc agtccagcct tcttggctat ctttgtaaaa tccgcatctt ctacctgcag
    21061 ggcaaactgc cattcataag taggtgttat caaaaagaca tccactcctt ctaagaattc
    21121 tattgcttca ttataacatg atttagacgt tttctctatc cagattgctt ttttataaca
    21181 tttcatagta tattgaaact agaatagtac acctctactt ctaaaatatt gttagaaatc
    21241 gatttgactg tcccgatcga tttttcctgt tcttatttca ctatagtgaa ttttttcaga
    21301 tatggtttga caagaacatt cttttattgc agaattgtgt tataaaatct aacataaagg
    21361 agttctctca tggctttagt agaatttaaa aacgtcgaaa aatattacgg agactaccac
    21421 gcactccgca acatcaatct ccgttttgaa aaaggacaag ttgttgtcct gcttggacct
    21481 tctggctctg ggaagtccac tcttatccgt acgatcaatg gtttagaggc tgttgacaaa
    21541 ggaagtctcc tagtcaatgg gcaccaagtt gctggtgcca gccagaaaga tttggtacct
    21601 cttcgcaagg aagtcggcat ggtttttcaa cattttaacc tttatccaca caaaacagtg
    21661 ttagaaaacg tgacacttgc acccattaaa gttctaggaa ttgataaaaa agaagctgaa
    21721 aaaaccgcca aaaaatatct ggaatttgta aatatgtggg acaagaaaga ttcctatccc
    21781 gccatgctat ctggtggaca aaaacagcgg atcgccatcg ctcgtggtct tgctatgcat
    21841 ccggaactcc tcctctttga tgaaccaaca tctgctcttg atcctgagac tatcggagat
    21901 gttctagcag ttatgcagaa actggcgcgt gatgggatga acatgatcat cgttacccac
    21961 gaaatgggct ttgctcgaga ggttgcggac cgcattatct ttatggccga cggagaagtt
    22021 ttagtagata cgacagatgt cgataacttt tttgacaatc caagcgaacc tcgtgcccaa
    22081 caattcctca gcaaaattat caaccacgaa agtgacaaag tcaaataagg aggcgcctat
    22141 gaaaaaaaat tctttttatc agcattattg attagccttt tcggccttgc tgctgccaaa
    22201 ccagtccagg ctgatacaag tatcgcagac attcaaaaaa gaggcgaact ggttgtcggt
    22261 gtcaaacaag acgttcccaa ttttggttac aaagatccca agaccggtac ttattctggt
    22321 atcgaaaccg acttggccaa gatggtagct gatgaactca aggtcaagat tcgctatgtg
    22381 ccggttacag cacaaacccg cggccccctc ctagacaatg aacagggcga tatggatatc
    22441 gcgaccttta ccatcacgga cgaacgcaaa aaactctaca actttaccag tccctactac
    22501 acagacgctt ctggattttt ggtcaataaa tctgccaaaa tcaaaaagat tgaggaccta
    22561 aacggcaaaa ccatcggagt cgcccaaggt tctatcaccc aacgcctgat tactgaactg
    22621 ggtaaaaaga aaggtctgaa gtttaaattc gtcgaacttg gttcctaccc agaattgatt
    22681 acttcccttc acgctcatcg tatcgatgcc ttttccgttg accgctctat tctatctggc
    22741 tacactagta aacggacagc actactagat gatagtttca agccatctga ctacggtatt
    22801 gttaccaaga aatcaaatac agagttcaac gactatcttg ataacttggt tactaaatgg
    22861 agcaaggatg gtagtttgca gaaactttat gatcgttaca agctcaaacc atctagccat
    22921 actgcagatt aaggaggaca ccccatgaca gatttatcat cttggacagc ctattttcag
    22981 gattttggac aatttttcaa tggtttcctc ttcacccttg ccctagcgat tggatccttt
    23041 atcctcgcca tggtcttagg aatcttcttt ggtgccatgt caaccagtaa acgtccaatt
    23101 ttacgcattt tagctcgcat ctttgtggaa ttttaccaaa acactcccct cttggtgcag
    23161 tttgttattg ttttttatgg cctacctctt atcagtgacc atactatcat gattccgatt
    23221 tattggacag ctgttctctg cgtgggactc tatcacggcg cttatatcgc tgaggttatt
    23281 cgttcaggga ttcagtctat tcctagtggt cagatggagg ccgccttatc gcaaggtttt
    23341 acctatatca gtgccatgcg cttgattatc ttgcctcaga ccttccgcat cattctccct
    23401 ccattgacca accaaattgt taacctcatc aagaacacct ctactgtagc tatcatctct
    23461 ggagtagact tgatgtttgt gactaagtct tggtcggctc tcaacggaaa ctatatccca
    23521 gcctttttag gtgctgctct tctctacttt gccctatgct tccctgttgc ccagtttggt
    23581 cgcaagatgg agcaagccaa caaaaaagcc tattcacttt aggaggttac tatggaatct
    23641 attttagaag ttttaacccc agataaccta gtctttatct ttaaaggatt tggcttgacc
    23701 ctctatattt ctctgattgc catcatcctc tctactatca tcggtacggt gctagctgtc
    23761 atgagaaatg gcaaaaattc tgtcttgcga atcatctcca gtatttatat cgagtttgtg
    23821 cgcaacgttc ccaaccttct ctggattttt actatctttt tggtgttcaa aatgaaatcc
    23881 acaccagcag gtattacagc ctttactctc tttacatcag cagccttggc tgagattatt
    23941 cgaggcggtc tcaatgccgt agacaaggga caatacgaag caggaatgtc acaaggcttc
    24001 acctcagccc aaatcctcta ctacatcatt ctcccacaag ccatccgcaa aatgctacca
    24061 gccatcattt ctcagtttgt taccgtgatt aaggatacca gtctcctcta ctctgttatc
    24121 gccctacaag aactctttgg agccagccaa attctcatgg gccgttattt cgaaccagag
    24181 caggtcttca gtctttacat cctgattgcc ctcatctact tcagctttaa cctagcaatt
    24241 tctagcctgt ctcatatgct agccaaacgt tggcaacaag ccgcagaata atactcttcg
    24301 aaaatctctt caaaccacgt cagcttcacc ttgccgtata tatgttactg acttcgtcag
    24361 ttctatccac aacctcaaaa cggtgttttg agcagcctgc gggctagctt cctagtttgc
    24421 tctttgattt tcattgagta taaacagcca ctctccaatt caattggaga gttttttgat
    24481 gagagtagat atttatagac ctcaatttga caccatacat tttctatgat aaaatgtaac
    24541 aaattcattt acaacaaatc gaaatctaaa tgaaatggaa ttttctatga aatcagtcaa
    24601 aggactactc tttatcatag ctagttttat cttgactctt ttgacttgga tgaacacttc
    24661 tccccaattc atgattccag gactagcttt aacaagccta tctctgactt ttatcctagc
    24721 cactcgtctc ccactactag aaagctggtt tcacggtttg gagaaggtct acaccgtcca
    24781 caaattcaca gcctttctct ccatcatcct actaatcttt cataacttta gtatgggcgg
    24841 tttgtggggc tctcgcttag ctgctcagtt tggcaatctt gccatctata tctttgccag
    24901 catcatcctt gtcgcctatt taggcaaata catccaatac gaagcttggc gatggattca
    24961 ccgcttggtt tacctagcct atattttagg actctttcac atctacatga taatgggcaa
    25021 tcgtctcctt acatttaatc ttctaagttt tcttgttggt agctatgccc ttttaggctt
    25081 actagctggt ttttatatca tttttctata tcaaaagatt tccttcccct atctagggaa
    25141 aattacccat ctcaaacgct taaatcacga tactagagaa attcaaatcc atcttagcag
    25201 acctttcaac tatcaatcag gacaatttgc ctttctaaag attttccaag aaggctttga
    25261 aagtgctccg catccctttt ctatctcagg aggtcatggt caaactcttt actttactgt
    25321 taaaaattca ggcgaccata ccaataatat ctatgataat cttcaagccg gcagcaaagt
    25381 aaccctagac agagcttacg gacacatgat catagaagaa ggacgagaaa atcaggtttg
    25441 gattgctgga ggtattggga tcaccccctt catctcttac atccgtgaac atcctatttt
    25501 agataaacag gttcacttct actatagctt ccgtggagat gaaaatgcag tctacctaga
    25561 tttactccgt aactatgctc agaaaaatcc taattttgaa ctccatctaa tcgacagtac
    25621 gaaagacggc tatcttaatt ttgaacaaaa agaagtgccc gaacatgcaa ccgtctatat
    25681 gtgtggtcct atttctatga tgaaggcact tgccaaacag attaagaaac aaaatccaaa
    25741 aacagagctt atttacgaag gattcaagtt caaataagta atcatactct cctgggattt
    25801 cccaggagag ttttttatag ccaaatgaaa taagaccgga acgatggaat tttggcattc
    25861 aaatcaattg ataagaatat tttatagtgg agtgaaatag gatacgaaca aattgattag
    25921 gaaaatcaaa tgaatttata gaaatctttt agcagttatg ttgtcctatt ctagtttcaa
    25981 aacgctatag aagcagcatt gtactagtct agattcagtt tactatacta aaacgagtag
    26041 cttgaaatca aaaaacccac cctcacaggc aggttttatc tgtattattc agctagatta
    26101 tgctttacct tctgaaccga atacgtcgat acgttcttca accgatgctt ggatagcttt
    26161 tacaccgtca gccaagaatt tacgtgggtc gaagagtttt ttcttgtcgt attctgcttc
    26221 gtttgcttcg tagtcacgag caaatttacg agttgcgtta gcgaatgcga tttggcattc
    26281 tgtgttaacg ttaactttgg caacaccaag tttgatagct gcttggattt gctcatcagg
    26341 aatacctgat ccaccgtgca atacgattgg gaatcctgga agagcttctg tcaatttttg
    26401 caagtggtca aggtcaagac cttcccagtt tactgggtaa gggccgtgga tgttaccgat
    26461 accagctgcc aagaagtcga taccagtttc aaccattgct ttagcgtctt cgattggagc
    26521 caattcacct ttaccgatga ttccgtcttc ttcaccaccg atagtaccaa cttcagcttc
    26581 tactgagata cctttagcgt gtgctttttc aacaacttct ttagccaatt taaggttttc
    26641 ttcaactgga aggtgtgaac cgtcaaacat gattgaagta taaccaactt cgatacactc
    26701 aagtgcatct tcgtagtgac cgtggtcaag gtggatagct actggtacag tgatacccat
    26761 tgattcaaca aggttagcga tcaagttgcg agcaactttg taaccaccca tgtatttagc
    26821 agcacccatt gaagtttgga tcaaaactgg agctttttta gcttctgctg cgcgcaagat
    26881 agcttgagtc cactcaaggt tgtttgtgtt aaatccacca actgcataac cgttgtcacg
    26941 ggctgcttgg acaaattttt ctgctgaaac gattgccatt ttatcaggcc tcctgtatat
    27001 ttttatgggt catcccattt acattgttca ttttatcact ttttgccaaa aaaatctagt
    27061 ttttcccgca gtttcgattg attttcttct aactccatct atgtaaaccc tttctctccc
    27121 tagtcttggg cgacttttgg aaaagctata aagaaggtta aacgattctc ctccatctcg
    27181 aaacgataag ctaatttttc atgttctaat agactcttaa ccacaaagag ccccatacca
    27241 gaccccttga ccttgcgact ggcattgtca gaaaaagact gggctagttt ttcttgttcc
    27301 tctgagctac agctattttc gataaaaagt tctccttctc tttctccaat tcgaactaag
    27361 ccacctggaa cagagtgctt aatggcattg ctgatgagat tagaaagaat caacttcata
    27421 actgatgggt ttagataagc ctgctgatgg gtcaaactat tgtctatctg gagctctctt
    27481 tccttggcta gcaaggcata atctttgacc agattttgcg tcatctggag gaggtcaatt
    27541 gtttccctat catctcgcaa ttcctgcaca gaagagaggg aaagtatctg cagaacatgg
    27601 tgattgagtt catccacaat ccccaaggca actcccagat actggtctct atccttataa
    27661 cgaccgatat tctctctcat attttcgatt aggattttca aactagccag cggtgttttc
    27721 aattcatgag aagctcctcg taggaattcg accttcatct tctccagctg gagaatggct
    27781 tcattctttt catgcaagtc cgcaataaca gtcaagagat gctggtagag gctattgatt
    27841 tgttccttga gattacctat ctcatcctta gaatccacgc gcaatcgcac ttgggaatcc
    27901 aggtccatca tccgacgggt cacccgcttg atttccaaaa tcggtgcaac aatagtccgg
    27961 gcgtagatgt aggccaccaa gagggaaatc agaaaggagg ccagcaaggt atagggaaga
    28021 aactggagac tgatttgctc cgcttccttt tgtaaatcca tggaagctag aaactggaga
    28081 atcatagtac caccgtcttg cgttttcacc tcgcgctcct caataaagag agaggttgtc
    28141 tggcggtctg tgtccagagg aagactgtcc ttgacttcta acttgtcctc ggtcatctca
    28201 cctttgacgg tccccttgat atcactagtc tgggaataca agtctaacac ttgctcgata
    28261 ctctgcctat ctttcccttc tagggactgg gcaatggctg ttgccttttg accaatggtt
    28321 tcctgacgat gactcagata agtcgaagga aaaagaaaat aaatagctaa atgaaggcag
    28381 ataaccagaa cactaaatat cgagaaggta tagataaata tctttgcaaa taaacctgtt
    28441 cgtttcattt tcgctccaat ttataaccaa cattgcgcac agtgaggata caatccaagt
    28501 ctagcttttt ccgcaattcc ttgatataaa catcaataac acggtcaaag ggaacctcat
    28561 ctgtcgcttt ccagacggca tcgataatct gagaccgagt caaggcccgg ccttcatttt
    28621 tcactagata gtccagaatt tccaactctt tggcattgat aggcacttct tgacctgcga
    28681 ggcttgcact gtagctttca aagtccacct tggtatcctt gtaagaaaag attcgtcctg
    28741 tatcgtagta gcgcttgaaa atcgcgtcca ccctcacttt taagagggag agagagaaag
    28801 gtttttccag atagccatct gccaaagagg caaaggcact catcttgtat tcctcatcct
    28861 gaaaagctgt caacatcaag acaggaacct gactggtttt acgaatctca gctaggactt
    28921 ctaagccgtt aagcttgggc atctggatat ccagtaaaac cagggccacc tcatagctag
    28981 aaaattgctc cagagcttcc tgaccgtccg ctgcctcaat agtttcatag ccacaatccg
    29041 tcaaataatc actgaccccc tcacggatca tctcttcatc ttctacaatt aaaattttca
    29101 tactttaact gctctctatt ttttattttt cttagaataa atacctactc tattttctat
    29161 tatagtctct tgctggcctt ttgtctgtaa gcaactgatc actagataaa acgttgtgaa
    29221 attcctttct cataaattcc ataactttag tatattatat ttaagcacta aagtacaaag
    29281 aaagcaactg aaagcaatga ttttcaccac tgctttcaga tttattttga attgttaaat
    29341 agctattcct atccactatt cttgaataga aacacaagat gcaatcttta ttccagactc
    29401 attttttcaa atttattcac catccagcaa gagctctttt ggttgttttc taaggagatt
    29461 gcttgaagca agcgccataa cgagaaccac tagaaccaag gcaaggacaa aaatgatgat
    29521 aaagtctgat gtctgaatgg aaatgtctag gctcgacaag gtcttgctaa agccatctac
    29581 ttctgcaccg ccaccaaggt tagaggcttg agccgcctta ctagcctgtt tggcaacacc
    29641 tgaagtcaca ttggcaagga cagtgtttcc aattgcacgg gcagtgtaat tagctaggaa
    29701 gtaagcagaa actagagcag ggatagcaat caagatagat tcggtgatga attgacccaa
    29761 gatacttgcc tgcttgaggc cgatagagag gagaattccc acttccttgc gacgggcgtt
    29821 gatccaaagg ctgagcaaga gggcaaggag gagaactgag aagctcaagc taccccagaa
    29881 gaggaggttg gccatcttgt acataccaga gatagattgc tcaagagctg ggtagttaga
    29941 ggagctcttg acgagtgtgt agctcttcca gttgatacca ctgatgccat tcaactcttt
    30001 cataacatca tccaagttct tgtctgctgt tacaaagaag gttgcgtccc cataaatggc
    30061 tgtgtcttct gtgtatccat aaagttttgc agcagtgtga atgtctgtaa tagctgtgtt
    30121 ttcgtaaagt tcttgtgagt aggttactgc tgacttatta tgaccatcaa agagtccctt
    30181 gattgtcact tcaactgttt ccttggctcc tttttcatta tctgcatcgt agatattaga
    30241 gtccagttta accttgtccc ctactttcca gccgtgtttg gctgccaagt ccttgtgcaa
    30301 gaggatttta tccttgtcgt cgttggttaa gtgctctcct tcgactagtt tataagaacc
    30361 agagacaaac ttgtcttctt tagaggagtc attgacacct gtaatcatca agctacttcc
    30421 aaaacgtttg gcacgatcag cagtgagatt cttcttggtt tctggcgttt caatcaggtc
    30481 atatccagtc aaatctccga tagcgttgat acgtttgaca taagactcaa tggccttgtt
    30541 ttcggtgatt tttttgatgt cttcaccctt gatattccca gcaccgcgag gcgttccttg
    30601 gttgacgcga cgattgattt gcatggagaa gctattggtg atatttttaa aggtctcctg
    30661 agaagccttg gcagtagctc ccttgattga caagccgacc aaactcaagc tcgccatgag
    30721 gagaataatc aggaagatga caatcgattt gaaaaacttc cttgtaacat aggcaaatgc
    30781 gttgtgtaac atagattccc tttctagatt ttgttttaat cattctatta aagtaagctc
    30841 aaattattta ctagtattgc gcgtttcagt cagtttctta tcctttaatt caagtgtaat
    30901 atctgacgct tgtgccactt ctttactgtg agttacgaca atcacacatt tacctgtttt
    30961 ctgggcaagt gatttgagta gttcgacaat atctccagca gttttaggat ccagatttcc
    31021 tgttggctca tcagctagaa taactggagc ttctgagacc aaactgcgag caatggcaac
    31081 acgttgctgt tgaccacctg ataactggag aacattccgc ttgatctggc tttcatccaa
    31141 accaagctca agaagtgtat tcttgcttgc ctttttgttg accaatcgga tattttccag
    31201 cggagaaaga taatctatca agttataatt ttgaaagacc agggaaatat ggtgcatgcg
    31261 atggtaagaa tagcccttct tacgaatatc ctctccttga aaaaggatag aaccttcaac
    31321 aggactatct agaccagcaa gtagggacaa gagtgtggat tttcctgctc ctgactcccc
    31381 aataatactg taaaattttc cgggttcaaa attataattg atctgatata ggactgcttc
    31441 agcagtattc ttataacggt aggtaacatc ttgtaattgt aataaagtca tgatttctcc
    31501 ttcttaacta atagatgata aaatttcttt cggtgatttt ctaaataaga ataggaaaca
    31561 aagggctaca gataagcaac taagcagaac tagaaaaaca taggattctg caaaagataa
    31621 gatgctagtt gataaactgc ttgctttggc tagtgtatct tgtaagcttg cctgatctcc
    31681 acttgctagt agagtttgga gtaggtaagt tgtgattccg tttcctgcaa caaatgctgg
    31741 aagcaaagct ccaagagata ccaaaactac ctctaaacag aattgtagga aaatcgagct
    31801 cttgcctttt ccaagtgcaa gtaaaatccc cacttcatag acccgttctc tcaaccagag
    31861 agacaaaacc agaattaagg ctccagctcc tgctatcaac atcccataaa ggaagatggt
    31921 caggaaggtt tggaaagttg caactgagtc tttgatttgt tcaaaagcct tgttttcctt
    31981 ttcgacttgg tagccttgat tttccaaggc caagttttct acctgcttca tgagtccgtc
    32041 catttcctta ggattttcta catagaagcg tgctgcactg acttgagctt cactattgcc
    32101 caaaagggtt tggctacttt catagtctgt aaagacttga ttttcactga agtcagaaga
    32161 caagcctgtg aatttctctt gttttttacc agaaaagatg ccgataatct caaactctac
    32221 tgtttgtcct tttccagatt cagactgacc agcatccaag ccaatcttgt catgaagtga
    32281 aagaccgttc ttcttagcca attcttcgtg gataaggatt ttcttggaat tccctttttg
    32341 aaggtgtcgc ccttctttta gattgaaagc cgaactggta aaggttacat ccttggatga
    32401 atcctcaaga gccgttaagc taaccaagtt attgtctgca gctgataaat catcacgctc
    32461 cacgctctgc tcgccagtca ctgcttcctt gtcttttagt tttgcgaccg tctcgagttc
    32521 aggagagaca ttttccagcc ccttaatctt gcttacagat gctaggtctg acaacttgaa
    32581 tgtctgacca ttctctatct tcttaataga aaaagatgta ttgagtgatt tataaagatt
    32641 gctttctact gttttgttgg acttcatcag agtcaaacag gctgaaattc cggccaataa
    32701 gaccaataaa atcagaaata aaataaaact tctcagtcgc tttctgctga cataagccca
    32761 agatctttgg attggattca tttgtcacct ccatatttgt aagactatta taaaacccaa
    32821 atatgaaatg tttatgaaat acgaaaaaaa aatatcgagt aggggataat ctctagcccc
    32881 tctca
//
LOCUS       DAVLBE010000021        31645 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.021, whole genome shotgun sequence.
ACCESSION   DAVLBE010000021 DAVLBE010000000
VERSION     DAVLBE010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31645)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31645)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31645
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.021"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            118..552
                     /locus_tag="VXB91_001019"
     CDS             118..552
                     /locus_tag="VXB91_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0470491.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQESVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPAKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAAQGGVVNGKELFSTDAEEEEEDFESGI"
     gene            564..1754
                     /locus_tag="VXB91_001020"
     CDS             564..1754
                     /locus_tag="VXB91_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="unsaturated chondroitin disaccharide hydrolase"
                     /protein_id="HEV0470492.1"
                     /translation="MIKKVTIEKIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELDHHDLGFLYTPSCMAEYKINGDGEAREATLKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSDQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEHYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            1765..2256
                     /locus_tag="VXB91_001021"
     CDS             1765..2256
                     /locus_tag="VXB91_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEV0470493.1"
                     /translation="MTMPNIIMTRIDERLIHGQGQLWVKYLGCNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKDVKDALTLVEGGVPIKE
                     INIGNIHNATGKEQVTRSIFLGEEDKAALKELSQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            2271..3050
                     /locus_tag="VXB91_001022"
     CDS             2271..3050
                     /locus_tag="VXB91_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEV0470494.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFAFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTADHVVEEEAHDDWI"
     gene            3037..3855
                     /locus_tag="VXB91_001023"
     CDS             3037..3855
                     /locus_tag="VXB91_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV0470495.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGENQEGFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPAKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVIIGIIGSWLKIIA"
     gene            3855..4148
                     /locus_tag="VXB91_001024"
     CDS             3855..4148
                     /locus_tag="VXB91_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEV0470496.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQMEQRQEYLA
                     SLTSGDEVLLLSGIHGKIISIQDDLVSLQIAKGVVIYVEKESVMGKTKELLFK"
     gene            4170..6071
                     /locus_tag="VXB91_001025"
     CDS             4170..6071
                     /locus_tag="VXB91_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HEV0470497.1"
                     /translation="MKEERRQFFERIDGNQCRDYILSHCSKDYEKVKSSLERLMDNRF
                     MFDSPWDMEPCSKIHQIQPMVWDQVFEDDPEWSYMLNRQEYLLQFMIGYVVEGDKDYI
                     QKCKFFLFDWIEQVREFSPQSLMTRTLDTGIRSFTWLKLLLLLLKFDLLEEKELEKIL
                     VSLEKQIDFMKSHYRAKYTLSNWGILQTIPMLAIYHFFADKMDLEEAYHFASEELKQQ
                     IETQILGDGSQFEQSILYHVEVYKALLDLCLLLPDLQDSYQELLEKMATYIQMMTGLD
                     GRTLAFGDSDSTETTEMLSLSAVVLNKEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     KRAWQPKFMSFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDA
                     GRYSYREIYERYLLKSAWSHSTCIVDGKAPERITGSWEYEYYPHSLFCHHKEREGMHY
                     IEGAYWSAEPDLPYLHRRKILMLVEDVWLLVDDIRCQGQHEALTQFILDKDVTYQDGK
                     INQLRLWSEVDFDLEDTIISPKYNELERSSKLTKRQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDDREVENALAFEVKNDETDKLILLLSEDICVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            6131..7132
                     /locus_tag="VXB91_001026"
     CDS             6131..7132
                     /locus_tag="VXB91_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV0470498.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
     gene            complement(7242..7577)
                     /locus_tag="VXB91_001027"
     CDS             complement(7242..7577)
                     /locus_tag="VXB91_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0470499.1"
                     /translation="MKSLARLLIIHVFISIFLFFALISGAVSHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLTNPVQWKFSIFLVVTIISSLAYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(7588..7830)
                     /locus_tag="VXB91_001028"
     CDS             complement(7588..7830)
                     /locus_tag="VXB91_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0470500.1"
                     /translation="MKKEKKQLRYPGLKAGSIYGTVIFFIIPLIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            complement(7846..8040)
                     /locus_tag="VXB91_001029"
     CDS             complement(7846..8040)
                     /locus_tag="VXB91_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0470501.1"
                     /translation="MNRVKEFRKELGISQLELAKDIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWEEDF"
     gene            8206..9156
                     /gene="rsmH"
                     /locus_tag="VXB91_001030"
     CDS             8206..9156
                     /gene="rsmH"
                     /locus_tag="VXB91_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HEV0470502.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPEGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNHYDYHDLVRIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKLVKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DLKPKMELVSRKPILPSAEELEANNRSHSAKLRVVRKIHK"
     gene            9168..9485
                     /gene="ftsL"
                     /locus_tag="VXB91_001031"
     CDS             9168..9485
                     /gene="ftsL"
                     /locus_tag="VXB91_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HEV0470503.1"
                     /translation="MAEKMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            9489..11741
                     /gene="pbpX"
                     /locus_tag="VXB91_001032"
     CDS             9489..11741
                     /gene="pbpX"
                     /locus_tag="VXB91_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2X"
                     /protein_id="HEV0470504.1"
                     /translation="MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY
                     ANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQ
                     MDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYE
                     PGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRIMTFSQGF
                     AHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSF
                     GQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAA
                     SLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGVT
                     DYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTA
                     KALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAP
                     NQQVLILSDKVEEVPDMYGWTKETAETLAKWLNIELEFQGSGSTVQKQDVRANTAIKD
                     IKKITLTLGD"
     gene            11743..12723
                     /locus_tag="VXB91_001033"
     CDS             11743..12723
                     /locus_tag="VXB91_001033"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HEV0470505.1"
                     /translation="MFISLSAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLITSVLVAFFFALFSSQFSNNVGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGVIFYLFYERGGDMLSVFGYQVHLGIFYIVFALFWLVGF
                     SNAVNLTDGVDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLGFFIFNHKP
                     AKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM"
     gene            13287..15392
                     /locus_tag="VXB91_001034"
     CDS             13287..15392
                     /locus_tag="VXB91_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEV0470506.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEF
                     AHYRTTGQLPGNAETDVQMPQQASGMKQDGVLAKLGRNLTAEAREGKLDPVIGRNKEI
                     QETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
                     EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     ETEKDKQEKAVEAEDFEAALNYKTRIAELEKKIENHTEDMKVTASVNDVAESVERMTG
                     IPVSQMGASDIERLKDMAHRLQDKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLF
                     VGSTGVGKTELAKQLALDMFGTQDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIATS
                     NAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLTKEDLSKIVDLMLA
                     EVNQTLAKKDIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     AKHLEADMEDGVLVIREKA"
     gene            complement(15688..16170)
                     /locus_tag="VXB91_001035"
     CDS             complement(15688..16170)
                     /locus_tag="VXB91_001035"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HEV0470507.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
     gene            complement(16265..17749)
                     /locus_tag="VXB91_001036"
     CDS             complement(16265..17749)
                     /locus_tag="VXB91_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HEV0470508.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQPAADAFRNQLEKNGIDSYLHYPIKGYPTDMDHIISPEGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMND
                     LGITPADRKVAVVARQKAEETGGPALAFELPNGEIVTGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDATRAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            17902..19512
                     /locus_tag="VXB91_001037"
     CDS             17902..19512
                     /locus_tag="VXB91_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001156816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HEV0470509.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNGDGVGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIATIFGTMEDMDQLIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENPNSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGDKDLLTVGETWGATPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVPIEEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTGQPWLAVNPNYEMINVQEALANPDSIFYTYQKL
                     VQIRKENSWLVRADFELLDTADKVFAYIRKDGDRRFLVVANLSNEEQDLTVEGKVKSV
                     LIENTLAQEVFEKQILVPWDAFCVEMTD"
     gene            complement(19643..21073)
                     /locus_tag="VXB91_001038"
                     /pseudo
     CDS             complement(19643..21073)
                     /locus_tag="VXB91_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398391.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISNCY family transposase"
     gene            21230..22675
                     /gene="cps4A"
                     /locus_tag="VXB91_001039"
     CDS             21230..22675
                     /gene="cps4A"
                     /locus_tag="VXB91_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4A"
                     /protein_id="HEV0470510.1"
                     /translation="MSRRFKKSGSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNILAF
                     RYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLVFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSEIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLT
                     VNQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADG
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKLIDLLGGVDVHNDQ
                     EFSALHRKFLFPVGNVHLDSEQALGFVRERYSLADGDRDRGRNQQKVIVAILQKLTST
                     EALKNYSTIINSLQDSIQTNMPLETMINLVNAQLESGGTYKVNSQDLKGTDRMDLPSY
                     AMPDSNLYVMEIDDSSLAVVKAAIQDVMEGR"
     gene            22677..23408
                     /locus_tag="VXB91_001040"
     CDS             22677..23408
                     /locus_tag="VXB91_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HEV0470511.1"
                     /translation="MIDIHSHIVFDVDDGPKSIEESKALLREAYNQGVRMIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVADDLVIAYGAEIYYTLDALEKLEKKEIPTLNDS
                     RYALIEFSMHTSYREIHAGLSNILMLGITPVIAHIERYDALENNEKRVRELIDMGCYT
                     QINSYHVLKPKFFGEKYKFMKKRARYFLERDLVHVVASDMHNLDSRPPYMQQAYDIIA
                     KKYGAKKAKEFFVDNPRKIIMDQLI"
     gene            23417..24109
                     /gene="cpsC"
                     /locus_tag="VXB91_001041"
     CDS             23417..24109
                     /gene="cpsC"
                     /locus_tag="VXB91_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     CpsC"
                     /protein_id="HEV0470512.1"
                     /translation="MKEQNTLEIDVLQLFRALWKRKLVILLVAIITSSVAFAYSTFVI
                     KPEFTSTTRIYVVNRNQEEKSGLTNQDLQAGSYLVKDYREIILSQDILEEVISDLKLD
                     LTPKGLANKIKVTVPVDTRIVSVSVNDRVPEEASRIANSLREVAAQKIISITRVSDVT
                     TLEEARPAISPSSPNIKRNTLIGFLAGGIGTSVIVLLLELLDTHVKRPEDIEDTLQMT
                     LLGVVPNLSKLK"
     gene            24119..24802
                     /gene="cpsD"
                     /locus_tag="VXB91_001042"
     CDS             24119..24802
                     /gene="cpsD"
                     /locus_tag="VXB91_001042"
                     /EC_number="2.7.10.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis tyrosine autokinase
                     CpsD"
                     /protein_id="HEV0470513.1"
                     /translation="MPTLEIAQKKLEFIKKAEEYYNALCTNIQLSGDKLKVISVTSVN
                     PGEGKTTTSVNIARSFARTGYKTLLIDGDTRNSVISGVFKSREKITGLTEFLSGTADL
                     SHGLCDTNIENLFVIQSGSVSPNPTALLQSKNFNDMIETLRKYFDYIIVDTAPIGIVI
                     DAAIITQKCDASILVTAIGEVNKRDVQKAKQQLEQTEKLFLGVVLNKLDISVDKYGVY
                     GSYGNYGKK"
     gene            24818..26185
                     /locus_tag="VXB91_001043"
     CDS             24818..26185
                     /locus_tag="VXB91_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEV0470514.1"
                     /translation="MDEKGLKIFLAVIQSIIVILLVYFLSFVRETELERSSMVILYLL
                     HFFVFYFSSYGNNFFKRGYLVEFNSTIRYIFFFAIAISVLNFFIAERFSISRRGMVYF
                     LTLEGISLYLLNFLVKKYWKHVFFNLKNSKKILLLTVTKNMEKVLDKLLESDELSWKL
                     VAVSVLDKSDFQHDKIPVIEKEKIIEFATHEVVDEVFVNLPGESYDIGEIISRFETMG
                     IDVTVNLKAFDKNLGRNKQIHEMVGLNVVTFSTNFYKTSHVISKRILDICGATIGLIL
                     FAIASLVLVPLIRKDGGSAIFAQTRIGKNGRHFTFYKFRSMRIDAEAIKEQLMDQNTM
                     QGGMFKIDNDPRVTKIGRFIRKTSLDELPQFWNVFIGDMSLVGTRPPTVDEYDQYTPE
                     QKRRLSFKPGITGLWQVSGRSKITDFDDVVKLDVAYIDNWTIWKDIEILLKTVKVVFM
                     RDGAK"
     gene            26191..26934
                     /locus_tag="VXB91_001044"
     CDS             26191..26934
                     /locus_tag="VXB91_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WecB/TagA/CpsF family glycosyltransferase"
                     /protein_id="HEV0470515.1"
                     /translation="MNERMQILGVTIDPLTMKETVDAVEQYVLKKHPLHLMGVNADKI
                     NQCHEDEKIKKIVNESGIINADGASVVLASKFLGTPVPERVAGIDLMQCLLELSNKKG
                     YSVYFFGAKEEILQDMLKVFKQRYPNLNVVGYRNGYFSPEDEKKIQEDIKGGKPDFVF
                     VGITSPKKEYIIQSFMDNGINAVFMGVGGSFDVLSGHIKRAPLWMQKLNLEWLFRVVN
                     EPKRLFKRYFIGNVTFIKRVLDEKRKSKK"
     gene            26909..27994
                     /locus_tag="VXB91_001045"
     CDS             26909..27994
                     /locus_tag="VXB91_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000834366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEV0470516.1"
                     /translation="MKSENQKNNILHISRTMDIGGAERIVYQLSSDLKDEFDSVHVAS
                     TGGLWESKLLSKGVQHHKILDVDSKNPLTMVKILSSFYRIIKNNDITIVHTHHRMAAF
                     YIRLLKIINPKLIHVYTAHNVFKNKLPLYKFSLKKAYCVAVSKAVNDNLKHDVGISDS
                     TVIYNGVVFEKTDKLVGEIVNYNGIKLGCIARLSEQKGLTYLIDAMSLVKHRNITLFI
                     VGDGELRDELENKVKQLNLQKSVIFLGYRKDIVECINSFDYLVSSSLYEGFGLNAIEA
                     FMKGKTMVSSDIPGINEVVNNKNGILVPVKDDVALARAIEKLATDKKLREKLAYQAKK
                     DYETKFNYSLFLDNYRRLYRKLMGESK"
     gene            27991..29079
                     /gene="wecB"
                     /locus_tag="VXB91_001046"
     CDS             27991..29079
                     /gene="wecB"
                     /locus_tag="VXB91_001046"
                     /EC_number="5.1.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000758382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (non-hydrolyzing)"
                     /protein_id="HEV0470517.1"
                     /translation="MKKVMLVFGTRPEAIKMCPLVNELKQNDSIKTLVCVTGQHKEML
                     EQVLEVFKVVPDYDLGIMKANQTLFTITTSILDKIQAVLEKEKPDLVLVHGDTTTTFA
                     TALAAFYMGIKVGHVEAGLRTYNLQSPFPEEFNRQTTSIIADYHFAPTEVAKENLLRE
                     DRKNIFVTGNTVIDALKTTVQDNYHHPILEWAKGSKLIMLTAHRRENLGKPMENMFNA
                     VNRILNEFEDVKVVYPIHKNPKVRELASKVFGDNERMKIIEPLEVIDFHNFMNQSYMI
                     LTDSGGVQEEAPSLGKPVLVMRDTTERPEGVVAGTLKLVGTEEENIYSNFKLLLEDET
                     EYNKMSKASNPYGDGMTCKRIVDIILEV"
     gene            29121..30260
                     /locus_tag="VXB91_001047"
     CDS             29121..30260
                     /locus_tag="VXB91_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HEV0470518.1"
                     /translation="MIKRKIYIICVLLSYFLPSFFTVGSMATLFALLSTLVKLFVTFD
                     YIPKVLLQHKVTLIDILVVLFLFFQAFAAFQSQTLYLNYVGGQFFLLGLYSFLKHFLL
                     LDCKTTIKSLFLTFILFLCVQVITQLLFPVGFDSLHPTGDNRLYFLGRKNIATPYIIV
                     GLGGFYLLNKKMNEFISLKEIIFLGLFGILSFLTQSSTAIICYGLFIFIRLLGLKENI
                     GKLYSLVSMAVYVCFSLSIIFSQSTILSTFTAIFSKNATFSGRINIWQLAIRIFEENF
                     WFGRGLNVNFNAWTNGIIVNSAHNTLLDILARTGIFPGVLFIVLLMNLFLGKYRIESK
                     TLLAMLASFMIYITMETSSMSILLLIIVLCVYWPRGEEKLHEQVT"
     gene            30244..31113
                     /locus_tag="VXB91_001048"
     CDS             30244..31113
                     /locus_tag="VXB91_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HEV0470519.1"
                     /translation="MSKLLNTIYYRLFRLYKKIYLQVFSKKTVDILGEKANLENELIV
                     SFTTIPSRLNYLPSMIKSIFNQTIIPNRFIMYVYKDEFEGINLESILELEIKNGLEIV
                     YVDENLRSHKKYFYAMKDNPNSIVVLVDDDIIYPRNTIKKLIASYRIYPQCVSAMRCH
                     RIKLFSDGSLYPYNQWEYEISGATIPSYFNFFTSGGGTLFPPCTRNEDLFNKKNIREL
                     SFLADDVWLNFLVVKNGIKTVKATRYKGTPLTIDDNPEESLVYLNTVYDNNNDKCIRN
                     MVEYYQINFTEDK"
     gene            31113..>31645
                     /locus_tag="VXB91_001049"
     CDS             31113..>31645
                     /locus_tag="VXB91_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HEV0470520.1"
                     /translation="MNVEKNLKRGIFYTAIGKYSNVVIQLLVTAILSRILSPVEYGIV
                     AVVNVFLLFFQMLADSGIGPAIVQNKELNKSDLISIFSLTIYSGIVLSCIFALLGYPM
                     GVLYGETIYVSLFPLLGLCVLFYTITIVPQAILMKTMNFKIVNFLTIFSNIASGLVGV
                     ILAVSHFGVYSLIFSNIV"
BASE COUNT         9746 a         5259 c         6892 g         9748 t
ORIGIN      
        1 aaaaagataa tgaaagcgct aatatttttt taaaaaaact attgacaaga taaaaataaa
       61 ggattacaat ggggaatata aagtaaaccg gtaaacctaa acaagaaagg agaaaagatg
      121 aaaattgtac ttgtagggca tggacatttt gctacaggga tttatagttc tttacaattg
      181 attgcaggca atcaagaaag tgtggaggcg attgactttg tggaaggaat gtcagcagat
      241 gaactcaagc aaaaaatctt acttgcaatt tcaaatgaag aagaagtttt aatcctaagt
      301 gatctcttgg gaggatcgcc attcaaggtt tcttctacca taatgggaga aaatccagcc
      361 aaaacaatga atgttctctc gggtttgaac ttagccatgt taatggaagc agtctttgct
      421 agaatggctc atagctttga tgaggttgtt aataaatcag tagtggcggc ccagggcgga
      481 gtcgtaaatg gtaaagaatt gttttcaacg gatgcagagg aagaggaaga agatttcgaa
      541 tcgggtattt aaagggtaaa agaatgataa aaaaggttac gattgaaaaa ataaaatcgc
      601 ctgagcgctt cttagaagta ccacttctga cgaaagaaga agtcggccag gcaatcgata
      661 aggttattcg gcagttagaa ctcaaccttg actatttcaa ggaagatttc cctacgccag
      721 ctacctttga taatgtctat ccaatcatgg ataacacgga atggaccaat ggtttctgga
      781 caggagaact gtggttggct tatgaataca gtcaacagga tgcatttaaa aacatcgctc
      841 ataaaaatgt tctttctttc ctggatcgtg tcaataagag agtagaattg gatcaccatg
      901 atctcggctt cttgtacaca ccgtcttgta tggctgaata taagataaat ggagatggag
      961 aggctagaga agcaaccttg aaagctgcag ataagttgat tgaacgctat caagaaaaag
     1021 gtggttttat tcaagcttgg ggagacttgg gcaagaaaga gcattaccgt ttgattatcg
     1081 actgcttgct caatatccaa ctcttattct ttgcttatca agaaacaggc gatcaaaaat
     1141 actacgatat tgcagaaagt catttctatg cttcagctaa taatgtaatc cgtgatgacg
     1201 cttcgtcctt ccacaccttc tattttgatc ctgagacagg tcaacccttt aaaggtgtaa
     1261 cgagacaagg gtatagtgat gattcatgct gggcacgtgg tcaatcatgg ggagtctatg
     1321 gtattccttt gacttatcgt cacttaaaag acgagtcctg ctttgacttg tttaagggtg
     1381 tgaccaatta tttcttgaat cgtctgccaa aagatcatgt gtcctattgg gatttgattt
     1441 ttaatgatgg tagtgatcaa tcacgagatt cttcagcaac agctatcgcc gtctgtggga
     1501 ttcatgaaat gctaaaacat ctcccagagg tggatgctga caaagatatt tataaacatg
     1561 ctatgcatgc catgcttcgt tccttgatcg aacattatgc aaatgatcaa tttacccctg
     1621 gtgggacaag tctcctccac ggtgtgtact catggcattc aggtaaagga gtggatgaag
     1681 gcaatatctg gggtgactac tattacctag aagcccttat ccgtttctac aaagactgga
     1741 acctatattg gtaggaggag aaatatgaca atgccaaata ttattatgac ccgtatcgat
     1801 gaacggttga ttcatggaca aggacaactt tgggtaaaat acctaggttg taatacggtc
     1861 attgttgcca atgacgaagt aagcacggac aagatgcaac aaactctgat gaaaacagtt
     1921 gtgccagact cagttgccat gcgtttcttc cctttgcaaa aggtgattga tatcattcac
     1981 aaggctaatc ctgctcaaac gatctttatc gttgtaaagg atgtgaagga cgctttaacc
     2041 ttggtagaag gtggtgtccc tatcaaagaa atcaatattg ggaacattca caatgctact
     2101 ggtaaagagc aagtgacacg ctccatcttc ctgggtgaag aggacaaggc agccctcaag
     2161 gaattaagcc aaactcatca agtaacattt aatacgaaaa caactccaac aggaaatgat
     2221 ggagctgttc aagtcaacat tatggactat atttaaaaga ggagatcgtt atgtcgatta
     2281 atgtatttca agcgatttta attggattat ggacagcttt ctgttttagt ggaatgctat
     2341 taggaattta caccaataga tgtattgttc tgtcatttgg tgtcggaatt attctaggtg
     2401 atctgcctac tgctcttgca atgggagcta ttggtgaatt ggcttatatg ggattcggtg
     2461 ttggtgctgg aggtactgtt ccaccaaacc caatcggacc tggtatcttt ggtaccttga
     2521 tggctatcac tagtgctggt aaagtcagtc cagaagcggc tcttgccctc tctactccga
     2581 ttgctgtggc gattcaattc ttacaaactt tcgcctacac tgtacgtgct ggtgcgcctg
     2641 aaacggcgat gaagcacttg aaaaaccata atttgaagaa attcaagttc actctaaatg
     2701 caacaatttg gttgtttgcc tttattggat ttaccttggg ttgcttgggt gccctttcaa
     2761 tggatacctt gttgaaactc gtagactaca ttccaccggt attgcttaca ggtttgacag
     2821 ttgctggtaa aatgctccca gctatcggtt ttgcgatgat cttgtcagtg atggctaaga
     2881 aagagttgat tccctttgtc ttgttgggat atgtttgtgc agcttatcta aacatcccaa
     2941 caattggtat tgcaattgta ggtactatct ttgctttgat tgaattttat aacaagccaa
     3001 aaacagcgga tcatgtggta gaggaggaag cacacgatga ctggatctaa caaattaaca
     3061 aaacgtgatt atcttaaaac gtctttgcgg gcattctttt gtcaaaatgg atttaactat
     3121 agtaactatc aagggttggg atatgccaat gtgatgtatc ctgctttgaa aaaacactat
     3181 ggagagaatc aggaaggttt ctaccaagcc ttggaagaaa actgtgaatt ctataatacc
     3241 aacccacact tcctgccttt tattaccagc ttgcatcttg taatgttgga aaatggccgt
     3301 ccggcaaaag aaacacgtag catcaagatg gccttgatgg gaccattagc aggtattggg
     3361 gattctctct ctcaattctg tttagctcca ttgttctcaa ccatcgcagc ttcgtttgct
     3421 caagaaggct tggttgtcgg tccaatcttg ttcttccttg cgatgaatac gattttaaca
     3481 gcgattaaat tgtcaactgg tctgtatgga tacaaactag gaacgactgt gattgataaa
     3541 ctaagcgagc agatggcaac gatttctcgt attgccaata ttattggtgt aaccgtaatt
     3601 gctggtttgg cagcgacatc tgttaagatt atggtaccga tcacctttgc tgcaggggaa
     3661 gttaaagcag acgctaaaca aagtatcgta agtattcagg gaatgcttga taaggttgct
     3721 ccagctcttc taccagccct atttacactt ttagtttact acttgatcaa agaaaagaaa
     3781 tggacaacat ataaactcgt tattttaaca gttatcatcg gaattatcgg aagctggctt
     3841 aagattatag cttaatggat acaacattgt tttatggaat agtgattgtc ttggcagtga
     3901 gtcccctttt actgtcaagc tttcattcta ttcgtcagca aaagttgctt cgcaaacaga
     3961 tggagcaacg acaagagtat ttagcttctt taacatctgg tgatgaagtg ttgttattgt
     4021 ctggaattca tggaaaaatc atttctatcc aagatgactt ggtctccttg cagattgcaa
     4081 aaggtgtggt catctatgta gaaaaggaaa gtgtaatggg aaagacaaaa gaactgcttt
     4141 ttaagtagtt ctttttctgg taatagataa tgaaagaaga aagaagacaa ttttttgaaa
     4201 gaatcgatgg aaaccaatgt cgtgattata tcttgtccca ctgttcaaaa gactatgaga
     4261 aagtcaagag ttcccttgaa cgcttgatgg acaatcgttt tatgtttgat agtccttggg
     4321 atatggagcc ttgttcaaaa atccatcaaa tccagccgat ggtatgggat caagtatttg
     4381 aagatgatcc agaatggtct tatatgctca atcgacaaga atatctcttg cagtttatga
     4441 tagggtatgt ggtagaagga gataaggact atattcaaaa gtgcaagttc tttctatttg
     4501 attggattga gcaggtgaga gaattttctc ctcaatcctt gatgactaga accttggata
     4561 ccggtattcg ttcctttact tggttgaaac tactcttgct cctcttgaaa tttgacttgc
     4621 tagaggagaa agaactagag aaaattttgg tcagtctaga aaagcagatt gactttatga
     4681 aaagccacta tcgcgccaag tacaccctta gtaactgggg aattttacaa acaattccga
     4741 tgcttgctat ctatcatttc tttgcagata agatggacct agaagaagct taccattttg
     4801 cttcagagga gttgaaacag caaattgaga cacagatttt aggagatgga agccagtttg
     4861 aacagtcgat tctctatcat gtagaggttt ataaagcctt gctggatttg tgtctcttgc
     4921 ttccagactt gcaagatagt taccaagagt tgctggaaaa gatggcgacc tatattcaaa
     4981 tgatgacagg cttagatgga cgaactttgg cttttggtga tagcgattct acagaaacga
     5041 cagaaatgtt gagcctgtct gctgtggttt tgaacaagga agaccttctt aacggtctgg
     5101 atgttaaagt cgatttgctt agcctcttgt tcctggggcg agaaaaggtc aagcgactgc
     5161 aggaatttga aaagcgagct tggcagccta agttcatgag ctttgaagac tctggacatg
     5221 tctgcattaa ggatgaacat cgttatctat ttttcaaaaa tggtccgcta ggaagtgccc
     5281 atagccatag tgacgagaat agtttttgct tacagtatca aggccaacct attttcatag
     5341 atgctgggcg ttattcttat cgggagatat atgaacgtta tctcttaaag agtgcttgga
     5401 gtcattcgac ctgcattgta gatgggaaag ctccggaaag aatcacggga tcctgggaat
     5461 atgaatacta tcctcactcc ctgttttgtc accataaaga aagggaggga atgcattata
     5521 ttgaaggggc ttattggtca gcagaacctg atttgcctta tcttcacagg agaaaaatcc
     5581 tcatgttggt agaggatgtc tggctcttgg tagatgacat caggtgtcaa ggtcagcatg
     5641 aggcgttgac tcagtttatc cttgacaagg atgtgaccta tcaagatggg aaaatcaatc
     5701 agttgagact atggagtgaa gttgattttg atttggaaga taccatcatt tctcctaaat
     5761 acaatgagct tgaaagaagt agcaaactca ccaagcgcca attctttgag aatcagatgc
     5821 tggattatac catcattgcg catgagagtt ttgaaatcat ccgtcattct gtctaccaga
     5881 cagatgatcg tgaagtggaa aatgctctgg cttttgaagt gaaaaatgac gaaacagaca
     5941 agctgattct gttattaagc gaggatattt gtgtaggtga aaaattgtgc ctcgttgacg
     6001 gaacaaaaat gcgtggaaaa tgtctagtat atgataaaat aaatgagaga atgattcgct
     6061 tgcagtgcta gaaataggca ttttgaatag tgaatatgtt ataataagta ttagtaggag
     6121 gtgttttaga ttggagaaga aactgaccat aaaagacatt gcggaaatgg ctcagacctc
     6181 gaaaacaacc gtgtcatttt acctaaacgg gaaatatgaa aaaatgtccc aagagacacg
     6241 tgaaaagatt gaaaaagtta ttcatgaaac aaattacaaa ccgagcattg ttgcgcgtag
     6301 cttaaactcc aaacgaacaa aattaatcgg tgttttgatt ggtgatatta ccaacagttt
     6361 ctcaaaccaa attgttaagg gaattgagga catcgccagc cagaatggct accaggtaat
     6421 gataggaaat agtaattaca gccaagagag tgaggaccgg tatattgaaa gcatgcttct
     6481 cttgggagta gacggcttta ttattcagcc gacctctaat ttccgaaaat attctcgtat
     6541 catcgatgag aaaaagaaga aaatggtctt ttttgatagt cagctctatg aacaccggac
     6601 tagctgggtt aaaaccaata actatgatgc cgtttatgac atgacccagt cctgtatcga
     6661 aaaaggttat gaacattttc tcttgattac agcggatacg agtcgtttga gtactcggat
     6721 tgagcgggca agtggttttg tggatgcttt aacagatgct aatatgcgtc acgccagtct
     6781 aaccattgaa gataagcata cgaatttgga acaaattaag gaatttttac aaaaagaaat
     6841 cgatcccgat gaaaaaactc tggtatttat ccctaactgt tgggccctac ctctagtctt
     6901 taccgttatc aaagagttga attataactt gccacaagtt gggttgattg gttttgacaa
     6961 tacggagtgg acttgctttt cttctccaag tgtttcgacg ctggttcagc cctcctttga
     7021 ggaaggacaa caggctacaa agattttgat tgatcagatt gaaggccgca atcaagaaga
     7081 aaggcaacaa gtcttggatt gtagtgtgaa ttggaaagag tcgactttct aaaatgaagg
     7141 aaaatgactt gcaatctctg ttaagaaata aaataatccc acctagaaca agctaggtgg
     7201 gattatttgc ctatgaaatg agaaattatg ggagcaagct cctaaatcaa ctgtttttga
     7261 tctacttctt taactacttg ataaaagtta tagaagtagg ccaaacttga aatgatggtt
     7321 acgactagga atattgaaaa tttccattgg acagggttgg ttaaaagttg tggaaaggat
     7381 atgaggagaa agaagagggc tgcgttgagg acaggtatcc gttttgattg tattttctca
     7441 agtcctttat tgagcgcagg aagaaagagg agtaggagta gtaaaactgt atgagaaaca
     7501 gctcctgaaa taagggcaaa gaaaaggaaa atactgataa aaacatgaat gatcagtagt
     7561 ctagctagtg atttcataag gtacctccta atcctggtct tttttagctc ttgcaatacg
     7621 aagtgagtcg acaatatgta tcatcactcc gaaaaagaaa gctcccagta tagttttaaa
     7681 aatatgtttt gtatttagaa gagaactgat aaaatttgga ttttcacttg ttagggtatc
     7741 aatgagtgga attataaaaa atatcactgt tccataaatc gaacctgctt tcagaccagg
     7801 ataacgtaac tgtttctttt cttttttcat gagtttgctc cttttttaaa aatcttcctc
     7861 ccaaaagaga ctgttgaggt cagtttggag gctgcgggcg agattgagac agagttccaa
     7921 ggttggattg tacttgtcgt tttcaatcat attgatagtc tgtctcgaga caccgatatc
     7981 cttggcgagt tcgagctggg aaatacccaa ttccttgcga aattctttca cacgattcat
     8041 ctggtctcct ttctgattta tgtcgtatat atttgactat attatagtct tttaaacata
     8101 aagtgtcaag tatttttgac atattttttg aagaaatagt agtctccttg tcctatttgt
     8161 ctgacaagtg caagctggtc ggatttgtgg taaaatagat aagatatgac aaaagaattt
     8221 catcatgtaa cggtcttact ccacgaaacg attgatatgc ttgacgtaaa gcctgaaggt
     8281 atctacgttg atgcgacttt gggcggagca ggacatagcg agtatttatt aagtaaatta
     8341 agtgaaaaag gccatctcta tgcctttgac caggatcaga atgccattga caatgcgcaa
     8401 aaacgcttgg caccttacat tgagaaggga atggtgacct ttatcaagga taacttccgt
     8461 catttacagg cacgtttgcg cgaagctggt gttcaggaaa ttgatggaat ttgttatgac
     8521 ttgggagtgt ctagtcctca attggaccag cgtgagcgtg gtttttctta taaaaaggat
     8581 gcgccactgg acatgcggat gaatcaggat gctagtctga cagcctatga agtggttaat
     8641 cattatgact atcatgattt ggttcgtatt ttcttcaaat acggtgagga taaattctct
     8701 aaacagattg cgcgtaagat tgagcaagcg cgtgaagtga agccgattga gacaacgact
     8761 gagttagcag agattatcaa gttggtcaaa cctgccaagg aactcaagaa gaagggtcat
     8821 cctgctaagc agattttcca ggctattcga attgaagtca atgatgaact gggagcggca
     8881 gatgagtcca tccagcaggc tatggatatg ttggctctgg atggtagaat ttcagtgatt
     8941 acctttcatt ccttagaaga ccgcttgacc aagcaattgt tcaaggaagc ttcaacagtt
     9001 gaagttccaa aaggcttgcc tttcatccca gatgatctca agcccaagat ggaattggtg
     9061 tcccgtaagc caatcttgcc aagtgcggaa gagttagaag ccaataaccg ctcgcactca
     9121 gccaagttgc gcgtggtcag aaaaattcac aagtaagagg gaaaaagatg gcagaaaaaa
     9181 tggaaaaaac aggtcaaata ctacagatgc aacttaaacg gttttcgcgt gtggaaaaag
     9241 ctttttactt ttccattgct gtaaccactc ttattgtagc cattagtatt atttttatgc
     9301 agaccaagct cttgcaagtg cagaatgatt tgacaaaaat caatgcgcag atagaggaaa
     9361 agaaaaccga attggacgat gccaagcaag aggtcaatga actattacgt gcagaacgtt
     9421 tgaaagaaat tgccaattca cacgatttgc aattaaacaa tgaaaatatt agaatagcgg
     9481 agtaagatat gaagtggaca aaaagagtaa tccgttatgc gaccaaaaat cggaaatcgc
     9541 cggctgaaaa cagacgcaga gttggaaaaa gtctgagttt attatctgtc tttgtttttg
     9601 ccattttttt agtcaatttt gcggtcatta ttgggacagg cactcgcttt ggaacagatt
     9661 tagcgaagga agctaagaag gttcatcaaa ccacccgtac agttcctgcc aaacgtggga
     9721 ctatttatga ccgaaatgga gtcccgattg ctgaggatgc aacctcttat aatgtctatg
     9781 cggtcattga tgagaactat aagtcagcaa cgggtaagat tctttacgta gaaaaaacac
     9841 aatttaacaa ggttgcagag gtctttcata agtatctgga catggaagaa tcctatgtaa
     9901 gagagcaact ctcgcaacct aatctcaagc aagtttcctt tggagcaaag ggaaatggga
     9961 ttacctatgc caatatgatg tctatcaaaa aagaattgga agctgcagag gtcaagggga
    10021 ttgattttac aaccagtccc aatcgtagtt acccaaacgg acaatttgct tctagtttta
    10081 tcggcctagc tcagctccat gaaaatgaag atggaagcaa gagcttgctg ggaacctctg
    10141 gaatggagag ttccttgaac agtattcttg cagggacaga cggcattatt acctatgaaa
    10201 aggatcgtct gggtaatatt gtacccggaa cagaacaagt ttcccaacga acgatggacg
    10261 gtaaggatgt ttatacaacc atttccagcc ccctccagtc ctttatggaa acccagatgg
    10321 atgcttttca agagaaggta aaaggaaagt acatgacagc gactttggtc agtgctaaaa
    10381 caggggaaat tctggcaaca acgcaacgac cgacctttga tgcagataca aaagaaggca
    10441 ttacagagga ctttgtttgg cgtgatatcc tttaccaaag taactatgag ccaggttcca
    10501 ctatgaaagt gatgatgttg gctgctgcta ttgataataa tacctttcca ggaggagaag
    10561 tctttaatag tagtgagtta aaaattgcag atgccacgat tcgagattgg gacgttaatg
    10621 aaggattgac tggtggcaga ataatgactt tttctcaagg ttttgcacac tcaagtaacg
    10681 ttgggatgac cctccttgag caaaagatgg gagatgctac ctggcttgat tatcttaatc
    10741 gttttaaatt tggtgttccg acccgtttcg gtttgacgga tgagtatgct ggtcagcttc
    10801 ctgcggataa tattgtcaac attgcgcaaa gctcatttgg acaagggatt tcagtgaccc
    10861 agacgcaaat gattcgtgcc tttacagcta ttgctaatga cggtgtcatg ctggagccta
    10921 aatttattag tgccatttat gatccaaatg atcaaactgc tcggaaatct caaaaagaaa
    10981 ttgtgggaaa tcctgtttct aaagatgcag ctagtctaac tcggactaac atggttttgg
    11041 tagggacgga tccggtttat ggaaccatgt ataaccacag cacaggcaag ccaactgtaa
    11101 ctgttcctgg gcaaaatgta gccctcaagt ctggtacggc tcagattgct gacgagaaaa
    11161 atggtggtta tctagtcggg gtaaccgact atattttctc ggctgtatcg atgagtccgg
    11221 ctgaaaatcc tgattttatc ttgtatgtga cggtccaaca acctgaacat tattcaggta
    11281 ttcagttggg agaatttgcc aatcctatct tggagcgggc ttcagctatg aaagactctc
    11341 tcaatcttca aacaacagct aaagctttgg agcaagtaag tcaacaaagt ccttatccta
    11401 tgcctagtgt caaggatatt tcacctggtg atttagcaga agaattgcgt cgcaatcttg
    11461 tacaacccat cgttgtggga acaggaacga agattaaaaa cagttctgct gaagaaggga
    11521 agaatcttgc cccgaaccag caagtcctta tcttatctga taaagtagag gaagttccgg
    11581 atatgtatgg ttggacaaag gagactgctg agacccttgc taagtggctc aatatagaac
    11641 ttgaatttca aggttcgggc tctactgtgc agaagcaaga tgttcgtgct aacacagcta
    11701 tcaaggacat taaaaaaatt acattaactt taggagacta atatgtttat ttccctcagt
    11761 gctggaattg tgacattttt actaacttta gtaggaattc cggcctttat ccaattttat
    11821 agaaaggcgc aaattacagg ccagcagatg catgaggatg tcaaacagca tcaggcaaaa
    11881 gctgggactc ctacaatggg aggtttggtt ttcttgatta cttctgtttt ggttgctttc
    11941 tttttcgccc tatttagtag ccaattcagc aataatgtgg gaatgatttt gttcatcttg
    12001 gtcttgtatg gcttggtcgg atttttagat gactttctca aggtctttcg taaaatcaat
    12061 gaggggctta atcctaagca aaaattagct cttcagcttc taggtggagt tatcttctat
    12121 cttttctatg agcgcggtgg cgatatgctt tctgtctttg gttatcaagt gcatctaggg
    12181 attttctata ttgtcttcgc tcttttctgg ctagtcggtt tttcaaacgc agtaaacttg
    12241 acagacggtg ttgacggttt agctagtatt tccgttgtga ttagtttgtc tgcctatgga
    12301 gttattgcct atgtgcaagg tcagatggat attcttctag tgattcttgc catgattggt
    12361 ggtttgctcg gtttcttcat ctttaaccat aagcctgcca aggtctttat gggtgatgtg
    12421 ggaagtttgg ccctaggtgg gatgctggca gctatctcta tggctctcca ccaagaatgg
    12481 actctcttga ttatcggaat tgtatatgtt tttgaaacaa cttctgttat gatgcaagtc
    12541 agttatttca aactgacagg tggtaaacgt attttccgta tgacgcctgt acatcaccat
    12601 tttgagcttg ggggattgtc tggtaaagga aatccttgga gcgagtggaa ggttgacttc
    12661 ttcttttggg gagtgggact tctagcaagt ctcctgaccc tcgcaatttt atatttgatg
    12721 taagaatggc accctgatgt ttcagggtgt ttttgtgttt aaatacacaa tgaaaatcaa
    12781 agaacaaact agaaagctaa ctttaggctg ctcaaaatat agtagattga aactagaata
    12841 gtacacatct acttctaaaa tattgttaga aatcgatttg actgtcctga tcgatttgtc
    12901 ctgttcttat ttcattttaa tatacagttt tgaggttgta gataaggaga agctgatgtg
    12961 gtttgaagag gttttcgaag agtgtaaaaa aatattggtc agttaaagtc aaaactcttg
    13021 accttttctg actaatgtag tatattatga acgtaaggta aatgaaagcc ttactagaac
    13081 acttatttaa agtaaaatag aaagaggtgg gtctatgttt catctagaaa tcttcagaag
    13141 taaagatagt ctactcctgc ttgaaaaaga aaaaccagaa atagtacgta gggtagcgat
    13201 ctagctagtc taaatttttt aaaacaatgg tcaaagatag tcaatatcag taatcataac
    13261 taagtaaaca aaaagaggta aagaatatga ataacaactt taataatttt aataacatgg
    13321 atgatttatt taaccaattg atgggtggta tgcgaggata cagttctgaa aatcgccgtt
    13381 acttaattaa tggacgcgaa gtcacacctg aggaatttgc tcactatcgt acgactggtc
    13441 aattaccagg aaatgcagaa actgatgtgc aaatgccaca acaggcatca ggtatgaaac
    13501 aagacggtgt ccttgcaaaa ctaggtcgaa acttgacagc agaagcgcgt gagggcaagt
    13561 tggatcctgt tatcggacga aacaaggaaa ttcaagaaac atctgaaatc ctctcacgcc
    13621 gcaccaagaa caatcctgtt ttggtcggag atgcaggtgt tggtaagaca gcagttgtcg
    13681 aaggtctagc gcaagccatt gtgaacggag atgttcctgc tgctatcaag aacaaggaaa
    13741 ttatttctat tgatatctca ggtcttgagg ctggtactca ataccgtggt agctttgaag
    13801 aaaatgtcca aaacttagtc aatgaagtga aagaagcagg gaatattatc ctcttctttg
    13861 atgaaattca ccaaattctt ggtgctggta gcactggtgg agacagtggt tctaaagggc
    13921 ttgcggatat tctcaagcca gctctctctc gtggagaatt gacagtgatt ggggcaacaa
    13981 ctcaagacga ataccgtaac accatcttga agaatgctgc tcttgctcgt cgtttcaacg
    14041 aagtgaaggt caatgctcct tcagcagaga atacttttaa aattcttcaa ggcattcgtg
    14101 acctctatca acaacaccac aatgtcatct tgccagacga agtcttgaaa gcagcggtgg
    14161 attattctgt tcaatacatt cctcaacgta gcttgccaga taaggctatt gaccttgtcg
    14221 atgtaacggc tgctcacttg gcggctcaac atccagtaac agatgtgcat gctgttgaac
    14281 gagaaatcga aacggaaaaa gacaagcaag aaaaagcagt tgaagcagaa gattttgaag
    14341 cagctctaaa ctataaaaca cgcattgcag aattggaaaa gaaaatcgaa aaccacacag
    14401 aagatatgaa agtgactgca agtgtcaacg atgtggctga atctgtggaa cgaatgacag
    14461 gtatcccagt atcgcaaatg ggagcttcag atatcgaacg tttgaaagat atggctcatc
    14521 gcttgcaaga caaggtgatt ggtcaagata aggccgtaga agctgtagct cgtgctatcc
    14581 gtcgtaaccg tgctggtttt gatgaaggaa atcgcccaat cggcagcttc ctctttgtag
    14641 ggtctactgg ggttggtaag acggagcttg ctaagcaatt ggcactcgat atgtttggaa
    14701 cccaggatgc gattatccgt ttggatatgt ctgaatacag tgaccgcaca gctgtttcta
    14761 agctaattgg tacaacagca ggctatgtgg gttatgatga caatagcaat accttaacag
    14821 aacgtgttcg tcgcaatcca tactctatca ttctcttgga tgaaattgaa aaggctgatc
    14881 ctcaagttat tacccttctc ctccaagttc tagatgatgg tcgtttgaca gatggtcaag
    14941 gaaatacagt aaacttcaag aacactgtca ttattgcgac ctcaaatgct ggatttggct
    15001 atgaagccaa cttgacagaa gatgcggata aaccagaatt gatggaccgt ttgaaaccct
    15061 tcttccgtcc agaattcctc aaccgcttta atgcagtcat cgagttttca cacttgacta
    15121 aggaagacct ttctaagatt gtagatttga tgttggctga agttaaccaa accttggcta
    15181 agaaagacat tgacttggta gtcagtcaag cggctaaaga ttatatcaca gaagaaggtt
    15241 acgacgaagt catgggggtt cgtcctctcc gtcgcgtggt tgaacaagaa attcgtgata
    15301 aggtgacaga cttccacttg gatcatttag atgctaaaca tctggaagca gatatggaag
    15361 atggcgtttt ggttattcgt gagaaagcct aagacagaat tttgagaata aaaaagaagg
    15421 agccagctga aaaaaactgg ttccttttga ggtacgacgg gcatgtcgtg tagtagagat
    15481 gtactattct agtttcaatc tactatagta gctcagaaat cggtacttaa acgtgctata
    15541 tcaaaaccag tccttgaaaa acgtggactg gtttcgtgtt tggattatta ctttgaacga
    15601 catgcgttaa aagttagttg aaccgccgta tgccgaacgg tacgtacggt ggtgtgagag
    15661 gggctagaga ttatccccta ctcgatttta aatcacatga cgttcaaagg catcatctga
    15721 aatcccttgt tccaagatga gttttgccca ttctttagca gagaagaggc tgtggtcctt
    15781 gtagtttccg caagattcga tggttgtccc tgggacatct tcccaagtag tagtttcagc
    15841 gatttccttg agcgaatcct tgataacagc tgcgatttta gcactggtgt gacgtcccca
    15901 cataatcatg tggaagcctg tgcggcaacc aaatggcgaa cagtcaatca tgccgtcaat
    15961 gcgggtacgg atgagtttgg ctaagaggtg ctcgatagtg tgaaggccgg cggtagggat
    16021 agagtcttcg tttggttgca ccaagcgaat atcataattg gagatgatgt ctccttttgg
    16081 tcctgtttct tccccaatca agcgaacata gggtgctttg acaatggtgt ggtcaagttc
    16141 aaaactttcg acaataactt cttttgacat ggtaaatcct ttcagttttc ttctctcatt
    16201 atatcataaa ggttgctcct gagacagaga gaaaacctct ccgaggctgg agaggttgaa
    16261 atctttactt acgatataag cggtcgtatt ggtagtatgg gtcaaaggtt acgttgatac
    16321 ccagtttacg aaggacattc ttgtcttcat cagtcaagat gatggttgag tgggcttcgc
    16381 ttcctttgag gttgccgagt tcttccatag cgcgggtagc atcaggattt tctgtagctg
    16441 tgatagcaag tgcaatcagg atttcatttg aatgaaggcg tggattgcgg ctaccgagat
    16501 gatcgatttt aagaccttgg attggcttaa caacttccgg ctcgattaat tttacttctt
    16561 tagcgatgtc agctgatttt ttgatggcgt tgatcaaggc agcggctgta gggccaaaga
    16621 gttctgagtt cttaccagtg acgatttccc catttggcaa ttcaaaggct agggctggtc
    16681 caccagtttc ttctgctttt tggcgcgcaa cgacagcaac cttacggtct gcaggtgtga
    16741 taccgaggtc gttcatgagc aactcaattt tcttgacggc agcttcgcca actttttcag
    16801 ctttgaagtc aagaactgtt tgatagtaac ggcggatgat ttcttgttta gaagcttcga
    16861 cagcggcctc gtcatctgta atagcgaaac caaccatgtt gacacccata tctgtcggtg
    16921 aagcgtatgg tgattttccg agaatacgtt ccaacatgcg tttgagcact gggaagattt
    16981 cgatatcacg gttgtagttg acagtggttt ctccataggt ttggagatgg aaggggtcaa
    17041 tcatgttgac atcatcaagg tcagctgtgg cagcttcata agccaagtta actggatgat
    17101 gaaggggaag attccaaaca gggaaggttt caaatttagc gtagccagat ttgatgccat
    17161 tgatttggtc gtggtacata ttggacatac acgttgccaa ttttccagaa ccaggtccag
    17221 gagcggttac gacaatcaag ttgcgactgg ttttgatgta gtcgtttttg cccatgcctt
    17281 ctggggaaat gatgtgatcc atatccgtcg gatatccttt gattggataa tgaagatatg
    17341 aatcaattcc gtttttctca agttggttgc ggaaggcatc tgcagcgggt tggccagcgt
    17401 attgtgtaat gacaacggaa ccaacaaaaa tccccaattc attgaatttg tcaatcaaac
    17461 gaagaacttc ttggtcataa gaaatgccta agtcgccacg tgctttggaa tgttcaatgt
    17521 tgctagcatt aatggcaatc acaacctcaa cctgctcttt caattcttgc aagagcttga
    17581 ttttgttgtc aggttcataa ccaggaagga cacgagcagc gtggaaatct tctaacattt
    17641 taccgccaaa ctctaagtag agcttgccgt caaattggtt aatacgctcc aaaatatggt
    17701 cgcgttgtaa attcaaatat tgttcagaac taaaagcttg ttttttcatt tttttacctc
    17761 tggactctat tataataaaa aattggaagt taggaaacta cggagctaaa aaagaaatta
    17821 aaaagattaa gcaaacgctt gcacaaaatt ttaaaaagtg ctatcataga ctatagatta
    17881 ttaaaataat gaggtaaaca gatgcaagaa aaatggtggc ataatgccgt agtctatcaa
    17941 gtctatccaa agagttttat ggatagtaat ggagatggag ttggtgattt gccaggtatt
    18001 accagtaagt tggactatct agccaagcta ggaatcacag caatttggct ttctcccgtt
    18061 tatgacagcc ctatggatga taatggttac gatattgctg attatcaagc gattgcaacg
    18121 atttttggaa ccatggagga tatggatcaa ctgattgcag aagctaagaa gcgtgatatc
    18181 cgtatcatca tggacttggt ggtcaatcat acctcggatg agcatgcctg gtttgtagag
    18241 gcctgtgaaa atcctaatag ccctgagcga gactactata tctggcgcga tgaacccaat
    18301 gacctagatt ctatctttag tgggtctgct tgggaatacg atgaaaagtc aggtcaatac
    18361 tatctccact ttttcagcaa gaaacagccg gatctcaact gggaaaatga aaaacttcgc
    18421 cagaaaattt atgagatgat gaacttctgg attgataaag gtattggtgg tttccgtatg
    18481 gatgttattg acatgattgg caaaattcct gacgagaagg tagtcaataa tggtcctatg
    18541 ctccatccct atctcaagga aatgaatcag gcgacctttg gagataagga tctcttgaca
    18601 gtaggggaga cttggggagc aacgccagag attgccaagc tctactctga tccaaagggg
    18661 caagaattgt ctatggtctt ccagtttgaa catatcggtc ttcagtatca ggaaggtcag
    18721 cctaaatggc actatcaaaa agagctgaat atcgctaagt taaaagaaat cttcaacaaa
    18781 tggcagacag agttaggagt tgaggacggc tggaattccc tcttctggaa caaccatgac
    18841 ctccctcgta ttgtctcaat atggggaaat gaccaagaat accgcgaaaa atctgccaaa
    18901 gcctttgcaa tcttgcttca tcttatgaga ggaactcctt atatctacca aggtgaggag
    18961 attgggatga ccaactatcc gtttgaaaca ctagatcaag tagaagatat tgaatctctc
    19021 aactatgcgc gtgaggctct tgaaaaaggt gttccgattg aagaaatcat ggacagtatc
    19081 cgtgttattg gacgtgacaa tgcccgtacc cctatgcaat gggacgagag caaaaacgct
    19141 ggtttctcaa caggtcaacc ttggttggcg gttaatccaa attacgagat gatcaacgtc
    19201 caagaagcgc tggcaaatcc agattctatt ttctatacct atcagaaact ggtccaaatt
    19261 cgcaaggaga atagctggct agttcgagct gactttgaat tgcttgatac ggctgataag
    19321 gtctttgctt atatacgtaa ggatggcgac cgtcgcttcc tagttgtggc taacttgtcc
    19381 aatgaagagc aagacttgac agtagaagga aaagtcaaat ctgtcttgat tgaaaacacc
    19441 ctagctcaag aagtctttga aaaacaaatc ttagttccat gggatgcttt ctgtgtggaa
    19501 atgactgact agaatgagca aacctcaagt ttttgaagct tgaggttttt tactatagtg
    19561 gattgaaact agaatagtgc acctctgctt ctaaaacatt gttagaaatc gatttgactg
    19621 tcccgatcga tttgtcctat tcttatttca ttttgctata cttgtagttg aggagaatta
    19681 agctcctcac tagtaaactc ttcataatcc tttttatttt tatgaagata ttgtttgaaa
    19741 gatgtgagtt tccacggatg ggtttgtgga gggatatact tgcgtctttc tttttttgtt
    19801 ctggttcttg ttcaaagttt ttcgaataga gttcatgatt tagtagctcc tttgtgtgat
    19861 agattttgtc agcgatattg aggtagatgt ctccgtcaaa tgcttttata actaatgctt
    19921 tcgtctttct gatgaaatag acttcttttc cttgttcggt agggatatag taacgatttt
    19981 ggaatcggat atggtgtcca ctatcgacga ctctctccgc cagtctagcc agaatgagat
    20041 tcctttcaga ggggttagga acctcctcga agacagagag ttttgtcttg tttccaaact
    20101 gttcattaaa ggtttgaatg taggaaagca ggaaggtatt ggcttcttcc aaggtatgaa
    20161 tattgttttg ttccagttcg ataggcaggc gagattgtag tgtctgattg agtctttcga
    20221 ctctcccttt agcttgaggg atagaggttg tctcaaggag aatccctagt tggtgacagg
    20281 cgtatccaaa ctgtgtatgg gtatcgtcct ccattttctt agagttggag gcttgatagg
    20341 taaagaccgt tctcttatct gttttaattt gaaggggaat gccgtgattg gctaagattt
    20401 gttcgaggac atgatagtaa gcattcaagt tctcttgttt atcaaaataa gcgcctagga
    20461 tattgccaga agcatcatca atggctaagt gtaagttaga tgtttgggct ccaaactagg
    20521 catgagggct ggcatccatt tgaatgagtt caccagcaaa tttctttctg ggtctactag
    20581 gatgtacttt tttagggtct tcaaggaagt tttcagccgt cggtaagatt ggattgtcta
    20641 ggggttgatt caggttcagt ttagcttgtt ttcttactct cttctttgtc tttctatggg
    20701 acttaggcga caggatattt ttcttataga gtatttttct aacagtagta tcagagagct
    20761 gaattccttc ttcttcagct agcaattcac agaaatgaag gacatttggt ttatatgttt
    20821 cataggagag gtattttttt aggagacgtt ctttgatttc atcagggatt gcatgttttg
    20881 gttttcgatt tctgtttccg tgtctgaagg cttcttttcc tttcagttga taggctagta
    20941 gcagacgatt gatttgtctt tcagaaagat tgagctcgac acaggctcgt ttctttgttt
    21001 tctttccttg ggctatagct tttatcacaa gatatttttt cgtttcattc atattcagtt
    21061 ggatcctttt catatgacta ttctaccaaa tgggacattt tcacgttcga tttactaaag
    21121 acattatcac attcgaatta cacaagatgc agatagtgaa aataaaggtg tagacattac
    21181 cgtaaaaaag tgatataatt gtatgatgtt caatgtatag gtgttaatca tgagtagacg
    21241 ttttaaaaaa tcaggttcac agaaagtgaa gcgaagtgtt aatatcgttt tgctgactat
    21301 ttatttattg ttagtttgtt ttttattgtt cttaatcttt aagtacaata tccttgcttt
    21361 tagatatctt aatctagtgg taactgcgtt agtcctacta gttgccttag tagggctact
    21421 cttgattatc tataaaaaag ctgaaaagtt tactattttt ctgttggtgt tctctatcct
    21481 tgtcagctct gtgtcgcttt ttgcagtaca gcagtttgtt ggactgacca atcgtttaaa
    21541 tgcgacttcg aattactcag aatattcaat cagtgtcgct gttttagcag atagtgagat
    21601 cgaaaatgtt acgcaactga cgagtgtgac agcaccgact gggactgata atgaaaatat
    21661 tcaaaaacta ctagctgata tcaagtcaag tcagaatacc gatttgacgg tcaaccagag
    21721 ttcgtcttac ttggcagctt acaagagttt gattgcaggg gagactaagg ccattgtcct
    21781 aaatagtgtc tttgaaaata tcatcgagtc agagtatcca gactacgcat cgaagataaa
    21841 aaagatttat accaagggat tcactaaaaa agtagaagct cctaagacgt ctaagaatca
    21901 gtctttcaat atctatgtta gtggaattga cacctatggt cctattagtt cggtgtcgcg
    21961 atcagatgtc aatatcctga tgactgtcaa tcgagatacc aagaaaatcc tcttgaccac
    22021 aacgccacgt gatgcctatg taccaatcgc agatggtgga aataatcaaa aagataaatt
    22081 aacccatgcg ggcatttatg gagttgattc gtccattcat accctagaga acctttatgg
    22141 tgtagatatt aattattatg ttcgtttgaa ttttacctca tttttgaaat tgattgactt
    22201 attgggaggg gtagatgttc ataatgatca agagttttca gctctacata ggaagttcct
    22261 tttcccagta gggaatgtcc atctagactc tgagcaggct ctaggttttg tacgtgaacg
    22321 ctactcacta gccgatggag accgtgaccg tggtcgcaac caacaaaagg tgattgtggc
    22381 tattcttcaa aaattaacgt caaccgaagc actgaaaaat tatagtacga tcattaatag
    22441 cttgcaagat tctatccaaa caaatatgcc acttgagact atgataaatt tggtcaatgc
    22501 tcagttagaa agtggtggaa cttacaaagt gaattctcaa gatttaaaag ggacagatcg
    22561 gatggatctt ccttcttatg caatgcctga cagtaacctc tatgtgatgg aaatagatga
    22621 tagtagttta gctgtagtta aagcagctat acaggatgtg atggagggta gatgaaatga
    22681 tagacatcca ttcgcatatc gtttttgatg tagatgacgg tcccaagtca atagaggaaa
    22741 gcaaggcact tttaagagaa gcttataatc aaggagttcg aatgattgtg tctacttcgc
    22801 atcgtcgaaa agggatgttt gaaactccgg aagagaagat agcagaaaac tttcttcagg
    22861 ttcgggaaat tgcaaaagaa gtagcagatg atttagtcat agcttatggc gcagagatat
    22921 actatactct ggatgctcta gaaaagctag aaaaaaaaga aattcctacc cttaatgata
    22981 gtcgttatgc tttgattgag tttagcatgc atacttccta tcgtgagatt catgcgggat
    23041 tgagcaatat tttgatgttg ggaatcacgc cagtaattgc tcatattgaa cgttatgatg
    23101 ccttagagaa taacgaaaaa cgtgttcgtg aactgattga tatggggtgc tatactcaga
    23161 taaatagtta tcatgtttta aaacctaagt tctttggtga aaaatataaa ttcatgaaaa
    23221 agagagctcg gtattttttg gaacgtgatt tagttcatgt agttgcaagt gacatgcaca
    23281 atttagacag tagacctcca tatatgcaac aggcatatga tatcattgct aagaaatatg
    23341 gagcgaaaaa agcgaaagaa ttttttgtag ataatcccag aaaaattata atggatcaat
    23401 taatttagga gaaaatatga aggaacaaaa cactttggaa atcgatgtat tgcaactatt
    23461 cagggcttta tggaaaagaa agttggtcat tttattagtg gcaattataa cttcttcagt
    23521 tgcttttgcc tacagtactt ttgttatcaa acctgagttt actagtacga ctcggattta
    23581 tgtagttaac cgtaatcagg aagagaagtc tggtttaacc aatcaagact tgcaggcagg
    23641 atcatacttg gttaaagact atcgtgaaat tatcctatcg caggatattt tggaggaagt
    23701 tatttctgat ttgaaactag atttgacgcc aaaaggtttg gctaataaaa ttaaagtaac
    23761 agtaccagtt gatacccgta ttgtctctgt ctcagttaat gatcgagttc ctgaagaggc
    23821 aagccgtatc gctaactctt tgagagaagt agctgctcaa aaaattatca gtattactcg
    23881 tgtttctgat gtgacaacac tggaggaggc aagaccggcg atatcaccat cttcgccaaa
    23941 tattaaacgc aatacactaa ttggtttttt ggcagggggg attggaacta gtgttatagt
    24001 tcttcttctt gaacttttgg acactcatgt gaaacgtccg gaagatatcg aagatacact
    24061 gcagatgaca cttttgggag ttgtaccaaa cttgagtaag ttgaaatagg agagaggaat
    24121 gccgacatta gaaatagcac aaaaaaaact ggagttcatt aagaaggcag aagaatatta
    24181 caatgccttg tgtacaaata tacagttgag cggagataaa ctaaaagtaa tttccgttac
    24241 ttctgttaac cctggggaag gaaaaacaac tacttccgta aatatagcaa ggtcgtttgc
    24301 gcgtacaggc tataaaactc ttttgatcga tggcgatact cgaaattcag ttatatcagg
    24361 agtttttaaa tcgcgtgaaa aaattacagg gctaacagaa tttttatctg ggacagctga
    24421 tttatctcac ggtttatgtg atacaaatat tgaaaattta tttgtaattc aatcgggatc
    24481 tgtatcacca aaccctacag ccttgttaca aagtaaaaat tttaatgata tgattgaaac
    24541 attgcgtaaa tattttgatt atatcattgt tgatacagca cctattggaa ttgttattga
    24601 tgcggcaatt atcactcaaa agtgtgatgc gtccatcttg gtaacagcaa taggtgaggt
    24661 gaataaacgt gatgtccaaa aagcgaaaca acaattagaa caaacagaga aactgttcct
    24721 aggagttgtt ttaaataaat tggatatctc ggttgataag tatggagttt acggttccta
    24781 tggaaattat ggtaaaaaat aacttaggaa agattttatg gatgaaaaag gattgaaaat
    24841 ttttctagca gtaatacaga gtattattgt cattttattg gtttattttc ttagctttgt
    24901 tagagagaca gaacttgaac gttcttcgat ggttatacta taccttctcc acttttttgt
    24961 attctatttt agttcctatg gtaacaattt ttttaaaaga gggtacctag ttgagtttaa
    25021 tagtactata agatatattt ttttctttgc aatagctata agtgtattaa acttttttat
    25081 agcggaacgg tttagtatct ctagaagagg aatggtatac ttcttaactt tagaaggaat
    25141 atccttatac ttgttaaatt tcttagtaaa gaaatattgg aagcatgtgt tttttaatct
    25201 aaaaaatagc aagaaaattt tactgttaac agtaacgaaa aatatggaaa aagttcttga
    25261 taaattgcta gaatctgatg aactttcatg gaaattggta gcagtaagtg ttttggataa
    25321 atctgatttt caacatgata aaatacctgt aattgaaaag gaaaaaatta ttgaatttgc
    25381 aacgcatgaa gttgtggatg aggtgtttgt caatcttcca ggagagagct acgatattgg
    25441 agaaattatc tctaggtttg agacaatggg gatagatgta actgtaaatc ttaaagcatt
    25501 tgataagaat ttgggtcgca ataaacaaat tcatgagatg gtaggattga atgtagtcac
    25561 tttctctaca aatttttata aaactagtca tgtgatttca aagagaattc tcgatatttg
    25621 tggtgccact attggcctta ttctttttgc tatagctagt ctagttttag ttccattgat
    25681 tcgtaaagat ggcggatcag ctatttttgc tcaaactcgt atagggaaaa atggtcgaca
    25741 ttttaccttt tataaattcc gttcgatgcg aatcgatgct gaagctatca aagaacagtt
    25801 gatggatcaa aatacgatgc aaggtggtat gtttaagata gacaatgatc ctcgtgttac
    25861 aaaaattggt cgctttattc gtaaaactag tttagatgaa ttgccgcagt tttggaatgt
    25921 ctttatagga gatatgagtt tggtgggaac acgtccacct acagtagacg agtatgatca
    25981 gtatactcca gaacagaaac gtcgactcag ctttaaacct ggtattacag gtttatggca
    26041 ggttagcggc cgtagtaaaa taaccgattt tgacgatgtt gtaaaattag atgtggctta
    26101 tattgataat tggacaatct ggaaagatat tgaaattttg cttaaaactg ttaaagttgt
    26161 atttatgaga gatggagcga agtaattcat atgaatgaga gaatgcaaat attaggagtt
    26221 actatagatc cattaacgat gaaagaaaca gtggatgctg ttgaacagta tgttttaaag
    26281 aagcatcctt tgcacttgat gggagttaac gcagataaaa ttaatcagtg ccatgaagat
    26341 gagaaaatca aaaaaatcgt taatgaatca ggaatcatta atgcggatgg agcatcagtt
    26401 gttcttgcaa gtaagttttt aggaacgcct gttcctgaac gagtagcggg tattgatttg
    26461 atgcaatgtc ttttagagtt gtcaaataaa aaaggatatt cagtttactt ttttggagct
    26521 aaagaagaaa ttttacaaga tatgctaaaa gtttttaaac aaagatatcc taatcttaat
    26581 gttgttggct atagaaacgg atatttttca cctgaagatg aaaaaaagat tcaggaagat
    26641 attaaaggag gaaaaccaga ttttgtattt gtagggatta cttctcctaa aaaggagtat
    26701 atcatccaat cattcatgga taatgggatt aatgctgtct ttatgggtgt tggtggcagt
    26761 tttgatgtat tatcaggaca cattaaacga gctccattat ggatgcaaaa attgaatctg
    26821 gaatggttgt tccgtgtagt taatgaaccc aaacgccttt ttaagcgtta ttttataggg
    26881 aatgttactt ttattaagcg agttttagat gaaaagcgaa aatcaaaaaa ataatattct
    26941 acatatttct cgtacaatgg atattggtgg tgcagaacgt attgtatatc aattgagttc
    27001 tgatttgaaa gatgaatttg atagtgtcca tgtcgcttca acaggtggac tatgggagag
    27061 caaactttta tcaaaaggag ttcaacatca taaaatttta gatgttgaca gtaagaatcc
    27121 cctaactatg gtaaagatcc tttcaagttt ttatagaatt atcaaaaata atgatattac
    27181 cattgttcac actcatcatc ggatggctgc cttttatatt cgcttgttga aaatcattaa
    27241 tcctaagttg atacatgttt acactgcaca taatgtattt aaaaataaat taccattata
    27301 caaattttcc ttaaaaaaag cgtattgtgt agctgtaagt aaagcggtta atgataattt
    27361 gaaacatgat gtaggaatca gtgatagtac agtaatctat aatggggttg tttttgaaaa
    27421 aactgataag ctagttggtg aaattgtaaa ctataacgga atcaaattgg ggtgtattgc
    27481 taggttatca gagcaaaaag gattgaccta cctaattgat gcgatgtctt tagtgaaaca
    27541 caggaatatt acgttgttca ttgtcggaga tggagagctt cgagatgagc ttgaaaacaa
    27601 ggtgaaacaa ttaaatcttc aaaaatcagt gatattttta ggttatcgaa aagatattgt
    27661 tgaatgtatc aatagttttg attacttagt gtcatcatct ttatatgagg ggtttggtct
    27721 aaatgcaatt gaagcattta tgaaggggaa aacgatggtt tcatcagata tcccaggaat
    27781 aaatgaagta gtcaataaca aaaatgggat tcttgttcct gttaaggatg atgttgcctt
    27841 agcgagagcg attgaaaagc ttgcgactga caaaaaactt agagaaaaac tcgcttatca
    27901 agcaaaaaaa gattatgaga caaaatttaa ttattccttg tttttggata attatcggag
    27961 actttataga aaattaatgg gagaatcaaa atgaaaaaag tcatgttggt ttttgggaca
    28021 cgtccagaag ctattaaaat gtgtccttta gtaaatgaac tgaaacaaaa tgattcaatc
    28081 aagacacttg tgtgtgtaac tggtcaacat aaggaaatgt tagagcaggt tttagaggtg
    28141 ttcaaggttg tcccagatta tgatttgggt atcatgaaag caaatcagac cctatttacc
    28201 attacgacta gtatcttgga taaaattcag gcggttctag agaaagaaaa accagatctt
    28261 gttcttgttc atggagatac tacaacaaca tttgcgacag ctttagcagc attttatatg
    28321 ggaatcaaag tgggacacgt cgaagcaggt ctcagaacct ataatctcca aagtccattt
    28381 ccagaggaat tcaatcgcca gacaacttct atcattgccg actatcattt tgcgccgact
    28441 gaagttgcga aggaaaatct actaagagag gacagaaaaa atatctttgt gacgggaaat
    28501 acagtcattg atgctttgaa gacgactgtt caagataact accatcaccc aattttagaa
    28561 tgggcaaagg gtagtaagtt aatcatgcta acggctcatc gacgagaaaa tcttgggaaa
    28621 ccgatggaaa acatgtttaa tgctgttaat cgaattttaa acgaattcga agatgtaaaa
    28681 gttgtatatc ccatccataa aaatcctaag gttcgagaat tagcaagtaa agtttttggc
    28741 gataatgaac gaatgaaaat cattgaaccg ttagaggtta ttgattttca taattttatg
    28801 aatcaaagct atatgatttt gacagattct ggaggtgtac aggaagaagc accttcttta
    28861 ggaaaacctg tcttggtgat gcgtgataca acagagcgtc ctgagggggt cgttgctggc
    28921 acgttgaagt tggtaggaac agaagaagag aatatctata gcaacttcaa acttcttctt
    28981 gaagatgaaa cagaatataa caagatgagc aaagctagca acccttatgg agatggaatg
    29041 acttgtaaac ggattgttga tattattctg gaagtataaa aataattcaa ttatggatga
    29101 ggaaagaata aattagattg atgataaaaa gaaaaatata tataatctgt gtattactgt
    29161 cgtatttttt acctagtttt tttacagttg gatcaatggc gactttattt gctttgcttt
    29221 ctactttagt taagctattt gtaacttttg attatattcc caaagttctt ttacagcata
    29281 aagtaacact gattgatatt ctagttgttc tatttttatt ttttcaagca tttgcagctt
    29341 ttcaaagcca aacgttgtac cttaactatg ttggaggtca gtttttcctt ttaggactat
    29401 attcattttt gaaacacttt ttattgttgg attgtaaaac aacaataaaa agcctctttt
    29461 taacctttat cttgtttttg tgtgttcaag taataactca attgcttttt ccggtcggtt
    29521 tcgattcttt gcaccctaca ggagataata gactttactt tttaggaaga aagaacatag
    29581 ctaccccgta tatcattgtt ggattaggtg gtttttactt attaaataaa aaaatgaatg
    29641 agtttatatc actaaaggag attatttttt taggattgtt cggaatttta tcatttttaa
    29701 cacaatccag tacagcgatt atatgttatg ggctttttat tttcatacgt ctattgggat
    29761 taaaggaaaa tataggaaaa ctatattctt tagtcagtat ggctgtatat gtttgttttt
    29821 ctctttctat aatcttttca caaagtacaa ttttatcaac ttttacagcg attttttcca
    29881 aaaatgcaac tttttcagga cgtatcaata tttggcaatt agcgattcgt atttttgaag
    29941 agaatttttg gtttggacga ggcctcaacg ttaattttaa tgcttggaca aatgggatta
    30001 tcgttaattc agcacacaat accttattag atatacttgc tcgaactggt atatttccag
    30061 gtgttttatt tatagtgctt cttatgaatc tgtttcttgg aaaatataga atagaatcaa
    30121 aaacactgtt ggctatgtta gcctcattta tgatttatat tacaatggag acttcatcta
    30181 tgagcatatt gctgctaatt attgttcttt gtgtatattg gccacgtgga gaggagaagt
    30241 tgcatgagca agttacttaa taccatctat tatcgactat ttagattata taaaaaaatt
    30301 tatctacaag tttttagtaa aaaaacggtt gacatcttgg gtgaaaaggc taatttagaa
    30361 aatgaactaa ttgtttcgtt tacaacaatt ccaagtcgtc ttaattattt accaagtatg
    30421 attaaaagta ttttcaatca gacaattatc cctaaccgtt ttattatgta tgtttataaa
    30481 gatgaatttg aaggcattaa tttggagagt attctagaac ttgaaatcaa aaatggtttg
    30541 gaaattgtct atgtggatga gaatcttcgt tcacacaaaa aatattttta tgctatgaag
    30601 gataatccga acagtatagt tgttctagtt gatgacgata tcatttatcc tcgaaatact
    30661 ataaagaaac tgattgcatc ctatagaatt tatccacagt gtgtttcagc aatgcgatgt
    30721 catcgaatta agttgttttc tgatggaagt ttatatccat ataatcaatg ggaatatgaa
    30781 atatcaggag ctactatacc atcgtatttt aattttttta ctagcggagg tgggacatta
    30841 tttcctccat gtactcgcaa tgaggatctt tttaataaaa aaaatatcag ggaactcagt
    30901 tttctagctg atgatgtatg gttgaatttt ttggtagtca aaaatggaat taaaacagta
    30961 aaagcaacac gatataaagg gacaccatta actatagatg acaatcctga ggagagtttg
    31021 gtatatttga ataccgtata tgataacaac aatgataaat gtattagaaa tatggttgaa
    31081 tattatcaaa ttaattttac agaggataaa taatgaatgt tgaaaaaaat ttgaaacgtg
    31141 gaattttcta tactgcaata gggaagtatt cgaatgtagt tattcaatta cttgtaacag
    31201 caattcttag ccggattctc tcacctgtag aatatggtat cgtagcagta gtaaatgtat
    31261 ttcttttatt ttttcaaatg ttagcagatt caggaatagg acctgctatt gttcaaaata
    31321 aagaactgaa taagtcagat ttaatcagca ttttctcatt aacgatttat agtggaatcg
    31381 tactttcttg tatttttgct ttactaggat atcctatggg ggtgttatac ggcgaaacta
    31441 tttatgttag tttatttccg cttttaggtc tttgtgtttt attttatacc attacaattg
    31501 taccgcaagc tattctaatg aaaacgatga actttaaaat agttaatttt ctaactattt
    31561 tttctaacat tgctagtggc ttggtgggcg ttattctagc ggtatcacat tttggtgtct
    31621 attctctaat tttttctaat attgt
//
LOCUS       DAVLBE010000022        29188 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.022, whole genome shotgun sequence.
ACCESSION   DAVLBE010000022 DAVLBE010000000
VERSION     DAVLBE010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29188)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29188)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29188
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.022"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(64..1686)
                     /gene="groL"
                     /locus_tag="VXB91_001050"
     CDS             complement(64..1686)
                     /gene="groL"
                     /locus_tag="VXB91_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HEV0470521.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISHRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEATGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            complement(1702..1986)
                     /gene="groES"
                     /locus_tag="VXB91_001051"
     CDS             complement(1702..1986)
                     /gene="groES"
                     /locus_tag="VXB91_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HEV0470522.1"
                     /translation="MLKPLGDRLVLKVEEKEQTVGGFVLAGSAQEKTKTAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            complement(2142..2537)
                     /locus_tag="VXB91_001052"
     CDS             complement(2142..2537)
                     /locus_tag="VXB91_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEV0470523.1"
                     /translation="MYNKVILIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EVDFVNMVLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVTEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            complement(2615..3376)
                     /locus_tag="VXB91_001053"
     CDS             complement(2615..3376)
                     /locus_tag="VXB91_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HEV0470524.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEILKS
                     EFAVSFPNQTVWTFPLDVTDMVMVKTVCSDILETIGRIDILVNNAGLALDLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTRCFLPAMIKVNQGHIINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTSQPRRVQITDMTIMANQQATGFMVHKK"
     gene            complement(3418..4044)
                     /locus_tag="VXB91_001054"
     CDS             complement(3418..4044)
                     /locus_tag="VXB91_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HEV0470525.1"
                     /translation="MIFTYNKEHVGDVLMVIVKNSGDAKLNVERKGKVARVFLKENGE
                     TVAWNIFEVSSLFETAERGQVFLTDEQVARLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKTVQIVAGAPNARVGLKTIVALPGAMMPKGNLIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDSAKHWTA"
     gene            complement(4060..4377)
                     /locus_tag="VXB91_001055"
     CDS             complement(4060..4377)
                     /locus_tag="VXB91_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEV0470526.1"
                     /translation="MIQPASLEELASLVEKAGKKVFLFVADWCGDCRYIYPALPEIEE
                     TNPEFTFIRMDRDQYMDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKEQINDFLA
                     GLK"
     gene            complement(4374..4673)
                     /locus_tag="VXB91_001056"
     CDS             complement(4374..4673)
                     /locus_tag="VXB91_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HEV0470527.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDRKLMKTQEELTE
                     IVRDHFSDMGEIATLYVQVYESSLESLVGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            complement(4958..5149)
                     /locus_tag="VXB91_001057"
     CDS             complement(4958..5149)
                     /locus_tag="VXB91_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein"
                     /protein_id="HEV0470528.1"
                     /translation="MYYSVDDVVSNAFKKRMILDSFFAFNCSGTMKVSTWVYDKGEWY
                     YVSSSGSMIANDWVKDNGK"
     gene            complement(5310..5984)
                     /locus_tag="VXB91_001058"
     CDS             complement(5310..5984)
                     /locus_tag="VXB91_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0470529.1"
                     /translation="MKKKAFGIVLLVLAAWILLQGNFGIPSLDGKIWPLLGIVFFAYK
                     SIESILRRHLTSAVFTGLLALIIANYAYDLLPVTNHSLIWASILVVLGVGYLTHSSKF
                     WNEKKWWYNGKKTVVTDKEVAFGSGTFYKQDQDLVDDQVEVAFGDAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGAAKADAPVAPTSKTLIIRGDVAFGKL
                     EIVYVK"
     gene            complement(5990..6436)
                     /locus_tag="VXB91_001059"
     CDS             complement(5990..6436)
                     /locus_tag="VXB91_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0470530.1"
                     /translation="MKLRIEIDGNLEETEIVIKTPTLTDEIADLQRLLQESKAPRLTF
                     YKGTGEYYLDLSEILFFETEGSKIYAHNQKEAYEVRLKLYELESILPRYFNRVSKSTI
                     ANIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            complement(6550..7053)
                     /locus_tag="VXB91_001060"
     CDS             complement(6550..7053)
                     /locus_tag="VXB91_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEV0470531.1"
                     /translation="MKNYQEWYRNISSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVYVLIPASGFVTLSLFRKKINHPRPYETWDICPLLDKDSSGRSM
                     PSRHVFSATIISMACLHASLPIGLVCLIFSALLGLVRVLGGVHYPKDVLVGYACGLVW
                     GFLFFLF"
     gene            complement(7050..7412)
                     /locus_tag="VXB91_001061"
     CDS             complement(7050..7412)
                     /locus_tag="VXB91_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HEV0470532.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGKAESVHQVTSWLTGYEVS
                     DVLACLDRDVTYGDFFRQAPYYVPERIAITGKICGVRIEEIDDPLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            complement(7478..9337)
                     /locus_tag="VXB91_001062"
                     /pseudo
     CDS             complement(7478..9337)
                     /locus_tag="VXB91_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001850459.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
     gene            complement(9376..9825)
                     /locus_tag="VXB91_001063"
                     /pseudo
     CDS             complement(9376..9825)
                     /locus_tag="VXB91_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809294.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
     gene            complement(9949..10665)
                     /locus_tag="VXB91_001064"
     CDS             complement(9949..10665)
                     /locus_tag="VXB91_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV0470533.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            complement(11546..12961)
                     /gene="ply"
                     /locus_tag="VXB91_001065"
     CDS             complement(11546..12961)
                     /gene="ply"
                     /locus_tag="VXB91_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HEV0470534.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQ
                     LKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLKQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFEALIKGVKVAPQT
                     EWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTS
                     FLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWNELSYDHQGKEVL
                     TPKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRK
                     RTISIWGTTLYPQVEDKVEND"
     gene            complement(12972..13304)
                     /locus_tag="VXB91_001066"
     CDS             complement(12972..13304)
                     /locus_tag="VXB91_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0470535.1"
                     /translation="MYICIDNSMTKNKELVKNQTFKPALLTRRLVKNFMIEEPDLARN
                     PFTRPTLIDLDKVFMLDNTGIPTSYLARRRRNVSEELYEEILDYLVQPRLISLNKSEF
                     MQLNPGTY"
     gene            complement(13375..13983)
                     /locus_tag="VXB91_001067"
     CDS             complement(13375..13983)
                     /locus_tag="VXB91_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0470536.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSLLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            complement(13996..14454)
                     /locus_tag="VXB91_001068"
     CDS             complement(13996..14454)
                     /locus_tag="VXB91_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HEV0470537.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
     gene            14579..14978
                     /locus_tag="VXB91_001069"
                     /pseudo
     CDS             14579..14978
                     /locus_tag="VXB91_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(15743..16003)
                     /locus_tag="VXB91_001070"
     CDS             complement(15743..16003)
                     /locus_tag="VXB91_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0470538.1"
                     /translation="MRERSATGAQGLSKSIKKHLNDLTRLTASLLGDEKLSAITSSSA
                     VKADMHRFVIELEPVKSTILQNNDISLDQNEIFEILKNFFDG"
     gene            complement(16062..16613)
                     /locus_tag="VXB91_001071"
     CDS             complement(16062..16613)
                     /locus_tag="VXB91_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0470539.1"
                     /translation="MPANTKVIFQEMFADFQNYYVLIGGTATSIVLDSQGFKSRTTKD
                     YDMVIIDEVKNKEFYTTLNHFLELGEYQGSQKDEKAQLFRFTTTNSEFPSMIELFSIL
                     PEYPLKKDGREIPLYFDQDASLSALLLDEDYYNILVHLKETIQGYSVLSNCGLYSSKI
                     SSNHVSFHLQPQNSVLSSLQLAS"
     gene            complement(16603..17598)
                     /locus_tag="VXB91_001072"
     CDS             complement(16603..17598)
                     /locus_tag="VXB91_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0470540.1"
                     /translation="MNVKKIMSIFQSFYVDVSIEELTLTLPISFVKRFEYTQMTFHKE
                     SFLLIKEKRRGSLSSFVTQARTMGEKANMDVVLVFSKLSDSEKKQLLQARVPFVDFKG
                     NLFFPPLGLVLNANDTEVPKELTPSEQLTWIAFLLTKGQKVVDVDLLSQVTGLPNSTI
                     YRCLRTFKALYWLNKQNKLYTYTVSKKELFLKSVSCLFNPIKKRILLPDGDIKQIKSV
                     SNLLYGGAYALSHSTFLAETDENTSYVIWQRKFNQLSLPLSQHILKGKMLEIWKYRPF
                     VSEFWNDFKNNHDKQFVDPISLYLTLKDDDDPRIEEESEALENMILQYLGEDDAS"
     gene            complement(18006..18431)
                     /locus_tag="VXB91_001073"
     CDS             complement(18006..18431)
                     /locus_tag="VXB91_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000204059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0470541.1"
                     /translation="MTSRVFIDADCISVFLWVGTEHLLEKLYSGKIVIPQEVYDEINI
                     PTIPHLKSRIDQLVAKGSAEIVSIDIGTEEYALYRDLTRNHDSNKIIGKGEAASISLA
                     KKHNGILGSNNLRDVKSYVEEFSLEHMTTGDILIEAFKA"
     gene            complement(18575..18943)
                     /locus_tag="VXB91_001074"
     CDS             complement(18575..18943)
                     /locus_tag="VXB91_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0470542.1"
                     /translation="MYHLYYDEVKKSSVSLILIGEGDETERKADQFASYFLIFPSSLY
                     RMVEEIRENANRTHLEVEDIIKLGQFYGISHKVMLYRLRNDGYLDAEEIKNMDISVIE
                     TASRLGYDTSLYRPLSESKK"
     gene            complement(18965..19171)
                     /locus_tag="VXB91_001075"
     CDS             complement(18965..19171)
                     /locus_tag="VXB91_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0470543.1"
                     /translation="MDLSNKASNLRKKLGADGESPIDIFKLVQKIENLTLVFYGLGKN
                     ISGVCYKGTQFSLIAVNSDMSLGR"
     gene            complement(19158..19319)
                     /locus_tag="VXB91_001076"
     CDS             complement(19158..19319)
                     /locus_tag="VXB91_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0470544.1"
                     /translation="MYVINVCDVGKRIKELRISSNLTQDKIAEYLSLNQSMIAKMEKG
                     ERNITNGFK"
     gene            complement(19678..20634)
                     /gene="lytA"
                     /locus_tag="VXB91_001077"
     CDS             complement(19678..20634)
                     /gene="lytA"
                     /locus_tag="VXB91_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HEV0470545.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKYDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            complement(21010..22380)
                     /locus_tag="VXB91_001078"
     CDS             complement(21010..22380)
                     /locus_tag="VXB91_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEV0470546.1"
                     /translation="MNKKRTVDLIHGPILPSLLSFTFPILLSNIFQQLYNTADVLIVG
                     RFLGQESLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWIL
                     GALLSILVMLLGFLGLYPLLQYLDTPAEILPQSYQYISMIVTCVGVSFAYNLFAGLLR
                     SIGDSLAALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRK
                     SVPELLPQFKHFKWDKSLYADLLEQGLAMGLMSSIVSIGSVILQFSVNTFGAVIISAQ
                     TAARRIMTFALLPMTAISASMTTFASQNLGAKRPDRIVQGLRIGSRLSISWAVFVCIF
                     LFFASPALVSFLASSTDGYLIENGSLYLQISSAFYPILSLLLIYRNCLQGLGQKILPL
                     VSSFIELIGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHPLIKEGKAIL
                     ATKVQS"
     gene            complement(22687..23853)
                     /gene="recA"
                     /locus_tag="VXB91_001079"
     CDS             complement(22687..23853)
                     /gene="recA"
                     /locus_tag="VXB91_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HEV0470547.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVPLDLGDELEIEIEE"
     gene            complement(23908..25164)
                     /locus_tag="VXB91_001080"
     CDS             complement(23908..25164)
                     /locus_tag="VXB91_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HEV0470548.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGASSIFKGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQEQGTEVIKVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            complement(25249..26265)
                     /locus_tag="VXB91_001081"
     CDS             complement(25249..26265)
                     /locus_tag="VXB91_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEV0470549.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNVERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEEALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSVGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNILRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            complement(26273..26791)
                     /locus_tag="VXB91_001082"
     CDS             complement(26273..26791)
                     /locus_tag="VXB91_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0470550.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKIAGIVNITADQRKRVRHIGELFIVIGKRYWNNG
                     LGSLLLEEAIEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLIG"
     gene            complement(26781..27224)
                     /gene="tsaE"
                     /locus_tag="VXB91_001083"
     CDS             complement(26781..27224)
                     /gene="tsaE"
                     /locus_tag="VXB91_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HEV0470551.1"
                     /translation="MYTKNEEELQALGERLGHLLAKNDVLILTGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLLEELQYGV"
     gene            complement(27310..27930)
                     /locus_tag="VXB91_001084"
     CDS             complement(27310..27930)
                     /locus_tag="VXB91_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0470552.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTVFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            complement(28313..29176)
                     /locus_tag="VXB91_001085"
     CDS             complement(28313..29176)
                     /locus_tag="VXB91_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0470553.1"
                     /translation="MNTLAEKFRLKRKELRLSQQTLAEGICEQSQISKIERGHFIPSA
                     DLLFKLSQRLEVPLDYFFNEQIEVKSNLSNFKHLSARLLDDRNYDDLEYLYKIEVERS
                     TFLTLEDRTYLEWIKSIIDFYQYDSKCEAISSLENILLKVSSNTLIYLKALNTLSNFY
                     SLVGREQEYEANYSHLIELYQTKNLDHQEFLFGYIRVRYNYAHYLVSKEKYNEAIQEA
                     LETIELCKQRQTSYQLAPLLILVGNAGAKFLDREQVKNYYIEARELCKIYNNPLMLMK
                     IENYLKELDTV"
BASE COUNT         8762 a         6497 c         4989 g         8940 t
ORIGIN      
        1 taaaaagaag ggttagtcat tccctccttt tgtgtttttt ataagttgtt ttctatagaa
       61 agcttacatc atcccgccca tcatacttgg atccattgct ggagctgggg ctactggttc
      121 tggtttattg gctacgactg cttctgttgt caaaatcaag ctggctacag atgctgcatt
      181 ttgtagggct gaacgactca ctttaactgg atcaatgata ccttgatcaa tcatgttaac
      241 ccactcgcca gttgctgcgt taaatcctat accaagctca gcatttttca aacgatcgat
      301 aacgatagat ccttcaaatc ctgcattgtg agcaatttga cgaacgggtt cttccaaagc
      361 acggagaaca atattacgtc ctgttgcttc atctcctgtc aattccaagg tagcaacagc
      421 tggaatcaca ttggcaagag ctgttccacc gcctgcaaca ataccttctt caacagctgc
      481 acgagtagcg ttgagggcat cttcaatgcg gagtttcatt tctttcaact cagtttcagt
      541 tgcggctccg accttaataa ccgctacacc acctgacaat ttggccaagc gttcttgcaa
      601 tttttcacgg tcaaattcag aagttgtagt ttcgatttga gacttgataa ccgcaacacg
      661 gtgagaaatc gcttcaggat ttcctgcacc ttctacaata accgtgctat ctttgtccac
      721 ggtcactctc gctgcttgac caagagcttc aattgtcgca tctttcaact caagaccaag
      781 gtcttctgtg ataactgttc cgcctgttaa gatggcgata tcttcaagca tggctttgcg
      841 acggtcacca aaaccaggtg ccttgactgc tactacgttg aaggttccac gaatcttgtt
      901 caaaacaaga gttggaagag cctcgccatc cacatcatcc gcaataatca agagtggacg
      961 attgctttgg agaatgcttt ccaaaagtgg caagatctct tggatattgg aaattttctt
     1021 gtctgtaatc aaaatgtacg gattttcaag gtcagccacc attttttcgc tatctgtcac
     1081 catgtactgt gaaaggtaac cacggtcaaa ctgcattcct tctacgactt caagctctgt
     1141 ttccatacca cgtgactctt cgatggtgat gacaccgtct ttgccaactt tttccattgc
     1201 ttcagagatg tactcaccaa ctttttcaga acgagaagat acggctgcaa cttgagcgat
     1261 agcttcttta ttggcaacag ggatggcgtt gtttttcaaa gcttcaactg ctgcggcaac
     1321 tgctgtttca atcccacgac gaataccgat tggatttgca cctgctgtga cgtttttgat
     1381 tccttcacgg acgatagctt gggtcaagac tgttgcagtc gtagtcccgt cacctgcgat
     1441 atcattggtt ttagaagcta cttctgatac caatttggca cccatatttt caaaatggtc
     1501 ttctaattca atttctttgg caatagtcac accgtcattg gtaatcaatg gtgagccaaa
     1561 tgatttttca agaacgacat tgcgaccttt tggtcccaag gttactttaa cagtatctgc
     1621 aaggatatcg acaccacgga ccatagctga acgggcatct gatgaaaatt taatttcttt
     1681 tgacatactt actttctcct tctattcttc aatgattgcc aagatgttag cttcgcctac
     1741 gatgatatac ttttcatcgc catctttgac atcaagacct gcgtgggctt caactaagac
     1801 acggtctcca gttttaacac ttggagcaac caagtcaccg ttcaaggtac gaacaccttg
     1861 tccagtagcc acaacttggg ctgttttggt tttttcttgg gctgaacctg cgagaacaaa
     1921 gcctccaaca gtttgttctt tttcttctac ttttaagacc aaacggtccc ctaatggttt
     1981 caacatctga tttcctccat aatgagatag atattattag cactctttat acctgagtgc
     2041 taattcatag ttctattgta tcacttagtc agaaataatc aagaaaaaag tctgactttc
     2101 tcaagataaa aagcctgaga ccaactcaga ctttttaatt cttaaaatgg caattcttcc
     2161 tcttccaaga ccaaatctgc caaatcttgg cctgcattat tttcacgcat agcacgttgg
     2221 gcacgacttt ccaagagttg gaatcctgtc acaaggactt cggttacata attcatctga
     2281 ccatttttct caaagcgacg ggtacgcaat tctccatcaa cggaaatgag actacctttg
     2341 gttgcgtagc ttgccaaagt ttctgctagt ctgccccata ggaccatatt gacaaaatca
     2401 acttcacgtt caccgttttg gtctttgtaa cgacggttga cagcgatagt tgctcgcgct
     2461 actgacttgt cattgttggt tttgtgcaat tctggtgtag acgttaaacg tccaatcaag
     2521 ataactttat tatacatatt ttcttcctcc tacttatcta ttcgtaggaa atcaaaaaaa
     2581 gttacagaaa tttgtaactt ttcgagaaaa ttttttattt tttatgaacc atgaaacctg
     2641 tcgcctgttg attggccata atggtcatat ctgtaatctg aacacgacga ggttgactag
     2701 tcacatagac tactgtatct gcaatatcct gagcttgcaa agcttctatt ccttggtaaa
     2761 cggacgcagc tcgttcttta tcaccatgaa aacgcactgt agaaaaatct gtttcgacaa
     2821 ttccaggctg aatggttgtc accttgatat ccgttgcgat ggtatcaatt cgcagtccat
     2881 ccgaaaaggt cttaaccgca gccttggtag ctgagtaaac agcggcacca gcataggcgt
     2941 agattcctgc ggttgacccc atattgataa tatgaccttg attgactttt atcattgctg
     3001 gcaagaaaca gcgagtaacc gccatcagac ctttaacatt ggtatccaac atggtcaaca
     3061 tatccaactc ctcatagtct tgatagggag ccaagtcaag agccagtccg gcgttgttga
     3121 ccaagatatc aatcctccct atcgtttcta gaatatcaga gcaaacagtc ttcaccatga
     3181 ccatatccgt cacatctagt ggaaaagtcc agacggtttg atttggaaag cttactgcaa
     3241 actccgactt gaggatttct aatctgtcta tccgtcgtcc tgttagaacg acatcctcac
     3301 cctgctccag ataagcacgc gcaatcgctt caccgattcc tgaggttgct cccgtaatca
     3361 caacattttt tgccatctta tttccttcta gctggtctat cagatattaa caacttctta
     3421 ggcagtccag tgtttagctg agtcaaatgg tgttccgaca acttggtctt ctgataattc
     3481 aagcacccca cgtttttgtg gagcatttgg cagatgcaat tcacgaggac tgcacatcat
     3541 accaaaactc ttttcaccac gaagttcacc tgggaaaatg agattccctt ttggcatcat
     3601 agctccagga agcgcgacaa tggttttcaa ccccacacgc gcattgggag ctcctgcaac
     3661 gatttgtaca gtcttatcac ttgcgactgc aacttggcag atgttgaggt ggtcactatc
     3721 tggatgggct accatctcaa caatttcacc gacaacaaac ttaggttcct tatcattaac
     3781 aatttcttct gtaaaacctt ccgcctgcaa ctcttggttc aaacgagcga cttgctcatc
     3841 tgtcaaaaag acttgaccgc gctctgcagt ttcaaataaa cttgaaactt cgaaaatatt
     3901 ccaagccact gtttccccat tttctttgag gaaaacacgg gctaccttgc ctttgcgttc
     3961 cacattcagt ttggcatctc cgctattttt cacgatgacc ataaggacat caccgacatg
     4021 ttctttgtta tacgtaaaaa tcattgtttc ctttttctcc tatttcaatc ctgctaaaaa
     4081 atcgttaatt tgctccttac ttttacggtc gcgattgaca aaacgaccga tttccttgtc
     4141 cttttctaga acaacaaggc taggaattcc gtaaacatcc cagagtttgg ccaaatccat
     4201 atactgatct cggtccattc gaataaaggt gaactctgga ttggtctctt caatctctgg
     4261 taaggcagga taaatataac gacaatcgcc acaccagtct gccacaaaaa ggaagacctt
     4321 cttgcccgct ttttccacta aagatgctaa ttcttctaaa cttgctggct gtatcataag
     4381 acttcctcct catagactag gtcttcattt tcatagacaa aggtataatg acggccatcc
     4441 tcaaaaatga cgccaccaac caagctctcc agactgcttt cgtaaacttg aacataaagg
     4501 gtcgcaattt cccccatgtc ggaaaaatgg tctcgcacaa tctctgtcaa ctcttcctga
     4561 gtcttcatga gcttacggtc atctgcaact tttttcgtag caagggcaag gcttccgata
     4621 cctagcagag ccaagcctgc catccacatt tttttagctt tcataccatt cattttaaca
     4681 caaaaaaggc ttcaggacaa atgaggaagc agcagaaaag caagtaaaaa gcctcttcct
     4741 ttaaggaaaa ggacttctta tactaagagc aaactagaaa gctagccgca ggctgctcaa
     4801 aacacggttt tgaggttgta gataaggcga cgttgacgtg gtttgaagag attttcaaag
     4861 agtattattc ttattgccag gcacctaagt tgccaacgta gtaaccatca ggtgtgtagg
     4921 tattgcgaag catcttacct gatgaagcca gataatacta cttgccattg tctttgaccc
     4981 aatcattcgc aatcatggaa ccagaagaac ttacataata ccattctccc ttgtcataaa
     5041 cccaagtact gactttcatg gttcctgagc aattaaaggc aaaaaaactg tccaatatca
     5101 ttcgtttttt aaaagcattc gacactacat catctacgct gtagtacata gatacatcaa
     5161 acgtaaaagc caaaatatcg aaaaatatac aacttttaaa ggcagcattt cattttttaa
     5221 agtctaacaa ccatagaact gaaatcagag caaggcatca atttcctact ctatagtacg
     5281 cctattttga tggttgaagt gaagattttt tatttaacgt agacaatttc caacttccca
     5341 aaagccacat ctccacggat aatcaaggtt ttgctggttg gggctacagg agcgtcagcc
     5401 ttagctgcac caaaggaggt ttctactttc aaatctacac gccagtgttg tggaacatag
     5461 acggttgcat ttccgaaggc tacttcaata tttaaagttg caaaatcacc tagcatctct
     5521 gcattatcat agtagatttt agcatcccca aaagcgactt ccacttggtc atctacgaga
     5581 tcttgatctt gcttatagaa ggtcccgcta ccaaaagcga cttccttatc cgtgacgact
     5641 gtttttttcc cattgtacca ccattttttt tcattccaga acttacttga atgcgtcaga
     5701 taaccaacac caagtaccac caagatgcta gcccaaataa gagaatgatt ggtaactggt
     5761 aacaagtcat aagcgtaatt tgcaatgatg agcgccagta aacctgtaaa aactgccgaa
     5821 gtgagatgac gtctaaggat ggactcaatg gacttataag caaaaaaaac aatacctagt
     5881 aaaggccata ttttaccatc caaagaagga attccaaaat tcccttgcag caagatccaa
     5941 gctgctaaaa ccaataaaac aataccaaat gctttctttt tcatgttttt tacctcatgt
     6001 ttcttagatt ttcttttagg agggattggt aatgccgtga gacatgaacc tccttgtgcg
     6061 tctgataaaa ggaaatggtg cccgttcctg aaaaggactt gtccactgag taaatctgac
     6121 ggatgtttgc gatcgttgac ttggaaactc gattaaaata gcgaggcaag atagactcca
     6181 actcatagag cttgaggcga acctcataag cttccttctg gttatgagcg tagatcttgc
     6241 tcccttctgt ttcaaagaag agaatttctg acaggtctag ataatattca cctgtcccct
     6301 tgtaaaaagt caacctcgga gcctttgact cttgcaagag ccgttgcaag tctgcaattt
     6361 catctgtcaa agtgggggtc ttgatgacaa tttcagtctc ctctaaattg ccgtcaatct
     6421 caattcgtaa cttcatcaca tctcctttct gactctacta tatcaaagct aagttaggaa
     6481 tacaagggca aaaaagcaag tggtcaattt gaagcagtaa gtggttgtag gactagctta
     6541 acttacatgt cagaatagga agaaaaggaa tccccacacc aaaccacaag catagccaac
     6601 caagacatcc ttgggataat gaacaccccc taaaaccctc accaacccca gcaaagctga
     6661 aaagatcaag catactaagc caataggtag actagcatgc agacaggcca tggagatgat
     6721 agttgccgaa aagacatggc gactgggcat cgaccgtccc gaactatcct tatcaagaag
     6781 gggacagata tcccaagttt cataaggtct cgggtgattg attttcttac gaaacaggga
     6841 caaggtcaca aaacctgatg caggaataag cacataaacc ccaacttgct gaccaagtcc
     6901 tagttgcagg taagtggtga ctagcaagat cagatagacc aggggcatgg cgactgtcat
     6961 caaacgattg aaactgcgta ataggaataa aagaattgga cgactagtta gtctggagct
     7021 gatatttcga taccattctt gataattttt catttatgct tctcatactt ttctagaact
     7081 tgttgagatg ttttcccctt ggcaagccaa tccactagct tgtccaagcg acgtatttcc
     7141 tgcatcagag gatcatcaat ttcctcaata cggacaccgc aaatcttccc tgtaattgca
     7201 attcgttcag ggacataata tggtgcttgt ctaaaaaaat ctccgtaagt aacatcccta
     7261 tccagacaag caagaacatc actcacttca taccctgtca accaactggt cacttggtga
     7321 actgactctg cctttccacc ctttcgctca acttttgcaa tcaaggctaa gtagacagca
     7381 gcaaatttca tattgtataa tttctgactc atacttctct ctttctatgt gtactagtat
     7441 aaataagaaa aagaaggccg tcaagccttc ttttgattta ttcttctgct tcatcttctg
     7501 taaattgact attgtacaag tcagcgtaga agccaccttg cgccatcagt tcctcatagt
     7561 tgccttgctc gatgatattt ccatctttca tgaccaagat caagtctgca tttcggatgg
     7621 ttgacaagcg gtgggcaatg acaaaggatg tgcgtcattc catcaaacgg tccatggctt
     7681 tttggatcaa ttcctctgtc cgtgtgtcaa cagaagaagt cgcctcatcc aaaatcaaaa
     7741 gcggtgcatc cttaagaagg gcacgagcaa tagtcaatag ttgtttttgt cctacagaca
     7801 aggtcacggt gtcatccaag atggtatcat agccatctgg caaggtcata ataaagtggt
     7861 gaattcccac agccttacta gcttccatca ttcgttcatc actaatccct atttgattat
     7921 agatgagatt gtctcgaata gttccttcaa agagccaggt atcctgcaag accattgaaa
     7981 aggcatcatg cacttctgaa cgcgtcatag ccttggtatc cacaccatca atgtgaatac
     8041 ttcccttatc aatctcatag aatttcatca aaagattgac aatggttgtc ttaccagtcc
     8101 cagtcggccc aacaatggca accttttgac cagcatgagc tgtcgcagag aagtcatagt
     8161 cttgaacatt gacaccgtcc accagaattt ctcctgctga cacgtcgtag aaacgtggaa
     8221 tcagattgac cagagttgat ttaccagaac ctgttgaccc aataaaggcc actgtttgac
     8281 cagtttctgc tttaaagcta acatgttcaa taactgcctc cgaatttgcc gcatagcgga
     8341 aggtcacatc cttaaactcg acctgacctt tgaagttttc atcagtcagc tgcacttgaa
     8401 cagggttttg gatagaagaa tgcaaatcta aaacttgatt aatccgctta gcagagacca
     8461 tagttcgggg aagaacgatg aagagtgctc ccatgagaag gaagcccatg acaacctaca
     8521 tggcataaga catgaaaaca atcatgtcac taaagagagg cagacgcgct atcgaagcag
     8581 cgtcgttaat cacataggcc ccaatccagt aaatcgctac actcaaacca cttgaaatcc
     8641 ccatcatgat aggattcaaa atagccataa gacggttgac aaacaaattc aaacgggtca
     8701 attcatcatt tactgctgca aatttttcat tttgataatc ctctgcatta taggcacgaa
     8761 cgacacgaat acctgttaaa ctctcacgag tgatactgtt cagtttatct gtcaacccct
     8821 gaatcaagga ctgttttgga aaggctagcg tcatcaaaac ggtcgtcatc aggacgttga
     8881 caatcactac cacaagtacg gcccagagtc agtattctga atgacctaaa atcttcccaa
     8941 tagcccagat agccataatt ggaccacgcg ttaccacttg caagcccata gtaatcaaca
     9001 tttgaacttg agtaatgtca ttggtagtac gcgtcaagag gctaggaatt gaaaatttct
     9061 taatctctgt ctgcgagtaa tccaaaactc ggttaaaaat atcacttctc agcctactag
     9121 tataagaagc cgccactcgg gatgcaaaaa atccaactgc aactacggac aagaaggcaa
     9181 gaaagagcat tcccatcatc atgcttgccg gctgccacaa ctcatctaaa ttagtttctt
     9241 gactacctag caaatccgta attttcgaga tataggtcgg cacttccaac tctagataga
     9301 ccgaaaagca agtaaagaaa atggctagta aaatcatccc ccattctttt ctactaattc
     9361 ttttggttaa tttctttatt ctctcctcct attcccttga tattttgcct gtagttgacc
     9421 gagaactttc tcaaaaatca gtaattcatc ttcatcaatg tcttccatca actgcttgtc
     9481 tatgcgttca aaaaaagcct taacctgttg catctgagaa cgtgctttgt ccgtcagacg
     9541 aacaaactta gcccgcttat caacaggact cgcctccaat tccaccaaac cattttgcac
     9601 tatacgctta accagattac tagcaacaga cttggtaata ttgagttcct gctcgatatc
     9661 tttaatcaag accaagtctt ggtttttcta gcgattatcc aaaaaacgca caacctgacc
     9721 ttgcggccca cccataaatt caatgccgca acgtttggct tccttttgca ccatcaggtg
     9781 aatttgatga ccaaaacgct taaagactaa catcggttta tccataatct cccccttcta
     9841 aataaaaata gttctctgga gaataattaa atttctatga gaactatttt cttgattaaa
     9901 aaaatcccaa gtgattttct cacttaggat catgttctat aggttaaatt aaaacccatc
     9961 tacgttcgta taaatctttt ggacgtcttc gtcgtcttca agaacgctgt aaagtttttc
    10021 aaaggtttca aggtcttcgc ctgacaattc cacttctgac tgaggaatca tttccaattc
    10081 agtcacttgg aattcttcaa taccagactc acggagagca acgatagcct tgtgaaggtc
    10141 agttggcgct gtgtaaactg tgattgtacc ttcttgtgct tctacgtcat ccacatccac
    10201 atccgcttcg agcaattgct caaagactgc gtctgcatct tcacctccaa atacaataac
    10261 acctttgttg tcaaagaggt aagaaacaga acctgaagcg cccatgtttc cgccgttttt
    10321 accaaaggct gcacggacat tggctgctgt acggttgacg ttagaagtca aagtatccac
    10381 aattagcata gagccatttg gcccaaaacc ttcgtaacgt ccttctgtaa aggtttcgtc
    10441 tgtgtttcct ttggctttat caatcgcttt atcgataatg tgttttggca cttgggcttg
    10501 tttagcacgg tcgataacga atttcaaagc tgagtttgat tctggatctg gatcaccttt
    10561 tttagctgct acatagattt ctacaccaaa ttttgcatat accttagagt tagctccatc
    10621 tttagccgtt ttcttggcta cgatattggc ccatttacgt cccattagga atctcctttt
    10681 ttcacatttt aatctttatt attataacac aagttttttt gattttcact agaggaaatg
    10741 gattttatta gcaaatcaag ctaggatagc actttacctg ctaagatggt cttacctttc
    10801 tatctttatc aacagacact catccacatt caaaaaacaa actagaccat tatctgcaaa
    10861 tagaaagttt cagccaagtt tgacaaagtc agctcaaatt actgtttgaa gtttgtagat
    10921 ataagcgaca aaaacaatca tactgcacct tttgttgaca gtctactcca gacatatcat
    10981 agttcaagta aatactttga aattcaacag ttcttatagg cgctattgta ttctaagaaa
    11041 tcaatagaag agtttctaag caaacctcta atactcaata aaaatcaaag agcaaaccag
    11101 aaagctagcc gcaggttgct caaaacactg ttttgaggtt gcggatgggg ctgacatggt
    11161 ttgaagagat tttcgaagag tataatttac gtgttcccaa gatggagaag ttagactagt
    11221 acactggcac ttctaaacca ttgctagcaa ttgatttgtt catatttaat ttcatttttt
    11281 ccataaatgg gtattagata taaacagcaa aatatttccg atacgtgtcg ttcttgaatt
    11341 tccaatcatc taaaacaagt aaaggataat caatcccctg tatatcaagg aattggctac
    11401 cctttttact tttttacaca ttctgtttga tagattcatt ttaacatcac gagcatactc
    11461 caatggaaat cgctaggcaa gagataaact ttcagatatc cgcagagaga tcatcgcctc
    11521 tttttgtcgc aagcattctc ctctcctagt cattttctac cttatcttct acctgaggat
    11581 agagagttgt tccccaaata gaaatcgtcc gcttacgcac tagtggcaaa tcggtttttt
    11641 cataaaccgt acgccaccat tcccaggcaa gcccggtaca ctctctaatt ttgacagaga
    11701 gattacgaac attccctttt aaaggaatac tagtggtaaa gtgagccgtt aaatcctgcc
    11761 catttctgtc ccaagcctta ggagtcaaga cttccttacc ttgatgatca taggataatt
    11821 cattccaagt aatataatat tgggcaacat aggcaccact atgatccagc agtaaatctc
    11881 cgtttctgta agctgtaacc ttagtctcaa catagtctgt actattttga aaggtcgcaa
    11941 ctacattgtc acgtaaaaaa gaagttgtat aggaaatcgg caagcctgga tgatctgctg
    12001 taaagcgact gccttcttga atcaagtcct ctaccatatc caccttgcct gttacaactc
    12061 gggcacccga acttgggtcg ccccctaaaa taaccgcctt cacttctgta ttgtccaaaa
    12121 tctgtttcca ctctgtctga ggagctacct tgactccttt tatcaaagct tcaaaagcag
    12181 cctctacttc atcactctta ctcgtggttt ccaacttgag atagacttgg cgcccataag
    12241 caacactcga aatatagacc aaaggacgct ctgcagaaat tcctctctgt tttaaatcct
    12301 ctaccgttac agtatcttga aacacatctc ctggattttt aacagcatct acgctgactg
    12361 tataataaat ctgcttaaaa ttaacaatct gaatctgctt ttcgcccgaa tggacagagt
    12421 taaaatcaat atcaagagaa ttccctgtct tttcaaagtc agaaccaaac ttgaccttga
    12481 gttgttccat gctgtgagcc gtgatttttt catactgcat tctagctggg acattattga
    12541 cctgaccata atcttgatgc cacttagcca acaaatcgtt taccgctccg cgaacacttg
    12601 aattgctggg gtcttccact tggagaaagc tatcgctact tgccaaacca ggcaaatcaa
    12661 tactataagt catcggagca cgatcgaccg caagaagagt gggattattc tctaacaagg
    12721 tctcatccac tacgagaagt gctccaggat agaggcgact gtcgttggta gctgttacag
    12781 aaatatcact tgtatttgtc gacaagctcc gcttctttct ttcgataaca acaaactcat
    12841 cgggtagctg attaccctct ttgatgaaac gattttcaat actttctccc tgatgggtca
    12901 agagtttctt tttatcgtaa ttcatagcta gtataaagtc atttactgct ttatttgcca
    12961 tcttctacct cctaataagt tcctggattg agttgcataa actcagactt gttcagcgaa
    13021 atcagccgtg gttggactaa gtaatccaaa atttcctcgt acaattcttc tgagacattg
    13081 cgtcgccgtc tggctagata agaagtcgga atgcccgtat tatccaacat aaatacctta
    13141 tctaagtcaa tcaaggttgg tcttgtaaaa ggattacgag ctagatccgg ctcttctatc
    13201 ataaagttct tgaccaaacg tctggtcaag agagctggtt tgaaggtctg atttttaacc
    13261 aactctttgt ttttagtcat gctgttgtca atacagatat acatatgatt cttcacagcc
    13321 aaatcgctac taatagtcgg aaaaggcaaa taaagagcta caacatctcc tctcttaatc
    13381 aagcaagagc accccctttt ctcctaatgt aacatagaca ggattgacca agtcttctga
    13441 ttgactcaga atttccaaag tttgagtttg gcgcgctgtc aatttagtag catcttgtct
    13501 cttcaataca aaatgcttgt cgccaataac cttgacaata taatccttct ccaaagctga
    13561 ctggtaaatc cacatcagat gttgtctgtc ctgagaactc aagagagaag gattttcaag
    13621 cctcccgata gtctgataaa aatcaaaaac aggagctaac tcctgccaat ctgattggct
    13681 agttgtcaag gctagaaaaa gggctttgcg agctgatact tcttggttag ccttgagagt
    13741 tactttcccc tccaagtttt ttagaaatcg ggaaactcca gaaagcaaat ttttctctaa
    13801 ctgcgagaaa taaaaacctt tcgttcccag acataagtct ttcatgtcgc tttctctagc
    13861 aaataagagc tcaaacattt gatagtaaaa gaaaaatatc tggcactggg tcgcgctcat
    13921 cttttcctta tcggcttctt tttttaacca gagcaagggc gacaggtaac tggattgaga
    13981 catttcctct acctcctact cttttttaac tggagcatct gcactagctg ccacttcttt
    14041 tgactggata ctttcccact ggttaatctc ctctgagata agaccttcgc atgtcttgac
    14101 aaatagggca aaagccttgg tctttcctgc atatttctcc gtttggcatt gatagaggaa
    14161 tttttctttc tccaggagtt gcgcagtttt ttggtaagaa atccaatttt cctttgcatt
    14221 atacaaattg ataatcccct cacacagcaa gccgagactg gataaggcaa ccgaaatcaa
    14281 acggtagcga tcacctggca taggaatagc acaaaagaca gctatgagga aacctgccac
    14341 gatttctgtt atttttaata ccttatagcg cctacgatgt tgaacgcttt tctttaaaaa
    14401 atgagctatc tgtacgtcta atcgctctgt caggtacatt tcttctggcg tcatattcgt
    14461 aactcctttc atttactttg ataaccatag tataacatat ttgaatatca aagtatagta
    14521 aaaactggac tataacttat tagacttcct gcgaaacaaa atatggtata gtagttctat
    14581 gaattatgaa gcaagtaaac aactaactga tgcacgattt aagcgtcttg ttagtgttca
    14641 gcgtaccact tttaaagaga tgttagctgt attaaaaaca gcttatcaaa aaagtcggac
    14701 aagctggtaa aatcttggct gacagtggtt atcaagggct catgaagata tatcctcaag
    14761 cacaaattcc acgtaaatcc agcaaactca agccgctaac agttgaagat aaagcctgta
    14821 accatgcgct atctaaggag agaagcaagg ttgagaacat ctttgtcaaa gtaaaaacgt
    14881 ttaaaatgtt ttcaacaacc tatcgaaatc atcgtaaacg cttcggatta cgaatgaatt
    14941 tgattgctgg tattatcaat cataaactag gattctagtt ttgcaggaag tctattatat
    15001 atatgcacag acatatgaaa tctttttgat acagccttct ttttacatag agagacagca
    15061 gttatgatat atttatccat tcacaaaatc ttctgtacca atactacaat aattggtaca
    15121 ttttgattac acaatcgttt caaaaaatat gatggaagac tgagtatttt atagtaattc
    15181 ccttcctatc aactagatca accagttgag tgttgaatgt tgaaacaccc tagcctcagc
    15241 aaaggactat gatcagcatt tcctagccaa taggacgctc caaatcacct attctaagtc
    15301 catcactagc ttggtcagta agatacagac tgcaaggcaa gactgacgtg gttgatgaga
    15361 ttttggaaga gtattacaat catagattca ccagtagact tgaccgcaga tttaactata
    15421 gtagattgaa actagaatag tacacttctg cttctaaaac attgttagaa atcgatttga
    15481 ctgtcctgat caatttgtcc tgttctcgtt tcattttact atactaaaaa accacctgaa
    15541 acaaatcaag tgactagagg ataaaaacaa agactgggca aaaagttttg aaaagcaaaa
    15601 aacgcataat atcaggtctt gaaaaacctt gctactatac gtttgattgt gggaagattg
    15661 acttcatttt ctcctgaaat tgaagttttt tctagtttcc aggtatagac gaattcaata
    15721 tagccatctc gctacaatta ttttaaccat cgaaaaaatt tttcagaatt tcaaaaattt
    15781 cattttgatc caatgaaatg tcattatttt gaagaatagt tgactttaca ggctctaatt
    15841 ctatcacaaa gcggtgcatg tctgctttta ccgcactact tgatgttata gccgataact
    15901 tttcatctcc tagcaaggaa gctgtcaaac gggtaaggtc attcaaatgc tttttaatgg
    15961 acttacttaa accttgagca cctgtggcag agcgctccct catatccagc caagctttag
    16021 ccttaaaaat aattaatact caatgaaaat caaagagcaa actaggaagc tagttgcagg
    16081 ctgctcaaaa cactgttttg aggttgtaga tggaagctga cgtggtttga agagattttc
    16141 gaagagtata gaccacaatt actcaatacc gaatacccct gaatggtttc ttttaaatgc
    16201 accaatatat tataataatc ttcatccaat aataaggctg ataaactagc atcttggtca
    16261 aaatataagg gaatttctcg accgtccttc tttaatggat attctggtaa gatactaaat
    16321 agttcaatca tagaaggaaa ctcagaatta gttgttgtaa atcgaaaaag ctgcgctttc
    16381 tcatctttct gacttccttg atactctccc aattctaaaa aatgattcaa ggtagtataa
    16441 aattccttat tttttacttc atcaatgatg accatatcat aatcttttgt tgtgcgactt
    16501 ttaaatcctt gcgaatccaa tacgatagag gtagcagttc ccccaatcag aacataatag
    16561 ttctgaaaat ccgcaaacat ttcttgaaaa ataactttcg tattagctgg catcatcttc
    16621 tcccagatac tgtaatatca tattttctag tgcttcactc tcttcctcta tacgtgggtc
    16681 atcatcatct tttaaggtca aataaagaga aatcggatct acaaattgtt tatcatgatt
    16741 atttttaaaa tcattccaaa actcagatac aaaaggacga tatttccata tctctagcat
    16801 ctttcctttt aaaatatgct gagaaagtgg caaggataac tgattgaatt ttctctgcca
    16861 tatgacatag ctagtatttt catccgtttc agctaaaaaa gttgaatgcg acaaagcata
    16921 agcaccacca tatagaaggt tagaaacaga ttttatctgc tttatatcgc catctggcaa
    16981 taaaatccgt tttttgatgg gattaaataa acatgacacg gattttaaga ataattcttt
    17041 ctttgacacc gtatatgtgt aaagcttatt ttgcttgttt aaccaatata aagctttaaa
    17101 agtcctcaaa cacctataaa ttgttgagtt tggaagtcca gtgacttgtg aaagcaaatc
    17161 aacatctact actttttgac cttttgtcaa taaaaaggca atccacgtta attgttcgct
    17221 aggtgttaat tccttaggga cttcagtatc attcgcattg agtactagtc ccaatggagg
    17281 gaagaagagg tttcccttaa agtctacaaa cggaactcta gcttgaagta attgcttttt
    17341 ttcactgtct gataacttcg aaaacaccaa aacaacatcc atattggctt tttcacccat
    17401 agtgcgagcc tgagtaacaa atgaactcaa actccccctt ctcttttctt taatcaataa
    17461 aaatgattcc ttatgaaaag tcatttgagt atactcaaac ctttttacaa aactgattgg
    17521 taaagtcaaa gtcagttcct caatactgac atcaacataa aaggattgaa aaattgacat
    17581 tatctttttg acattcatgt tttttcctta ttctatcatt tttattatat tttatcattc
    17641 ggtataataa aatataagtt ttttgataaa ataaccaaaa actactccct atcccctctc
    17701 acattaccct acatatcgtt tgacatgcga ctgatagttc aggaaaactt caaggagaac
    17761 ttttctctca tccactatgc aggacttact atttcacttc tactcctata ggctcaattt
    17821 gacacttttc tttttcgaat tgctcatatg cctcctgaat agtgagttcg atttatccaa
    17881 atttattttt gtctattttg atgaatactt ccacgaagat agtctgaaaa tgaatttgca
    17941 ccaattttcc ttctcttttt aagcatatta ttccagatat gattgccctc ttgttcagta
    18001 ataaattacg ctttaaacgc ttcaatcagt atatctcctg ttgtcatatg ttctaaagaa
    18061 aattcttcta catatgattt aacatctctt aggttattac ttcctaatat cccattatgc
    18121 tttttcgcta aggaaataga agccgcttct cccttaccaa taatcttgtt actatcatga
    18181 tttcttgtta aatctctata taatgcgtat tcttcagttc caatgtctat gctcacaatc
    18241 tcagctgaac ccttagctac caactgatct atcctagatt ttaaatgggg aattgtaggt
    18301 atattgattt catcatacac ctcttgtgga ataacaattt tacccgaata gagcttttct
    18361 aaaagatgtt cagtaccaac ccataaaaat actgaaatac aatctgcatc aataaataca
    18421 cgactagtca aacgacaact cccccctctt catctagccc atatacaata tcatatctga
    18481 aagcatctag taacagttcc tcatacttcc cttgcgaaat tctgttattt tctaaaagtt
    18541 gttcagttga attaacatat tatcctaata tcatttactt tttactttct gacaaaggac
    18601 gatataaact tgtatcatag cctaatcttg aagctgtctc tataacacta atatccatat
    18661 ttttaatttc ttctgcatca aggtatccat cattcctcaa tctatataac ataactttat
    18721 gactgatacc ataaaactga cccaatttta taatatcttc tacttcaaga tgagttctat
    18781 tggcattttc tctaatttcc tcaaccatcc tatacagtga agatgggaaa attaaaaaat
    18841 aagaagcaaa ctgatccgct tttctttcag tttcatctcc ttcaccaatc aagataagac
    18901 tgactgaact cttcttcacc tcatcataat aaagatgata cagttcatgt gctaaagaaa
    18961 atctttacct tcctaatgac atgtctgaat tgactgcaat gagactgaac tgagttcctt
    19021 tataacagac tccgctaata ttctttccga gtccataaaa taccagcgtc aaattttcta
    19081 tcttttgtac caatttaaaa atatctatcg gcgattcacc atcagctccc aacttttttc
    19141 taagatttga agctttatta cttaaatcca ttcgtgatat tcctttcacc tttttccatt
    19201 ttggcaatca tgctttgatt caaagacaaa tactcagcaa tcttatcttg agtaagattt
    19261 gaagatattc taagttcttt tattcttttt ccaacatcac atacatttat cacatacatt
    19321 tatcatattc atacacctct cataaaaaga atagcacact tttgtcataa ttttttaaat
    19381 aaaaaaatta tgacaaaaca aggaagcaat ttattgatgc tgcttaaaaa tctaaaattg
    19441 atgagttcct atcaaaaatc gtatcttcaa cctcaaaaca gtacttaaag ctatccgact
    19501 cggtttacat tgtcaaattt agattttatt tgagcataac tttctagttt gctttctgat
    19561 ttttgtttaa tatagtagca aacattgaag gaaatatctc cacaaaaaaa cgcatactat
    19621 taagcttttt caagacctaa taatatgcgc tgttctgatt tgaaagacat tccattatta
    19681 ttttactgta atcaagccat ctggctctac tgtgaattct ggcttgtctg ccagtgttcc
    19741 gtctggtttg aggtagtacc agcctgttcc gtccgctgac tggataaagg catttgatac
    19801 catggcgcct tctttagcgt ctaagtagta ccaagtgtcc ttgtacttga cccagcctgt
    19861 cttcatggca ccttcttcgt tgaaatagta ccacttatca gcgattttct tccagcctgt
    19921 agccatttcg cctgagttgt cgaaccagta ccagttgccg tctgtgtgct tcctccagcg
    19981 gtctgcaagc atatagcctg aactgtcaaa gtagtaccaa gtgccattga ttttctcaaa
    20041 cttgtctttt ggataagagc cgtctgaatg tacgtaccag tagccagtgt cattcttctg
    20101 ccagcctgtt tcaatcgtca agccgttctc aatatcatac ttaaactgct cacggctaat
    20161 gccccatttt gccaagtaag ggtatggatc cacatggtct gagtggttgt ttggttggtt
    20221 attcgtgcaa tactcgtgcg ttttaattcc agctaaactc cctgtatcaa gcgttttcgg
    20281 caaacctgct tcatctgcta gattgcgtaa gagttcgata taaaggcggt agtccgtcat
    20341 gaactcttct ttagttgaat ggctttcaat cagttcaacc gctgcatagg tttcagcatt
    20401 ccaaccgccc ccaacgtccc aggcaccatt atcaacaggt cctacctgca tgatgcaacc
    20461 gttcccaaca atgtgcgaga aaaaacctaa ttctgggtct ttccgccagt gataatccgc
    20521 ttcattctgt acggttgaat gcggattccc agttgagtgt gcgtgtactt gcctatatgg
    20581 ttgcacgccg acttgaggca aatctgttct taatttactc acattaattt ccatattcta
    20641 ctccttatca attaaaacaa ctcatttttt acaatccaga accagaaact cctttatttc
    20701 taccttacaa agaagacaat cttagtcacg attaggcttg tagatagaac ctcaaaacgc
    20761 actattttga cactgtaaat aggactgaca aggtctgcat tctatctaca ataacacccc
    20821 agactaaaaa gcttttcaaa agtatatttt tacagtctct atatgtcctt ttcataaata
    20881 ctatacttta ttatatcata taaaagaagt caaaagtctg ttaaactatt ttcaacacca
    20941 aactaaagaa gagaacacaa gttttttcga tgttcactag aggaaatgga ttttattcag
    21001 taaatccaac taggattgca ctttggttgc caaaattgcc tttccttctt ttatcaaggg
    21061 atgacggaat agtgagaagt acagttgaac tgtcatggca acccagataa gaggttcaca
    21121 aaggataaca cccttatatc ctgcccaagg aataatcaaa accacaaaaa cgatttttcc
    21181 gattagttca ataaagctag aaactagagg aaggatcttc tgccccaagc cctgcaagca
    21241 attgcgataa atcaacaaga ggctcaaaat gggataaaag gctgaactga tttgcagata
    21301 gagacttcca ttttctatca agtaaccatc tgtcgaacta gccaagaagg aaaccaaggc
    21361 tggactggca aaaaagagga aaatacaaac aaaaactgcc caggatatac ttaaacgact
    21421 gccgattcga agaccttgaa caatgcggtc aggtcgctta gctcctagat tctgagaagc
    21481 aaaggtcgtc attgatgcag aaatagcggt cataggaaga agggcaaagg tcataatgcg
    21541 tcgagctgcc gtctgggcac taataatcac tgcaccaaat gtattaacag aaaactgtaa
    21601 aatcacactg ccgatagata caattgaact catcaagccc atagccaaac cttgctccaa
    21661 gagatccgcg tacaagcttt tgtcccattt gaaatgttta aactgtggca agagttctgg
    21721 cacactttta cgaatataat aaaagcagag aaccgctgat aaaccttgcg aaataatggt
    21781 agcaagtcct gcggattgaa ctcccagatg caattgcgta ataaaataga gatccagaac
    21841 cacattaacc aaggcagaga aaatcagaaa tcccagggct gctagactgt caccaataga
    21901 ccgcaacaag cctgcaaaaa gattataagc aaagctgaca cctacacagg tcacaatcat
    21961 agaaatatat tgataagatt gaggaagaat ttctgcagga gtatctaagt attgcaagag
    22021 aggatacaag ccaagaaagc ccagcaacat aactagaatg ctcaaaagag cacctaaaat
    22081 ccaggtggct gctactgctt ccttgatttt agtgaaattc cgagccccat aataacgagc
    22141 aatgacaatc cccatgccat tgccaacacc aagtgtaaag cctacaatca ggtcaaaaat
    22201 cgctgtcgtc gctcctactg cagccaagga ttcttgacca agaaatcgtc caacaatcaa
    22261 gacatcagca gtgttataga gctgttgaaa aatatttgat agcaagattg gaaaggtgaa
    22321 gcttaagagc gagggaagaa tcggaccatg tatcaggtcc actgttcgtt ttttattcat
    22381 aaagctatta tatcagcttt ccagaggagc gacaagaaac agcaaactta tatatagcgg
    22441 aatgaaataa ggacagtcaa atcgattttt aacaatgttt tagaagtaga tgtgtactat
    22501 tctagtttcg atctattata gttggttgag tttggaatag tacgctgtag ctgctaaaac
    22561 atttctagaa attaatttga ctttcctaat aaagttgttc atatcttatt tcaagctact
    22621 atatataatc taaaaacttg aatcaaaaat cgaaaaagta gcggatttct ccactgcttt
    22681 aacagcttat tcttcaattt cgatttcaag ttcatcgcct aagtcaagcg gaacttcttc
    22741 attcactgct tcttctttct ttggctcatc ttttttgttt tcagtatctt gttctgaaac
    22801 ttcttctcca tcaatcaagc caaatttaga acggacttgc ttatcaattt catcaaagat
    22861 ttctgggtgc tctgccaagt atttcttagc attctcagaa ccttgcccaa ttttttcatc
    22921 tttgtaagaa taccaagccc ctgctttttt gataatatcc aaatcgcttg caatcttcaa
    22981 aagctcacca gtcttagaaa ttccttctcc gtacataatt tcaactacgg cttccttaaa
    23041 cggtggagct accttatttt ttacaacctt aatcttagtt tctttaccga cattggtttc
    23101 tttttgatca ccagttccct taatttgtgt attaccacga acatccaagc ggactgaagc
    23161 atagaatttc aaagcacgtc cgcccggtgt tgtttctgga tttccaaaca tcactccaac
    23221 tttttcacgc aattggttga taaaaatggc aattgttttg gttttattga tagaggcgcc
    23281 aagtttacgc atggcctggc tcatcatacg agcctgcaaa ccaacatggc tatctccgat
    23341 atctccatca atttccgcac gaggaacaag ggcagcaact gagtcgacta cgacaagatc
    23401 aactgcacct gagtcaatca attttcccgc aatctcaaga ccttgctctc ctgagtctgg
    23461 ttgagacaag agcaattcgt caatattgac accaagggcc gcagcataag ctggatcaag
    23521 ggcatgttcc gcatcgataa aggcagcaat cccaccttct ttttgcgctt gtgcaactgc
    23581 atgaagggca accgttgtct taccagatga ctctgggcca tagatttcga tgatacgtcc
    23641 cttaggataa ccacctgagc caagggcaat gtcaagagct aaagaacctg agctcatcac
    23701 ttgcaccttt tgctccgcac gttcacccaa acgcatgatt gatcctttac caaagtcttt
    23761 ctcaatcaat ttaagagcat cattcaaggc cttttcacgt tctgccccaa atttttttga
    23821 aatttcttct aatttttttg gttttttcgc cattctattc tcctacattc taatgatcct
    23881 cagacctatc tactattata tcaaaagtta gtcacttaat aaagccttgc gaactaggtt
    23941 aaaggcatgc ataaccgcaa tatgacgtac atctgctcgg cttctgcctc caatattaac
    24001 cttgataacc tcagttcctt gctcttgcgc caagcctatg aagactgtcc caactgggtg
    24061 tccttctagg ctatctggtc ctgccactcc ggtcaaacta attccaaaat cagactgggt
    24121 cttgcttcgt gcctgctcag ccatcttctg agctgtaaat tcagacacca caccatgttc
    24181 ttccaaattc ttggcaggaa tatccaacat ccttgatttt tcctccaagc tataggtcac
    24241 aaaaccaccc ttaaatatac ttgaagctcc agaaaaattc gccacggtag cttggaaaag
    24301 acctgccgtt aaactctctg cagccgcgat ggttttccct tgccttttca gttcttctac
    24361 cacaatgctg gctaaactag tttcttcccc ataaccatag caaaagtctc gtaaagaaat
    24421 tccttcgaaa gtctggcagt ccaagatttg attttccaag atatccagcg cttgattcgc
    24481 ctcttcttga ctgctagcct ttgttgacag acgtagagtg acttctcctg tcttggcata
    24541 aggggccaag gtaggatcga tctgattatc aattaaatca gccaaaatcg taaccaactg
    24601 gctctcgcca atcccaaaga aacgaagaac tcgggaatac agcttgctcc ctgtcatcaa
    24661 cttgggtaga agttggttta agaccatggg tttcaattca cttggcggac ctggaaggac
    24721 gacataggtc actccgtcta cttctaattt tcctccaaca gccagtcctg tttcgtttgg
    24781 cagtggaatc gctccttcta caatttgagc ttgtctttcg ttattcggtg ttcgggcata
    24841 gtctggtcgc agggcaaaaa agatatccaa cttctcctga gcctgaggat caaagactaa
    24901 tgctttccct aaaaatttag ctagggtttg tttggttagg tcgtcctcag ttggccccaa
    24961 accgcctgtc aaaatcacca gactgctacg ttgactggca atctcaagca aagacaagag
    25021 acgaacttca ttgtctccta cagccgtctg aaaatataca tctaccccaa tctcagctag
    25081 tttttccgac aaaaactggg cattggtgtt gacaatctgt cctgtcaaaa tctctgttcc
    25141 aacagcaatg atttctgctt tcatgtttcc tcctacctat ctattcgtat ttttttgaaa
    25201 aaatcgcagg aattttccta cgattgattt ttttatttgt atcaaaagtt aattatcttc
    25261 atcaccaaca ggtgctctgc caaataaatc ttcaaataaa accgcattgg tttcaagctg
    25321 agtaacttct tcttgtccca aagaacgtcg gagtatattt tgcatttcca acatatgtgc
    25381 tctcgaaaca atctggtaag aaacaccttg aagtatctct ccttcaccct gcaactgctg
    25441 agtttcaatg gttttaaatg aatctttata gcctagcaag ttagggatac tttttgcaga
    25501 caaatcaata ttggtctgca tattgtcact caaagctttt agaatctctt gataatgacc
    25561 aacgctattt aaactgagag ctttttccat gactttttga ataacttcac gttgacgttt
    25621 ttgacgacca taatccccct caggatcttg gtaacgcatt cgtgcataga ctagggcttc
    25681 ttctccccca atatgttgct ccccaacacc gatagaaata gtattaaatt cttcttggtc
    25741 actgatagaa attgggaaac ctaggatatt attgactgta atacctccta ctgcatccac
    25801 tagtttttgc aaccctctca tattgaccat cacatagcga tcaatatgga tattcatcat
    25861 tttttgaatg gtttctatag caagctctgc tccaccatct gcatatgctg agttcagttt
    25921 cgcttcatga gcctgaccat tccctgattc aatgcgcgtc agaatatccc gctctaaact
    25981 catcattgtt gtttttttcg ttttaggatt cactgtcatc aagatcatgc tatcacttct
    26041 accgacccaa gtttcagttc gttcaacatt tccggtgtcc actcccatta acagaatggt
    26101 tagaggttca gtcgcttcaa taaccttggt ttcttcaccg atttttttat aggttttagc
    26161 taaggtttct gtcccttgtt gataaatagt ataagcaaaa acacctactc ctactacagt
    26221 tacagaaagt aaagctagca ccattccaat aattttttta accatatttc tactaaccta
    26281 tcagtttacc catcaagtaa acatcgataa atttcccttc ttctatatat gccccacgct
    26341 cttggctacc ttcaatgaca aagccatgct tttgataaag atggactgct gcttgattac
    26401 gagtttggac agtcagttgg agacgacgca gaatgccact tgcttgtgcc cactctatcg
    26461 cttcttctag caacaaactt cccaagccat tattccaata tctttttcca atcacaatga
    26521 agagttctcc aatatgacgg actctcttac gctggtcagc tgtaatattt acaataccag
    26581 caattttgcc atttaagaat gcaagtaagg ttatctgatt gtccgaacta gcttgcttgt
    26641 tgaggaatat ttccatctcc tcactagtca agagaatacc atctccgtct aggctggtaa
    26701 agtctgtctc caaactcaca cgatttaaaa aggccactaa ttcagctgca tctttgggct
    26761 ctgcttccct aatgagcaat tcatactcca tattgaagct cctctaacaa tttctcagca
    26821 cgcaaaccct ttgcctgaaa atttaaacgg cgtccatctg cttcttttag aatttccaat
    26881 tctaaataag catctggcaa ggcatctcct aagagattgc cccactcaat aacagtcacg
    26941 ccgccaccaa agataaactc atccaagtcg atagaatcag catctccttc aatacgataa
    27001 acatctaggt gataaagtgg aagtcgacct tcatactctc tcacgatagt ataggtggga
    27061 cttttaatca tttgagaaat ctgtaatcct tttgcaagtc ctttagtaaa ggtcgtttta
    27121 cctgcaccca gttctccagt taagattaaa acatcattct ttgctaatag atggcccaaa
    27181 cgctccccta aggcttgcaa ctcttcttca ttttttgtgt acatactctt attataccaa
    27241 aaacttttct tttgtgtcta ttttcctact aaacttatca tcataacatc cataaaaaac
    27301 aggctttctc taaaagaaaa tgagcgtaac aatgaccaat acaagatctc ggaaaatatg
    27361 accataaaag gaaacttcct tcttaaccga atttgggaca agataggctg caaaaaacaa
    27421 gcccagtcca atataaatca gaagtgagac aatggtcatt ggatttctta agaaaagaag
    27481 tgttgctaaa atagtcacca acactgtctt ttttctgtct agcatagcaa gaaaatcgcg
    27541 cacgtatttt ttcaagggta aaaaaatcag caaatctagc ccaaatagga aaaagaagga
    27601 tggcaataaa aagtcaacta attcttgctg cagcgtattt ttgatgaaca agttatctga
    27661 caaaacaaga acagctccta acaaattaat taagagtaac atactgtaaa aaagcttcac
    27721 agacttctta ctggctagga cactatggac ttcttgctta cgggtataaa gataatttac
    27781 tccagcacag attcctgaaa cgaaaaccat gcttccgatg aaaaaaactg tactttgttt
    27841 aaaggacaag atgcattcct tccataggaa acagctactc aaactgattt gaattaaagc
    27901 taacaaaaat aagattctca ttgatttcat cttctctctc ccttcctacc aatcattata
    27961 ctaggagaaa agagagaact gtttctaatc ttctcaaatg tctctttaag acgctaaaca
    28021 aacactagag actaatactc aatgaaaatc aaagatcaaa ctaggtagct agccacaggt
    28081 tgctcaaaac actgttttga gattgcagat agagctgacg tgatttgaag agattttcga
    28141 agaatataaa tttgaaatca tgaaaatccg tcaaacgggt ggttgttttg tctcgcacct
    28201 cacggagcga gacggactca gagtcacata attataaggc tgatagtatt aatctaacta
    28261 tcagccttac aggttattta acgtttcaga aaaactataa tgtcaagatt aactaaacag
    28321 tatctaattc cttcaaataa ttttctatct tcatcaacat taaaggattg ttataaatct
    28381 tacataactc tcttgcttct atataataat ttttgacttg ttctctgtct agaaatttgg
    28441 ctccagcatt tcctacaaga ataagtagag gagccaattg gtagcttgtc tgtctttgtt
    28501 tacagagttc aatcgtttca agagcttctt ggatggcttc attatatttt tcctttgata
    28561 ctaggtagtg agcgtagttg taacgaactc tgatgtagcc aaataaaaac tcttgatggt
    28621 ccaaattttt tgtctgatac aactctatta aatgagagta gtttgcctca tattcttgtt
    28681 cacgacccac taaggaatag aaattagata gagtattcaa cgcctttaaa taaatcagag
    28741 tatttgaaga gacttttaat aatatatttt ccaatgacga aattgcctca cacttactgt
    28801 catattgata gaagtcaatt atagatttaa tccattcaag gtaagttcgg tcttctaatg
    28861 ttagaaaagt gcttcgttct acctctattt tataaagata ttctaaatcg tcataatttc
    28921 tgtcatctaa taggcgagca gatagatgtt tgaaattaga gaggttagac ttaacttcga
    28981 tttgttcatt gaaaaagtaa tccaaaggga cttcaagtcg ttgagagagt ttgaataaca
    29041 agtctgcgga gggaataaaa tgacctcttt caattttact aatctggctt tgttcacaaa
    29101 ttccttccgc aagagtttgt tgggagagtc tcaactcttt tcttttcaat ctgaatttct
    29161 ctgcgagtgt attcattaaa gataataa
//
LOCUS       DAVLBE010000023        27737 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.023, whole genome shotgun sequence.
ACCESSION   DAVLBE010000023 DAVLBE010000000
VERSION     DAVLBE010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 27737)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27737)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27737
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.023"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(97..732)
                     /locus_tag="VXB91_001086"
     CDS             complement(97..732)
                     /locus_tag="VXB91_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-alkyl-2-acetylglycerophosphocholine esterase"
                     /protein_id="HEV0470554.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKTIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVARDYPLTEIKLLSILPVNEREEYQQAVYIRSNEKIQNWNQAYQEL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKSLKDYLY"
     gene            complement(734..1561)
                     /locus_tag="VXB91_001087"
     CDS             complement(734..1561)
                     /locus_tag="VXB91_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV0470555.1"
                     /translation="MMIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAQTWDDAIVNKALTHFKGRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINALFDGRVRAVSSGYGCIDILQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(1583..1918)
                     /locus_tag="VXB91_001088"
     CDS             complement(1583..1918)
                     /locus_tag="VXB91_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-gamma-glutamate biosynthesis protein"
                     /protein_id="HEV0470556.1"
                     /translation="MGNFISNQRIESMGDEENAKWTERGVLMDVTIKKKDGKTTIGTA
                     KAHPTWVNRTPKGTFSPEGYPLYHYQTYILEDFIEDGSHRDQLDEATKERIDTAYKEM
                     NEHVGLKWY"
     gene            complement(1919..2635)
                     /locus_tag="VXB91_001089"
     CDS             complement(1919..2635)
                     /locus_tag="VXB91_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HEV0470557.1"
                     /translation="MAHGDLLYHDGLFFSAKKEDGTYDFHENFEYVTPWLKQADLAIG
                     DFEGTINKDHYLAGYLLFNAPVEVMDAIKEAGYHVLDLAHNHILDSQIEGVILMADII
                     EKAGITPIGVYTHEPRAQAPLVIKEVNAIKVALLAYSYGFNGIEQYISQEDYNRYLSD
                     LNEDKIKAEVERAEKEADITIIMPQMGVEYRLEPTEEQKALYHKMIDWGADIIFGGHP
                     HVVEPSETVEKDGDKKLIVY"
     gene            3148..3759
                     /locus_tag="VXB91_001090"
     CDS             3148..3759
                     /locus_tag="VXB91_001090"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEV0470558.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRTVAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEAIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            3804..4532
                     /gene="rlmB"
                     /locus_tag="VXB91_001091"
     CDS             3804..4532
                     /gene="rlmB"
                     /locus_tag="VXB91_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HEV0470559.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKSLSEITEGAVHQGFVLRVSEFAYSELDYILAKTRQEENPLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRTVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKDEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFRNRL"
     gene            complement(4571..5482)
                     /gene="trxB"
                     /locus_tag="VXB91_001092"
     CDS             complement(4571..5482)
                     /gene="trxB"
                     /locus_tag="VXB91_001092"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HEV0470560.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVREIKGENRVESVVFENVKT
                     GQVTEQAFGGVFIYVGLDPLSDFVKELNIQDQAGWIVTDNHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(5548..5772)
                     /locus_tag="VXB91_001093"
     CDS             complement(5548..5772)
                     /locus_tag="VXB91_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HEV0470561.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTARARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(5850..6593)
                     /locus_tag="VXB91_001094"
     CDS             complement(5850..6593)
                     /locus_tag="VXB91_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV0470562.1"
                     /translation="MIKISNLSKSFSGQTVLDHLNLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMSFVAQVADKILFLDKGKII
                     ESGTPDEIIHTPKEERTKEFFASYKRTYI"
     gene            complement(6593..7393)
                     /locus_tag="VXB91_001095"
     CDS             complement(6593..7393)
                     /locus_tag="VXB91_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV0470563.1"
                     /translation="MNVTTILASDWYQNLMQLIPDGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(7551..7907)
                     /locus_tag="VXB91_001096"
     CDS             complement(7551..7907)
                     /locus_tag="VXB91_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEV0470564.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLGVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNQEAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(7920..8432)
                     /locus_tag="VXB91_001097"
     CDS             complement(7920..8432)
                     /locus_tag="VXB91_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001170346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HEV0470565.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGKPQDLSNLLLAPIGTNFEKRVWDYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDINK"
     gene            complement(8432..8926)
                     /locus_tag="VXB91_001098"
     CDS             complement(8432..8926)
                     /locus_tag="VXB91_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0470566.1"
                     /translation="MEIRLAFPNEVDAIMQVMEDAKKCLADAGSDQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            9061..9507
                     /locus_tag="VXB91_001099"
     CDS             9061..9507
                     /locus_tag="VXB91_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HEV0470567.1"
                     /translation="MKTTFSYPKWAEIPNIDLYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMVNNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTVKLYHQTLDLIDHTQEEVIQ"
     gene            9504..10151
                     /locus_tag="VXB91_001100"
     CDS             9504..10151
                     /locus_tag="VXB91_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HEV0470568.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKKVNEKFSLALYLIMGWLVLAIIPAII
                     SQTTPVFWSLMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILAASALQYIAIVYYM"
     gene            complement(10172..10753)
                     /gene="pdxT"
                     /locus_tag="VXB91_001101"
     CDS             complement(10172..10753)
                     /gene="pdxT"
                     /locus_tag="VXB91_001101"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HEV0470569.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESHLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVA
                     AQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS"
     gene            complement(10754..11629)
                     /gene="pdxS"
                     /locus_tag="VXB91_001102"
     CDS             complement(10754..11629)
                     /gene="pdxS"
                     /locus_tag="VXB91_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HEV0470570.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            complement(11781..13160)
                     /locus_tag="VXB91_001103"
     CDS             complement(11781..13160)
                     /locus_tag="VXB91_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEV0470571.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKEKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALAGGKIELFRNGAF
                     LVDKKQETSIPDVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
     gene            13454..14377
                     /locus_tag="VXB91_001104"
     CDS             13454..14377
                     /locus_tag="VXB91_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEV0470572.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGIAPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     ILWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            14437..15042
                     /locus_tag="VXB91_001105"
     CDS             14437..15042
                     /locus_tag="VXB91_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEV0470573.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFTDKAEIELVEIKAIPV
                     FNKPADKQVPAEILEIAAKIEEADGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLSHSLQAFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEDFDWENL"
     gene            15061..16305
                     /locus_tag="VXB91_001106"
     CDS             15061..16305
                     /locus_tag="VXB91_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEV0470574.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRYFKLKFELEVLEIDEVPMF
                     NQDEKWDESFQLRYLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AFTGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAAGGHGDADATSS
                     ASDSGDAGGHGGDADATAGASY"
     gene            complement(16528..16785)
                     /locus_tag="VXB91_001107"
     CDS             complement(16528..16785)
                     /locus_tag="VXB91_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002901318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HEV0470575.1"
                     /translation="MDPKKIARINELAKKKKTEGLTPEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
     gene            complement(16827..18863)
                     /locus_tag="VXB91_001108"
     CDS             complement(16827..18863)
                     /locus_tag="VXB91_001108"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HEV0470576.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKGKRLSFEAI
                     QTFSTPRRLAVRVTGLADKQSDLTEDFKGPAKKIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEIGQAVEAIVPGIVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGSRVSRGHRFLGQETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKEIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKASLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEDFKPSVESLSRAFNLAEKAEGVATVDSALFENDQEKALAEAVETLILSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            complement(19123..20040)
                     /gene="glyQ"
                     /locus_tag="VXB91_001109"
     CDS             complement(19123..20040)
                     /gene="glyQ"
                     /locus_tag="VXB91_001109"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HEV0470577.1"
                     /translation="MSKKLTFQEIILTLQQFWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATSPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEMLLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRVKLLAEDAE"
     gene            complement(20059..20820)
                     /locus_tag="VXB91_001110"
     CDS             complement(20059..20820)
                     /locus_tag="VXB91_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEV0470578.1"
                     /translation="MDNLYLVKDDSQLATFRDFVVRNTEKLKDYQSFLKNELAVCDLP
                     QAVIWSDFNAATQIIRESAVPAYTNNRRMVMAPDLAVWKELYLYQLMDYECSEQTQAI
                     ESHYHSLSENFLLQIVGHELAHWSEHFLDDFDGYDSYIWFEEGMVEYISRKYFLTEEE
                     FQAEKICNQSLVELFQKKYGWHSLNDFGSSTYDKNYASIFYEYWRSFLTVDKLVENLG
                     SVQAVLDSYHLWANTEKTFPLLDWFVQQKLIEKEI"
     gene            complement(21093..21935)
                     /locus_tag="VXB91_001111"
     CDS             complement(21093..21935)
                     /locus_tag="VXB91_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEV0470579.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYRAVLESLKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQEEVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     VAQIALAWSLAEGFLPLPKSVTTSRIQANLDCFGIELSHEERETLKTTAVQSGAPRVD
                     DVDF"
     gene            complement(22050..23441)
                     /locus_tag="VXB91_001112"
     CDS             complement(22050..23441)
                     /locus_tag="VXB91_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEV0470580.1"
                     /translation="MNKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKVEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTSFIEDKKIEQDQSEQIVKNFSDQDLSAWNFDYKDS
                     QIILYPSPVVENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKYQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            complement(23676..24053)
                     /locus_tag="VXB91_001113"
     CDS             complement(23676..24053)
                     /locus_tag="VXB91_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HEV0470581.1"
                     /translation="MICQFIRDMLDLPAKNVTILEGSNIHVLPSMPYSAQDFYTSIDV
                     LAELDNGIQVIIEIQVHHQNFFINRLWAYLCSQVNQNLEKIRQREGDTHQSYKQIAPV
                     YAIAIVDSNYFSDDLAFHSFIVK"
     gene            24268..25245
                     /locus_tag="VXB91_001114"
     CDS             24268..25245
                     /locus_tag="VXB91_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEV0470582.1"
                     /translation="MLKLGVIGTGAISHHFIEAAHTSGEYQLVAIYSRKLETAATFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVTQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLADKQVLGADFNYAKYSSKMPDLLTG
                     QTPNVFSNRFAGGALMDLGIYPLYAAVRLFGKANDATYHAQQLDNSIDLNGDGILFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGNQVQLPIQQAPHT
                     MTEEVAAFAHMIQQPDLNLYQTWLYDAGSVHELLYTMRQTAGIRFEAEK"
     gene            25242..26324
                     /locus_tag="VXB91_001115"
     CDS             25242..26324
                     /locus_tag="VXB91_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV0470583.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTPIQTQLFEPLLAGENLLGVSQT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLVYMSATTKFDQEKIVPNTRTINLSDQKLDNIQHFYMQVDQRHRVD
                     MLRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILTVSLASDVNVKFRKIILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRMGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
     gene            complement(26388..27418)
                     /locus_tag="VXB91_001116"
                     /pseudo
     CDS             complement(26388..27418)
                     /locus_tag="VXB91_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT         8164 a         6219 c         4941 g         8413 t
ORIGIN      
        1 gatttacatt cataaattcc tccgtcactt tttattttaa aggattttag aattttttac
       61 aagatattat gctcaaattt aacattattt agctatttag taaagatagt ctttcaagga
      121 ttttgacaaa gcctgataac cagcaatact gaggtgcagt ccatcagttg tatattcttt
      181 tttgagttgg cctgcttggt ctgtcaaaca atcaaatact ggcacaaatt ccacctgcat
      241 ataggcagat gcaagctctt gataggcttg attccagttc tgaatttttt cattcgagcg
      301 gatatagact gcctgctggt actcctctct ctcattgaca ggcaaaatgg aaagcaattt
      361 aatctctgtc aatggataat cgcgagcaac ggattgaatg atagcttcga gattattgag
      421 agcctcattc acaggaacat cctttccgat atcatttgtc ccaatcagaa gaaaaatttt
      481 atctactgct ccaccatata gatgagcatc aaggttctct agtaacagtc ctgtctgata
      541 gccacgaatt cctcgattga caatcgtctt tgaagtccca aatagctcct gtagaggata
      601 atactcgaca atggaatccc caataaaaag aatgtttggt tctacaacag aaatgtgatt
      661 taggtgacga tacttagttt gaattttttc ttgttccttt aggagccaat tttctaataa
      721 ctgtactgcc acttcattct cctttttcta accagttttc caagacttga taaactcctc
      781 cttggctgtt ggctggtgct agagcagtcg ccacagcttt ggctttctca tcagcatttt
      841 ccatcgcata ggcaattcca gccatttcaa gcatttcaac atcattttca ctatcaccaa
      901 aagccatgat ttcttgggat ttcaagtccc agcgcttgag taattcctcc aagccccatg
      961 ctttatgaat cccagcttgg aggatatcaa tgcaaccata gccactggat acagctcgga
     1021 cacggccatc aaagagagca ttgatttctt ccaaaaccga actcaaacgt tcctcaccaa
     1081 caaccatgct catcttgagc acaccaccaa agaggtcaga tgttaattca tccacaaatt
     1141 gcatccgttg gtagaatttt tcaatcattt ctggagtcat aaaactttca agatctgtaa
     1201 aaatcgtacc ttccttgaca aaatcaccct tcatccccgt tacaacaaac tggtcctgac
     1261 acgctcgacc cttgaaatga gtcaaagcct tgttgacaat ggcgtcatcc catgtctgag
     1321 cctgaatcaa ttcattgttt tcaaaaatac gagcgccatt agcaacaacc agaaccactc
     1381 gatccaccaa gggactcagt agttgtctca tgcggtgaat ttcattgccc gtcgcaatga
     1441 caaaacgaat gcccctttga tccaactgat ctaaaatctt ttccaatcgt gggagatcaa
     1501 gctgacctct agcatccagc aaggtcccat ccatatctgt cgcaattacc ttaatcatca
     1561 tttactttcc tctggattca agctaatacc acttcaatcc cacatgttca ttcatttctt
     1621 tataggctgt atcaattcgt tccttagtcg cttcatctaa ctggtcacga tgactgccat
     1681 cctctataaa atcttccaaa atataagttt ggtaatgata caagggatat ccttctggtg
     1741 aaaaggttcc ctttggtgtt cgattgaccc aagtaggatg agctttagct gttccgatag
     1801 ttgtttttcc atccttcttc ttgatggtga catccatgag aacaccacgt tcagtccact
     1861 tagcattctc ttcatctccc atagattcaa ttcgttgatt ggaaatgaag ttccccattt
     1921 aatagacaat gagcttttta tctccatctt tttccaccgt ttcagatggt tcaacaacgt
     1981 gaggatgccc tccaaagata atatccgctc cccaatcaat catcttgtga taaagagctt
     2041 tttgttcttc agttggttcc aatcgatact caacacccat ctgaggcatg ataatggtga
     2101 tatctgcttc cttctctgcc cgttcaactt cagcctttat cttatcttcg tttaaatctg
     2161 aaagataacg attatagtct tcctgagaaa tatactgctc aattccattg aaaccatagg
     2221 aataggctaa caatgcaacc ttgatagcat tcacttcctt aatgaccagc ggagcctgag
     2281 cacgtggttc gtgcgtataa actccgattg gagtgattcc agctttctca ataatatcgg
     2341 ccattaaaat aactccctca atttgcgaat ccaaaatatg attatgagct aaatccagca
     2401 catgataacc tgcctcctta atagcatcca taacttcaac aggagcatta aagagaagat
     2461 aacccgctaa ataatgatcc ttattaatgg ttccttcaaa atcaccaata gctaaatctg
     2521 cttgcttgag ccaaggagtc acatactcaa aattttcatg aaagtcatag gtaccgtctt
     2581 cttttttagc tgaaaagaaa agtccatcgt ggtagagcaa atccccgtgg gccataattc
     2641 tggcagtttt ttcctcttcc tactcctgag acttttgctt agtcccctct tgagaaatag
     2701 tatctcgttt ttgactagtc aagggattcc ttggaagctt tcaaacaaca agaccaagcc
     2761 cattgataaa ccaactgcta gcaagagtat cgccacaaat cccttattgc tccacttgcg
     2821 ataactccta aaaagtttac caagcccttc ataaaacgaa aagctgaacc accctgattt
     2881 cgattttgtc ttctttgtat cttcgttctc cctactttct tatgcaagcc ttttcttttt
     2941 attatatcac agataagtat ttctttcaca attgaattga acttcctatc tattttctat
     3001 aaatcctaaa tgccataatg ctttcaattc ttgtcatttt gtgatatcat gtagaggaaa
     3061 tgaactaatc cacagtggct tattccaagt ataccacttg ggctttggca gtagctaact
     3121 gcactaaaca taatataagg agagaaaatg tctgcaatag aacgtattac aaaagctgct
     3181 cacttaattg atatgaacga tattatccgt gaagggaatc ctactctacg cacggttgct
     3241 gaggaagtca ctttccccct atctgaccag gaaatcatcc taggcgaaaa gatgatgcaa
     3301 ttccttaaac attcccaaga tcctgtcatg gctgaaaaaa tgggactccg cggtggtgtt
     3361 ggactggctg ctccccagtt agatatctca aaacgcatta tcgctgtttt ggtacctaat
     3421 attgttgaag aaggcgaaac tccacaggaa gcctacgatt tggaagccat tatgtacaat
     3481 ccaaaaatcg tctctcactc tgttcaagat gctgctcttg gcgaaggaga aggttgcctg
     3541 tctgttgacc gtaacgtgcc tggctatgtt gttcgccatg cccgcgttac tgttgactac
     3601 tttgacaaag atggagaaaa acaccgtatc aaactcaaag gctacaactc cattgttgtt
     3661 cagcatgaaa ttgaccacat taacggtatc atgttttacg atcgcatcaa tgaaaaagac
     3721 ccatttgcag ttaaagatgg tttactgatt cttgaataaa gaaaatcccg ttgcaagacg
     3781 gggttttgtg ttataataga ggcatgaaaa caaatgatat tgtctatggt gtccacgctg
     3841 ttaccgaagc cctccttgca aatacaggaa acaaactcta cctccaagaa gatctccgag
     3901 gtaagaatgt tgagaaagtc aaggaactag ctacagaaaa gaaggtgtcc atttcttgga
     3961 catcaaaaaa atctctctct gagattactg aaggtgctgt tcatcaaggt tttgttctac
     4021 gagtgtctga atttgcctat agcgagctag attacatcct tgcaaaaaca cgccaagaag
     4081 aaaatccact tctattgatt ctagatggtc taaccgatcc ccataatctg ggttctatct
     4141 tgcgaacagc cgatgcgacc aatgtttcag gtgtcatcat tcccaagcac cgtactgtcg
     4201 gagtaactcc tgtcgttgcc aaaacagcca caggtgctat tgaacacgtt ccaattgccc
     4261 gagtgaccaa cctcagtcaa accttagata aacttaagga tgaaggtttc tggacctttg
     4321 gaacggatat gaacggtact ccttgccaca agtggaatac aaaagggaaa atcgccctca
     4381 tcattggaaa tgaaggaaaa ggtatctcta gcaacatcaa aaaacaggtc gatgaaatga
     4441 ttaccattcc gatgaatgga catgttcaaa gccttaatgc cagtgttgct gcggccattc
     4501 tcatgtacga agttttccga aatagactat aaaaaagttt ccagtcatct gattggaaac
     4561 ttttttatga ttaactatgt tctgtaatga atttataggc ttcttgacca gcgatagctc
     4621 catctccaac cgctgttgtt acttggcgaa ggtctttcaa gcgaacatct ccaactgcaa
     4681 agataccgtc gactgcagtt ttcatgtggt tatctgtcac aatccatcct gcctgatctt
     4741 ggatattcaa ttctttaaca aaatcgctaa gagggtccaa accaacatag ataaagacac
     4801 caccgaaggc ttgttctgtc acttgacctg ttttcacatt ttcaaatacg actgattcta
     4861 ctcggttttc acccttgatt tcccttacta cagaatccca gataaagctg attttttcat
     4921 tcgcaaaggc gcgatcttgt aaaacctttt gggcacgaag ttggtcacga cggtgaacaa
     4981 tggtaacagt cttagcaaaa cgagtcaaga agagggcttc ttcaacagct gaatctccac
     5041 caccaactac caataaatct tggtcacgga agaaagcacc atcacacaca gcacagtaag
     5101 aaacaccacg actgttcagt tcttcttctc caggcactcc caaaggacgg tgtttagaac
     5161 cagttgctac gataactgta cgtgtttcat atgtttggtc atcagtcatc actttcttaa
     5221 aatcaccatg gtcttcgaca ttttcaacat aaccataaat gtgctcaaca ccaagatttt
     5281 caagtggttc aaacatcttt tcagccaatt caggtccact aatattagcg tatcctgggt
     5341 aattttcgat atcagatgta ttattcatct gaccacctgg cagaccacct tcaatcaaag
     5401 ctacttttag attgcttcga gcagcataca aggccgcagt catccctgca ggtccagcac
     5461 cgataataat agtatcgtac atatagattc cttctttctt gttgtaacta tctttattct
     5521 aactctttct tgtcaatcac gcaaggatta tgccttgaaa acaagaatta aactcataac
     5581 cgcaaaggat aatactggga caaccaagac tccaatcata atcatatcat agagatgggc
     5641 ttggcgagcc ctggctgtct tatcaactcc cgacatggct ctcagaccaa tccaaatccc
     5701 taaaaaaatc agaacaagga tggtggtcaa gatcaaactc tcgaaatata aagaaaatag
     5761 ttgcagtagc atgatttctc tcatttctat cttttttaaa gagtaaactc agctagtcca
     5821 actaactgag ttttccttta tctattatat caaatataag tccgtttgta actagcgaag
     5881 aattcttttg tccgctcttc tttaggggtg tggataatct catccggagt tccagactcg
     5941 atgattttcc ccttatctaa gaagagaatt ttatccgcaa cttgggctac aaaggacatg
     6001 tcatgactga ccaaaatcat ggtctgacct gacttagcag catctgcaat agacttttct
     6061 acttcaccga ccaattctgg gtcaagggct gaagttggtt cgtctaagag caaaacatct
     6121 ggtttcatag caagcgcacg cgctagggca acccgttgct tctgtccacc tgataaatgg
     6181 cgaggataat ggttttcacg gtccgaaagc ccaaccttag ccaactcttc cttggcaatc
     6241 ttagtcgctt cttggtcaga taatttcttg acaacaacca agccttcttt cacattatca
     6301 agtgctgttc ggcgttcaaa taaattaaac tgttggaaaa ccatagacaa cttacggcgt
     6361 agggcaagga tttcttcttg agtgatttta gaaaaatcaa ctgaaaaacc atcaatctga
     6421 atagagccac tgtcaggtgt ttcaagataa ttgagactgc gaagaaaggt tgattttcca
     6481 gctcctgaag aaccaatcaa ggctacgact tctccttttt gaatatccaa gttcagatga
     6541 tccaagacag tctgtcctga aaaggatttg cttaaattcg aaatcttaat cattaacgaa
     6601 ggtctccttt cacatctgtt tgcactgtat caggtgcaga aatagccatt tttctctcga
     6661 tgaaacgacc gaggctttca attccgatat tgactaccca ataaacaagg gcaacggaga
     6721 tgaagcgttc aaaatagcga taatcagctc cacctagaat ctgagcttgg gcaaagactt
     6781 ccacaacacc cgcactaaaa gctagagatg ttcccttggt caaaccgatg agggaattaa
     6841 tcaaggttgg agtagctacc accgctgcat taggaataat cactcgtcga taaacttgcg
     6901 ctcgggtcat acccagactg cgtgccgcct caatctcacc aggattaact gagagaatgg
     6961 ctgcacgaat ggtttcacta gcataagctg cctcattaaa ggcaaaagcg acaatcgcaa
     7021 aagctgcagc tggaatcgca ttgatattga gaccagttcc ccattgctga ttgagggctt
     7081 tcaaagccaa agggattccg tagtaggtca acatgagttg caccaaaatc ggtgtccctt
     7141 ttaagaaact aacaaagaag gcctgcaagg gatataaaat cttgacacga ttgatcttca
     7201 caatggcaaa aagaagcgcc aaaaccaagc caaaaagggc accaccaatt gtcaacataa
     7261 ttgttgttgg aagttgttgg acaattctag ggattccatc aaagaccgaa cgtaggctaa
     7321 acagcttgcc atccggaatc aattgcatca agttttggta ccaatctgat gctaaaatcg
     7381 ttgtaacatt cataaaaaca tcctcttctg ataatgattc attctaccat gcttctgccg
     7441 tcaatgaaat tatttgctac ggtcagatac agactttgtc tacctactag tttatcatac
     7501 tttgaaacag ggaagttata tattttatct atcaaagaga tagataaaaa ctatttcagt
     7561 cccagttctt cataagattt tcgataaccg atttgcttaa cagttccatt ttctactaaa
     7621 atgggccgtt ttaacaacat accgtcactt gctagcaact cagccgcttc ttggtttgac
     7681 aaacttccta ccttatcttt tagccctaat tcacggtatt tgataccact ggtgttgaaa
     7741 aattgcttca attcaaatcc tgaggtttct agccaattca aaatgacttc ttggctaggt
     7801 gtttcttcca cgatatggac ggctttatag tccacaccta attgatttaa ttcttgtttt
     7861 gcttttttac aagttgaaca tttggggtat tcgataaatt ctaacatgtg cttctccttc
     7921 tatttgttta tatctttaaa atctacgcct tcatgctcca agagccaagc tttcttttcc
     7981 actcctgcag catagcctgt cagacgcttg cctgctccca acacacgatg acaaggtact
     8041 aggatagacc aaggattgcg tcccactgct ccaccaattg cttgagcaga agccacttgc
     8101 aggtcttgag caatttgtcc ataggtcact gtctgaccat aaggaatgcc ctgtaaatag
     8161 tcccaaactc tcttttcaaa attcgttccg attggcgcca agagcaagtt ggataaatcc
     8221 tgaggcttgc ctttaaagta atcatctaag caagcaataa ctgggtctaa aataggatga
     8281 ctaacaactt cttctatcgt ttcatctcct agtcccctct caaaatgctt ctgctcctga
     8341 acccaaattc catacaaata atggtcatca gctacaagtg atagaatacc aattggtgag
     8401 gagtagagta tttttacata cttcttttgc attatttctt taatttttga taggccaagc
     8461 gttcgccatc tactggcacc ttaccaactt gtttaaaacc aagtttttca aaaatatgtt
     8521 gcataacctt gttttcagca tgcgtatctg agcgaaaatc aagataatca aaaccttcaa
     8581 tcaagccctc taagaaggtt tgagcaactc cttttccctg cacatctgct gccacagcaa
     8641 tacggtgaaa gactagatac tctgactctc cagcttgcca gtttccctca taaatagctt
     8701 cataggcctc ctctggactc ttggtcacag cagcataggc tagcagttct ccctcttcca
     8761 aggctacgta ggcttgccct gagatgatat catcgataat aacatctgca tttggatagc
     8821 cattttgcca ctggtcacta ccagcatctg ctaaacattt tttggcatcc tccatcacct
     8881 gcatgatggc atctacttca tttggaaaag ctaaacgaat ttccatcttt tttcctcatt
     8941 tctgactagt ttctcccatc atagcataat ttaagtattt ctacaagcag ttaaaacttg
     9001 actttgtgtt tttgttattt tataatctag ttatcaaaac tatataaaaa ggagttaaaa
     9061 atgaaaacta ccttttccta cccaaaatgg gcagaaattc caaacattga cctctatctg
     9121 gaccaggttt tgctctatgt caatcaggtc tgcgccccta tctctcctaa taaagacaag
     9181 ggcctaacag catctatggt caacaattat gtgaaaaatg gttacctgac aaagcctgac
     9241 aaaaaaaaat accaacgcca acagattgcc cgtttgattg ctatcacaac cctcaagtct
     9301 gtattttcta ttcaagaaat agcccagaca cttaatactc tacaaactca agcaagttca
     9361 gaccaactct acgatgcttt tgtggactac atgaaccaag gaattgaccc agctaaccct
     9421 attatccaaa ccagctgcca aaccgttaaa ctctatcatc aaactctaga cttaatcgat
     9481 catactcaag aggaggtaat ccaatgaaca ctagtcttaa actcagcaaa caactcagtt
     9541 ttggagagga gattgctaat agcgtgaccc atgctgtggg tgcagtcatc atgcttatct
     9601 tgctgcctat ttcatccatc tatagttatg aagcacacgg atttttatcc tctatcggcg
     9661 tttccatttt cgtcatcagt ctctttctca tgttcctatc atccaccatt tatcactcta
     9721 tggcctatgg ttcgacccac aaatatgttt tgcgaatcat tgaccattct atgatttacg
     9781 ttgccattgc cggatcatac acgcccgttg tcttgacctt gatgaataac tggtttggct
     9841 atctgattat tgtcatccaa tggggaacga ccatctttgg tattctctat aaaatctttg
     9901 ctaaaaaggt caatgagaaa tttagccttg ctctttacct gattatgggc tggttggttc
     9961 tggctatcat tcctgccatt atcagtcaaa cgacacccgt tttctggagt ctcatggtaa
    10021 ctggcggact ctgttataca gttggagctg gattttatgc caagaaaaaa ccttatttcc
    10081 acatgatttg gcatctcttt atcctagctg cgtccgcact tcaatacatc gctattgttt
    10141 attacatgta aaaaagttga gaaattcaat ctcaactttt ttctttacac atattgataa
    10201 agtactggtg caagcgcaca tcatcagtca attctggatg aaaagaactt accaacatat
    10261 ttttttcttg ggctgcaaca atttgattgt tcactgttgc taaaatttct acaccctcac
    10321 caacactact gataatcgga ccacggataa aggtcattgg aatcttgcca actcccttac
    10381 attctgcttc cgtgtagaaa cttcctaatt ggcgcccata agcattacgc tcgaccacca
    10441 tatccatagt tcctagatga ctctctttct gagaagtgat ttccttagcc agcaaaatta
    10501 agcccgcaca ggtcccaaac actggtaagc cagatagaat ggcttctcgg atgggaagta
    10561 gcatgttctg gtcacgtaag agcttgccca tggttgtaga ctcaccacca ggcaaaatca
    10621 aacccgacaa gtcactctga tcttgctgaa aatcatctag atttctgagt tctacactct
    10681 cgacacctaa ttgatctagc acttttgcat gttctgcaaa ggccccttgc aaggccaata
    10741 ttccgatttt catctatttt cctcgttcag ccatgagaat ttggatttca ttttcattaa
    10801 taccaaccat ggcttctcct aaatcttcag agatttgagc taggatttga ggattacgga
    10861 agttagtcac agccttaaca atggcactcg ctcgtttaac aggatctcct gacttgaaaa
    10921 tacctgaacc gacaaagacc ccctctgccc ctaattgcat cattaacgca gcatctgctg
    10981 gcgttgcaac acctccagca gcgaaattta caactggcaa ttttccatgt tcatgaacat
    11041 attggaccaa ttctacaggg acttgcaaat ccttggcagc aacataaagc tcgtcctcac
    11101 gtaagttttg aatgcggcga atttcctgat tcatcatacg catatgacga acagcttgga
    11161 cgatatcccc tgtccctggt tctcctttgg tacgaatcat ggaagcacct tcagcgatac
    11221 gacgcaaggc ttcacccaaa tccttagcac cacagacaaa aggaacttgg aattctttct
    11281 tgtccacatg gaaacggtca tcagctggag atagaacttc actctcgtcg atataatcaa
    11341 tttcaatagc ctctaaaatc tgagcttcaa caaaatgccc gattctgacc ttagccatta
    11401 ctggaatact aaccgcttct tggatttcct taatcatctt tgggtcgctc atgcgggaaa
    11461 ctcctccagc tgcacgaata tcagccggaa ttcgttccaa ggccatcaca gctgccgcac
    11521 cagcagcttc tgcgatacga gcctgttcag gattctgcac atccataata acaccaccct
    11581 tgagcatctg tgccaagttt ttatttagtt cataacgatt ttcagtcatt tgttttatcc
    11641 tcatcatttg tattggtagc taccttttca ttttaagtca gaacagaatg aagcacaaga
    11701 taaaaaaact ataattgtat ggggacaaat tagctaaaaa ctatctgacc ttaacttaag
    11761 gccagatagc tcattcattt ttatttttca gccgtaaggg cagccattgt gatgtagttg
    11821 tatggtttgt tgaagtgtgg caagaagaag aggtctgtca atgccaattt atcaattgtc
    11881 acatgctctt ggatagcaag tgagaacatg tggattccca tgctaattgc aatatcatgt
    11941 gaaaccattt gggcaccaag aatttcacgg ctatctttgt caaagacaat cttaattgct
    12001 acttcatggt tgtcatgttt catgaattct ggtttttgaa gatcgttaaa gcctgtttca
    12061 gttgcgttgt aaccagcagc tttcgctttt tcaagagtca aaccagttga aaccatgtga
    12121 agaccgtaga ttgagatacc atttgaacct tgaacaccga ttccttccaa ttcatgtcca
    12181 caagcattgt aggcaccaac gataccagtg cgaacagcat ttgaagcaag agcgatatag
    12241 cttgtatctt tacgagcatt gtcataaaca gtcgcacagt caccaacagc gtaaacgtct
    12301 gggatagatg tttcttgttt cttgtctaca aggaaggcac cgttgcggaa gagttcgatc
    12361 ttaccacctg caagggctgt gtttggacgg aaaccaactg caaggataac catatccacg
    12421 tcaaagcttt ctttgtcagt aatcaagcgt tcaactttac cgtcaccttc gattgcttta
    12481 acagtttgac ctagagccaa gcggatgttg tgatcttcca agttcttcgc catcatttgt
    12541 gtgaagtctt tgtcatagta accgttcaag acagtatcaa cgatatcaac aaggacaact
    12601 tcttttccaa gacgttcaaa ggcttcagca agttcaacac cgatgtaacc accaccaaca
    12661 acggcgatac ggtcgaggtg ttggctcttg tcagaaagtt tattgataac ttcttcagca
    12721 ttttggtaca atttcacgaa ttgtacgttt tcaagagttg ctttaaattc gcggtttcct
    12781 ttaacaattt caacaccttc gattggtggc aagattggtg tagaacctgt agcgaaaatc
    12841 aatttttcgt atgattcttt gtgctctttt ccttcaactt ccgctgtaac tactttgtta
    12901 tcatagtcga ttgaaagaac aggtgagttc atgtaaactt tagcaccttt agcttccaat
    12961 ttttctttat cagaatagaa caagccttca gcaccgtcaa tttgttcacc aatccaaaga
    13021 gccattccac atcctaggaa agagatgtta gagttttggt caaatacaac aatttcgttc
    13081 tcatttccaa aattatccaa catggtattg atacatgctg taccagcgtg gttagcaccg
    13141 actacaacga ttttactcat aaaaatttcc tgccttcatt ctaaatttac cttactagta
    13201 taccatttac cgttagcgtt tacaaggggg gtactattat ttcagcattt tttatcaaaa
    13261 ataattcccc atttatcctg ttttcaagcc tgatgaattt tatgagcata tttcttgact
    13321 ttttccaaat tttgtttgtg aaaattctaa ctttatggta ttataataac atgaaaatga
    13381 aatgtaaggg cttcaattta gatgattatt tgatattaca acttattttc tataagagaa
    13441 aggagttggt agcttgactc ttcgttcaca ttctgaacgg ctaatgggga ctactatcac
    13501 tatttcatta gtggatgagc aagccgatat ctttctccaa aaatcctttg acttgctcaa
    13561 agaacttgaa taccgcttca acgccaatag tcaagaatct gagttgatgg aaatcaatta
    13621 tcaagcagga atagcccccg tcacggttca tccagacctg tttgagctga tttcacttgg
    13681 gttagagcat agcctagcgc tctctagcca cctcaatatc agcattggtc ccttaattca
    13741 aacctggcgt atcggttttt cagatgccaa ggtcgcccag cctcaagaaa ttgaatcggt
    13801 gctgcctcta atcaatcctc atggtatcga gttagattct tctacttcta ctgtgttttt
    13861 aaaacagaaa ggaatgaaga tcgatctagg ttgtttagcc aaaggataca gtgcggataa
    13921 ggttgcccaa tttcttagga aagagggggt gacttctgcc ttgatcaatc tgggagggaa
    13981 tatcctgacc attggaaaaa atcaggcaag aggggataac ccatggcaaa tcgggattca
    14041 agacccagcc aatcctaggg gaaatcattt aatgaccatc cctgttgtca ataaatctgt
    14101 cgtgacttca ggcatttatg aacgtcacct gaccgtcgat ggacaagatt accatcacat
    14161 ttttgacagt caaacaggat atcctgttga aacggaacta gcgagtctaa caatcatctc
    14221 tgataaatca gtcgatggcg aaatctggac gactcgactc tttggagaaa gacctgcttc
    14281 tatcctctgg caagtcgaaa gtttggaggg catcgaagtc atcctcatcg ataaagaagg
    14341 ccacctaagc tgttcttcag gaattcctac tctatagaga caactgtttc aatggaattt
    14401 taaaattgta ttatgtaaaa agagaaagga aatctcatgt taaaacttat tgctattgtt
    14461 ggaacaaatt caaaacgttc tacaaaccgt caattgcttc aatacatgca aaaacacttt
    14521 actgacaaag ctgaaattga acttgttgaa atcaaggcca ttcctgtctt caacaaacca
    14581 gctgacaagc aagtacctgc tgaaatattg gaaattgctg ctaaaatcga agaggcagat
    14641 ggcgttatta tcggtactcc tgagtatgat cactctattc cagctgtttt gatgagcgct
    14701 cttgcttggt tgtcttatgg tatttaccca cttttgaaca aaccaatcat gattacaggt
    14761 gcttcttacg gtacgcttgg ttcatctcgt gcccaattgc aacttcgtca aatcttgaat
    14821 gctcctgaaa tcaaggcaaa tgttcttcca gatgaattct tgctctcaca ctctcttcaa
    14881 gcatttaacc caagtggcga cttggttgac cttgatgtta tcaagaaatt ggatgccatc
    14941 tttgatgact tccgtatctt tgtaaaaatc acagaaaaat tacgtaatgc acaagaatta
    15001 cttcgcaaag atgctgaaga ctttgactgg gaaaatttgt aagataggag accaaaaaga
    15061 atgaaatttg ttggacttgt tggatcaaac tacgatcaat catataaccg taagctcttg
    15121 gaatttatcc gtcgctactt caaactcaaa tttgaattag aagttcttga aattgacgaa
    15181 gttccaatgt ttaaccaaga tgaaaaatgg gatgaaagtt tccaattacg ttatttatat
    15241 aacaaaatta ctcgtgcaga tggtgttatc attgctactc ctgagcataa ccacactatc
    15301 tcagcttcac tcaaatctgt acttgaatgg ctttcatacg aagttcatcc atttgaaaac
    15361 aagcctgtta tgattgtggg tgcatcatac tatgaccaag gaacatcacg tgctcaagtt
    15421 caccttcgta aaatccttga tgctccaggt gttaatgcct acacgcttcc aggtaacgaa
    15481 ttccttcttg gtaaagctaa ggaagctttt gataacaacg gaaatatcac caacgaaggc
    15541 actgttaaat tccttgaaac ttgcttagat aactttgtta aatacgtagg agtcgtttcg
    15601 aaattgaaaa aaccaaaacc aatcgaatca gaagacttgg attgtggaaa accaatcgct
    15661 acaaccatca cagaagttga ccctgacgat ccagaatggg tagaaaaagt tgcagcattc
    15721 actggtgctg tttctggtga tacctatgtc aaattggacc acggtatcct aacagttaac
    15781 caaattgata tgttcttgaa agctatgcca tttgaattga catacgctga cgacaacaac
    15841 caattcctct actacaacaa cgctcaccaa gatccagaca ctatgttcgc taaacgtgta
    15901 ccacctcaat caggtagccg tatgtcgact gttcatggtt ctcttccacc agcacgtatg
    15961 aagaacgtag agtgggttat cggaacactt cgcaacggaa accaagaata cgtccgtacg
    16021 atcgttccag gttctcctgc aggtgttatc aacactcaca actaccaagc aatgtactat
    16081 cctgatggat catacgctgg tatcaatgaa atcgtcttta acttccaacc atggcttgac
    16141 tggtacctaa aagagactgg tcaacgtttg gtgggtggta gcggaccatt tgctcctgct
    16201 gccggaggtc atggagacgc cgatgctact tctagcgctt ctgattcagg ggatgctgga
    16261 ggccacggtg gtgacgcaga cgctacagcc ggtgcaagtt actaatgata gtttttagga
    16321 actattatgg ttcctttttt agcgaaaaaa gactagcaaa cacaaactgc tagtctcttt
    16381 gttatcgttt catctatctt tgttaaaaga aagaatacat atactcaatg aaaatcaaag
    16441 agcaaactag gaagctagcc gcaggctgta cttaagtacg gcaaggtgaa gctgacgtgg
    16501 tttgaatttg attttcgaag agtattatta tgaatttgga tcatcaagac tacggccatg
    16561 taatcctttt tcacgttgta cttggcgtag tttttctggt gtaacatcgt ttccttcttc
    16621 gtccacaatt ttgattcctt caatgtggtg acgaacagcg cggcgataac cttcgatgta
    16681 ctcctcacgt agtttggctt gttccacttt ttcttctggt gttaagcctt ctgttttttt
    16741 ctttttagca agctcattga tacgagcaat ttttttcgga tccatttctt ctcctttgta
    16801 ataagataaa gtccgtttat caaattttat ttagtgttaa tttggttaaa acaagcaaac
    16861 ttagctgctt tcttggttag ttgtgacaag attgccaaac gattttgacg gacagcctga
    16921 tcttcagcca ttaccatagt attttcaaag aaagcatcaa tgactgggct aagcgcaaaa
    16981 agttgtttca attgctgact tgcaggtcct gataaaatga gtgtttctac tgcttctgcc
    17041 aaagcttttt cttggtcatt ctcaaatagt gctgaatcaa ccgtagcaac cccttctgcc
    17101 ttctcggcca ggttaaaggc acgagaaagt gattcaacag atggtttaaa atcttcttcc
    17161 ttgcttactt ctacgagagc acttgctgct tccaacatat ctgccacaac aaagtttgaa
    17221 cctgcaagaa ctgcttcctt gatatctttt ggagtagagc ccatcatctt atcaacacga
    17281 gccttgataa agtccataac ctctgcttta ttttcataag tcaaactgtc aaatttcaat
    17341 gcataaaggc tatcaatcag ctcatccata gcaatgtgcc aaccaaaggc atccaagata
    17401 cgaaccacac cttgagttgc acgacgaagg gcataagggt cattagaacc tgatggaatc
    17461 aatcctactg agaagaaact caaaatcgta tccaatttgt ctgcaatggc tagaactgcg
    17521 ccgaccttgc tctctggaag ttctccttca gctgatgtag gcatgtagtg ttcacgaata
    17581 gcagctgcca ccgctggagt ttcaccagca agaagggtgt atttttcacc cataattcct
    17641 tggagttcgt caaattcacc aaccatacct gtcaacaagt caaacttgta aatggctgct
    17701 gcacgagcaa ggtcaactgt ttcatccact gacaaactag ctttttctgc caaaagtaca
    17761 gtgatttgac ccgtacgaat catgtgttca cgaagggaac caatcttctc atggaaggtg
    17821 acattgttta atttttcaac aagatctgaa atcaccaatt tttggtcttc acgccagaag
    17881 aattctccgt cttccaagcg ggctaccaag actttttcat ttcctttgat gacatttttc
    17941 aaacgctctg cgtttccgtt acgaacagaa atgaagtttg gcaagagttt tccatcttga
    18001 tcacgaacaa caaagtaacg ctggtgttcc ttcatagaag tcaccaagac ttcttctgga
    18061 acttcaaggt atttagcatc aaaacttccc atgaaggcag ttgggtattc aaccaaattc
    18121 aagacttcat tcagcaaatc cgcatcaatt tcgatacgta caccatgttt tgcctcaatt
    18181 tccttgattt ggtcaacaat catttgctca cgttcacatg gatctgcgat tacaaactgc
    18241 ttacgaaggt cttcttcata gctcaatgct gactgaatct tggtttcttg tcccaaaaaa
    18301 cgatggccac gactcacacg acttcccttg atatcaagga aatccaagtc aaactcttgc
    18361 tcatccaaga gaacagttaa agtgtgaaca gggcggatgt attcaaagct atttcccgcc
    18421 cagtgcatgc tgacagggaa agtcagtgac ttcaagacat ccacaatgcc tggaacaatg
    18481 gcttcaactg cttgaccaat ttcttcctta gtgacataga catattcttc acccttgatt
    18541 tcacggaatt cgatatcttc aacagtcaaa cctttcccac ggacaaatcc ttgagctgct
    18601 ttggtgaagt ttccatcact atctaaggca attttctttg ctggaccctt gaaatcttct
    18661 gttaaatcag actgtttgtc tgcaagacca gttacacgaa cagccaaacg acgtggtgtt
    18721 gagaaagttt gaatggcttc aaaagacagg cgttttccct tgaggaaggc tgccattttt
    18781 tcgcctagtt gtttttcact tggcgtaaca acataggctg gtaattcttc aagaccgagt
    18841 tctactaata agttttttgt catgtttttt cctttacatt ttcttcaatc ttttttgata
    18901 tgcaccttag gtactgggga cgtcgctaac taactctgtg agtctgtatg gaaatccaat
    18961 gctaaattta tcaagatttc caacaatctc atcaaagtgg atttagctga ctgatttttg
    19021 aacctaaggt ttcaaaaatc cccacataac agtacagcgg tgcatatccc tctagcaagt
    19081 cttcgacttg cctctaacga ttttagagta cagtattact cactattctg cgtcttctgc
    19141 taaaagttta actcgtgttt cttcatccaa aagtgggtaa cctaggcgtt tgcgttctgc
    19201 aacaaaggtt ttggctacaa cacgggccaa gttacggata cgagcgatat agcctgcacg
    19261 ctctgttaca gatacggcac cacgcgcgtc aagcagatta aaggtatgtg aacatttgag
    19321 aacatagtca taggcagggt gtaccaagcc ttcttctaat gcacgaccag cttctttttc
    19381 aaacttatca aaattttcaa gcaacatttc ttggtccgaa atttcaaatg aatattttga
    19441 gtgctcatac tcaggctgga taaagatttc tccgtatttt acaccatcag cccactcgat
    19501 atcatagaca gagtctactt cttgaatgta agaagccaag cgctccaaac cataggtaac
    19561 ttccgcagtc acagggctag ttgccaatcc accgacttgt tggaaataag tgaactgagt
    19621 gatttccatt ccgtcaagcc aaacttccca accaagacca gctgaaccag ttgatgggtt
    19681 ttcccagttg tcctcaacaa aacgaatatc gtgctccaaa ggattgattc ccaatttttc
    19741 caaagactca aggtaaagtt cttggatatt tgatggagaa ggcttcatga ccacctggaa
    19801 ttggtggtgt tggtagagac ggttagggtt ttccccataa cgaccgtcag caggacgacg
    19861 tgatggctct acataagctg cattccatgg ctcaggtccg atagcacgaa ggaaagtgta
    19921 aggactcatt gttcccgcac ctttttcatt atcataagcc tgcataagca tacaaccttg
    19981 gtcattccaa aattgttgca aagtaaggat gatttcctgg aaagtcaatt tcttagacat
    20041 tgtttactcc tttagttttt atatttcttt ttcaattaat ttctgctgaa caaaccaatc
    20101 taacaaggga aaagtttttt ctgtatttgc ccataaatga taagaatcta agaccgcttg
    20161 tacactacct aaattttcta ccaacttatc tactgtcaaa aagctgcgcc agtattcata
    20221 aaaaatactt gcatagttct tatcataagt cgaagaacca aaatcattca atgaatgcca
    20281 accatacttc ttctgaaaaa gttctacgag agattgatta caaatttttt ccgcttgaaa
    20341 ttcctcttct gtcaagaaat acttgcgact aatatattca accatcccct cttcgaacca
    20401 gatataagag tcataaccat caaaatcatc taaaaaatgc tccgaccaat gagctaactc
    20461 atgtcctaca atctgtaaga ggaaattttc agataaagaa tgatagtgac tttctattgc
    20521 ttgagtttgc tcagaacact cgtagtccat caattgatac aaatacaact ctttccaaac
    20581 agctaaatca ggcgccataa ccattcgtct attatttgta taggctggaa cagcgctttc
    20641 cctaataatc tgtgtagcag cattaaaatc tgaccaaata acggcttgcg gtaaatcaca
    20701 gactgcaagt tcattcttta aaaaagattg ataatctttc aacttttcag tatttcttac
    20761 tacaaaatca cgaaatgtag ctagttgact atcgtctttt acaagataaa ggttgtccac
    20821 ggctctcctt tctttcacac aatagactga ataagcaaaa gaaccacatc tgacaatcct
    20881 aggttgattt aacctagggg cgtcagaaac gcggttccac cctaatttat tacttcattg
    20941 tttttgaaaa tactacagaa agcgccagct cattattttg ccctacttgg ctcccactgt
    21001 cccaagctcg cttgaagaac gccataagac tttctttcct gctgactatt atatcaaaaa
    21061 ttagaataat gtacaattct ttttatgatt ttctagaaat ccacatcatc aactcgtgga
    21121 gcccccgact gaacagcagt cgtttttaag gtttctctct cctcatgact cagttcaatt
    21181 ccaaaacaat caagattagc ttgaatacga gaggttgtga cagattttgg aagtggtaaa
    21241 aatccttctg ccaagctcca ggccaaggct atctgagcaa ccgattttcc gtgatttgct
    21301 gcgatttctt ggacttgctt gctatcaaac agttctcctt gtccaaaagg cccccaagct
    21361 tccaataaaa ttcccttttc acgacagtaa gctacgactt cctcttgata cacacctggc
    21421 gccaagcgaa cttgattgac cgcaggaacg atagttgcag tttcaagcaa ggcatccaaa
    21481 tgatggggaa gaaaattgct aacgccgata gcacggattt tcccttcttg atagaggtct
    21541 tccatcgctc tccaaacttc cgcattgcga gttttccatg cgtcattttc tctgagcggt
    21601 tttgggttcg gccaatgaat caaatacaaa tccaaataat ccaagcccag tttttctata
    21661 gatttttcca aagcttgacg agtttgctca taggtttgct gactattcca aagcttggta
    21721 gttacgaaca tttcttcacg tggaactccg ctatctttga ttgcttgacc aacactttct
    21781 tcattctgat aaatcgccgc cgtatcaata tgacgataac cagccttcaa ggattctaac
    21841 actgcacgat aggcttcttc tccatcctta gccttaaaag ttccaaatcc caatactgga
    21901 atttctactc cattatttaa ttgataggta ttcatatgct tctccttcta tatttattca
    21961 tcaattatag cataaaacat tttttaagta gtactatctt ctgtaaaaaa taagtctgtc
    22021 aaatatctaa cagacctatt ttttcttgct tattcatcac gactatagta cagctcatga
    22081 gcttttaggc gagtattgag catctctggt atggtcacaa aggtataacc ttgatttttc
    22141 aaatactcaa tgacccttgg caaggcattg actgtcggac tgtgaatatc atgcatcaaa
    22201 acgatagagc cgttagctac ttgatgctga atttctgtca aaatagatgc ttcattttta
    22261 ctcttccagt ccagactatc cacatcccac atgataaagc tcaaatccaa gctattgcga
    22321 atatcatctg taatagcacc ataaggtgga cgcatgagtt tagaactaga acccagcact
    22381 ttagttagca catcctcagt atcagtaatc tgctttttag cttcatcaag agagagttgc
    22441 gagagaatcg gatggctcca actatggttt ccaacaacat gaccttcaga ttttatcctc
    22501 ttcaccaagt cctcattccc agaaacattt ttcccaagca caaagaaagt cgctttaata
    22561 tcatatttag ctagggtctc taatacctgc ggggtcgttg ctggatttgg accatcatca
    22621 aaggttagag cgacaacttt ttgatatttc ttatcaaagt aagattggta caaggccgca
    22681 tctttttcga gtaagtacga agattggata acatcaaaga aagcagatac tggcaaggct
    22741 atctcttcta aattttcaac cacaggactt ggataaagga taatctgact atccttgtaa
    22801 tcaaaattcc atgcagacaa gtcttggtca gagaagtttt ttacaatctg ctcactctgg
    22861 tcttgctcta tttttttatc ctctatgaag gaggtcaact cttttatcag ctgttcctta
    22921 gccttactag catctgaaaa cagttggtca agtgtaaaag gttgcccatc ttctgttaag
    22981 tgaacctttc ctagactggt cttttcagtc tcttcaacct taaaagcaac taaatcatag
    23041 atttgtttgg tcacattacg attaacgact ccctttaaac ctgactcttc ttgctctgta
    23101 tagtagaaaa caagattgtc cttactttct agcttgtcct taacatcttg atttatcaac
    23161 tccctaacag aggaaatcac tttctcccct tggagaggat aataggcaat cacttcggct
    23221 tgcccctgac gaaaatgctc cttctgattt ccctcactca attgatcatc tttctctttt
    23281 ttgagcgatt caatcttttg ctcaaaactt ttttgctggt agatcttaaa agcaataaat
    23341 ccgcctaata ggcaaataga aattgctaaa ataccaatca aagccaataa tacatgtctc
    23401 gttttcccgt gtctgccacg tcctagtcta cttttattca tatttatatc ataacaaatt
    23461 tgagcaataa tttcaatgat acaatttggc aatccacaat tcctctagca agccaaagca
    23521 tcttacatca actccaacat ccgtatctgt agagattatg tagttttcta tctatggaat
    23581 ttctagtaga ttgaagctag aatagtagac ctatacttct aaaacattgt tagaaatcga
    23641 tttgattgtc ctgatcgatt tgtcctgttc tcatttcatt ttactataaa actatgaaaa
    23701 gctaggtcat ctgagaagta attactatcg acaattgcga tagcgtatac tggtgcgatt
    23761 tgtttgtagc tctggtgggt atcaccttca cgttggcgaa ttttttctag gttttgatta
    23821 acctgactgc acagataagc ccataggcga ttgatgaaaa aattctgatg atgaacctga
    23881 atttcgatga taacttggat tccattatct aactccgcca agacgtctat actagtatag
    23941 aaatcctgcg ctgagtaggg catggaaggc aagacgtgaa tgttacttcc ctccaaaatc
    24001 gtcacatttt ttgctggcaa gtccagcata tcgcggataa attgacaaat cattagttgg
    24061 gctgataccc ggatgtctga gaatcctcct tttcctcctt ctattatagc acatttttaa
    24121 atctaggttt gctagattct atgcttctat ctatttattc ggaaaagaaa gctaatagct
    24181 tatttgaaat tttctcctct ctgttggata gtcccgtcta tctatgttat aatgaaagaa
    24241 ggatttaaaa tcggaaaagg agtatttatg ctaaaattag gtgtcatcgg aactggcgct
    24301 atcagccatc atttcataga agcagcccat accagtggag aataccaact ggtcgcaatc
    24361 tattctagaa aactagaaac tgcagcaacc tttgcttctc gctatcagaa tatccaacta
    24421 ttcgatcaat tagaagtctt cttcaaatct tcttttgatt tagtctatat cgccagtcca
    24481 aactccttac attttgctca ggcaaaagct gccttgtctg ctggtaaaca tgttattctc
    24541 gaaaagccag ctgtcactca accacaagaa tggtttgatt tgattcaaac agctgaaaaa
    24601 aataactgtt ttatctttga agcagctcgt aattaccacg agaaagcctt tactactatc
    24661 aaaaactttt tagcagataa gcaagtgtta ggagcagatt tcaactatgc caaatactct
    24721 tccaagatgc ctgacttgtt gactggacaa acaccaaatg tcttttcaaa ccgttttgct
    24781 ggtggagccc tcatggattt ggggatttat cccctctatg ctgctgttcg tctttttgga
    24841 aaagccaatg acgcgactta ccatgctcaa cagcttgaca atagcattga cctaaatgga
    24901 gatggtatcc tcttctaccc agactatcaa gttcacatca aggctggaaa aaacatcact
    24961 tccaatcttc cttgcgagat ttatacaaca gatggaacct tgactctcaa cacgattgag
    25021 catattcgct cagctatttt taccgaccac caaggaaatc aagtccagct tcctatccaa
    25081 caggctcctc atacgatgac tgaggaagtc gctgcatttg cacacatgat ccagcaacca
    25141 gatctgaatc tctaccaaac ttggctgtat gatgcaggct ctgttcatga gctactatat
    25201 accatgcgcc agactgctgg cattagattt gaggcagaaa aatgaaaacc aaactaccga
    25261 ctgaatggca agaactgagt gaccaactcg gtttccaaga attcaccccc attcaaactc
    25321 aactatttga gccccttctt gctggagaaa acctcctagg agtgagccaa accggaactg
    25381 gtaagaccct agcgtatctc ctaccaagtc ttctcagact acaaaagaaa aaagcccaac
    25441 aactcttgat tctagcacca aacacggaac ttgctggaca gatttttgat gtatgtaaaa
    25501 cgtgggcaga agctatcgga ttgactgctc aactcttcct ttcaggttca agtcagaaac
    25561 gacaaattga acgccttaaa aaggggccag aaattctgat tggaactcct ggccgtatct
    25621 ttgaactcat taaacttaaa aaaatcaaga tgatgaatgt ggaaaccatc atcctggatg
    25681 aatttgacca attactagat gattctcaga ttcactttgt agaaaaaatc actcactacg
    25741 cacctcgtga ccaccaactg gtctacatga gtgccacgac caagtttgac caagaaaaga
    25801 ttgtgccgaa tacacgcact attaatctct ctgaccaaaa attggacaat atccagcatt
    25861 tctacatgca ggtagaccaa cgtcatcgag tggatatgct acgaaaactg gctcatgtag
    25921 aggatttccg tggtctagtc ttcttcaata gcctgtcaga ccttgggaat gccgaggaaa
    25981 aactacagta tcgtgatata ttgactgttt ccctcgctag tgatgttaat gttaaattta
    26041 gaaaaatcat cttagaaaag tttaaagata accaactaac cctgcttctt gcaactgacc
    26101 ttttggctcg tggaattgat atcgatagcc tagaatgtgt cgtaaacttt gatattccta
    26161 gagatagcga aacctacaca caccgtgctg gccgtactgg ccgtatgggc aaggaaggat
    26221 atgttattac tctcgtcact catccagaag aaatcaaaaa acttaaaaag tttgcaagta
    26281 tccgagaaat tgtcctaaaa aaccaagaac tctatatcaa ataaagcccc attgctctat
    26341 acacatccag tgtatggagc ttttttataa gcaattcaat tttatactca tctgctttca
    26401 aaaagcattc tattccatct ccgattaacg atggacttta tcacctcctt ctccagtcct
    26461 tgtatgacat cttggagttg attcatgaca tcttccaaag ttcgaaaggc tttattctta
    26521 aatccacgtt tacgaatctc tttccacact tgttcaatgg gttcatctct ggtgtgtatg
    26581 gaggaataaa ggtaaaatca atattagtcg gaatctttaa ggtacttgat ttatgccata
    26641 tagcattgtc cataacgagt aaaaaataat catctggata agcttgtgaa agctcttcta
    26701 aaaagacgtt catccactca gtattacatc caccagctat taagaaaaat gattcgcctg
    26761 tatggggcat caacagctcc ataacaatag cgaaattctc gtatatagtg actatggaca
    26821 tgtggaccta ctcctattgg agaccaacaa gatcccagtt tactgattct accgaaacca
    26881 gcctcatctt ggtacatcaa gcgaacctta tgaaaaggtc tactggtttt aaagcgcttt
    26941 cttgtcttct tgaattgaga ttttattttt agacgcgaca atggtttgag cgtctgcttt
    27001 cctaggatgt tctggacgtg gcataatatt tcgccaacca tggtgcttca acagttgata
    27061 gaaggcatca cgtgtgtagg aacgatataa gcctgaaata aggtattgta acaaattctc
    27121 ctgcctctgt agccttcaaa tggcgggcaa gaaaggcttt ctcttcctca actgtcatat
    27181 atgcatggtt acgaccacca cgtgtttctt gaaggagaga gtcgagtccg aactcctcat
    27241 atttttttac atttcgccaa atcgttgttt gattacagtc taaaagatct ataatctctt
    27301 tataagattt gcccatcaga cgaaatagaa cgatttgaag gcgtttatga tatttagctg
    27361 tacgaaagtc ttttaaaagt gttttgatgg tttggatttc ttctttagtt gatttcatat
    27421 tactattgta taatgctttt tgatttgagt ctagtattat actcttcgaa aatctcttca
    27481 aaccgcgtca gcttcgcctt gtcgtataga atgttactga cttcgtcagt tctatctaca
    27541 acctaaaaac agtgttttga gcagtctgca gctaactttc tataacaaaa tgaaataaga
    27601 acaagacaaa tcaatcaaga caatcaaatc gatttctaac aatgttttag aagtagatgt
    27661 gtactattcc agtttcaata tattatagtt tgctctttga ttttcattga gtattagttc
    27721 aatatctaaa aaaagag
//
LOCUS       DAVLBE010000024        26486 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.024, whole genome shotgun sequence.
ACCESSION   DAVLBE010000024 DAVLBE010000000
VERSION     DAVLBE010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26486)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26486)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26486
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.024"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            123..1457
                     /gene="pepC"
                     /locus_tag="VXB91_001117"
     CDS             123..1457
                     /gene="pepC"
                     /locus_tag="VXB91_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HEV0470584.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALERRQSH
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAILNKLLRQDAQILRDLLVSGADQVTVQAKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAK"
     gene            complement(1513..2424)
                     /locus_tag="VXB91_001118"
     CDS             complement(1513..2424)
                     /locus_tag="VXB91_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV0470585.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(2448..3251)
                     /locus_tag="VXB91_001119"
     CDS             complement(2448..3251)
                     /locus_tag="VXB91_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HEV0470586.1"
                     /translation="MSIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            complement(3279..4268)
                     /gene="manX"
                     /locus_tag="VXB91_001120"
     CDS             complement(3279..4268)
                     /gene="manX"
                     /locus_tag="VXB91_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HEV0470587.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQTAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
     gene            complement(4501..5520)
                     /gene="adhP"
                     /locus_tag="VXB91_001121"
     CDS             complement(4501..5520)
                     /gene="adhP"
                     /locus_tag="VXB91_001121"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HEV0470588.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKV
                     EPGQWAVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLALAKEVGADIVINGLEVE
                     DVAGLIKEKTDGGAHSAVVTAVSKVAFNQAVDSIRAGGRVVAVGLPSEMMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVVPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
     gene            complement(5872..6684)
                     /locus_tag="VXB91_001122"
     CDS             complement(5872..6684)
                     /locus_tag="VXB91_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV0470589.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKKTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASD
                     KYALAKEMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            6874..8292
                     /locus_tag="VXB91_001123"
     CDS             6874..8292
                     /locus_tag="VXB91_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HEV0470590.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLVITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     DVHAMIWILDALFILNYISMAL"
     gene            8345..9052
                     /locus_tag="VXB91_001124"
     CDS             8345..9052
                     /locus_tag="VXB91_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0470591.1"
                     /translation="MKEKNMWKELLNRAGWILVFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLIVTGLSIVVLALFIMGARKTKLASFNFSFFRAKDLARLGLSYLVIVGSNILGS
                     ILLQLSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGIVPKKIFRGKE
                     NLGFVVGTIVFALLHQPSNLPSLLIYGGMSTVLSWTAYKTQRLEMSILLHMIVNGIAF
                     CLLALVVIMSRTLGISV"
     gene            9147..10121
                     /gene="folP"
                     /locus_tag="VXB91_001125"
     CDS             9147..10121
                     /gene="folP"
                     /locus_tag="VXB91_001125"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HEV0470592.1"
                     /translation="MMKILEGVTDMSSKANHAKTVICGIINVTPDSFSDGGQFFALEQ
                     ALQQARKLIAEGASMLDIGGESTRPGSSYVEIEEEIQRVVPVIKAIRKESDVLISIDT
                     WKSQVAEAALATGADLVNDITGLMGDEKMAHVVAKAGAKVVIMFNPVMARPQHPSSLI
                     FPHFGFGQTFTEKELADFETLPIEDLMVAFFERALARAAEAGIAPENILLDPGIGFGL
                     TKKENLLLLRDLDKLHQKGYPIFLGVSRKRFVINILEESGFEVNPETELGFRNRDTAS
                     AHVTSIAARQGVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK"
     gene            10123..11445
                     /locus_tag="VXB91_001126"
     CDS             10123..11445
                     /locus_tag="VXB91_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEV0470593.1"
                     /translation="MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVLHI
                     GGTNGKGSTIAFLKKMLEKLGLRVGVFSSPYLIHYTDQISINGESISEARLEALMADY
                     QSLLEGEAVANLQGTTEFEIITALAYDYFASEQVDVAIMEVGMGGLLDSTNVCQPILT
                     GITTIGLDHVALLGDTLEAIAEQKAGIIKQGMPLVTGRIAPEALTVIDRIAEGKDAPR
                     LAYGTDYQVRHQESVVTGEVFDYTSAVRQGRFQTSLLGLYQIENAGMAIALLDTFCQE
                     DGRELASNDFLGQALEETSWPGRLEIVSRDPLMILDGAHNPHAIKALLVTLQERFADY
                     HKEILFTCIKTKALGDMLDLLGAMPDTELTLTHFADSRATDESVLKEAAKSRNLSYQD
                     WHDFLEQNLTDKKEEKQTVRIVTGSLYFLSQVRAYLMERKNENGYTKD"
     gene            11426..11980
                     /gene="folE"
                     /locus_tag="VXB91_001127"
     CDS             11426..11980
                     /gene="folE"
                     /locus_tag="VXB91_001127"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HEV0470594.1"
                     /translation="MDTQKIEAAVKMIIEAVGENANREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVVIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            12023..12835
                     /gene="folK"
                     /locus_tag="VXB91_001128"
     CDS             12023..12835
                     /gene="folK"
                     /locus_tag="VXB91_001128"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HEV0470595.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFESYPLVQEMKLELKKPWA
                     PVHLSLDTCSVTIHRRKQRAFIALGSNMGDKQANLKQAIDKLRARGIYILKESSVLAT
                     EPWGGVEQDSFANQVVEVETWLPAQDLLETLLAIESELGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPILKQPIRNLYDALKK"
     gene            complement(12880..13197)
                     /locus_tag="VXB91_001129"
     CDS             complement(12880..13197)
                     /locus_tag="VXB91_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HEV0470596.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMDGRETILLPEEN
                     DLF"
     gene            13554..14000
                     /gene="rplM"
                     /locus_tag="VXB91_001130"
     CDS             13554..14000
                     /gene="rplM"
                     /locus_tag="VXB91_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HEV0470597.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISGLI"
     gene            14019..14411
                     /gene="rpsI"
                     /locus_tag="VXB91_001131"
     CDS             14019..14411
                     /gene="rpsI"
                     /locus_tag="VXB91_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HEV0470598.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
     gene            complement(14673..15095)
                     /locus_tag="VXB91_001132"
     CDS             complement(14673..15095)
                     /locus_tag="VXB91_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEV0470599.1"
                     /translation="MRFIVETFPIFSISNDLLQLLTSWKKQQKYELAKFGIISNPEQF
                     IFTYIDTKGNINKPLHSDYLNNKMKTIRKRHPELTHATPHKLRHTGATLAKQAGMSLE
                     AISEALIHSDTGTTQIYVNTSNVVPMAVGEFALQSLKQ"
     gene            15242..15418
                     /locus_tag="VXB91_001133"
     CDS             15242..15418
                     /locus_tag="VXB91_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0470600.1"
                     /translation="MSLDIDKEKMTIMGIAFENRSVFKSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALALGMT"
     gene            15820..18033
                     /locus_tag="VXB91_001134"
     CDS             15820..18033
                     /locus_tag="VXB91_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 31 protein"
                     /protein_id="HEV0470601.1"
                     /translation="MKIFKGEFYRISVLTDKLVRLEYSRTGNFEDRTTQLIYNRDFGQ
                     VSLDYIETSNVLDIMTDYFHLHFNKGEFNAENLFIELKGNFAVYGSRWYFGESIETLK
                     GTARTLDKADGAISLEDGIISRNGIALLDDSQGFIWDEQSGYIERENQIDLYFFAYGH
                     DYRGAIRDFYHLTGSTPLLPRYALGNWWSRYWPYTSDEYLDLIDRFETEKIPLSIGVL
                     DMDWHITDIPARFGSGWTGYSWNRNLIPNPEQLLQQLHDRKLKLSLNVHPADGIRAYE
                     EAYPQIAKRLGLNVELEEPAIFDFFNPSFREAYFKDVHYELEKQGVDFWWIDWQQGTQ
                     GMLDPLWLLNHYHYQDSCKNAEGGLILSRYAGPGSHRYPVGFSGDTIISWNSLRFQPY
                     FTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHSSRSPFNSKEPW
                     FFSETTSKIMKKYLRLRHQMIPYLYTMNVKTHEEGAPLISPIYYFYPENDESYNVPNQ
                     YFFGTELMVAPIVEKMDLTFQSAKVDVWFPEGEWYDFFSEKKYTGGVKLSVYRDISTT
                     PVFAKSGAIIPLVGSEIGMGVDLPEVVDWYVFPGKQHSFEMLEDQNGQRYKTRLSIDW
                     EMGMVELALQGDSSIVPSNRKHRIHFKGTNVSIIELPNKNDTAKFEWKDNKRTSLNDE
                     VFRLLKTASLPYELKDRLLNQFINAKNSHDLMNILHHQDKELRGRLLEMIFTSQN"
     gene            complement(18255..18731)
                     /locus_tag="VXB91_001135"
     CDS             complement(18255..18731)
                     /locus_tag="VXB91_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HEV0470602.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQG
                     LQELYERYQAQGFEILDFPCNQFMGQAPGSAEEINAFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLKDQKSGPLGKRIEWNFSKFLIGRDGQVFERFSSKTDPKQIEEAIQTLL"
     gene            18954..22157
                     /locus_tag="VXB91_001136"
     CDS             18954..22157
                     /locus_tag="VXB91_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
                     /protein_id="HEV0470603.1"
                     /translation="MQTKTKKLIVSLSSLVLSGFLLNHYMTVGAEETTTNTIQQSQKE
                     VQYQQRDTKNLVENGDFGQTEDGSSPWTGSKAQGWSAWVDQKNSSADASTRVIEAKGG
                     AITISSHEKLRAAVHRMVPIEAKKKYKLRFKIKTDHKVGIAKVRIIEESGKDKRLWNS
                     ATTSGTKDWQTIEADYSPTLDVDKIKLELFYETGTGTVSFKDIELVEVADQLSEDSQT
                     DKQLEEKIDLPIGKKHVFSLADYTYKVENPDVASVKNGILEPLKEGTTNVIVSKDGKE
                     VKKIPLKILASVKDAYTARLDDWNGIIAGNQYYDSKNEQMAKLNQELEGKVADSLSSI
                     SSQADRTYLWEKFSNYKMSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSME
                     WMHKHVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDP
                     EHFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGF
                     YQDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKNPIDKDKMQTMYYWIDKSFAP
                     LLVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQ
                     SDSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRTSYLSAFNKMDKTAMYNAEKGFGF
                     GLSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTE
                     TDAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFL
                     GSNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDS
                     KKNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNGDSYGYM
                     LIPNVGRATFNQMIKELESSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVL
                     KRGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKLEQAAQPQVQNSKEKEKSEEEKN
                     HSDQKNLPQTGEGQSILASLGFLLLGAFYLFRRGKNN"
     gene            22537..22922
                     /gene="tnpA"
                     /locus_tag="VXB91_001137"
                     /pseudo
     CDS             22537..22922
                     /gene="tnpA"
                     /locus_tag="VXB91_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005816675.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(23301..23930)
                     /locus_tag="VXB91_001138"
     CDS             complement(23301..23930)
                     /locus_tag="VXB91_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEV0470604.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSTLSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYVTLR"
     gene            complement(23940..24941)
                     /locus_tag="VXB91_001139"
     CDS             complement(23940..24941)
                     /locus_tag="VXB91_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEV0470605.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITVAIGQEVRAILLLLLEEAKRRGI
                     VVSMDLNLRTKMISVLEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKEAYGFKAIFHTLRSSDEQDKNVYQAYALEERFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSATSIENLLANAQDIIR"
     gene            complement(24972..25613)
                     /locus_tag="VXB91_001140"
     CDS             complement(24972..25613)
                     /locus_tag="VXB91_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HEV0470606.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKDYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLAK"
     gene            complement(25632..26447)
                     /locus_tag="VXB91_001141"
     CDS             complement(25632..26447)
                     /locus_tag="VXB91_001141"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HEV0470607.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIEAYREVGIEAHGYVCDVTDEDGIQAMVKQIEQEVGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
BASE COUNT         7971 a         4946 c         5799 g         7770 t
ORIGIN      
        1 agagattttc gaagagtata aattcgaaaa aggtgaggga gaatgtcctt accttttatg
       61 ttttttagtt gcttcctttg tgaaaagagt tataatagac tgtagaataa aaggaggaat
      121 ctatgaacgc gattcaagaa tcatttactg ataaactatt tgccaactat gaagcaaatg
      181 taaaatacca agcgattgaa aatgctgcca gccacaacgg aatttttgca gctctggaac
      241 gtcgccaaag ccatgtagac aacacacctg ttttctcatt ggatttaacc aaggacaagg
      301 tcactaacca gaaagcgtct ggtcgttgct ggatgtttgc ggctctcaac accttccgcc
      361 acaaactcat ctcgcaatac aaattggaga actttgagtt gtcacaagcc cacactttct
      421 tctgggataa gtatgagaaa tcaaactggt tcttggagca agtcattgcg acttcagacc
      481 aagaattgac tagccgcaag gttagcttct tactccaaac acctcaacaa gatggtggtc
      541 aatgggatat ggtcgtttcc ctctttgaaa aatacggtgt cgtgcctaag tcagtttatc
      601 ctgagtctgt ttcatctagc agcagtcgtg agctaaatgc gatccttaat aaattgcttc
      661 gtcaagatgc tcaaatcttg cgtgatttgc ttgtttctgg tgcagatcaa gtgactgttc
      721 aagctaagaa agaagacctc ttgcaagaaa tctttaactt tcttgctatg tcattaggac
      781 ttccaccacg caagtttgac tttgcttatc gcgataaaga taacaactac aaaagtgaaa
      841 aaggaatcac accacaagag ttctacaaga aatatgtcaa tcttccttta gaagactacg
      901 tttctgttat caatgctcca actgctgata aaccttacgg aaaatcttac acagttgaga
      961 tgttggggaa tgtggttggt agccgtgcag ttcgttacat caacgttcca atggagcgct
     1021 tgaaagaatt ggcgattgcc caaatgcaag caggtgagac tgtttggttt ggttctgatg
     1081 tcggccagct cagtaaccgt aaggctggaa tccttgcgac agatgtttat gactttgaat
     1141 caagcatgga cattaaactt actcaagaca aggctggacg tttggactat agcgaaagct
     1201 tgatgaccca cgccatggtc ttgacaggtg ttgacttgga cgaaaatggt aaatcaacca
     1261 agtggaaggt tgaaaactca tggggagaca aggtcggtac agatggttac tttgttgcct
     1321 cagacgcttg gatggacgaa tacacatacc aaatcgttgt tcgtaaggaa ttgctgacag
     1381 cagaagaaca agctgcctat ggagcagaac caattgtact tgcaccatgg gatccaatgg
     1441 gagccttggc taaataaaag catagaaaaa aggaatcaga ttttagaacc tggttccttt
     1501 ttagttgctt gattacatga tgtgaagaac atgtgccaca atacccactg cgaagagggc
     1561 aaggataata gtgattggag atactttttt cttaagtaag tacatgcaaa gtaaagtaag
     1621 gagtagtcct gataatccag gaatcaacat atccaagttt tgttggaaag tagtaacttt
     1681 ttcaggagtt tgagacaatc cttgtcctac ttgtgcgaat gcttcttgga tacctttaga
     1741 cccttctggc aatttatccc aatggatata agccttttca tctagttgaa ctttagaaac
     1801 atcgaaagca aatttaatat ttacccagcg ttgaacaagg acagcaagaa tgaacatccc
     1861 aaggatagaa gctcctttag tgatatcttg aaggatacca ccagacatat ctttagtgat
     1921 ttctgatcca gccttgtatc caatctcttg aacataccac aagaatgaca tacgaatcaa
     1981 gttccatgca acaaagaaga ggagtggccc caagatattg ccagtaaggg caagtgaagc
     2041 accgagagat ccaaggattg ggcgtactgt aaaccagaat actgggtcac cgataccagc
     2101 aagaggtccc atcataccga ttttaacccc ttggatagca gcgtcatcga tttccacacc
     2161 gttagcacgt tcttcttcaa gcgcaagagt aacccccatg actggagcag ctacgtatgg
     2221 atgagtgttg aagaactcaa ggtgacgctc aagagcagcg atttgatctt cttttttagt
     2281 atagagtttt ttgatagctg gaatgagtgt ataagcccag cccaagtttt gcatccgttc
     2341 aaagttccaa gacccttgta agaaggttga acgccaccaa acttttttac gatctgattt
     2401 agttaattga agtttttcag tcatgatgtt ttcagtcctt tcttatctta gtagtcttct
     2461 aggatatcgc cgattgggtc gttagaagtt gcggctcctc cgccaccatt tccaccagtt
     2521 ttagaaaggt gaaggtagat aagagcgata gcaacaccga tagcaccgaa tccgattaga
     2581 gtaatatctg acacagcagc gagaacgaaa ccaagagcga agaatggcca tacttcacga
     2641 gttgccatca tgttgataac catggcgtaa ccaacggcaa cgaccatacc accaccgata
     2701 gccataccat ctttgagcca gtctggcatg gcactaagga tactttgtac agtttcagtt
     2761 ggtaccataa ggagaagagc tgcaggaagc gcgatacgaa gtccttggaa gagtagcgca
     2821 atgaaatgcg cacgctccac agcgccgaag tcaccttttt tagcggcagc atctgcagta
     2881 tgaaccaaac caactgaaat tgtacgaaca atcattgtca agaaaagtcc agctacggca
     2941 agagggatag caaccgcttg ggcaacaccg ataccagtct tggtaaagtc accaccaaga
     3001 accatgataa tggcagcagc gacagaagca agtgcagcat caggagcgat agcagcaccg
     3061 atatttgacc aaccaagggc aatcatttga agcgatccac cgaggataat ccctgcttcc
     3121 aagtgacctg ttacaagccc aataagggta caggctacaa gtggttggtg aaattggaac
     3181 tggtcgagga tgccttcaag acctgcaaag aaggctacaa cgactactaa aaccatagaa
     3241 ataatagaca tgtttaaaat cctttcataa ataatggctt atttgacatt ggctttgtta
     3301 atcaagtcaa acaaatcttt tttagaatca tttggtactt tacggacatc aaattcaaca
     3361 cccaagtcac gcattttttc aaatgtagca acatcttctt tgtccataga caaaacggta
     3421 ttgaccaatg ttttacctgt tgagtgagcc atagaaccaa cgttaagagt cttgattggc
     3481 acgccgcctt cgatggcacg aagggcatct tgaggtgttt caaacaagat aagggcatgt
     3541 gtttctccaa aacgtgggtc ttttgaaatc tcaatcagtt tttgaattgg aaccacgtta
     3601 gccttgacat tacctggagc tgcttgttta atcaattctt tacgaaggtc gtctttagcc
     3661 acgttatctg aagcaacgat gatacgattt gcttttgaat ctggagtcca agcagttgca
     3721 acctgaccgt gaagtagacg tgtgtcaaga cgggcaagat tgattttcaa tttaccgtct
     3781 ccgataacag ttccttctgg gatagcagtt tgggcaactg gagcagctgc agcgcttgca
     3841 acttcttcaa ctggatttag ctcttctgga agagctttga tgccatcttt ggcttcttta
     3901 atgatattag cagcgacttt ttctacacct gcagcagcgt ccatgaggcg ctctgtgtag
     3961 gcttgaatca acatcggtaa gttaagtcct gtgatgatgg caaacttacg ctcaggattt
     4021 tctcccatca cgcgactagc ttggttaaat ggagaaccac tccaaaggtc agccaaaact
     4081 agaacctcat cttctgcgtc aaatgcagca acagcgttat taaacttagc gtatagatca
     4141 tcaggacctt catttggcat aaaggtcaca acttgaacct tttcttgttc accaaagatc
     4201 atagatcctg actgatgaat acccgcagca aattcgccgt ggctcgcaat aatgattccg
     4261 atactcatta ttgtcattcc tccttttttg ttttagtttt catttaggaa aactttaaga
     4321 ctgtttaagt ataaaccgtt ttcataaaaa aagcaactat ttatcataaa aaattaaaaa
     4381 atttttattt ttgtatgttg atatgttgag tttttgagga gtaatcttga attcttattt
     4441 aaaatttaat ataaaaaagt tggaagaagc ttccaacttt taaaataggt ttctattaga
     4501 ttagtgggtg aagtcgagta ccatacgtcc ttggatttgg cctttttcca tttcgtcgaa
     4561 aatggcaaca gcatcttcta ctggacgttt ttgaacaact gggactacca gaccttctgc
     4621 accaaattgg aaggcttctt ctaagtcttt acgagttccg acaagagaac cgatgacttg
     4681 gattccatcg aggactgttt taacgatgct gagttccatc atttcagaag gaagaccaac
     4741 agcgacgacg cgaccaccag cacgaatgga gtcaacagcc tggttgaagg caactttaga
     4801 cacagcagtt acgacagctg aatgagctcc tccatcagtt ttttctttaa tgagtccagc
     4861 tacatcttca acttcgaggc cgttaatcac aatgtcagcg cctacttctt ttgcaagggc
     4921 aagtttgtca ttgttgatat cgactgcgat aacatgagca ttgaatactt ttttagcgta
     4981 ttgaacagcg aggttaccaa gtccaccagc accgtaaaga acagcccatt ggcctggttc
     5041 aacttttgct tctttgatag ctttataggt tgttactcca gcacatgtga tagaagaagc
     5101 ttgggctgga tcaagtccgt caggaacttt gacagcatag tcagcagtta cgatacattg
     5161 ttcagccata ccaccgtcta ctgagtagcc agcatttttc actgtacggc aaagggtttc
     5221 gcgaccagtt gtacagtatt cgcaagtgcc acatccttca aagaaccaag caacgctgac
     5281 gcggtcaccg actttaaggc ttttcacatc tggagcaatc tctttaacga taccgatacc
     5341 ttcgtgccca agaacacgtc ctgggacttg accaaagtca ccatgagcaa cgtggaggtc
     5401 ggtgtggcaa acgccacagt attcaacttc tacaagtgct tccccagttt caagtggacg
     5461 gagtactttt tcttcaatag caacaccagt gctttctgga tttacaacaa cagctttcat
     5521 agctatcctc cttgatattg accgagaaca gggacaacgg gactggattg attttttgtc
     5581 aacagagtcg agtgtgacga gctctcttgt atttatatgt gaagtatatc acaaaagaaa
     5641 gccttttcca aggttttgga gacaaaaagt agaacaatcg attaactggt tgatgagact
     5701 gtgaaaagag cacaaagacc agcttgcaag ctggtcatac tcttcgaaaa tctcttcaaa
     5761 ccacgtcagc ttcatctaca acctcaaagc agtgctttga gcaacctacg gctagcttcc
     5821 tagtttgctc tttgattctc attgagtatc agtataggtt ataagaataa gttataagaa
     5881 taagtcttgt agggttttgg caaccccatc ttggtcgttg gtaagggaaa tttgctcatc
     5941 tgcataaggg agtagctctg gattggcatt tttcatggca taacccttcc cagcaaaagc
     6001 gagcatttcg gtatcattgt gttcatctcc aaaggcaatc aaatcttttt tgtcacgatt
     6061 cattatcttg agcaagtagt ccaaagcaaa ggccttgttg acaccttttg gggtacattc
     6121 aaggatattg agcggacctc cccaggtatt gatagaaagt tgatgctggt agaaggcgtt
     6181 catttctttt gccaaggcat atttgtcact ggctctggtc tgcaagagga tacagttagg
     6241 gtccttggtc accaattcag gctggaattg atcttcaggc tggaaagctt ctacaccaaa
     6301 tagtttggga ttggcaattt cttcattggg atttgtaatg tagaattttt tacgatattc
     6361 tccagcgata aaatcggctt gaatgtcctc tgaacgttga accatatcta gcagatattt
     6421 tttgtctaca gtcaaacact tttcaaaatc ccaaacttgg tctggtaaat gagtaaggga
     6481 tccgttgaag ttaatcatag gagtgtctaa gcccagttca cggtaaaaat cttttgacat
     6541 acggtaaggg cgacctgtcg taataataac ctgatggcct ttttcagcaa cttttttgat
     6601 ggtttttttg gtaaagtcag aaatttgact gtctgagttg agcagggttc catctaggtc
     6661 aactgcaata atttttttcg tcatatggac ctttctagtg tgttttcaga taagatgtct
     6721 tctattataa cagaaagcag gcagaaaagc agattccaaa caaaaaatga aattggatta
     6781 atttcttaaa caaatcaaac aaagacattg aaaaagtgaa tgataaatga tataattcta
     6841 ttattgttcg taaaaattaa aaggagattg atgatggaca aattatttaa actaaaagag
     6901 aacggtacag acgttcgtac agaggttctc gctggtttaa caactttctt tgcaatgagc
     6961 tatattctct ttgtaaaccc acaaattctt tcgcaaacag gaatgcctgc tcagggtgtg
     7021 tttcttgcaa cgattatcgg tgcagttgct ggtaccttga tgatggcctt ctatgctaac
     7081 ttgccatacg ctcaagcacc aggtatggga ctcaatgcct tctttacctt tacagtcgta
     7141 tttggacttg gttattcatg gcaagaagcc ctagctatgg tcttcatctg tgggattatt
     7201 tcattggtta ttaccttgac aaatgttcgt aaaatgatca ttgaatcgat tccaaatgcc
     7261 cttcgctcgg ctatttcagc tggtatcggt gtcttccttg cctatgtagg gattaagaat
     7321 gctggacttt tgaaatttac gattgatcca ggcaactata ctgttgtagg agaaggggct
     7381 gacaaagctc aagcaacgat tgcagcaaac tcttcagcag ttccaggctt ggtcagcttt
     7441 aataatccag ctgttttagt ggctcttgca ggacttgcca ttactatctt ctttgtcatc
     7501 aaagggatta aagggggaat tattctctct atcttgacaa caactgttct tgctattgca
     7561 gttggtttgg ttgatttgtc tagtatcgat tttgctaata accatgttgg tgcagctttt
     7621 gaagatttga agacaatctt tggtgcagct cttggttcag aaggtttggg agctttggtt
     7681 tcagatacag ctcgcttgcc tgaaactctg atggccattc ttgccttctc attgacagat
     7741 atttttgaca caattggtac cttgatcggt acaggtgaaa aagttggtat tgtagcgaca
     7801 aatggtgaaa atcaccaatc agccaaattg gataaggctc tttactctga tttgattgga
     7861 acgacagtcg gtgccattgc aggtacttca aacgtaacga cttatgttga gtctgctgct
     7921 ggtatcggtg caggtggacg tactggtttg acagccttgg ttgtagctat ctgttttgcg
     7981 atttcaagct tctttagccc acttctagcg atcgtaccaa cagcggctac agctccaatc
     8041 ttgattatcg ttgggattat gatgcttggt agcttgaaaa atatccattg ggatgatatg
     8101 tctgaagcag ttcctgcctt cttcacatct atctttatgg gattcagcta ctctatcact
     8161 caagggattg cagttggttt cttgacttac actttgacta agcttgtcaa aggtcaagtt
     8221 aaagatgttc atgccatgat ttggattttg gatgccttgt ttatccttaa ctacatcagc
     8281 atggccttat aatagaatga cccaggggga tttcccccct tttttaatac aaaggagata
     8341 ggtgatgaaa gagaaaaata tgtggaaaga attgttgaat cgtgcaggct ggattttggt
     8401 ctttttactt gccgtccttt tatatcaggt tcccctagtg gttacctcta ttttgacttt
     8461 aaaagaagta gccctgctac agtcagggct gatagttact ggcctttcaa ttgtggttct
     8521 ggctctattt attatgggag ctcgtaaaac caagttagct agttttaatt tttctttttt
     8581 tagagctaaa gatttggcac gtttgggctt gagttattta gttattgtcg ggtcaaatat
     8641 acttggttct atcttgttgc aactgtcaaa tgagacgaca acagctaacc agtctcagat
     8701 taacgatatg gttcagaata gttctctgat ttctagcttc ttcttgctag ccttgcttgc
     8761 tccaatttgt gaggaaatct tgtgccgtgg gattgttcct aaaaagattt tccgaggcaa
     8821 ggagaacttg ggatttgtag tcggtacgat tgtgtttgct ttattgcatc aaccaagtaa
     8881 tttaccttct ttattgattt atggaggtat gtcgacagtt ctatcttgga cggcctacaa
     8941 gacccaacgt ttggaaatgt cgatcttgct tcacatgatt gttaatggga ttgctttctg
     9001 tttgttggct cttgtggtga ttatgagtcg gacattagga atttctgttt aaaagttttt
     9061 atgtaggaac cgacctcttt ctactaggga aagatgaatg caatcgtgtc catctttttc
     9121 tttttatggt aaaatagaaa aataatatga tgaaaatcct tgagggagtg accgatatgt
     9181 caagtaaagc caatcatgca aagacagtta tttgcggaat tatcaatgta accccagact
     9241 ccttttcgga cggtggtcaa ttttttgctc ttgagcaggc actccagcag gctcgtaaat
     9301 tgatagcaga aggagccagt atgctcgata tcggcggaga atcgactcgg ccgggaagta
     9361 gctatgttga gatagaagag gaaatccagc gtgttgttcc agtgatcaaa gcgattcgca
     9421 aggaaagtga tgtcctcatc tctattgata cttggaagag tcaagtagca gaggctgctt
     9481 tggctactgg tgccgatcta gtcaatgata tcactggtct catgggtgat gaaaaaatgg
     9541 cccatgtggt tgctaaagct ggagcgaaag tggtcatcat gtttaaccca gttatggctc
     9601 gacctcagca tcctagttcg cttatcttcc ctcattttgg ctttggtcaa acctttacag
     9661 aaaaagagtt agctgacttt gaaacattgc caatcgaaga cttgatggtg gctttctttg
     9721 aacgagcact agcgagagcg gcagaagctg gtattgcacc agaaaatatc ctgttggatc
     9781 caggaattgg ctttggtctg accaagaaag aaaatcttct ccttttacgg gacctggata
     9841 aactacatca gaagggctat ccaatctttc tcggagtgtc gcgcaagcga tttgtcatca
     9901 atatccttga agaaagtggg tttgaagtca atcctgagac agagcttggt ttccgaaatc
     9961 gggacacggc ttcggctcat gtaactagta tcgctgcgag acagggtgta gaagtggtgc
    10021 gcgtgcatga cgtagctagt cacaggatgg cagttgaaat tgcctctgcc attcgtctgg
    10081 ctgatgaagc ggaaaattta gatttaaaac aatataaata agatgaaaga aattgaaaac
    10141 aatcagtgga ttgctaacta ccggacggat caaccgcatt ttggcttgga acgaatggtg
    10201 gaactgttag ctttgcgtgg caatccccat cttaaactca aggttctcca tatcggaggg
    10261 actaacggca agggctcgac tattgctttt ttgaaaaaga tgctagaaaa gctagggctg
    10321 agagttggcg tgtttagttc gccctatctc attcattaca cagaccagat tagcatcaat
    10381 ggggaatcga tctcagaagc gaggctagaa gctctcatgg cagactatca gtctttgctg
    10441 gagggagaag cggtcgccaa tttacagggc acaaccgagt ttgagattat cacagcccta
    10501 gcctatgact actttgcctc agagcaagta gatgtggcta tcatggaagt tggcatgggt
    10561 ggacttttgg atagtaccaa tgtctgtcag cccattttga caggaattac aactattggc
    10621 ttggatcatg tggccctact tggtgacacc ttggaggcca tagcagagca gaaggcaggt
    10681 attatcaaac aagggatgcc cttggtaaca gggcgtattg ctccagaagc cttgactgtg
    10741 attgaccgca ttgcggaagg gaaagatgcg ccgagacttg cctacgggac agattatcag
    10801 gttcgtcatc aagaaagtgt ggtgacaggg gaagtctttg actatacaag tgctgtcaga
    10861 caaggtcgct tccagactag cctgcttggt ttgtaccaaa tagagaatgc tgggatggcc
    10921 atagctttac ttgatacttt ttgtcaagaa gatggtcgag agctagcaag caatgacttt
    10981 cttggtcaag ccttggaaga aacaagttgg ccagggcgtt tggaaatcgt gtcaagagat
    11041 cccttgatga ttttggatgg agcccataat ccccatgcta tcaaggcctt gttggtaacc
    11101 ttgcaagaac gttttgcgga ttatcataag gaaatcctct tcacttgtat caaaaccaaa
    11161 gccttggggg atatgttgga cttgctggga gccatgccag ataccgagct tactctaaca
    11221 cattttgcgg atagtcgggc gacggatgaa agcgtgctga aagaggcagc taagtctaga
    11281 aatctcagct accaagattg gcatgatttt ctagagcaga atttgacaga taaaaaagaa
    11341 gagaaacaaa cagttaggat tgtcacaggt tccttgtatt tcttgagcca agtgagggcc
    11401 tatctgatgg agaggaagaa cgagaatgga tacacaaaag attgaagcag ctgtaaaaat
    11461 gattatcgag gctgtaggag agaacgctaa tcgcgagggc ttgcaggaaa cacctgctcg
    11521 tgtagcccgt atgtatcaag agattttttc aggtcttggt caaacagcag aggaacattt
    11581 gtcaaaatcc tttgaaatta ttgacgataa tatggtggta gaaaaggata tctttttcca
    11641 taccatgtgt gaacaccact tcttgccatt ttatggtaga gcgcacattg cctacattcc
    11701 agatggtcgt gtggcaggct tgtctaagct agcccgtacg gttgaagttt attcgaaaaa
    11761 accacaaatt caagaacgtt tgaatatcga agtggccgat gccttgatgg actatctagg
    11821 tgctaaagga gcctttgttg tcattgaggc ggaacatatg tgtatgagta tgcgtggtgt
    11881 tagaaaacca ggcactgcaa ccttgacgac agtagctcgt ggtctatttg aaacagataa
    11941 ggacctccgc gaccaagctt atcgtttaat ggggctataa aaagaatccg tttcaagcgg
    12001 atttttctag aaaggaatca ttatggatca actgcagatt aaggatttgg aaatgtttgc
    12061 ctatcatggt ctttttccta gtgagaaaga attggggcag aaatttgtcg tttcagccat
    12121 cctatcctat gatatgacca aggcagctac agacttggat ttaacagcct ctgtccatta
    12181 cggagaattg tgtcagcagt ggacgacttg gtttcaggaa acgagtgaag atttgattga
    12241 aacggtagcc tataaactgg tggaacgtac ctttgagtct tatcctcttg tccaagaaat
    12301 gaagttggaa ctgaaaaaac cttgggcacc ggtgcatttg tcactagata cttgctcggt
    12361 aaccattcat cgccgcaagc aacgagcctt tatcgcccta ggaagcaata tgggagataa
    12421 acaagcaaac ttgaagcaag ccattgacaa actgcgagct cgtggcatct atattctcaa
    12481 agagtccagt gtcttagcga cggagccttg gggtggagtg gagcaggata gctttgccaa
    12541 tcaagtggtt gaggtggaaa cctggctacc agcacaagac ttgttagaaa ccttgttagc
    12601 cattgagtca gagctgggac gggtgagaga agtgcattgg ggacctcgtt tgattgattt
    12661 ggacttgctc tttgtggagg accagatcct ttatacagac gacctcatat tgcctcatcc
    12721 ttacatagcg gaacgccttt ttgtccttga gtccttacag gaaattgcgc ctcattttat
    12781 ccatccgata ttaaaacaac cgatccgtaa cttgtatgat gctttgaaaa aatagaaaaa
    12841 ctctagtttt cagttacttg caactgaagg ctagagtttt taaaataggt cattttcttc
    12901 tgggaggagg atagtttctc taccgtccat gtctaaaacc agtactcttg ggggataacg
    12961 agggtcgaaa ggatggttaa agtcaaaatc aatggctgta gggaggtgtt gacttgaaaa
    13021 gtggaaggta atctttcctt ggttattaag caattgaaac tcgagttctt cttccaattc
    13081 aaagacattt tttaagaaat ggtcgataat ataccaaaaa gagtcaatga tgtcatcagg
    13141 caagctggta acaatgccaa aactagcaga ccgcatgtgg gtattggtaa aagccatatc
    13201 tctgtctcct ttcttttccc ttatcataca gcaaatagga ttaaaaatca agaaaaggtg
    13261 attttttgaa aaggatttta actacaggga aaaagaagga aaaaaattcc caaaaatcta
    13321 ccgaagttaa taggtaaatt cccaaattaa cttgattata taactttcag ttattttgag
    13381 aagttaccga aaaatatttt ttatatctat tgacttttag gggtgaaatt tggtatgata
    13441 gtaggcggta ttgtttaccc catttgaaag gccccggaac cttccaaata cttttcgatg
    13501 ggaaggaaca cccatcaccg taaacaaaaa tcgaactata tataggagaa atcatgaaca
    13561 aaacaacatt tatggctaaa ccaggccaag ttgaacgtaa atggtacgta gttgacgcaa
    13621 ctgatgtacc acttggacgt ctttctgcag tagttgctag cgtacttcgc ggaaaaaaca
    13681 aaccaacatt tacaccacac actgatacag gtgacttcgt gattgttatc aatgctgaaa
    13741 aagttaaatt gactggtaaa aaagcaactg ataaaatcta ctacactcac tcaaaccacc
    13801 caggtggatt gaaacaaatc tctgcaggtg aacttcgttc taaaaatgca gtacgtttga
    13861 ttgagaaatc agttaaaggt atgcttccac acaatacact tggacgcgct caaggtatga
    13921 agttgaaagt atttgttgga gctgagcaca ctcacgctgc acaacaacca gaagttcttg
    13981 acatttcagg acttatctaa ggaaaggaac aataaagtat gtcacaagca caatatgcag
    14041 gtactggacg tcgtaaaaac gctgttgcac gcgttcgcct tgttccagga actggtaaaa
    14101 tcactgttaa caaaaaagat gttgaagagt acatcccaca cgctgacctt cgtcttgtca
    14161 tcaaccaacc attcgcagtt acttcaactg taggttcata cgacgttttc gttaacgttg
    14221 taggtggtgg atacgctggt caatcaggag ctatccgtca cggtatcgct cgtgcccttc
    14281 ttcaagtaga cccagacttc cgcgattcat tgaaacgcgc aggacttctt acacgtgact
    14341 cacgtaaagt tgaacgtaag aaaccaggtc ttaagaaagc tcgtaaagca tcacaattta
    14401 gtaaacgtta attcgaaaga attactatac ttatacagag cacctttcgg ggtgttcttt
    14461 ttttatactt tcttactaaa ttggtgcaat tgacacagtt gttgcgactt tagtcgctta
    14521 caaatgtggc tgcaacctga caaggtcagt tgcctcaaaa cgttaatcaa tacaattata
    14581 tcaacgtttc aaagcactca agagtttacc tcatgggtgc tttttttatg ttttttgaaa
    14641 aagttcacct caaagtttac cttattttca ccttattgtt ttagagactg taaggcaaat
    14701 tcaccgacgg ccatagggac tacattagaa gtattgacat aaatctgtgt tgtacctgtg
    14761 tcgctatgta ttagagcttc agaaatggct tctaagctca ttcctgcttg tttagcgagc
    14821 gttgctccgg tatgacgtag tttgtgtggc gtagcgtgtg taagctctgg gtgtcgtttt
    14881 ctgatagttt tcatcttatt attgagatag tcagaatgta aaggtttatt gatattgcct
    14941 ttggtatcta tgtaagtaaa gatgaattgt tctggattac tgatgatacc aaactttgcc
    15001 agttcatatt tttgttgttt tttccatgaa gtcagaagtt gaagtaagtc attagaaata
    15061 gagaaaatgg gaaatgtttc cacaataaaa cgcatattat cagatggtta atgcgtttta
    15121 tatttgggtt tgaggcttat aaaataggat aagcgtactg aaaacttaga tatgacaaac
    15181 aaaataaaat ttttaaaagc tacatagaaa catggtataa tgtatctaaa ggaggtagca
    15241 tatgtcctta gatatagata aagaaaagat gacaatcatg ggaatagctt ttgaaaaccg
    15301 atccgttttt aagagtgttt ggtatgcttt aagtacaaat atgattgaag gatggcgacc
    15361 tacggttagt gatgttgaaa aattacgaga tgaagctctt gctctgggga tgacttaatg
    15421 aagcgcaact gttatgaatc ttatgactat gttgatccgg ataatttata taccgatccg
    15481 ggttcttcag ttctaagaaa taagcaggaa ggaaaaaagc acgcgagctt gaatatcgta
    15541 tgattgctag taagagtttg aaattattta tcaatcctat cttagttaat agtttaaaag
    15601 tagtttgttt cacaactgca taagcttaga aaagttgaaa agtgataact ctttaataaa
    15661 ctcttggttt gttaaaagat attttgtcca ctacattttt ttcaattgac tattatttgt
    15721 catagatata acagatagaa cattgcattc agaataatga aaaacgcatc aaaaatggtg
    15781 cgttctgttt ttatgctacc ataaaaggag gaaaacaaat tgaaaatttt taagggagag
    15841 ttttatcgaa tctctgtatt aacagacaag ctagtaaggt tagaatactc tcgaactgga
    15901 aattttgagg atagaacgac acaacttatc tataatagag attttggcca agtttcgtta
    15961 gattatatcg agacatcaaa tgtactagat attatgacgg actattttca tctgcacttt
    16021 aataaaggag aatttaacgc cgaaaattta tttatagaat taaaaggaaa ttttgccgta
    16081 tatggtagtc gctggtattt tggtgaatct attgaaacgt taaaaggaac agctcggact
    16141 ctggataagg cagatggagc aatctcgtta gaagatggaa ttattagccg aaatggtata
    16201 gccttattgg atgattctca aggatttatt tgggatgaac aatctggtta tattgagaga
    16261 gaaaatcaaa ttgacctgta tttctttgcc tatgggcatg attatagagg agcaatcaga
    16321 gacttttacc atttgactgg ttcaacaccc ttgttgccaa gatatgcttt aggcaattgg
    16381 tggagtagat attggcctta tacgtcggat gaatacttgg atttaataga cagatttgaa
    16441 acagagaaaa ttccattatc tatcggtgtg ttagatatgg attggcatat aactgacatt
    16501 ccagctcgtt ttggaagtgg ctggacagga tatagttgga atagaaactt aataccaaat
    16561 ccagaacagt tattgcaaca acttcatgat agaaagttaa aactctcctt aaatgtccat
    16621 cctgctgatg ggatacgggc ttatgaagaa gcttatcctc aaatcgcaaa acgattgggg
    16681 ttaaatgtag aactagaaga acctgctatt tttgattttt ttaatccctc ttttagggaa
    16741 gcctacttta aagatgttca ttatgagtta gaaaagcagg gagtagattt ttggtggatt
    16801 gactggcaac aagggacaca aggtatgcta gatccacttt ggcttttaaa ccattatcac
    16861 tatcaggata gttgtaaaaa tgcagaaggt ggtttgattt tatcaagata tgcaggtcct
    16921 ggtagtcacc gctaccctgt tggtttttca ggggatacta ttattagttg gaattcctta
    16981 agatttcaac cctattttac agcgacagca tctaatatcg gttatagttg gtggagtcat
    17041 gatatcggtg gacatatgtt gggggattat gacgaagagc tacaaactag atggctacag
    17101 tttggtgttt ttagtccgat tactcgatta catagttcta gaagtccttt taatagtaaa
    17161 gaaccttggt ttttttcaga aacaacatct aagattatga agaaatacct ccgtttgaga
    17221 catcagatga ttccctatct atataccatg aatgtaaaga cacatgagga aggtgcccca
    17281 ttaatcagtc caatctatta tttctatcca gagaatgatg agagctataa tgttccaaat
    17341 caatactttt ttggaacaga actgatggtg gctcccattg tagaaaagat ggatttgaca
    17401 ttccaatctg caaaagtaga tgtatggttc cctgaaggtg aatggtatga ctttttttca
    17461 gagaaaaaat acacaggtgg tgtgaagtta agtgtttata gagacatctc gactacgcct
    17521 gtgtttgcaa aaagtggtgc aatcattccc ttggttggtt ctgagatagg tatgggtgtt
    17581 gatttacctg aagttgtaga ttggtatgta ttcccaggaa aacaacattc ttttgaaatg
    17641 cttgaagatc aaaatggtca aagatataaa acaagattat caatcgattg ggaaatggga
    17701 atggtagagt tagcattaca aggagattct agtatcgttc caagcaatag aaaacataga
    17761 attcatttta aaggaacgaa tgtgtctata attgaattgc caaataagaa tgatacagct
    17821 aaatttgaat ggaaagataa taaaaggaca tctttaaatg acgaagtttt tagactacta
    17881 aagacagctt ctcttccata tgaattaaaa gatagattgt taaatcaatt catcaatgcg
    17941 aaaaactctc atgacttaat gaatatcttg catcatcagg ataaggaatt gagagggcgt
    18001 ttgttggaaa tgatatttac tagccaaaac taattgaaat aattagaaag tcatttgttt
    18061 agtgtatatg aagattctgt atggtattcg ttatcactgg tcacattgaa aatgtgaaat
    18121 aagcacctac aacatagact ttacaacact tcatgtttta tatcatgggg tgtttttcta
    18181 tttaagtcaa agcccatcaa aaaatctcac tattcatcag gttaaaggaa acctaatcat
    18241 agtgagattg tgaattatag tagagtttgt atcgcctctt caatttgttt tgggtctgtt
    18301 tttgaagaaa agcgttcaaa gacttgccca tctcgaccga tgagaaactt agagaaattc
    18361 cattcgattc gttttcctag tgggccggat ttctggtctt ttaaccagac atagagaggg
    18421 tctgcttcct taccgttgac cttaatcttg gcaaaacgtg ggaaggtggt ttgaaaatgt
    18481 aggctacaga aggcgttgat ttcctctgcg ctgccgggtg cttgtcccat aaactgattg
    18541 caagggaaat ccaatatttc gaagccctga gcttgatagc gttcatagag ttcttgaagt
    18601 ccctggtact ggggcgttaa accacatcca gtagcagtgt tgacaatcaa gagaactttg
    18661 ccacgatagc tatccaaggg agttgcttgg ttgttttggt tcaaaacgga aaaatcataa
    18721 agtgaagtca tgagggcctc ttttcttttt ctacattgta acagttttta cttttttcgt
    18781 cgagtcggat ggaagatatt gttgaagaat aagtcttcaa tatgatagaa accgtttaca
    18841 aataacttta aaaatggtat gatttaatta aaccggttta cttagttgct ataaatctct
    18901 aatttgagat ttagttccta ttgattttac aatatgttta ttggagtgta tacatgcaaa
    18961 caaaaacaaa gaagctcatt gtgagtttgt cttcacttgt tttatcagga tttttattaa
    19021 accattatat gacagttgga gcggaagaaa cgactacgaa taccattcag caaagccaga
    19081 aggaagttca gtatcagcaa agggatacaa aaaatttagt tgaaaatggt gattttggtc
    19141 agacggagga cggaagcagt ccgtggacag gaagcaaagc tcaggggtgg tcagcttggg
    19201 tagaccagaa gaatagttct gcagatgcct caactcgagt cattgaggct aagggtgggg
    19261 ctatcactat ctcaagccat gagaaattaa gggcagcggt tcaccgtatg gttcctattg
    19321 aagctaagaa aaagtataaa ctgcgtttca agattaaaac agatcataaa gtcgggattg
    19381 ccaaggttcg tatcattgag gaaagtggta aggacaagcg attgtggaat tctgcaacga
    19441 cgtcaggaac aaaggactgg cagaccattg aagcagacta tagcccgact ttagatgttg
    19501 ataaaatcaa gctggagtta ttctatgaaa caggaactgg gactgtttcc tttaaggata
    19561 ttgagctggt agaggtagca gaccagcttt ctgaggattc tcaaacagat aaacagcttg
    19621 aggaaaagat tgatttacca attggaaaaa aacatgtttt ttctcttgcg gactatactt
    19681 ataaggtaga aaatcctgac gttgcttcag tcaaaaatgg aattttagaa cctcttaagg
    19741 aagggacaac caatgtcatt gtcagtaaag atggcaagga agtgaaaaag attcctttga
    19801 agattctagc ctctgttaag gatgcataca cagcccgttt ggatgactgg aatggcatca
    19861 tcgctgggaa tcaatactat gattctaaaa atgaacagat ggccaaatta aaccaggaat
    19921 tggaaggaaa ggtagctgat agcctatcta gtatttcaag tcaggcggac cgcacctatt
    19981 tgtgggaaaa attttcaaat tataaaatgt ctgcaaatct gactgccact tatcggaaat
    20041 tggaggagat ggccaagcaa gtgaccaatc cttcttctcg ttattatcaa gatgaaactg
    20101 tcgttcgaac agtcagggat tccatggaat ggatgcataa acatgtctac aatagtgaaa
    20161 agagcattgt tgggaactgg tgggattatg aaatcggtac acctcgtgcc atcaacaata
    20221 ccttgtctct gatgaaagaa tacttctctg atgaggaaat taaaaaatat acagatgtga
    20281 ttgaaaaatt tgtaccagat cccgaacatt tccgaaagac gactgataac ccatttaagg
    20341 ctctaggtgg aaacttagtt gatatgggaa gagtaaaagt aatagctggt ttactgcgta
    20401 aggatgatca agaaatttct tctaccattc gctcgattga gcaagtgttc aagttggtag
    20461 accaaggtga aggtttttat caagatggat cctatataga ccataccaat gttgcctata
    20521 cgggtgctta tgggaatgtt ttgattgatg gcctgtctca actgttgcca gtcattcaaa
    20581 agaccaagaa tccaatcgat aaagataaaa tgcaaaccat gtactactgg attgataaat
    20641 cgtttgctcc tttgctggtg aatggagagc tgatggatat gagtcgtgga cgctcgatca
    20701 gtcgtgcaaa tagcgagggg cacgtggccg cagtagaagt actaagaggg attcaccgaa
    20761 tagcggatat gtctgaagga gaaaccaaac aacgtttgca gagtcttgtg aagaccattg
    20821 ttcaatcgga tagttattat gatgtcttta agaatttgaa gacttataag gatatcagtt
    20881 tgatgcaatc cttgttaagt gatgcaggag tcgcaagtgt tccaagaaca agttacctat
    20941 ctgcctttaa caagatggat aaaacagcca tgtacaatgc agagaaaggg tttggatttg
    21001 gcttgtcact cttttccagt cgtaccttga attacgaaca catgaacaag gaaaataaac
    21061 gtggttggta tacgagtgat gggatgttct atctttacaa tggcgatttg agtcactata
    21121 gcgatggcta ctggccaaca gttaatccat ataagatgcc tggtacaaca gagacggatg
    21181 ctaagagagc ggatagcgat acaggtaaag ttttaccgtc tgctttcgtt ggaacgagca
    21241 aactagatga tgccaatgcg acagcaacca tggatttcac caactggaat caaacattga
    21301 ctgctcataa gagctggttt atgctaaagg ataagatcgc ctttttagga agcaatatcc
    21361 aaaacacttc aacagatact gctgcaacta caattgacca gagaaaactg gaatcaagta
    21421 atccatataa agtctatgtc aatgataaag aagcctccct tacagaacaa gaaaaggatt
    21481 atcctgaaac ccaaagtgtc tttttagaat catccgattc gaaaaagaat attggttact
    21541 ttttctttaa gaagagttca atcagtatga gtaaggcttt gcaaaaggga gcctggaagg
    21601 atatcaatga aggacagtca gacaaggaag ttgaaaatga atttcttacg attagtcagg
    21661 ctcataagca aaatggagat tcttatggct atatgctcat ccctaacgtg ggtcgtgcca
    21721 ccttcaatca aatgataaaa gagttagaaa gtagcctcat cgaaaataac gaaacccttc
    21781 agtctgttta tgatgccaaa caaggagttt ggggcattgt gaaatatgat gattctgtct
    21841 ctactatttc caaccaattc caagttttga aacgtggagt ctataccatt cgaaaagaag
    21901 gggatgaata taagattgcc tactataatc ctgaaaccca ggaatcagct ccagatcagg
    21961 aagtctttaa aaagctagag caagcagctc agccacaagt acagaattca aaagaaaagg
    22021 aaaaatctga agaggaaaag aaccattcgg atcaaaagaa tctccctcag acaggagaag
    22081 gtcagtcaat cttggcaagt ctagggttct tgctacttgg ggcgttttat ttattccgta
    22141 gaggaaagaa caactaattt gttcatcatc tagatgaatt acatgaaact gtggaaaata
    22201 gaaaaaatcc gaagaaggcc aaatatcttc ggatttttct tttaaaaaag gataagttga
    22261 tacttatcct ttttacttca ttatgtgact atagcgtttt gaaactagaa taggacatca
    22321 taactgctaa aagatttcta taaattcatt tgattttcct aatcaatttg ttcgtatcct
    22381 atttcactct actatattag tccgtctcgc acctcacgga gcgagacaaa acaaccaccc
    22441 gctatgcggg tgcgcgtcga aggttatacc aaaaaaactc caaacgcgat acaataaagg
    22501 tgttcaaccc acttgtaaag cgaaaggaga aaaaatatgg cacaaaaggc tcatagttta
    22561 tctcacacaa agtggaggtg ttctatcaca ttgtgttcac ccctaagtat agacgaaaag
    22621 tcatctataa tcaatataga agtagtttag gcgaaatatt tcatcgcttg tgtagttata
    22681 aaggtgttga aatgatcgag ggtcacttaa tgccagacca tgtacacatg ttagtcagta
    22741 ttccactaag gctaagtgtt tcgagtttca tgggttattt aaaaggcaaa agtgcactca
    22801 tgatgtttga caaacacgcc aatctcaagt acaagtttgg gaatcggcat ttctgggcgg
    22861 aaggttatta tgtaagtcca gtagggctta atgaagacac aattaagaaa tatagtcaag
    22921 attaaagaaa ttatcgagtg gatgatttct tcacgagtat gaaaatttga gaactagtaa
    22981 agtatgatat atagtaaaat gaaataagaa caggacaaaa tcgatcagga cagtcaaatc
    23041 gatttttaac aatgttttag aagtagaggt gtactattcc agtttcaatc tactatagca
    23101 ctagataaat tgagtgtaaa agaatatgag gatcccttta gggatagtgg taagtaatac
    23161 caaagtctct taaagaggca agtgacgagt caagagcaat aaggcttgaa caacgtgaaa
    23221 gccagcgtct ttaggcgctg gctgatgatt tgggcttata gctctgagat aaaccacccg
    23281 ttagacgggt agttatgatt ttatctgagt gtaacatact gttgggcaat ctcgctgatg
    23341 cggtcaaagt tgccttggga agcgagttta ttgagttcgc caccaattcc aacggcatct
    23401 gcaccagcag cgaaccattg agggatgttg tttagaccga ctcctccggt taccattacg
    23461 gaaacttgtg gaatcggtgc cttgactgca gagatatatg ctggactgag agtactacct
    23521 gggaagagtt tgatgatttc actaccggct tcaagtgcag tcgtgatctc tgtgagggta
    23581 atacagcctg gaatgtacgg tgtgctgtag agattgcaca ttttcgcagt ttcagcatgg
    23641 aaagatggag aaacaacgta atttgctccg gctagaatgg catctctagc agttacggca
    23701 tcaagcacag tacctgcacc gatacaaaca ctctgatcgt cctgatacaa gtctacaagt
    23761 tccttgatga tttgtcctgc atactgattg gtataggcga tttcaatagc tttgataccg
    23821 cccttgatac aagcaatcga ggcttgtagt ccttcttcct ttgtatttcc tcgaatgaca
    23881 gcaacaattt tctgtttttt tagttcaata attgtatctg atttggtcat gtaattctcc
    23941 taacgaatga tatcttgtgc atttgccagt aaattttcaa tactagttgc ggaagtggag
    24001 agatggtctc ctggaagagt gcatttgaga gttgcgctcg caactgcaaa gtcaatggta
    24061 gtttttaggg aggaatgatg gagtagttgg taaagggcac cagatataaa ggcatccccg
    24121 ctaccaattc gttgatagac tgcagttttt agttggacag actcttcaaa tcgttcttcc
    24181 agagcatagg cttgatagac atttttgtct tgctcatcac tagagcggag ggtatggaaa
    24241 atggccttga aaccataggc ttcttttaaa agtcgcatgc gattttccac ctcttctagg
    24301 ctagcactgt ctcttggaaa catctctaga ttttggtcat caatcatgag aggatcaata
    24361 ccgaagcaat agtcagtaaa acgtgcaaac ttagaaaatt catacttggc ttctaggact
    24421 gaaatcatct ttgttctcag attgagatcc attgaaacga caattcctcg gcgcttggct
    24481 tcttccaaga gtaggagaag gatcgcacgg acctcttgac cgatagctac ggtgattcca
    24541 ctaaaatgaa aatggctaat cccctgaaag agagaatcca tatctagcat gtttggccga
    24601 atctggctga tactcgtatg cttacgatcg tagaaaactt cactttgacg acaaccaaag
    24661 ccgttctcca aatagtagag gccgattcga tcgccaagcc gacagattga actggtatcg
    24721 atttggtgct gtttcaagaa tgtgagaaaa cgatctccaa tctcgttggc agggagtgcg
    24781 gtaaagactt tcgttgagat acccagggct tgcaaattac aagcgatgtt aatttctgat
    24841 ccgccaaaat aagtcgaact ggcaacatga tctccgatac tggtggcatc taatggtgag
    24901 attcgaatta atggttcgcc aaacagtaat attttcgtca tccattagtt cctttctggt
    24961 ttagaatagc tttacttggc taatacttct ttcaaataag cagcgacttc atcatcttgg
    25021 cagttttcaa agaagtattc ttggaagtat ttgccagata tggtgtcttt gaggaagtct
    25081 tggtcgattg ttttaaggat ggtcatcaaa tcattgtggg tgatttgttt cacctcgttt
    25141 aagatacgag cgttgcgttg ttcagggatt acacgttctc ttgggtagcc accgcccatt
    25201 tcttcagcaa ataagcgttc aaacatcaat ttgagggtca gttctgcccc ccagccaaat
    25261 cctttggcat aagggataga caaggcgtta ccaccattga tttgagaata aaggtaagcg
    25321 tcagttgggt ccactgctag accacagaca acaccaggga agctgtttaa agcaagcata
    25381 gcccctacac ccgtaccaca gccggtaaca acaaagtcaa ctgcctttgt atttaaaagg
    25441 atggcagcca ttagtccgtt ctgcacataa gttaattgac tttctccttc ttctccacgc
    25501 ataccatagt taaataattg gtagtctttt ttatctgtcg cttcttttag actatcgtaa
    25561 ataatgtgat tcttgctagc ttgactattt tcattgatta atgcgatttt cataagatct
    25621 tctttctatt tttactcagg ttgttttccg atgtaggcta agataccgcc atctacatat
    25681 aggatgtggc cattgacaaa attgctggca tcactagcga gaaagacagc agggcccatc
    25741 aaatcttcag gatttcccca acgtgcagca ggtgtttttg caatgatgaa ctggtcaaat
    25801 gggtggcgag aaccatcttc ttgcaactca cgaagaggtg ctgtttgagg agtggcaata
    25861 taacccggtc caattccgtt acattggata ttggctccac cgtattcaga cgcaatgttg
    25921 cgggtcaaca ttttcaagcc ccctttagca gcagcataag cgctaactgt ttcacgtccc
    25981 agttcgctca tcatcgaaca aatattgata atctttccat gccctttctt tatcatagaa
    26041 ggaataactg cctttgaaac gataaatggt gcgtttaagt caatatcgat gaccttacgg
    26101 aaatcagcgg cgctcatttc gcacattgga actcggcgga taataccagc gttattaacg
    26161 aggatgtcaa tgacaccaac ctcttgttcg atttgcttga ccatggcttg gataccgtcc
    26221 tcgtctgtca cgtcacagac atatccatgg gcttcgatgc caacttcacg ataagcttca
    26281 atccctttat tgaccagatc ttgattgata tcgttaaaga caatagtagc gccggcttca
    26341 gcgtaggatt tggcaatagc aaatccaatt ccataagaag cgccggtgat gagagcaatt
    26401 tttcctttta aagaaaactg ctcaattgag aatgatgtat ttgtcatttg atacttcctt
    26461 tcaaatttgt taagacttct ctataa
//
LOCUS       DAVLBE010000025        25950 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.025, whole genome shotgun sequence.
ACCESSION   DAVLBE010000025 DAVLBE010000000
VERSION     DAVLBE010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25950)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25950)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25950
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.025"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            436..1146
                     /gene="deoD"
                     /locus_tag="VXB91_001142"
     CDS             436..1146
                     /gene="deoD"
                     /locus_tag="VXB91_001142"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEV0470608.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLDDAVCFNEVRN
                     MFGYTGTYKGHRVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKELGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(1169..1693)
                     /locus_tag="VXB91_001143"
     CDS             complement(1169..1693)
                     /locus_tag="VXB91_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HEV0470609.1"
                     /translation="MKITIIGYSGSGKSTLAEKLSNYYSIPKLHMDTLQFQPGWQDSD
                     CEWMLTEIKNFLTKHKAWVIDGNYSWCYYQERMQEADQIIFLNFLPLTCLFRAFKRYL
                     KYRGKVRESMAADCPERFEWEFIRWILWDGRSKTQKENYQKLCQEYSHKVTILRNQRE
                     LDQFLDKKRKSYNS"
     gene            complement(1746..1982)
                     /locus_tag="VXB91_001144"
     CDS             complement(1746..1982)
                     /locus_tag="VXB91_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HEV0470610.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSTKLAK"
     gene            complement(2050..2970)
                     /locus_tag="VXB91_001145"
     CDS             complement(2050..2970)
                     /locus_tag="VXB91_001145"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HEV0470611.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEVYDIVPEKKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVESFAHQVWISINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            3160..3563
                     /locus_tag="VXB91_001146"
                     /pseudo
     CDS             3160..3563
                     /locus_tag="VXB91_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            3779..4360
                     /locus_tag="VXB91_001147"
     CDS             3779..4360
                     /locus_tag="VXB91_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV0470612.1"
                     /translation="MYYAENPDAAHDIHELRVDLLGEKMTFLTDAGVFSKKMVDFGSQ
                     LLLKCLDVNQGETVLDVGCGYGPLGLSLVKVYGVQATMVDINTRALDLAQRNAEKNNA
                     KATIFQSNIYARVQGRFDHVISNPPIRAGKQVVHEIIEKSKDFLEIGGDLTIVIQKKQ
                     GAPSAKSKMEDVFGNCEILKKDKGYYILRSVKE"
     gene            4357..5634
                     /locus_tag="VXB91_001148"
     CDS             4357..5634
                     /locus_tag="VXB91_001148"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HEV0470613.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLIEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIRGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVRQHLENGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDVLDYETGIVFEKKIGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            5652..6314
                     /gene="deoC"
                     /locus_tag="VXB91_001149"
     CDS             5652..6314
                     /gene="deoC"
                     /locus_tag="VXB91_001149"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HEV0470614.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYGFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSTVKAFETKEAIQNGADEIDMVINVGALKSGDL
                     ALVESDIRAVVEASGDKLVKVIIEACLLTDQEKVLACQLAQKAGADFVKTSTGFSTGG
                     ATIADVRLMRETVGPDMGVKAAGGARSYADALTFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            6301..6690
                     /locus_tag="VXB91_001150"
     CDS             6301..6690
                     /locus_tag="VXB91_001150"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEV0470615.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGSVYTGVNIE
                     NASYPLTNCGERTAIFKAISEGQREFSELIVYGQTEKPISPCGACRQVMVEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            6781..7833
                     /locus_tag="VXB91_001151"
     CDS             6781..7833
                     /locus_tag="VXB91_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HEV0470616.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQDWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALHNAVEEAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDISNKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            7977..9512
                     /locus_tag="VXB91_001152"
     CDS             7977..9512
                     /locus_tag="VXB91_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0470617.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEIAGAINADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SVGHVPEDRHRDGLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQGLGVLMAGGNLGKEK
                     SDV"
     gene            9505..10563
                     /locus_tag="VXB91_001153"
     CDS             9505..10563
                     /locus_tag="VXB91_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0470618.1"
                     /translation="MSKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLAELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            10566..11522
                     /locus_tag="VXB91_001154"
     CDS             10566..11522
                     /locus_tag="VXB91_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0470619.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGVIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
     gene            11607..12956
                     /locus_tag="VXB91_001155"
                     /pseudo
     CDS             11607..12956
                     /locus_tag="VXB91_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(12999..13640)
                     /gene="plsY"
                     /locus_tag="VXB91_001156"
     CDS             complement(12999..13640)
                     /gene="plsY"
                     /locus_tag="VXB91_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HEV0470620.1"
                     /translation="MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
     gene            13776..15719
                     /gene="parE"
                     /locus_tag="VXB91_001157"
     CDS             13776..15719
                     /gene="parE"
                     /locus_tag="VXB91_001157"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HEV0470621.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KIGTAPKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGFKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLAVVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVVNTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEEATVF"
     gene            16139..18610
                     /gene="parC"
                     /locus_tag="VXB91_001158"
     CDS             16139..18610
                     /gene="parC"
                     /locus_tag="VXB91_001158"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HEV0470622.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKNTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLA
                     AIIGDERTMYNLMKKELREVKKKFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEEILYVEVLDQFDDATTYFAVTRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEDK"
     gene            18742..19764
                     /locus_tag="VXB91_001159"
     CDS             18742..19764
                     /locus_tag="VXB91_001159"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HEV0470623.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGTGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            19820..20524
                     /locus_tag="VXB91_001160"
     CDS             19820..20524
                     /locus_tag="VXB91_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0470624.1"
                     /translation="MVLSTSAILVACGKTDKEADAPTTFSYVYAVDPASLGYSIATRT
                     SRTDVIGNVIDGLMENDKYGNVAPSQKDYDLNSTGWAPSYQDPASYLNIMDPKSGSAM
                     KHLGITKGKDKDVVAKPGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMP
                     TASSGGSPVVSNVVPFSKPYSQVGIKGEPYIFKGMKLQKDIVTTKEYNEVFKKWQKEK
                     LESNSKYQKELEKYIK"
     gene            20589..21278
                     /locus_tag="VXB91_001161"
     CDS             20589..21278
                     /locus_tag="VXB91_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HEV0470625.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            21275..22198
                     /locus_tag="VXB91_001162"
     CDS             21275..22198
                     /locus_tag="VXB91_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HEV0470626.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMSNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            22213..22857
                     /gene="pcp"
                     /locus_tag="VXB91_001163"
     CDS             22213..22857
                     /gene="pcp"
                     /locus_tag="VXB91_001163"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEV0470627.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            23025..23255
                     /locus_tag="VXB91_001164"
     CDS             23025..23255
                     /locus_tag="VXB91_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HEV0470628.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            23305..23385
                     /locus_tag="VXB91_001165"
     tRNA            23305..23385
                     /locus_tag="VXB91_001165"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:23339..23341,aa:Tyr,seq:gta)
     gene            23395..23466
                     /locus_tag="VXB91_001166"
     tRNA            23395..23466
                     /locus_tag="VXB91_001166"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:23427..23429,aa:Gln,seq:ttg)
     gene            23628..24830
                     /gene="rpsA"
                     /locus_tag="VXB91_001167"
     CDS             23628..24830
                     /gene="rpsA"
                     /locus_tag="VXB91_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HEV0470629.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFIDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRAARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
     gene            complement(24915..25950)
                     /locus_tag="VXB91_001168"
                     /pseudo
     CDS             complement(24915..25950)
                     /locus_tag="VXB91_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436408.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         7822 a         4573 c         5862 g         7693 t
ORIGIN      
        1 ggtttgaaga gattttcgaa gagtataaac agaaaggtag agcgcgtgtt ctaatttgaa
       61 cacgagtaga aaacttttct aaaaacaaaa acgaaaggat gggtaaactg tattcgctga
      121 actgaatacg ggcgactctc ctctaaatca aaattaagaa agaaaggaat tgaccccacc
      181 ctaaaagcag tgggaaaaag atagttggtc tagcgagcat cgctcactgc gcccaactcc
      241 tattttccct tcgctttttg acgggtttgg tatctttctc aatataaaat ataaaataaa
      301 gaaaggtaga gcgtgtgttt tgatttgaac acgagcggaa aactcggaaa atagataatc
      361 tgactgaaaa atcaggattt ctcgtcggct tcctaatttt cagtcgtttt cttctcgctc
      421 tttgtatcat aaattatgtc tatccatatt gctgctcagc agggtgaaat tgctgataaa
      481 attcttcttc ctggggatcc tcttcgtgct aagtttattg cggagaattt ccttgatgat
      541 gctgtttgtt ttaacgaagt gcgtaacatg tttggttaca ctggtactta caagggtcac
      601 cgtgtatctg tcatgggaac tgggatggga atgccatcta tttcgattta tgcgcgtgag
      661 ttaatcgtag actacggtgt gaagaaattg attcgtgtgg gaactgcagg ttctttgaat
      721 gaagaggttc atgttcgtga attagttttg gcgcaggcgg ctgcaaccaa ctcaaacatc
      781 gttcgtaatg actggccaca gtacgatttt ccacaaattg ctagctttga tttgcttgat
      841 aaagcctacc atatcgccaa agaacttggt atgactactc acgttgggaa cgttttgtca
      901 tctgatgtct tttactcaaa ttactttgaa aagaatatcg agcttggtaa atggggagtc
      961 aaggctgtgg aaatggaagc agcagctctt tactatcttg ctgcccaata ccatgttgat
     1021 gcgctagcta tcatgaccat ctctgatagc ttggtcaatc cagacgaaga cacaactgca
     1081 gaagaacgtc aaaatacctt cactgatatg atgaaggttg gtttggaaac cttgattgca
     1141 gaataattat agccaaaaag gaagcccttt atgaattgta ggacttcctt ttcttatcca
     1201 gaaattgatc tagctctctc tgatttcgaa gaatagtgac tttatgtgaa tattcttggc
     1261 aaagtttttg gtaattttct ttttgagttt tgctacgccc atcccaaaga atccatctga
     1321 taaactccca ctcaaagcgt tcagggcaat ctgccgccat actttctctg acttttccac
     1381 ggtatttaag ataacgctta aaggctctaa agagacaggt caatggcaaa aaattgagaa
     1441 agatgatttg gtcagcttct tgcattcgtt cttggtagta gcaccaagaa taattaccat
     1501 cgatgaccca agctttatgc ttggtgagaa agttttttat ctcggttaac atccattcgc
     1561 agtcactgtc ttgccaacca ggttgaaatt ggagtgtgtc catgtgcagt tttggaatgg
     1621 agtagtagtt agataacttt tctgctagag ttgacttacc agaaccagaa tatccgataa
     1681 ttgtgatttt cattttctac cttttcctat ttggagacaa aaaaacagcc tctatggact
     1741 gtttcttatt tagcaagttt agttgaaaga cgagctttat cgcggcttgc tttgtttttg
     1801 tgaatcaaac ctttagtttc tgctttatcg atagctgagc tagcagcacg gaaaagttct
     1861 tcagatgggt ttgcttcgaa agcttttata gcagtacgca tagctgattt ttgagctgag
     1921 ttcttttcgt tttgtttaac gttcaattca gcgcgtttga tagctgattt aatgtttgcc
     1981 aatgttctta cctccatatt tactaactat accattatat atgaaaactt acgttttgac
     2041 aagggaaaat tactttttta agtaaatttc atcgatttca tggttcttgc ttttatgaag
     2101 aatcacttct gcacgatttc tggttggttc aatataattt tgcagatttg tgagattgat
     2161 actgatccag acctgatggg caaaggactc cacttcccca atcggcatct gagtaaaacg
     2221 ataatagtag ctatcagggt cgttttgggc taggctcagc atcttcaaga aacggtccag
     2281 ataccaactt tcaatatcat ctactccagc atctacatag atggaaaagt caaagaagtc
     2341 agtgatatag agacgatcgt tttgtggatt ttgaaagaca ttaattccct caacaattac
     2401 aaaatcagca gctttgacac tttgtttctt ttcgggtacg atgtcgtaaa cttcatgaga
     2461 atagacagga atatctacat cttgtccatt tttgatgcgg tccaagaagt tgagaagagc
     2521 ttccatatca tagctttcag gaaatccttt acgatttaaa atcccctgct caatcaaggt
     2581 ttgattggga tagagaaaac catcagttgt aaccaactca accgtagcat ctgtaaacgt
     2641 acgggacagt aggatttgaa gtaggcgact ggttgtggat tttccaacgg caacactccc
     2701 agaaacccca ataataaaag gttgagattt actttcacgt tggaggaaaa ttccttttga
     2761 aaaggctaaa tcttccttag ttcgcttgta aatctgaatc agatgagcca aggggagata
     2821 gatatctgta acgtcttgga gactgatttg gtcattaaaa ctcttgatag attccaattc
     2881 ttcttctgtc aaaggaggtg ttgtctttcg atgtaaagat tgccaagtct ggcggctgat
     2941 tttttcaaaa tgtaaaaatt cgttggtcat ttgttttccc ctagatattt tgtctatcat
     3001 accataaaaa gctaaaaaaa taaagcggtt tcttgaatgt ggtaagtcaa tggtatatag
     3061 tataagtgat caatttattg atgaaatagg agatagattc tactgattta taagcttata
     3121 aagggggctt tttagttcac aacttatagg aggtgtacta tgaaaatctt aaaacgttac
     3181 atattggaac tctgttttat tttaagtttt gctttacctt ttataaaagg aaccaatgca
     3241 gataatggta gatgctttgt ggaaacctat tacggtttta cttttttgat ggaacatgct
     3301 attgtaacag ctgtctttat ctgttcgttc ttaattgctt tcttactaaa aaacgatgga
     3361 cgaaatggat tgctgcgggt agttattgct ttttagtcct acggattgcg acagagggtt
     3421 atttcttcca catgtcacta gaagatttga tacgactttg gacaagtttg gaaatcctga
     3481 cacaaacgta tcagttgggc ttttatctaa acattttgtt aggaattttg ttgataataa
     3541 agtattttaa ggttaagcaa tagaaataat aatctgcctg attatagatg ataaactttt
     3601 tgtttttatc tggactgtga tatttatagt tctaaatggt ttattattta taagtgttga
     3661 aagagattga agaaaatggc ttcgtgactt gctttcttcg gtctttttcg ttttattatc
     3721 aatttgtaaa cgatttacaa tttgagtcaa attatggtaa aatagtgtca tgagtaaaat
     3781 gtactatgca gaaaatcctg acgctgctca cgacattcat gagttgagag tggacttgtt
     3841 gggagaaaaa atgacttttt tgacagatgc gggtgttttt agcaagaaaa tggttgactt
     3901 tggaagtcaa ctcttgctca agtgtctgga tgtcaaccaa ggagagacag tcctagatgt
     3961 aggctgtggt tatggtccat taggtttgtc cttggtcaag gtttacggag ttcaggcgac
     4021 catggttgat attaacactc gtgccctgga tttagctcag agaaatgctg aaaaaaataa
     4081 tgcaaaagcg acgatatttc aatctaatat ttatgcaaga gttcaagggc gatttgacca
     4141 tgtcatttcc aatcctccta tccgtgcggg caagcaagtc gttcatgaaa tcatcgagaa
     4201 aagtaaagat ttcttggaaa ttggtggaga tttgaccatc gtcatccaga aaaaacaagg
     4261 agctccaagt gccaaatcta agatggaaga tgtgtttggc aattgtgaaa tccttaaaaa
     4321 agacaaggga tactatatcc ttagaagtgt gaaagaatga gagcagttga tttaatccaa
     4381 aaaaaacgag acggtcaaga actgacttca agtgaaattg aatggctgat agaaggctat
     4441 gtatcaggaa ctgttcctga ttatcagatg tctgcctttg ctatggctgt ttattttaaa
     4501 ggaatgacga ctcgagaaat ctctgattta acgatgaata tggttaagac tgggcaagag
     4561 tttgacctgt cagccattga tggtgtgaaa gttgacaagc attctactgg tggtgtcggc
     4621 gataaggtaa ccttgatttt agctcctctt gttgctagct tcggtgtgcc tgtagcaaaa
     4681 atgagtggtc gtggtcttgg ccatacaggc ggaacaattg ataaattgga gtccattagg
     4741 ggctatcaag tagaacgtag tcaagaggat tttattcgtc aggttcagga tattggagta
     4801 tctgtcattg ggcaatcaga ccagctggtc aaagcagata agcttctcta tgcccttcgt
     4861 gatgtgaccg caactgtcga cacgattcct ttgattgcga gttcggtgat gagcaagaaa
     4921 attgcggcag gggcggatgc tattttgcta gacgtgactg tcggtgaggg tgccttcatg
     4981 aagacggttg atgaggcgcg tgagttggct caaactatgg tagatcttgg taaggttgtt
     5041 ggacggaaga cagtagcagt gattacggat atgagccagc ctttggggcg agcgattgga
     5101 aatcgtctgg aaatccttga agcattggag attttgcaag gtcaaggacg tcaggatatt
     5161 acccacttta tttgtgaatt ggctcaaatt atgcttggtt tggcaaatgt taacaaaact
     5221 gttgaagaag ttcgccaaca tcttgaaaat ggtcaagcac tggctaagtt tgaggaaatg
     5281 gtgcaagccc aaggtggaga cttggaagac ctctatcgtc ctgtaaatgt agctcatgtg
     5341 gtggaaatcc ctgctcagga aacgggtgtc atttcagctc ttccagctat ggactttggt
     5401 ctttatgcca tgaggctggg tgctggtcgt gcagttaagt ctgatgtctt ggactatgaa
     5461 acaggaattg tttttgaaaa gaagattgga gactccgttc aaaagggtga aattgttgca
     5521 aaagtataca caaatgaaaa aattccacct caactagtta cagatttcca aaaatgtgtt
     5581 aaaataagtg atgaagtgaa aaaaatccgt gaaattgtag aaatcatctc ctaaatggag
     5641 ggaaaaccga aatgaaatta aataaatata tagatcatac gcttttaaaa caagatgcaa
     5701 agaaaaaaca aattgatagt ttgttgtctg aggctagaga gtatggcttt gccagtgttt
     5761 gcgttaatcc gacctgggtt gaacatgcta aaaaaggact tgaaggcaca gatgttaagg
     5821 tttgcacagt agtaggtttc cccttgggag caacaacttc aactgtgaaa gcttttgaaa
     5881 caaaagaagc tatccaaaat ggggctgatg agattgacat ggtaatcaat gttggggctc
     5941 tcaagtcagg tgatttggcc ttggttgagt cggatattcg tgcagtagtg gaagcaagtg
     6001 gggacaagtt agtgaaagtt attattgaag cttgccttct gacagaccaa gaaaaagttt
     6061 tggcttgcca attagcccaa aaagcaggag ctgactttgt caaaacatct actggctttt
     6121 caactggtgg tgctacgata gcagatgtta gattaatgcg tgaaacagtt ggacctgata
     6181 tgggtgtcaa ggccgccggt ggagctcgtt cttatgcaga tgctcttacc tttgtcgaag
     6241 caggtgcgac ccgtatcgga acgtcagctg gggtagctat tttaaaagga gaattggcag
     6301 atggcgacta ctgagttgat tgaactggca attgaaacca gcaaacatgc ctatgtcccc
     6361 tattctcact ttcctatcgg agcagtttta gtagccaaag acggaagtgt ttacacggga
     6421 gtgaatatcg aaaatgctag ctatcctttg accaattgcg gtgagagaac agctattttt
     6481 aaggctatat ctgaaggcca aagagaattt tcagaattga ttgtctatgg tcaaactgaa
     6541 aaaccgattt caccatgtgg tgcttgtcgc caagtaatgg tcgaattttt tgaacaagat
     6601 ttaaaagtga ccctagtcgc aaaagataaa tcgacggtcg agatgacggt cggggagtta
     6661 cttccatact cttttacaga cttaaattag tctgagtcgc tctttgagtg gcaagggtct
     6721 ttgtgaccaa tcaatccata cttgcaacat cgttgcacat cttatttagg aggttcagta
     6781 atgaacaaga aacaatggct aggtcttggc ctagttgcag tggcagcagt tggacttgct
     6841 gcatgtggta accgctcttc tcgtaacgca gcttcatctt ctgatgtgaa gacaaaagca
     6901 gcaatcgtca ctgatactgg tggtgttgat gacaaatcat tcaaccaatc agcttgggaa
     6961 ggtttgcaag actggggtaa agaacacaat ctttcaaaag ataacggttt cacttacttc
     7021 caatcaacaa gtgaagctga ctacgctaac aacttgcaac aagcggctgg aagttacaac
     7081 ctaatctttg gtgttggttt tgcccttcac aatgcagttg aagaagcagc taaagaacac
     7141 actgacttga actatgtctt gattgatgat gtgattaaag accaaaaaaa tgttgcgagc
     7201 gtaactttcg ctgataatga gtcaggttac cttgcaggtg tggctgcagc aaaaacaact
     7261 aagacaaaac aagttggttt tgtaggtggt atcgaatctg aagttatctc tcgttttgag
     7321 gcaggattca aggctggtgt tgcgtcagta gacccatcta tcaaagtaca agttgactac
     7381 gctggttcat ttggtgatgc ggctaaaggt aaaacaattg cagccgcaca atacgcagcc
     7441 ggtgcagata ttgtttacca agtagctggt ggtacaggtg caggtgtctt tgcagaggca
     7501 aaatctctca acgaaagccg tcctgaaaat gaaaaagttt gggttatcgg tgttgaccgt
     7561 gaccaagaag cagaaggtaa atacacttct aaagatggca aagaatcaaa ctttgttctt
     7621 gtatctactt tgaaacaagt tggtacaact gtaaaagata tttctaacaa ggcagaaaaa
     7681 ggagaattcc ctggcggtca agtgatcgtt tactcattga aggataaagg ggttgacttg
     7741 gcagtaacaa acctttcaga agaaggtaaa aaagctgtcg aagatgcaaa agctaaaatc
     7801 cttgatggaa gcgtaaaagt tcctgaaaaa taatggatgg aagtcatttc ttaggaagcg
     7861 gccaagggcc gcttttttaa gagttgagac aaagtcattt tgtctcagta aagcttgcta
     7921 ctagacaaac tagcaagttt tattgaaata aaataagact ctgaaaggaa gagcacatgg
     7981 cacacgaaaa tgtcattgag atgcgtgata ttaccaaggt gtttggtgga tttgttgcca
     8041 acgacaaaat caacttgcac ctacgaaaag gtgaaattca tgcactttta ggagaaaatg
     8101 gggctggtaa gtccacgcta atgaacatgt tagcaggcct tcttgaacca accagtggtg
     8161 aaatcgcggt caacggtcaa gttgtcaatc tcgactcccc atctaaagca gctagcttgg
     8221 gaatcgggat ggttcaccag cactttatgt tggttgaagc cttcacagtg gctgaaaaca
     8281 tcattttagg tagtgaattg actaaaaatg gtgtgctaga tatcgctgga gctagcaaag
     8341 aaatcaaggc tctttctgaa cgttatggct tagctgttga cccttctgcc aaggtagcag
     8401 atatctcagt tggagcccaa caacgtgtag aaattttaaa aacactttat cggggggctg
     8461 atatccttat ctttgacgaa ccaacggctg ttttgactcc atcagaaatt gatgagttga
     8521 tggctattat gaaaaatctt gtcaaagaag gaaaatcaat tatcttgatt acccacaaat
     8581 tggatgaaat tcgcgcagtt tctgaccgtg ttacagttat ccgtcgtggg aaatcaattg
     8641 aaaccgttga aattgcaggg gctatcaatg ctgatttggc ggaaatgatg gtaggacgtt
     8701 ctgtttcctt taaaacagag aagcaagcct ctaaaccaaa agaagtggtt ttgtctatca
     8761 aagatttggt ggtcaatgaa aaccgtggtg ttccagctgt taaaaatctg tccttggatg
     8821 ttcgtgctgg agagattgtt ggtattgcgg ggattgatgg aaatggtcag tctgaactga
     8881 ttcaagccat tacaggtctt cgtaaggttg aatctggtag cattgagcta aaaggagatt
     8941 caattgtagg cttgcaccca cgtcagatta cagaactaag tgttgggcac gttccagaag
     9001 accgtcaccg tgatggcttg attttggaaa tgatgatatc tgaaaatatt gcccttcaaa
     9061 cctactataa agaaccacat agtaaaaatg gaattttgaa ttattcaaat attacttctt
     9121 atgctaaaaa gctgatggaa gagtttgatg ttcgcgctgc cagtgaatta gttcctgcag
     9181 ctgcactctc aggaggaaat caacaaaaag caattattgc tcgtgaaatt gatcgagatc
     9241 ctgatctcct tatcgttagc cagccaactc gtgggttgga tgtcggtgcc attgagtata
     9301 tccacaaacg cttgattgaa gagcgtgata atggcaaggc tgtccttgtt gtcagctttg
     9361 aattggatga gattttaaac gtctcagacc gtattgccgt tatccacgat ggtaagattc
     9421 aaggtattgt atcaccagaa acaaccaata aacaaggact tggtgtcttg atggctggtg
     9481 gaaacttggg aaaggagaag agtgatgtct aaaaaattac aacaaatttc ggttcccttg
     9541 atttctgtat tcctaggaat tttactcgga gccattgtca tgtggatctt cggttatgat
     9601 gctatttggg gctacgaaga attgttctat acagcctttg gcagtctgcg tgggattgga
     9661 gaaatcttcc gtgctatggg tcctctggtc ttgattggtc ttggttttgc ggttgccagt
     9721 cgagctggtt tctttaacgt cggacttcct ggtcaggctt tggcaggttg gattctcagt
     9781 ggttggtttg ccctgtcgca tccagatatg ccccgtccct tgatgattct agcaaccatc
     9841 gtgattgcct tgattgctgg tgggattgtc ggagcgattc caggtattct tagggcctat
     9901 ctagggacgt cagaggttat tgtaaccatc atgatgaact acattgtctt gtatgtaggg
     9961 aatgccttta tccatgcttt ccctaaagac ttcatgcaaa gtacagattc gaccattcgt
    10021 gttggggcta atgcaaccta tcagacacct tggttagctg agttgactgg taactcacgg
    10081 atgaatattg gtattttctt tgccatcatt gccgttgcag ttatttggtt catgctcaag
    10141 aaaacaactc ttggttttga aatccgtgca gttggtctta atccacatgc ttcagaatat
    10201 gctggtattt ctgccaagcg gactattatc ctatctatga ttatttcagg tgccttggca
    10261 ggtcttggtg gagctgttga aggtttggga accttccaga acgtctatgt tcaaggttcg
    10321 tcattagcta tcggatttaa cggaatggcg gttagtttgc ttgcggccaa ctcaccaatt
    10381 ggtatactct ttgcagcctt cctatttggc gttctccaag ttggggctcc tggtatgaat
    10441 gcggcgcagg taccatctga gctcgtcagc attgtaacag cgtctattat cttctttgtc
    10501 agtgttcatt accttatcga acgctttgtc aaaccgaaaa aacaagttaa aggaggtaag
    10561 taaagatgtc tattataacc ttgctccccc tcttggtgtc ttctatgctg atttactcag
    10621 cacctctcat ctttacaagt atcggtggtg ttttctctga acgtggtggt gtggtaaacg
    10681 ttggccttga aggaattatg gttatgggtg ccttttctgg agttgtcttt aaccttgaat
    10741 ttgcagaaca atttggagca gcaactccat ggctatcctt gcttgtagca ggattggttg
    10801 gtagtgtttt ctctatcatc cacgcagcag cgacggttca tttccgtgca gaccatgttg
    10861 tcagcggtac ggtattgaac ttgatggcgc ctgccttggc tgttttctta gttaaagttc
    10921 tttataacaa aggacaaacc gacaacctaa gtcaaacttt tggacgcttt gatttcccag
    10981 tcttggcaaa tatcccagtg attggtgata tcttcttcaa gtcaactagt ctacttggtt
    11041 atctggcgat tgccttctca ttccttgctt ggtttattct ctttaagact caatttggtc
    11101 ttcgtctccg ctctgtcggt gaacatcctc aagcagcgga taccttggga atcaacgtct
    11161 acaagatgag atatttaggg gttattattt caggttttct aggtggaatt ggcggagcga
    11221 tttatgcgca atcaatctca gttaacttct cagtgacaac tattgttgga cctggattta
    11281 tcgcccttgc tgcgatgatc tttgggaaat ggaatccaat cggtgctatg ctttctagtc
    11341 tcttctttgg actttcacaa agtttggctg ttatcggttc tcaattgccg ttcctacaag
    11401 gagtgccagc ggtttatctt caaattgcac cttatgtttt gacaattctt gtcttagcag
    11461 ccttctttgg aaaagcagtc gcaccaaaag cagatggtat caactacatc aaatcaaaat
    11521 aagcatacaa aaaaacgtca gtccaatgac tgaactgccc cccaaaagtt agacagaaaa
    11581 aatctaactt ttggggtgtt tttattatga aattaactta tgatgataaa gttcagatct
    11641 atgaacttag aaaacaagga tatagcttag agaagctttc aaataaattt gggataaata
    11701 attctaatct tagatatatg attaaattga ttgatcgtta cggaatagag ttcgtcaaaa
    11761 aaggaaaaaa tcgttactat tctcctgatt taaaacaaga aatgattaat aaagtctgac
    11821 atgaaggctg gactaaagac agagtttctc ttgaatacgg tctcccaagt cgtacgatac
    11881 ttcttaactg gctagcacaa tacagaaaaa aacgggtata ctattgttga gaaaacaaga
    11941 gggagagtac ctaaaatggg acgtaagcca aaaaagagac ctgaagagag gacagaatta
    12001 gaacatcttc aagcagaaaa tgagtacctg agagcggaga atgccatcct aaaaaagtta
    12061 agagaactcc gattgaagga ggaaaaagag aaagaagaaa gacagaaatt gttcaagaat
    12121 taatgactga gttttcgtta gatattcttc taaaagccat taaactagct cgttcgacct
    12181 actactatca cttgaaacag ctagacaaac cagataagga ccaagagctt aaagctgaaa
    12241 ttcaatccat ttttatcgaa cacaagggaa attatgctta tcgtcggatt tatttagaac
    12301 taagaaatcg tggttatctg gtaaatcata aaagagttca aggcttgatg aaagtactca
    12361 atttacaagc taaaatgcga cagaaacgaa aatattcttc tcataaagga gacgttggta
    12421 agaaagcaga gaatctcatt caaggccaat ttgaaggctc taaaacaatg gaacagtgct
    12481 acacagatgt gactgaattt gccattccag taagtactca aaagctttac ttatcaccag
    12541 ttttagatgg ttttaacagc gaaattatcg cctataatct ttcaacttca cccaacttag
    12601 aacaagtaca aacaatgttg gaacaggcat tcacagagaa gcactacgag aatacgattc
    12661 tccatagtga ccaaggctgg caatatcaac acgattctta tcatcagttt cttgagggta
    12721 agggaattca agcatccatg tcacgtaagg gtaacagccc agacaatggt atgatggagt
    12781 ccttctttgg gattctgaaa tcggaaatgt tttacggtta tgagaagtcg tttcagtcgc
    12841 ttaagcaatt ggaacaagcc attgtagact atattgatta ctacaacaat aaacgaatta
    12901 aggtaaaact aaaaggactt agccctgtgc aatacagaac taaatccttc ggataaatta
    12961 attgtctaac tttttggggt cagtacagaa ctggcgtttt attttttagg atcttgatgg
    13021 gttaggttca atccccaagg gaccaaattt tcagttttat ttttgatacg agctatattg
    13081 tccttatgac gaatgataat caaactagca agtgctaaga taatagcgat gaagagagag
    13141 tcatagttac tcaggataaa accaaaaagt ggaaagagca gaaccccgat aacagccgcg
    13201 atcgatgctg tgacactaga cagtgaaatc atactgccaa gatagagagc tccaaagaag
    13261 ataatcgcaa ggtagagaca gaagataggc gcaaatccga aaatcactcc agcactggtt
    13321 gcgacagcct taccaccttt aaatcctgca aagataggga aggtatggcc gataacagcc
    13381 aaaagtccaa agatgagagg agaaacgcct tgtagatgaa aaataatcgg aagcagcgtt
    13441 gctagggttc ctttgaaaaa gtcaatcaca aaggttgcca taccagcttt cttacctaaa
    13501 atgcggaagg tgttggtcgt tccagtgtta ccagaaccat gctcgcgtag attgatttga
    13561 aagaatactt gtccaatcca gagaccagat ggaatcgaac ccagcagata ggctaggatt
    13621 aataaaacta ttgtaatcat actcctatta tatcatgaat tgggaaagaa aagcagagaa
    13681 tctctgctga aattgtcaca tcggagaaag aaaaattttg caaaatcctt ggaaaacctg
    13741 tagaatagta aagatgaacg aataggaggt tccttgtgtc aaaaaaggaa atcaatatta
    13801 acaattataa tgatgatgct attcaggtgc tagaagggtt ggatgcggtc cgaaaacgtc
    13861 cagggatgta tattggatcg accgatggcg ctggtcttca tcacctagtt tgggaaatcg
    13921 ttgataatgc agtcgatgaa gccttgtctg ggtttggtga tcgtattgat gtaactatca
    13981 ataaagacgg tagtctaacg gttcaagacc atggacgtgg gatgccgaca ggtatgcacg
    14041 ctatgggaat tccaactgtt gaggttatct ttaccattct tcatgccgga gggaaattcg
    14101 gtcaaggtgg ctataagaca tcaggtggac ttcacggagt gggttcttcc gttgttaacg
    14161 ccctttctag ctggttagaa gttgaaatta cccgtgatgg cgcagtttac aagcaacgtt
    14221 ttgaaaatgg tggaaaacct gtcacgactt tgaagaaaat cggtacagca cccaagtcta
    14281 aaacaggcac caaagttact tttatgcctg acgcgactat cttttctacg acagatttca
    14341 agtacaatac catttcagag cgccttaatg aatcagcctt tctcttgaaa aatgtgacct
    14401 tgtctttaac ggacaagcga acagatgaag cgattgagtt ccactatgag aatggagtac
    14461 aagattttgt ttcttatctc aacgaagata aggaaatctt gacgccagtt ctttactttg
    14521 aaggggaaga caatggtttt caagtggaag tagccctcca gtacaatgac ggattctcag
    14581 ataacattct atcctttgtc aataacgttc gcaccaagga cggtggaacg cacgagacag
    14641 gattcaagtc tgccattacc aaggtcatga atgactatgc acgtaaaaca ggtcttctca
    14701 aggaaaaaga taaaaacctt gaaggttcag actatcgtga gggactagcg gtcgttcttt
    14761 ctatcttagt tcctgaagaa cacttgcagt ttgaaggaca gaccaaggat aaactaggaa
    14821 gccccctagc tcgcccagtt gtggatggaa tagtggctga taagttgacc tttttcctta
    14881 tggaaaatgg ggaattagct tctaacctca tccgcaaggc tatcaaggcc cgtgatgctc
    14941 gtgaagcagc acgtaaggcg cgtgatgaga gccgaaatgg gaagaaaaac aagaaagata
    15001 agggcttgtt gtctgggaaa ttgaccccag cccaatctaa gaatcctgct aagaatgaac
    15061 tctatctagt tgagggggac tctgccggtg gttctgccaa acaaggtcgt gaccgcaagt
    15121 tccaggctat tctacctctt cgtggtaagg ttgtcaatac agccaaggcc aagatggcgg
    15181 atatcctcaa aaatgaagag attaatacca tgatttatac cattggtgcg ggtgttggag
    15241 cagacttctc tattgaagat gccaactatg ataagatcat tatcatgacc gatgcggata
    15301 ccgacggtgc ccatatccag accttgctct tgacattttt ctaccgttac atgcgtccgc
    15361 tagtcgaggc aggtcatgtc tatattgccc tcccacctct ttataagatg tccaaaggta
    15421 aaggcaagaa agaagaagtg gcctacgctt ggacggacgg agaactagaa gaactccgta
    15481 aacagttcgg taaaggcgct accctccaac gatacaaagg acttggtgag atgaatgcgg
    15541 accagctctg ggaaacaacc atgaacccag aaacacgtac cctcatccgt gtcacaattg
    15601 aagatttagc gcgcgccgaa cgccgcgtca atgttctcat gggagataag gtagaaccac
    15661 gccgtaaatg gattgaagat aatgtcaagt ttacgctaga agaagcgaca gtgttttaat
    15721 gaaagaaaat aatatgttag taaactggaa attagagtcg gatgtgaatg actatgtgaa
    15781 aaagcagttt gaaaatcttg gtttgaaaaa attgcaggat tattaatgaa gaatctgcta
    15841 tgagtgctta tctcaaagag gcgcttaagg gagcggctaa gacacaaact aagactaatt
    15901 ttggaaaacc agattttcat attgaaaaat acaaacagga tagtttggtt acttatcgta
    15961 actgaacacg ggaggaattc ccgtaaaata tcttttactg cataaaaaac tactctacat
    16021 tctttgaaag gagttgaaca cgccctagat actgtgtgaa aaagataaat tctcttgtga
    16081 gtttgcttac ttcaagaatt ttctattttc acttggtatt ttatgggctt tgtatcttat
    16141 gtctaacatt caaaacatgt ccctggagga catcatggga gagcgctttg gtcgctactc
    16201 caagtacatt attcaagacc gggctttgcc agatattcgt gatgggttga agccggttca
    16261 gcgccgtatt ctttattcta tgaataagga tagcaatact tttgacaaga gctaccgtaa
    16321 gtcggccaag tcagtcggga acatcatggg gaatttccac ccacacgggg attcttctat
    16381 ctatgatgcc atggttcgta tgtcacagaa ctggaaaaat cgtgagattc tagttgaaat
    16441 gcacggtaat aacggttcta tggacggaga tcctcctgcg gctatgcgtt atactgaggc
    16501 acgtttgtct gaaattgcag gttaccttct tcaggatatc gagaaaaata cagttccttt
    16561 tgcatggaac tttgacgata cggagaaaga accaacggtc ttgccagcag cctttccaaa
    16621 cctcttggtc aatggttcga ctgggatttc ggctggttat gccacagaca ttcctcccca
    16681 taatttagct gaggtcatag atgctgcagt ttacatgatt gaccacccaa ctgcaaagat
    16741 tgataaactc atggaattct tgcctggacc agacttccct acaggggcta ttattcaggg
    16801 tcgtgatgaa atcaagaaag cttatgaaac tgggaaaggg cgcgtggttg ttcgttccaa
    16861 gactgaaatt gaaaagctaa aaggtggtaa ggaacaaatc gttattactg agattcctta
    16921 tgaaatcaat aaggccaatc tagtcaagaa aatcgatgat gttcgtgtta ataacaaggt
    16981 agctgggatt gctgaggttc gtgatgagtc tgaccgtgat ggtcttcgta tcgctatcga
    17041 acttaagaaa gacgctaata ctgagcttgt tctcaactac ttatttaagt acaccgacct
    17101 acaaatcaac tacaacttta atatggtggc gattgacaat ttcacacctc gtcaggttgg
    17161 gattgttcca atcctgtcta gctacatcgc tcaccgtcga gaagtgattt tggcgcgttc
    17221 acgctttgac aaagaaaagg ctgagaaacg tctccatatc gtcgaaggtt tgattcgtgt
    17281 gatttcgatt ttggatgaag tcattgctct tatccgtgct tctgagaata aggcggacgc
    17341 caaggaaaac ctcaaagtta gctatgattt tacggaagaa caggctgagg ctatcgtaac
    17401 tttgcaactg taccgtttga ccaataccga tgtggttgtc ttgcaggaag aagaagcaga
    17461 gcttcgtgag aagattgcta tgctggcggc tattatcggt gatgaaagga ctatgtacaa
    17521 tctcatgaag aaagaacttc gtgaggtcaa gaagaaattt gcaactcctc gtttgagttc
    17581 tttagaagac actgcgaaag caattgagat tgatacagct agtcttatcg ctgaggaaga
    17641 tacctacgtc agcgtgacca aggcaggtta catcaagcgt accagtccac gttcctttgc
    17701 ggcttccacc ttggaagaaa ttggcaagcg tgatgatgac cgtttgattt ttgttcaatc
    17761 tgccaagaca acccagcacc tcttgatgtt cacaagtctt ggaaatgtca tctacagacc
    17821 aatccatgag ttggcagata ttcgttggaa ggacatcgga gagcatctga gccaaaccat
    17881 cacaaacttt gaaacgaatg aagaaatcct ttatgtggaa gtactggatc agtttgacga
    17941 tgcgacaacc tactttgcag tgactcgcct tggtcaaatc aaacgggtag agcgaaaaga
    18001 attcactcca tggcggacct atagatctaa gtctgtcaag tatgctaagc tcaaagacga
    18061 tacagatcag attgtagcag tggctccgat taaactagat gatgttgtct tggttagtca
    18121 aaatggttat gccctgcgtt tcaatatcga agaggttccg gttgtcggtg ctaaggcagc
    18181 aggtgtcaag gctatgaatt tgaaagaaga tgatgtcctc caatctggct ttatctgtaa
    18241 tacttcgtcc ttctacctct tgacccagcg tggaagcttg aaacgtgttt ccattgagga
    18301 aattctagca accagccgtg ccaaacgagg attacaagtc ttgcgtgagt tgaaaaacaa
    18361 accgcatcgt gtcttcttgg caggagcagt tgcagagcaa ggatttgttg gcgatttctt
    18421 cagtacggaa gtggatgtga acgaccaaac tctgcttgtc caatccaata aaggaacaat
    18481 ctatgaaagc cgattgcaag acttgaactt gtcagaacgc actagcaatg gaagcttcat
    18541 ttctgacacg atttcagatg aagaagtttt tgacgcttat cttcaggaag tagttactga
    18601 agataaataa gtgaaatgaa gaatcagttc taagagctgg tttttattgg agaaattttc
    18661 tgaaaattac aaaatatact tgctatttta gaaaaatagt gtagaatata agaaataggt
    18721 ttttagaata aggagtggaa tatgacagta acgattgatt gggaaaacct cggtttttcc
    18781 tatatgaaat taccttatcg ctatcttgct catttcaaaa atggacaatg ggatcaagga
    18841 gagcttacag aggatgcaac tttgcatatt tcagagtctt ctccaagtct tcactatgga
    18901 caacaagcat ttgaaggttt gaaagcttat cgtactaagg atggcagtgt tcaactgttc
    18961 cgtcctgatg aaaatgctaa acgtctgcaa cgtacatgtg accgtctctt gatgccacaa
    19021 gttccgacag acatgtttgt agaagcttgt aaagcagttg tccgtgcgaa tgaagaatac
    19081 gtaccaccat acggaacagg tggaacctta tatcttcgcc ctcttttgat tggtgtcgga
    19141 gatattatcg gggtaaaacc ggcagaagag tacattttca ccatctttgc tatgccagtt
    19201 ggaaattact ttaaaggtgg tttggtccca accaacttct tgattcagga tgagtacgac
    19261 cgtgcagcac caaatggtac aggtgcggct aaggttggtg gaaactatgc tgcaagtctc
    19321 ttaccaggaa aaatggccaa gtcacgtcat ttctcagatg ttatctatct ggacccatca
    19381 actcatacaa agattgaaga agtcggatca gctaacttct ttggaattac agctgataat
    19441 gaatttgtaa caccattgag tccatctatc ttgccatcta ttaccaagta ttccttgctt
    19501 tatttggcag aacatcgctt gggattaact cctattgagg gtgatgttcc aattgataat
    19561 cttgaccgtt ttgtagaggc aggtgcctgt ggtacagcag cggttatttc tccaattgga
    19621 ggtattcaac atggtgatga tttccatgta ttctatagtg aaacagaagt aggtcctgtg
    19681 acgcgtaaat tatataatga attgacgggt attcagtttg gcgatattga agcgccagaa
    19741 ggttggattg taaaagtaga ttaaaataaa ccaaaggaga ttttttatga aatagaaaaa
    19801 gtggctctta acagcaggag tggtcctgag cacgtcagct attttagtgg cttgtggaaa
    19861 aactgataaa gaagcagatg caccgacaac attttcttat gtctatgcag tagatccagc
    19921 atcattgggc tacagtatag cgactcgaac atcgaggaca gacgttattg gaaatgttat
    19981 tgatggtttg atggaaaatg ataaatacgg caatgttgct ccttctcaaa aagactatga
    20041 tttgaatagt acaggatggg ctccaagcta tcaagatcca gcgtcttact tgaatattat
    20101 ggatccaaaa tctggttctg ccatgaaaca ccttggtatt acgaaaggaa aagataagga
    20161 tgttgtagct aaacctggtt tggataaata taagaaattg ttagaagatg ctgtttctga
    20221 gaccactgac ctagagaaga gatatgaaaa atatgccaaa gctcaagctt ggtcgacaga
    20281 tagttcatta ttgatgccaa cagcttcatc tggtggttct ccagttgtaa gtaacgtagt
    20341 accattctca aaaccatact cacaagttgg tattaagggg gaaccatata tctttaaagg
    20401 aatgaaattg caaaaagata ttgttacaac aaaagaatat aacgaggttt ttaaaaaatg
    20461 gcaaaaagaa aaattggaat ccaatagcaa ataccaaaaa gaactagaaa aatacattaa
    20521 ataaggaatg gtattgatct tgataaaatt tttaaaatac tgtcattttg aatataaagg
    20581 agtttgatat ggagtggatt agattaatag gaatagcaat cattgttgtg ggttttattt
    20641 taaaatttga tacaattgca acagtagtct tagctggttt ggttacagct ttagtttcag
    20701 gtgtttctct cgttgaattt ttggagattt tgggaaaaga atttagcaat cagcgagtgc
    20761 tcacgatttt tatggttacc ttgcctcttg tggggctgtc agaaaccttt ggactcaagc
    20821 aacgatcaat cgatttgatt cgaaagatta aaggtctgac agttggaaac ttctatacag
    20881 tttatttttt tattcgagag ttagctggtt tcttttcaat tcgtctagga ggacaccctc
    20941 agtttgtcag acctttggtt caacctatgg gagaagcagc tgcagagtct caattaggta
    21001 gaaagttaac agaggttgaa gatgagacaa taaaagcgcg tgcggctgcg aatgaaaatt
    21061 ttggaaattt ctttgctcaa aatacgtttg taggtgctgg gggagtcctc ttgatagggg
    21121 gaacattaga tcagttaggc tatgaaagca attatgcagg gattgcttct acatctatta
    21181 ttgttgctgt tataacactt attgtagtgg ggatttacaa ttatttattt gataaaaaat
    21241 tgatatcaaa aaagactagg ggaggagaac aaaaatgaca gagttggcaa agcaactatt
    21301 agagttgacc tatattgtga ttggttgtca atttctccat acagcctatt gtagttataa
    21361 agataaaaca aacccagttc gacttgggac atctgcattt tggactctat tgtctattac
    21421 gtttataggt ggttcctata tgtcaaatat gagtattggt attattgtaa tcctattatc
    21481 gctgttaaca ttgtttaagc aagtccgtat cggaaccttg ccatccttag atgaaatgaa
    21541 agccaatatt gaatctaaca ggttgaaaaa taaaattttt attccagtta tgctgatggc
    21601 aatacttgcg ttggtcttag cgcaaatgat tccagaattt agcaagattt cgattagcct
    21661 tgccgccttg tttgctacaa tttctgttct tgtgattacc aatagtcacc ctaagagtct
    21721 gttatcagaa aataatcgaa tgactcagca agtttcaaca agtggtattg ttcctcaatt
    21781 attaggggct ttgggggcta tttttactgt agcaggtgtt ggtgatgtta tctctcatct
    21841 gattagcggt attgttcctt cagatagtcg ctttatagga gttttggcct atgttcttgg
    21901 aatggttcta ttcacaatga ttatgggaaa tgcttttgca gcattcaccg ttattacagc
    21961 aggtgttgga gttccctttg tatttgctct gggagctaat ccaattgtgg ctggtgctct
    22021 tgccatgaca gcaggttatt gtgggacctt attgacccca atggctgcta attttaacgc
    22081 tctaccagca gcattgatgg atatgaaaga tcagaatggc gttataaagg ctcaagcagg
    22141 tgttgctcta gtaatgattg ttattcacat attcttaatg tactttctcg cattttagta
    22201 aaggaaaata aaatgaaaat attggttaca ggttttaatc cttttggagg tgaaaagatt
    22261 aatccagctt tggaggctgt aaaattatta ccatctgaga ttaatggggc tgaagttcgc
    22321 tgggtagaaa ttccaacggt tttttataag tcgtcagaag ttttagaggc agaaatatta
    22381 cgatatcaac cagatgctgt actttgtatt ggacaagcag gcggcaggac cggcttaaca
    22441 cctgaacgag tggctattaa tcaagatgat gctcgcatac ctgataacga aggcaatcaa
    22501 ccaattgata caccgattcg tattgatgga gcatcggcct attttagtag tttacctatc
    22561 aaagcgatgg tacaagctat caaaaaacag ggacttccgg cagttgtatc caatagtgca
    22621 ggaacctttg tttgcaatca tttgatgtac caagctcttt atttagtgga taaaaaattc
    22681 cctaatatga gagcaggttt catgcatatt ccatatatga tggaacaagt agtaaataag
    22741 ccgaatactg caggaatgag tctatgtgat attgtaagag gcatagaggt agctattgaa
    22801 gctattgtag actacaaaga taaggatttg cagttagtag gcggtgagac tcactgataa
    22861 cctaaaaagg atagtcaatt atgcttgttt actaactatt agctatgcta aatcgattga
    22921 ggttgtttac ataaaactct atatcagaga agcctgatat agagtttttt cttgctagtt
    22981 ttaggatttt cttgtaaaat agaaaaagtg aagagaggta tgaaatgagc aagaaagata
    23041 aaaaaatcga aattcaagta gcggatgcca aagttaatgt tggtaaagac agttttgaag
    23101 gttatacatt gactatcggt aaaaaagtta tcggagaaat tgccgaatta gacggacaat
    23161 ttgccattat aaagaatggg aatgtcgata gtttttataa aaaattggaa aaagctgtgg
    23221 aaattttgat tgaaaattat aatttagcaa aataagtctt gtttttttga aattttcatg
    23281 atataatagt ccatgttgat tgtaggagag atagcgaaga ggctaaacgc ggcggactgt
    23341 aaatccgctc cttcgggttc gggggttcga atccctctct ctccatttca ttaatggggt
    23401 atagccaagc ggtaaggcaa gggactttga ctccctcatg cgttggttcg aatccagcta
    23461 ccccagttct taggtaataa tcaagataaa aagcaaaata tcttagggta ttttattttt
    23521 ataattgaaa gacgtgaatg atatgaacat gtccttgcgg gtgcttagga aaaaaattat
    23581 aagtatgtca agtttaagaa aaacttgatt gttggaggat tttttagatg aacgaatttg
    23641 aagatttgct aaatagcgtt agtcaagttg agactggtga tgttgttagt gctgaagtat
    23701 tgacagttga tgcgactcaa gctaacgttg caatctctgg aactggtgtt gaaggtgtct
    23761 tgactcttcg cgaattgaca aacgatcgtg atgcagatat caatgacttt gttaaagtag
    23821 gagaagtatt ggatgttctt gtacttcgtc aagtagttgg taaagatact gatacagtta
    23881 cataccttgt atctaaaaaa cgccttgaag ctcgcaaagc atgggacaaa cttgttggtc
    23941 gcgaagaaga agttgttact gttaaaggaa cgcgtgccgt taaaggtgga ctttcagtag
    24001 aatttgaagg tgttcgtgga tttatcccag cttcaatgtt ggatactcgt ttcgtacgta
    24061 acgctgagcg ttttgtaggt caagaatttg atactaaaat caaagaagtt aacgctaaag
    24121 aaaaccgctt catcctttca cgtcgtgaag ttgttgaagc agctactgca gcagctcgcg
    24181 ctgaagtatt cggtaaattg gctgttggtg atgttgtaac tggtaaagtt gctcgtatca
    24241 caagcttcgg cgctttcatc gaccttggtg gtgttgacgg attggttcac ttgactgaat
    24301 tgtcacatga acgtaacgta tcaccaaaat cagttgtaac tgttggtgaa gaaattgaag
    24361 tgaaaatcct tgatcttaac gaagaagaag gacgtgtatc actttcactt aaagcaacag
    24421 taccaggacc atgggatggc gttgagcaaa aattggctaa aggtgatgta gtagaaggaa
    24481 cagttaaacg tttgactgac ttcggtgcat ttgttgaagt attgccaggt atcgatggac
    24541 ttgttcacgt atcacaaatt tcacacaaac ggattgaaaa tccaaaagaa gctcttaaag
    24601 ttggtcaaga agttcaagtt aaagttcttg aagttaacgc agatgcagaa cgcgtatcac
    24661 tttctattaa agctcttgaa gaacgtccag cccaagaaga aggacaaaaa gaagaaaaac
    24721 gtgctgctcg tccacgtcgt ccaagacgtc aagaaaagcg tgatttcgaa cttccagaaa
    24781 cacaaacagg attttcaatg gctgatttgt ttggtgatat cgaactttaa tcaaattgaa
    24841 aattcacaaa atcctttgtt tactaaacaa gggatttttc tggctctttg tcaactgtag
    24901 tgggttgaag tcagctaagg ttgagaaagg acaaatttcg tcctttcttt tttgatgttc
    24961 agagcgataa aaatccgttt tttgaagttt tcaaagttcc gaaaaccaaa ggcattgcgt
    25021 ttgataagtt tgatgagatt attggtcgct tccaatttgg cgtttgaata gggtagttga
    25081 agggcgttga cgattttctc tttgttcttt agaaaggttt taaagacagt ctgaaaaaga
    25141 ggatgaacct gcttaagatt gtcctcaata agtccgaaaa atttctctgg ttccttatta
    25201 tagagctgat agtggtgttt caagtcttct gaatagctca aaagcttgtt taaaatctct
    25261 ttattggtta agtacatacg aaaagtagaa cgataaaatc gcttatcact cagtttacgg
    25321 ctatcctgtt gaatgagttt ccagtagcgc ttgatagcct tgtattcatg agactttcga
    25381 tgaaactgat tcatgatttg gacatgcaca cgactcatag cacggctaag atgttgtaca
    25441 atatgaaagc gatcaagaac gattttagca ttcgggagtg aaacagtctg ggagactgtt
    25501 tcagcctgag cctagaaatt tgaaagcgaa gttgtctagc taagtcatag taaggactaa
    25561 acatatccat agtaatgatt ttgacgcgac atcggacggc tctatcgtag cgaagaaagt
    25621 gatctcggat gatagcttgt gttctacctt caagaacagt gatgatattg agcttttcaa
    25681 aatcttgcgc aataaagctc atctccatct cccgattgaa acagtcactc cccggactgt
    25741 ttcaacgtcc caagacataa tctcaggcag atttctaaaa ttacactcaa agtggaagtc
    25801 attgagcttt cgaatgacag ttgaagttga gatggaaagc tgatgggcaa tatcggtcat
    25861 agaaatcttt tcaattaact tttgagcaat cttttggttg atgatacgag ggatttggtg
    25921 attcttcttg acgatagaag tttcagcgac
//
LOCUS       DAVLBE010000026        24982 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.026, whole genome shotgun sequence.
ACCESSION   DAVLBE010000026 DAVLBE010000000
VERSION     DAVLBE010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24982)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24982)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24982
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.026"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(<1..914)
                     /locus_tag="VXB91_001169"
     CDS             complement(<1..914)
                     /locus_tag="VXB91_001169"
                     /EC_number="6.3.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HEV0470630.1"
                     /translation="MSKEKVILAYSGGLDTSVAITWLKKDYDVVSVCMDVGEGKDLDF
                     IHDKALKVGAVESYVIDVKDEFATDYVLVAHQSHAYYEQKYPLVSALSRPLISKKLVE
                     IAHQIGATTIAHGCTGKGNDQVRFEVSIAALDPNLKVIAPVREWKWSREEEIYYAKKN
                     GVPVPADLDNPYSVDQNLWGRANECGILENPWNQAPEEAFGITTSPEQAPDMPEYIEI
                     EFSEGVPVSLNGEVLKLADLIQKLNEIAGKHGVGRIDHVENRLVGIKSREIYECPGAV
                     TLLTAHKEIEDLTLVREVAHFKPIIENE"
     gene            complement(931..1737)
                     /locus_tag="VXB91_001170"
     CDS             complement(931..1737)
                     /locus_tag="VXB91_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001038484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEV0470631.1"
                     /translation="MNKMKKVLMTMFGLVMLPLLFACSNNQSAGIEAIKSKGKLVVAL
                     NPDFAPFEYQKVVDGKNQIVGSDIELAKAIATELGVELELSPMSFDNVLASVQSGKAD
                     LAISGVSKTDERSKVFDFSIPYYTAKNKLIVKKSDLVTYQSVNDLAQKKVGAQKGSIQ
                     ETMAKDLLQNSSLVSLPKNGNLITDLKSGQVDAVIFEEPVAKGFVENNPDLAIADLNF
                     EKEQDDSYSVAMKKDSKELKEAVDKTIQKLKESGELDKLIEDAFKASIEK"
     gene            complement(1944..2585)
                     /locus_tag="VXB91_001171"
     CDS             complement(1944..2585)
                     /locus_tag="VXB91_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0470632.1"
                     /translation="MIELENITKTIGGKVILDRLSLRIDQGDLVAIVGKSGSGKSTLL
                     NLLGLIDGDYSGRYEIFGQTNLAVNSAKSQTIIREHISYLFQNFALIDDETVEYNLML
                     ALKYVKLSKKDKLKKVEEILERVGLSATLHQKVSELSGGEQQRIAVARAILKPSQLIL
                     ADEPTGSLDPENRDLVLKFLLEMNREGKTVIIVTHDAYVAQQCHRIIELGEGK"
     gene            complement(2582..4690)
                     /locus_tag="VXB91_001172"
     CDS             complement(2582..4690)
                     /locus_tag="VXB91_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV0470633.1"
                     /translation="MKKISHLCMLLLLLCTTFFVLNVNVTREIVRIQEMGKTTYSFDL
                     YLKDVTKPTETILQFFEEVASQDKVSIIKVDNGDEVVKSGVFDKDTFPYQEFGISSLD
                     FTTDGEGVYSNKEISNKLGTIPTFLKAKPIQLMTFQTYIKDTSRSLNGRYTITSTQEM
                     DKDRIVQKWSDFFKIDQATLLEPTYKSAVEVINRDLLLSAIVFVLAILLLVLVTVYQP
                     MMEMKRVGVQKLLGFQDRAVLADVVKGNLYLLLGGALVINLGVFFLLDYKPKDLFPML
                     WLSHFLLLQLYLFISWLTYLLIQKMTISSLLKGFSSFKFGLLFNYLMKIGTTILLTVL
                     LVGVGKSLEQENKELDYQKQWISQGNYLTLETFQLNDNLWQEQLAGSGKALDYFYRFY
                     QDLVEKTQAGYVQSSSLPVKNFVQSEQIQQYQLTDTVDVYYANRNFLKSKGFKLPDTG
                     IKKVILMPASTKGEEDKNQLLGKLIAFHSMKYEEQQKRTIEEMDVEIAYYEGDWSFFP
                     YSDKRKENLSNPIISLVNDSDMMWDEKASLSTTGLNNPIKIENTVQHQKEITELVEKL
                     SDGNYLKFSSIQAIQQEKVDSYRDAVRNFNLLFALFGLFSMMISYFLLVITFLLKRRD
                     IITKKFMGWKLVDRYRPLLVLLLLGYSLPLLVLIFFAHAFLPLLLFAGFTCLDILFVL
                     ALASRMEKRSLVELLKGGIL"
     gene            complement(4745..5038)
                     /locus_tag="VXB91_001173"
     CDS             complement(4745..5038)
                     /locus_tag="VXB91_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEV0470634.1"
                     /translation="MIGEINHEKISVASLMVCSILASTSVLAVWVDGGQWNYGVGWSG
                     NFGYSDYLHSTRSHTATVKDGNKFSKDRAEAEAWARASIFKFPPTGMEYFYGF"
     gene            5444..5764
                     /locus_tag="VXB91_001174"
     CDS             5444..5764
                     /locus_tag="VXB91_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEV0470635.1"
                     /translation="MQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMCKQICYTL
                     LEDAKNKKSYDRLAICYVRIGICTDDSKLIQKGFSLLELTEETSMLSHLKKEVEIYYQ
                     AKER"
     gene            complement(5816..6403)
                     /locus_tag="VXB91_001175"
     CDS             complement(5816..6403)
                     /locus_tag="VXB91_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEV0470636.1"
                     /translation="MKSITKKIKATLAGVAALFAVFAPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVGQELVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVAETPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNG
                     DYSAENQERVADAYVAGRYGSWTAAKNFWLNNGWY"
     gene            6645..7316
                     /gene="sdaAB"
                     /locus_tag="VXB91_001176"
     CDS             6645..7316
                     /gene="sdaAB"
                     /locus_tag="VXB91_001176"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HEV0470637.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            7325..8197
                     /gene="sdaAA"
                     /locus_tag="VXB91_001177"
     CDS             7325..8197
                     /gene="sdaAA"
                     /locus_tag="VXB91_001177"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HEV0470638.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIENGKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            8219..8851
                     /locus_tag="VXB91_001178"
     CDS             8219..8851
                     /locus_tag="VXB91_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV0470639.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAMQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKNTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIII
                     GDTKFDMLGARETGIQKLAVTWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
     gene            8877..8975
                     /locus_tag="VXB91_001179"
                     /pseudo
     CDS             8877..8975
                     /locus_tag="VXB91_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(9157..11007)
                     /locus_tag="VXB91_001180"
     CDS             complement(9157..11007)
                     /locus_tag="VXB91_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEV0470640.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMIGFWGLNASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVAKAVDEAKVSKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE"
     gene            complement(11049..12206)
                     /locus_tag="VXB91_001181"
     CDS             complement(11049..12206)
                     /locus_tag="VXB91_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV0470641.1"
                     /translation="MSSKVSGFQDKNGKVLKIMIEWWKEKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKENVEILFINAMSTDGTTAIIQQFIKEDTEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGDLILKIDAHSKVTESFVMNNVAIIQQGEFVCGGPRP
                     TIVEGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREHGYKIRYSPSILSYQYIRPTFKKMLHQKYSNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLTLLTLLKHKNGF
                     LIVMPFLLFSIHFAYGLGTIVGLIRGFKWKKEYKRTIIYLDKISQINKNML"
     gene            12264..13430
                     /locus_tag="VXB91_001182"
     CDS             12264..13430
                     /locus_tag="VXB91_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HEV0470642.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTRLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     VGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGL
                     ILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFY
                     TVMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVS
                     LAGVVGISMLFFPINNFIYWLTIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGL
                     SQTGGYILAAFGPTLFGYSFDLFHSWVPAVAALLLIYILMTVALFTVDRADKIL"
     gene            13569..13895
                     /locus_tag="VXB91_001183"
     CDS             13569..13895
                     /locus_tag="VXB91_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEV0470643.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWTLYTDTINGIIEGS
                     IRHDKN"
     gene            13882..14475
                     /locus_tag="VXB91_001184"
     CDS             13882..14475
                     /locus_tag="VXB91_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HEV0470644.1"
                     /translation="MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEEL
                     IASLGTPKEAAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTVLAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYVTRFFGLLIVRLVQFVLKKGKRGNQHA"
     gene            14468..15379
                     /locus_tag="VXB91_001185"
     CDS             14468..15379
                     /locus_tag="VXB91_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HEV0470645.1"
                     /translation="MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPVY
                     DSRTEKLTFGKEVENLEITLHQHTLTITDSFDDQIHISYHPSLSAHHDLITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILRLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTENHFHAEN
                     IQVHGKVELTAKDYLRIILDQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            15442..16506
                     /locus_tag="VXB91_001186"
     CDS             15442..16506
                     /locus_tag="VXB91_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0470646.1"
                     /translation="MKQEWFESNNFVKTTSKNKPEEQAQEVADKAEETIADFDTPIEK
                     NTQLEEEVSQAEVELESQQEEKIETPEGGEARTEIEEKKASNSTEEEPDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLESPYIPDQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKLETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIISILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
     gene            complement(16578..17438)
                     /locus_tag="VXB91_001187"
     CDS             complement(16578..17438)
                     /locus_tag="VXB91_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 domain-containing protein"
                     /protein_id="HEV0470647.1"
                     /translation="MAKTFFIPNKQSILGEQEILNAKSILALLDGLESHSYDVVYLRQ
                     PLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDLPDLLTKTDWQIIKSFLDALLAYT
                     GTDIEGLDGFDFEAYFQASIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLA
                     QFEARVRAVQETDAYFARVSFYQDGEGKVHGVYHLAQGVKTVLPREPFVPAAYIEQLV
                     DKEVQWEIDLVQITGDDSKPEDYESIARLDYAKFLEVLPPSFYHQLDANQIEIQPILV
                     QDFKTLAQEK"
     gene            complement(17560..18546)
                     /locus_tag="VXB91_001188"
     CDS             complement(17560..18546)
                     /locus_tag="VXB91_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HEV0470648.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEELWFKIDEENEQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            complement(18818..20293)
                     /locus_tag="VXB91_001189"
     CDS             complement(18818..20293)
                     /locus_tag="VXB91_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3502 domain-containing protein"
                     /protein_id="HEV0470649.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            complement(20551..21474)
                     /locus_tag="VXB91_001190"
     CDS             complement(20551..21474)
                     /locus_tag="VXB91_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV0470650.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            complement(21488..22417)
                     /locus_tag="VXB91_001191"
     CDS             complement(21488..22417)
                     /locus_tag="VXB91_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0470651.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGALWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            complement(22736..22957)
                     /locus_tag="VXB91_001192"
     CDS             complement(22736..22957)
                     /locus_tag="VXB91_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0470652.1"
                     /translation="MSLQIKLKKLAKELSKLLKDSNLETVDKDVLENSQKELQKAVLF
                     LADEKGSEHTAAELIDNLKEVIAKLKANA"
     gene            complement(22911..23171)
                     /locus_tag="VXB91_001193"
     CDS             complement(22911..23171)
                     /locus_tag="VXB91_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0470653.1"
                     /translation="MTGVSNPTTDSARLVLAEAKKALTDDSLTEQGLRDILQTVKDAI
                     ASLESIKESQSATKDGGQTAGKETAGEDESANQTQEISQGIK"
     gene            complement(23444..23767)
                     /gene="tnpB"
                     /locus_tag="VXB91_001194"
     CDS             complement(23444..23767)
                     /gene="tnpB"
                     /locus_tag="VXB91_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEV0470654.1"
                     /translation="MMIQLSDLGQVHLVCGKTDMIQGIDSLAYLVKTHFELDPFSGQV
                     FLFCGGRKDRFKALYWDGQGFWILYKRFENGKLTWPSTEKDVKALAPEQVDWLMKGFS
                     ITPQI"
     gene            complement(24028..24327)
                     /locus_tag="VXB91_001195"
     CDS             complement(24028..24327)
                     /locus_tag="VXB91_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HEV0470655.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKASVDEANIKTLYSEKLIGISIPIK"
     gene            complement(24492..24899)
                     /locus_tag="VXB91_001196"
     CDS             complement(24492..24899)
                     /locus_tag="VXB91_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013315450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV0470656.1"
                     /translation="MARYGVYAVIPNPEQKQIVLVQEPNGAWFLPCGEIEAGENHQEA
                     LKRELIEELGFTAEIGTYYGQADEYFYSRHRDTYYYNPAYLYEATPFKEVQKPLENFN
                     HIAWFPIDEAIKNLKRGSHKWAIESWKKQHKID"
BASE COUNT         7462 a         5350 c         4582 g         7588 t
ORIGIN      
        1 aattcatttt ctatgattgg tttaaaatga gccacttctc tcacaagcgt caagtcctca
       61 atttccttat gagctgtcag cagggtcact gcacctggac actcatagat ttctcttgat
      121 ttaatcccaa ccaagcgatt ttccacgtgg tcaatccgtc caaccccatg ttttccagct
      181 atttcattga gtttttgaat caaatctgcc aattttaaca cttctccatt gagggaaact
      241 ggaacacctt cactaaactc aatctcaatg tattctggca tatctggagc ttgctctgga
      301 gaagttgtga tgccaaaggc ttcttctgga gcctgattcc atggattttc caaaatacca
      361 cactcattgg cacgtcccca aagattttgg tcgacagagt agggattgtc aaggtcagca
      421 ggaacaggca ccccattttt cttggcataa taaatttctt cctcccgaga ccatttccat
      481 tcacgaactg gagcaatcac ttttaaattg ggatccaagg ctgcaatcga tacttcaaaa
      541 cgtacttggt cattcccctt accggtacaa ccatgagcaa ttgtagtcgc tcctatctga
      601 tgcgctattt caaccaattt tttagaaatc agagggcggc tcaaggcaga taccaaggga
      661 tacttttgtt cataataggc atgtgactga tgagccacta gcacataatc tgtagcaaat
      721 tcgtccttaa catcaatgac ataagattct actgccccaa ccttaagagc cttatcatgg
      781 atgaaatcta agtctttccc ttcacccaca tccatacaaa ctgaaacaac atcatagtct
      841 ttctttaacc aggtaatagc aactgatgtg tccaaaccgc cagaataggc caaaattact
      901 ttttctttac tcatgttctt ttccttcttt ctatttttca atggatgctt taaaggcatc
      961 ctcaatgagt ttgtctaatt ccccagactc cttcaacttt tgaatagttt tatcgactgc
     1021 ctctttcaat tccttactat cttttttcat ggctaccgag taggaatcat cttgctcttt
     1081 ttcaaaattg aggtctgcga ttgctaaatc aggattattt tccacaaagc ccttggcaac
     1141 tggttcttca aagataacgg catccacttg tcctgatttt aaatctgtga ttaaattccc
     1201 atttttaggc agagatacga gggaagaatt ttgtagcaaa tctttcgcca tcgtctcttg
     1261 aatcgaacct ttctgggctc cgaccttctt ctgcgctaag tcgttgacag actgataagt
     1321 gactaaatca gattttttga caatgagttt attttttgca gtatagtagg gaatggaaaa
     1381 gtcaaacacc ttgctccgtt catctgtctt agaaacacct gatatggcaa gatcagcttt
     1441 tcctgattga acactagcca gtacattgtc aaaactcatg ggagatagtt ccaattcgac
     1501 acctagttct gttgcgatag ccttggctaa ttcgatatct gaacccacaa tctgattttt
     1561 cccatcaacc actttttggt attcaaatgg agcaaaatct ggattgaggg ctacaaccaa
     1621 ttttcctttg gacttgatgg cttcaattcc agccgattga ttgttactac aagcaaatag
     1681 tagggggagc atcactaaac caaacatcgt catcaacacc ttcttcatct tattcataac
     1741 aaagcctcct ttatgtttat tccttttgtt tgtataaata atacacctat cttcatcctt
     1801 tgtcaagcct aaattgtaat ttttttcaat ttaaaacaga aaaacctagg aaaattacat
     1861 aaaaatgtca ttcctaggcg tatttatgct attcctctct ggaaaatatg agtattcagt
     1921 cagtcaaaag aagctgaacg aactcatttt ccctcgccca attcaataat ccgatgacat
     1981 tgttgggcta cataagcatc gtgggtcaca ataatgactg ttttcccttc tcgattcatc
     2041 tctaagagaa acttcaagac caaatctcta ttttcaggat ccagcgaacc tgtaggttca
     2101 tcggctaaaa tcagctggct gggttttaag atggctctag caactgcaat tcgttgttgt
     2161 tcgccaccag acaactcgga gaccttttga tgcaaagtag ctgacaaacc tactctctct
     2221 aaaatctctt ccaccttttt gagcttatct ttcttagaca attttacata tttcagcgcc
     2281 agcataagat tgtactcgac cgtttcatca tcaatcaggg caaaattttg aaacagataa
     2341 gagatatgtt cacggattat tgtttgcgac ttagcagaat tgaccgctag atttgtctga
     2401 ccaaaaatct cataccgtcc gctataatca ccatctatca aacccaataa atttaacaag
     2461 gtcgacttcc cactaccact cttaccaaca atggcaacca aatccccctg atcaatcctg
     2521 agagacaagc gatccaaaat cactttcccc ccaatggttt tggtaatatt ttccaactca
     2581 atcataagat gccccctttc aataactcta ctagacttct tttctccatc ctagaagcca
     2641 aggctagcac aaatagtata tccaaacatg taaagcctgc aaacagcagg agtggcaaga
     2701 acgcatgggc aaagaaaatc aagactagaa gagggagact atagcccagc aagagcagaa
     2761 cgaggagagg acggtagcga tcgaccagtt tccaccccat aaacttcttg gtaataatat
     2821 ccctgcgctt caataagaaa gttattacta gtaagaagta ggaaatcatc atgctaaaga
     2881 gaccaaacaa agcaaagagt aggttaaaat tccgaacagc atctcgataa gaatccactt
     2941 tctcttgttg aatggcttga atagatgaaa attttaaata atttccatct gacaatttct
     3001 caactaactc tgtaatctct ttttgatgtt gaaccgtatt ttcaatttta atcggattat
     3061 ttaagccagt tgttgacagg gaggctttct catcccacat catatcagaa tcattgacca
     3121 agctaataat tggattggag agattttcct ttcgcttatc actatatggg aaaaatgacc
     3181 aatctccttc ataataggca atctcgacat ccatctcctc tatcgttcgt ttttgctgct
     3241 cttcatactt catcgaatga aaggcaatta acttccccaa gagctgattt ttatcttctt
     3301 cacctttcgt acttgctggc atcaaaataa cttttttaat accagtatct ggtagcttga
     3361 atcccttgct ctttagaaaa ttgcgattgg catagtaaac atccaccgta tctgttaact
     3421 gatattgctg aatctgttct gattggacaa aattttttac aggaagactg ctactctgca
     3481 catagcccgc ctgcgttttt tctactaaat cctgataaaa tcgatagaaa taatccaatg
     3541 ccttccctga gcctgccaac tgctcttgcc acaagttgtc attgagttgg aaagtttcta
     3601 aggtcagata atttccttgg ctgatccact gtttctggta atccaactct ttgttttctt
     3661 gctccaaact ttttcctacc ccaactagca agactgtcag taaaatggta gttccaattt
     3721 tcatcaaata attaaagagt agaccaaatt tgaaagatga aaaacctttc agcagagagc
     3781 tgattgtcat tttttggatt aagaggtaag tcaaccaact gataaagaga taaagctgca
     3841 acagcaaaaa atgagacaac cacagcatag gaaacaaatc ttttggctta taatcaagca
     3901 agaaaaacac gcctagattg atcacaagag ccccacctag gaggaggtaa aggttgcctt
     3961 ttacaacatc agctaaaaca gccctatctt gaaaaccaag taatttttgt accccaactc
     4021 gtttcatctc catcatcggt tgatacactg tcactaacac aagaagcaaa atagccaaga
     4081 caaaaacaat ggcagataaa agcaaatctc gatttatgac ttccactgca cttttgtagg
     4141 tcggctctag caaggtagcc tggtctatct tgaaaaaatc gctccatttc tgtacaatcc
     4201 tatccttgtc catctcttgt gtagaagtta tcgtatagcg accatttaaa ctacgagatg
     4261 tatccttgat ataggtttga aaagtcataa gctgaatagg tttggctttt agaaaggtcg
     4321 gaatcgtacc aagtttattg gaaatttctt tattactata gactccttca ccatctgtgg
     4381 taaaatcaag agaagaaatc ccaaactctt ggtaggggaa ggtatcttta tcaaaaacac
     4441 cagacttgac cacctcatcg ccattatcta ctttgataat agagaccttg tcttggcttg
     4501 caacctcttc aaaaaactgg agaatcgttt ctgtcggttt agtgacatct ttcaagtaca
     4561 agtcaaatga ataagttgtc ttgcccatct cctgaatccg cactatttct cgtgtaacat
     4621 ttacattcag gacaaaaaac gtagtacaca gcaagagcag gagcatacaa agatgactga
     4681 tttttttcat agagatacct cccgtgaaga aactccctct ccaaaagggg agggagaatt
     4741 ttaattaaaa tccatagaaa tattccattc ccgttggtgg gaatttgaag attgaagccc
     4801 gagcccacgc ctcagcttct gcacgatcct tagagaattt atttccatct ttaacagttg
     4861 ctgtatgaga gcgagtagaa tgtaaataat cagaataacc aaaatttcct gaccatccta
     4921 ctccatagtt ccattgacca ccatcaaccc atactgccaa aacacttgta gaagcaagta
     4981 tactacatac cattaaagat gcaacactaa ttttctcatg atttatttct cctattatcg
     5041 agagctattc cgtagaaaca gctatagtaa tttatcaaca agtatcgtag tccattggac
     5101 tcaccttcct tctatctcat ttcattttta aacaacgaac ttactcttaa ctaggagaat
     5161 agttctcttc tgtatcaggt ctttgaacaa ccagagtagt attaatcaca ctctaactat
     5221 tactcaagaa tcagcccaat aaacaatatg gatagcgctt tcaaattttt aaactctatc
     5281 ccatcctttt atctatatta tgagcgaaaa tataataact gtcaagtaat cgaagtgaat
     5341 tttataaaaa aaattacaag ccaaatttgc aaagtttaca ataagccgct agggcaatcg
     5401 tctatcagaa tgtccgttta tttgtcaata atccgagaaa atcttgcaac gcttagaagt
     5461 ctataaaaac tatcaacatt tatatgactt gcgaatagca atcctgctca acctttccac
     5521 actctatcta tacaatcaag ataaaaacat gtgtaagcaa atctgctata ctttactgga
     5581 ggacgccaag aataagaaaa gctacgatag gctggctatc tgctatgtcc gtattgggat
     5641 ttgtacagac gattctaaac ttatccaaaa agggttctcc cttctggagc taaccgagga
     5701 aacttctatg ctgtctcatc tcaaaaaaga agtagagatc tattaccaag cgaaggaaag
     5761 ataaaaaagc cgagggattt cctcgactct ttacatatta tttgttcgtt agttcttaat
     5821 accagccgtt gttaagccag aagtttttag cagctgtcca tgaaccgtaa cgtcctgcaa
     5881 cgtaggcatc tgctacacgt tcttggtttt cagctgagta gtcaccgttc aggtatgaat
     5941 ctgttaattg gtaacgtccg atataacgtc catttgtagc tgtatagcta ccacctgatt
     6001 ctttttgagc aatccattct ttggcttctg cttcagatcc gcttacagtt gaaacaactg
     6061 tttcacttac tactggagtt tctgctactg gagctgaaac agtttcatct tgagcggctg
     6121 gtgccgcata agtagctggc gctggtgttg caacaggcgc tacagggcca tcgataacca
     6181 actcttgacc aacataaatc aaatgaatgt tatcaatgtg gttgttttct gccaattttt
     6241 caactgttgt gttgtgagtt tcagcgattt ctgaaagtgt atcaccttct ttaacagtgt
     6301 aagttgatga ttcttgagca gatacaaatg atggagcaaa tactgcaaac aaggcagcta
     6361 ctcctgcaag agttgcttta atctttttag ttattgattt catattcgaa aattctcctt
     6421 ctttctatag ttctatcata ccctttaaat attaccgttt cttgacactt ttatgtagaa
     6481 atattacaaa attatttttt atttccctaa ataaggtgtt ttttgtcata aaagatacta
     6541 tttttatgct atttgaggta ttagaaaggt tttcatccac aattaaagcc aagcccctca
     6601 ttctttgata taatagagat aagaattttt ataaggggaa actgatgaaa tcacttcgtt
     6661 ttcaatctgt ctttgatatc atcggaccag ttatgattgg cccatctagt agccatactg
     6721 ctggtgctgt tcgtattggg aagattgtct cttccatttt tgatgatact ccgacagaag
     6781 ttgaattcca actttttaac tcatttgcca agacctatcg tggtcacgga acagacctag
     6841 cccttgttgc aggtattttg ggaatggata cagatgatcc tgaaattcca aatagtctgg
     6901 aaattgccca caagcgtggt atcaagattg tctggaccat tcagaaagac agcaatgccc
     6961 ctcaccctaa caccactaaa attactgtta aaaatgccca caagaccatc agcgtgactg
     7021 gtatttctat cggtggagga aatattcagg taaccgaact caatggtttt gccgtctctc
     7081 tcaatatgaa tacaccgact atcatcatcg ttcatcaaga tattccaggt atgattgccc
     7141 ttgttacaga ggcgctttcc cgctatggta tcaatatcgc ccagatgaat gtcactcgtg
     7201 aaaaagctgg tgaaaaagcc attatgatta tcgaagttga cagtcgcaac tgtgatgagg
     7261 ctatcgaaga aattcgaaaa atccctcatc tccacaatgt caatttcttt aaataggagg
     7321 aagcatgttt tattctatca aagaattggt cgagcaagca gatctggact ttcaaggaaa
     7381 tgtcgcagaa ctcatgatta caacagagtt tgaattgacc ggtcgcgaac gtgaagaagt
     7441 cttccttctc atggaacgca atctggaagt tatgaaagcc tctgtccaac ttggcctcaa
     7501 tgaaaataaa tctcgtagtg gcctgacagg tggagatgct gccaaattgg atcactacat
     7561 cgaaaacgga aaaactttat cagattacac gattctctct gctgcccgaa atgctatcgc
     7621 agtcaatgaa cacaatgcta aaatgggctt ggtctgcgct actcctaccg caggaagtgc
     7681 cggttgtctc ccttccgttc tcactgctgc tattgaaaaa ttagacctca gccacgagca
     7741 acaattggat ttcctctttg ctgctggtgc ctttggacta gtcatcgcaa acaatgcctc
     7801 catctcaggt gctgagggtg ggtgtcaagc tgaagttggt tcagcctctg ctatgagtgc
     7861 tgccgccttg actctggctg caggtggaac accttatcag gccagtcaag ctattgcctt
     7921 tgtcattaaa aatatgctag gcctcatctg tgaccctgtt gcaggtttgg tcgaagttcc
     7981 ctgtgtcaaa cgtaatgcca tgggagctag ctttgctttc atcgcagcag acatggcctt
     8041 ggcaggtata gaatctaaaa tccctgtgga tgaagtgatc gatgccatgt accaagtagg
     8101 agcaagcatg ccaactgcct ttcgtgaaac agctgaaggt ggactcgcta ccacccctac
     8161 tggtcgtcgc ctccaaaaag aaattttcgg agaataagct tatcaaatag gagaaaccat
     8221 gacctctatc acagcgattt ttttcgattt ggatggaacc ctcgttgata gttctatcgg
     8281 gattcacaat gcctttacct atacctttaa agagctgggg gtgcctagcc ctgatgccaa
     8341 aactattcgt ggttttatgg gaccacctct cgaaagtagt tttgcgacct gcctgtccaa
     8401 agaccaaatt tctgaagcca tgcagatata tcgttcttac tataaggcaa aaggcatcta
     8461 tgaagctcaa ctctttcctc agattataga cttgcttgag gagttatcga gcagttatcc
     8521 actctacatc accacgacaa agaatacatc tactgctcaa gacatggcca aaaacttgga
     8581 aatccatcat ttctttgatg gcatttatgg ttctagccct gaagcacccc ataaggcaga
     8641 tgtcattcac caagccttac agacacatca actagcacca gaacaagcca tcatcatcgg
     8701 agataccaag tttgatatgc tgggagctcg agaaacaggt attcagaaat tggccgtcac
     8761 ttggggattt ggagagcaag cagatctact aaactatcaa cctgattata tcgctcacaa
     8821 acccttagaa gttttggcgt attttcaata gcatagactg ggcgacaact ctatttcaga
     8881 agaaaatgaa gtaatactca atgaaaatca aagagcaaac taggaaacta gctgcgggct
     8941 gctcaaaaca ctgttttaag gttgtagatg gaactgacga agtcagctca aaacactgtt
     9001 ttgaggttgt ggatagaact gacgaagtca gtaacatata catacggcaa ggcgacgttg
     9061 acgtggtttg aagagatttt cgaagagtat aagtctctac ataataaaac gcatattacc
     9121 aaggttgtgt aacttgatac tatgcgtttt tcttttttat tcaatgtggg ttgtttgatt
     9181 agcaaaggcg ataatagctt gcttcaactc atctccactg agagtgcgga actctccaat
     9241 cttttgattg atggattcta aaggcatgac attaacctta ccaacgaaaa tcttatccat
     9301 aacttgatta tcaacgagtt cggttgatac caagagttct tcgtagagtt tttcacctgg
     9361 gcggattcca acttcaacga ttggaatttc actttcagtg tggccactta gaagcaccat
     9421 cttcttggcc aagtcataaa tcttgactgg tttgcccata tcaaggataa agacttcccc
     9481 atctttggca taagcaccag catggataac cagacggcta gcttctggaa tggtcataaa
     9541 gtaacgggtc atgcggaagt ctgtcaccgt tacaggccca ccttcagcaa tctgacgttc
     9601 aaagactgga atgacactac cacggctacc aagaacattc ccaaaacgaa ctgcacagta
     9661 ggttgattgg ctacgttggt taaagccagt gacaatcaac tccgccacgc gcttggttgc
     9721 tcccataaca tttggtggat tgactgcctt atctgtcgaa atcataacca tcttagacac
     9781 tttagcttca tcaacagcct tagcaacatt gtaagttcca cggatattgt ttttgaaggc
     9841 ttcttttgga ttgcgctcca tcataggaac atgcttgtgg gctgccgcat gataaacaat
     9901 agcaggtttg tactgctcaa agacttgcaa caaacgatca tagtcttgaa tgtccgcaat
     9961 cacaggtaca taatcaatcc cttggaactt acgaatcaat tcatgataaa caaggtagat
    10021 tgagttttcc ccatgaccga gtaagacaat gcgttcagga ttgaagcgac taacttgacg
    10081 acagatttca gaaccgattg aacctccagc tcctgtgact aagatggtct tacctgtcag
    10141 ttctgcaccc agacgcgatt cgtcaagacg gatttcctga cgacccaaaa ggtccgtaat
    10201 atcaattttt tggaagccag tacctgcttg gtgaaggccc tgaacaacag tttcaacctt
    10261 aggcatcttg taacatttga cacccagctt attacacatc tgcaagatac gctcatattc
    10321 tgacggatcc agcgacggaa tcgcaacgat gacacgctcg atttgatggc gtttggctaa
    10381 ttcaggcaga ttgtcataag agcccaaaac aggaatacca ccaagttttt gacccttttt
    10441 cttagaatcc ttatccaaaa taccgaccag ttctaattca ctggttggat gttggtaact
    10501 atccataaag agagccccac catcaccggc accaatcaag aaggtccgac ggtgttctcc
    10561 atcaccacta ccttttttgc gtctggagta gattaactgc caagtaatcc gtggcaataa
    10621 aatcaagaag gtactcaaca agataaagag aatgatgaaa cggatggaga agagtggcaa
    10681 gaaggcataa cagatactat atgacaagac actgctagca gtcacaccaa aaaagatttt
    10741 catgaaatcc gtaatcttgc tgtaacgact aatgctcgcg ttcaaccccc aaaaaccaat
    10801 catcaattga tagaacaaga aggccaaact cgtatagata atgtagtcaa caggtgctgg
    10861 attaatcagc ccataaaata aaatataaga tacaattatg gaaaccacca tactgaaaat
    10921 atcaaatatt ccccagaaaa cctgcttttg ttgtttattt aaaatttcca ccagatcaat
    10981 cacataatct gttagttttt tattcataga aatctactcc tccttaaaag agttttacta
    11041 tattgttatt atagcatatt tttatttatt tggcttattt tatccaaata aattattgtt
    11101 ctcttgtact ccttcttcca tttaaatcct ctaattaaac ctacaatcgt cccaaggcca
    11161 taagcaaagt gaatggaaaa taaaagaaag ggcatcacaa ttagaaatcc atttttatgt
    11221 tttaataaag tcagcaaagt gagtaatgac aaaagtagaa aataggcacc taatagtaaa
    11281 gttatgaata cgaatgtgat cggtaacaat gctagactaa acacaagact caaaacaaat
    11341 aaacaaggaa catagtgaaa taatgataaa cacttaaact gaacatgact tgtcaagcca
    11401 atccacaaac catttgaata cttttgatgc agcattttct tgaatgttgg tcgaatatac
    11461 tgataagata gaatacttgg gctatagcgg attttataac catgttctcg aattctataa
    11521 tgaatatcat tatcttcagt tcggccaagt tgctcattta ctaaaccaac cttctggaaa
    11581 acctctcgtt tatacatccc atgaaaaata gaagaaacat atctatcctc ggaactattt
    11641 cgataattgg caatgctact gccaaacata ttttcctcaa caagatgcaa ggtctctgcc
    11701 cattttcctt ttccttcgac aatcgtcggt ctaggccccc cacagacaaa ttcaccttgt
    11761 tgaataatag ccacattgtt cattacaaaa ctctcagtaa cttttgaatg agcatcaatt
    11821 tttaaaataa ggtcccctac agaatgttta actcccaggt taaaaccact agcttgattt
    11881 ttcttaggat tgttatacaa tctaattgag ttaaactctg tatcttcctt tataaattgc
    11941 tgaatgatag ctgtggtccc atctgtggac atagcattta taaatagaat ttcaacattc
    12001 tctttaggat aggtttgatt ttttaagtct tcaattagac caggcagata tttttcttca
    12061 ttgtatgcac tgattacaat ggatacgaga agactttcaa cattttgagt cactactact
    12121 ctcctgaatt tttccttcca ccattctatc ataattttca agactttccc atttttatct
    12181 tgaaagccag aaaccttact tgacattata gtgaaaaagc cttaaaataa gctgttatta
    12241 aaatcagcta gaagaggtat tatatgaaaa agcaatcact cttttttgtt ccaggtatta
    12301 tcctgattgg tgtttccttg cgaactcctt ttactgtttt acccattatt ttgggaaata
    12361 tttcgcaagg tctggaggta gaagttagtt cgcttggtgt cttgaccagc ctgcctctcc
    12421 ttatgtttac cctcttttca ccattttcta cccgactggc tcagaaaatc ggcttggagc
    12481 atctcttcac ctacagcctc ttcttcttga ccatcggctc actcattcga ctaatcaatc
    12541 tgcccctgct ctatctagga accttgatgg ttggggcaag tgtcgcagtc atcaatgtcc
    12601 tgcttcctag tcttatccaa gccaatcaac caaagaaaat tggttttctg accaccttat
    12661 atgtaacgtc tatggggatt gcaacggctc tggcttccta tctagctgtg cccattacac
    12721 aagccagttc ttggaaagga cttatcctcc tcctcacgtt actctgtcta gcaacttttt
    12781 tggtctggct cccaaatcac cgctataatc atagactagc tccacaaacc aaacaaaaaa
    12841 gtcaaataaa ggtcatgcgt aataaacagg tttgggcaat tattatcttt tcaggttttc
    12901 aatccttgat cttttacacc gtcatgacct ggttacctac catgtctatc catgcaggtc
    12961 tatccagtca cgaagctggc ttgctgactt ctatcttatc tctgattagc attccttttt
    13021 caatgaccat cccaagcctg acaaccagtt tatctactcg caaccgtcag ctcatgctca
    13081 ctctggtttc actagctggt gtggtcggca tttccatgct ctttttccca atcaataatt
    13141 tcatttactg gcttaccatc catctcctca tcggaaccgc aaccagcgcc ctcttccctt
    13201 atctcatggt caacttttca ctcaagacaa gcgcccctga aaagacagcc caattgtccg
    13261 gcctatctca aacaggaggc tatatcctag cagcctttgg gccaaccctc tttggttaca
    13321 gttttgacct gttccactct tgggtaccag ctgtagctgc cctcttgctc atctatatcc
    13381 tgatgactgt ggccctcttt acagtggaca gagcggataa gatcctttaa acttctagtt
    13441 ttagctagaa gttttttata tataaaaatt ttacacattt ctcttgacag ggctttcttt
    13501 tagatgtaca atgtatgtgt agaaaaatta tatataaaaa tcttacacat tagaaaagga
    13561 ggtttcccat gtactttcca acatcctctg ccttgattga atttctcatc ttggctgtac
    13621 tggagcaggg tgattcttat ggttatgaga ttagccaaac cattaagctg atcgctaata
    13681 tcaaagaatc cacactctat cccattctca aaaaattgga aggcaatagc tttctgacaa
    13741 cctattctag agagttccaa ggtcgcatgc gcaaatacta ctccttgaca aacggtggta
    13801 tagagcagct cttgacccta aaagatgaat ggacactcta tacagacacc atcaatggca
    13861 tcatagaagg gagtatccgc catgacaaga actgaatacc tgactcagct agaactctat
    13921 ctcaagaaac tacctgaagc tgaccgtatc gaagccatgg actatttcag agagctcttt
    13981 gacgatgctg gagtcgaagg agaagaagaa ctcatcgcta gtttgggaac tcccaaagaa
    14041 gcggcccacg aagttctatc caatcttctc gataaaaaaa tcaatgaagc acccgctcaa
    14101 aaaaataacc gacaaatttt acatatcgcc ttgttagccc tccttgcagc acctatcggc
    14161 attcctctgg gaatcgccat cctcgtgacc ctgttcgcaa tccttgtagc cgctttgact
    14221 gtcattctgg ctttctttgc agtttccata ctgggtatca tcggcggatt cctattttta
    14281 gttgaaagtt tcactgtcct cgcccaagcc aaatcagcct ttatcttgat ttttggttct
    14341 ggtttactgg ctatcggtgc ttcttcgcta gttttacttg gcatttccta tgtaactcgc
    14401 ttcttcggtc tactcattgt tcgtctggta caatttgttc ttaaaaaagg aaagagaggt
    14461 aaccagcatg cgtaaatgga caaaaggatt tctcatcttt ggtgtggtga ctaccgttat
    14521 cggctttatc ctgctttttg taggtatcca atctgacggg attaagagcc tactttccat
    14581 gtccaaagaa cctgtctatg atagccgtac ggaaaagcta acctttggca aggaagtcga
    14641 aaacctagaa attactctcc accaacacac gctcaccatc acagactctt tcgatgatca
    14701 aatccacatt tcttaccatc catctctttc tgctcaccat gatcttatca ccaatcagaa
    14761 cgatagaact ctgagtctca ctgataagaa actgtctgaa actccgtttc tctcttctgg
    14821 aattggtggg attcttcata tcgcaagtag ctactctagt cgttttgaag aagttattct
    14881 ccgactacca aaagggagaa ctctaaaagg gatcaacatc tcagccaatc gcggacaaac
    14941 caccatcata aatgctagcc ttgaaaatgc gaccctcaat acaaacagct atatcctccg
    15001 aattgaagga agtcgtatca aaaacagtaa actcacaaca cccaatatcg ttaatatctt
    15061 tgatacagtt cttacagata gtcagctaga gtcaacagag aatcacttcc acgctgaaaa
    15121 tatccaagtc catggtaagg ttgaactgac tgccaaagat tatctcagaa tcatcctaga
    15181 ccagaaagaa agccaacgaa ttaactggga catctcaagc aactatggtt ctatcttcca
    15241 attcacaaga gaaaagcctg aatcaagagg tacggaatta agcaaccctt acaaaactga
    15301 aaaaaccgat gtcaaggatc aactcattgc gagatctgat gataatattg atctaatatc
    15361 cacaccaagc agacgttgac aaaaacgctt acatctgcta ctatggaagc atatttatct
    15421 aactaaaaag gaggttctac catgaaacaa gaatggtttg aaagtaataa ttttgtaaaa
    15481 acaacaagca agaacaagcc tgaagagcaa gctcaagagg ttgcagacaa ggctgaagaa
    15541 acgatagccg atttcgatac accaattgaa aaaaatactc agttagagga ggaagtctct
    15601 caagctgaag tcgaactgga aagccagcaa gaagagaaaa ttgaaactcc tgaaggcggt
    15661 gaagcgagaa cagaaataga agaaaagaag gcatctaatt ctactgaaga agagccagac
    15721 ctttctaaag aaacagaaaa agtcactata gctgaagaga gccaagaagc tcttcctcag
    15781 caaaaagcaa ccacgaaaga gccacttctt atcagtaaat ctttagaaag tccttatatc
    15841 cccgaccaag ctccaaaatc tagggataaa tggaaagagc aagtgcttga tttttggtct
    15901 tggctagtgg aagcgatcaa atctcctaca agtaagttgg aaacaagtat cacacacagt
    15961 tacacagcct ttctcttgct cattctgttt tctgcatctt cctttttctt tagtatctat
    16021 cacatcaaac atgcttacta tggacatata gcaagcatta acagtcgctt ccctgagcag
    16081 ctagctcctt taactctttt ttctatcatc tctatcctag tagcgacaac actcttcttc
    16141 ttttcattcc tcttgggtag tttcgttgtg agacgattta tccaccagga aaaggactgg
    16201 acgctagaca aggttctcca acaatatagt caactcttgg caattccaat cttcctcact
    16261 gctattgcta gtttctttgc tttctttgat agcctacgat ttacagctct cttgtgtgtg
    16321 attagcattg gaatcattct gcttgccagt ctccatatca ttacaagacc aagtcaagca
    16381 agtgaaaccg actccttcta tcaattattc ttgtctgtcc ttgtgaacgg agttattatc
    16441 ctcctcttct ttgtagctga agtggcactg attggagatt atcttcgtat cttggccttt
    16501 ctttaaaatt caatcctgtc atccttggca ggattttttc tatgtcaaaa aagcaagtcg
    16561 attgacctgc ttctgcttta cttttcttgt gctaatgttt taaaatcttg tactaggatg
    16621 ggttgtattt ctatttgatt ggcgtctagt tggtggtaaa aagatggggg taatacctct
    16681 aagaattttg catagtccaa gcgagctatg gattcatagt cttctggttt agagtcgtct
    16741 cctgtgattt gaaccaagtc aatctcccac tggacttcct tatccaccaa ttgctcaata
    16801 taggctgcag gaacaaacgg ttctctcggt aaaactgtct tgactccttg agctagatgg
    16861 taaacgccat gcacttttcc ttctccatcc tgatagaagg aaactctcgc aaagtaggca
    16921 tctgtctctt gaaccgcacg cacacgcgct tcaaactgag ccaagccatc tgcctctaaa
    16981 aagcttttca agttctcacg actaaagaaa ataggattaa aaattccttg gcaaatcgta
    17041 aaacgagcta cagggtctgc tagataggct tgaatacttg cttggaaata agcttcaaaa
    17101 tcaaaaccat ctagcccttc aatatcagtc cctgtataag caagcaaagc atctaaaaat
    17161 gacttgataa tctgccagtc tgtctttgtt agtaggtcag gaagatcgac acggtaagcc
    17221 ttttgaccat cagcataact gaccttaaaa agaaattgtg attgccccac tatcgcacac
    17281 tcaatatact cgagacgatt aagaggctga cggagataga ctacatcata gctatgtgac
    17341 tccaaaccgt ctagcaaggc caagatcgac ttggcattca aaatctcttg ttctcctaaa
    17401 atgctctgtt tatttggaat aaaaaatgtt ttcgccataa ctggactcct ttgaaatcgt
    17461 ttacatacag tataccttat ttttctgaaa gatacaaaaa caaactttag atttttgagt
    17521 acaaagcata gaaaaacagc ccctgaggac tgtttgatct tatacagtag ctgcctgatc
    17581 caagctttca ccgatagcgg ctaggcgctc aatcacttca gcttgtgtca attcattttt
    17641 tgaaacatag cggttacgtg ggtgaacacg gcactcgtgt gagcatccac gaaggtactt
    17701 gtcttcattt tcttctgatg tcaagatacg acggttacag aagggatttc cacagttgac
    17761 ataacgttca catggtgttc catcaaacca gtctttccct acgatggttg ggttgacatg
    17821 gttgacatca acggcgatac gctcgtcaaa tacgtacatt tttccatccc aaagctcacc
    17881 ttgaacttct gggtctttac cgtaagttgc gattcctccg tgcaattggc cgacatcttt
    17941 gtagccttca cggaccatcc agcctgagaa tttctcacag cgaacgccac ctgtacagta
    18001 aaccacgaca cgcttgtcca tgaatttttc cttgttatca cggacccatt gtggtaactc
    18061 acggaagttg cgaatatctg ggcgaatagc tccacggaaa tgtcctaggt cgtactcata
    18121 atcgttacgt gtgtcaagga caacggtatc tttatcaaga agcgcttctt tgaactcttt
    18181 tggagacaag taagcacctg ttgtttcaag tgggttgatg tcattgtcaa agtcgttgtc
    18241 ttccaaacca aggtggacaa tttctttctt gtagcgaaca aacatcttct tgaaggcttg
    18301 ttcattttct tcgtcaatct tgaaccagag ttcttccatt cctggaaggc tgtgaacgta
    18361 gtccatgtat ttttgagttg tttcatagtc acctgaaact gttccgttaa ttccctcgtc
    18421 agcgactagg atacggcctt taaggccgat tgatttacag aaagccaagt ggtctgcagc
    18481 aaattgctct gcattttcaa ttggagtata aaggtagtaa agtaagacac gaatatcttt
    18541 tgccataaga tttgttctct tttctattct taaattttct aaatttttta tttatctaca
    18601 ctagtatacc tgcttgagaa aacgaatgca atttatttga ctggaaattg tagagggttc
    18661 tcgaaatttc ctgaatggtt aaaataagga caagagaaaa catggatatc tatatccttg
    18721 tgccaaaaaa accactgccc tccccagacc aacctgagga aagcagtgat tcttatttta
    18781 ggagttagga atgaatacac gaaatcaatt tagctgatta ttttttgttt ttcaagaatt
    18841 catcgtattg tttttgcatt tcgttcaata ctttttcgta ggcaccttca gatttcaatt
    18901 tttccatcaa ttctggaatc gctttatctg ggtctacagt accagtgttg atagctgtat
    18961 caaattgttg cattgtgtta gcaatagctg agatttcaga tttcacattg tcagtattga
    19021 agataaatcc aagcgctgga gattctttag cttctgccaa ttctttctta gaattttcga
    19081 tttgttggtc tgtaacgttt tcgttgatgt aaaggatcca gttgttacca gtgttccatc
    19141 cacccatgtg agtgtttcct ttgtagccat caagaacgcg aacacggttt tctttacctt
    19201 caattttttc ccagttcttg ccttctggac cgtaaacaag accgttcaag agttctggat
    19261 tcgtattcaa gaggttcaag atttccattg atttttcttt gttcttagag ttgtttgaga
    19321 tgacaaagtt agcaacttgt gttgtttggt ttttcttgat gaagttagta attggtttga
    19381 tttggatatc tttgttggca acacgtgaaa gcaagctgtt accgtagtca gctggtccta
    19441 ctgtttcttc acgaacgaac caagtatctt gttgaaggtc aaaggaagta tcgcttgttg
    19501 cgacatcttt tggaatgtag ccagcttcat agaatttgtg aagagtcttc aagtgttctt
    19561 tgaaacgagg cacttcgtaa cggtttacaa ctttagtagt atcgccttca aggtcaataa
    19621 cgaatggaag cccgtttgct actgggtagt caaagttatc agatgggatg aaaactttac
    19681 caatagcaaa tggtactacg tctggagctt tttctttaat ttgtttcaag actggctcaa
    19741 gagtttcgta agaagtaaca cctgaaatat cgataccata tttggcaagg agagttccgt
    19801 tgaaggcaaa gttttgagat gatgcaacgt tggctgcaac tggaacagcg taaattttac
    19861 cgtttacagt attacccttg atgtaagctg ggtcaagtgc cttgtaaagg tctttacctt
    19921 cttttttgta caattctgtc aagtcagcat aagcaccttt ttgagcattt acaatatagt
    19981 tatctgcaaa ggcgatatca tagttttcac cagatgatgt gataactgac attttcttac
    20041 catagtcacc ccagccaagg tattggatat ccaatttagc accaactttt tcttcgatga
    20101 ttttgttggc atttgctaac aattcatcca agttatctgg tttgtcaccg atttggtaca
    20161 ttttgataac aggtttgtca cctgaatcag cagctttttt gctgttacct gtcaagttgc
    20221 cacaagcagc aagacctgca gccagagcga ctacactagc agatgcaaaa gcatattttt
    20281 tccagttttt catgataaaa actccttttt ttatttttaa acttataaac aatgtaatga
    20341 tcttatactc aatgaaaatc aaagagcaaa ctagaaaact agccgcaggc tgctcaaagc
    20401 actgttttga ggttgtagat aagactgacg aagtcagtta catatatcta cggcaaggcg
    20461 acgttgacgc ggtttgaatt tgattttcga agagtattaa cttcacacaa gggaagttgg
    20521 gaactgagaa atgttctttt tcaataagca ctattctttc acaccaccga tagtcaaacc
    20581 ttttacaaag tagcgttgga agaatggata taaaatcgcg attggaaggg ttgcaaccac
    20641 aaccatggcc atacgacctg tttctttcgg tagagcaact cccagttgac cagtcaagcc
    20701 gaccgctttg gcaatgtagt ccatattttg ttggatttgc atgagcaaat attgcaatgg
    20761 atacaagtta tcactcttga tgtaaagaag ggcgttgaac cagtcattcc agaaaccaag
    20821 agctgtcaaa agcgtgatgg ttgcgatacc tggtagtgac aatggcaaac agatttggaa
    20881 gaaaatccgg gcctcactgg caccatcgat acgagccgat tcgagaatgg cttctggaat
    20941 ggtcttcttg aagaaggaac gcatcaagat gatattgaat ggtgagagaa gcattggaac
    21001 aatcaaggcc caaacagtgt ccccaagctg aagtacacgg gtcaccatga tataacctgg
    21061 taccaaacca gcgttgaaca acatactgag aaggacgaag atggtaaaaa atctgcgata
    21121 cttaaaggtt gtccgtgaaa tagcgtaggc ataggttgtt gtgataaaga catttgtcaa
    21181 tgtcccaact acggttacaa agacagagat gaagagggct tgtaggattt tatccttaaa
    21241 ctgtgccaaa aactcaaaac cgtctaagcc aaattgggat gggaagaagc tatagccgta
    21301 ttggaggagg cttttctcgt ctgtcactga aataatgata acgaatacaa aaggtaggat
    21361 acaagagagg gcaatcaaac ccgaaatgat actgaagaag atatctgctt tcttactgaa
    21421 ggagtgaatg ccgacattat caattttttc ttttttaatt ttcttttttg ccatattctc
    21481 ctcctttcta gaacaaagct gagtttggat cgactcgtct tgcaagcaag tttgatagga
    21541 taaccagaat caaaccaaca acggattggt aaagaccggc tgctgcagcc ataccgatat
    21601 ctgctgtctg agtcaaacca ttaaagacat atacgtccaa aacgttggtt acattgtaaa
    21661 gctgaccagc attgtgtggg atttgataga agagaccgaa gtctgcgcgg aagatatttc
    21721 cgactgcaag gatggtcaat acagttacaa gcggagtcaa ctgaggaatg gttacgttgc
    21781 gaatacgttg ccacttgcta gctccgtcca ctgtcgctgc ttcgtagtag gttggatcaa
    21841 ttcccatgat cgtcgcatag tacatgacac tgctatatcc aaatcctttc caaataccta
    21901 ggaaaagtag gagatagggc cagatgccca ggtcagcgta gaaattgact tctttgagac
    21961 caagactttc caatagatga ttgaacaccc ctttatcaat atttaggaag gcatctgtaa
    22021 agaaactgat gataacccaa gacaagaagt aagggaacaa catagaagtt tgaaaaatct
    22081 tcaccattct cttagaacgg agctcgctga ggataatggc gatccctaca gatacaacta
    22141 aacctagaaa gataaagcca agattgtaga ggacagtatt tcgtgtgata ataaaggcgt
    22201 ctcttgaact aaataagaat ctaaaattat cgagtccgac ccatttacta tttatgatac
    22261 tatctatgaa accattactg gtcatgtggt agtctttgaa ggcaaccacg ttcccaaata
    22321 ctggaatgta aaagaataga atcaaccaga gtgcccctgg caaaaccatc aagagaaaga
    22381 tccagttgtc tctcaatgtt tttgaaaact ttttcataat ttcctccctt tttattttga
    22441 tatccatcta aaaattcttt tttagacttt tgataacgat tacattatta gtatactcct
    22501 atttgcaggt taggttaaac tcctaattat agaaaaaact ccacaaatta tgtagcagat
    22561 ttaaaacttt atcaccacta tcaaacaaat gtcctaaatc aattgtttat tttatctcta
    22621 ttagcccagt gatggcgtca ctctgttata agcatccaac aacggggtat actgaaaaat
    22681 ctccagacta gggaactcag cgatagttcc taatctggag atttttaata tgttattagg
    22741 cgtttgcttt caacttagca ataacctctt taagattatc aatcaactct gctgcagtat
    22801 gctcagagcc tttttcatct gccaagaaca aaactgcttt ttgaagttct ttttgagagt
    22861 tttcaaggac atccttatct actgtttcaa ggtttgagtc tttaagaagt ttacttaatt
    22921 ccttggctaa tttcttgagt ttgatttgca gactcatctt ctcctgctgt ttctttgccc
    22981 gctgtttgtc ctccatcctt agttgctgac tggctttcct taatggactc tagggaagca
    23041 atggcatctt tgactgtttg caagatatca cgtaaacctt gctctgtcaa actatcatct
    23101 gtaagagctt tcttagcctc tgccaaaacc agacgtgctg aatctgtggt aggattcgat
    23161 acacctgtca atgatctcaa aagattttct aaggtttgag tctgcttact aatactagac
    23221 taaaatcaaa aagcattaca taacagtgat atgaaatcaa ctaaagaaga aatccaaacc
    23281 atcaaaacac ttttaaaaga ctctcgtaca gctaaatatc ataaacgcct tcaaatcgtt
    23341 ctatagtaaa atgaaacaag aacaggacaa attgatcagg acagtcaaat cgatttctaa
    23401 caatgtttta gaagtagggg tgtactattc tagtttaaat ccactatatt tggggagtga
    23461 tagaaaagcc cttcataagc cagtctactt gttcaggtgc gagagctttg acatcctttt
    23521 ctgtactggg ccaagtcagt tttccgttct caaagcgttt atatagtatc caaaatcctt
    23581 gaccatccca gtaaagggct ttaaagcggt ctttacgtcc accacaaaag agaaagactt
    23641 gaccggagaa aggatccaat tcaaagtggg ttttaacgag ataagccagt gaatcgattc
    23701 cttgtatcat atctgtcttg ccacaaacaa ggtgaacttg acctaaatca cttagttgaa
    23761 tcatcatagt acaatacttt tcctccgata attatttttt atctagtata ctggaagttg
    23821 gggaattagg atagatacct tgttatgacg cgcttacgta acttgtaact agctgcctag
    23881 tttgatcttt gcttcttcat tgattagcag cagatttcaa aatgataaaa acgtataata
    23941 gtgggtgtag aaactcttgc tactatgcgt tttattatgg aaagacttat tggactttct
    24001 ctcaaatcga gtttttactc aattttctta cttgattggg attgaaattc caattaattt
    24061 ctctgagtag agtgtcttga tattggcttc atcaacagag gccttatcaa ttttacgttt
    24121 caagaaaaat tcttgaatgg tttcgatttc aggctcacga atagcacggt gtttgtttga
    24181 gatgaggatt tcatagtgaa gcggagcttg ggtaaaaata acatctgtat tccctgcaga
    24241 ataaacctca acaagggttg catcggtact ttctagctga ctttttacaa gttgcgagtg
    24301 tgagtttgtc gtattgataa gcttcataat atttcctccg attttctaat tctattatag
    24361 cactttttga ataaagtcgc ttgatttata ctcaatgaaa ataaaagagc aaactaggaa
    24421 gctagccgca ggctatactt gagtatggta aggcgacgct gatgtggttt gaattttatt
    24481 ttcgaagagt attagtcaat cttatgctgt tttttccaag attcaatggc ccatttatgg
    24541 ctaccacgtt taaggttttt gatagcctcg tcaataggga accaggcaat atgattaaag
    24601 ttttctagtg gcttttgtac ttctttgaaa ggagttgctt catagaggta ggcaggattg
    24661 tagtagtagg tatcacgatg acgagaatag aaatattcgt cagcttgtcc gtaataggta
    24721 ccaatttctg ctgtgaaacc aagctcttca atcaactcac gctttagggc ttcctgatga
    24781 ttttcacctg cttcaatttc tccacatggt aggaaccaag caccatttgg ttcttgaaca
    24841 agaacaattt gtttttgttc aggattaggg ataactgcat atacgccata gcgagcaata
    24901 tagtctgtat tcgctttttt tctccgaaag ttgggtttgc cattgcattt tcctcattat
    24961 ctagtatcgt tattattata gt
//
LOCUS       DAVLBE010000027        22550 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.027, whole genome shotgun sequence.
ACCESSION   DAVLBE010000027 DAVLBE010000000
VERSION     DAVLBE010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22550)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22550)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22550
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.027"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            <1..409
                     /locus_tag="VXB91_001197"
     CDS             <1..409
                     /locus_tag="VXB91_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV0470657.1"
                     /translation="GNGIAWKSRKYLIDNPTIIIGRVGAYCGNVRTTHGKVWISDNAI
                     YIKEFKNSDFNLVFLLELMKVIDFSKFADFSGQPKITQKPLENQKYILPPLALQNEFA
                     DFVALVDKSQLAIQKSLEELETLKKSLMQEYFG"
     gene            469..705
                     /locus_tag="VXB91_001198"
     CDS             469..705
                     /locus_tag="VXB91_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HEV0470658.1"
                     /translation="MVVKTRKQGNSITITIPSEFNIPSGVKYEAKLLPSGEIIFTPEE
                     LGQQVSYVSDDAFDLNLDKIFDEYDDVFKALVEK"
     gene            702..1115
                     /locus_tag="VXB91_001199"
     CDS             702..1115
                     /locus_tag="VXB91_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HEV0470659.1"
                     /translation="MTIYLTEKQIEKINALAIQRYSPNEKIQTVSSSALNMIVNLPEQ
                     FVFGKSLYPTIFDKATILFVQLIKKHVFANANKRTAFFVLVKFLQLNGYRFSVTVEEA
                     VKMCVTIAVEALTDEKMTSYSKWVSEHSVREKVKK"
     gene            1233..2198
                     /locus_tag="VXB91_001200"
     CDS             1233..2198
                     /locus_tag="VXB91_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEV0470660.1"
                     /translation="MESKVTIIMQEMLPLLNNEQLLALRESLEHHLVDGKKQQKYSNN
                     NLLQLFITAKQVEGCSSKTIRYYQRTIENLFNAIKESVTQLTTDDLRSYLANYQSEKD
                     CSKANLDNIRRILSSFFAWLEQEEYIIKNPIRRIKKIKTEQNVKETYTDEHLEIMRDN
                     CENLRDLAIIDLLASTGMRVGELVQLNRSDIDFENRECVVFGKGKKERPVYFDARTKI
                     HLRNYLNDRKDSHPALFVTLVGKAQRLGIAGVEIRLRKLGDKLGIQKVHPHKFRRTLA
                     TKAIDKGMPIEQVQKLLGHSKIDTTLAYAMVNQNNVKHSHQKFIS"
     gene            2232..3338
                     /locus_tag="VXB91_001201"
     CDS             2232..3338
                     /locus_tag="VXB91_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV0470661.1"
                     /translation="MKKVKLGQVATFINGYAFKPQDWSSEGKEIIRIQNLTKTSKGIN
                     YYSGTIDKKYIVEAGDILISWSGTLGVFQWCGRSAVLNQHIFKVVFDKIDIDKSYFKY
                     VVEKGLQDAVKHTHGSTMKHLTKKYFDNIIVPYTNLGEQQRIASELDLLSKLILRRQE
                     QLEELNLLVKSRFNEMFGENKIFESIDNLFDIIDGDRGKNYPKSDELFSEEYCLFLNT
                     KNVTKNGFSFDTKQFITKTKDKLLRKGKLERYDIVLTTRGTVGNVAYYDELIKYKHLR
                     INSGMVILRPKTPNLNQKFIIHVLRNNNYSRVISGSAQPQLPITKLKKILLPLPPLAL
                     QNEFADFVVQVDKSQFACEIAIKVWRNSLKFSII"
     gene            3368..6718
                     /locus_tag="VXB91_001202"
     CDS             3368..6718
                     /locus_tag="VXB91_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEV0470662.1"
                     /translation="MGNFSFLLKNDEYESFSKPCIEAENMIATSTVATAFMARRALEQ
                     AVHWIYSHDSYLEAPYRATLSSLVWDDDFRDIVDSELHKQIVLLIRWGNHAAHGGEIK
                     EREAILALHHLYQFVNFIDYCYSNEFVERYFDEKCLPLSANIKYRETPQSMIKLQDSL
                     PELPDFHEQMAAQSVEVQETYTEKRETAAQRQDVPFHIDQLSEAETRKLFIDIDLRLA
                     GWIFEENCRVEIAVDGLKHGSGIGYCDYVLYGKNGKILAIVEAKKASVNPEVGEVQVK
                     EYAEALEKHIGYQPICFITNGLKHYILDGPNRRQIAGFYSQEELQLVMDRRHLQKPLE
                     DISSKIRDDISGRHYQKHAIASVCEAFSNHRRQALLVMATGAGKTRTAVSLVDILSRH
                     NWVKNVLFLADRTSLVKQAYDSFRKLLPDLSVCNFLEDKEGAQSSRMVFSTYPTMIGA
                     ISGQEEVNQRPFTVGHFDLIIIDESHRSIYQKYKSIFDYFDARIVGLTATPRQDLDKN
                     TYGFFNLENGVPTYAYDLEEAVKDGYLVAYHSIETKLKLPTDGLHYDDLSEEEKEHFD
                     SKFEDDSCEKDIDGSVFNSFVFNKSTVEIVLNELMTRGIQTASGDEIGKTIIFAKNHD
                     HAEYIRGIFNNRYPEKGSDYAQVIDYSIKHYQTLIDDFKIKEKYPQIAISVDMLDTGI
                     DVPEVVNLVFFKKVRSKTKFWQMIGRGTRLCKDLFGPEQDKENFLVFDYGDNFDYFRA
                     DPRDGEGRHIVSLTQRLFNIKVDLIRELQGLQYQEDQFARAYRQQLVSELQGRIESLN
                     ELDFRVRMVLDTVYSYRKLESWQNLTAVTSETIQKNLSLLLFDEDKEDEMARRFDLWL
                     LHIQLGQLTAKSSTVHISQVMKTARALSAIGNIPQVFEQAEIIRKVQEPEFWKEVNLS
                     DLEKIRLAIRDLLQFLDKTDRKPYYVNFEDRILSTVHETTAFLQVNDLRSYNEKVEHY
                     LKTHLDEESISKLYHNKKLTSDDMLALEKLLWEKLGSKADYQSHYENKAIPRLVREII
                     GLDRESANRIFSKFLSDENLNARQISFVKLIVDYIVENGFLETKVLTQEPFKSYGSVQ
                     LLFQHQLPVLRNIVQIIELINNRAGEAA"
     gene            complement(7224..7694)
                     /locus_tag="VXB91_001203"
     CDS             complement(7224..7694)
                     /locus_tag="VXB91_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEV0470663.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQALLAENDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(7711..9984)
                     /locus_tag="VXB91_001204"
     CDS             complement(7711..9984)
                     /locus_tag="VXB91_001204"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HEV0470664.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELEVKLPHKIELEKPQLNLVQPQGKAELIAEAEEKLTHINSSYTLNDY
                     FLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRCRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHIHKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCETFSLGQEEQ
                     AIQNQYPDKDFERYGKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
     gene            10331..13432
                     /locus_tag="VXB91_001205"
     CDS             10331..13432
                     /locus_tag="VXB91_001205"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HEV0470665.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLLGLEMTVFVDDQEVNLRFLALSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAVIVSYFDRVESLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQERFPQALDNLEKLISG
                     ISYDLDTSLKLPRFNPARPAVEELRERAELGLVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGRSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YELSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     ETEGIHLKIEEIDLEDKETLALFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDSALEDILAPTYGIMLYQEQVMQVAQRFAGF
                     SLGKADILRRAMGKKDASAMHEMRASFIQGSIEAGHTAEKAEQVFDVMEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQVMLNYSNSDYLIDALEAGFEVASLSINTIPYH
                     DKIANKSIYIGLKSIKGLSKDLALWIIEHRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQESEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVQKIKVIRTKKGENMAFLQADD
                     SKKKLDVTLFSDLYRQVGQEIKEGAFYYVKGKIQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHESDQEISRILEQFKGPIPVIIRYEEEQKTIVSPHHFVAKSNELEEKLNEIVMKT
                     IYR"
     gene            13515..14522
                     /gene="pfkA"
                     /locus_tag="VXB91_001206"
     CDS             13515..14522
                     /gene="pfkA"
                     /locus_tag="VXB91_001206"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HEV0470666.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEAGFKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     S"
     gene            14581..16086
                     /gene="pyk"
                     /locus_tag="VXB91_001207"
     CDS             14581..16086
                     /gene="pyk"
                     /locus_tag="VXB91_001207"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HEV0470667.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATSSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
     gene            complement(16821..17046)
                     /locus_tag="VXB91_001208"
                     /pseudo
     CDS             complement(16821..17046)
                     /locus_tag="VXB91_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001824185.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            17894..18766
                     /locus_tag="VXB91_001209"
     CDS             17894..18766
                     /locus_tag="VXB91_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HEV0470668.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQHATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPADDGFLFVEKLTFEEPYQAIKFASKEDCYKYLGTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            complement(18912..19256)
                     /locus_tag="VXB91_001210"
                     /pseudo
     CDS             complement(18912..19256)
                     /locus_tag="VXB91_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            19399..19711
                     /locus_tag="VXB91_001211"
                     /pseudo
     CDS             19399..19711
                     /locus_tag="VXB91_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521917.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            19715..20431
                     /locus_tag="VXB91_001212"
                     /pseudo
     CDS             19715..20431
                     /locus_tag="VXB91_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
     gene            complement(20561..21376)
                     /locus_tag="VXB91_001213"
     CDS             complement(20561..21376)
                     /locus_tag="VXB91_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HEV0470669.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTNLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQITNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWISAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(21373..22278)
                     /locus_tag="VXB91_001214"
     CDS             complement(21373..22278)
                     /locus_tag="VXB91_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HEV0470670.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGILFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSILVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSYLSSAKKVFQVFVQAIDEFFDTGRYLVFGCLFASIIQVYVPTRILTSISATPLFA
                     ILLLMILAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLVYSLLIGVIL"
BASE COUNT         7199 a         3785 c         4734 g         6832 t
ORIGIN      
        1 tggaaatggc attgcttgga aaagtcgaaa atatttaatt gataatccta ctatcatcat
       61 tggtcgtgta ggtgcatatt gtggtaatgt aagaactacc cacggtaagg tatggataag
      121 tgacaatgct atatatataa aagaatttaa gaattccgat ttcaatcttg tatttttatt
      181 agaattaatg aaagtaattg attttagtaa atttgctgat ttctcaggtc aaccaaagat
      241 aactcaaaaa ccattagaaa atcagaaata tatcctcccc cctctagccc tccaaaatga
      301 gttcgcagac tttgtagccc tggtcgacaa atcacaattg gcaatccaaa aatctctgga
      361 agaacttgaa actttgaaga aatctctgat gcaggagtat tttggctgat attctgccat
      421 tgtaattacg gtaatgattt gttataatac ttcaaaggag gaaatcagat ggtagtaaaa
      481 acaagaaaac aaggaaattc aatcaccatt acgattccaa gtgaatttaa tattccaagt
      541 ggtgttaaat acgaagcgaa attgttacca agtggtgaga ttatctttac tcctgaagaa
      601 ttggggcagc aggtttctta tgtatctgat gatgcctttg acttaaattt agataaaata
      661 tttgacgaat acgacgatgt tttcaaagct ttggtggaaa aatgacaatc tatctaacag
      721 aaaagcaaat tgaaaaaata aatgctttag caattcaacg gtattctcca aatgagaaaa
      781 ttcaaacagt tagttcttct gccttaaata tgattgtgaa cttaccagaa caatttgtct
      841 ttgggaagtc tctttatcca acaatttttg ataaagcaac gatactattt gtccaattga
      901 taaagaagca tgtttttgct aatgctaata aaagaactgc tttcttcgtt ttggtcaaat
      961 ttttacaatt aaacggctat cgtttttctg taacggtaga agaagcagta aaaatgtgtg
     1021 taaccatcgc agtagaagct ttaactgatg aaaaaatgac aagctactcc aaatgggttt
     1081 ctgaacattc tgttagagaa aaggtcaaaa agtaacctag tatgctggat ttgaatgagc
     1141 acaagaaaat aaatgaacag acaatattag aattctgtaa tgcagaaact gatattgtct
     1201 ctttttattg atgaataaga aagtgagaaa ttatggaatc aaaagttaca attatcatgc
     1261 aagaaatgtt acctctttta aataatgaac aattactagc gttgagagag agtttagaac
     1321 atcatctagt agacggaaaa aagcagcaga agtattcgaa taataacctg ttgcaactat
     1381 ttattaccgc caagcaggta gagggctgta gctcaaaaac aattcgttat taccagagga
     1441 cgattgaaaa cttgtttaat gctattaaag agtctgtgac acaactcaca acagatgatt
     1501 taaggagtta tttagcaaat taccagtctg aaaaggattg tagtaaggca aatttagaca
     1561 atattaggcg tatattgtct tctttttttg cttggcttga gcaagaggaa tatatcatta
     1621 aaaatcccat tcgacggata aagaaaatta agactgagca aaatgtgaag gaaacttata
     1681 ctgatgaaca tttggaaatt atgcgtgata actgtgaaaa tttgagagat ttggcaataa
     1741 tagacctact agcatcgaca ggtatgcgtg taggggagct tgtacagttg aatcgttcag
     1801 atattgattt tgaaaacaga gagtgtgttg tctttggtaa aggaaagaag gagagaccag
     1861 tatattttga cgctcggacg aaaattcatt taagaaatta tcttaacgac agaaaagata
     1921 gtcaccctgc tctttttgta acgctagttg gaaaagccca gagacttgga attgctggtg
     1981 tagagattcg cttaagaaag ttaggagaca aactcggcat acaaaaggtt cacccacata
     2041 agttcagaag aactttagcg actaaggcaa ttgataaagg tatgcctatc gaacaagtcc
     2101 aaaaactgct aggtcatagc aagattgaca caaccctggc ctatgccatg gtcaatcaaa
     2161 ataatgtcaa gcattcacac caaaaattca tctcttaaaa gcaaatcccg atattccgag
     2221 gaggtggttg catgaagaaa gtgaaattag ggcaagtggc tacttttatc aatggctatg
     2281 cttttaaacc tcaagattgg tcatctgaag ggaaagagat tatcagaata cagaatctga
     2341 ctaaaacttc aaaagggata aattattatt cgggtacgat tgataaaaaa tacattgttg
     2401 aagctggtga tattcttatt tcgtggtcgg gtacattagg ggtttttcag tggtgtggaa
     2461 gatccgcagt attaaatcag cacattttta aagtggtttt tgataagata gatatagata
     2521 aatcgtattt taaatatgtt gttgaaaaag gtttacaaga tgctgtaaaa catactcatg
     2581 gttccacaat gaaacattta actaaaaaat attttgataa tattatagtt ccatatacaa
     2641 atttgggaga gcaacaaaga attgcaagtg agctggattt gttaagcaag ctgattttaa
     2701 ggagacaaga acaacttgaa gagcttaatc tacttgtaaa atcccgattt aacgagatgt
     2761 ttggggaaaa taaaatattt gaaagcattg ataacttatt tgatattata gatggtgata
     2821 ggggcaaaaa ttatcctaaa tcagatgagt tgtttagtga ggagtactgt ttatttttaa
     2881 atacaaagaa tgttactaaa aacggatttt cattcgatac aaagcaattt atcactaaaa
     2941 caaaggataa attacttcga aaaggcaaac ttgagcgtta tgatatagtc ttgacaacaa
     3001 gaggtactgt tggaaatgta gcgtactacg atgaattaat aaaatataaa catttacgta
     3061 taaattcagg tatggtaata ttacgtccca agacaccaaa tctaaatcag aaatttatta
     3121 tccatgtttt aaggaataat aattatagtc gagtgatatc aggaagtgct cagcctcagt
     3181 taccaattac aaaattaaaa aaaatacttc tccccctccc cccactagcc ctccaaaatg
     3241 agttcgcaga ctttgtagtc caggtcgaca aatcacaatt tgcttgtgag atagctataa
     3301 aagtgtggag aaatagcttg aaatttagta taatatagct aaactatttg tttaaagtga
     3361 gaaaaaaatg ggaaatttta gctttctttt aaaaaatgac gaatatgaat ctttttcaaa
     3421 accttgcatt gaagctgaga atatgattgc tacatcaact gtggctactg cctttatggc
     3481 gcgtcgtgct ttagagcagg ctgtccattg gatatatagt cacgattcat atttagaagc
     3541 tccctatcgt gctactctat cttctttagt atgggatgat gattttaggg atatcgtaga
     3601 ttctgaactc cacaagcaga tagttctgtt gattcggtgg ggaaaccatg ctgctcatgg
     3661 tggtgaaatt aaggaacgag aagcgatttt agctttgcat catttgtatc agtttgttaa
     3721 ttttatcgat tattgttaca gcaatgagtt tgtggagcgt tattttgatg agaagtgctt
     3781 accactttca gcaaacatca aataccgaga aactccacaa tctatgataa agttacaaga
     3841 cagtttacca gaactgcctg attttcatga acagatggct gctcagtccg tagaagttca
     3901 agagacttat actgaaaaac gtgagactgc agcgcaacgg caagatgtgc ctttccatat
     3961 tgatcaatta tctgaggcag agacaagaaa gctctttatt gatatcgatc tccgtttagc
     4021 aggatggata tttgaagaaa actgtcgtgt tgagatagcc gttgatggtc tcaagcacgg
     4081 ttcaggaatt ggttactgtg actatgtact ttatggtaaa aatgggaaaa ttttagcgat
     4141 tgtagaggct aaaaaagcct ctgtcaatcc agaagtaggg gaagtacagg tcaaagaata
     4201 tgctgaagct cttgagaaac atatcggcta tcagccaatt tgctttatta caaatggctt
     4261 gaagcactat atacttgatg gtccgaaccg ccgccagatt gcaggctttt actctcaaga
     4321 agaattgcaa ttagtgatgg atagacgtca tcttcaaaaa ccacttgagg atatttctag
     4381 taaaattagg gacgatattt ccgggcgtca ctaccaaaaa catgccattg caagcgtttg
     4441 tgaagctttc tctaatcatc gtagacaggc acttttggtt atggcaactg gggctgggaa
     4501 aactcgtaca gcagtttctc tagttgatat cttatcacgt cataactggg taaaaaacgt
     4561 tctcttctta gccgatagaa cttccttggt taagcaagcc tatgattcgt ttagaaaatt
     4621 actcccagat ctttccgttt gtaacttctt agaagataaa gaaggagctc aatcaagtcg
     4681 catggtcttt tcaacttatc cgaccatgat tggagcgatt agtggtcaag aagaagtaaa
     4741 tcaacgccct ttcactgttg ggcattttga ccttatcata attgacgaat ctcaccgttc
     4801 tatttatcag aaatacaagt ccatttttga ttattttgat gcaagaattg taggcttaac
     4861 agctactccg cgtcaagatt tagataaaaa cacctatgga ttctttaatt tggagaatgg
     4921 ggttccaaca tatgcatatg atttggaaga ggctgttaaa gacggatatt tagtagccta
     4981 tcattctatc gaaaccaaac tgaaactacc tacggatggt ctacattatg atgatttgtc
     5041 cgaagaagaa aaggaacatt ttgatagcaa atttgaagac gatagctgtg aaaaagatat
     5101 tgatgggagt gtatttaatt cctttgtttt caataaaagt acagtagaaa ttgttttaaa
     5161 tgaactcatg acaagaggaa ttcagacagc ctcgggtgat gaaattggta aaactattat
     5221 ttttgctaaa aatcatgatc atgcggaata tatcagaggt atttttaaca accgctatcc
     5281 tgaaaaaggg agcgactatg ctcaggtgat tgattatagt attaagcatt atcagacctt
     5341 gattgatgat tttaaaatta aggagaagta tcctcaaatt gcgatttctg tcgatatgtt
     5401 agatacaggt attgatgtac cagaggttgt taatttagtc ttcttcaaga aagtacgctc
     5461 taaaactaag ttttggcaga tgattggtcg aggaacccgt ctatgtaaag atttatttgg
     5521 acctgagcag gataaggaaa acttcttggt atttgattat ggggacaatt ttgattattt
     5581 tcgtgcagat ccaagagatg gagagggtcg tcacattgtt tcgttgactc agcgtttatt
     5641 taatatcaaa gtggacttga ttcgagaact tcagggactc caataccaag aagatcagtt
     5701 tgcgagagca taccgtcagc agcttgtctc ggaacttcaa ggtcgtatag agagcttaaa
     5761 tgagttggac ttcagggttc gtatggtttt agatacagtt tatagctata ggaaattgga
     5821 aagttggcag aatctaactg ctgttacaag tgaaaccatt caaaaaaatc tctctctgct
     5881 tttatttgat gaagataaag aagatgagat ggcgaggaga tttgatttgt ggttgcttca
     5941 tattcagttg gggcaactga cagctaaatc ttccactgtt catatttccc aagtgatgaa
     6001 gacggctaga gctctttctg ctattggcaa tatcccgcag gtttttgagc aggctgaaat
     6061 tatcaggaaa gtacaggagc ctgaattttg gaaagaagtt aacttgtctg atttggaaaa
     6121 aattcgtctt gctattcgag atttattaca gtttttggat aaaacagacc gtaaacccta
     6181 ctatgttaac tttgaagatc gtatactctc cactgttcac gagaccacag catttttgca
     6241 ggtcaacgat cttcggtctt acaatgaaaa agttgagcat tatttgaaaa ctcatctgga
     6301 tgaggagtcc atttctaagc tataccataa taaaaagttg acatctgatg atatgcttgc
     6361 acttgaaaaa ttgctttggg aaaaattagg tagtaaagca gactaccaaa gtcattatga
     6421 aaataaggca attccgagat tggttcgtga gattattggc ttagatagag agtctgccaa
     6481 tcgtattttt tctaaatttt tgtcggatga gaatcttaat gccaggcaga tttcatttgt
     6541 aaaattgatt gtagactaca ttgtagaaaa tggtttttta gagacgaaag tgttaacgca
     6601 agagccgttt aaatcttatg gttctgttca actactcttc caacaccaac taccagtact
     6661 tcgtaatatt gttcaaatca ttgaacttat caataatcga gctggagaag cggcttaaat
     6721 tctaaagtga ttgccatgct gagactcatt taaaattaaa aagagtagaa atttatgcta
     6781 tatatgagaa gttttattag gaagaatgtc atcgttttcc tagaatacag tatcagttgt
     6841 taagtggttg ataaatttca aagtagatac ttgtaccacg atgtttgttg atcgagttat
     6901 taacaaaaga gctactttga ttttaaagaa atagaaaaca aaaagccgag caagaattca
     6961 attgcaggag aaaatgaaat aatactcaat gaaaatcaaa gagcaaacta ggaaactagc
     7021 tgcaggctgc tcaaaacact gttttgaggt tgtagatgga agctgacgcg gattgaagag
     7081 attttcgaag agtataaatc ttcctaggat aaagcaaaac gcatagtatc aagggttttc
     7141 aacacttgat actatgcgtt ttctgatgtt aaagactttc taccaggttt tttaaaagca
     7201 taattgttag ttgtagtcat ttattattct tcaaagaaaa atggtggggc gaattttttc
     7261 agttcttcaa agcacttttg agcagtatct gcatcttcac agatgataag acagacatca
     7321 ttaccacaaa gggtagcgat agcgtcaggg aagctcaaag tatcaatgat agaaccaaag
     7381 gattgagcca gtccaggaag ggtttttagt aggacttggt gttgaactgg gcgcatccag
     7441 acaagggcgt cttccatgta gagttcgaga cgtttttccc attttgagat ggaaccattg
     7501 ttaagaacat aataagcgct atcttcttcg cggacttttg ataggttcat atttttgatg
     7561 tcgcgtgaga gggttgcctg ggttacttga atgtcgttct cagcaagaag ggcttgcaac
     7621 tcagcctgtg tatgaatctt gttttttgtg ataagagcgc gtataagttg gtggcggtgt
     7681 tctgatttat tcataataat gtaactcctt ttagcaaggt aaggtaagca tggactgagc
     7741 gaggtcgaca gtcaagtggt agtctgtatt gtcacggatg gtgatttcaa agtcagtagt
     7801 atagaggact aaacggagag tgtctccttc ttttagcttg taaatagttg gctgcagttc
     7861 aaattgaacg tccatccatt catctgcagt aatatcctct actaacagta aatcatttct
     7921 attttgtaaa ttaaggtaac cttttgtcac gactcgttgt gcctctggtc taaatggcaa
     7981 ttcacagaga ttttccaaca tgtgatagcg accgttgtca atggttctag cacttaaaat
     8041 agctggataa ggttgtaggt atttcttttg cccaaattct agcagttggg cagataagag
     8101 ccccttgttt gtactggatt tgatacgaag attgagctga gcgcgaccgt ttaggtggag
     8161 atctttagtc acaggaaggt taatagtaat ctgattggct ttcccttgat agagctctgt
     8221 attgaaggtt tggtatgtct taccatagcg ctcaaaatcc ttatctgggt actggttttg
     8281 aatagcttgc tcttcttgac caagtgagaa ggtttcacag ttttcttgcc caccgaagtt
     8341 atcaagtgat aaccaagtct gtggagctgt attgtcctgc cagataacag taggaagttg
     8401 aaagtctgtt tcctgtccta gtaatttctt ggtcaataag gcatttatgg actcacggaa
     8461 gtcaattgat tgccaattgt tcatgtaaac atgggcacca ttatggaaaa agagatgctt
     8521 gtgtatatga gtaggaagag catggaacat ctggtaaaca tgaagtggtt tgacattcca
     8581 atcctgagaa ccatgagtaa agacaacctc tgcctttact ttatgggcat tgagcagata
     8641 attgcggtca tgccaaaact gattgtagtc cccagttttt cggtctagct gagctttcac
     8701 tttttctaag tcagcttggt gagcttcatt gccacggata tagtcgccag ctaagagatt
     8761 acgagaatag gttaactcag caagggagtc aaagtcctca cctggataac cacctgggct
     8821 agtcaccaga ccgttttcac ggtagtagtt gtaccatgat gaaattcctg cctcggcaat
     8881 gataacttct aaaccatcga ctcctgtagt cgcaagacca ttggacatgg tacctagata
     8941 ggaaagtcct gttgtagcaa cttttccgtt tgaccaatca gccttgactt gacgctggcg
     9001 cgtgtgatca gtaaaggcac ggcaacggcc gttaagccaa tcgatgacat ttttataagc
     9061 ctcgatttgc tggtagtctc cattagtcat gaaacctgtc gagtctttgg taccaacacc
     9121 tgagacatag agattggcaa agcctctcgg aaggaagtag tcgtttagtg tatagctaga
     9181 gttgatgtga gttagctttt cctcagcctc tgctataagc tcagctttac cttggggttg
     9241 gacgagattt agttgaggtt tctctagctc aatcttgtga ggaagtttaa cctcaagctc
     9301 gccctccatc ttgtagagag ccttgtcact agccttgtca ttggttccct gatgataagg
     9361 gctggctgtc atgatggcag ggatttttcc atcaaaacga gggcgaataa tgctaacctt
     9421 tactaggtct gatagccctt tttggtcagt atcgacacga gactcaacgt aaacgacttc
     9481 acgaatgaca tcctggttag aaaaagtagc caaactcttg ccgttaaagt agtggtagtc
     9541 attatcctcc ggaataagac catcactaac aagttggtcg ataagagtat ttcctttttt
     9601 ggtgcgagta ttgagtaact gatagagatt ttcaatcaag tcaccatata taatgggaaa
     9661 tccagtttct ttacgaaaaa cgtcactatc ttcgaagtca accaaataag aaaagcctaa
     9721 aagttgaaaa gcaacagtat aaaaaatatc tgctgtcagt tcatcttctg attgaaaaaa
     9781 tgtcagcagg tctgtttttt tatcagctgc taggatagaa agtgggtagt tggtgtcttg
     9841 ataagtgaaa aagaaacgac gtaaaaaggt ttcaagtgag tctttgtgat tggctgtatt
     9901 ttgtaaatca aagccacatt tttttagttc agataagaca ttttcttttg gaaaattgat
     9961 ataactatat tgattaaaac gcatagaacc tccatataga atgacagtta aggttattat
    10021 atcaaaaaaa aagcagaaag ggaattgtta acttcaaaag gaaataatcc aataaaaatg
    10081 aataaagtac taaattcaat atagagaaca gagtaacaat aagaataaat agatagggta
    10141 taaaagttct aggagattta tattatatgc tttctatttt tatatacaat atagtataaa
    10201 tataaaaatg atgacaaaaa tacaaatgaa tagaaaataa attagtaagc tgatgaaatt
    10261 tttctcaaga gaagccattt ataggtgaaa atggtataat atagtgagaa ggatagagga
    10321 gaagtgtaaa ttgatcgcac aactagatac aaaaacagtc tatagtttta tggaaagcgt
    10381 catttcgatc gaaaagtatg tgagagcagc taaagaatac ggctacactc atttggctat
    10441 gatggatatt gacaatcttt atggcgcttt cgactttcta gagattacaa aaaaatacgg
    10501 cattcatcct ttgctagggc ttgaaatgac agtgtttgta gatgatcagg aagtgaattt
    10561 gcgcttttta gctctatcta gtgtgggcta tcagcagttg atgaagcttt cgacagccaa
    10621 gatgcagggg gagaaaactt ggtcagtcct gtcccagtac ctggaggata tcgcggtcat
    10681 tgtgtcttat tttgatagag ttgagtcgtt agaactaggc tgtgattact atataggggt
    10741 ttatccagaa acactagcaa gcgaatttca tcatcctatc ttacctcttt atcgggtcaa
    10801 cgcttttgaa agcagggata gagaagttct tcaagtttta acagcgatta aagaaaatct
    10861 accgctcaga gaagttccct tgcgttcgag acaagatgtc tttatatcag caagttcttt
    10921 agagaaacta ttccaagagc gttttccgca agctttggac aatttagaaa agcttatttc
    10981 aggcatttct tacgacttgg atactagtct gaaactgcct cgttttaatc cagctagacc
    11041 agcagtagag gagttgagag agcgtgctga actggggctt gttcagaagg ggttgactag
    11101 taaagaatat caagatagac tagaccaaga attgtctgtt attcatgata tgggctttga
    11161 tgattatttc ttggttgttt gggatttgtt gcgttttgga cgatcgaatg gctattatat
    11221 gggaatggga aggggttctg cagtaggcag tttggtttct tatgccttag acatcacggg
    11281 gattgaccca gtagagaaaa atctgatttt tgaacgcttt cttaatcgtg aacgctatac
    11341 catgcctgat attgatattg atatcccaga tatttatcgt ccagatttta tcagatatgt
    11401 tggtaataaa tatggtagta aacatgcggc acaaatcgtt actttttcaa cctttggagc
    11461 caagcaagct cttcgagatg tcttgaaacg ctttggtgtg ccagagtatg aattatctgc
    11521 aattactaag aaaatcagtt ttcgtgacaa tcttaagtcg gcctatgagg gcaatctcca
    11581 gtttcgtcag caaatcaata gtaagttaga ataccaaaaa gcttttgaga ttgcttgcaa
    11641 gatagagggc tatccaaggc aaacctctgt ccatgcggct ggtgttgtaa ttagtgacca
    11701 agatttaacc aactacattc ctctaaagta tggtgatgaa attccactga ctcagtatga
    11761 tgctcatgga gttgaggcta gcggactttt gaagatggac tttctgggac tacgaaattt
    11821 gacctttgtc cagaagatgc aagagttgct tgctgaaaca gaaggtattc atctgaaaat
    11881 tgaagaaatc gatttagaag acaaagaaac gttagcttta tttgcctctg gtaatacaaa
    11941 aggtatcttt caatttgagc aaccaggtgc cattcgtctg cttaagcgtg tgcaaccagt
    12001 ctgttttgaa gatgtcgtcg cgactacttc tctaaatcga ccaggtgcaa gtgactacat
    12061 caataatttt gtggcaagga agcatgggca ggaagaagtg actgttctag attcagctct
    12121 ggaggatatt ttggctccaa cttatggcat tatgctctat caggagcagg ttatgcaggt
    12181 tgctcagcga tttgctggat ttagtcttgg gaaggccgat attttgcgtc gagctatggg
    12241 taaaaaggat gcctctgcta tgcatgagat gagggcttcc tttattcaag gctccataga
    12301 agcaggccat actgcggaaa aagcagagca ggtttttgat gttatggaga agtttgcagg
    12361 ttatggattt aatagatctc atgcctacgc ctactcagcc ttggccttcc agttggctta
    12421 tttcaaaacg cattatccag ccatttttta tcaggtcatg ttaaattatt ccaacagtga
    12481 ttacttaata gatgcacttg aagcaggttt tgaagtagcc tctctatcca tcaatactat
    12541 tccctatcac gataaaattg ccaacaagtc tatctatata ggtttgaaat cgattaaggg
    12601 gctcagcaag gacttggcgc tttggattat tgaacataga ccttattcta acattgaaga
    12661 ttttatagct aaattacctg agaattatct gaaacttcct ctgctagaac ctttggtaaa
    12721 agttggtctt ttcgattcat ttgaaaaaaa tcgtcaaaaa gtatttaata acttagctaa
    12781 tctatttgaa tttgtgaaag agttgggaag tttgtttgga gatgctattt atagttggca
    12841 ggaatcggaa gattggacgg aacaagaaaa attttatatg gaacaagagc ttttagggat
    12901 aggtgtcagc aaacatccac tacaagctat tgcaagtaag gctatttacc cgattacccc
    12961 aatcggaaat ttgtcagaaa atagctatgc tattattttg gttgaagttc agaaaataaa
    13021 agtgattcgt accaaaaagg gtgaaaatat ggccttctta caggcagatg atagtaagaa
    13081 aaaattggat gtcactctct tttcagactt atatcgtcag gttggacagg aaataaaaga
    13141 gggagccttc tactatgtaa aaggaaaaat acaatcacgt gatggccgtc tgcaaatgat
    13201 tgcacaagaa ataagagaag cagttgctga acgcttttgg atacaggtga aaaatcatga
    13261 atcggatcaa gaaatttcac gcattttaga acaatttaaa ggcccaatcc cagtcatcat
    13321 ccggtatgaa gaggaacaga aaaccatcgt ttctccccat cattttgtag ctaaatccaa
    13381 tgaattagag gagaaattga atgaaatcgt tatgaaaacg atttatcgct aaaaatacgg
    13441 aaaatagaag aattttaaaa tcaaatgtga tataatcaag aagaatgtta aaagaaaaag
    13501 gagcataaac caatatgaaa cgtattgctg ttttgactag tggcggagac gcacctggta
    13561 tgaacgctgc catccgtgca gttgttcgtc aagcaatttc agaaggaatg gaagtgtttg
    13621 gtatctatga cggatatgct ggtatggttg ccggtgaaat tcatccccta gatgcagctt
    13681 cagtagggga catcatttct cgtggtggta cttttcttca ctcagctcgt tatccagagt
    13741 tcgctcaact tgaagggcaa cttaaaggga ttgagcaatt gaaaaaacac ggaattgaag
    13801 gtgtagttgt tatcggtggt gacggatctt accacggcgc tatgcgtttg actgaacatg
    13861 gcttcccagc tattggtctt ccaggtacaa tcgataacga tatcgttggt actgacttta
    13921 caatcggttt tgacacagcg gttactactg ccatggacgc tatcgataag attcgtgata
    13981 catcatcaag tcaccgtcgt acttttgtaa tcgaagttat gggacgtaac gctggtgata
    14041 tcgctctttg ggctggtatt gcaactggtg ctgatgaaat catcatccct gaagcaggct
    14101 tcaagatgga agatatcgta gcaagcatca aagctggtta tgaatgtggt aaaaaacaca
    14161 atatcatcgt cttagctgaa ggtgtgatgt cagcggctga atttggtcaa aaacttaaag
    14221 aagctggaga tacaagcgac cttcgtgtaa cagaacttgg acatattcaa cgtggtggtt
    14281 ctccaactgc gcgtgaccgt gttttggcgt cacgtatggg tgcacatgct gttaaacttc
    14341 ttaaagaagg tatcggtggt gttgcggttg gtattcgtaa cgaaaaaatg gttgaaaatc
    14401 caattcttgg tactgcagaa gaaggggcat tgtttagcct tactgcagaa ggtaagattg
    14461 tggttaacaa cccgcacaaa gccgatattg agctatctag cttgaataag agcttgtcat
    14521 aatttacaat ttagttaata agaccaaaaa ggtcatatat ataaaggagt cacaaaaatc
    14581 atgaacaaac gtgtaaagat cgttgcaact ttgggtcctg cggtagaaat ccgtggtggt
    14641 aaaaaattcg gtgaggacgg atactggggt gaaaaacttg atgttgaagc ttcagctaaa
    14701 aacattgcta aattgattga agctggtgct aacacattcc gattcaactt ctcacacggc
    14761 gaccaccaag aacaaggtga gcgtatggca actgttaaac ttgcggaaaa aattgcaggt
    14821 aaaaaagttg gtttccttct tgatacaaaa ggacctgaaa tccgtacaga attgttcgaa
    14881 ggtgaagcta aagaatattc atacaaaact ggtgaaaaaa ttcgtgttgc aactaaacaa
    14941 ggaatcaaat caactcgtga agtgattgcg ttgaacgttg ctggtgctct tgatatctat
    15001 gatgatgttg aagttggtcg tcaagttttg gttgacgatg gtaaacttgg tcttcgtgtg
    15061 gttgctaaag atgatgcaac tcgtgaattt gaagttgaag ttgaaaacga tggtatcatc
    15121 gctaaacaaa aaggtgtgaa catccctaac actaaaattc ctttcccagc tcttgctgaa
    15181 cgcgataacg acgatatccg tttcggtctt gaacaaggta tcaacttcat cgcaatttca
    15241 ttcgtacgta ctgcaaaaga tgtgaacgaa gttcgtgcaa tctgtgaaga aactggaaac
    15301 ggacatgttc aattgttcgc taaaatcgaa aaccaacaag gtatcgataa cttagatgaa
    15361 atcatcgaag cagctgatgg tattatgatt gctcgtggtg atatgggtat cgaagtaccg
    15421 ttcgaaatgg ttccagttta tcaaaaaatg attatcaaga aagtcaatgc tgcaggtaaa
    15481 gttgttatca ctgcaacaaa catgcttgaa acaatgactg aaaaaccacg tgcaactcgt
    15541 tcagaagtat cagacgtatt caacgctgtt atcgacggaa ctgacgctac aatgttgtca
    15601 ggcgagtctg caaacggtaa atacccactc gagtcagtaa ctacaatggc tacaatcgac
    15661 aagaacgctc aagctcttct taatgaatac ggacgtcttg attcagattc atttgagcgt
    15721 aactctaaga cagaagtaat ggcttctgct gttaaagatg ctactagctc aatggatatc
    15781 aaattggttg taactcttac taagacaggt catactgcac gtttgatttc taaataccgt
    15841 ccaaatgctg acatcttagc attgacattt gacgaattga cagaacgtgg cttgatgttg
    15901 aactggggtg ttatcccaat gttgacagat gctccatctt caactgacga tatgttcgaa
    15961 atcgctgaac gtaaagcggt agaagcaggt ctcgttgagt caggcgatga tatcgttatc
    16021 gttgctggtg tgccagtagg agaagctgtt cgcacaaaca caatgcgtat ccgcacagta
    16081 cgttaagaaa aatataaaaa cctatcatat ccagctttct agcctgtatg atgggctctt
    16141 tttttgtcca gggggcaaaa agggggcaaa actttcataa tggattgata ctcttcgaaa
    16201 atcaaattca aaccacgtca gcgtcgcctt accgtatata tgttactgac ttcgtcagtt
    16261 ctatctacaa cctcaaagca gtgctttgag caacctgcgg ctagcttcct agtttgctct
    16321 ttgattttca ttgagtatga aataagatat gcataaattg attagaaagt caaatgaatt
    16381 tctacaaatg ttttagcaat cgcaatctac ttgtctagat tcgatctgat atattttcga
    16441 tttaatgata tggtatttaa aacctccaaa gtagcttgct ccattctttt acctacgtga
    16501 gtctagatgt tatttactgt tttagcgttt ttgtgttcta ctctaaccat tatagcattc
    16561 ttctcagcta gtgtactaag gagtgtgtgc ctgaaaatat gggaactaag gggctggttt
    16621 atcggtttct ctagtttagt atttgccttt tgcaaagtga tcttaaatgc ctttctctaa
    16681 atttacatat cactattgtt taacaaaatc taatctattt taggtcactt attctttttt
    16741 tgaaatgtag aatgaacttt ttcaaagttt ttcgaatctt ttaaaatctg tttgttttat
    16801 atcgccattc tccccctttt ttaattctcc ctatatagcc tgacaacttt tccgatggta
    16861 cgaatatggt tgctttcgtc taggtggatg tcggagtatt cgggattgag tttttttgag
    16921 gtagccttgg cggagtttct tgacatagtt agtgccgtct acttggaaga tgccgatggt
    16981 attatagtca atctgtgggg tattcttgat aaataggtag tcgctgtttc ttatctttgg
    17041 ctccatggac ttgctgacga cataagcgat tgggtcgtag tcgtctggga taatggaaac
    17101 tccataacta aatcgtcgtc ctgcatcaag cggctacctg cagagataaa ctacctaaca
    17161 cgagagtaag tagtctgtct gtagtcgtcc agtctgatga tttttacgat acttcgtttt
    17221 tctgatcata cagttgcctc tcggcatagg tcagaacttt accttgtctg ggtggtgccc
    17281 gttggtcgta gatagattgg atatcgctag gagaatcctt ttgaactgga ggaaagaggg
    17341 catcaatcaa gctactgaat actttaacta agtcaaatat agtatttttc ttagtagacc
    17401 taaccctttt ttcataattt ctaatggtgt ttttacttat acctatctta gtacccaatt
    17461 cttattgagt ccaaccatta ctagtctata ttgttttata gttgattgag tttggaatag
    17521 tacgctgtag ctgctaaaac atttctagga attaatttgc ctttcctaat agagttgttc
    17581 atatcttatt tcaatctact atatttttca cctctaacaa tcgcaatctc ttctttatcc
    17641 atgaacgaaa acgctttcta tctttgtaag taaagcatca cacgaaatcc acgaaaatga
    17701 aaacctttgt tgtgttttcg taaaaaattt gttgacagag cacgaaacgc ctactataat
    17761 taaatcaagt ttaaggaaat aacaaaaaaa caaatcggag ggaaagacga tgaacacatt
    17821 aaatgagaaa gtaatcaata tctgtaaagc agtagttaaa gaaactttaa tccaagacat
    17881 ttaggagaaa gaaatgaaga aatcaagaaa attagccaca ttaggaatct gttcagcctt
    17941 gtttttaggc ttggctgctt gtcaacaaca acatgctact tctgagggga cgaatcaaag
    18001 gcaaagcagt tcagcgaaag ttccatggaa agcttcatac accaacctaa acaaccaggt
    18061 aagtacagaa gaggtcaaat ctctcttatc agctcacttg gatccaaata gtgttgatgc
    18121 attttttaat ctcgttaatg actataatac cattgtcggc tcaactggct tatcaggaga
    18181 tttcacttcc tttactcaca ccgaatacga tgttgagaaa atcagtcatc tctggaatca
    18241 aaagaagggc gatttcgttg ggaccaactg ccgtatcaat agttattgtc ttttgaaaaa
    18301 ttcagtcacc attccaaagc ttgaaaagaa tgaccagttg cttttcctag ataatgatgc
    18361 gattgataaa ggaaaggtct ttgattcaca agataaggaa gagtttgata ttctattttc
    18421 gagagttcca actgaggcaa ctacagatgt caaggttcac gctgaaaaga tggaaacatt
    18481 cttctcacaa tttcaattca atgaaaaagc tcgaatgctg tctgtagtct tgcacgacaa
    18541 tctggatggc gagtatctgt ttgtaggcca cgttggggtc ttagtacctg ctgatgacgg
    18601 tttcttattt gtagagaaat tgactttcga agagccctac caagcgatta aatttgctag
    18661 taaggaagat tgctacaagt atttaggcac caagtatgcg gattatacag gcgagggact
    18721 ggctaagcct tttatcatgg ataatgataa gtgggttaaa ctttaatagt gttatgatat
    18781 gacagtaatc ttaggatttt tatttctatt tttgatgagt tggtgggtta tttcaatcgt
    18841 taatagccag aaaccacgca aaaatgaaac atttattggc tatatccaaa gatacgatat
    18901 tgatgggaat ggctatcaat cattaccgtg tcctcagaac tgagaggagt tcttgaaatc
    18961 gtaaaactac tttgaacaag agttacttca acccattggc tccgacggat taagttgctt
    19021 tcgtgaacac caaaatcagc cgcaatttct tcataagtgc ggtattctcg cacatattga
    19081 agagtggcca taagaaggtc ttctaggctt aatttaggtt ttcgtccccc ttttgtgtgt
    19141 ttaagttgat aagcagtttt taatacagct aacatctctt caaaagtggt gcgctgaaca
    19201 ccaacaagac atttaaatcg tgcatcagtt agttgcttac ttgcttcata attcatagaa
    19261 ctactatacc atattttgtt tcgcaggaag tctaatgcta aaatcttatc agtgagaaga
    19321 tttcttaaag tttattcttt gtagtttcat ctgtattagt acataattta acttagagaa
    19381 aataggagga ctaatcgaat ggaattaaaa gattttacag aaaaagaaca ggaaatgatt
    19441 aagaaaaggc ttacaatgtc taatattagt gacaaagaaa ctactgagaa gattctggcg
    19501 ctagtaccac aagacttgat taagcgaatc ccgttttttg tcagaaaaca tgctacaaca
    19561 cgtacgatta aacgcatttc aattgaacac cctgaactct acgctgtagc tcaaacaagt
    19621 ggtgagattc cagaaaaaaa aacgcgaaga attgcgtcag attatcacaa ctatctttga
    19681 acaaaagatg aataagcata gtattaagta gagaatgaaa aaatatttta ttggcggttt
    19741 gggaagcaat gcctatcata gcaaggattt tctttaagaa ctagattcgc aggtctattt
    19801 tctaaatcca tatgaaaagc atcttcgaga tgaaacagaa ttgaaatcat ggtttaaaaa
    19861 tgagattgta gaggaagaat ctatctgtct gataggtcat tctattggag gcgatttagc
    19921 tcgttatttc gcatcggaat ttgaagaagt aaagaaactg attcttttgg atggtggcta
    19981 tctagattta gataagattt tacctttgga tacagagtta gaggaaacta aaaattatat
    20041 caaatctcaa attatttcgg acttagatgt tcttacttct aaagaaaaat ctgaagcaaa
    20101 gcattggtca gaaaatatgg agaaagctgt aagacagtcc tatcactgga atgttgagta
    20161 taatagatat gagttggcta taaattatga aaatatagaa gcgatactcc gcctacggag
    20221 aaaaatacaa gcttttaaga gagaagtggg agataccttg tttattagtc ctcgctatcc
    20281 taatgaagct acatggagag aggaagccct aaaagaattg ccagactatt ttgatactat
    20341 ttttttagaa aactttggcc atgagcttta tactcaagca cctaaagaaa tcgctagtct
    20401 aatgaatgag tggctcgctt attttctatg agctacttgt attgctggaa atggtataag
    20461 atgaaaatct acaagtcact aattttcata taaccaaaaa acgaacaggc tctttttctg
    20521 ttattcagaa gagaacttgt tcgtttttat cttgattttc ttaaaaagct ctatatacat
    20581 agggattttc tggtttatcg actttggtaa agctgtcgat ttccaaggtt ggaaggtttt
    20641 gtttgagttc tttatggtag tgattgacca gttttccttt ggctgaaatc caagtgttgt
    20701 tttcatactg ccgggtattg cccttggtca gcaatccata gacaccagaa tctgcgatac
    20761 agtggataat gccgaatcgg aacagaaatt gactattggc atgactgggg tcgttataga
    20821 caaagcctgt aaactggatt gtcttgccct caaactcatc tggatagtcg tagatagcct
    20881 ccatgacttc catatagttt tcattagtga tctgaatgct gtcttgggat aagtatttat
    20941 ccgccgccgt tcgcatttcc ttttcatagg ctgattttga aaaataagaa ctagtatctg
    21001 gtttcaaata ttggcttgta gtcccttcac ttgtctgaat agccagattc gttccttccg
    21061 atagagggaa atgatagcct ttagctgaaa cagtctgaga atccaagcta acagttggga
    21121 aagttaagcc gatgacaagt ggaatagcca gaagagaaat actcgtcatc ttggccaatc
    21181 ggctgttcag atgactgtgg gttttgactt gcttcatcca gatatacaat tgaacgatag
    21241 ccaagataaa agaaagcacc atggagatat aggccagata ggaatagtgc atgttgatgt
    21301 actggtttag tttgcccgac agatggaggt aaatagtcag ttcaaaatag ccagctaaaa
    21361 ctaaaaatcg aatcatagga tgactccaat caagagagaa tagactaaga cgacaagagt
    21421 tacaattgtt atgaagtgac tgataaatcg tgctttcaag taatttttca tcatgagaat
    21481 atttttgata tccagcattg gaccaatgac gagaaaggcc agaactggtg ccaaaccgaa
    21541 actcgagaga agagaagcac ctataaaggc atccgcctca ctacagagcg aaagaagaaa
    21601 ggctaaaatc atcaagagca ggatggcaaa aagaggggtc gcactgatag aggtcagaat
    21661 ccgagtcgga acgtagacct gtattataga agcaaagagg cagccaaata ccaaataacg
    21721 ccccgtatca aaaaattcat caatggcctg cacaaagact tgaaaaactt tttttgcaga
    21781 actcaagtaa gaaaaatcat gctcatgaca agccagacga ttttctttct gaatcggttc
    21841 ttgccagaaa aatcctagaa aaattcctag tattacagcc acaagaatgg aacccagagc
    21901 tcgtaatagg gcgacatgga aggagttgcc aaaggcagaa taggtcgcaa aaagaacaat
    21961 gggattgata acaggtgctg tcacaagaaa aggaacggcc gtgtaacttg gaaccttttt
    22021 ttccagaaaa cgattgatga tggggacgat tccacattca caagaaggga aaagtatacc
    22081 gacaaaggtc ccaaaaaaga ttctccccca acgatttcga gggagaaaat gataaacctt
    22141 gtcaggtgtg atataaactt caatcagccc tgagacaatg cttcctatca gaacgaaggg
    22201 aagggcttca atgataatgg agagaaaaat ggctccagtt tgaagtacac tagatgggag
    22261 ttgttgaaaa gcagtcatct agtttttctt ttctgctttg acttttttct ctttgtcatc
    22321 agggaaagta acttgtttca aatcagggag tttagcaaac tcttcaaaca tcttgtccaa
    22381 gtcgtctcgt tttgtaaatt tgacagccat aggtgtacct cgattctaaa ttctacctct
    22441 attatactat tattttgcgg aaaagggagt tttttaattt gttttcgata gttgatactc
    22501 ttcgaaaatc tcttcaaacc acgtcagctt cgccttaccg tagtacggtt
//
LOCUS       DAVLBE010000028        22406 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.028, whole genome shotgun sequence.
ACCESSION   DAVLBE010000028 DAVLBE010000000
VERSION     DAVLBE010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22406)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22406)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22406
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.028"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            1..160
                     /locus_tag="VXB91_001215"
                     /pseudo
     CDS             1..160
                     /locus_tag="VXB91_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            555..941
                     /locus_tag="VXB91_001216"
     CDS             555..941
                     /locus_tag="VXB91_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetyltransferase"
                     /protein_id="HEV0470671.1"
                     /translation="MFAWFLFYEVGSKKDYVSYINPGLWGIAFIVCVLVAFAIFPKME
                     KNFPKTFLYFTKYGKDSLGIYILHAPICSMIRILMLKVGINSVFLHVVVGIVLGWYLS
                     ILATYILKKIPFLNIVLLPQKYIKLK"
     gene            1119..3101
                     /locus_tag="VXB91_001217"
     CDS             1119..3101
                     /locus_tag="VXB91_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0470672.1"
                     /translation="MKSSKLFALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETDP
                     DNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKDA
                     KWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDAYVKGEIKDFSQVG
                     IKVLDEQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGP
                     YLLKSIVTKSSVEFAKNPNYWDKDNVHIDKVKLSFWDGQDTSKPAENFKDGSLTAARL
                     YPTSASFAELEKSMKDNIVYTQQDSITYLVGTNIDRQSYKYTSKTSDEQKASTKKALL
                     NKDFRQAIAFGFDRTAYASQLNGQTGASKILRNLFVPPTFVQADGKNFGDMVKEKLVT
                     YGDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVTFPIHLDMPVDQTATTKVQ
                     RVQSMKQSLEATLGADNVIIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFA
                     DPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDEATDVAKRY
                     DKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPILYKYLELQ
                     DKAVTVDEYQKAQEKWMKEKEESNKKAQEDLAKHVK"
     gene            3402..8705
                     /locus_tag="VXB91_001218"
     CDS             3402..8705
                     /locus_tag="VXB91_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEV0470673.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSPVLADSVQSG
                     STANLPADLATALATAKENDERDFEAPKVGEDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKPAAAKPETPKTVTPEWQTVEKKEQQGTVTIREEKGVRYNQLSSTAQNDNAG
                     KQALFEKKGLTVDANGNATVDLTFKEDSEKGKSRFGVFLKFKDTNNNVFVGYDKDGWF
                     WEYKSPTTSTWYRGSRVAAPETGSTNRLSITLKSDGQLNASNNDVNLFDTVTLPAAVN
                     DHLKNEKKILLKAGSYDDERTVVSVKTDNQEGVKTEDTPAEKETGPEVDDSKVTYDTI
                     QSKVLKAVIDQAFPRVKEYSLNGHTLPGQVQQFNQVFINNHRITPEVTYKKINETTAE
                     YLMKIRDDAHLINAEITVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDERKLLSSISF
                     LGNALVSVSSDQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVSTDKLA
                     AGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFPEYTKE
                     LPSAKVVITEDANADKKVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFGSQAQN
                     PFLMTLDGIKKINLHTDGLGQGVLLKGYGSEGHDSGHLNYADIGKRIGGVEDFKTLIE
                     KAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDAAYDLA
                     HGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRFAIEWG
                     HGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAANYPLL
                     GGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDNGSTYK
                     WTPEMRVELVDADNNKVVVTRKSNDVNSPQYRERTVTLNGRVIQDGSAYLTPWNWDAN
                     GKKLSTDKEKMYYFNTQAGATTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVKDGKIT
                     LDLLANQPYVLYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEIVKSQG
                     ANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKASVTVNTGEKEVTTYT
                     NKSLALNYVKAYAHNTRRNNATVDDTSYFQNMYAFFTTGSDVSNVTLTLSREAGDQAT
                     YFDEIRTFENNSSMYGDKHDTGKGTFKQDFENVAQGIFPFVVGGVEGVEDNRTHLSEK
                     HNPYTQRGWNGKKVDDVIEGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYRVTFEY
                     EAGSDNTYAFVVGKGEFQSGRRGTQASNLEMHELPNTWTDSKKAKKATFLVTGAETGD
                     TWVGIYSTGNASNTRGDSGGNANFRGYNDFMMDNLQIEEITLTGKMLTENALKNYLPT
                     VAMTNYTKESMDALKEAVFNLSQADDDISVEEARAEIAKIEALKNALVQKKTALVADD
                     FASLTAPAQAQEGLANAFDGNVSSLWHTSWNGGDVGKPATMVLKEPTEITGLRYVPRG
                     SGSNGNLRDVKLVVTDESGKEHTFTATDWPDNNKPKDIDFGKTIKAKKIVLTGTKTYG
                     DGGDKYQSAAELIFTRPQVAETPLDLSGYEAALAKAQKLTDKDNQEEVASVQASMKYA
                     TDNHLLTERMVEYFADYLNQLKDSATKPDAPTVEKPEFKLSSLVSNQGKTPDYKQEID
                     RPETPEQILPATGESQSDTALFLASVSLALSALFVVKTKKD"
     gene            complement(8872..11031)
                     /locus_tag="VXB91_001219"
     CDS             complement(8872..11031)
                     /locus_tag="VXB91_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HEV0470674.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     TIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEEETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYVAYPDDELQVASTIV
                     DVSNGKVIAQLGARHQSSNVSFGINQAVETNRDWGSTMKPITDYAPALEYGIYDSTAT
                     IVHDEPYNYPGTNTPVYNWDRGYFGNITLQYALQQSRNVPAVETLNKVGLNRAKTFLN
                     GLGIDYPSIHYSNAISSNTTESDKKYGASSEKMAAAYAAFANGGTYYKPMYIHKVVFS
                     DGSEKEFSNVGTRAMKETTAYMMTDMMKTVLSYGTGRNAYLAWLPQAGKTGTSNYTDE
                     EIENHIKTSQFVAPDELFAGYTRKYSMAVWTGYSNRLTPLVGNGLTVAAKVYRSMMTY
                     LSEGSNPEDWNIPEGLYRNGEFVFKNGARSTWNSPAPQQPPSTESSSSSSDSSTSQSS
                     STTPSTNNSTTTNPNNNTQQSNTTPDQQNQNPQPAQP"
     gene            complement(11028..11624)
                     /gene="recU"
                     /locus_tag="VXB91_001220"
     CDS             complement(11028..11624)
                     /gene="recU"
                     /locus_tag="VXB91_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HEV0470675.1"
                     /translation="MVNYPHKVSSQKRQTSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVQVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEVKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKGQK
                     SMPLEYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            11690..12217
                     /locus_tag="VXB91_001221"
     CDS             11690..12217
                     /locus_tag="VXB91_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HEV0470676.1"
                     /translation="MATALVLGYSAFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGSLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDELNELAENFSEN"
     gene            12287..12616
                     /gene="gpsB"
                     /locus_tag="VXB91_001222"
     CDS             12287..12616
                     /gene="gpsB"
                     /locus_tag="VXB91_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HEV0470677.1"
                     /translation="MASIIFSAKDIFEQEFGREVRGYNKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQ
                     ILDNSDF"
     gene            12637..13017
                     /gene="rnpB"
                     /locus_tag="VXB91_001223"
     ncRNA           12637..13017
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="VXB91_001223"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            13102..14259
                     /locus_tag="VXB91_001224"
     CDS             13102..14259
                     /locus_tag="VXB91_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HEV0470678.1"
                     /translation="MKKEFNLIATVAAGLEAVVGREMRELGYDCQVENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARFPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFEEWNWISDRLIQEVRTEAAKKVDRELELDIMGCDIDARMVEIAKANA
                     QVAGVAGDITFKQMRVQDLCSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            14272..15666
                     /gene="mapZ"
                     /locus_tag="VXB91_001225"
     CDS             14272..15666
                     /gene="mapZ"
                     /locus_tag="VXB91_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HEV0470679.1"
                     /translation="MSKKRRNRHKKEGQEPQFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEEFVETQSLDDLIQEMREAVEKSEASSEEV
                     PSSEDILLPLPLDDEEQGLDPLLLDDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTANQSDVDDFNTLYDAFYTDSN
                     KTALKNSQFDKLSQLKTLLDKLEGSREHTLAKSKYDSLVTQIKAIQDVNAQFEKPAIV
                     DGVLDTNAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSSSQTSSSSSS
                     QASSNTTSEPKPSSSNETRSSRSEVNMGLSSAGVAVQRSASRVAYNQSAIDDSNNSAW
                     DFADGVLEQILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGY
                     FVGNGAGHADDLDY"
     gene            15742..17166
                     /gene="gndA"
                     /locus_tag="VXB91_001226"
     CDS             15742..17166
                     /gene="gndA"
                     /locus_tag="VXB91_001226"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HEV0470680.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPYLDKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVADVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSRKDDEGQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVHASKVLPKPAAFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            17178..17867
                     /locus_tag="VXB91_001227"
     CDS             17178..17867
                     /locus_tag="VXB91_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0470681.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLMLLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELEVVQRFAVSYIY
                     KPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGIGYTMQE"
     gene            17965..18987
                     /gene="cbpC"
                     /locus_tag="VXB91_001228"
     CDS             17965..18987
                     /gene="cbpC"
                     /locus_tag="VXB91_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HEV0470682.1"
                     /translation="MKLLKKMMQVLLAVFFFGLLATNTVFANTTGGRFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIPGTGYRDNLFDNQPVNEIGLQEKW
                     YYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWIYE
                     EGHWYYLNKLGNFGDDSYNPLPIGEVAKGWTQDFHVTIDIDRSKPAPWYYLDASGKML
                     TDWQKVNGKWYYFGSSGSMATGWKYVRGKWYYLDNKNGDMKTGWQYLGNKWYYLRSSG
                     AMVTGWYQDGSTWYYLDPSNGDMKIGWTKVNGKWYYLNSNGAMVTGSQTIDGKVYNFA
                     SSGEWI"
     gene            19005..20003
                     /gene="cbpJ"
                     /locus_tag="VXB91_001229"
     CDS             19005..20003
                     /gene="cbpJ"
                     /locus_tag="VXB91_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpJ"
                     /protein_id="HEV0470683.1"
                     /translation="MKILKKTMQVGLTVFFFGLLGTSTVFADDSEGWQFVQENGRTYY
                     KKGDLKETYWRVIDGKYYYFDSLSGEMVVGWQYIPFPSKGSTIGPYPNGIRLEGFPKS
                     EWYYFDKNGVLQEFVGWKTLEIKTKDSVGRKYGEKREDSEDKEEKRYYTNYYFNQNHS
                     LETGWLYDQSNWYYLAKTEINGENYLGGERRAGWINDDSTWYYLDPTTGIMQTGWQYL
                     GNKWYYLRSSGAMATGWYQEGTTWYYLDHPNGDMKTGWQNLGNKWYYLRSSGAMATGW
                     YQDGSTWYYLNAGNGDMKTGWFQVNGNWYYAYSSGALAVNTTVDGYSVNYNGEWVR"
     gene            complement(20121..21353)
                     /locus_tag="VXB91_001230"
     CDS             complement(20121..21353)
                     /locus_tag="VXB91_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV0470684.1"
                     /translation="MKLFWTNNIYRQLLLNSCFSSFGDSIFYLAIINYVAQYNFAPLA
                     ILLISISEMVPLLSQLFLGILGDFQENRVKHALWIAKIKILLYAILTVFLVLSPFSLV
                     SVIMIVIINLISDTLSYLSAYMMNALYISVIKDDLHDAMGFRQSLMRVVRIVANLAGA
                     FLINVISIQTISLINTLTFVIAFLGLYVIRHTLYEVEKRIEMSHTALSFKKYFQHLKQ
                     SLAVLLRLKDTVILLFLTTSMIAILDVSPRLIALRFIQQTLAQLSIGQLLALLSIIMS
                     CGAILGNMTSSNLFKNIRFTHLLVFCEISLLTLITSILCQAYIVIFMTSFISSTIIGI
                     LSPRLQAAVFAHIPSDKMGTVGSALSTVDILAPSLLSLLALSIASGVSVQLALIFLYL
                     ILIALIFCQWLVKFNTHN"
     gene            complement(21396..22358)
                     /locus_tag="VXB91_001231"
     CDS             complement(21396..22358)
                     /locus_tag="VXB91_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase"
                     /protein_id="HEV0470685.1"
                     /translation="MTSSTEFGNFVSNLSFQHGIAGLLFPLNKLYPPELDSKILSIIK
                     KAVTIRTTHTYEYQYSLLFGDAGYLWLLLHLFSISKNQYYLQLANVTAKKLIENYDTL
                     EEIDFALGKSGVLLSLIKYYQFTNDNTLKIFIHNSIGEIYHYFLQRDTAKESILDYSF
                     AHGYCGIAYALFAYSKVLEPSMFYNDLHTFHTELKKLLEKVTSNTENLGNLQLSWCKG
                     ISGIILYLCMYDCDGNKDIISKYQEFVFNHHLKMMTGYCHGITSLLQTTVYNQNKLLM
                     KKIQQVILACSERDDHGLLMFQGDSGKADLFDFGIGSMGYIGVY"
BASE COUNT         6977 a         3964 c         5000 g         6465 t
ORIGIN      
        1 tccacgtaaa tccagcaaac tcaagccgct aatagctgaa gataaagcct ataaccatgc
       61 actgtctaag gatagaagca aggttgagaa catccttgcc aaagtaaaaa cgtttaaaat
      121 gttttcaaca acctatcgaa atcatcgtaa acgcttcgga tattttaggc atactatata
      181 ttttttattc aattattcac ttttgtattc aaaaggttgc gggtgcctct gtccgagtac
      241 ccactatgat atttaaccta ttgaatatct ataaatttcc tctgggagtt tcatggtatc
      301 tatatacgtt atggtcgata ttgatagttt atggtttact atctgttgtt ttcaaaaatc
      361 gtaagtccct tttgttagtt agtgtttttg cctatatttt cacactattt attcaaactg
      421 atatttttat tgtgcaacgg acgttggttt gggggatttg tttctttctt ggcagtgtat
      481 tgagtgaaat tcactttgat aaaattaatt tgaaaaaatt tctttttttc tttgtgttat
      541 ttgattttat ttatatgttc gcttggttct tgttttatga agtagggtct aagaaggatt
      601 atgtaagcta tattaaccca ggtttgtggg ggattgcttt tattgtctgt gtattagttg
      661 cttttgcgat ttttcctaaa atggagaaaa attttcctaa aactttccta tatttcacta
      721 aatacgggaa agatagttta gggatctata ttcttcatgc accaatttgt agcatgattc
      781 ggattctaat gttgaaagtg ggaataaact cagtttttct tcacgttgtt gttgggattg
      841 tgctaggctg gtatttatcc atactagcaa cttatatatt gaaaaaaatt ccatttttga
      901 atattgtttt attaccacaa aagtatatta aattaaaata aattatttta gatttataat
      961 gtggctcttt gtcaactaac atctggagag gacaatcact gtcttctctt tttttgtctt
     1021 ttcagaatat accaaattaa cacaaaaatt ctgaaaattc tgttgacatc tttctgaaaa
     1081 gagtttataa tggagagaaa gttttaaagg agaaaatgat gaaaagttca aaactatttg
     1141 cccttgcggg cgtgacatta ttggcggcga ctactttagc tgcatgctct ggatcaggtt
     1201 caagcactaa aggtgagaag acattctcat acatttatga gacagaccct gataacctca
     1261 actatttgac aactgctaag gctgcgacag caaatattac cagtaacgtg gttgatggtt
     1321 tgctagaaaa tgatcgctac gggaactttg tgccgtctat ggctgaggat tggtctgtat
     1381 ccaaggatgg attgacttac acttatacta tccgtaagga tgcaaaatgg tatacttctg
     1441 aaggggaaga atacgcggca gtcaaagctc aagactttgt aacaggacta aaatatgctg
     1501 ctgataaaaa atcagatgct ctttaccttg ttcaagaatc aatcaaaggg ttggatgcct
     1561 atgtaaaagg ggaaatcaaa gatttctcac aagtaggaat taaggttctg gatgaacaga
     1621 cagttcagta cactttgaac aaaccagaaa gcttctggaa ttctaagaca accatgggtg
     1681 tgcttgcgcc agttaatgaa gagtttttga attcaaaagg ggatgatttt gccaaagcta
     1741 cggatccaag tagtctcttg tataacggtc cttatttgtt gaaatccatt gtgaccaaat
     1801 cttctgttga atttgcgaaa aatccgaact actgggataa ggacaatgtg catattgaca
     1861 aagttaaatt gtcattctgg gatggtcaag ataccagcaa acctgcagaa aactttaaag
     1921 atggtagcct tacagcagct cgtctctatc caacaagtgc aagtttcgca gagcttgaga
     1981 agagtatgaa ggacaatatt gtctatactc aacaagactc tattacgtat ctagttggta
     2041 caaatattga ccgtcagtcc tataaataca catctaagac cagcgacgaa caaaaggcat
     2101 cgactaaaaa ggctctctta aacaaggatt tccgtcaggc tattgccttt ggttttgatc
     2161 gtacagccta tgcctctcag ttgaatggac aaactggagc aagtaaaatc ttgcgtaatc
     2221 tctttgtgcc accaacattt gttcaagcag atggtaaaaa ctttggcgat atggtcaaag
     2281 agaaattggt cacttatggg gatgaatgga aggatgttaa tcttgcagat tctcaggatg
     2341 gtctttacaa tccagaaaaa gccaaggctg aatttgctaa agctaaatca gccttacaag
     2401 cagaaggtgt gacattccca attcatttgg atatgccagt tgaccagaca gcaactacaa
     2461 aagttcagcg cgtccaatct atgaaacaat ccttggaagc aactttagga gctgataatg
     2521 tcattattga tatccaacaa ctacaaaaag acgaagtaaa caatattaca tattttgctg
     2581 aaaatgctgc tggcgaagac tgggatttat cagataatgt cggttggggt ccagactttg
     2641 ccgatccatc aacttacctt gatatcatca aaccatctgt aggagaaagt actaaaacat
     2701 atttagggtt tgactcaggg gaagataatg tagctgctaa aaaagtaggt ctatatgact
     2761 acgaaaaatt ggttactgag gctggtgatg aggctacaga tgttgctaaa cgctatgata
     2821 aatacgctgc agcccaagct tggttgacag atagtgcttt gattattcca actacatctc
     2881 gtacagggcg cccaatcttg tctaagatgg taccatttac aataccattt gcattgtcag
     2941 gaaataaagg tacaagtgaa ccaatcttat ataaatactt ggaacttcaa gacaaggcag
     3001 tcactgtaga tgaataccaa aaagctcagg aaaaatggat gaaagaaaaa gaagagtcta
     3061 ataaaaaggc tcaagaagat ctcgcaaaac atgtgaaata actgttgcaa aatataagaa
     3121 aggatttagt atttctcttg aatgctgaat ccttttttac atttgtaaag aaagattcta
     3181 aatgtactga cccccaaaag ttggagcctc tttttgtcag aatagagaaa atttttgtta
     3241 attttacttg tttcctattg ctttatcagt tattatttgt tatattaaaa gtataattat
     3301 tttttattta tcagggttaa gcattgcact ttcagaggaa ggagtatttt ttaaaaagga
     3361 aatgtaaacg cttgcccaaa aatgaaagga tttagaagtt tatgaataaa ggattatttg
     3421 aaaaacgttg taaatatagt attcggaaat tttcattagg tgttgcttct gttatgattg
     3481 gagctgcatt ctttgggaca agtccggttc ttgcagatag cgtgcagtct ggttctacgg
     3541 cgaatttacc agctgattta gctactgctc ttgcaacagc aaaagagaat gatgagcgtg
     3601 attttgaagc gcctaaggtg ggagaagacc aaggttctcc agaagttaca gatggaccta
     3661 agacagaaga agaactatta gcacttgaaa aagaaaaacc ggctgaagaa aaaccaaaag
     3721 aggataaacc tgcagctgct aaacctgaaa cacctaagac ggtaacccct gaatggcaaa
     3781 cggtagagaa aaaagaacaa caaggaacag tcactatccg agaagaaaaa ggtgtccgct
     3841 acaaccaact atcctcaact gctcaaaatg ataacgcagg caaacaagcc ctgtttgaaa
     3901 agaagggctt gaccgttgat gccaatggaa atgcaactgt tgatttaacc ttcaaagaag
     3961 attctgaaaa gggcaaatca cgctttggtg tcttcttgaa atttaaagat accaataata
     4021 atgtttttgt cggttatgac aaggatggct ggttctggga gtataaatct ccaacaacta
     4081 gcacttggta tagaggtagt cgtgttgctg ctcctgaaac aggatcaaca aaccgtctct
     4141 ctatcactct caagtcagac ggtcagctaa atgccagcaa taacgatgtc aatctctttg
     4201 acacagtgac tctaccagct gcggtcaatg accatcttaa aaatgagaag aagattcttc
     4261 tcaaggcggg ctcttatgac gatgagcgaa cagttgttag cgttaaaacg gataaccaag
     4321 agggggtaaa aacagaggat acccctgctg aaaaagaaac aggtcctgaa gttgatgata
     4381 gcaaggtgac ttatgacacg attcagtcta aggtcctcaa agcagtgatt gaccaagcct
     4441 tccctcgtgt caaggaatac agcttgaatg gacatacttt gccaggacag gtgcaacagt
     4501 tcaaccaagt ctttatcaat aaccaccgaa tcacccctga agtcacttat aagaaaatca
     4561 atgagacaac agcagagtac ttgatgaaga ttcgcgatga tgctcactta atcaatgcgg
     4621 aaataacagt acgcttgcaa gttgtggaca atcaattgca ctttgatgtg accaagattg
     4681 tcaaccacaa tcaagtcact ccaggtcaaa agattgatga cgaaagaaaa ctactttctt
     4741 ctattagttt cctcggcaat gctttagtct ctgtttctag tgatcaaact ggtgctaagt
     4801 ttgatggggc aaccatgtca aacaatacgc atgtcagcgg agatgatcat atcgatgtaa
     4861 ccaatccaat gaaggatttg gctaagggtt acatgtatgg atttgtttct acagataagc
     4921 ttgctgctgg tgtttggagt aactctcaaa atagctatgg tggtggttcg aatgactgga
     4981 ctcgtttgac agcttataaa gaaacagtcg gaaatgccaa ctatgtagga atccatagct
     5041 ctgaatggca atgggaaaaa gcttataagg gcattgtttt cccagaatac acgaaggaac
     5101 ttccaagtgc taaggttgtt atcactgaag atgccaatgc agacaagaaa gttgattggc
     5161 aagatggtgc cattgcttat cgtagcatta tgaacaatcc tcaaggttgg gaaaaagtta
     5221 aggatatcac agcttaccgt atcgcgatga actttggttc tcaagcacaa aacccattcc
     5281 ttatgacctt ggatggtatc aagaaaatca atctccacac agatggtctt gggcaaggtg
     5341 ttctccttaa aggatatggt agcgaaggcc atgactctgg tcacttgaac tatgctgata
     5401 ttggtaagcg tatcggtggt gtcgaagact tcaagaccct aattgagaag gctaagaaat
     5461 atggagctca tctaggtatc cacgttaacg cttcagaaac ttatcctgag tctaaatact
     5521 tcaatgaaaa aattctccgt aagaatccag atggaagcta tagctatggt tggaactggc
     5581 tagatcaagg tatcaacatt gatgctgcct atgacctagc tcatggtcgt ttggcacgtt
     5641 gggaagattt gaagaaaaaa cttggtgacg gtctcgactt tatctatgtg gacgtttggg
     5701 gtaatggtca atcaggtgat aacggtgcct gggctaccca cgttcttgct aaagaaatta
     5761 acaaacaagg ctggcgcttt gcgatcgagt ggggccatgg tggtgagtac gactctacct
     5821 tccatcactg ggcagctgac ttgacctacg gtggctacac caataaaggt atcaacagtg
     5881 ccatcacccg ctttatccgt aaccaccaaa aagatgcttg ggttggggac tacagaagtt
     5941 atggtggtgc agccaactat ccactgctag gtggctacag catgaaagac tttgaaggct
     6001 ggcaaggaag aagtgactac aatggctatg taaccaactt atttgcccat gacgtcatga
     6061 ccaagtattt ccaacacttc actgtaagca aatgggaaaa tggtacaccg gtgactatga
     6121 ccgataacgg tagcacctat aaatggactc cagaaatgcg agtggaattg gtagatgctg
     6181 acaataataa agtagttgta actcgtaagt caaatgatgt caatagtcca caatatcgcg
     6241 aacgtacagt aacgctcaac ggacgtgtca tccaagatgg ttcagcttac ttgactcctt
     6301 ggaactggga tgcaaatggt aagaaacttt ctactgataa ggaaaagatg tactacttca
     6361 atacgcaggc cggtgcaaca acttggaccc ttccaagcga ttgggcaaag agcaaggttt
     6421 acctttacaa gctaactgac caaggtaaga cagaagagca agaactaact gtaaaagatg
     6481 gtaaaattac tctagatctt ctagcaaatc aaccatacgt tctctatcgt tcgaaacaaa
     6541 ccaatcctga aatgtcatgg agcgaaggca tgcacatcta tgaccaagga tttaacagtg
     6601 gtaccttgaa acattggacc atttcaggcg atgcttctaa ggcagaaatt gtcaagtctc
     6661 aaggggcaaa cgatatgctt cgtattcaag gaaacaaaga aaaagttagt ctcactcaga
     6721 aattaactgg cttgaaacca aataccaagt atgccgttta tgtcggtgtc gataaccgta
     6781 gtaatgccaa ggcgagcgtc actgtaaata ctggtgaaaa agaagtgact acttatacca
     6841 ataagtctct cgccctcaac tatgtaaaag cctacgccca caatacacgt cgtaacaatg
     6901 ctacagttga cgatacaagt tacttccaaa acatgtacgc cttctttaca actggatcgg
     6961 acgtatcaaa tgttactctg acattgagtc gtgaagctgg tgatcaagca acttactttg
     7021 atgaaattcg tacctttgaa aacaattcaa gcatgtacgg agacaagcat gatacaggta
     7081 aaggcacctt caagcaagac tttgaaaatg ttgctcaggg tatcttccca tttgtagtgg
     7141 gtggtgtcga aggtgttgaa gataaccgca ctcacttgtc tgaaaaacac aatccatata
     7201 cacaacgtgg ttggaatggt aagaaagtcg atgatgttat cgaaggaaat tggtcactca
     7261 agacaaatgg actagtgagc cgtcgtaact tggtttacca aaccatccca caaaacttcc
     7321 gttttgaagc aggtaagacc taccgtgtaa cctttgaata cgaagcagga tcagacaata
     7381 cctatgcttt tgtagtcggt aagggagaat tccagtcagg tcgtcgtggt actcaagcaa
     7441 gcaacttgga aatgcatgaa ttgccaaata cttggacaga ttctaagaaa gccaagaagg
     7501 caaccttcct tgtgacaggt gcagaaacag gcgatacttg ggtaggtatc tactcaactg
     7561 gaaatgcaag taatactcgt ggtgattctg gtggaaatgc caacttccgt ggttataacg
     7621 acttcatgat ggataatctt caaatcgaag aaattaccct aacaggtaag atgttgacag
     7681 aaaatgctct gaagaactac ttgccaacgg ttgccatgac taactacacc aaagagtcta
     7741 tggatgcttt gaaagaggcg gtctttaacc tcagtcaggc cgatgatgat atcagtgtgg
     7801 aagaagcgcg tgcagagatt gccaagattg aagctttgaa gaatgctttg gttcagaaga
     7861 aaacggcttt ggtagcagat gactttgcaa gtcttacagc tcctgctcag gctcaagaag
     7921 gtcttgcaaa tgcctttgat ggcaatgtgt ctagtctatg gcatacatct tggaatggtg
     7981 gagatgtagg caagcctgca accatggtct tgaaagaacc aactgaaatc actggacttc
     8041 gttatgttcc acgtggatca ggttcaaatg gtaacttgcg tgatgtgaaa cttgttgtga
     8101 cagatgagtc tggcaaggag cataccttta ctgcaactga ttggccagat aacaataagc
     8161 caaaagacat tgattttggt aagacaatta aggctaagaa aattgtcctt acaggtacta
     8221 agacttacgg agatggtggc gataaatacc aatctgcagc ggaacttatc tttactcgtc
     8281 cacaggtagc agaaacacct cttgacttgt caggctatga agcagctttg gctaaggctc
     8341 agaaattaac agacaaagac aatcaagagg aagtagctag cgttcaggca agcatgaaat
     8401 atgcgacgga taaccatctc ttgacggaaa gaatggtgga atactttgca gattatctca
     8461 accaattaaa agattctgct acgaaaccag atgctccaac tgtagagaaa cctgagttta
     8521 aacttagctc tttagtttcc aatcaaggta agacgccaga ttataagcaa gaaatagata
     8581 gaccagaaac acctgaacaa atcttgccag caacaggtga gagtcaatct gacacagccc
     8641 tcttcctagc aagtgttagt ctagccctat ctgctctctt tgtagtaaaa acgaagaaag
     8701 actagtattt agtaaaacct cttaacaaga ttacggaagc agtctctatc ttttccaatg
     8761 aggtttatag tacagaaaaa gcctgagaag atgtcttctc aggcttttgt taagcacata
     8821 aatacaatag tgctatgaca aaatcaccca gaaaaatctg ggtgataaat gttatggttg
     8881 tgctggttga ggattctgat tttgttgatc aggggttgta tttgattgtt gcgtattatt
     8941 gttaggattg gtagtcgtac tattatttgt gcttggagtg gttgagctag actgtgaagt
     9001 tgaactatct gatgatgagc ttgaactttc agttgatggg ggttgttgtg gagcaggtga
     9061 gttccacgta gaacgagcac catttttaaa tacgaattct ccatttctgt agagcccctc
     9121 tggtatattc caatcctctg gattgcttcc ttcagacaga taggtcatca tagagcggta
     9181 aactttggca gcgaccgtaa ggccattgcc tacaagtggt gtcagacggt tagaatagcc
     9241 tgtccataca gccattgaat atttacgcgt atagccagca aatagttcat caggtgctac
     9301 aaattgagag gtcttgatgt ggttttcaat ttcctcgtct gtatagttag aggttcctgt
     9361 tttaccagcc tgagggagcc aagcaagata ggcatttcgt ccagttccat aactcaagac
     9421 tgttttcatc atgtcggtca tcatataggc tgtcgtttcc ttcatggcac gagttccgac
     9481 attagagaac tctttttcac tcccatcact aaagacgact ttatggatat acattggttt
     9541 atagtaagtt ccaccatttg caaaggcagc gtaagcagca gccatctttt cactacttgc
     9601 tccatatttt ttgtctgatt cggttgtgtt acttgaaatg gcatttgagt agtgaatact
     9661 tgggtagtcg attccgagac catttaggaa agtcttggcg cggttgagtc cgaccttgtt
     9721 tagagtttcc acggctggga cgtttcgcga ttgttgcagg gcgtattgca aggtgatgtt
     9781 gccaaagtag cccctatccc agttataaac aggggtattt gtcccagggt agttataggg
     9841 ctcatcgtga acgatagtag cagttgaatc gtagataccg tactccaagg caggagcata
     9901 gtctgtgatc ggtttcatag ttgatcccca gtcgcggttt gtttctactg cttggttaat
     9961 tccgaaggaa acattacttg actgatggcg tgctcctagc tgggcaatga ctttaccgtt
    10021 agaaacatca acaatggtag aagcgacttg caattcatcg tctggatagg caacgtattc
    10081 gtctgtattg taaatatccc acagatgttt ttgagcttct tggtctacat ttgtgtagac
    10141 atccatccca gttgtgagca ggttatagcc tgtttcttct tcaacttgat tgatgacttc
    10201 cttgaggtaa ttatccatgt aagcagggta attacttgct gatttgagac tttgtagtcc
    10261 atcagtaatt ggtgtattga ctgctttctc atactgttca gcagagatgt agccttgatt
    10321 tttcatttca gataagacca agtttcggcg gtcttgggct gcttctggat gtgaataggg
    10381 gtcatattgg tttggtgcct gaggcattcc agccagcaag gctaactgag gtaaacttaa
    10441 attattgagg tctttaccat agtagttttg agctgctgtc tgcattccat agttcccatt
    10501 agacatgtag accttattta tatagtaggt caagatttct tgcttggttg ctttttgttc
    10561 taactgaatc gctaaccaag cttcctgagc cttacgagaa atagtctggt cggaagtcga
    10621 agttgaaaag taagtcaact taatcaactg ttgggtgaga gttgatccac cttggaggga
    10681 attgctttgc agattgcgca agaaagctcc taggatacgg atggtatcaa tccccctgtg
    10741 gtcgaagaag cgatggtctt cgatagaaac gattgcctta accaaatctg tgggaatatc
    10801 attagcttgg gcattgacgc ggcgttcaga acccaagtca gcaatgagtt gatttttatt
    10861 gtcgtagatt ttactagaag ttgttgcaac tagtttactc tcggataggc taggagcctt
    10921 gctaacgtag tagaaaaaaa ctcctccgcc taagacaatg gctgcgataa ccaagcttaa
    10981 gaagctaatg ctcagatact tgattaggcg cagaatcgtt ggtttgttca tcttgtttta
    11041 ccacctaata aatgttcttt gataacattg agataaggaa tttgagggaa ggcaccagcc
    11101 ttgatttcat atccatattc tcgaatatat tcaagtggca ttgatttttg tcccttatct
    11161 tgatgataga agcgaatcaa atcgaatgcc ggcaataagt aggtttcttg ctgagaagaa
    11221 aagtgaagaa ggacaaagca gattccttgt tgggcaagga cttgttccat atgctgaatc
    11281 tgatgtggat gaaaattttt catcggaatc gcacgttttt gttttgtttc cttgacttca
    11341 aagtcgatgt aatatccatt ataaacgcca gaatagtccg tcgttgaagc ttgtcgaaaa
    11401 taggcttcaa caatcttggc acgacttcgt tgtggatagt ccacttgtac gatttgaata
    11461 ggagttggtt tcttatgtat aacagccaag ccctgagaca aatagtagtc gttggtagca
    11521 ttgatcatct tttcaaaaga cattcctcga tttgcgaaat ttttgggttg agaaagagat
    11581 gtttgtcttt tttgtgatga aactttatgt ggatagttga ccataattct ccttattggt
    11641 acaataacat cactttatta taccataatt tgcacagaaa gggttaaaaa tggctacagc
    11701 tttggtttta ggctattctg cttttgattt gggtttattt tctgataagg atcctcgtct
    11761 taaattgatt aaaaaagcga tacgtaaaga tttagaggct atggcagcag atggggtgtc
    11821 ttggcttgtg tttacaggga gtttgggttt tgaatattgg gttttagagg ttgctcagga
    11881 gatgaaaact gaatacggtt tccagttggc caccattttt gcttttgaaa cccatgggga
    11941 aaattggaat gaaggcaatc agatgaaact gagtcgcttt aagcaggtag actttgtcaa
    12001 atatgcctat cctcgctatg aacacaaggg gcagttaaga gattaccagc agtttttgct
    12061 ggaaaacacg actagttcct atctttttta tgatgaagaa aatgaaacaa aactagctta
    12121 tttttaccaa aagatgaaaa atcaagagga ctattttata aagagattaa catttgatga
    12181 attaaatgaa cttgctgaaa atttttccga aaattgaagc tttgaccttg atttttgttt
    12241 gccttttttt atataataat actagcaagc gagaatggag agagacatgg caagtattat
    12301 tttttcagcg aaagatattt ttgaacaaga gtttggacgt gaagtccgtg gctataataa
    12361 agtagaagtt gacgagtttt tagacgatgt catcaaggac tatgaaacct atgctgcctt
    12421 ggtcaagtca cttcgtcagg aaattgcgga tttgaaggaa gaattaactc gtaaaccgaa
    12481 accttcacca gttcaagcag aaccccttga agcggcaatt acaagttcta tgacgaattt
    12541 tgatattttg aaacgcctga atagattgga aaaagaagtt tttggtaaac aaattttaga
    12601 taactcagat ttttaagtag ttatttgaga tgtgcaattt ttggataatc gcgtgaggag
    12661 aattgcttct catgaggaaa gtccatgcta gcacaggctg tgatgcctgt agtgtttgtg
    12721 ctaggcgaaa ccataagcct agggacgaga aatcgttacg gcagttgaaa tggctaagtc
    12781 cttggatagg ccagagtagg cttgaaagtg ccacagtgac ggagtctttc tggaaacaga
    12841 gagagtggaa cgcggtaaac ccctcaagct agcaacccaa attttggtcg gggcatggag
    12901 tacgcggaaa cgaacgtagt attctgactg ctatcagcta gagctgttag tggtagacag
    12961 atgattatcg aaggaagtgg tcctagtcac ttctggaaca aaacatggct tatagaaaat
    13021 tgcatatagg ttggggctga gaaattttct caacctcatt ttttaaagtg gacatataga
    13081 aaggtcttgc aagactgtaa catgaaaaaa gaatttaatt taattgcaac tgtggcagca
    13141 gggcttgagg ctgtcgttgg tcgtgaaatg cgagagttgg gctacgattg tcaggttgaa
    13201 aatggacgtg ttcgttttca aggagacgtg agagctatta tcgaaaccaa cctttggctt
    13261 cgggcagcag atcgtatcaa aattatcgta ggaacgttcc cagctaagac ttttgaagag
    13321 ctatttcagg gagttttcgc tttagattgg gaaaattatt taccacttgg agctcggttc
    13381 ccgatttcaa aagctaaatg tgttaagtcc aaacttcaca atgagcccag tgttcaggct
    13441 atttctaaga aagctgttgt caagaaattg cagaaacact atgctcgccc agaaggggtt
    13501 cctctgatgg agaatggtcc agagtttaag attgaggtct ctattctcaa agatgtggca
    13561 actgtcatga ttgatacgac cgggtctagc ctctttaaac gtggttatcg taccgaaaaa
    13621 ggtggcgctc ctatcaagga aaatatggca gcagccattt tacaactttc taactggtat
    13681 ccagacaagc ctttgattga tccgacctgt ggttcgggga ctttctgtat tgaggcagtt
    13741 atgattgcta gaaagatggc gccaggtctt cgtcgttctt ttgcatttga ggaatggaac
    13801 tggatcagcg atcgcttgat tcaagaagtg cgcacagaag cggctaaaaa agtagaccgt
    13861 gagcttgagc tggatatcat gggctgtgat attgatgctc gcatggtgga aattgctaag
    13921 gccaatgctc aggtagctgg tgttgcagga gacattactt ttaagcagat gcgcgtgcag
    13981 gatttatgtt ccgataaaat caatggagta atcatttcca atccgcctta tggtgaacgt
    14041 ttgtcagatg atgcaggggt gaccaagctc tatgctgaga tggggcaagt atttgcaccg
    14101 ctgaaaactt ggagcaaatt tatcctgact agtgatgaag cttttgaaag caagtatggt
    14161 agccaagcag ataagaagcg taagttatac aacggaacct tgaaagtgga tctatatcaa
    14221 tattttggtc agcgtgtcaa acggcaagag gtaaaataga aagggatact catgagtaaa
    14281 aaaagacgaa atcgtcataa aaaagaaggt caagaaccgc aatttgattt tgatgaagca
    14341 aaagagctaa cagttggtca agctattcgt aaaaatgaag aagtggaagc aggagtcttg
    14401 cctgaggatt ccattttgga caagtatgtt aagcaacaca gagatgaaat tgaggcggat
    14461 aagtttgcga ctcgtcaata caaaaaagag gagttcgttg aaactcagag tctggatgat
    14521 ttaattcaag agatgcgtga ggctgtagag aagtcagaag cttcttcgga ggaagttcca
    14581 tcttctgaag acatcttact acccttgcct ctggacgatg aggagcaagg cttggatcct
    14641 ctattgctag atgatgaaaa tccaacagaa atgactgaag aagtggaaga ggagcaaaac
    14701 ctttctcgtc tggatcaaga ggactcagaa aagaaaagta aaaaaggctt tattttgacc
    14761 gttttggcgc ttgtatcagt aattatttgt gtcagtgctt attatgtcta ccgtcaagtg
    14821 gctcgttcga ctaaggaaat tgaaacttct caatcaacta cagccaatca atcggatgtg
    14881 gatgatttta atacacttta tgacgccttt tacacagata gcaataaaac ggctttgaaa
    14941 aatagccagt ttgataaact gagtcaactc aagactttac ttgataagct ggaaggtagt
    15001 cgtgaacata cgcttgccaa atctaaatat gatagtctag taacgcaaat taaggccatt
    15061 caagatgtca atgcacaatt tgaaaaacca gctattgtgg atggtgtgtt ggataccaat
    15121 gccaaagcca aatcggatgc taaatttaca gatattaaaa ctgggaatac ggagcttgat
    15181 aaagtgctag ataaggctat cagtcttggt aagagccagc aaacaagtac ttctagctca
    15241 agttcaagtc aaactagcag ctcaagctct agtcaagcaa gctcaaatac gactagtgag
    15301 ccaaaaccaa gtagttcaaa tgagactaga agtagtcgca gtgaagtcaa tatgggtctc
    15361 tcgagtgcag gggttgctgt tcaaagaagt gccagtcgtg ttgcctataa tcagtctgct
    15421 attgatgata gtaataactc tgcctgggat tttgcggatg gtgtcttgga acaaattcta
    15481 gcaacttcac gttcacgtgg ctatatcact ggagaccaat atatccttga acgtgtcaat
    15541 atcgttaacg gcaatggtta ttacaacctc tacaagccag atggaaccta tctctttacc
    15601 cttaactgta agacaggcta ctttgtcgga aatggcgctg gtcatgcgga tgacttggat
    15661 tactaagcag tcgttacaaa attctttctt ttcaaaagta aaaatgataa aataaaacaa
    15721 atgaaacaag aggagtgtca aatgacaaaa gctaactttg gtgttgtagg tatggccgta
    15781 atgggtcgta accttgccct taatattgaa tcacgtggtt acacagttgc tatctacaac
    15841 cgtagtaaag aaaaaacgga agatgtgatt gcttgccatc ctgaaaagaa ctttgtacca
    15901 agctatgacg ttgaaagttt tgtaaactca atcgaaaaac ctcgtcgtat catgctgatg
    15961 gttcaagctg gacctggtac agatgctact atccaagccc ttcttccata ccttgacaag
    16021 ggtgatatct tgattgacgg tggaaatact ttctacaaag ataccatccg tcgtaatgaa
    16081 gaattggcaa actcaggtat caactttatc ggtactgggg tttctggtgg tgaaaaaggt
    16141 gcccttgaag gtccttctat catgcctggt ggacaaaaag aggcctacga attggttgcg
    16201 gatgttcttg aagaaatctc agctaaagca ccagaagatg gcaaaccatg tgtgacttac
    16261 atcggccctg atggagctgg tcactatgtg aaaatggttc acaatggtat tgagtacggt
    16321 gatatgcaat tgatcgcaga aagctatgac ttgatgcaac acttgctagg cctttctgca
    16381 gaggatatgg ctgaaatctt tactgagtgg aacaagggtg aattagacag ctatttgatc
    16441 gaaatcacag ctgatatttt gagccgtaaa gacgatgaag gccaagatgg accaatcgta
    16501 gactacatcc ttgatgctgc aggtaacaag ggaactggta aatggactag ccaatcatct
    16561 cttgaccttg gtgtaccatt gtcactgatt actgagtcag tgtttgcacg ctacatttca
    16621 acttacaaag aagaacgtgt acatgctagc aaggtgcttc caaaaccagc tgccttcaac
    16681 tttgaaggag acaaggctga attgattgaa aagatccgtc aagcccttta cttttcaaaa
    16741 atcatttcat acgcacaagg atttgctcaa ttacgtgtag cctctaaaga aaacaactgg
    16801 aacttgccat ttgcagatat cgcatctatc tggcgtgatg gctgtatcat ccgttctcgt
    16861 ttcttgcaaa agattacaga tgcttacaac cgtgatgcag accttgccaa ccttcttttg
    16921 gatgaatact tcttggatgt tactgctaag tatcaacaag cagtgcgtga tatcgtagct
    16981 cttgcggttc aagctggtgt gccagtgcca actttctcag cagctattac ttactttgat
    17041 agctaccgtt cagctgacct tccagctaac ttgatccaag cacaacgtga ctactttggt
    17101 gctcacactt accaacgtaa agacaaagaa ggaaccttcc actactcttg gtatgacgaa
    17161 aaataagtag gtcagccatg gggaaacgga ttttattact tgagaaagaa cgaaatctag
    17221 ctcatttttt aagtttggaa ctccagaaag agcagtatcg ggttgatctg gtagaggagg
    17281 ggcaaaaagc cctctccatg gctcttcaga cagactatga tttgatgtta ttgaacgtta
    17341 atctgggaga tatgatggct caggattttg cagaaaaatt gagccgaact aaacctgcct
    17401 cagtcatcat gattttagat cattgggaag acttgcaaga agagctggaa gttgttcagc
    17461 gttttgcagt ttcatacatc tataagccag tccttatcga aaatctggta gcgcgtattt
    17521 cggcgatctt ccgaggtcgg gacttcattg atcaacactg cagtctgatg aaagttccaa
    17581 ggacctaccg caatcttagg atagatgttg aacatcacac ggtttatcgt ggtgaagaga
    17641 tgattgctct gacccgccgt gagtatgacc ttttggcgac acttatggga agcaagaaag
    17701 tattgactcg tgagcaattg ttggaaagtg tttggaagta tgaaagtgcg accgagacaa
    17761 atatcgtaga tgtctatatc cgctatctac ggagcaagct tgatgttaaa ggacaaaaaa
    17821 gctacattaa aactgtgcgt ggtattggat ataccatgca agaatagaaa agcagttgca
    17881 gttgtgtaac tgcttttttg aggagttttt atatattgac atgcagtcgg gtctttgcta
    17941 caatcgtttt aggaggatat atagatgaaa cttttgaaaa aaatgatgca agttctacta
    18001 gcagtctttt tctttggttt gctagctaca aatacggtat ttgcgaatac cacaggtggc
    18061 cgatttgttg ataaggataa tagaaaatat tatgtaaaag atgatcataa agcaatctat
    18121 tggcataaaa tagacggtaa aacttactat tttggtgata ttggagagat ggttgtcggt
    18181 tggcaatact tagaaattcc tggaacaggt tatcgtgata atttattcga taaccaacca
    18241 gttaatgaaa ttggccttca ggagaagtgg tactattttg gacaagatgg tgctttgcta
    18301 gaacaaacag ataaacaagt actagaggca aaaacgtctg aaaatacagg aaaagtatac
    18361 ggtgaacaat atcctctatc tgctgaaaag agaacttatt attttgataa taattatgct
    18421 gtaaagacag gctggattta tgaagagggt cattggtatt atttaaataa gctaggaaat
    18481 tttggcgatg attcttacaa tccactacca attggtgaag ttgctaaggg ttggactcaa
    18541 gattttcatg ttactattga cattgataga agcaaacctg ctccatggta ctacctagat
    18601 gcttcaggta agatgcttac agattggcaa aaagtaaacg gaaaatggta ttattttggc
    18661 tcctctggtt ctatggcaac aggttggaaa tatgtacgag gcaaatggta ttacttagat
    18721 aataaaaatg gtgatatgaa aacaggatgg caataccttg gtaacaagtg gtactacctc
    18781 cgttcatcag gagctatggt aactggctgg tatcaagatg gttcaacttg gtactattta
    18841 gatccttcta atggagatat gaaaataggt tggacaaaag taaatggaaa atggtattat
    18901 ctcaattcaa atggagcaat ggttacaggt agccaaacta tcgatggtaa agtttataat
    18961 ttcgcctcat ctggtgagtg gatttaatat tggagggtat atagatgaaa attttgaaaa
    19021 aaactatgca agttggactg acagtatttt tctttggttt gctagggacc agtacagtat
    19081 ttgcagatga ttctgaagga tggcagtttg tccaagaaaa cggaagaacc tactacaaaa
    19141 agggggacct caaagaaacc tactggcgag tgattgatgg taagtactat tattttgatt
    19201 ctctatctgg agagatggtt gtcggctggc aatatatccc gtttccatct aaaggtagta
    19261 caattggtcc ttacccaaat ggtatcagat tagaaggttt tccaaagtca gagtggtact
    19321 acttcgataa aaatggagtg ctacaagagt ttgttggttg gaaaacatta gagattaaaa
    19381 ctaaagacag tgttggaaga aagtacgggg aaaaacgtga agattcagaa gataaagaag
    19441 agaagcgtta ttatacgaac tattacttta atcaaaatca ttctttagag acaggttggc
    19501 tttatgatca gtctaactgg tattatctag ctaagacgga aattaatgga gaaaactacc
    19561 ttggtggtga aagacgtgcg gggtggataa acgatgattc gacttggtac tacctagatc
    19621 caacaactgg tattatgcaa acaggttggc aatatctagg taataagtgg tactacctcc
    19681 gttcctcagg agcaatggcc actggctggt atcaggaagg taccacttgg tattatttag
    19741 accacccaaa tggcgatatg aaaacaggtt ggcaaaacct tgggaacaaa tggtactatc
    19801 tccgttcatc aggagctatg gcaactggtt ggtatcaaga tggttcaact tggtactacc
    19861 taaatgcagg taatggagac atgaagacag gttggttcca ggtcaatggc aactggtact
    19921 atgcttatag ctcaggtgct ttggcagtga atacgaccgt agatggctat tctgtcaact
    19981 ataatggcga atgggttcgg taatgacagg gcgcttataa ttatattaga acactcgctt
    20041 aatcaaagaa gtgactttgt tgtacttgac ctgacgattg gggagattaa aagcatgtga
    20101 aatctacaca tgctttttcg ttagttatga gtgttgaact tgactaacca ttgacaaaag
    20161 ataagagcaa ttaaaataag atacaaaaat atcaatgcta actgcaccga aacgcccgat
    20221 gctatggata gggctaatag ggagagcagg gacggggcga gaatgtccac tgtgctcaga
    20281 gcagagccca ccgtccccat cttgtcactg gggatatggg caaagacagc tgcttgtagg
    20341 cgagggctga gaatgccgat aatcgtagaa ctgatgaaac tggtcatgaa aattacgata
    20401 taggcttgac aaaggatact agttattaga gtcaataggg aaatctcaca gaaaaccaag
    20461 aggtgcgtga aacggatatt tttaaataga ttactgctgg tcatattgcc aaggatagct
    20521 ccacaagaca tgatgatgga gagcagggcg aggagttgcc caatgctcag ttgtgctagt
    20581 gtctgttgga tgaagcggag ggcaatcagc cgaggggaca catccaagat ggcaatcata
    20641 ctggtcgtca gaaacagtag tatgacggta tcttttaacc tcaggagcac agccagcgac
    20701 tgtttaagat gttgaaaata tttcttaaaa ctcagtgctg tatgtgacat ttcaattctt
    20761 ttttcaacct catacaaggt atgtcgaata acatacaggc ccaaaaaggc aatgacaaaa
    20821 gtcagagtgt tgataaggga aatagtttga atacttataa cattgataag gaatgcgcca
    20881 gccagattgg cgacaatacg gacaaccctc atcagagact gcctgaaccc catggcatca
    20941 tgcaggtcgt ccttaattac actgatgtag agggcgttca tcatgtaggc agacaggtaa
    21001 ctcaaggtgt cagagatgag gttgatgatg acaatcataa tgactgaaac taatgaaaag
    21061 ggcgacaaga cgagaaatac tgtcaaaata gcgtagagca ggattttgat tttggcaatc
    21121 cagagtgcgt gtttgactct attttcttga aaatctccta gaatcccgag aaagagttgc
    21181 gatagtaggg gaaccatctc tgaaatggaa atcagtaaaa tcgctagcgg agcgaaattg
    21241 tactgagcca cataattgat aatggcgagg tagaaaatac tgtcgccgaa tgatgaaaaa
    21301 cagctgttta gcagcaactg tctatatatg ttgtttgtcc aaaataattt catacttttc
    21361 tccttatgtc tgcacatcga atgggaattt attatttaat agacaccaat ataccccatg
    21421 cttcctattc cgaagtcaaa caaatctgct ttaccactat ctccttgaaa cataagtaaa
    21481 ccgtgatcat ctcgttcaga acatgctaaa attacctgtt ggattttttt catcagtaat
    21541 ttgttttgat tgtagacagt ggtttgtagt aagctagtta ttccgtggca atatcctgtc
    21601 atcattttta gatgatggtt aaaaacaaat tcttgatatt tactaataat atctttgttt
    21661 ccgtcacaat cgtacataca aagatataag attattccgg aaattccttt gcaccaagaa
    21721 agttgtaaat ttcctaaatt ttcagtatta gaagtaactt tttctaataa tttttttaat
    21781 tcagtatgga atgtatggag atcattatag aacatagaag gttctaagac tttagaatag
    21841 gcaaataaag catatgcaat tccacaatat ccatgagcaa agctatagtc taaaatgctt
    21901 tctttggctg tatctctttg taggaaataa tgataaattt cccctatact attgtggatg
    21961 aaaattttaa gagtattgtc attggtaaat tgatagtatt ttattaatga taataggaca
    22021 ccagattttc ccaatgcaaa gtctatttcc tctagagtat cataattctc tattaatttt
    22081 ttagcggtga cgtttgctaa ttgtagatag tattgatttt tactgataga aaataaatgt
    22141 aggagtaacc atagatagcc tgcatcacca aatagcagtg agtattgata ttcatatgtg
    22201 tgtgtcgttc taattgtcac tgccttcttg atgatagaga gtattttaga atccagttct
    22261 ggggggtaca atttatttag aggaaacagt agtccagcta ttccgtgttg gaatgataaa
    22321 ttacttacga aatttccaaa ttctgttgaa gaagtgatcc ttccttcaga atttacagtt
    22381 ttatctagta aaaattgtag aacact
//
LOCUS       DAVLBE010000029        20575 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.029, whole genome shotgun sequence.
ACCESSION   DAVLBE010000029 DAVLBE010000000
VERSION     DAVLBE010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20575)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20575)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20575
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.029"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(122..271)
                     /locus_tag="VXB91_001232"
                     /pseudo
     CDS             complement(122..271)
                     /locus_tag="VXB91_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007895229.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
     gene            complement(425..2056)
                     /gene="rlmD"
                     /locus_tag="VXB91_001233"
     CDS             complement(425..2056)
                     /gene="rlmD"
                     /locus_tag="VXB91_001233"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEV0470686.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMR
                     VLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDS
                     LYKIAGIADVEVAETLDMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHNLMPLEDFF
                     IQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFAELKKDDVIIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSQKNASLNKITNAHYVCDTAENAMKKWLKEGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVETVALLSK
                     LDVDKHISVEIELDEMDLTSAESKATYAQIKEYVWNKFELKVSTLYIAQIKKKCGIEL
                     QEHYNKSKKDKQIIPQCTPEKEEAIMDALRHFKMI"
     gene            complement(2130..3104)
                     /locus_tag="VXB91_001234"
     CDS             complement(2130..3104)
                     /locus_tag="VXB91_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HEV0470687.1"
                     /translation="MRKKLFLTSAAVLWAVTAMNSVHAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGMEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDVRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDADKALEDGGNFLSSLWQALVNFFKSFGS"
     gene            complement(3178..3792)
                     /gene="pmp23"
                     /locus_tag="VXB91_001235"
     CDS             complement(3178..3792)
                     /gene="pmp23"
                     /locus_tag="VXB91_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HEV0470688.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     KDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNTTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVQLNLYIIKCFTLFSTSG"
     gene            complement(3792..4766)
                     /locus_tag="VXB91_001236"
     CDS             complement(3792..4766)
                     /locus_tag="VXB91_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HEV0470689.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSSKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDVSRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQNENGTYSILIKNIEDIQSK"
     gene            complement(4774..6030)
                     /locus_tag="VXB91_001237"
     CDS             complement(4774..6030)
                     /locus_tag="VXB91_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HEV0470690.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMSLIEPGDTVMGMDLASGGHLTHGAPVSFSGQTYNFVSYSVDPETELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEELAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYESLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKN
                     SENEAVLEEVRSAVKELTDAFLLYED"
     gene            complement(6092..6523)
                     /locus_tag="VXB91_001238"
     CDS             complement(6092..6523)
                     /locus_tag="VXB91_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000942930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0470691.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSPEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGQGIGKSLLQGLEEEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKMQKRFIRIF"
     gene            complement(6525..7127)
                     /locus_tag="VXB91_001239"
     CDS             complement(6525..7127)
                     /locus_tag="VXB91_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HEV0470692.1"
                     /translation="MMDRIRQELENGGAVVLPTETVYGLFAKALDEKAVDHVYQLKRR
                     PRDKALNLNIASFEDILHFSKNQPTYLQKLVETFLPGPLTIILEANDRVPYWVNSDLA
                     TIGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFL
                     TGQDSTIVDLSGDKVKILRQGAIKREDILARLPEISFEEA"
     gene            complement(7111..7950)
                     /gene="prmC"
                     /locus_tag="VXB91_001240"
     CDS             complement(7111..7950)
                     /gene="prmC"
                     /locus_tag="VXB91_001240"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HEV0470693.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLETNLSVLDIGTGSGAIALALAKNRPDWSVTAADVSQEALELASENASDQNLN
                     IFFKKSDCFAEISEKYDIIVSNPPYISREDESEVGLNVLHSEPHLALFADEDGLAIYC
                     RIAEDAKDYLKDGGKIYLEIGYKQGQSVPELFRKHLPEKKVRTLKDQFGQNRMVVVDD
                     GQD"
     gene            complement(7950..9029)
                     /gene="prfA"
                     /locus_tag="VXB91_001241"
     CDS             complement(7950..9029)
                     /gene="prfA"
                     /locus_tag="VXB91_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HEV0470694.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEEMAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLEELNK"
     gene            complement(9026..9616)
                     /locus_tag="VXB91_001242"
     CDS             complement(9026..9616)
                     /locus_tag="VXB91_001242"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000068157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HEV0470695.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALAIEETTDIFGYIRDLPEKPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFAPEINKENEEK"
     gene            9739..9921
                     /locus_tag="VXB91_001243"
     CDS             9739..9921
                     /locus_tag="VXB91_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HEV0470696.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            10057..11430
                     /gene="mnmE"
                     /locus_tag="VXB91_001244"
     CDS             10057..11430
                     /gene="mnmE"
                     /locus_tag="VXB91_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HEV0470697.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTDSFAIVQKIFKGKDL
                     NKVASHTLNYGHIIDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNTRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTNLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEADLVLLVLNASEQLTAQDRQLLEISQDTNRII
                     LLNKTDLPETIETSKLPEDVIRISVLKNQNIDKIEERINNLFFENAGLVEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(11477..12412)
                     /gene="dapA"
                     /locus_tag="VXB91_001245"
     CDS             complement(11477..12412)
                     /gene="dapA"
                     /locus_tag="VXB91_001245"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HEV0470698.1"
                     /translation="MSYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKAIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     HPNIIGVKECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFTAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAILNYMGFEAGPTRLPL
                     VPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(12468..13544)
                     /locus_tag="VXB91_001246"
     CDS             complement(12468..13544)
                     /locus_tag="VXB91_001246"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HEV0470699.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGGSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPRDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIASF
                     PGAVLEDDVVHQIYPQAINAVGSRDTFVGRIRKDLDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(14175..14247)
                     /locus_tag="VXB91_001247"
     tRNA            complement(14175..14247)
                     /locus_tag="VXB91_001247"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(14212..14214),aa:Thr,seq:ggt)
     gene            complement(14347..14856)
                     /locus_tag="VXB91_001248"
     CDS             complement(14347..14856)
                     /locus_tag="VXB91_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HEV0470700.1"
                     /translation="MKKLTIRDVADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIRKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(14854..14950)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            14979..15410
                     /locus_tag="VXB91_001249"
     CDS             14979..15410
                     /locus_tag="VXB91_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HEV0470701.1"
                     /translation="MKKPIQKFFNNEILAYLFFGLATTLVSILSRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKVYIFRK"
     gene            15492..15869
                     /gene="mscL"
                     /locus_tag="VXB91_001250"
     CDS             15492..15869
                     /gene="mscL"
                     /locus_tag="VXB91_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HEV0470702.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKKE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(15911..17005)
                     /gene="hemH"
                     /locus_tag="VXB91_001251"
     CDS             complement(15911..17005)
                     /gene="hemH"
                     /locus_tag="VXB91_001251"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HEV0470703.1"
                     /translation="MKKAILMMTFGSPEEITFEGVADFFTNIRRGVRPQDHEIQTLYD
                     NYVRIGGTPLQKITRQEVALVEARLGNEYSVYFANKFSSPFIPDVIGQMEADGIEQCI
                     CLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEALLNYWADEIAKILKEEVKQD
                     SFKVIFSAHSVPIFALDFGDPYIDQIFENSKLVAEKLGLSSEQYTNTWQSESDIGIPW
                     IKPDVLEYLREQTEHPDHYIFVPISFISEHIEVLFDNDVECYDLCQEFGVNYHRPPMP
                     NTDSRLIDALVNTVRVNENQEFKEFLPEEETFDELVPSDETKNILAESEDLQMPEFVK
                     KLIEKKGRENVKMPYLIKKMLEKAGKLPKE"
     gene            17160..18383
                     /gene="pepT"
                     /locus_tag="VXB91_001252"
     CDS             17160..18383
                     /gene="pepT"
                     /locus_tag="VXB91_001252"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HEV0470704.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPGQTLITTDGTSLLGADDKSGIAEIMTAIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKEQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLMDVTGSVEEV
                     RASYIIRDFEKDAFEARKASMQSIADKMNAELGSYRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVAYKG"
     gene            complement(18419..19048)
                     /locus_tag="VXB91_001253"
     CDS             complement(18419..19048)
                     /locus_tag="VXB91_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0470705.1"
                     /translation="MSKVNQLLEQIHEEGIRQSLAEEVENLKAATNKADADLDEVNSQ
                     VKDVLTRIASALQQEKENAEQDSQTLVLYQKLYDILMSLHSYLESNNGSDADFDKVDA
                     LLDQLSAKSKDKTALLESTKAILVLNHQIQSKASASEETSPARNAEANSDNTSAENQP
                     NATAESNIEIASDENKPSNTRDSKPAESTSENETTESSTTTGNQEKPVE"
     gene            19013..19234
                     /locus_tag="VXB91_001254"
     CDS             19013..19234
                     /locus_tag="VXB91_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0470706.1"
                     /translation="MDLFQELIYLAQKTFYFFLAICRRLLVAIYHVLLKQESYNPRLQ
                     GLTEIRNPDKTMFVQDAIRFAQQHGFNML"
     gene            complement(19505..20516)
                     /locus_tag="VXB91_001255"
                     /pseudo
     CDS             complement(19505..20516)
                     /locus_tag="VXB91_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669441.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
BASE COUNT         5938 a         4322 c         3872 g         6443 t
ORIGIN      
        1 aatggatatt gtaagcagca caccaactat ttattttttg agttttaaac tttggtagaa
       61 gtcttgaact ccttatattt acataactat ttgcctctat aactgttatg acacgaaacc
      121 aacaagcaag ttcaagcacc tccatatctt tattcaaatg aggactaaga tattcacaaa
      181 ctttatcata aacctcttta tcttttttca taaaaggggc atacaactta gcaaatttat
      241 cctaaaattt tttgttgcct ttatcaatca tttcaacgct cctttaaata taaaaatgat
      301 cctatcaatc tttatattga gcctattttc taattgatac cttgcaagaa aggaataata
      361 gctgttccta taccaagtag gaatgtaata aatgcagaaa gtcatatact gtcattcttt
      421 tctattaaat cattttgaag tgtctcaaag catccatgat ggcttcttct ttttcaggtg
      481 tacactgtgg aataatttgt ttatcctttt tagacttgtt gtaatgttct tgtaattcta
      541 ttccacattt cttttttatc tgtgcaatat ataatgtcga aacttttaat tcaaatttat
      601 tccaaacata ttctttgatt tgagcatatg ttgctttgct ctccgcactt gtcaaatcca
      661 tctcatccag ctcaatttca acacttatgt gcttatcgac atcgagtttg gacaaaagtg
      721 ctaccgtctc gacgtgatgc gtttgaggaa atagatccac cggctggact ttcttcaatt
      781 catatcccaa ctcttggtat agtttaatat cacgcgccat ggttgcgaca ttgcaggaga
      841 tataggcgat gcgatcggct cctgtttggg cgcttgcttt gataaagctt tctgtcaagc
      901 ccttgcgtgg aggatcaacc aagataacgg ttggttgaat accttccttg agccatttct
      961 tcatggcatt ttcagccgtg tcacagacat agtgggcatt agtaatcttg ttcaaagaag
     1021 cattcttctg gctattctct actgcttctg gaatcagttc aacaccgtag acttctttga
     1081 catgcttggc gactgataaa ccaatggttc caataccaga ataggcatca ataatcacat
     1141 catctttttt taactctgca aagtcaatgg ctgtttgata gagtttctcc gccatttcag
     1201 tattgacttg gtaaaaggct gggccagcga tttggaagtc atttcccaac atctggtccg
     1261 taatatagtc ttgaccataa agagtgcgcc actccttacc aaaaatcgca ttggtattct
     1321 ggtcgttgat attttgcatg acagacacaa tctctgggaa ctgcttgata acttgttcaa
     1381 tcaattggtc aacacgaaaa acttttggac gagttgtcac caaaacgacc atgatttgtc
     1441 ctgaatagtg accacgacgc accacaagat tccgaatcaa tccagattgt tccttttcgt
     1501 cataaggttt taaatcaaaa cgacggagca ggtctcgaag agctactacg acttggtcaa
     1561 tgacaggatc ctggataaag aaatcttcaa ggggcatgag gttatgcgaa ttcttacgga
     1621 aaaatcctgt ttccaagaca ccattcactc gacgaacggg cacctgcgcc ttattgcgat
     1681 acttgactgg atgttccata tcaagcgttt cagcaacttc tacatctgca attccagcaa
     1741 tcttgtagag actgtccttg acttgcttgg ttttaaactt gagctgttct ggataagaaa
     1801 ggtgtcctaa atccgcgatt cctgaacgca ggtaagccaa atctagatct tgattacggt
     1861 gtggtgactg gacaaggtat ttttcaactt ttccaaagcc aatcttttta ttgaccttga
     1921 ggacacgcat gagaattttt tcactcggta aagcattctc tacaaaaaag accaaaccat
     1981 ctaccttggc aactcctgcc ccttcatggg tcaaatcaac aatttcaact tctacaatat
     2041 catttttctt taacattctt ttctctttct attggccgac aaaaaagacg gcaacgttac
     2101 ggttaccatc cattatacca tgaaatttct taagaaccaa aactcttgaa gaagttgaca
     2161 agggcttgcc agagggagct taagaagtta ccaccgtcct ctagcgcctt atccgcatca
     2221 aagttaaggt tgatattttt aaaactgtcg ccagcttgtg atacgatgct ttgtttaagg
     2281 tcatttaggg ttttagtgaa atctgcattg ctgaggatat cactctttga gagattcaag
     2341 gcaaaattga tgatgatatt gatctggttt cctgttatga cctgatcaag tttgtaattt
     2401 tttaaggtat cttcaacaat cttgcgtaca tcttcttctg tcagatttcc cttgctttct
     2461 ttagctttgg cgagtcctga cttgatatca gctagggcaa cgtttaattt attagcatca
     2521 tagcctgatt tgtccttgtt ttcagcattg atatctgaca aagcctttag ctcttcttga
     2581 gccaaatctt tattggcttg cggcaccttg gctccattag cttctagcga atagtagatc
     2641 ccagccaaag cactctcacc tgtaactgga ataggggctg ctacagtgat tttggcatgt
     2701 tccataccca gcgttactgc tgcgtttcgg tacatatcct gagtcacctt agtgatattt
     2761 tctggtgttt caatcttgac ctcaagtggc gatttgtcac ctagcttttg aatcttggct
     2821 gatgaataca actgtaagct agagtcattg gccacattca tgattttaga ataaacatca
     2881 ggtgtcatgg tcttgagttc tttggtatct gttgaggcat tgtagcccag ttttttaaga
     2941 gtttgatttt tttggtcttc agatagggag gaacctagga catattcagg ttggacatag
     3001 gtttcatcga taactttttg aacatctgtt gctgcatgga cgctattcat agctgttact
     3061 gcccacaaga ccgcagcact agtcagaaag agtttctttc tcatagggaa tttcctcctt
     3121 tacctttcta gagtaatata tctatcttaa agaaaactta taacaaaaac acctgaacta
     3181 gccagatgtt gaaaagagag tgaaacattt gatgatgtaa aggttgagtt gcacctgtct
     3241 agaataataa tagtttcctc catttacata gagttcggca ccgtgaaaaa tggaaatggg
     3301 atgaatataa ctataagtct ttccagtcgt attaccaagc aagggggcaa cagtctcacg
     3361 agagtactgt ttggctagag ccaaggtatt ttccttgcca ttttgggcga taaaatcgat
     3421 ataggcaggt ccaaaattat aggcttgaac agctgtccag atatctacac ccttcttctg
     3481 cgccagatag agattgcctg tcagagtttg aatgccttgc cgaatgctag aggcattatc
     3541 attgatggtg ttggtggaac cacttgcaga ctcactagac tgcataacat cgccttcttt
     3601 tccttttgtt tcagtataaa tcatagcaag cacaagctct tcgtttgctg gggtgtcttt
     3661 ttcactcaat atttctcgca ccatgggttg ataggtcatg acttgtttga catcttgatg
     3721 aacgcggtaa gctttatagc cagcaaaaag gaagactgct agtacaagca ctcttcgaat
     3781 tcgtttaaac attatttact ttggatatcc tcgatatttt tgattaagat agagtaggtt
     3841 ccattttcgt tttggataaa ctcaacagac tcggcgtctt gatagacgtt attgggaacg
     3901 atgagctcaa ttccatttga taaggagagt ttttggtttt caaatttctt taattggcga
     3961 ctgacatcaa tttcatcaaa ttgaacaggt tctggtacgg cttctttgac ttggtcaata
     4021 aagctcaaac gagccgtcag attgttgtca aaaaggtcat tagccaattt ctcaggtgac
     4081 aattcattgc tttcttctag gttgttgaaa atagctgatt tgaccttgga ttgaaattga
     4141 aaatcatctg tgttaaaaga ttcagcaatt ctctgggctg ttttttccag ttccttgata
     4201 gattttttag gagaaatctt aggagcgaca gcaagaagat tatctgaaaa atagttcaaa
     4261 aaagtcccgt tgtacttgat tcgtttttca atcaggtgat acttgctact ctgaagattg
     4321 accaccaagg cctcatcagc tcctgttcca aatccaggca ggttattctg agttagcttg
     4381 attggattat caacttctcc tccgaggtgg gtcaaggtct cccgcagggc aattcgcaag
     4441 aaagcgaaat gttctacacc ttctttagaa aattgaacaa aaatcaagtc attggtcttg
     4501 agattttcag aaatgctaaa ctcctctttc cagagattag ccagcgttac tgatgtctcc
     4561 aacaaatcgt ctgtaatatg attgaagaag ggattttctt cttcgaaaat cccagtcttg
     4621 gcttcatctg aatacacatg ttcaattttt ttacgcaggt attcttcgat ttttggagta
     4681 atattgagaa acttatctgc taagaacagt tcggtatcat ccggactgaa ctggtgaata
     4741 atggctttct taatataaat gtccataaaa gttttagtcc tcgtatagta ggaaggcatc
     4801 tgtcaattct ttgactgcac ttctcacttc ttctaataca gcctcatttt ctgaattctt
     4861 aagggtttta atgatgagtt cagccacttt gcgactttct tcttcaccaa atccacgtgc
     4921 agtaatggct gctgctccga tacgaatccc acttgtcttg aatggtgaca agctttcgta
     4981 agggattgag tttttattta aggtaatatt gacttcatcc aacaagtttt gagcaacttt
     5041 gccgttttct acaactttag tcacatcaac aaggaagaga tggttttcag ttccacctga
     5101 aataatacgg aaatcagggt cttgcaagaa gacatctgcc atagccttgc tgttcttaat
     5161 tacattggca gcatattcct tgaaggctgg atccaaaact tctttgaagg aaactgcctt
     5221 agccgccaca acatgctcta aaggaccgcc ctgaatacct gggaaaatag ctgaattgat
     5281 ttttttagca agttcttcgt cattggtcaa aatcaaacca ccacgaggtc cacgaagggt
     5341 tttgtgggtc gttgttgttg tgatatgagc gtatggaact gggcttggat gaaggccagc
     5401 cgcaaccaaa ccagcgatat gggccatgtc caccatgagc ttcgcaccga cagcatctgc
     5461 gatttcacgg aattttgaaa aatcgataat ttgagaatat gctgaagcac cagctacaat
     5521 cagttttggt tttacttctt gggcttgttt caagatagca tcaaagtcta agagttccgt
     5581 ttcaggatca acactataag aaacaaagtt gtaggtttga ccagagaagc taacaggagc
     5641 cccatgagtc aaatgaccac ctgatgccaa atccattccc ataaccgtat cacctggctc
     5701 aatcaaggac atgtaagccg cacagttagc ttggcttcct gaatgtggtt ggacattggc
     5761 aaatttagca ccgaaaattt cttttgcgcg ttcaatagca agagtctcta caacgtctac
     5821 tacatcagtt ccaccataat aacggcgtcc tgggtaaccc tcggcatatt tatttgtcaa
     5881 gatagaccct tgagctgcca taacagcctt ggaaactacg ttttccgaag caattaactc
     5941 gatattattt tgttggcgtt cttcttcttt ggcaatagca ttccagagat cagcatcata
     6001 tgctttaaaa tcatctttgt caaaaatcat aggtcttctc ctttattgtg tgactagtcc
     6061 attagtttga ttttacaata agaaaatcaa actaaaagat gcgaataaac cgtttctgca
     6121 ttttatcaca agtatagcca actttttcat aaaatgcatg agcacccaga cgatgattgg
     6181 cagaatttaa gcggataaac ccataaccac atctttttgc ttcttcttcc aacccttgta
     6241 gtaaactttt accaatacct tgaccttgcg cttgaggtga aactgctaaa gctaagatat
     6301 taaatcctgc tttggaatag agtgattcgt aaacttcagc gtggacatat ccaagtaaga
     6361 catgattagc tgcatcctca tagccaagta ggaaatgatg ggaatcctga gacagtctag
     6421 ctagttggct agccgtttcc tctggactaa aagtataacc caaagcctct tggttgatgt
     6481 cacatatcgc tttcacatct gtttcttgca aatctcttag catttcaagc ctcctcaaaa
     6541 gaaatctctg gcaaccgagc aagaatatct tctcgtttaa ttgcgccttg gcgtaagatt
     6601 ttcaccttgt ctccagacaa atccacaata gttgaatcct gtccagttag aaaagcatcg
     6661 tcttccagac ccagaacctc ttggtcaaaa tccttcagaa tttgttcaaa ggttacacca
     6721 cttgcctgac ctgagatatt ggcagacggc ccaatcaagg gacctgtctc tcgaattaaa
     6781 tccagtgtga tagggtgact gggcatccga aatccaatag ttgcaaggtc agaatttacc
     6841 caatagggaa ctcggtcatt ggcttcgaga ataatggtca agggacctgg caaaaaggtc
     6901 tctacaagtt tttgtagata agttggctga ttcttagaaa agtgcaagat atcctcgaaa
     6961 gaggcgatat tgagattgag tgccttatct ctaggacgac gtttgagttg gtaaacatgg
     7021 tcaactgctt tttcatctaa ggccttggca aaaagaccat aaacagtctc tgtaggtaga
     7081 acgacagctc caccattttc caactcttgt ctaatcctgt ccatcatcaa ccacaaccat
     7141 cctattttga ccaaattggt ctttgagtgt tcgaactttt ttttcaggaa gatgttttct
     7201 aaaaagttcg ggaacacttt gaccttgctt gtatccaatt tcaaggtaaa tcttaccacc
     7261 atccttgaga tagtcttttg catcttccgc aattctacag taaatagcta ggccatcctc
     7321 gtctgcaaag agagctagat gaggctccga atgcaaaaca ttcaaaccta cctctgactc
     7381 atcttcacga gagatatagg gtggattgga tacaattata tcatattttt cagaaatttc
     7441 tgcaaaacaa tcagattttt taaaaaatat attaagattt tgatcgctag cattctctga
     7501 tgcaagctct aaggcctctt gagaaacatc tgctgctgtc actgaccaat ctggtctatt
     7561 ttttgctaga gcgagagcaa tagctccact acctgttcca atatccagaa ctgagagatt
     7621 cgtctcaaga ttttcagtta gaataagctc cactaactcc tctgtttctg gacgaggaat
     7681 caaaacccgt tcatccacct ttaaatgcat tccataaaaa tctgcctgtc caatgatgta
     7741 ctgagctggc ttgtgagctg ctagttgctg gtaaatatct tctacaaatt gtttttcttc
     7801 ctctgttgtc acctcctgct ggagggcaaa aataaagtct gtaaaagata gatttttcag
     7861 actacgatag acaaaagaga ggctttccgc ttcctctcct tgtcttatca actcttcttc
     7921 aaaatttgaa aataattgag ctaatttcat tatttgttta attcttctag tttttgtgtt
     7981 tggtcataaa gcaccaaggc atccacaact tcgtccaatt taccagacaa aatcgtatct
     8041 agtttttgga gggtcaagcc gatacggtgg tctgtgacac ggttttgtgg gaagttataa
     8101 gttcggatcc gttctgaacg gtcaccagta ccgattgtcg acttacgctc agcgtcttgt
     8161 tcatcctgag caatctgagc aaagtggtca gcgacgcgtg cacggataat cttcatagcc
     8221 ttctcgcggt tcttctgctg ggtacgttct tcctgcatct caaccttgat attggttggc
     8281 aagtgaacga tacgaacggc agtcgcaacc ttattgacgt tctgtccacc agcaccagag
     8341 gcgtgataga tgtcgacacg aaggtctttt ggatcaatgt cgtattcaac ctcttcaact
     8401 tctggcataa caagaactgt cgctgtcgaa gtatgaacac ggccttggct ttctgtcaca
     8461 ggaacacgtt gcacacggtg ggcacctgat tcatacttaa gcttagagta tacagactga
     8521 cctgaaacca tagcaaccac ttctttaaaa ccaccgacac cattcataga ggcttccatg
     8581 acttcaaagc gccaaccttg ggcttccgca tacttttggt acatagttag caaatctcca
     8641 gcgaaaagtg ccgcttcgtc tccaccagct gctccacgga tttcaaggat gatattcttg
     8701 tcatcgtttg gatcctttgg aaggagcaaa attttcagtt tttcttcata ttcttctttt
     8761 tcagccttgg catctttgag ttcttgcttg gccatttctt ccaagtccgc atctccgcct
     8821 gattccttaa tcatctcttc ggcatcgacg atattttgaa ggacttgttt atactcacgg
     8881 taggctatta cggtgtcacg attggaagct tcttcttttg aaagctccat aaaacgcttg
     8941 gtgtctgaaa cgacatcagg gtcactcagc aattctccta gttcttcata acggtcttct
     9001 acagcttgta gttgatcata gatgttcatt tttcttcatt ctccttattg atttcagggg
     9061 caaaataatg tttacggcaa accgagatat aggtttcatt accaccaatc tggatctgtt
     9121 ctccatcgta aacgggcagt ccatcctgtg ttcgcaacac catggtcgcc tttttcttgc
     9181 aatactgaca gatggtcttg atttcgtcaa tcttgtctgc taaaagcaag agatatttgg
     9241 aaccttcgaa caattcattg cgaaagtcat ttttcaagcc aaaagccatg acgggtatgt
     9301 ctaactcgtc cacaacacga gctaggtcat aaacatggtg gcgtttgaga aactgggctt
     9361 catcgaccaa aacacagtaa ggtttttctg gtaggtctcg gatatagcca aagatatccg
     9421 ttgtttcctc aatcgcaagg gcagggcgtt tcatgccaat tcgactcgac acatagccaa
     9481 caccgtcacg cgtatccaga gccgaggtca taatcacaac accttttcct tgctcctcgt
     9541 agttataggc cactttgaga atctcaatcg ttttaccaga gttcatggtc ccataacgat
     9601 agtacaactg tgccatgttt cttgcttcac gtccatttct aaatttttgc tacattctag
     9661 tatatcataa ttttcttaag ctttaaacgg caaaatgtgg taaaatggaa gaaatcaaaa
     9721 ctagtggagg aagctattat gccatttgta cgcatcgatt tatttgaagg acgcacgctc
     9781 gagcaaaaga aagctcttgc taaggaagta acggaagcgg ttgttcgcaa cactggagca
     9841 cctcaatctg ctgttcatgt catcatcaac gacatgccag aaggaactta tttcccacaa
     9901 ggggaaatgc gcaccaaata agctagctta agcagaattg cttaggcttt ttcaatctcc
     9961 aagtagcacc cattgaagaa atagtctaaa tttgttacaa tttgaaaaga gacttggaaa
    10021 attccaagaa aagagcaatt aattaaagga aacattatga ttacacgtga atttgatacc
    10081 atcgctgcta tctctactcc actaggtgaa ggggctattg gtattgtccg cctgagcgga
    10141 acagacagtt ttgctattgt gcaaaagatt tttaaaggaa aagacttgaa caaggttgcc
    10201 agccacactc tcaactacgg tcacattatt gatcctctga ctggtaaagt catggacgag
    10261 gttatggttg gggctatgaa gtctccaaag accttcactc gtgaggatat tatcgagatt
    10321 aacacccacg gtgggattgc ggtgaccaat gaaattctcc agctagctat tcgtgaaggg
    10381 gctcggttgg cagaacctgg tgaatttacc aaacgtgctt ttttaaacgg tcgcgtagac
    10441 ttgacacagg cagaggctgt gatggatatc atccgtgcca agactgacaa ggccatgaac
    10501 attgcggtca aacaattaga cggctccctt tctgacctca ttaacaatac ccgtcaagaa
    10561 atcctcaata cacttgccca agttgaggtc aatatcgact atcctgaata tgatgatgtt
    10621 gaggaagcta ctactgccgt tgtccgtgag aagactatgg agtttgagca attgctaacc
    10681 aatcttctta gaacagcccg tcgcggcaaa atccttcgtg aaggaatttc aacagctatc
    10741 atcggacgtc ccaacgttgg gaaatccagc cttctcaaca acctcttgcg tgaggacaag
    10801 gctatcgtaa cagatatcgc tgggacaaca cgagatgtca tcgaagagta cgtcaacatc
    10861 aatggtgtac ctctcaaatt gattgataca gccggtattc gtgaaacaga tgacatagtg
    10921 gaacaaatcg gtgttgagcg ttcgaaaaaa gccctcaagg aagccgactt ggttctacta
    10981 gtgctaaatg ccagtgaaca actgactgcg caagacagac aacttcttga aattagccaa
    11041 gataccaatc gcattattct acttaataaa accgacctgc cagaaacgat tgaaacttcg
    11101 aaactacctg aagacgttat ccgtatttca gtccttaaaa accaaaacat cgacaagatt
    11161 gaagagcgaa tcaacaacct cttctttgaa aatgctggct tggtcgagca agatgctact
    11221 tacttgtcaa acgcccgtca catttccctg attgaaaaag cagttgaaag cctacaagcc
    11281 gttaatcaag gtcttgagct ggggatgcca gttgatttgc ttcaagttga cttgactcgt
    11341 acttgggaaa tcctcggaga aatcactggg gatgctgctc cagatgaact catcacccaa
    11401 ctctttagcc aattctgttt aggaaaataa gaaaaatcca tgatccttca ttcggtcatg
    11461 gattttattg tctttattag taatctggtc ttaagacccc tgttacagtt gccttagttg
    11521 cttcgtagtc gccatctacg acaaccttga taatgcgttt ggcatcttct tctggtgctg
    11581 gaacaagagg tagacgagtg ggtccagctt caaatcccat atagttaaga attgccttaa
    11641 ctggagcagg acttggataa gagaagagag cattaacctt aggaatgaat ttacgctgaa
    11701 ttgctgcggc tttcttcata tcgctttctg caatggcagt aaacatctcg tgcatttcat
    11761 ccccatttgt atgagaggca acagaaataa ccccatccgc cccaaggttc atggcatgga
    11821 aagcatctcc atcctcacct gtataaatca agaactcttc aggcttgtgc tcaatcaagt
    11881 aagccatatt agccaagcta gtacattctt tgacaccgat aatatttgga tggtcagcca
    11941 agcgaagcat ggtttctgga gtcaattcga caactacacg ccctggaatg ttatagataa
    12001 taattggtag gtcagaagca tctgcaatag ccttaaagtg ctgatacatc ccttcttgag
    12061 aaggtttgtt gtagtaagga acaatagcaa gcccagctgc gaaaccacca aattccgcta
    12121 cttctttgac aaactcaata gagtcacgcg tatcattagt acctacaccc gcaatcaaag
    12181 gaacgcgtcc attgacaacc ttttgtacag ccgcaaacaa ctccaactcc tcatcgtggg
    12241 tcaaagttgg actctcagca gtcgttcctg cgagaagaat tccatccgta tgatgggcca
    12301 ataaatgctc aatcaaggct ggaatagcat caaagttaat ggaaccatcc tcatggaagg
    12361 gggtaataaa ggctgtaatg attttacatt cttttaaatc ttgataagac acgaaaacac
    12421 ctctctattt caaagaagga gttcatctga actcctaaac gatatgacta ttttaattca
    12481 aatttcaatt cagctgttgg acgaaccaat ccacgttcat gaagagtttc agcaatctga
    12541 actgagttcc aagcagcacc tttgagaagg ttatctgaaa caacccacat gtgaattcct
    12601 ttttctgcat ccaagtcttt acggatacga ccaacaaagg tatcacgtga accaactgca
    12661 ttgatggctt gaggatagat ttgatgaact acatcatctt caagaacagc acctgggaag
    12721 gatgcgatag ctgctttgac ttcttcaatt ggagccactt cctttgtttc aatataaact
    12781 gactcagagt gagctgacaa gactggaata cgcacacatg tcgcagatac tgcaatgcta
    12841 tcatcttcca taattttctt agtttccttg gtcatcttca tctcttcgta cgtgtaatca
    12901 ttatcagtga agacatcaat ttgtggaaga gcgttaaagg cgataggata atgtttcttg
    12961 tcaccacctg aaggcaagat ttccgcatgc aaatcacgtg gtttcactcc atcattcaag
    13021 acctcacgaa gttcacgttg tgtctcaaga attgctccca taccagcacc tgaaacggct
    13081 tgataagttg aaacaatgat acggtccaag ccccattttt ggcgaaccgg ctcaagagcc
    13141 accatcattt ggattgttga acagttaggg caggcaatga ttccgttgtg ggcatcaagt
    13201 gcatgagcat tgacctctgg aacaaccaaa ggaacatctg gattttgacg gaaataagat
    13261 gtattatcca ctactaccac gccagctttt actgcgtatg gtgcatactt agctgatgtc
    13321 gaaccacctg ctgaaaagag agcaatatca actccttcaa aagctgtttc agtcgtttct
    13381 tcaatcgtaa tatcttgatc tttaaatttc aatgacttac ctgctgaacg tgcagaagca
    13441 aggtaacgga ttttatcgat tggaagtgtt gattcttcca acatttttat catctgagca
    13501 ccgacagcac ctgtcgcgcc gactacagca actgtatatc ccataaataa cctctttcgg
    13561 aattttctaa aaatttctat aatagaagta ttatactact ttttccatga attgcaaagc
    13621 tttttcatca ttttttggaa aataaaaatc cccaatcgct agactaggga ttaagaggca
    13681 tcttcatgtg atgagcaggt tcacacaact catcaaggtc cgctcctgcg ttatgacctc
    13741 cttatgctca atagtagccc gaagactacc tatcgactca tcgcatctac tattctacta
    13801 gatagagtca tttttgtcaa cagccaaaac tctttatact cttcgaaaat ctcttcaaac
    13861 ttcgtcagcg tcgccttgcc gtatgtatgg ttactgactt cgtcagtttc atctacaacc
    13921 tcaaaaacat gttttgagct gacttcgtca gtttcatcta caacctcaaa aacatgtttt
    13981 aagctgactt cgtcagttct atctacaacc tcaaagcagt gctttgagca acctgcggct
    14041 agtttcctag tttactcttt gattttcatt gagtattagt tttatttaca caggtgcata
    14101 agaaatatat tggaaaaatt gggggcagac ataacaaaaa cccttgtaaa tcaagggctt
    14161 ttctgtctat ttaatgctaa ttgccgggat tgaaccggcg acctcatcct taccatggat
    14221 gcgctctgcc aactgagcta aatcagctta cttaagaagt atactatatt cagaaaaact
    14281 tgtcaagttt ccttagaaat tttccatagg aaaaagccag gtaagaacta cctagcttat
    14341 cttcttctat ttacttaaat caattcgacg accaatttta ccaataataa tcgctccaat
    14401 aatcaatgaa gcaaattcac cgattcctgt tgtaaaccaa gtaaggaaga atggtaattc
    14461 tgctacaata tttaactctg cagcgatagt aaacatggaa attgaaaaga ggattgaaaa
    14521 gaagaaatga tcttttcgaa tcaatccgtt aaagaggtaa tccttgctat attttgcaaa
    14581 aagccaaaca cctaaactga ggaatactaa ggttgaacca ccaccaacaa agacatctag
    14641 cagtccgaag ctaaagaaat tagcaatcat acaaccgatg gtaactccga tgatgtactt
    14701 aggattgtaa aaagccataa agttcatcat ttctgaaata cgaaactgat aagcaccata
    14761 gctgatggca tttaggggcg gtgtgacagt caaaacgacg tagatagcag cgacgattgc
    14821 aatatctgca acatcacgaa tagttaattt tttcatcttt tctcctttgg cggttatccg
    14881 cgtgtaatat gcttggtgaa agaagctaag caccaagggt tgattcattc aaccttacta
    14941 gtatagcaca atagcctgct ttatgctata cttaaagcat gaaaaaacct attcaaaaat
    15001 tttttaacaa tgaaatctta gcctatctct tttttggcct tgcgacaact ctagtttcga
    15061 ttctctcacg actagtcatt tatcaactaa gtcatcagga actccttgct acggccttgg
    15121 caaatattat cggtatctta tttgccttta tcacaaatga tacgattgta tttaagcaaa
    15181 aaaagaaaaa tagacttatc cgtttagtga aattttctct tgctcgcctt tctacttttc
    15241 tgttagactt gtttttaact tttctctttg taacccaatt tcctcacatc atagggcaat
    15301 tcgtaactga aaacattgat aagataaatg ctattgaaac aataattgca caaatattca
    15361 ttattatcat caattatatc ttgagcaagg tctatatttt tagaaaataa tgctccattt
    15421 atgagccttt taattgcctt ctataatgat ttaggataca atgaaacacg aaacattgaa
    15481 aggaaaacag tatgttaaaa aatctaaaat cgttcttgct tcgaggaaat gttattgacc
    15541 ttgctgtcgg tgttgtcatt gcctctgctt ttggtgctat cgttacttca cttgtaaacg
    15601 acattatcac tcctcttatt ttaaatcccg ctttgaaagc tgctaaagtc gaacgtatcg
    15661 ctcaactttc ttggcatgga gtcggctatg gtaacttttt aagtgctatt atcaatttta
    15721 tctttgtggg taccgccctc ttctttatta tcaagggcat tgaaaaagca cagaaactga
    15781 ctggcataaa gaaagaaaaa actgccgaaa aaaaaccaac cgaattggaa gtccttcaag
    15841 aaataaaagc tctccttgag aaaaaataat cgattaaaag gatctagcgc aaagctaaat
    15901 ccttttttct ttactctttg ggtaacttgc ctgctttttc aagcattttt ttgataagat
    15961 aaggcatctt aacattctcc cgcccttttt tctcaatcag ttttttcaca aattctggca
    16021 tttgtaaatc ttcagattca gctaaaatgt ttttcgtctc gtctgaagga actaactcat
    16081 caaaggtctc ttcttctggg agaaattcct taaactcttg attttcattg actctaactg
    16141 tattgaccaa agcatcaatc aaacgagaat ctgtatttgg cattggtgga cgatggtagt
    16201 ttaccccaaa ttcctggcat aagtcataac attctacatc attgtcaaac aagacctcaa
    16261 tatgctcact gatgaaacta ataggtacaa aaatataatg gtctggatgt tctgtctgtt
    16321 ctctgagata ctccaaaaca tctggtttaa tccatggaat accaatatca ctctcactct
    16381 gccaagtgtt ggtatattgt tctgaactca agcccagttt ttcagcgact agcttgctat
    16441 tttcgaaaat ttggtctata taaggatcac caaagtccaa ggcaaaaatg ggcacactat
    16501 gggctgaaaa gatgacttta aagctgtctt gctttacttc ttcttttaaa atcttagcaa
    16561 tttcatctgc ccaatagttt aagagcgctt cttcctgata ccagtcctta atgaccaaaa
    16621 attgaatttg tttgctttct aaaaattttt catagcccat gacagagtag aaagaataat
    16681 ggggctccaa aatcaagcaa atacactgtt caattccgtc tgcttccatt tgaccgatca
    16741 catctggaat aaagggactg gaaaacttat tagcaaagta gacactgtat tcattcccca
    16801 gcctagcttc taccaaggca acctcttgac gggtaatttt ttgcagaggc gtgcctccaa
    16861 ttcgtacata attatcatag agagtctgaa tctcgtggtc ttggggtctc accccacgac
    16921 gaatatttgt gaaaaaatca gctacacctt caaaggtaat ctcttctggt gaaccgaagg
    16981 tcatcattaa aattgctttt ttcatgactg cttccttgtg atgtttttat caagtttatt
    17041 ttatcattaa ttaatcgata agtaaacgct aatataggga cattctcaat cttctgtctt
    17101 ttgtttttct cttctttcta tgatacaatg gaaaaaataa attcaaaagg agttttttta
    17161 tgacttatcc aaatctcttg gaccgcttct taacctacgt taaggtcaac acgcgctctg
    17221 atgaacactc tactactact ccaagtacac agagtcaggt tgacttcgca acaaatgtcc
    17281 taattcctga aatgaaacgt gttggactgc aaaatgttta ctatctaccg aatggttttg
    17341 ctattggaac cttgccagcc aacgatccgt ctttaacacg taagattggt tttatatcgc
    17401 acatggatac tgctgatttt aatgctgaag gagtcaatcc acaggtaatt gaaaactacg
    17461 atggtggtgt gattgaacta gggaattctg gtttcaaact cgatccagct gacttcaaga
    17521 gtcttgaaaa atatccagga caaacgctca tcacaacaga tggaacaagc ttgctaggtg
    17581 ctgatgacaa gtcaggaatt gctgaaatta tgacagccat tgaatatcta actgctcatc
    17641 ctgaaattaa gcactgtgag attcgtgttg gttttggtcc agatgaagaa atcggtgttg
    17701 gtgccaataa atttgatgca gaagattttg atgtggattt tgcctacact gttgatggtg
    17761 gtccactagg tgaacttcag tacgagactt tctcagccgc tggtgctgaa ttgcatttcc
    17821 aaggccgtaa tgtccaccct ggtactgcca aagagcagat ggtcaatgcc cttcagctag
    17881 caattgattt tcataatcaa cttccagaaa atgaccgacc tgagttaact gaaggttacc
    17941 aaggttttta ccatctaatg gatgtgacag gtagtgttga ggaggtgcgt gcaagctaca
    18001 tcattcgtga ttttgaaaaa gatgcctttg aagcgcgtaa agcatccatg caatctatcg
    18061 ctgataagat gaatgcagaa cttgggagct accgtgtcac tctcaacttg acagaccagt
    18121 actacaatat gaaagaagtc attgaaaaag atatgactcc aattaccatt gctaaagccg
    18181 ttatggaaga tctaggtatc acgcctatta tcgaaccaat ccggggtgga acagacggct
    18241 ctaagatttc ctttatggga atcccaactc cgaatatctt tgcaggtggc gaaaatatgc
    18301 acggacgttt tgaatacgtt agccttcaga ctatggaacg tgcagttgat accatcattg
    18361 gcatcgtagc ttataaaggc taaaaagacg aggtagctca gctacttcgc ctttcttttt
    18421 attctactgg tttttcttga tttccagtag ttgtagaaga ttctgttgtt tcattttctg
    18481 aagttgattc agcaggttta gaatctcttg tattgcttgg tttgttttcg tcgctagcaa
    18541 tttcaatgtt agattctgca gttgcgtttg gttggttctc agcactggtg ttatcactat
    18601 ttgcttcagc atttcttgct ggacttgttt cttcacttgc gctagctttt gactggattt
    18661 gatgattcaa aactagaata gcttttgtcg attcaagtaa agctgttttg tctttactct
    18721 tagcagaaag ttgatctaat aatgcatcca ccttatcaaa gtccgcatca gatccattat
    18781 tactttctaa ataagagtga agcgacatga gaatatcgta gagtttttga tagagtacaa
    18841 gtgtctgaga atcttgctca gcattttcct tttcttgttg aagggcgcta gcgatacgag
    18901 tcaagacatc ttttacctga ctgtttactt catccaagtc tgcatcagcc ttgtttgtgg
    18961 cagcttttag attttctact tcttctgcca aggattgtct gattccttct tcatggattt
    19021 gttccaagag ttgatttacc ttgctcaaaa gactttctac ttcttccttg ctatctgtcg
    19081 cagattattg gttgccatct accatgtact cctaaaacag gagagttata atccaagatt
    19141 acaaggcctt acagaaataa gaaatccaga taagacaatg ttcgtccaag acgctattcg
    19201 cttcgcacag cagcacggat tcaatatgct ttaattttaa agtttaggtg tcaagacctc
    19261 tttttagtgt gcccaaaatt tagagaagta atcaatcaac taacttttat ttttttcaaa
    19321 ctttcagtaa actgacctaa agctaactca atctgtcttt gtagatgctt ctgctatcag
    19381 ctagaagttg atctactttt gccaagactg ccttctcatc aaaagttcca ggttgatagt
    19441 tggattgcag ggatggaatc ttgtttttca aagccgcttc atatccctta gtttgaacct
    19501 tgatgtagtg attgtggtcg ccatgaggaa tcacaaaacc ttctgaatct tcacttataa
    19561 ttcgattggc atcaaaacca tgaccatctt cttcctcatg atggacatgt agtgacggat
    19621 tacttaatac agaactagaa gaacttccta cctcttccgt gttagagtgt gatgggggat
    19681 tgttaagaga tgacttagga atatagtgat agtgatcccc atgtcttact atataagcat
    19741 cacctgtatc tctgacaata tcattagggt taaagacata tgtggctgct aattcacctg
    19801 ccgacaagtc actctcagga atgaaatgat agtgaccacc atgtggtact atagtagatt
    19861 gaaatagaat atgagcaaat tgataagggg attttaaagt aatttctaac aatgatttag
    19921 aaactatgat gtgctattct aaattcaact cactatatat aaccatcatc ggtagtataa
    19981 cgtccctgta attttgctac agatacttct gcactagctc ctttatcgtc tttaccatgt
    20041 tcttgttttt ggcgattgat ttcatctttt gttcgtacat tttctgcatg agcttgatct
    20101 ttaaggtaaa cataatactt tccatctacc ttaataatat atcctccctt aacctaactg
    20161 acgatatctt gatctttcgg ctgatagttg ggggctttca ttaatagctc ttcactaaag
    20221 agcgcatcaa aaggaacttt accattatag tagtgataat gatcgccatg agaagttaca
    20281 taaccttgat ctgtaatctt aataacaatt tgttttgctt gaattccttc tttttgacta
    20341 acctagtctg gagtcaaatt ttcagtcttc ttagtgtctt tattactgtt tacatatgaa
    20401 acacgatttt tatctgtatt ggcctgttag ctatgttggt tcagagcata aacacacaga
    20461 cttaaggaaa ggataacaac agatccagct gctatatatt tctttttaaa tttcataatt
    20521 acctcatttc tataattatt tatatgatgt cttcattatt aaatgattaa ataaa
//
LOCUS       DAVLBE010000030        20155 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.030, whole genome shotgun sequence.
ACCESSION   DAVLBE010000030 DAVLBE010000000
VERSION     DAVLBE010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20155)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20155)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20155
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.030"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            156..338
                     /locus_tag="VXB91_001256"
     CDS             156..338
                     /locus_tag="VXB91_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEV0470707.1"
                     /translation="MDLKFEGVDLEYKKAKNNLPESFWETYSAFANTNGGKIILGIDE
                     KNIDTYQRVNRLPAKL"
     gene            283..994
                     /locus_tag="VXB91_001257"
                     /pseudo
     CDS             283..994
                     /locus_tag="VXB91_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1064..1426)
                     /locus_tag="VXB91_001258"
     CDS             complement(1064..1426)
                     /locus_tag="VXB91_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0470708.1"
                     /translation="MPKTKTLAELADVILWGFDFANDHAHAFFMDNVEWSHADSYFLS
                     FVSDDVEERYTENVYLDSLSVKQKFKFIFDFGDEWRFECQVLREIETEDEEAYLVRSV
                     GTSPEQYPDYDGFDYEEW"
     gene            complement(1804..3684)
                     /locus_tag="VXB91_001259"
     CDS             complement(1804..3684)
                     /locus_tag="VXB91_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEV0470709.1"
                     /translation="MVRFTGLSPKQTQAIEVLKGHISLPDVEVAVTQSDQASISIEGE
                     EGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEVLALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDMTF
                     VPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVMGWGDNGGETAQFSILPSLQIW
                     AELSYRNDLDSLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDVL
                     CPILDRHMTPEQDKPHFAQAAGTIADIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIY
                     TT"
     gene            complement(3678..4547)
                     /locus_tag="VXB91_001260"
     CDS             complement(3678..4547)
                     /locus_tag="VXB91_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV0470710.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILDKTSISTPENLEDLLAWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHGFSWYEALSSYQLPVHLENDAN
                     CVGLSELLAHPELENAACVVIGTGIGGAMIINGRLYRGRHGLGGEFGYMTTLAPAEKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAAAGNALCQEAIERMNRNLTQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQGVKKAVEDFVDAYEEYTVAPVIQACTYHADANLY
                     GALVNWLQEEKQW"
     gene            complement(4631..7276)
                     /locus_tag="VXB91_001261"
     CDS             complement(4631..7276)
                     /locus_tag="VXB91_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HEV0470711.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQV
                     LEDEQFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDL
                     DGRPVEVTIEDLGANFEYDLPKDKFRQARIARQVRVTIPVHLAPLSWTTFQLLEGEQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKGHEVLENTDRYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSE
                     ELTNIPLETELIVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFAIECHQAQERFSAYRRAKALQTPFTSLQLARQEGS
                     VVATGSLLSHSVLSIPQVCPTAFKVAENEEGYVLRYYNMSQENVRISEHQQTILDLLE
                     RPYPVHSGLLAPQEIRTEFIKKEEI"
     gene            complement(7467..8747)
                     /locus_tag="VXB91_001262"
     CDS             complement(7467..8747)
                     /locus_tag="VXB91_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HEV0470712.1"
                     /translation="MIYSKEIVREWLDEVAERAKDHPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDALLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEENWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLAYLLWKETGETSQFDEIF
                     VVATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFAALNLADSQSVIADAKRLQDEIQEGIENYAYT
                     TNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCDVNDEVYQATRRTILSSEN
                     PYFYQGEYASGLGSSHTFYRYIWPIALSIQGLTTRDKAEKKFLLDQLVACDGGTGVMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            8918..11002
                     /locus_tag="VXB91_001263"
     CDS             8918..11002
                     /locus_tag="VXB91_001263"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HEV0470713.1"
                     /translation="MKPLLETIDTRFGTTNKHAFSRGNTLPYTGVPFGMNYFVPQTSD
                     QDGAWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTSQLGEDSLFHRQSSYNRDK
                     ASFQPHYLKIFSLRYQIETQLTPTCYGASIRLKQKQGKALSLYLHATDELTVEQVDKR
                     TLALRQEGKTETNKNSLTMFTALQMNTDILAISQEAGDWRIDLVSSQTEMQLATSFIS
                     PSQALINLPQEDFDSCKSSAQADWENLLHRFDIIETGEADRTFFDHCLYRLFLFPQTF
                     YEVDESGQAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDMAPDLEGELFQAMLETASKADP
                     LGINGRHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCIASCAKKLENIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKACQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPS
                     YDLGIPLFDHLRVYLAKEDKWLDIHTKQNHNHFNFVKECRLDKILVSTIQHQDLLKAE
                     QLTFTLSWLPSH"
     gene            complement(11042..12721)
                     /locus_tag="VXB91_001264"
     CDS             complement(11042..12721)
                     /locus_tag="VXB91_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HEV0470714.1"
                     /translation="MKKIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYNQEWGTGQE
                     DPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGK
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPNYG
                     NAGKFAEVWMDGARGEGAQQVNYEFEKWFETIRDLQGDCLIFSTEGTSIRWIGNERGY
                     AGDPLWQKVNPDKLGTEAELDYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVS
                     GPALSADFACRHLTDGLETSSWANDADLPIQLELDLGSPKTFDVIELREDLKLGQRIA
                     AFHVQVEVDGVWQEFGRGFTVGHKRLLRGPLVEAQKVRVMITEAQSIPVLTKISLYKT
                     PGLSKKEVVQELAFAEKSLAVAKGENAYFTVKRRECSGPLEAKISIQPGTGVHGVAYQ
                     DEIQVLAFQAGETEKSLTLPTLYFAGDKTLYFYLNLTVDGQLVDQLQVQVS"
     gene            13477..14706
                     /gene="arcA"
                     /locus_tag="VXB91_001265"
     CDS             13477..14706
                     /gene="arcA"
                     /locus_tag="VXB91_001265"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HEV0470715.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHGIKDNQELVEKTMAGIQKVELPEIPDEAKDLTDLVESDYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIE
                     GGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGDLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
     gene            14764..15780
                     /gene="argF"
                     /locus_tag="VXB91_001266"
     CDS             14764..15780
                     /gene="argF"
                     /locus_tag="VXB91_001266"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HEV0470716.1"
                     /translation="MTNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHY
                     LAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLV
                     YCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITED
                     ADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPA
                     FHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLY
                     IPKV"
     gene            15945..16892
                     /gene="arcC"
                     /locus_tag="VXB91_001267"
     CDS             15945..16892
                     /gene="arcC"
                     /locus_tag="VXB91_001267"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HEV0470717.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVVVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNNGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFAS
                     QRLAELVDADLFIVLTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            17103..18614
                     /locus_tag="VXB91_001268"
     CDS             17103..18614
                     /locus_tag="VXB91_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HEV0470718.1"
                     /translation="MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAFIEGIYEA
                     QPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNAWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALALGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            18636..19967
                     /locus_tag="VXB91_001269"
     CDS             18636..19967
                     /locus_tag="VXB91_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HEV0470719.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICRDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEETLWRCMARY
                     NTIEEQASMGFAPDSSFPLTYAEKGLLQVKLHGPGSDQLELEVGGAFNVVPDKANYQG
                     LLYEQVCNGLKEAGYDYQTTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEIRIDIRTPVLADKE
                     ELVELLTRCAQNYQLRYEEFDYLAPLYVAKDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT"
     gene            20061..>20155
                     /locus_tag="VXB91_001270"
     CDS             20061..>20155
                     /locus_tag="VXB91_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0470720.1"
                     /translation="MKLSYEDKVQIYELRKQGQSFKQLSKRFGVDV"
BASE COUNT         5767 a         4512 c         4121 g         5755 t
ORIGIN      
        1 cgctttaatt tcttttttaa cacgtgttaa aaaagaaatt aaagcgggtt aaaaaagaaa
       61 ttaactgagt aaaaactctc gaaattcaat tcgctatatt atcactcaac ttgaacaaat
      121 accagaacca caaaaaacag atgtaaagga aaaatatgga cttaaaattt gaaggggttg
      181 atttagaata caaaaaagct aaaaacaatc ttccagagtc tttctgggaa acctactcag
      241 catttgcaaa tacaaatggc gggaaaataa ttctcggtat agatgaaaaa aacattgaca
      301 cctaccaaag agtcaataga ctccctgcga aattatgaag caagtaaaca attaactgat
      361 acacgattta agcgtcttgt tggtgttcag cgtaccactt ttaaagagat gttagctgtg
      421 ttaaaaacag attatcaact taaacacgca aaaggtggac gaaaacctaa attaagccta
      481 gaagaccttc ttatggccac tcttcaatat gtgcgagaat accgcactta tgaagaaatt
      541 gcggctgatt ttggtattca cgaaagcaac ttaatccgtc ggagccaatg ggttgaagta
      601 actcttgttc aaagtggtgt tacgatttca agaactcctc tcagttctga ggacacggta
      661 atgattgatg cgacggaagt acaaatcaat cgccctaaaa aaacaattag cgaatcattc
      721 tggtaaaatc ttggctgaca gtgattatca agggctcatg aagatatatc ctcaagcaca
      781 aactccacgt aaatccagca aactcaagcc gctaacagtt gaagataaag cctgtaacca
      841 tgcgctatct aaggagagaa gcaaggttga gaacatcttt gccaaagtaa aaacgtttaa
      901 aatgttttca acaacctatc gaaatcatcg taaacgcttc ggattacgaa tgaatttgag
      961 tgctggtatt atcaatcatg aattaggatt ctagttttgc aggaagtcta ttgaaatact
     1021 aagcctacac agactgattc caattgtttt ttagatttca attttaccat tcttcatagt
     1081 caaaaccatc ataatctgga tattgttctg gcgacgttcc aaccgaacgt acgagataag
     1141 cttcttcgtc ctctgtctcg atttctctca gtacttggca ttcaaaacgc cattcatcac
     1201 cgaagtcgaa aataaactta aatttttgtt tgacacttag gctatccaga tagacatttt
     1261 ctgtgtaacg ttcttcaaca tcgtcactaa caaagctaag aaagtaagaa tctgcatgac
     1321 tccactcaac attatccatg aaaaatgcgt gagcatgatc atttgcaaaa tcaaaacccc
     1381 ataaaatcac atctgctagt tccgctaacg tttttgtttt tggaatctat atatgtcggt
     1441 agcaaccttt tttaaatttg acggaaatga tccaagcttc tacagatgct ggcttttcag
     1501 cttctatttc ttgttttact aattttaagt gtagcataat acctccaatt gctcatcgat
     1561 agaattgctc ttaggaaaca ttcactttct gctattttat cataagtttg tctaactgta
     1621 gcatttgaaa ccagataatt cttctgtttc acgcgaaaca ccctgcgcca agcaaggtgt
     1681 tcttgttttt atactcaatg aaaatcaaag agcaaactag gaagctagct gcaggctgct
     1741 caaaacactg ttttgaggtt gtagatggaa gctgacgtgg tttgaagaga ttttcgaaga
     1801 gtattaagtc gtataaatcg tcgaagctgt cgcaatggta tgccactggt tagctgtagt
     1861 tgctgcgaaa tccttgtctg cgtagaagtc agtaaatggt aggatttcaa cttccagctc
     1921 gtcgatgcgg tcaagctggc cagccagata aacctcgata cggctttctg ctcgtttgat
     1981 gcgttgcaag agtccgccca tacggatgtc aactgtatcc aaaccaaaga ccttgttttc
     2041 tttcaaccat tggtgactaa agagggcatg gaagtcttca atttggcttc taagttctgg
     2101 taattcttgt ctggcgattt gttgtaaact ttctttatca tccgcttggt aggcctgacg
     2161 aatgcgtcgt cccacatcta ctttgctact taaaatagca ttcaactggg cctgagtttc
     2221 aaagagataa gcatagtttc cagctttttc tttaatgtca gcaatagttc ccgccgcctg
     2281 agcgaagtgt ggcttgtcct gttcaggtgt catgtgtcgg tcaagtatcg gacagagaac
     2341 atcctgataa aagacatagc ggttgggatt gatgccactg agattacctg gtaggtctgg
     2401 taagaggttg gcaaggtcaa tctgcataaa atcctcaacc gttagaccag tattggtctt
     2461 gaaatgcgca gacaaactat ctaggtcatt gcgatagctg agttctgccc agatttgcaa
     2521 gcttggtagg atagagaact gggcagtttc accaccattg tctccccaac ccattacgat
     2581 gacttcttta atctgattgg cacggcaggc tttattagcc tcgatagcca ctagacggct
     2641 aaaatggttg tgaggtgtaa agccaatcca cttccaagct ccccctgcaa atgcaaggtc
     2701 atggctaatc ttgtgatgat tgcggaaatt acggttgtat ttttcctcgc tatcctgata
     2761 ataatcccag taaaccagag tcacacggtc tttgagacgg tctaggtaga cacgagtttc
     2821 ctctggaatt tccacatcac gatcgtactg gccatccgct gacatgagtt tgaagaacat
     2881 atcactccac atctggcagt ggaaaccata tttgtcagca atatccagca cgcgctccaa
     2941 gtgttggcac atgaggagac tacgatccac aacaccgttc aaaatcaggt agcgtcccaa
     3001 accaaccaag tgggcttcgt ccatcccgat attgaccttg cgagtcttca gtttagacaa
     3061 cgtggcaaac atgccatcaa tcaggtcata aaccttttct tcgccaatga gaagaatgtc
     3121 ctctacatca cggagctcct gcacttcctt gacaccccat ttgacaaagg ccgacaagtg
     3181 ggccaaggtc tggatgcatg gtacaaaggt catgtcaaac tgttgagcat aggcttcgat
     3241 ttcctgcaac tcctctgctg aataagctcc acggaaatag ccaaagtaag gctgtccttc
     3301 aatctggtaa gtgtcttcca tgtaaagctc aaaggttgag tagcccatga gagccaagac
     3361 ctcaatcatc tgcttggcag aagccacatt cagcaccgca tttcgagaac agtcaaccat
     3421 gtaagccaaa tcttcgtaag ctgcttgttc ctcaatctct actttatcag cttctgctag
     3481 aactgttacc aacaaggata aggcacgata aagttggtga ggtttgcggt aggtcaattg
     3541 atagtgacct tcctcaccct cgatagagat agaggcttgg tcagactgag tgacagccac
     3601 ttccacatct ggtagagaaa tgtgaccttt taaaacctca atagcttgcg tttgtttggg
     3661 actaagtcct gtaaatctta ccattgcttt tcctcctgta gccagttgac aagggcaccg
     3721 tagagattgg catctgcgtg ataggtgcag gcctggataa ctggtgcgac cgtgtattct
     3781 tcgtaggcat cgacaaagtc ttcaacagcc ttcttaacac cttggataaa atctggattt
     3841 tgactgatag agccacccag actgatgaca tctggatcga tcagatactg gatattgagc
     3901 aagccttgcg tcagattgcg gttcatgcgc tcaatggctt cttgacaaag agcattacca
     3961 gctgcggcct cttggtaaat cttgcgaccg tcccaatcag tatgaccaga tttttcaatc
     4021 acgtatcgta ccatattccc agttgatgct agttgcgacc agttattaag tttttcagca
     4081 ggggcaaggg ttgtcatgta gccaaattct ccacccagac cgtggcgacc tcgataaagt
     4141 ctaccattga taatcatggc tccgccaatc cctgtcccaa tcacgacaca ggctgcattt
     4201 tcaagctctg gatgagctag tagttcactg agtccaacgc agttggcatc attttctaaa
     4261 tggacaggta gctgataaga gctaagcgcc tcataccaag aaaagccatg gatgtagggc
     4321 accgcactga agccatcaat cacacctgtc tcttgattga ccgcacctgg aacgctcata
     4381 gcaatcccac tgtaatcctg ttctgacaag cgttgatcta gccacgctag taaatcctcc
     4441 aagttttcag gcgttgaaat acttgtctta tccagtattt tcccatcagg agtcagactg
     4501 gcaaacttaa tcccagtccc tccgatatca atcgttgcaa tggtcattgt ttttaccata
     4561 aaaaggggcg aatcagcagt tagttcttac tttttcgccc ctcctttctt ttgatgttta
     4621 ctttttgaaa ttaaatttct tcttttttga tgaattctgt acgaatctct tgtggagcca
     4681 atagtcctga atgaactgga tatggtcgct caagtaagtc aagaatggtt tgttgatgtt
     4741 ctgatatgcg cacattttct tgactcatat tatagtaacg gaggacatag ccttcttcat
     4801 tttccgccac tttaaaggct gttggacaaa cttgcggtat gctgagaaca gaatggctca
     4861 agaggctacc agtcgcaacc acgcttcctt cctgtctagc aagctgaagg ctggtaaacg
     4921 gtgtctgcaa ggctttggca cgacgatagg ctgagaagcg ttcttgggct tggtggcatt
     4981 caatcgcaaa ttcgacttca aactcacgca agcattgtgc ttctggcgtt gggaagtagc
     5041 cccagtcacc tagctcacct gatgcacgca aaatggtcac ggcaatggtg ttatccccaa
     5101 ggatttcgta ttcattcaat cccttgttgg atacagtcac ccctttttca tcgtcataca
     5161 gactgacaaa agcttgttgg tgttgaggat tttcaggatt ttcccatgaa gcagctggtt
     5221 tgtttggtcg tgtcaccacc tcatagatac tttcagaatc attgcttgga cgcgtgttat
     5281 gagtcttgac caagagacgg atacggtgat ccttggcagt gttagtaaag cgagtcttga
     5341 agcggatttg tggattgtca acaaagacaa tcaactcagt ttccagagga atgtttgtca
     5401 attcttctga ccgtccagcc tcacgcttca taaactcgat gataccttgt tgctcttctt
     5461 ctagcttttc atccgcactg acaggcacgg tcaattcatg tttgagcaag attttagcat
     5521 agcgatctgt gttttccaag acctcgtggc ccttaagctc tgcaaagatt ggctctgttc
     5581 cttttggttg gaaatagata tactcgtttc cgatgtcacc ccggtcttcg aagcggataa
     5641 aatcttcata ggcttcgtga gttgtcttat catagactgt gatgttgtca tccacactca
     5701 ccgttacgaa tggtgtatca atcactccgt tttggtaaat accctcacgg tgttcttgtt
     5761 ctccttccag caattggaag gttgtccaag aaagcggtgc taggtgaact ggaatggtca
     5821 cgcgcacttg tcgagcaata cgagcttggc ggaacttatc ttttggtaaa tcgtattcaa
     5881 aattagctcc gaggtcttcg attgtaacct ctacaggacg accatccaag tcctccacac
     5941 ggtaacttgg caagataaga gcagccatct ttttgtagcc ttctgttggg tgcaattcct
     6001 tgaaatcaca agtcgccaca tcaatcactg tgctgacagt atcgacctta tcatgcaagc
     6061 ctgtgttaat gacagtaaag agatagtcac tttgagcctt atccgtagca attttaccct
     6121 tccactcgtt gagcaaatta cttttaacaa agtttcctac ttggttgacc ttggcaaaac
     6181 gcgtttccat ctcgcggtga acttcgtcca cgctacagcc acagatacta tcatgtggcg
     6241 cattctgcaa aagtgttttc caagcatagg tcaactggtc cttgtggttg tgtccaccag
     6301 tgataatagt caagggttct accacttgct ctaggaggtt gctattttct tggaaggctt
     6361 gttttaggta aatgcgggat gaagaagtgt tggcaagtgt gtaccagcca tctgtttcct
     6421 gactggtcaa ctcgcctgta acagttgata agtgttcagg aagcgcacct tctacagctt
     6481 gaacatattc atcaaaagaa ctatgaacaa agattacatc cgggaagagt tcatttgcca
     6541 cacgaatggc ttcgctcaga tttttctgta caggctggtg gtcacagccg ttcatcatca
     6601 accattggtt ggtcgaagcg taggcacgca catctgacaa tttttgtttc cagaaggtca
     6661 aggcctcatc tttgtcaact gggatttcat tcccattact gtaccagttg gcaaagagaa
     6721 tacctaaaac acgactacca tccacaccct gccagtacat ttctgaaaac tgggatgtaa
     6781 actgctcatc ttcaaggact tggttgtcaa atccaatcgg cttcacacca cgaccaaagg
     6841 ccgccacgtg aatgcctgat ttttgaagaa tttgaggcgc ttgtcccata tttccaaagg
     6901 tatctggaaa gtagccaatc tgggttgatt taccccattt ggcagcttct tgttgaccaa
     6961 tcaaggtatt gcggacattg gcttcactgg agatcaagta gtcatcctgc aagatgtaaa
     7021 agggaccaat tttaagtttg ccctcgtcaa tgtagcgttg gaccttgtcg cgattttcag
     7081 ggcgaatttg taagtagtca tcaaggacaa tagtttgtcc atccaagtgg aaactcttga
     7141 actcagggtc attttcaaag agatcaaaga gattgtcaaa caattccacc aactgcatac
     7201 gatggctttc aaaaggcaag taccactcac ggtcccagtg actatgtgag ataatatgta
     7261 caacaacatt ttccatgaag taaaacctca ttctaaattt aaattttaac gttttaaatg
     7321 taaacttgtg attctgataa gaatcggttg agctaatact caacgaaaat caaagtgcaa
     7381 actaggaagc tagccgcagg ttgctcaaag cactgctttg aggttgtaga taaagctgac
     7441 gttgtttgag agattttcga agagtattag cgaatatcca agtaatccaa gaccaactca
     7501 cagaacatca tgttagccca ggagaaccat tcacgagagt agagggtcgg atcatctacg
     7561 tggaagcttt cgtgcatgac acctgtacca ccatcgcagg caaccagctg atccagcaag
     7621 aattttttct ctgccttatc tcttgttgtc aatccttgga tagaaagggc gattggccag
     7681 atatagcgat agaaggtatg agaacttccg agaccgctag cgtattctcc ttggtagaag
     7741 tatggatttt cagagctcaa aatggtacga cgagtagctt gatacacttc atcgttgaca
     7801 tcgcagtagc ccagataggg cgcagctagt agacttggta catttggatc atccatgatg
     7861 ctggcatttc ctaggccatc cacttcaaaa gcgtaaatct tttcgccctt gctgttggtg
     7921 gtgtaagcgt agttttcgat tccttcttgg atttcatcct gaagacgctt ggcatcagca
     7981 ataacactct ggctatcagc taggtttaat gctgcgaaga tttcttgcac ataacccaag
     8041 actactacag caaacatatt tgacggaatc aagtaactat actggcaaca gtcatcactc
     8101 ggacgaaagg ctgaccaagt catacctgtc actgcaaagt caggtccaaa gccatcattt
     8161 accaaggtgt cttccttacg gtccgtatct cggacaaaac gataaggaga gttcttgtgg
     8221 tcttgttcaa ctgtccatag atggagaatt tccttagtcg ctacgacaaa aatctcatca
     8281 aactgactag tctcgccagt ctctttccag aggagataag ccaactgcaa aggatagcaa
     8341 agtgaatcca cctcatactt gcgctcccag atccagccgt taaggtctgt gtgatcagtc
     8401 tcgtggtgcc ctttccagtt ctcctcaatg ttgaaggagt tagcataggg atccttgagt
     8461 accaaggtca tctgacgttt gaccaaacct gcaatggtct gacgcaggag ggcatctctt
     8521 ttagctacat gaaggtaggg tctgagttgg gctgtcgaat cccgaagcca catggcagga
     8581 atatccccag tcaagacaaa agttgaacca tcttctaaga tttcaaccgt attgtccaag
     8641 gtatcggtgt agcaacgctc gaaaacatcc acccactctg gatggtcctt agcccgctct
     8701 gctacttcat ctagccattc tctaacaatt tctttcgaat aaatcatcgt gcaattccct
     8761 ctttcaaaca agtttcatgt tcagtatata gcttttgaga cagaaaatac atacacaaat
     8821 gatagtcatt tttctacaaa atagttattt ttgaaactcc ttttctaaag gccctctttt
     8881 tctgatataa tgtagaaaaa cagctaaagg aaagactatg aaaccactac ttgaaaccat
     8941 cgatacccgc tttggaacta ccaacaagca tgccttttct cggggaaata ccctgccata
     9001 cacaggcgtg ccttttggga tgaattattt tgtgccccag accagtgacc aggacggagc
     9061 ttggttcttc gatccgcatc tgcctatctt tcaggggatt cgattaactc accagcccag
     9121 tccttggatt ggggactact cttggctcct tctgacacct gtcaccagtc aactgggtga
     9181 agacagtctc tttcaccgcc agtcttccta taatagggat aaggcctctt tccaacctca
     9241 ttatctaaag attttctccc tgcgctatca gattgaaacc cagctcacac cgacttgcta
     9301 cggtgcttct attcgtttga agcaaaagca aggcaaagcc ctctccctct atcttcacgc
     9361 aacagatgaa ctgacagtag agcaagtaga taagcgaact cttgccctgc gacaagaagg
     9421 taaaactgaa actaacaaaa attcgctaac gatgttcact gccctgcaaa tgaacacgga
     9481 tattcttgct atcagccaag aagctggaga ctggcgaatt gacttagtaa gtagtcaaac
     9541 cgagatgcaa ctagccactt ctttcatctc tccttctcaa gctctaatca atctacctca
     9601 agaagatttt gatagctgta aatcaagtgc ccaagcggat tgggaaaatc tcctccatcg
     9661 ttttgacatt atagagacag gagaggctga ccgaaccttc tttgaccact gcctctacag
     9721 actcttcctc ttcccacaga ctttttatga ggttgatgag tcagggcaag ccatccacat
     9781 ggatctggct actggtactg tcaagcctgg tgtcctcttt agcaacaatg gtttctggga
     9841 taccttccgc accaccttcc ccctctttgc ccttatcata ccggagcact atcaacgctt
     9901 tttagaaggt ttcctcaata gctaccgcga tactggtttc cttccaaaat ggctggctcc
     9961 agatgaacgg ggtatgatgc caggtacact tttagacggt attatcgcag atagcgcctg
    10021 caaggacatg gcccctgacc tagaaggaga actcttccaa gccatgctcg aaacagccag
    10081 caaagccgac cctctcggca tcaatggccg ccacggacta gcccaatacc aagaactagg
    10141 ttacctctct accgaccacc atgaaagtgt tagccatact ctagactatg cctatagtga
    10201 cttttgtatc gccagctgtg ccaaaaaact agagaacata gaaatcgctg aaacctacaa
    10261 ggctgcttca caaaattacc gccagctatt tgacgctgag acaggttaca tgcgagcacg
    10321 agacaatcaa ggaaactttc accctgactt ctctccttat agttgggggc gagactacgc
    10381 tgaatgctct gccattcaag ctactttagg cgttctccac gacatccctg gcttaatcca
    10441 actgatgggt ggaaaagaaa cctttagcaa ctatcttttg aaagcctgtc aagatgctcc
    10501 cctctttgaa acaacaggct atggttacga aattcacgaa atgagcgaga tggctactgc
    10561 tccttttgga caaatagcca tttccaacca gcctagtttc cacattcctt atctcttccg
    10621 ctacagcgat taccctgact acactgccct tcttatcaag acgctccgtc agaaagcttt
    10681 tcacccaagt tgggaagcct atcctggaga tgaagacaat ggtagtctct ctgcttggta
    10741 catctggtca gctctcggat tttatccaac ctgtccagga aaaccaagct atgacctcgg
    10801 aatccctctc tttgaccatc tacgagtcta cctagctaaa gaagataaat ggctggatat
    10861 ccatactaaa caaaaccaca accattttaa ctttgtcaaa gaatgccgac tggacaaaat
    10921 actcgtatca actattcaac accaagacct cttaaaagct gaacaactaa ctttcaccct
    10981 cagctggtta ccaagtcact aataaccaaa agaacctttg catcgcgcaa aggttcttct
    11041 tttatgaaac ttggacttga agttgatcca caagctgacc atccaccgtt aggttcagat
    11101 agaaatacaa ggttttatct cctgcgaaat acaaggttgg tagcgtcaga cttttttcag
    11161 tctcaccagc ttgaaacgca aggacttgaa tctcatcctg ataggcgaca ccatggacac
    11221 ctgtccccgg ttgaatcgaa atcttagctt ctaaaggacc actacattct ctgcgcttaa
    11281 ctgtaaaata ggcattttct ccctttgcca cagctaggct tttttctgca aatgctagtt
    11341 cctgaacaac ttcttttttt gataatccag gagttttata aagggaaatc ttggtcaata
    11401 caggaataga ttgtgcctcg gtaatcatca cgcgcacctt ctgtgcctct actagcggac
    11461 ctcgcaagag gcgcttatga ccaactgtga agcccctgcc aaattcctgc cagacaccat
    11521 ccacctctac ttgcacatga aaagcagcga ttcgttgccc tagcttcaaa tcttctctta
    11581 actcaattac atcaaaagtt ttaggagaac ctaagtcgag ttctaactgg atgggcaagt
    11641 ctgcatcgtt tgcccaagag ctggtctcaa ggccgtctgt caaatggcga caagcaaagt
    11701 ctgcggaaag agctggacca gatacctcag ctcccagagc caaatcttct ttatagagct
    11761 cattgcgata ggtcgcaaat tcataaagtc gttcaatatc ctttgcatca aagagcccag
    11821 cttgattcgg cggaatatta agcaagagtg gagttcctcg ccctactgag tgaaagtaga
    11881 tttcgaccaa ctcctcgaga gacttaggat cctgatcctc atggtagaac cagcctggac
    11941 ggatggaaac atctgcctct ccgattgaaa aaatcgtgcc cgagggatcc ccgtgctgaa
    12001 gatagtccag ctctgcttct gttcctagtt tatcaggatt caccttttgc cacagtggat
    12061 cacctgcata ccctcgttca ttgccaatcc agcggatact ggtgccttct gttgaaaaaa
    12121 tcaaacaatc gccctgcaag tcacgaatgg tttcaaacca tttttcaaat tcataattga
    12181 cctgctgggc cccttcccct ctagcaccat ccatccaaac ctcagcgaac ttaccagcat
    12241 tcccatagtt aggatttgat aagatttcct tcaactgagc cagataatag gcattgtagt
    12301 ccgcttctcg gtccacatga tagaggggac tatgggcatc ccacggtgac aggtagaccc
    12361 ccatatccat atcaaactct gtggcagctt gggatacttc aaggagcaag tcgccctttc
    12421 ctctcctcca aggactgacc ttaaccgaat aatctgtgtg agctgtcgga taaaggacaa
    12481 agccatcgtg gtgcttgacc accaaaatca actttttgaa gcccgtttcc ttgagcacac
    12541 gaacccactc acgcgcatcc aactgactcg ggttaaagcg ctcaggatcc tcctgacctg
    12601 ttccccattc ctgattataa aaagtattag gtccaaaatg gataaaggct gctagttcat
    12661 ctcccagata agctagctga gtctgacttg gtaacggtcc atgcggtttg attttcttca
    12721 tcgttatata tctccttctt ttgcaacttc tcttgttcac aaggttatcc acaggttgtg
    12781 gataataaac catgatctaa cagccagctc tttccaactc caactggtag gctcaggatt
    12841 tttctcctca atattccctc ttcaaacagc tctgtcatat ggttctgcta acacctctca
    12901 gaatgctact ctccataatt attctcaggc ttctttcagg tcattgtgtg aagaccattc
    12961 actctccaga cttttccaca gattgtgaat aagtgattat tctaaactat cacctcgtcg
    13021 actataacaa aaaataaaaa gagggtcaat aagataatta tctcttccta aatactcaga
    13081 aaagattcta taatttgtac aattgaacaa gaaatgcttc tccaaaatct atcttcaaaa
    13141 gaatgttgca tctttttatc ctttcacaca aacatttctc tttatacaga tccaagtgat
    13201 aaccagatga taattggaca ctttttggtt atttgtgtat tttttgaaaa attttttaaa
    13261 aaaattttat atcctcttta atagaagttt atgcatttgt atatatgtat tccatcctat
    13321 gttgtgtata ataacataaa attgtgctaa atatcataat ttatattatt ttccgagaaa
    13381 ttatagccat tgacattacc taggaattgc gttataacat acatgtaagc ggtacccaaa
    13441 atggtgccaa gtcaaaattt ttaaggagga aaatacatgt cttcacatcc aattcaggtc
    13501 ttctcagaaa ttgggaaact gaaaaaagtt atgttgcacc gtccaggcaa ggagttagaa
    13561 aacttgttgc cggactatct tgaaaggctt ctttttgatg atattccttt cttggaagat
    13621 gctcaaaaag aacatgatgc atttgcccaa gctcttcgcg atgaaggaat tgaggttctc
    13681 tacctagaac aactcgctgc tgaatcattg acctctccag aaatccgcga tcaatttatc
    13741 gaggaatact tagacgaagc caacatccgt gatcgtcaaa ctaaggttgc tattcgtgaa
    13801 ttgcttcacg gcatcaagga caaccaagaa ttggttgaaa aaacaatggc tgggattcaa
    13861 aaagttgaat tgccagaaat tcctgacgaa gctaaagatc taactgactt agttgaatca
    13921 gattatccat ttgcaattga cccgatgcca aacctctatt tcactcgcga cccatttgca
    13981 acaattggaa acgccgtatc gcttaaccac atgtttgcag acactcgtaa ccgtgaaaca
    14041 ctctacggta agtatatctt caaataccac ccaatctatg gcggaaaagt ggatttggtc
    14101 tacaaccgtg aagaagatac gcgtatcgaa ggtggagacg agctagttct ttctaaagac
    14161 gtccttgcag taggtatctc tcaacgtaca gacgcagctt ctatcgaaaa acttttggtc
    14221 aacatcttca agaaaaatgt tggcttcaag aaagttttgg cctttgaatt tgctaacaac
    14281 cgtaaattca tgcacttgga tactgtcttc actatggtag actatgacaa gttcactatt
    14341 cacccagaaa tcgaaggcga ccttcacgtt tactcagtta cttacgaaaa cgaaaaactt
    14401 aaaattgttg aagagaaagg tgacttagct gaacttcttg ctcaaaacct tggtgtagaa
    14461 aaagttcatt tgattcgttg cggtggtggc aatatcgtag cagctgcgcg tgaacaatgg
    14521 aacgacggtt ctaacacttt gaccatcgca cctggtgtgg tagttgttta tgaccgcaat
    14581 accgtgacca ataagatttt ggaagaatac gggcttcgct tgattaagat tcgcggaagt
    14641 gaattggttc ggggccgtgg tggacctcgt tgtatgtcta tgccatttga acgtgaagaa
    14701 gtgtaatcgc tgttcggtat tcgtcaatag aaaatgtaaa aaatagaaag aggaaataat
    14761 aaaatgacaa attcagtatt ccaaggacgc agcttcttag cagaaaaaga ctttacccgt
    14821 gcagagttag aataccttat tggtctttca gctcacttga aagatttgaa aaaacgcaat
    14881 attcaacacc actaccttgc tggcaagaat atcgctctcc tatttgaaaa aacatctact
    14941 cgtactcgtg cagcctttac aactgcggct atcgaccttg gtgctcaccc agaatacctc
    15001 ggagcaaatg atattcagtt gggtaaaaaa gaatctactg aagatactgc taaagtattg
    15061 ggacgtatgt ttgacgggat tgaattccgc ggattcagcc aacgtatggt tgaagaattg
    15121 gcagaattct caggcgttcc agtatggaac ggtctaactg acgaatggca cccaactcaa
    15181 atgctcgctg actacttgac tgttcaagaa aacttcggtc gcttggaagg cttgacattg
    15241 gtatactgtg gtgatggacg taacaatgtt gccaacagct tgctcgtaac aggtgctatc
    15301 cttggtgtca atgttcacat cttctcacca aaagaactct tcccagaaaa agaaatcgtt
    15361 gaattggcag aaggatttgc taaagaaagt ggcgcacatg ttctcatcac tgaagatgct
    15421 gatgaagcag ttaaagatgc agacgttctt tacacagacg tttgggtatc aatgggtgaa
    15481 gaagacaaat tcgcagaacg tgtagctctt cttaaacctt accaagtcaa tatggactta
    15541 gttaaaaaag caggcaatga aaacttgatc ttcctacact gcttgccagc attccacgat
    15601 actcacactg tttatggtaa agacgttgct gaaaaatttg gtgtagaaga aatggaagta
    15661 acagacgaag tcttccgcag caagtacgct cgccacttcg atcaagcaga aaaccgtatg
    15721 cacactatca aagctgttat ggctgctaca cttggtaacc tttatattcc taaagtataa
    15781 ttttagataa taaaccgtct accaacagct atgagggctg cgactaatag ctttagtccg
    15841 gtcctctttt atataatggt aatctattat ttcttataaa atatgtgaaa aatcattaaa
    15901 ttgaaatcta aacgcattct attgagtgtg ataaaggaga atttatggca aatcgtaaaa
    15961 ttgtagtagc tttgggagga aatgcgattc tttcttctga cccatcagca aaggctcaac
    16021 aagaagcttt agttgaaaca gctaagcatc ttgtaaaatt gattaaaaat ggagatgatc
    16081 tgattatcac tcacggtaat ggacctcaag ttgggaatct cttgctccaa catttggcat
    16141 cagactctga aaagaaccct gccttcccac tcgactcact tgtcgctatg acagaaggta
    16201 gcatcggttt ctggttgaaa aatgctttgc aaaatgctct cttggatgaa ggcatcgaaa
    16261 aaaatgttgc ctctgttgta acgcaagttg tcgtagataa aaatgatcca gcttttgtta
    16321 acttgagtaa accaatcggt cctttctatt cagaagaaga agcaaaagca gaagccgaaa
    16381 agagcggagc gactttcaag gaagatgctg gccgtggctg gcgtaaggtc gttgcctcac
    16441 caaaacctgt tgacatcaaa gaaattgaaa ccatccgtac tcttttaaat aatggtcaag
    16501 tcgtcgtagc tgcaggtggt ggcggtattc ccgtcgtcaa agaaaacaat ggacatttga
    16561 ctggtgtcga agcggttatt gataaagact tcgcttccca acgtttggca gaattggttg
    16621 atgcagacct cttcatcgtt ttgacaggtg tagattatgt atttgttaac tacaacaagc
    16681 caaaccagga aaaattggaa catgtgaatg ttgcccagct ggaagaatat atcaaacaag
    16741 atcagtttgc accaggtagc atgcttccaa aagtagaagc agctatcgct tttgtcaatg
    16801 gtcgtccaga aggaaaagca gttattactt cccttgaaaa tctaggcgcc ttgattgaat
    16861 ctgaaagcgg aacaattatt gaaaaaggat aagttgtttt actaataaga tgtattctat
    16921 ttctagtatc tttatatcaa attagaaatt attcttgaaa acatgtacaa tatttcaaaa
    16981 gatattagtt ttttagactt taatatggta aaacaaatat aaatagaaag cgttttctta
    17041 aatgtttatt taagaaagta gttggttttt tacactttgt tagacatcag gaggaaaaac
    17101 aaatgagtga aaaagctaaa aaagggttta agatgccttc atcttacacc gtattattga
    17161 taatcattgc tattatggca gtgctaactt ggtttatccc tgcgggggcc tttatagaag
    17221 gtatttacga ggctcagcct caaaatccac aagggatttg ggatgtcctc atggcaccga
    17281 ttcgggctat gctaggtact catccagagg aaggttcgct cattaaagaa acgagcgcag
    17341 cgattgatgt agccttcttc atccttatgg ttggtggttt ccttggcatt gtcaacaaaa
    17401 ctggtgctct tgacgtaggg attgcctcta tcgtgaagaa gtataagggc cgcgaaaaaa
    17461 tgttaatttt ggtactgatg cctttgtttg ccctcggtgg tacaacttat ggtatggggg
    17521 aagaaacaat ggccttctat ccactccttg tgccagttat gatggccgtt ggttttgata
    17581 gcctgactgg tgttgcaatt attttgctcg gttctcaaat cggctgtttg gcatctactc
    17641 tgaatccatt tgcgacaggt attgcttcag cgactgcggg agttggtaca ggggacggta
    17701 tcgtacttcg tctgattttc tgggttacct tgactgctct tagtacttgg tttgtttacc
    17761 gttatgcgga taagattcaa aaagatccga ctaagtcact ggtttatagt actcgcaaag
    17821 aagatttgaa acactttaac gtagaagaat cttcatctgt agaatctaca cttagcagca
    17881 aacaaaaatc agttctcttc ttatttgtgt tgacattcat cttgatggta ttgagcttca
    17941 ttccatggac agaccttggc gttaccattt ttgatgactt taatgcttgg ttgactggtc
    18001 ttccagttat tggtaatatt gtcggttcat ctacttctgc actaggtact tggtacttcc
    18061 cagaaggcgc catgctcttt gcctttatgg gtatcctgat tggtgttatt tatggtctta
    18121 aagaagataa gattatctct tccttcatga atggtgctgc tgacttgctc agtgttgcct
    18181 tgatcgtagc gattgctcgt ggtattcaag ttatcatgaa cgacggtatg attaccgata
    18241 caatcctcaa ctggggtaaa gaaggcttga gcggtctatc ttcacaagtc tttatcgttg
    18301 taacttatat cttctatcta cctatgtcat tcttgatccc atcttcatct ggtcttgcca
    18361 gcgcaactat gggtatcatg gctccacttg gagaatttgt aaatgtccgt cctagcttga
    18421 ttatcactgc ttaccaatct gcttcaggtg tcttgaactt gattgcacca acatctggta
    18481 ttgtgatggg agctcttgca cttggacgta tcaacattgg tacttggtgg aaattcatgg
    18541 gcaaactcgt agtcgctatt attgtagtga ccatcgccct tcttctcctt ggaaccttcc
    18601 ttccattcct ataaaatagt gagtgaggtg attccatgaa aatagatata acaaatcaag
    18661 ttaaagatga atttcttata tcattaaaaa ccttgatttc ctatccttca gtactcaatg
    18721 aaggagaaaa tggaacacct tttggacaag caatccaaga tgtcctagaa aaaactttag
    18781 agatttgtcg agacataggt ttcactacct atcttgaccc taaaggttat tacggatatg
    18841 cagaaatcgg tcagggagca gagcttctgg ccattctctg tcatttggat gttgttccat
    18901 caggtgatga agcagattgg cagacaccgc catttgaagc aactatcaaa gacggctggg
    18961 tattcggacg tggtgtccaa gatgataaag gcccttcgct cgcagctctc tatgcagtaa
    19021 aaagcttgct ggaccaaggt attcagttca aaaagcgcgt acgctttatc tttggtaccg
    19081 atgaggaaac cctctggcgc tgcatggcac gctacaatac catcgaagaa caggccagta
    19141 tgggctttgc acctgactca tcttttcctc tgacctatgc tgaaaaaggg cttctacagg
    19201 tcaaacttca tggcccggga tcggatcaac tagagcttga agtaggaggc gcctttaacg
    19261 ttgtaccaga caaggccaac taccaaggtc tcctctatga acaggtttgt aacggtctca
    19321 aagaagctgg ttatgattac caaaccactg aacaaaccgt aacggttctc ggagtgccaa
    19381 agcatgctaa ggatgctagt caaggtatca atgctgtcat ccgactagct accattcttg
    19441 ctcctctcca agaacaccct gctctcagtt ttcttgcaac acaagcaggt caagacggca
    19501 caggaagaca aatctttggt gatatagcag atgaaccttc tggtcaccta tcctttaatg
    19561 tcgcaggtct catgatcaat catgaacgtt ctgaaatccg tattgacatt cggactcctg
    19621 tcttagctga caaggaagaa ctagtagagt tgcttacaag atgtgcacaa aactaccaac
    19681 tccgctacga agagtttgac tatctagcgc ctctatacgt cgcaaaagac agtaaactcg
    19741 ttagcacact gatgcaaatc taccaagaaa agactggcga taacagtcct gctatttcat
    19801 ccggtggtgc cacttttgct cgcaccatgc caaattgtgt agccttcggc gccttattcc
    19861 caggagcgaa gcagacagaa catcaggcaa atgaatgtgc cgttctagaa gatttgtacc
    19921 gtgctatgga tatttatgcc gaagccgtct atcgacttgc aacttaatca ggcaactgtt
    19981 tctacaaaaa aaatcgaccg attaatgaac tgcaccccaa aagttagaca gaataaatct
    20041 aacttttggg gtgttttatt atgaaattga gttatgaaga taaagttcag atctatgaac
    20101 taagaaagca aggacaaagc ttcaaacagc tttcaaaaag atttggtgtg gatgt
//
LOCUS       DAVLBE010000031        20097 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.031, whole genome shotgun sequence.
ACCESSION   DAVLBE010000031 DAVLBE010000000
VERSION     DAVLBE010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20097)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20097)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20097
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.031"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            65..976
                     /locus_tag="VXB91_001271"
                     /pseudo
     CDS             65..976
                     /locus_tag="VXB91_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(1093..1440)
                     /locus_tag="VXB91_001272"
     CDS             complement(1093..1440)
                     /locus_tag="VXB91_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV0470721.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEVEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQ
                     GPAGLVLDFYRMK"
     gene            complement(1551..3326)
                     /gene="spxB"
                     /locus_tag="VXB91_001273"
     CDS             complement(1551..3326)
                     /gene="spxB"
                     /locus_tag="VXB91_001273"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HEV0470722.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAVSKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
     gene            complement(3533..5776)
                     /locus_tag="VXB91_001274"
     CDS             complement(3533..5776)
                     /locus_tag="VXB91_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEV0470723.1"
                     /translation="MTEIVKASLENGIQKIRIQAEKGYHPAHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEPIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYTVVEKTR
                     KSLSLLQRFWITSICTVPLVILMIGMLAGSISHQVMHWGTFLATTPIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDVIGDEVEVFGLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQALHGKGV
                     SGRINGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKKNAKLAISQLKKRGLGTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QQSGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            complement(5786..6157)
                     /locus_tag="VXB91_001275"
     CDS             complement(5786..6157)
                     /locus_tag="VXB91_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HEV0470724.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHANLPMGEEYVVEITPE
                     QAGEFSFACGMNMMHGKMIVE"
     gene            complement(6168..6563)
                     /locus_tag="VXB91_001276"
     CDS             complement(6168..6563)
                     /locus_tag="VXB91_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HEV0470725.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTVQTLL
                     ARLVEKECLTRKKEGKSFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     regulatory      6747..6845
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            6929..7720
                     /gene="thiD"
                     /locus_tag="VXB91_001277"
     CDS             6929..7720
                     /gene="thiD"
                     /locus_tag="VXB91_001277"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEV0470726.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQARDVYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLESVFSDIPPQAVKTGMLATTEIMEIIQPYLKKLDCPY
                     VLDPVMVATSGDALIDSSARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEDMQRA
                     GRLILKEFGPQSVVIKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCTFAAVI
                     TAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     gene            complement(7930..8562)
                     /locus_tag="VXB91_001278"
     CDS             complement(7930..8562)
                     /locus_tag="VXB91_001278"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEV0470727.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARQVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPI
                     VAIGGLTSENIDQLMGTGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(8555..9358)
                     /locus_tag="VXB91_001279"
     CDS             complement(8555..9358)
                     /locus_tag="VXB91_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEV0470728.1"
                     /translation="MQEFTNPFPIGSSSLIHCMTNEISCEMLANGILALGCKPVMADD
                     PREVLDFTKQSQALFINLGHLSAEKEKAIRIAASYAAQVCLPMVVDAVGVTASSIRKS
                     LVRDLLDYRPTVLKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYHG
                     MSFLVTGPKDLVVSKNQVAVLGNGCAELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEVYE"
     gene            complement(9358..9882)
                     /gene="thiW"
                     /locus_tag="VXB91_001280"
     CDS             complement(9358..9882)
                     /gene="thiW"
                     /locus_tag="VXB91_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HEV0470729.1"
                     /translation="MRKHQLQVHKLTILSMMIALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFSERID"
     gene            complement(9887..10579)
                     /gene="tenA"
                     /locus_tag="VXB91_001281"
     CDS             complement(9887..10579)
                     /gene="tenA"
                     /locus_tag="VXB91_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HEV0470730.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKELEISDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            complement(10590..11240)
                     /locus_tag="VXB91_001282"
     CDS             complement(10590..11240)
                     /locus_tag="VXB91_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ABC transporter permease"
                     /protein_id="HEV0470731.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFIPSIALNLSVVAFCILFMLY
                     YRRFKMLAWMIILAILPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQELHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAHGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            complement(11242..12627)
                     /locus_tag="VXB91_001283"
     CDS             complement(11242..12627)
                     /locus_tag="VXB91_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0470732.1"
                     /translation="MGLELRAIQSPIFSEPFDFTFHAQAFTLLVGSSGSGKSSLFQMI
                     AQVSSLPYSGQVLIDGSEVSQLSIIARVQKVGILFQNPNHQFTMESLFEELIFTLENI
                     GYHLQEIDSKIAEVVQQCRCEAILHRPIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     ASIDRKSRIEILEILKELALDGKTVILCDHDLSDYKAYIDHMVELRDGKLREVFQIPS
                     YEMTQVASKEVASSPELFHMDRTTCEFGNRPLFSIADFTFYQGISCILGDNGVGKSTL
                     FRSILQFQKYKGRIAWKGSVLKKKKSLYRDLTGVVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRYFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDPLISVVDYWIEMTSQGLRHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            complement(12628..13188)
                     /locus_tag="VXB91_001284"
     CDS             complement(12628..13188)
                     /locus_tag="VXB91_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV0470733.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGLVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     regulatory      complement(13450..13538)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(13747..14376)
                     /locus_tag="VXB91_001285"
     CDS             complement(13747..14376)
                     /locus_tag="VXB91_001285"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEV0470734.1"
                     /translation="MFHKELLKLYFICGTTTCQGKNLYTVVEEALKGGITLFQFREKG
                     EGALEDLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIRNEEEFQQSKVEYVDYVGVGPVFDTQSKDDAGGAIGYEGLELMRKLL
                     PQMPLVAIGGIQTKHIKDIIKTNMDGVSIISAISYAKNIEKTVREMSEQ"
     gene            complement(14378..15160)
                     /gene="thiM"
                     /locus_tag="VXB91_001286"
     CDS             complement(14378..15160)
                     /gene="thiM"
                     /locus_tag="VXB91_001286"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEV0470735.1"
                     /translation="MTSLKLLKEKAPLVICITNDVVKNFTANGLVALGASPAMSEFPE
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPAVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVTIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVY
                     NIAGEMAEKRPNGHLPGTFKVEFINALYEITDEDVKEFKRVK"
     gene            complement(15397..16065)
                     /locus_tag="VXB91_001287"
     CDS             complement(15397..16065)
                     /locus_tag="VXB91_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HEV0470736.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENDYLEVTLHPVTKAFQDLMYSAVASSDYAHLLIMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAEWVQFLVDELNRVGKNREDLTELQQRWNQAVALELAFFDI
                     GYDV"
     regulatory      complement(16280..16368)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(16622..17758)
                     /gene="lctO"
                     /locus_tag="VXB91_001288"
     CDS             complement(16622..17758)
                     /gene="lctO"
                     /locus_tag="VXB91_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HEV0470737.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCDVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDKRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGTQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
     gene            complement(18383..19873)
                     /gene="lysS"
                     /locus_tag="VXB91_001289"
     CDS             complement(18383..19873)
                     /gene="lysS"
                     /locus_tag="VXB91_001289"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HEV0470738.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTVNSQEL
                     KDKYTNLDKEQLHDKNETATIAGRLVTKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINEPFKRVHMVDAIREITGVD
                     FWQDMTLEEAKAIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            complement(20001..>20097)
                     /locus_tag="VXB91_001290"
     CDS             complement(20001..>20097)
                     /locus_tag="VXB91_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HEV0470739.1"
                     /translation="YDLEPMAQQVIPKAAFGYIASGAGDTFTSFQ"
BASE COUNT         6035 a         4376 c         3734 g         5952 t
ORIGIN      
        1 aagtcaaact aatttataga aatattttag cagctaaggt gtactgttat agattcaata
       61 cactatagac tgtaatcaaa caacgatttg gcgaaatgta aaaaaatatg aggagttcga
      121 actcgactct ctccttcaag aaacacgtgg tggccgtaac catgcatata tgacgattga
      181 ggaaaagaaa gtctttcttg cccgccattt gaaggctaca gaggcaggag aatttgttac
      241 aattgatgcc ttatttcagg cttataaaaa ggagttaggt cgttcctaca cacgtgatgc
      301 cttctatcaa ctgttgaagc accatggttg gcgaaatatt atgccacgtc cagaacatcc
      361 taggaaagca gacgctcaaa ccattgtcgc gtctaaaaat aaaatctcaa ttcaagaaga
      421 aaagaaagcg ctttaaaagc agtagacgtt ttcgtaaggt tcgcttgatg taccaagatg
      481 aggctggttt cggtagaatc agtaaactgg gatcttgttg ggctccaata ggagtaggtc
      541 cacatgtcca tagtcactat atacgagaat ttcactattg ttatggagct gttgatgccc
      601 atacaggcga atcatttttc ttaatagctg gtggatgtaa tactgagtgg atgaacgcct
      661 ttttagaaga gctttcacaa gcttatccag atgattatct tttactcgtt atggacaatg
      721 ctatatggca taaatcaagt accttaaaga ttccgactaa tattggtttt acctttattc
      781 ctccatacac accagagatg aacccattga acaagtgtgg aaagagattc gtaaacgtgg
      841 atttaagaat aaggcctttc gaactttgga agatgtcatg aatcaacttc aagatgtcat
      901 acaaggactg gagaaggagg tgataaagtc catcgttaat cggagatgga ctagaatgct
      961 ttttgaaagc agatgagtat tatatgcaat ttctttatat aaaaagaccg gattgctccg
     1021 atctttcaat agttcatatt ctcaatttct attttaaaaa tagctaaggt taacgtcaaa
     1081 tgactacgcg acctatttca tacgataaaa atcaagcact agaccagcag gtccttgaac
     1141 taataaggac tctgttcccc aatcggttac agttggtccg tgtaaaacct ttataccaag
     1201 ctcgttcaac cgtttgtagt tctggtctac atcctcaacc tcgatatgaa taatgattcc
     1261 tgactgaaag ttttccaaag gaaccaaatg attttgtgac aacataaggc agtgactacc
     1321 aatcgtaaac tgagcaaaac catcatcagc ataatctgcc tttttatcca aaatatgctc
     1381 caagtcagca cagacttggg gaacatttga aacgataata tctaattgat ttaaattcat
     1441 ttactctcct ccataaaaag accggattgc tccgatcttt taaagttctg ctctatgaaa
     1501 atcaaagaat aaagtctaca agtttcatat ttgattttcg gcgagaggaa ttatttaatt
     1561 gcgcgtgatt gcaatccttc ttcttccaag aagagacgga atggtacgag ttcttctgct
     1621 tcgtattttt ccttgaaggc tttgatagct tcttctgagt gaagttttgg atccaattca
     1681 agtacttcta ctggaagtgg acggtgttga gtgatgcgag catcgatgac aacagtttta
     1741 ccttctttgt tcaatttaac agcttctgca acaactgcat cgatgtcttc gatacggtca
     1801 actgtgaatc caacagctcc ttgagcttcc gcaattttag cgtagtcagc gtttgtgaag
     1861 tctacaccaa acaagtgttt gtttgtatct tcgtatttgt tcttgatgaa gccgtactca
     1921 gcatttgaga agacaaggtt gataactgga aggtcgtatt gaacgtttgt gataacgtct
     1981 gggtagcaca tgttgaatgc tccgtcaccc atgatgttcc atacttggcg atctggattg
     2041 tctttcttag cagcgatacc accaggaagg gcaataccca ttgtcgcaaa gagtggagat
     2101 gtacgccaca tgttcttagg tgtcatgtga aggtgacgag tagatgtttg agtagtgtta
     2161 cctacgtcga ttgagtagat agcgtcttga tcagcatgtt tgttgattgc attgtaaact
     2221 tgatacaatt gcaattcacc ctcagtttta ccttcgagtt tgttcatgta atcacgccag
     2281 ttttggttgt tcttaacgtt tgcacgccac catggagttg attcaactgg gtttactttg
     2341 tcaaggatag ctttagctgc ttgaccagca tcaccaagga ttgaagcgtc aagggcatga
     2401 cgtttaccaa gtttgtaagg gtcgatatca acttggatga atttttcagt gttcttgaat
     2461 gcttcgtaaa cttcagcaaa tgggaagttt gaaccaagga aaagaactgt gtctgcttca
     2521 aagaccactt cgttggctgg tttccaacca acacgataag cagaacctgt caaaccttca
     2581 tagttccatt cgaaagcttc aaagttttta ccagttgtga tgattggtgc tttgatttta
     2641 cgtgacaatt cagtaatcac ttcaccagct ttaacaccac caaatccagc atagataact
     2701 gggcgttcag cattgttcaa gatttcaaca gctttgtcga tttcaacttc gttcaaagca
     2761 ggagcgatga atgagcgttc gtatgaacct gaaccgtagt atgagttttc gtcgatttct
     2821 tggaaaccga agtttactgg aatttcaaca acagctggac cttttttaga aactgcagca
     2881 cggcaggctt cgtcaattac ttttggcaat tgctcagcgt aagctacacg tttgttgtaa
     2941 acagcgatac cgttgtacat tgggttttgg ttaagctctt ggaaagcatc catgttcaat
     3001 tcgttaactg gacgtgatcc aaggattgct aggaatggag tgttatccat agctgcatcg
     3061 taaacaccgt taatcaagtg agtcgcacct ggaccacctg aaccaactgc aaccccgatt
     3121 gagccgccga atttagcttg cataaccgct gcaagagcac ctgtctcttc gtggcgaact
     3181 tgtaagaagc ggatatcttt gtcttcagcc aaagcgtcca tcaatgagct gagtgttcct
     3241 gatgggatac cgtagattgt atctacgccc catgttttca atacgttaag cattgctgca
     3301 gatgcagtaa ttttcccttg agtcataatg ataactctcc ttcaattttt ttagacttgg
     3361 agaatacgat tacatagaat tggaaacgtt ctccaatttt ttactattcc actgtatcat
     3421 atttatgctg acttttctaa aaatctgctc aaaactctct attctctatt ctaatacagt
     3481 tttgaaagtg tcgtcatttc tgttttataa caaaaaaatc tagtcattac ttttagtcta
     3541 ttttactaaa atttaacaga agggaactgg tcagaacaga tacagaacta aaggccatgg
     3601 ctagacctgc caattctggg ttgagagcca gtccaacacc tgaaaagact cctgctgcaa
     3661 tcggaattcc gacaacattg tagataaaag cccagaaaag attgagcaga atacgatgaa
     3721 aggttttctt actcatgtcg aaggcacgca ccactcctaa aagattattg gttgtcaaca
     3781 ccaaatctgc tgactcgatg gcgatatctg ttccagctcc catagcaatc cccacatctg
     3841 ctacactaag ggcaggagcg tcattgatcc catcaccaac aaaggctact ttacctgact
     3901 gttgcagttt atggatttca tgggcttttt cttctggcaa gacgcctgca atgacctctt
     3961 caattccgat ttgatctgca atagcacgcg ccacaccagc attgtctcct gtcagcatga
     4021 ctgtcccgag accacgtttt tttagctgac tgatggctag cttagcattt ttcttaggaa
     4081 tatcttgcaa agcaagcaag cctttgattt cattgtcaac agctaagaac acaactgtct
     4141 tagcttcttt ttctagttct tctagtttat cttgataagt attagaaata tccatgccat
     4201 ccagcatttt agcatttcca agtaaaactt gttttccatt gattcgccct gaaacacctt
     4261 tcccgtgcaa ggcctgaaaa ttttcaacag tttgaaactc aagtccagct tcactcgctc
     4321 gcttaacgat agcctcagcc agtgggtgtt gagaagcatc ttccaaggag gctgccaatc
     4381 caaacacttc tacttcgtcg ccgatgacat ctgttaccac aggtttccct tccgtcaaag
     4441 tcccggtctt atcaaagaca agggtttgaa ctttctggat ttcctgtaag acagttccat
     4501 ttttgaggag aacccccatc ttggcactac gtcctgtccc caccataagg gctgtcggtg
     4561 ttgcaagtcc caaggcacaa ggacaggcga taatcaaaac cgccactccg tagagaagag
     4621 aggacacaaa gctagctcca agcacaacca cactatccct gagcaagacg aaccaaaccc
     4681 aaaaggtcat gattcctaaa atgacaacta ctgggacaaa aatccctgaa atcttatccg
     4741 tcaagtcctg aatcggcgca cgacttgtct gagctttctt cacaaaatcc acaatctgag
     4801 ccaaaacagt ctctgagcca actttttctg ctctaaagac aagcgttcca ctatgattga
     4861 tggttgagcc aatgacagta tctccaactg tcttgtccac aggcagactc tcacctgtca
     4921 ccatggattc gtcaatacta gagacacctt ctactacgac accatcaaca gcaatctttt
     4981 caccgggacg cactcgaatc aggtcgccta ccttgacttg ttccaaagga acttggacat
     5041 aactatcatc actcaagact tctgcggttt tagcttgcaa gtccagtaat ttctccacag
     5101 cttgggacgt attttttctc attttttcct caaaaactgc tcccaaaaga acgaaaaaga
     5161 ggataaatcc agcactttcg aagtaaacag ggagaccagc aaagagagca actaggctat
     5221 agaaataagc cactagagtt cccagcgcaa ccaaggtatc catgttggca ttgtgctttt
     5281 taaaactggc ccaagcactc tggatatatg gcttacctgc aactaacata ataggcgttg
     5341 ttgctagaaa ggttccccaa tgcatgactt gatgactaat gctacctgcc aacatcccaa
     5401 tcatgagaat cacaagaggc acagtacaga tactagtaat ccaaaaacgt tgcaggagag
     5461 atagagattt tcgagtcttc tcaacgactg tatagcttcc cttttgcatc ttcatgccac
     5521 aagaaaattc atgtcgccct aattcttgag gtgtaaaacg aatgactttc tcctcatcta
     5581 cgccgattgg ttccaagata ccttcttctt caaacagaat ttccttataa cagtttgaag
     5641 gagtagcacg atgaaaggta atctcagctg gaattccctt ttgaagctgg atatgggctg
     5701 gatgatagcc tttttcagct tggatacgga ttttttgaat gccattttct aagcttgctt
     5761 tcacaatttc tgtcatagtc tccacctact ctacaatcat cttgccgtgc atcatgttca
     5821 taccacaagc aaagctaaac tctccagcct gttcaggcgt gatttccact acatactctt
     5881 cccccattgg caggttcgca tgtacaccaa aatctggaaa aacaatttga tccagacatg
     5941 gtgaaggatc cttgcggtca aagacaatgc gggctggcac tgatttcttg aggacaatca
     6001 actcaggagt atagcctccc atgacttcca ctcgaatctc ttggtatccg tttttttgct
     6061 gggctttttg tccagatttt tcaggctttt tgaaaaacca aaacaagata aacgcgataa
     6121 gggcaataca aataatggtt acaatactat ttaacatgac gtctccttta catacaatta
     6181 catcttactt ctgttacagc acttgatttc ttctctgaaa tcacagcttc caagtcttcc
     6241 aagtcagtct gagtaaattc acattctaca atcaagtcag ccaacaaatt cctaatccta
     6301 cgggaacaaa ccttgtcttt gatatcttgg acaagtaaat cccgactttg gtctagagtt
     6361 aaaagcgctg aataaacaaa ggacttgcct tcttttttcc gagtcaaaca ctctttctca
     6421 actagacgag ccaaaagtgt ctgaaccgtg gacttggacc agtcaaaccg ctctgccaaa
     6481 accctaatca aatctgtact ggtctgctcc ccctgcatcc aaataatctt catgacctgc
     6541 cattctgcat ctgaaatctg cattaccata cctccaaaat ctacatttgt caattacact
     6601 caacagtata ctcccaaaat ctacatttgt caattataga aataatattt tcttcgaaaa
     6661 atagaatttt aatcatttga aaaacgattt gcagtcaaat attactatat aaacaataaa
     6721 aatatgctat actaaagaaa aaagaaaaca accactaggg gtgcgtaaag ctgagattaa
     6781 cgactgttag atccctctga ctcaatctag gtaatgctag ctgatggaag tggaaatgat
     6841 aatggggact agcagtcttc tattgccttt ctaaaacaga ctagcttgtt cttaagaata
     6901 caaacttcag ttggttggga ggttttagat gacttattta cccgttgctt tgaccattgc
     6961 agggactgac cctagtggtg gtgctggcat tatggcagat ttaaagtcat tccaagcgag
     7021 agatgtctat ggaatggctg ttgtaaccag tcttgtcgct caaaatacca gaggtgttca
     7081 gctaatcgag cacgtttctc ctcaaatgtt gaaagcccaa ttggagagtg tcttttctga
     7141 tattccacct caggctgtaa aaactggaat gttggctact actgaaatca tggaaatcat
     7201 ccaaccctat cttaaaaaac tggattgtcc ctatgtcctt gatcctgtta tggttgctac
     7261 aagtggagat gccttgattg actcaagtgc tagagactat ctcaaaacaa acttactacc
     7321 tctagcaact attattacgc caaatcttcc tgaagcagaa gagattgttg gtttttcaat
     7381 ccatgacccc gaagacatgc agcgtgctgg tcgcctgatt ttaaaagaat ttggtcctca
     7441 gtctgtggtt atcaaaggcg gacatctcaa aggtggtgct aaagatttcc tctttaccaa
     7501 gaatgaacaa tttgtctggg aaagcccacg aattcaaacc tgtcacaccc atggtactgg
     7561 atgtaccttt gctgcagtga ttactgctga actagccaag ggcaagagtc tttaccaggc
     7621 agttgataag gccaaggcct ttatcacaaa agctattcaa gatgcccctc aactcggtca
     7681 tggttctggt ccagtcaacc atacaacttt taaagattaa gaaaaaaaac tctctagttc
     7741 ccactttaag ggaattagag agtttttata ctcttcgaaa atctcttcaa actacgtcag
     7801 cttccatctg caacttcaaa acactgtttt gagctgactt cgtcagtctt atctaaaacc
     7861 tcaaggcagt actttgagca acctgcgact agctttctag tttactcttt gattttcatt
     7921 gagtattaat taggaaagaa tgtcatgcaa ctttgttaaa aaggcttgcg tttttgcctc
     7981 aatatcttct gcttgcatca aatcacgtac aacagctaca ccagctatgc cagtgcccat
     8041 aagctgatca atattctccg aagtcaagcc accaatagca actattggaa tggcaaccgt
     8101 ttggcaaatt gttttcaagg ttgaaatcag ggtgatgggt gcattttcct tggtggttgt
     8161 cggaaaaatg gctcctgtcc ccaagtaatc tgcacctgat ttctccgctt ccagagctct
     8221 tttaaccgtt ttagcggtga caccgaggat tttttcagga cccaagactt gtcgggcaac
     8281 cgaaactggg agttcgtcat ctccaatatg cagaccagca gcatcaaccg caagacaaac
     8341 atccaaccga tcatcgatta tcaagggtac ctgataagca tctgttattt ccttgacttg
     8401 ttttgccagt tgataatatt gattggttgt gagatttttt tctcgcaatt ggactatggt
     8461 aacccctgaa cggcaggccg tctcaacttt tgcaagaaag ctttccacgg aatcttgata
     8521 gcgattggtt accagatata gtctaagtgc ttctctattc ataaacctct cctttgatgg
     8581 tatctagcca attttcatct cttcttagga gcgaaagctg attgagtact tggtaacgaa
     8641 attcttccaa tcccattcct tgaacaacta ttttctcagc agcgatattg agataagaga
     8701 ctgctaagca agaagcttca aaaccagtct ttccttggct gagaaaaacg gctgttaagg
     8761 ctccaaccaa atctcctgtc cctgttatcc agtctaattc tgcacagcca tttcccagta
     8821 cagcgacctg atttttcgaa acgacgaggt ccttgggacc tgtgactaag aaagacatac
     8881 catgataggt ctgacaccag tctttcaaga cttgaagcaa atcctccgtt tcttgatctt
     8941 tagcactcgc atcgacccca acgccgtggt gctttaatcc aacaagactt cgaatttctg
     9001 acatgtttcc tttaaggacc gtaggtctat agtctaaaag gtctctgact aagctcttac
     9061 gaatggatga agctgttacg ccaaccgcat ctactaccat tgggagacaa acttgagctg
     9121 cataagaagc tgctatacgg attgctttct ccttctcagc tgacaaatgc cccaaattga
     9181 tgaagagagc ctgactttgc ttagtaaaat caagaacctc acggggatca tctgccatga
     9241 caggtttgca tcccagagcc aaaatcccat ttgccagcat ctcacaagaa atctcattgg
     9301 tcatacagtg aatgagggaa ctagagccta taggaaaggg atttgtaaat tcctgcatca
     9361 gtctatcctt tcactaaaga aatatccctg cactttttta aagaattcct gcttgattaa
     9421 aaatcgaaag gcaataaagg aaatcgctgt accaatcaag gttgctccga aaaatcgagg
     9481 cgtgtagata aaccagctaa gcttagcagc tgatcctgta aagagtacca taacaggata
     9541 ggaaacaata gaaccaataa tacctgttcc cacaatttct cccaaggcag aaaagtaaaa
     9601 ttttcgaccg tacttataaa agagacctgc tagaagggct ccaaaagtcg ctcctgtgag
     9661 agctaaaggc ggaatccctt gagtcgtcat acggataaag gctgtcactg tagccatagc
     9721 caaggcataa acaggtccca tcatgattcc cgctagaata ttgactacac tggacatcgg
     9781 tgccattccc tcaatccgaa agataggtgt aaggactaca tcaagggcaa tcatcataga
     9841 taaaatggtc aatttgtgaa cttgtagttg gtgctttctc atgtttctat tcttctcctt
     9901 tttctaaaga ctgtaaatcg ctcttccatg tctggtgttg gtaagccatc tcccaaaact
     9961 tggcttccat atgaacactg atgtggaagg catctagcat tttttgctta tctgtctcat
    10021 cactttctcg atagagctga ttgaccagtg ctccctcctc tctgatctgt tgctctaact
    10081 catccgtaat ataagtttca atccattgtt gatagagagg atttggtgat ggtttaagat
    10141 taagtgattt gcctatatca tggtataacc aaggacaagg aagcaagctt gcaaaagcga
    10201 tggctaagtt cggttctgca aattgcctat aaatatgaga aatgtaatga taacaggttg
    10261 gagcgattgg atgttgctcc atttcctggt cgctgatttc caattccttg aaaaattgtt
    10321 ggcgaataaa taactcaccc tccactaaac cctgagcatt ttgtttcaag agtcttttca
    10381 tctcttggtt tgaagtctta tcagccaaaa gatgatagat ttctgagaaa gccttcagat
    10441 agtaggcatc ctgaatcagg taatagcgga aaatggcagg ttctaaattc ccctcttgta
    10501 attgtaaaat aaagggatga tgaaaggaag cctgccaagc tttcttggat aattccatcg
    10561 caatatctgt aaattccata ataactcctt tataaaaata gactggtttg aagcaataaa
    10621 aagaaaagca ggtagattaa ttttgttttt ttaggaatat aaaaagtccg atagctattc
    10681 ttcaactgtg catgttcgtc atatccgtga gcagatagag ctctcaggta aagatggcgc
    10741 cacctaaaga ctgtcatcag aaccttactg taaatcaagg gcgaccaaaa atgtagttct
    10801 tgaccacgta ataggcaagc ttctttgagg gacttgattt cttgctgaat gagaggaaaa
    10861 gaattgaata ccacaatcaa ggcataggac caagagcgtg atagcccctt ttgagccaag
    10921 tacaagagaa gctcttttag tgaaatagag gaaacaaaga caaggccgat acaaactgtc
    10981 acaaaggccc tcgttccaag catgactgcc tgtgaagcat ctccgtgtaa ctgaactgcc
    11041 cagtagttgg caaaagatgg taaaatggca agtatgatca tccaagctaa cattttaaat
    11101 cgacggtaat agagcataaa gagaatacaa aatgcgacta ccgaaagatt cagagcaatc
    11161 gaaggaatga aagatgtttc caaggataaa atcagcaaga agagactgat aatcggtgtc
    11221 tgggttgcta ctttgaccat actatctcac ctccccttgg gtattgctac tctgagatgt
    11281 aagtggtttg gtaatggtca cttctttcac atgccgaaga ccctgactag tcatctcaat
    11341 ccaataatca accacagaaa tcaaagggtc taaacgatga ctaatgagca gaaaacttct
    11401 tccttgattc ctctcctcca caatccactt gcaaaaataa tggcaggctc tatcatccaa
    11461 acctgcaaaa ggttcatcta gcaagatcac ggaagcctta ctggtcaaga tggtcaggag
    11521 ctgaagaatt ttttgctgac caccacttaa ttgataggga ctcttatcga ctgcctgctc
    11581 caaatcaaaa tatcgtaaag cttgaaaaat ccgctgattt ctttcagaat caggtccatc
    11641 taattgaagc tcctctcgca gactgactcg gataaactgc ttctcagctt cctgaacaac
    11701 accagtcaga tcacgataca aactcttttt ctttttcagg accgaaccct tccatgcaat
    11761 gcgcccctta tacttttgaa attgaagaat agaccgaaag agggttgatt tcccgacacc
    11821 attgtcaccc aggatacagg aaatcccttg atagaatgtg aaatcagcaa ttgaaaagag
    11881 ggggcgattt ccaaactcac aagtcgttct atccatatgg aatagttccg ggctagaagc
    11941 aacttccttt gaagcaacct gtgtcatctc ataggaaggg atttgaaaca cttcccttag
    12001 ttttccgtct cttagctcaa ccatatggtc gatataggct ttatagtcag ataaatcatg
    12061 gtcgcacaaa ataactgtct ttccatcaag agccaactct tttagaatct ccaatatctc
    12121 gattctgctc ttgcggtcaa tggaagcaaa aggttcatcc aagagataga ccctaggatt
    12181 catggcaaag aggacagcca gcgctgcttt ttgcttttcc ccacctgata ggtgatgaat
    12241 gggacggtgt aagattgcct cgcaacgaca ttgctggaca acctctgcta ttttagaatc
    12301 aatttcctga aggtgatagc cgatattctc caaggtgaaa atcagctcct caaacaagct
    12361 ctccatggta aattgatgat tgggattttg aaagagaatg ccaaccttct ggacacgtgc
    12421 gatgatagaa agttgactga cctcgctccc atctatcagg acttgaccac tatagggaag
    12481 agaactgact tgggcaatca tttgaaagag gctggatttt ccagacccac tactcccaac
    12541 taacaaggta aaggcttgcg catgaaaagt aaaatcaaac ggctcagaga agattgggga
    12601 ctgaatcgct cgtagttcca gacccatcta tgcttttcct ccagttgcaa actgatgata
    12661 gagtttgaca atggcacgaa ccaagatggt acagaagaaa taaacagaaa taaaacgtac
    12721 cacaagtaag gaaaggacaa acggaaggga aaaggcgtag taacctaact taatgtattc
    12781 atagacaaag ctaacaagcg taatcccaat actattagca gttagagaga gccaactttc
    12841 atagcgattc ttagttacga taaaaccaaa ttcacttccc aaaccttgaa ccaagccaga
    12901 caaaagagct cctagaccaa attggctacc ataaaggact tcagcaagcg cagctagcac
    12961 ttctccaatc gttgcacttc cgactctcgg aacaaagatg gcagcaatgg gcgcagccat
    13021 acaccagaga ccgaagagga tttcattggc aaaggcctgc aaaccaagag gtgttaagag
    13081 tagactgaga atattataca catatcctga accaacgaaa accccaccaa aaaagataga
    13141 caagaaagca agcaagataa catcttttaa ctgccatttt ttcaacataa aaaactcctt
    13201 tttttaaaga aaagtggggc actcaagaag accgacctaa atactttgta tagcagactg
    13261 aatttagaac agtacacaag aatgctaaaa tatttctaga aattaatttg aattttctaa
    13321 ttgatttgtt cgcatcttat ttcaatctac tatatcatct tcatccagtt tcgtaaaaga
    13381 aaaaactcta attacagata cgaattagag ttcagcttac aagattagac agttcttttc
    13441 gacatacgaa aaaaacattt cacatttccc ttcgccagtc ttaactgtat caggttcaat
    13501 gggtatcatc tcagcctaaa gcaccccaaa tgtctttatt atttaattat gtgattatta
    13561 taacacacat tttatactag ttcaagaaat tgaactggaa atacagcctt gcactcacaa
    13621 agacagcaga tctttctttt gcaaaaaaca aatgacctgt ttgatgaatt agccattcaa
    13681 gctgaatctg gacatagctt tttaaaaaag gaaaatccta cttacttaga atccaaggat
    13741 agatatctat tgttcactca tttcccgaac agttttttct atattttttg catacgatat
    13801 tgccgaaatg attgaaacgc catccatatt ggtctttata atgtctttaa tatgtttcgt
    13861 ctgtatccca ccaattgcaa ctaaaggcat ttgtggcaat agttttctca tcaattcaag
    13921 accttcataa cctatagcac caccagcatc atcttttgac tgggtatcaa atacaggccc
    13981 aacacctaca taatctacat attcaacttt tgattgttga aattcttctt cgtttcttat
    14041 agaaagacca attattttat ctggcatcaa ttttctaatt tcatcaacac caatatcatc
    14101 ttgacctaca tgtacgccat cggcgtcaat ttccattgct aaatctatat cgtcattaac
    14161 gataaatgga acattgtatt ttttacaaag ttctttaatt tggatagcta gctcaagttt
    14221 ttctaagtct tctaaagcac cctcaccttt ttctcgaaat tgaaataagg ttataccacc
    14281 ttttaaggct tcctcaacga ctgtatatag attttttcct tggcaagtag tcgttccaca
    14341 aataaaatat agttttagta attctttatg aaacatctta cttcactctt ttgaattcct
    14401 ttacatcttc atctgtaatc tcgtataagg catttataaa ttcaacttta aatgtcccag
    14461 gaagatgtcc atttggacgt ttttctgcca tttctccagc gatattgtaa actaacattg
    14521 ctgtttctaa tgattttaat tcttgacctt tttccagtcc gataaaactt gctactacag
    14581 ctcctaataa acatccagtt ccaataactt ttggcatcat ggcactacca ttatgaatcg
    14641 ttaccacttc tccatttacc gcaatagcat ccacttcacc tgttactact attggaatat
    14701 tgaacttctc atttgctgct agagcaatct cgtcaatatt atctactccc gcactatcta
    14761 ctcctttaga tgccacatct attcctacta aagaggcaat ctctccagca ttccccctaa
    14821 tcgcagctag tttgtaattg ttgattaaat catctgctac tttttttcta tattctcctg
    14881 ctccacaggc tacaggatct aaaactgctg ggacattata tttctctgca attttcagag
    14941 cagcttggta taatttccaa ttttcatctg tcaatgttcc tatgtttatt aataaaccac
    15001 cagcatactt taataagtcc tctaaatctt ctggaaactc actcatggct ggtgaagcgc
    15061 ccagtgctac taatccattt gctgtgaaat tttttactac atcattggtg atgcaaatga
    15121 ccaaaggtgc tttttctttt aataatttta aacttgtcat attgaaatcc ttccttttca
    15181 ctttatacga tctactaatt tcgatttatc tttagttgag aatttttttc atttacattg
    15241 aatgatttat actcaatgaa aatcaaagag caaactagga ggctaaccgc aggttgctca
    15301 aaacactgtt ttgaggttgt ggatagaact gacgtggttt gaagagattt tcgaagagtc
    15361 ttacctcatc aaatttgtaa atatcatgag ccttctctag acatcgtaac caatatcaaa
    15421 aaaagctaat tctaaagcga ctgcttgatt ccagcgttgc tgaagttctg tcaaatcttc
    15481 tcgattttta ccgacacgat tgagttcgtc aaccagaaat tgaacccact ctgcaaagaa
    15541 aggacctctg tggagattga tccattccga atgaatatag acttcaggta aagccaaatc
    15601 tttagaaccc cagtctaaat agagaccttc tgcaatgacc agcataatca aaagatgggc
    15661 atagtctgat gaagccactg ccgaatacat tagatcctga aaggcttttg ttacagggtg
    15721 caaagtcact tctagatagt cattctctgc tacttttaac tctttaaaag ccttttggaa
    15781 ataaccatct tcatctgctt caagaaagcc tagttgcttg gcaaaacgaa gcttggattc
    15841 aagtttatct gcgtgagcta cgcaggcacc cagcatggat aagaaggcat caaagaagtg
    15901 ataatcttga atcagatagt cctttaagac cttattctca attgtccccg caaaaagttc
    15961 cttaacaaaa cgatgattga ttgcagcctg ccaatccttc tgactgcttt ttaataattc
    16021 tccaacagtc aaacctggct gaaatgcata gtcttgtgtt tccatattta cttctcctct
    16081 ctttacttgt tagtaattaa taaaacacca agaaatatca agcaaaatcg taattccact
    16141 tgatcctttt aaagcacatc gagagcattt gcagagagct aactaaacaa gcctatccag
    16201 tttatataaa caaaaaactc caattacaat caagaattag agttgactta caagattaga
    16261 tcgttcattt cgtcatacga aaaaacgttt cacatttccc ttcgccagtc ttaactgtat
    16321 caggttcaat gggtatcatc tcagcttaaa gcaccccaaa tgtctctatt atttaattac
    16381 tgaaccagta tagcaaaaaa tgaaagccct agcaagatat ttgaccgaaa aatatcttta
    16441 tatatagtag attgaaacta gaatagtaca catctacttc taaaacattg ttaaaaatcg
    16501 atttaactgt cctgattgat ttgtcctgtt tttattccat tttactatgg ttttcgatag
    16561 cgatttattc ttccaataca cgaagaaaaa cctccacatt cagtggaggc aatctctttt
    16621 atcaatacaa ttttaagtca cgagggtcaa ctgggaaagt tgggttgtat gggttgtgac
    16681 ggagtttgaa gtgtttaaca tcttcaatag tctgagttcc agacaactgc ataactgtct
    16741 tcaattccgc attcaagtgt tcaaagactt gacgcacacc aacactaccg ccgagagcca
    16801 agccatagat aaccgggcga ccaatagcta ccaagtctgc tcctgaagcc aaggctttaa
    16861 agacatgttg accacgacga acaccagagt caaagacaat tggcacacgt ttatcaactg
    16921 cttctgccac ttcttgaagc gagtcaaagg cagctggtcc accgtcgatt tgacgaccac
    16981 cgtggttggt tacccagata ccagaagctc ctgcagcaag cgaacgttca acgtcctcac
    17041 ggcattgtgg tcccttgaca tacacaggaa gtcctgagta ttcagcgata aattctacat
    17101 cacgtggaga caagcgttgt ttagctgatt tgtaaacaaa gtccattgat ttaccagcac
    17161 cttctggcag gtattcttca acaatcggca tgccaactgg gaagacaaaa ccattacgct
    17221 tatccacttc acgattcccc cctacagtag catctgccgt caagacaatc gctttataac
    17281 cttcagcctt cacacgatcc atgatgtggc ggttgatacc gtcatcctta ctaaagtaaa
    17341 attggaacca atggggtgtc ccttgaaggg cttcagaaat ctctggaagg tcaacagtag
    17401 agtaagaact ggttgtataa agagaaccaa actcatgcac accacgcgca gtcgccactt
    17461 ccccctgttc attcgctaat ttatgggccg caacaggcgc cataatgatt ggtgaagata
    17521 gtttttcacc tgcaaattca atctctgtac ttggattttc aacatcgcaa agtgtatgag
    17581 gaacgatgag tttgtggtta aaggcgcgga tattctctct taaagtgaaa gtatcttccg
    17641 ccccactagc gatatagcca aatgctgctt taggaataac ttgttgcgcc attggctcca
    17701 aatcataggt attgatgaag tctacatgac cttctgcatt gcttgttttg tatgacataa
    17761 aatgccctcc ttgattaagt aagcgtttgc tttttactac acaactataa taactctttt
    17821 ttcaatcatt ttcaagagtt ttgcttaaaa accatcttat tttttcatac aatatactag
    17881 ccctactttc cttaaactct aaaccttagt ctatattaag tgaatcgttg agattttttg
    17941 ctgccaggca tttgaactac ttttttattt gcggattcta tctactaata ctataaaaaa
    18001 acaagtgaat aagacaccag aacatcctct aataggacct atggacttat atcagtccca
    18061 tatatactgt ttaagcaaga tactatccta gttgacgcta acttcctatc ccacttatta
    18121 attttttatt tatagtgaat ctgaacaaat caattgggga atccaagtca atttctagta
    18181 ctttttgaac agtttcagcg tactatcgta aaatgaaata aaacatgcac aaattgctta
    18241 gggaatttaa accaatttct aacaatgtct tagaaatcaa agtgtactat ttcaacttca
    18301 atatactaca cttcattttc tccttaaatt cagtctcttt ttgaatcaaa aaatcccctg
    18361 gtaagagcca gaggataaga atttatttca ttgttgggaa gagcaataca tcacggatag
    18421 ttgttgtatc agtgaggagc atgcagagac ggtcgatacc gattcccaaa ccacctgttg
    18481 gtggcatacc gtattcaaga gcttcaatgt agtcatagtc gattcctgtc gcttcatcat
    18541 caccaagttc tttggcttta gcttgggctt caaaacggct aagttggtcg attgggtcgt
    18601 tcaactcagt aaaggcatta ccgtactcct tagtcatgat aaagagctcg aaacggtcag
    18661 taaagcgttg gtcttcagga tttttcttag cgagtggaga tacagctact ggatgtccat
    18721 agacaaaggt tggttggatt aaagtttctt caacaaactc ttcaaagaag gcattgatga
    18781 tgtgaccaac ctcagtgtag tgtttctcaa ctggaacttt cttctcagca gcgatagctt
    18841 tagcttcttc caaagtcatg tcttgccaga aatcgacacc agtaatttct ctgatagcat
    18901 ccaccatatg aacacgctta aatggttcgt taatcttgat ttcagtacct tggtagttga
    18961 ctgggccatc acctttgact gatttagcag cgtgttggat aatgccttca gtcaagtcca
    19021 tgatgtcttg gaagtctgca taagcttggt aaacttcgat agaagtgaac tcagggttat
    19081 gagtagcgtc cattccttcg ttacggaaga tacggccaat ttcatagaca cgttccatac
    19141 cacccacgat aaggcgtttt aagtgaagct cagtcgcgat acgaagcacc atgtcaatgt
    19201 tttgggcatt gtggtgggtg ataaatggac gggcagcagc accaccggct tcattatgaa
    19261 gaacaggtgt ttccacttca aggaatcctt tttggtcaag gtaacgacgg atttcagaga
    19321 tgatttttga acgagtgaca aagcgttcaa agctttcacg attagaaatc aagtcaaggt
    19381 aacgtttacg gtaaattgtt tcaacgtctg tcaaaccatg gaatttctca ggaagaggac
    19441 gaagagcctt agacaagtgt gtgatgtggg ttgccttgat agagagttct cccatatccg
    19501 tacgcatcac ttcaccttcg acaccaagga agtcaccaag gtctgctttt ttgaagattt
    19561 cgtagttttc ttcaccgaca gcatccttac gaacgtagat ctgaatctgg ccttcgcggt
    19621 cttgaaggtg ggcaaaacca acttttcctt taccacgttt ggttaccaag cgtcctgcga
    19681 tagtagctgt ttcgttttta tcgtgtaatt gttctttatc gaggttggta tatttatctt
    19741 ttaattcttg tgaatttaca gtacgttcaa aacgttttcc gaaaggatcg attccttgtt
    19801 cgcggagcgc agccattttt tcacggcgaa cgatctgctg gtcatttagt tcttccatat
    19861 gttctgtaga catgggatcc tcctagtttt actcaaaatt gaatacgatg agtcattttt
    19921 tgcgatactc ccattttatc ataaataagc aagaaattca cggataatct ttaaaaacta
    19981 aaaagaacct gacgctaaaa tcactggaaa gaagtgaaag tatctcccgc cccactagcg
    20041 atatagccaa atgctgcttt aggaataact tgttgcgcca ttggctccaa atcatag
//
LOCUS       DAVLBE010000032        19638 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.032, whole genome shotgun sequence.
ACCESSION   DAVLBE010000032 DAVLBE010000000
VERSION     DAVLBE010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19638)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19638)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19638
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.032"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(166..780)
                     /locus_tag="VXB91_001291"
     CDS             complement(166..780)
                     /locus_tag="VXB91_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HEV0470740.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAIVGEDAEEEEEEIIERL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(1595..1864)
                     /gene="rpsO"
                     /locus_tag="VXB91_001292"
     CDS             complement(1595..1864)
                     /gene="rpsO"
                     /locus_tag="VXB91_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HEV0470741.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            complement(2005..2634)
                     /locus_tag="VXB91_001293"
     CDS             complement(2005..2634)
                     /locus_tag="VXB91_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HEV0470742.1"
                     /translation="MKLAVIAANGQAGKAIVEEVVKRGHEVTAIVRSENKSQAESIIK
                     KDLFELTKDDLTGFDAVISAFGAYTPDTLPLHSKSIELFNQLLAGTQTRFLVVGGAGS
                     LYIDETKTTRLLDTSDFPEEFKSLAKAQADELDLLRTKNNLNWTFVSPAVDFIPDGEK
                     TGNYILAGEIFTTNEKGISQISYADYAIGLVDELEKGHHIKERISLLEK"
     gene            2872..3072
                     /locus_tag="VXB91_001294"
     CDS             2872..3072
                     /locus_tag="VXB91_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001826938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0470743.1"
                     /translation="MRRFYSHLPYYLVILFFYWPLYELFLLVVSDPLTLKELYINNLL
                     FFTPLVILIVSLLYSYRFRFSL"
     gene            3503..3826
                     /locus_tag="VXB91_001295"
     CDS             3503..3826
                     /locus_tag="VXB91_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HEV0470744.1"
                     /translation="MELQELVERSWAIRQAYHELEVKHHDSKWTVEEDPLALSNDIGN
                     FQRLVMTKQGRYYDETPYTLEQKLSENIWWLLELSQRLDIDILTEMENFLSDKEKQLN
                     VRTWK"
     gene            3884..5827
                     /gene="thrS"
                     /locus_tag="VXB91_001296"
     CDS             3884..5827
                     /gene="thrS"
                     /locus_tag="VXB91_001296"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HEV0470745.1"
                     /translation="MINITFPDGAVREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHEDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNTAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFEKKDLKNYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVDYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(5876..6850)
                     /locus_tag="VXB91_001297"
     CDS             complement(5876..6850)
                     /locus_tag="VXB91_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEV0470746.1"
                     /translation="MLDWKQFFLAYLRSRSRLFIYLLSLAFLVLLFQFLFASLGIYFL
                     YFFFLCCFVTILFFTWDILVEMQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLVLKQVQIEDLVKEIIRKYALFFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(6843..7520)
                     /locus_tag="VXB91_001298"
     CDS             complement(6843..7520)
                     /locus_tag="VXB91_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0470747.1"
                     /translation="MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            7676..8749
                     /locus_tag="VXB91_001299"
     CDS             7676..8749
                     /locus_tag="VXB91_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HEV0470748.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPREPTMLTSKNRLQLLDKLAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPAQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHQIIVQSTALGGIAQHDTFSWQIEDKHFVQLDKTNSDSQQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILEAGISSINDLASLKALEYIHHLFVQAQSLTPE
                     ERETLGRLTQLLIDTRYQAWKNR"
     gene            complement(8840..9142)
                     /locus_tag="VXB91_001300"
     CDS             complement(8840..9142)
                     /locus_tag="VXB91_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0470749.1"
                     /translation="MYLVIGIVLAFIVSFWKDNRSLWNPVLFLLSLISSYFYLSYLFY
                     KNGYENVQLAFYVFAFVLLPFLLFLSGIFLIYNGVILLKREGRSKPHYLSMLFDFY"
     gene            complement(9210..9647)
                     /locus_tag="VXB91_001301"
     CDS             complement(9210..9647)
                     /locus_tag="VXB91_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HEV0470750.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKKSKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTDIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            complement(9723..10565)
                     /locus_tag="VXB91_001302"
     CDS             complement(9723..10565)
                     /locus_tag="VXB91_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEV0470751.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADARQLGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQEEFDRLVTHPPCDIAVY
                     GHIHQQLLRYGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDDKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            10677..11327
                     /locus_tag="VXB91_001303"
     CDS             10677..11327
                     /locus_tag="VXB91_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HEV0470752.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRMHD
                     SFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNMDIAKQLYVEKIN"
     gene            11537..12172
                     /locus_tag="VXB91_001304"
     CDS             11537..12172
                     /locus_tag="VXB91_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HEV0470753.1"
                     /translation="MAIASGYLNSRLDKFVDWGPWTALVPFGLISVTNVGISMLSTRF
                     TGKLSKWENYFGIVNTILSGAIDYILGNKAAIITYPVTFLIYTFAIKKWKASQEGRPN
                     QMSQKQVKLAAIIISIIAFLFAFVTNYIGYGGKMNLLAYVTTIAFALSLIANALNALK
                     LTTQWGFWLIYNFVQLTKAGIQGNFANIGKYIFYILNAIGALFVWNDEEVR"
     gene            12303..12716
                     /locus_tag="VXB91_001305"
     CDS             12303..12716
                     /locus_tag="VXB91_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0470754.1"
                     /translation="MKKLYRIHFIAIAVIDLLLFAFFITRLETSFEWLLLSGLIFFLA
                     QGLLLFLLVVRLKHQFAEIYPQINKKIRFYYLGVLTIDFLFFVLLAFISSQRFSSLMP
                     IITACHSTFYYMTADYLRENYPDFYDKHISLWECL"
     gene            12735..13149
                     /locus_tag="VXB91_001306"
                     /pseudo
     CDS             12735..13149
                     /locus_tag="VXB91_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720030.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(13188..13631)
                     /locus_tag="VXB91_001307"
     CDS             complement(13188..13631)
                     /locus_tag="VXB91_001307"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HEV0470755.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKKGNRPAFTGAAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR"
     gene            complement(13661..15883)
                     /locus_tag="VXB91_001308"
     CDS             complement(13661..15883)
                     /locus_tag="VXB91_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HEV0470756.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRVIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYSSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            16294..16536
                     /locus_tag="VXB91_001309"
     CDS             16294..16536
                     /locus_tag="VXB91_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0470757.1"
                     /translation="MTRFEEIFEEYKNPQDTFFYPLVYKENTYEKTAISIFALLMLGV
                     CCLFLFSQQSYKKLVQYYANDQNLPSRITYSEYSDK"
     gene            16876..17505
                     /locus_tag="VXB91_001310"
     CDS             16876..17505
                     /locus_tag="VXB91_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEV0470758.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFRFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGPATTIAHEKAFNPFF"
     gene            complement(17628..19520)
                     /gene="pepO"
                     /locus_tag="VXB91_001311"
     CDS             complement(17628..19520)
                     /gene="pepO"
                     /locus_tag="VXB91_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HEV0470759.1"
                     /translation="MTRYQDDFYDAINGKWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVAAVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEEAWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
BASE COUNT         5761 a         4450 c         3629 g         5798 t
ORIGIN      
        1 ttcttatttc attttactat atttataaga atctcctaat caaatcaaaa gccactctac
       61 aatagagtaa ctttaagatt gtccatttat actcaatgaa aaagccccct gaaaatcaga
      121 gagctgattt gagctcgggc taaaatccta gtgaaacaaa aaaatctaca cgatcagaaa
      181 agtctctatc gtgccatttt catacatgat gtatagtcca agtagaatga atactaaggg
      241 cacaatgatt cgctcgtatt tttcaattgt ctcgaatatt aacggaatag aggataacac
      301 ccgactaatc tcgcaaaaga taattatgcc gattacaaac acaagcaagg ccacgagggt
      361 ctgtgaccaa tctaacgaag caaaataagg tatatagata cctaaattat ctccgccaga
      421 cgcaattgtc agcaatgtaa ctgtccaaaa cagttgattt gccttgcttt gttctaatct
      481 ttcaataatt tcttcctctt cttcttccgc atcttctcca acaattgcaa agcgaatccc
      541 taaatagata gggattaaac caagcaatcc aaccatccat tcttcaggca cgaaattaac
      601 gacataagca gcaactaaac tcgcccctac aagtaagcct gtgcctagat attgccccgc
      661 ataaatatgc catttctgtt tattctgtga tagctgtgca aataaaataa ttaaaataat
      721 taaataatcg atactggtgg aaatataaac accaatagca gatatgattg tctgtcccat
      781 aaaaaaaacc tcctgtatta gtcagtaata aatcagcaga ttttaggaga gcacagacac
      841 attaatttag ctatcgctag tgggtaatgt cgaacgtagg aaagcatttt actcctcctc
      901 aaaacgtagt tacaaagtaa tttctaactg gaattcagtg actacttcca tgtaaagtat
      961 aacatactat actttacttt gtaaagagtg ggctcttcta gggggcttgc atacagctac
     1021 tcggcttgaa aagccgagta actgcgcacc tttatggtgt aattagctga taccatttga
     1081 ggtttttgta gtctccaaaa ttgttaccga taaaacctca ataaaaaagc cctctgaagt
     1141 cagagagctg attttagccc gggctaaaat cctagtgaaa aagatgaaac tccttgtgct
     1201 catcgaacac tgtgtcattt ccctattttc atacggattt ttgacgccct tagcatcatg
     1261 attcttgcta gataaatcgt ttatagacta ggggacgagg tgaagatcgt acgaaacttt
     1321 cagtgaaaca aaaaaatctc cccgaaggga gaaaagctag tttattttac cttacagtgc
     1381 taggaaccgt aaccgaagat tatacttgag tatagcgagg taaggtgaca acgcaacaaa
     1441 gctacccaat ttagagtagc tttattatca agatatgctc aattgaacac ggcctaagca
     1501 cttggcaaaa aagataaaat ctcctagaaa ctgaagtttc ttcgtcaatt ttcctatttt
     1561 tgctttgtgt ttttgacggc ctttgtatct tgaattagcg acgaagtcct agagagttga
     1621 tcaactcacg gtaacggtta acgtcgtttt tacgcaagta tgcaagcaag ttacgacggc
     1681 gaccgatttt tttcatcaat ccacggtaag tagcgtggtc ttttttgtgt tgtttgatgt
     1741 gttcgttaag gtggttgatt tcccaagtaa ggacagcaac ttgaacctct actgaacctg
     1801 tatcaccttc gtgacgtgca tattgtgcaa tgatttcatt ttttttctct tttgagattg
     1861 ccatgatgtt tctccttttt atttggcttc atccgagtga caggttggca tgcctgtaac
     1921 caagaagaag ttatttgtct ttacgacaat ccctatttta ccaagattta aattttctgt
     1981 caaacattaa tactctcata gttattattt ttcaagtaaa gagatacgtt cttttatatg
     2041 atgacctttt tcaagttcat ctaccaatcc aatagcataa tctgcataac taatctggct
     2101 tattcctttt tcattagtag taaaaatttc tcctgctaga atgtagtttc ctgttttttc
     2161 accatcggga ataaaatcta cagcaggact gacaaaagtc cagttgagat tattttttgt
     2221 acgaagaaga tccaattcat ccgcttgagc ttttgctagt gacttaaatt cttcaggaaa
     2281 atcagacgta tctaaaagtc gtgtcgtttt tgtttcatct atataaagac ttcctgctcc
     2341 ccctacaact agaaaacgtg tctgtgttcc agcaagaagc tgattaaata gttcgattga
     2401 tttgctgtgg agcggtagcg tatctggtgt ataagcacca aacgctgaaa taacagcatc
     2461 aaatccagta agatcatctt ttgtcaactc aaataaatct tttttaataa tagactcagc
     2521 ttgacttttg ttttcagaac gaacaatagc cgttacttca tgtcctcgtt tgactacttc
     2581 ttcaacaatt gctttccccg cttgtccatt tgctgcaata actgctagtt tcatttttta
     2641 tacctctctt attgtaatta ttttagttac aacaattgtg acactcttaa taatcaatgt
     2701 caatagtttt gcttaattat tatcaaaata tttctaccaa gaaaactaac catgattcta
     2761 gtgaaaaaaa aatcttcttt gccaacaaat ttactttctt gttttaaaca tgctataata
     2821 atcatagcaa gagatctaag ttgtctgttt ttttaaaacg aggtgattat catgcgtaga
     2881 ttctattccc atctccccta ctatctggtc atattattct tttattggcc actttatgag
     2941 ttgttcttac tagttgtttc tgaccccctt acactcaagg aactctatat aaacaatctt
     3001 ctcttcttta cacctctggt aatcttgatt gtatcgttac tctatagcta ccgtttccgt
     3061 ttctcacttt gatggttagt tggtaacgga ctgctctttt actttactat cataaccttt
     3121 ggtgagttta tactaattta cttgctaatc tatgaaacag ttgctctggt gggcatggat
     3181 tctggtatta gcatcaagca tattctacaa aaaatgaaaa acaaaaaact ttcacaaaat
     3241 ccttgaaaaa tctcacaatc atgctataat aatccataga gacaagtcac ttagtccctt
     3301 tctactagag agtgcgtggt tgctggaaac gcataggaag tctaaactga tactactctt
     3361 gagtttttta tgaaaacata aaacggtggc cacgttagag ccaatcagag gtgtccctct
     3421 cttttgaggt acataaatga aggtggaacc acgttgcgac gtcctttcga ggatgtcgca
     3481 tttttttatt aggatactaa ttatggagtt gcaagaatta gtggagcgca gttgggcaat
     3541 ccgacaagct tatcacgaac tggaagttaa gcatcatgat tccaagtgga cggtagaaga
     3601 agaccccttg gctttatcta atgatattgg aaatttccaa cgactggtga tgacaaagca
     3661 aggacgctac tatgatgaaa caccctacac actggaacaa aaactttcag aaaatatctg
     3721 gtggctatta gaactttctc aacgtttgga tatagacatt ctgacggaaa tggaaaactt
     3781 cctctctgat aaagaaaagc aattgaacgt taggacttgg aagtagtctg atgataaaaa
     3841 atcaatgctt agaaactatg aaataataaa aaaggagaac atcatgatta acattacttt
     3901 cccagatggc gctgttcgtg aattcgaatc tggcgtaaca acttttgaaa ttgcccaatc
     3961 tatcagcaat tccctagcta aaaaagcctt ggctggtaaa ttcaacggca aactcatcga
     4021 cactactcgc gctatcactg aagatggaag catcgaaatt gtgacacctg atcacgaaga
     4081 tgcccttcca atcttgcgcc actcagcagc tcacttgttc gcccaagcag ctcgtcgtct
     4141 tttcccagac attcacttgg gagttggtcc agccatcgaa gatggtttct actacgatac
     4201 tgacaacaca gctggtcaaa tctctaacga agaccttcct cgtatcgaag aagaaatgca
     4261 aaaaatcgtc aaagaaaact tcccatctat tcgtgaagaa gtgactaaag acgaggcacg
     4321 tgaaatcttc aaaaatgacc cttacaagtt ggaattgatt gaagaacact cagaagacga
     4381 aggcggtttg actatctatc gtcagggtga atatgtagac ctctgccgtg gacctcacgt
     4441 tccatcaaca ggtcgtatcc aaatcttcca ccttctccat gtagctggtg cgtactggcg
     4501 tggaaacagc gacaacgcta tgatgcaacg tatctacggt acagcttggt ttgaaaagaa
     4561 agacttgaaa aactaccttc aaatgcgtga agaagctaag gaacgtgacc accgtaaact
     4621 tggtaaagag cttgacctct ttatgatttc acaagaagtg ggacaaggtt tgccattctg
     4681 gttgccaaat ggtgcgacta tccgtcgtga attggaacgc tacatcgtaa acaaagagtt
     4741 ggcttctggc taccaacacg tctacactcc accacttgct tctgttgagc tttacaagac
     4801 ttctggccac tgggatcatt accaagaaga catgttccca accatggaca tgggtgacgg
     4861 ggaagaattt gtccttcgtc caatgaactg tccgcaccac atccaagttt tcaaacacca
     4921 tgttcactct taccgtgaat tgccaatccg tatcgctgaa atcggtatga tgcaccgtta
     4981 cgaaaaatct ggtgccctca ctggccttca acgtgtacgt gaaatgtcac tcaacgacgg
     5041 tcacctattc gttactccag aacaaatcca agaagaattc caacgtgccc ttcagttgat
     5101 tatcgatgtt tatgaagact tcaacttgac tgactaccgc ttccgcctct ctcttcgtga
     5161 ccctcaagat actcataagt actttgataa cgatgagatg tgggaaaatg cccaaaccat
     5221 gcttcgtgca gctcttgatg aaatgggcgt ggactacttt gaagccgaag gtgaagcggc
     5281 cttctacgga ccaaaattgg atatccagat taaaactgcc cttggaaaag aagaaaccct
     5341 ttctactatc caacttgatt tcttgttgcc agaacgcttc gacctcaaat acatcggagc
     5401 tgatggcgaa gatcaccgtc cagtcatgat ccaccgtggg gttatctcaa ctatggaacg
     5461 cttcacagct atcttgattg agaactacaa gggtgccttc ccaacatggc tggcaccaca
     5521 ccaagtaacc cttatcccag tatctaacga aaaacacgtg gactacgctt gggaagtagc
     5581 caagaaactc cgtgaccgcg gtgtccgtgc agacgtagat gagcgcaatg aaaaaatgca
     5641 gttcaagatc cgtgcttcac aaaccagcaa gattccttac caattaattg ttggagacaa
     5701 agaaatggaa gacgaaacag tcaacgttcg tcgctacggc caaaaagaaa cacaaactgt
     5761 ctcagttgat aattttgttc aagctatcct agctgatatc gccaacaaat cacgcgttga
     5821 gaaataagag tctagcataa aagcctccaa tctggaggct ttttctcatc tatttttact
     5881 caaggactaa gttcacttga gcaaactgaa tccgcactgt cgttcctttt ccgacctcag
     5941 actcgatacg aatctggtgc cccagttctt cagaaatttt cttagataga taaaggccaa
     6001 gtccagagga ctgctgggtc aaacggccat tgtatcctga aaagccacgt tcaaatactc
     6061 ggaggacatc actgtttttt atcccgattc ccgtatcttt gatacaaagc tcttggtcat
     6121 ccatataaat ctccagacca ccttccttgg tgtacttgag actgtttgag atgatttgct
     6181 caataaccac tagcagccac tttttatccg tcacgatttc tttatcaagg tcatgtagat
     6241 tgacatttaa gcctttttga ataaagaaaa gagcatattt acgaattatt tccttgacca
     6301 agtcctcaat ttgaacctgc tttaagacca aatcatcatg gaaactttct aaacgcaggt
     6361 actgtaaaac taggttggta taagagtcga ttttgaaaat ttcctgttct agctgctgct
     6421 tcagttggcg gtcgaccact tctgcaacta agagttgact ggctgcaatg ggggtcttta
     6481 tctgatggac ccacaaggta tagtaatcca gcaaatccgt cagttttctt tctgcttttg
     6541 acctctgctg atagagttcc atctcacgcg cttctaattt ttctgctaaa gctatttcca
     6601 aaggagactt ggcttccctc tctccataga gaagttcctg gcgatagacc tgcatttcca
     6661 ccaatatgtc ccaagtgaaa aataagatgg ttacaaagca acacaagaag aaaaagtaga
     6721 ggaagtaaat tcctagactg gcaaataaaa actgaaagag taagacaaga aatgccaaag
     6781 aaagcagata gataaaaaga cgactacggg agcgcagata ggctagaaaa aattgtttcc
     6841 aatcaagcat gcttcaatcc gtaccctatt cctttcttgg tctcgataaa tcctaccaat
     6901 ccctgctcct ccaacttttt acgcaaacga gccacattga cagagagggt attatcatca
     6961 atgaaaaagt cactgttcca aagttcccgc atcaggtcgt cacgtgctac gatgttgcct
     7021 gcatgctcaa ataacacgcg taaaatctgg aattcattct tggtcaaatt caagacttgc
     7081 ccttgataat gtaaatccat ggatttggta ttgaggataa caccagcata ttccagcaaa
     7141 ctctcatcac gcccaaactc ataggaacga cgcaacaagc cctgaacctt agctaaaaga
     7201 acctgctggt caaaaggctt ggtcacaaag tcatccgccc ccatattgat tgccatgaca
     7261 atatccatag cctggtctct cgaagaaaga aacatgatag gtaccttgga aatcttgcgg
     7321 atttcctgac accagtgata accattaaac aagggcaaac caatatccat gaggaccaga
     7381 tgaggttccg actgaacaaa tagactcaaa acttccataa agtcttctac caggaccact
     7441 tcaaatcccc attcagagag cattttccca atctgttgac gaatgacctg atcatcttct
     7501 attaataaaa tcttgtgcat gcgcttctcc ttttccatta ttataacaga tttttccatg
     7561 ctagatggtc tgaaactgaa tttgaaatag cctgttttta gccagtgcaa acaggctatg
     7621 ctactagcta atttgaggga aatttgctaa gataaataaa aagaaaggag ctcttatggc
     7681 caatattttt gactatctga aagatgtcgc atatgattct tattacgacc ttcccttgaa
     7741 tgagttagac attctaacct taatagaaat cacctacctc tcctttgata atctggtctc
     7801 cacacttcct caacgtcttt tagatctagc acctcaggtt ccaagagagc ccaccatgct
     7861 tactagcaaa aatcgccttc aattattaga taaattggct caacacaagc gcttcaaaaa
     7921 ttgcaaactc tcccatttta tcaacgacat cgaccctgaa ctgcaaaagc aatttgcggc
     7981 tatgacttat cgtgtcagcc tcgataccta tctgattgtc tttcgtggga cagatgacag
     8041 tatcattggc tggaaggaag atttccacct gacctatatg aaggaaattc ctgctcaaaa
     8101 gcacgccctt cgctatttaa agaacttttt tgcccatcat cctaagcaaa aggttattct
     8161 agctgggcat tccaagggag gaaatctcgc tatctatgct gctagccaaa ttgagcaaag
     8221 tttgcaaaat cagatcacag cagtttatac atttgatgca cctggtctcc atcaagaatt
     8281 gacacagact gcgggttatc aaaggataat ggatagaagc aagatattca ttccacaagg
     8341 ttccattatc ggtatgatgc tggaaattcc tgctcaccaa atcatcgttc agagtactgc
     8401 cctgggtggc atcgcccagc acgatacctt tagttggcag attgaggaca agcacttcgt
     8461 ccaactggat aagaccaaca gtgatagcca gcaagtagac acaaccttta aagaatgggt
     8521 ggccacagtc cctgacgaag aacttcagct ctacttcgac ctcttctttg gcactattct
     8581 tgaggctggt attagctcta tcaatgactt ggcttcctta aaggcgcttg aatacattca
     8641 tcatctcttt gtccaagctc aatccctcac tccagaagaa agagaaacct tgggtcgcct
     8701 tacccagtta ttgattgata ctcgttacca ggcatggaaa aatagataat actcttgaaa
     8761 attaaatgta tacaaaacaa aagacctaga atacatactt tcatgtgcat tctaagtctt
     8821 tttaaataga atctaatagt caataaaaat caaagagcat tgagagataa tggggcttgg
     8881 aacgtccctc tcgcttcaac aaaatgaccc cattatagat taaaaagatg ccacttagaa
     8941 aaagcaaaaa aggaagtaag acaaaggcaa atacataaaa agctaactga acattctcgt
     9001 atccattttt ataaaaaagg taggatagat aaaaataact tgaaatgagg gataataaaa
     9061 ataatactgg attccacaaa cttctattat ccttccaaaa tgacactata aaggctaata
     9121 caattcctat aacgagatac atttcttact cctttaatag ctacatttta tcataattat
     9181 ccaaagaaaa aagagggcat ttatccctct taatccttca tctgactctc tgcatcggcc
     9241 acgacttttt ctagactggt ttgaccaagt tctgcctcca tagtcaactg aattctctcc
     9301 aatttttgat ccaaaacatc atgaatatga gctcctacag ggcaatttgg attcggattg
     9361 tcatggaaac tgaagagttg acctgtctta ccaagacatt cgaccgcctg ataaacatct
     9421 aaaagactaa tatccttaag gtccttgaca atatctgttc cgcccgttcc acgcgctact
     9481 gaaatcagct ctgccttctt caactgggac aagatctttc tgataatgac aggattgacc
     9541 ccgacactag cagccagaaa atcactggtc accttgcttt tcttcccctc gagggcaatg
     9601 attatcagca tatgagtcgc aatggtaaat ctacttggaa tttgcatcct cttctccttt
     9661 ttacgaggct accctgcctc tactcttctt tttctattat tatacccttt ttagttgtaa
     9721 tgtcaatcgt taccactttt caaccagtcg tctaactccc gatcgcaacc ctctttctga
     9781 gccaattctc tcaaaaattc ctgatgatga gtatggtgga tcccattgac cagactttca
     9841 tagtaaacct caaaataggg aagtctcagg tctttagcca gctgcaattc agctgccaca
     9901 tcgtaatcta cccgtcggaa gtccatatct accaggccct tgtcatcaaa ctccaaaatc
     9961 atatactggg cccgcaagtc cttccgtagc tgagcgtcca aaaagaaagg ttggccaatc
    10021 gaacccggat tgacaatcaa ttgcccacca gtcccgtaac gaagcaactg ctggtgaatg
    10081 tgtccataaa cagcaatatc acagggagga tgagtcacca agcggtcaaa ttcctcttgt
    10141 ttgccagtat gaatcaactc tcgcccccag ttcttatcag gcagatgatg gctaattccc
    10201 actgtcaaat ccccaaactg acgatgaatt tgaagaggtt gattgtggag cacttcaatt
    10261 tcttctaggg aaatttcctc taaaacatac tggcactggc gcaagagata gcgttgacta
    10321 gggcgagtac tatccaattc cttacggaca ccatgccaaa gactgtcttc ccagtttccc
    10381 aaaactctag ccgtaatcgg tagttgatcc aacaagtcca aaatccttct acgccctgtc
    10441 cctggcatga gaatatctcc caaaagccag tattcatcca ctcctagctg ccgagcatct
    10501 gccaaaacag cctccaaggc ggtggtattt ccatgaatat ctgaaagaag agctattttc
    10561 gtcatatcca tctcctcgtt ttttctcttg caataagtat aacataaaaa gtcacagcta
    10621 gagaaatcta gctttttttg atatactaga taaagatatt agacaagagg aaacgaatga
    10681 ccccaaacaa agaagactat ctaaaatgta tttatgaaat tggcatagac ctgcataaga
    10741 ttaccaacaa ggaaattgcg gctcgcatgc aagtctctcc ccctgccgta actgaaatga
    10801 tcaaacgaat gaaaagtgaa aatctcatcc taaaggacaa ggaatgtggc tatctactga
    10861 ctgacctcgg tctcaaactg gtctctgagc tctatcgtaa gcaccgcttg attgaagttt
    10921 ttctagttca tcatttagac tatacaagtg accagattca cgaggaagct gaggtcttgg
    10981 aacacactgt ctctgacctg ttcgtggaaa gactagataa actgctaggt ttccctaaaa
    11041 cctgccccca cggaggaact attcctgcca agggagaact cctcgttgaa atcaataacc
    11101 tcccactagc tgatatcaag gaagctggcg cctaccgcct gactcggatg cacgatagtt
    11161 ttgacattct ccattatctg gacaagcact cacttcacat cggtgaccag ctccaagtta
    11221 agcagtttga tggcttcagc aataccttca ctatcctcag taacgacgag gatttacaag
    11281 tgaatatgga cattgcaaaa caactctatg tcgagaaaat caactaattt ctcaagtccc
    11341 ctaccaaccc tgaaagtttt attttcaggg ttttatttct atcattttat tttactttca
    11401 tttggtggta gaatatttga aaaaaaatgg gagaatattt gaaaaaaaga aaggtagttt
    11461 aacctatgaa aaaatcacta aaaatttttg ctacatctaa atagtttgac ctcttcgggg
    11521 ttgctttggt cgttggattg cgattgcatc tggttacctc aactcacgcc tcgataaatt
    11581 tgtagactgg ggaccatgga cagctcttgt accctttgga ttgatttccg taaccaacgt
    11641 tgggatttcc atgttgtcca ctcgtttcac ggggaaatta agcaaatggg aaaattactt
    11701 tggtattgtt aataccattt tgtccggtgc tattgattat atccttggaa ataaggcggc
    11761 catcattacc tatcccgtca ccttcctcat ttataccttt gctataaaga aatggaaagc
    11821 ttcgcaagaa ggcagaccca accaaatgag ccaaaaacag gtaaaattgg cggccatcat
    11881 catttccatc atcgccttcc tctttgcctt tgtgaccaac tatatcggat atgggggcaa
    11941 gatgaatctc cttgcctacg taacaactat tgcctttgca ctgtccctca ttgccaatgc
    12001 tttgaatgca ttaaaactaa caactcagtg gggcttttgg ttgatttaca atttcgttca
    12061 gctgacaaaa gctggtattc aaggaaactt cgccaatatc ggtaaataca tcttttatat
    12121 cctcaatgca atcggagctt tatttgtctg gaatgatgaa gaagttagat aatagaagga
    12181 aactcaaata aagaatacta gccaacttaa gagaatctcc cctctgctat ttttatcatt
    12241 ttagttgtaa ctcccattct tttagagtag aatgaagtta gataaaagag ggaggtcttg
    12301 tcatgaaaaa actctataga atccatttta tagcaattgc agttattgat ttgctactat
    12361 ttgcattttt tatcactaga ctcgagacat cttttgagtg gctcttgctc tctggtttaa
    12421 ttttcttcct tgctcaagga ctcctgctat ttctcttggt cgtccgactc aaacatcaat
    12481 tcgctgagat ttatcctcaa atcaataaaa agattcgctt ctactattta ggggttctca
    12541 ccattgattt tctatttttt gttctcttag ccttcattag ttctcagcgt ttttcatctc
    12601 ttatgccaat catcactgct tgccattcta ctttttatta tatgacagct gactacctaa
    12661 gagaaaacta tccagacttt tacgacaaac acatctcttt atgggagtgt ctctaaggaa
    12721 aaggaggttt tagcatgaaa aaaatcatct tcatcaaaac cattcaactc cttgtcattg
    12781 atggaatcat gctggtattt ttgacattta aaagggggcc ttacttggga ctggattttg
    12841 atttatagtg gttggctcat tttctttcat cccgtgctat tgacctatct ttcaaaccaa
    12901 ctttgtgacc actttagtca actctattcc cagattagac cgagattctg gcgttttgct
    12961 ttacaaattc tcctatggga tagcctgatg attctctcct tggtgtcttt aagtgatatt
    13021 ccacttttcc ttcagggaac tctcctcatc ctaggacatc tcatcccttc ctatcgcatc
    13081 tgccaaagcc tgaaaagaga cttcccccaa gcatatcaag aaccgatttc tttttggagt
    13141 attttatgat cgatgagaaa gaccaagccg actgggcttg gtctttctta tctcttttta
    13201 gtatctagga taatggtaac aggtccgtta ttaaccagct caacctgcat atctgctcca
    13261 aagatacctg tctgaacggg cacttcttgc gctaattttt gattgaaagc atcatagaag
    13321 tctgatgcca tatcaggttt agctgcccct gtaaaggctg gacgattgcc tttcttagta
    13381 tccgcaaaga gggtaaactg agaaatagag aggatttctc cttcaatatc tttgacagac
    13441 aggttcatct tgccttctgc gtctgaaaaa atccgcatat tgaccagttt tctcacagca
    13501 tagtccaaat cttcctcttg gtcctctggt ccaacaccaa ccagcaataa aagtccctga
    13561 ttgatttttc cctgaatctg gccttctata ctcacttggg cttttttaac ccgttggata
    13621 atgattttca taatagcctt tctagtaaga gctaggacaa ctagccgttg gtccgtttga
    13681 cagagtaaac ttctggcaca ctcttaattt tatcgacaac cgtggtcagt gtagagaggt
    13741 tggcaatacc gaaggacaca tggatattag caaacttcat atccttggtt ggttgggcat
    13801 tgaccgttga aatattcttg gttgtatttg aaagaacttg cagtacatcg ttcaacagtc
    13861 ctgtacggtt gagaccgtag atatcgatat gggccatata ctccttattt gagctagagt
    13921 actggtcttc ccattccaca tcaaggagac gttgctcgta gttttcttgg gcacgcaggt
    13981 tcatacagtc cacacggtga atagccacac cacgaccctt ggtaatgtag ccaacaatat
    14041 cgtcaccagg cacggggtta caacacttag caatccgcac taggagacca gaagcacctt
    14101 caataaccac tcccccctca tgcttgacct tgagagtttc tttattttca accttgacct
    14161 cgccaccttt gacaagctcc tctgcctcag ccttggcctt ggcacgctct tcctcacggc
    14221 gttccttttc agtcagacgg ttaaagacgg taatcgcacc gatttcccca aaaccaatgg
    14281 ccgcaaagag ggagtcttct gtcttgtaac tggtcttttg cagaacttga tccatgtggc
    14341 gcttgtccat aaatttattt gccacatagc cattttcttg gaactgagcc atcagcatct
    14401 cacgaccctt gttgacagac aattccttat cttggttttt aaagaactgg cgaatcttat
    14461 tgcgcgcctt gctagtcttg accatattga gccagtcacg gctaggtcca aaggagttcg
    14521 ggttggcgat aatttcaacc tgatcccctg tctttaactt ggttgtcagt ggaaccatgc
    14581 ggccattgac cttggcacca gttgcttttt caccgacctt ggtatggatt tcgtaggcaa
    14641 aatcaatcgg tcctgaatct ttgggaaggg aacggacagc tccatctggg gtaaaaacgt
    14701 aaatctcctc agccaaatag ttttccttaa cagagtccac aaattcctta gcatcatcag
    14761 cctggtcttg gagctccatc atctccttga tccagttcat tccaatagct gattccttgc
    14821 tgttaacttg cccctttata cctttcttat aagcccagtg agccgcaacc ccgtactcag
    14881 ccacctcgtg catttccttg gttcgaatct ggaattcaat cggccctttt ggtccataaa
    14941 cagtcgtatg gatagactga taaccattgg ccttgcggtt ggcaatatag tctttgaagc
    15001 gacctggcat cggtttccaa aattcatgca cgtaaccaag catggcataa acatcacttt
    15061 gggtatctaa aatacaacga atagcaatca gatcatagat ttcctcaaac cgttttctct
    15121 tgtcctgcat tttgcggaaa attgagtaaa tatgcttggg acgaccataa atcttccctt
    15181 tcaagtgacg ttctgtcgta tactcctcta attttgtgac tacctcatcc accaaggcct
    15241 cacgctccct gcgcttttcc ttcatcatat gggtaatctt gtaaaactcc gttggattga
    15301 gataacggaa agacaagtct tctaattccc atttgacact ggaaatcccc aaacgatggg
    15361 caagtggggc atagatttcc atggtttctt tggaaatacg ctcctgcttg tcttttcgaa
    15421 gatgtttcag ggtccgcata ttgtgcaagc ggtcagacag tttgaccaaa ataacgcgga
    15481 tgtcctcaga catggccatg agcatcttgc gatgattttc cgctaattgc tcctcgatcg
    15541 atttgtactc gaccttgcca agcttggtaa ctccgtcaac aatcacccgc acatcaggac
    15601 caaactctct ttccaaatcg tccaaggtcg catctgtatc ttccaccaca tcatgcaaga
    15661 atccacaagc tactgttaca gcatccagct ttagcttagc taaaatacct gccacttgga
    15721 tagggtgaat gatataaggc tcgcctgatt tgcgatattg accactgtgg cattcaacag
    15781 catagaccaa ggccttatgg acaaaatgaa catcctcttc cgttaaatat tctttggtta
    15841 aagcgacaac ttcttcgcct gttaaattca cttctttcgg catctctact ctccaattct
    15901 tcctaccatt ttatcacttt tttaagaata tgaaaactag attggaacag aataagaaaa
    15961 aaataattca aaattgcttg ataattctga attattggcc cataatatac tacgaagtta
    16021 gattttaaac ttaggtgata gaaggagaga tagaagaacg gaaaccatat tgtaacccaa
    16081 agactttctg atttccccaa ttccattgaa gatacgaaag ataaacggtg gaactcgtat
    16141 cacatacact ggtaccttga ctggattttg gaattaatac tcaatgaaaa tcaaagagca
    16201 aactaggaaa ctagccacag gttgctcaaa gcactgcttt gaggttgtag ataagactga
    16261 caaagtcagt cacatatata cggcaaggcg acgttgacgc ggtttgaaga gatttttgaa
    16321 gagtataaaa atcctcaaga tactttcttc tatcctttag tttataagga gaatacctat
    16381 gaaaaaactg ctatttctat ctttgctctc ctaatgttag gagtttgctg cctgttccta
    16441 ttcagccagc aaagctataa aaaactcgtt caatactatg ctaacgacca gaacctgccc
    16501 agtaggataa cttatagtga atatagcgac aaatgagaag ccaactacgg tagcactcta
    16561 aacatcacgt ctatcaaaca agctaatgac ggagtttatg caacctatga agggcaattg
    16621 acacctttcc aatattgata aattgataac cagcctgtct tcatctagtc atgctggttt
    16681 ttaagttcat tttaaatcct tacctattct ccctaactgt gctatactta atttatactc
    16741 aatgaaaatc aaagagcaaa ctagaaagct agccgcaggc tgttcaaagc actgctttga
    16801 ggttgcagat aaagttgacg cggtttgaag agattttcga agagtattag tacattcttt
    16861 gagattggag ttagtatgaa aatccataaa accgtgaatc ctgttgccta tgaaaatacc
    16921 tattatctag aaggcgaaaa gcacctcatc gtcgtcgatc ctggtagtca ttgggaagcc
    16981 attcgtcaga caatcgagaa gatcaacaaa ccgatctgtg ctattctctt gacccacgcc
    17041 cattatgacc atatcatgag tctggacttg gttcgcgaga cgtttggcaa tcctcctgtc
    17101 tatatcgcag agagcgaagc cagctggctc tacactcctg tcgataatct ctccggtctc
    17161 cctcgccacg atgatatggc agatgtggtc acaaaacctg cagaacacac ctttgtcttt
    17221 cacgaagaat accaactaga ggaatttcgt tttaaggttc taccgacccc agggcactct
    17281 atcggtggtg tttccctagt ctttcctgat gctcacctag tcttgacggg agatgctcta
    17341 ttccgcgaaa ctatcggacg gaccgacctt ccgactggta gcatggagca actccttcat
    17401 agtatccaga cccaactctt caccctacca aactacgatg tctatccagg acatggtcca
    17461 gctactacta tcgctcacga aaaggccttc aatccctttt tctagcaaga tgatgacaat
    17521 cgaaatttaa gtaaactatc cagcaaatct ttctattaca aaaggcatcc tatcaaggtt
    17581 ttcacacgtg attggatgcc ttttttctga tgactagatt ttttgtatta ccaaataatc
    17641 acgcgctcct ctggtgaacg ccacattccg tctccttctt tgacatcata ggttgtaaag
    17701 aaatcgtcga agtttggtac ttgcacattg acacggagtt tggctggtgc gtgcacatcg
    17761 acgctagcca aaagtttcat aaattctggt cgacctttca tgcgccagat gcgaccgaag
    17821 ttgtagaaga actcttctgc tgagaagtct gcttctctct tagctgcttc aagcgctgct
    17881 gcgattcctc ccaagtcagc cacgttttct gatacagtca atttaccgtt aatggttgct
    17941 ccataagaat cctgtccatc aaattggtca atgacttttt gtgttttctc cttgaaggca
    18001 gcatagtcgc tctctgtcca ccaatccttg aggctaccat tttcgtcaaa ggaagccccg
    18061 ttagtatcaa aggcgtggga aatttcatgg gcaatcactg ccccaatacc accgtagtta
    18121 gcagaagatg actgatgcaa gtcatagaaa ggcgcctgta aaatggccgc tggaaagaca
    18181 atcaggttct tctgaggatt gtagtaggca ttgaccatat gagcaggcat gccccattcc
    18241 ttatagtcta caggctggtt ccacttactc caactgtgct tgatttccac acgcgcaaag
    18301 gctagagcat tctcaaaaag actggcagtt tcattcacta ccttatcctt gtaacgtgca
    18361 ggcaattctt ctggatagcc aatataaggt ttgatcacat tgagcttcac gatagcctgt
    18421 ttacaggttt ctggagtgag ccagtcattc ttaagcagac gctccttata gacatcaatc
    18481 atggttgcca cttttttctc cacatccgcc ttggcttctg gagagaactt ctcacgggcg
    18541 taccaaagcc ccagggcttg cttgaaaggt tcctgtgcta gatgataagc tgctttgacc
    18601 ttatcttttg cctctggaac tccagaaagg gcacggctgt aggcaccaga caaaacacgg
    18661 atatcctctg ttaaatagct ggttgaaaga ttgacaacac tcaaaatcaa ggttgcttta
    18721 aggagagacc aggcttcctc actgtaaaat tgctctgctg cttgccagaa acgttcctcg
    18781 tctacaataa ccttgtctgg taattgccca ataactgctt tgaagaagtc atccaaaggt
    18841 agggcaggcg cgaatttctt gaaatcttcg taagaatatg gatgatagag tttagcatat
    18901 tctgaacttt cttcattaga gagcaccact gccgcaactc ggcggtccaa ttcaagtctt
    18961 ttttctagca agtcttcaat ttcttcatca gagaaatcat aagccttgag gagatttgcg
    19021 ctgctttctt tccaaagagt caagagctct tcgcgctgag gatgttcttc tgcatagtag
    19081 gtcgtatctg gcaagattgt gcttggagcg ctagcccata gaacattgat tctagcatcc
    19141 ataaagtctg gcgatacacc aaaaggaagg aagtttggtt ttcctgcaag ctcaaactct
    19201 gctagtttag ctgtaaaatc cgcaaaagtt tccaattctt ggaattcttt aaggagtggt
    19261 aagacaggtg tgataccgtc agcttctctc ttgtcaaaat cacgaactag gcggtggtat
    19321 ttgacaaagt tttccaagat agcatcctca ggcacttctt cacctgctaa ccacttgtct
    19381 gttgtcgcca gcatcaggtc ttcaatttcc tggtctaaat caacaaaacc tcctgtttga
    19441 gacttatctg ctgggatttc agctgtctgt tgccattttc cattgatagc atcataaaaa
    19501 tcatcttgat aacgtgtcat cttgttctcg ctttcatttg tatttgcatt tatcttaaca
    19561 aaaatcacta gggaatgcaa ttaataacca tttaactatt attttttagc tattataaaa
    19621 aatctttcca tgataaaa
//
LOCUS       DAVLBE010000033        18757 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.033, whole genome shotgun sequence.
ACCESSION   DAVLBE010000033 DAVLBE010000000
VERSION     DAVLBE010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18757)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18757)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18757
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.033"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(85..894)
                     /locus_tag="VXB91_001312"
     CDS             complement(85..894)
                     /locus_tag="VXB91_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEV0470760.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKHDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDRFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNIPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYMTPPSKEMQEWYSHSIKAYRKN"
     gene            complement(896..1699)
                     /locus_tag="VXB91_001313"
     CDS             complement(896..1699)
                     /locus_tag="VXB91_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEV0470761.1"
                     /translation="MKQLTVEDAKQIELEILDYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYELLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPMDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRPVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSGTFDKT
                     IDLPFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            complement(1709..3196)
                     /gene="tacF"
                     /locus_tag="VXB91_001314"
     CDS             complement(1709..3196)
                     /gene="tacF"
                     /locus_tag="VXB91_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HEV0470762.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNRTFSSLFYLCIACTILTTAVYILA
                     YPLFFTDNPIIKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGGILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNRIVAPEYYLLTTML
                     SEASLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFVYPVDMVINLP
                     FLINTGLIILLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            3532..4239
                     /locus_tag="VXB91_001315"
     CDS             3532..4239
                     /locus_tag="VXB91_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HEV0470763.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVSHAEDLVDKYLPLYKERIIITKGGADRNTSIKKIIEAIDAYRPL
                     TPEDIVVTHDSVRPFITLRMIQDNIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            4244..5266
                     /locus_tag="VXB91_001316"
     CDS             4244..5266
                     /locus_tag="VXB91_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEV0470764.1"
                     /translation="MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPESEIVVIGRHWEKLELFSFAKECYITDNI
                     PEELAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLI
                     LVGSSRSGRIDFKNAIQMMEVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            5283..6152
                     /gene="licA"
                     /locus_tag="VXB91_001317"
     CDS             5283..6152
                     /gene="licA"
                     /locus_tag="VXB91_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HEV0470765.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIESAITLDSTSI
                     KTKFDKIAPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGEDFGDYGVNRYQRA
                     VKGLASYGGSDEK"
     gene            6142..7020
                     /locus_tag="VXB91_001318"
     CDS             6142..7020
                     /locus_tag="VXB91_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HEV0470766.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAAAHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFTAVANGQL
                     LGLMIVFAAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAVVFLGAPLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            7032..7721
                     /locus_tag="VXB91_001319"
     CDS             7032..7721
                     /locus_tag="VXB91_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HEV0470767.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQDIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYVSGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     RKLEEILKNEN"
     gene            7817..8665
                     /gene="dprA"
                     /locus_tag="VXB91_001320"
     CDS             7817..8665
                     /gene="dprA"
                     /locus_tag="VXB91_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HEV0470768.1"
                     /translation="MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDV
                     LAEFEF"
     gene            9554..10597
                     /locus_tag="VXB91_001321"
     CDS             9554..10597
                     /locus_tag="VXB91_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HEV0470769.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIVARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGYNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEYFFQYIKDKEAKEK
                     EKANKFDTESEEQ"
     gene            10764..12851
                     /gene="topA"
                     /locus_tag="VXB91_001322"
     CDS             10764..12851
                     /gene="topA"
                     /locus_tag="VXB91_001322"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HEV0470770.1"
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNNEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQKGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMVVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEEKIK"
     gene            12957..13316
                     /locus_tag="VXB91_001323"
     CDS             12957..13316
                     /locus_tag="VXB91_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HEV0470771.1"
                     /translation="MRLIYLIIGFLSLALAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQTYVADFRETKSITRERKKKIIVSIYILMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            13409..14041
                     /locus_tag="VXB91_001324"
     CDS             13409..14041
                     /locus_tag="VXB91_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HEV0470772.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDICLTAQAGSQGVVFGALTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQPEAIDWLSQAGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLDNRQTFIDQVGVTQLHGTKVVF"
     gene            14085..14741
                     /locus_tag="VXB91_001325"
     CDS             14085..14741
                     /locus_tag="VXB91_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HEV0470773.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPHVHMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            14760..15392
                     /locus_tag="VXB91_001326"
     CDS             14760..15392
                     /locus_tag="VXB91_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001010941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HEV0470774.1"
                     /translation="MNFQLAKYSLLKKFLENIGFTTLEEYGAIFKYLIENVKTDRQII
                     CSPHCHDDLGMAVANSLAAVKNGAGRVEGTINGIRERAENAALEEIAVALNIRQDYYQ
                     VETSIVLNETINTSEMVSRFSGIPVPKNKAVVGGNTFSHESGIHQDGVLKNPLTYEII
                     TPELVGVKIPLGKLSGRHAFVEKLRELALDFTEEDIKPLFAKFKALADKK"
     gene            15420..15854
                     /locus_tag="VXB91_001327"
     CDS             15420..15854
                     /locus_tag="VXB91_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase I"
                     /protein_id="HEV0470775.1"
                     /translation="MVAGTMVENPEGFHFDDLQLQTHADNDIEALVSLANMDGEKVEF
                     NATGQGSVEAIFNAIDKFFNQSVRLVSYTINAVTDGIDAQDRVLVTVENRDTETIFNA
                     AGLDFDVLKASAIAYINANTFVQKENAGEMGRSVSYHDMPSV"
     gene            15866..16903
                     /gene="leuB"
                     /locus_tag="VXB91_001328"
     CDS             15866..16903
                     /gene="leuB"
                     /locus_tag="VXB91_001328"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HEV0470776.1"
                     /translation="MAKKIVALVGDGIGPEIMEAGLEVLEALAEKTGFDYEIDRRPFG
                     GADIDAAGPPLPDETLKASREADAILLAAIGSPQYDGAAVRPEQGLMALRKELNLYAN
                     IRPVKIFDSLKYLSPLKPERISGVDFVVVRELTGEIYFGDHILEERKARDINDYSYEE
                     VERIIRKAFEIARNRRKIVTSIDKQNVLATSKLWRKVAEEVAQDFPDVTLEHQLVDSA
                     AMLMITNPAKFDVIVTENLFGDILSDESSVLSGTLEVMPSASHSENGPSLYEPIHGSA
                     PDIAGQGIANPTSMILSVAMMLRDSFGRYEDAERIKHAVETSLAAGILTRDIGGQAST
                     KEMTEAIIARL"
     gene            16900..17169
                     /locus_tag="VXB91_001329"
     CDS             16900..17169
                     /locus_tag="VXB91_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HEV0470777.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKFKARRRTWRIQEKILLIL
                     ALTCGGFGAWLAGITFHHKTRKWYFKTVWFLGMVTTLVALYFIWR"
     gene            17173..17532
                     /gene="leuD"
                     /locus_tag="VXB91_001330"
     CDS             17173..17532
                     /gene="leuD"
                     /locus_tag="VXB91_001330"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HEV0470778.1"
                     /translation="MAGSSREHAAWVLADYGFKVVIAGSFGDIHYNNELNNGLLPIVQ
                     PREVREKLAQLKPTDQVTVDLEQQKIISPVEEFTFEIDSEWKHKLLNSLDDIGITLQY
                     EELIAAYEKQRPAYWQD"
     gene            17694..18317
                     /locus_tag="VXB91_001331"
                     /pseudo
     CDS             17694..18317
                     /locus_tag="VXB91_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002276310.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="translation factor (SUA5)"
     gene            18483..>18757
                     /locus_tag="VXB91_001332"
     CDS             18483..>18757
                     /locus_tag="VXB91_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0470779.1"
                     /translation="MNKRKVSLEDFYKWYSLNKEELLNKATVGEKFNDKLKEEFLQEW
                     PLDRILTMSIDEYVIGKGQQNKSLCYALEKGKYKNLFLGISGGSASK"
BASE COUNT         5898 a         3207 c         3965 g         5687 t
ORIGIN      
        1 attgtgggaa tatgtatttc attttctact aaaattatgt ttttgaataa cctctatctt
       61 agtagtttgt ataatccccc tcaatcagtt tttgcgataa gctttaatgc tatgactata
      121 ccactcttgc atttcttttg atggtggtgt catataatcg ccatacatct gggttaaaaa
      181 ttggtcatat tttttgggaa caggcaacat acggccctca aactcagtta aaatcagttc
      241 tttaaaggta tcaactggga agatttcttt catcccttcc ttaccgatcc caactcctcc
      301 ttcatattga ggaatgttgg ttacagcatt tttgactagt tgatcaattt tcttgtaaaa
      361 gtagcgagga ttgacaaatc ggagagcgta ccagctacat aatctaagaa aatcttttag
      421 tttgctatca ccgtgaactg ctcgtgattt tttgatataa gctagttgac gaagagccac
      481 atacttatag ctcttgtcga caatgctcaa gtctgtaaat cgatcaattg ggaagacatc
      541 gatgaaaagg ctggtatcat gacgcttgta cttaacatgg tcttctataa cagtagaagt
      601 gtccaaaatc gatgcgaaat tatggaagta ccaagaagat gtatcgtagg aaagaacctt
      661 gtagcgaggg tgattttctt cttcaataat cttcagtaaa cgctcataat cctcacgata
      721 aagggaaata tcaatatcat catcccaagg aatcatacct ttgtggcgga tggctccaag
      781 catggttcca taactgagaa aataaggaat atcatgtttc ttacaagtct catcaatata
      841 gtccagcagg gctagttgaa tttctttaat ttcttttttt tctaaatatt gcatcctaat
      901 cctccaattt ataagcgtga aattcatgac tgtagaagcg tttttcttct ggtggtaggg
      961 tcatataatc tccataaaat tgtgtcaaaa tagtatcaaa tttttcaggt gcaggaaggc
     1021 ttaaattctc aaagggtaaa tcgattgttt tatcaaaggt accacttggg aagacttcct
     1081 tttccttaaa ttttgaaggg ataaaagcca tatactgccc attttcacga ctatattttt
     1141 gaatttcttt ctcgatttta tttgcaaaat aacgaggaga aactggtcga aggagcaacc
     1201 aaaaggctgt tcgtatccaa tcttttaaaa ggctatcctt atagacaata tttttatgtt
     1261 tactgaaaga cagcagtttg aagctttcca gtttataaca agtatcaatg accttaggat
     1321 catcaaagcg atccataggg aaaatatcga taaagatacc agactcatag gtttttgtat
     1381 ttcgagtatc aataatttta gtcgtactgt cggttatctt gataaagttg ttaaagtagt
     1441 tcttatcagt ttctaaggat aggagttcat acttgctttt ttccttttga aaaatgttaa
     1501 taaatcgttg gtagtcttct ctaggcatgg ataaatcaat atcgtcgtcc caagggataa
     1561 agccctcatg tcgaaccgcc ccaatcagag taccgtagtt aataatatag ttgatattgt
     1621 gctttttaca gagagtatca atataatcca aaatttctaa ttcaatttgt ttggcatctt
     1681 caacggttag ttgtttcatt ttaaactcct atgatttttt aaatttattt tttaaggcta
     1741 gaacatggtt taaaaattca tagaaaatgc tatcttttgt gaagacaagt agactaatat
     1801 aagagatagc tgatagcaag ataatcaaac cagtattaat caaaaatggc aaattaatga
     1861 ccatatccac aggatacacg aaattaatca ggaaataaat tgctacaaag gaaagtgaaa
     1921 agagagagta tcgaacagta tagctaaaga tatgtcccaa gtggatgagt tgttttctat
     1981 ggatgaaaat gatatagaaa acaagtagag aagcctctga taacatagtt gtcagtaagt
     2041 agtattcggg agccacgata cggttgaaaa agaggagact attcaagccc aaattgagta
     2101 gcccagcaaa gactgtataa actgtgatac gtttttcata gccattggta aagagaattt
     2161 gggaaccaag aatggtatct aaggccagga taatcgtacg aaaagcgaag agagaggtca
     2221 agatgccgcc tccgatatat ttttcactac cgtaaagtag gatggcattt ggtcctaaaa
     2281 ccatgagtcc aaaactcagt ggaatgataa agaagttaaa gattcgacta cctctattaa
     2341 ccagagaaac ataggcttct ttgtctcctt tccccagata gtaactgaga cgaggcacac
     2401 tcactccaat tgcacctgtt acaaccccag ctataacggt cacaattcgc tgagctatgg
     2461 tatagtaact aacgttgaca tcaatccctg ttttaacgag gaagaggcga tctaaaaaag
     2521 tgaagagcat attggcattg gcaaagacta acatggctgt cagagggaga aagagtggtt
     2581 taaaatcact taggtgaatc ttaacaagtt tgatgtctct tttaatccaa aaataactaa
     2641 tcaggtagtt aatcagcgtc gataaactca tcacaagtgt atagacaaca atatcgtgtt
     2701 catttttaac aaataagaaa atagagacca gcatcaggat acggatgaag gcagttttgt
     2761 aaaagagaaa actgtaattt tccagagctt cattgaccca ttcgattgaa aaaatctggg
     2821 caatgagttg aatccccata acaaggtaga cctttttgat gattggatta tcagtaaaga
     2881 agagaggata ggctaggata tagacagcag tggtcaaaat cgtacaagcg atgcacaaat
     2941 aaaaaagact agaaaaggtt ctgttaagat cttttttgtt atccttgaca ttactgatag
     3001 cccttaaacc gtagttatag acaccataag ttgcaaaggg caagaaaaat gacaaaatag
     3061 tgtcgactga gttgaagtaa ccatagtcag ttcggtccaa gacacgcgcg acataggttc
     3121 cagttaggat gggaaaaata atattcaaga cacgaattcc catgtaagat agagcattta
     3181 attttatact tttcattcaa tttacctcgt ttttcattat atcataaagt tagctaataa
     3241 gaaatgaagg gcagtaagcc aagcaatcac tttgaagttt caaatcttaa attttaagtt
     3301 ttctttaagg aaagtatatt attctgaagg actctaaaat ttcgcagtca tttattagta
     3361 attgctacag aattcctagt cattactaga aatggactag tttctttgaa taatagaact
     3421 gcataattct cctattctag aaggggagga ccagtatttc ttttatgata ggactagatt
     3481 gtggtataat agagagaata agttttttta gtaagacaaa ggagaaaata gatgatttat
     3541 gcaggaattc ttgccggtgg aactggcaca cgcatgggga tcagtaactt gccaaaacaa
     3601 tttttagagc taggtgatcg acctattttg attcatacaa ttgaaaaatt tgtcttggag
     3661 ccaagtattg aaaaaattgt agttggtgtt catggagact gggtttctca tgcagaagat
     3721 cttgtagata aatatcttcc tctttataag gaacgtatca tcattacaaa gggtggtgct
     3781 gaccgcaata caagtattaa gaaaatcatt gaagccattg atgcttatcg tccgcttact
     3841 ccagaggata tcgttgttac ccacgattct gttcgtccat ttattacact tcgcatgatt
     3901 caggacaata tccaacttgc ccaaaatcat gacgcagtgg acacagtggt agaagcagtt
     3961 gatactatcg ttgaaagtac caatggtcaa tttattacag atattccaaa tcgtgctcac
     4021 ctttatcaag gacaaacacc tcaaacattc cgttgcaagg acttcatgga cctttatgga
     4081 tctctttctg atgaagagaa ggaaatcttg acagatgcat gtaaaatctt tgtgatcaaa
     4141 ggaaaagatg tggccttggc caaaggtgaa tactcaaatc tgaagattac aaccgtaaca
     4201 gatttgaaga ttgcaaaaag tatgattgag aaagactagt aaaatgatta atcaaattta
     4261 tcaactaact aagcctaagt ttatcaatgt caaatatcag gaagaggcta ttgaccaaga
     4321 gaatcatatc cttatccgtc ccaactacat ggctgtctgt catgcggatc agcgttacta
     4381 tcagggaaaa cgtgatccca agattttgaa taaaaagctt ccaatggcaa tgattcacga
     4441 gtcatgtgga accgtcattt ctgacccgac cggaacctac gaggttggtc aaaaagttgt
     4501 catgattccc aatcagtctc ctatgcagag tgatgaagaa ttctatgaaa actacatgac
     4561 agggacccat ttcttgtcta gtggatttga tggctttatg agagagtttg tttctctccc
     4621 taaagatcgt gtggtggctt atgatgctat tgaagatacg gttgcagcca ttacagagtt
     4681 tgtcagtgtg ggcatgcacg ctatgaatcg tctattgact cttgctcata gcaagcggga
     4741 gcggatcgcc gttattggag atggaagttt agcttttgtg gttgccaata ttatcaacta
     4801 tactttgcca gaatcagaga ttgtggttat tggtcgtcat tgggaaaagt tggaactctt
     4861 ctcatttgcc aaagaatgct atattacgga taatattcct gaagagttgg cctttgacca
     4921 tgcttttgaa tgttgtggtg gtgatggtac tggaccagct attaatgact tgattcgcta
     4981 cattcgtcct cagggaacga ttctcatgat gggagttagc gaatataaag tcaatctcaa
     5041 tactcgcgat gccttagaaa agggcttgat tttggttggg tcatctcgtt ctggtcgcat
     5101 tgattttaaa aatgctatcc aaatgatgga agtcaagaaa tttgccaatc gtcttaaaaa
     5161 tatcctttat ctagaagaac ctgtaagaga aattaaagat attcatcgtg tctttgcaac
     5221 cgatttaaac acagccttta aaacagtgtt taagtgggaa gtataagtac tggaggttaa
     5281 ttgtggagaa aatcattaaa gaaaaaattt cttccttact tagtcaagaa gaggaagtcc
     5341 tcagtgttga acaactgggt ggaatgacca atcaaaacta tttggccaaa acaacaaata
     5401 agcaatacat tgttaaattc tttggtaaag ggacagaaaa gcttatcaat cgacaagatg
     5461 aaaagtacaa tcttgaacta ctaaaggatt taggcttaga tgtaaaaaat tatctttttg
     5521 atattgaagc tggtatcaaa gtaaatgagt atatcgaatc tgcgattacg cttgattcaa
     5581 cgtcaatcaa gaccaagttc gacaaaattg ctccaatatt acaaactatt catacgtctg
     5641 ctaaggaatt aagaggagaa tttgctcctt ttgaagaaat caaaaaatac gaatccttga
     5701 ttgaagaaca aattccttat gccaactatg aatctgttag aaatgcagtc ttctccttag
     5761 agaaaagact ggctgactta ggtgttgaca gaaaatcttg tcatatcgat ttggtgcctg
     5821 aaaactttat cgaatcacct caaggacgac tttatttgat tgactgggaa tattcatcaa
     5881 tgaatgatcc aatgtgggat ttggctgccc tctttttaga gtctgaattc acttcccaag
     5941 aggaagaaac tttcttatct cactatgaga gtgaccaaac accggtttct catgaaaaga
     6001 ttgctattta taaaatttta caagatacta tttggagtct atggactgtc tataaggaag
     6061 agcaaggtga agattttggt gactatggtg tgaatcgtta ccaaagagct gttaaaggtt
     6121 tggcttctta tggaggttca gatgaaaagt aaaaacggag ttccttttgg ccttctctca
     6181 ggtattttct ggggcttggg tctaacggtt agtgcttata tcttttcgat ttttacagat
     6241 ttgtcaccct ttgtggtggc tgcagctcat gattttttga gcatctttat cttactagct
     6301 tttctcttgg taaaagaagg gaaagttcgc ctctcaattt tcttaaatat tcgcaatgtc
     6361 agtgttatca tcggagcctt gctagcaggc cctatcggta tgcaggccaa tctttatgca
     6421 gttaagtata tcggaagttc tttagcttca tctgtatcgg ctatttaccc tgcgatttca
     6481 gttctattgg ctttcttctt tttgaagcac aagatttcga aaaatactgt atttgggatt
     6541 gtcttgatta ttggagggat tattgctcag acctataagg ttgaacaggt taattctttc
     6601 tacattggga ttctttgtgc tttggtttgt gctattgcat ggggaagtga gagtgttctt
     6661 agctcttttg ccatggaaag tgaattgagt gaaatcgaag ccctcttaat ccgtcaagta
     6721 acttcgttct tgtcctatct tgtgattgtg ctcttctctc atcagtcatt tactgcagta
     6781 gccaatggac aattgctagg tctcatgatt gtttttgcag cctttgatat gatttcctac
     6841 ttggcttatt atatcgctat caatcgcttg caaccagcca aggctacagg cttgaacgtg
     6901 agctatgtag tatggacggt cttgtttgca gttgttttct tgggtgcacc gctagatatg
     6961 ctgaccatta tgacgtcact tgtcgtcatt gctggagttt atattattat taaagaataa
     7021 aggagattcg tgtgaaagcc attatcttag cagcgggatt gggaactcgc ttgcgtccta
     7081 tgactgaaaa tacccctaaa gccttggttc aggttaatca aaaacctttg attgagtacc
     7141 aaattgagtt tctcaaagaa aaaggaatca atgacatcat catcattgtt ggttatctta
     7201 aagaacaatt cgattacttg aaagagaaat acggtgttcg tctcgttttc aatgataaat
     7261 acgctgacta caataacttt tactctctct atcttgtaaa agaagaattg gccaacagct
     7321 atgttattga tgctgacaat tatctcttta aaaatatgtt ccgcaatgat ttgacacgtt
     7381 cgacttattt tagtgtttat cgtgaagatt gtaccaacga atggttcttg gtttatggag
     7441 atgactacaa ggttcaagac attattgttg atagcaaggc aggtcgcatc cttagtggtg
     7501 tatccttctg ggatgctcca actgcagaaa agattgtcag ctttatcgac aaggcttatg
     7561 taagtggtga atttgttgat ctctattggg acaatatggt taaggataat atcaaagagc
     7621 tagatgtcta tgttgaagaa ttagaaggca atagcattta tgagatcgat agtgtccaag
     7681 actatcgtaa attagaagaa attcttaaaa acgaaaatta aagattccaa catctgacaa
     7741 aatagtcgga tgttttttga ttttttacga acttttacga atagatagat gagtagaaaa
     7801 agaaatggag ttatttatga aaatcacaaa ctatgaaatc tataagttaa aaaaatcagg
     7861 tttgaccaat caacagattt tgaaagtgct agaatacggt gaaaatgttg atcaggagct
     7921 tttgttgggt gatattgcag atatctcagg ttgccgtaat ccagccgttt ttatggaacg
     7981 ttattttcag atagacgatg cgcatttgtc gaaagagttt caaaaatttc catctttctc
     8041 tattttagat gactgttatc cttgggattt gagtgaaata tatgatgcgc ctgtactttt
     8101 attttacaag ggaaatcttg acctcctgaa attcccgaag gtagcggtcg tgggcagtcg
     8161 tgcttgtagc aaacagggag ctaagtcagt tgaaaaagtc attcaaggct tggaaaatga
     8221 actggttatt gtcagtggtc tggccaaggg cattgacaca gcagctcata tggcagctct
     8281 tcagaatggc ggaaaaacca ttgcagtgat tggaacagga ctggatgtgt tttatcctaa
     8341 agccaataaa cgcttgcaag actacatcgg caatgaccat ctggttctaa gtgaatatgg
     8401 acctggtgaa caacctctga aatttcattt tcctgcccgt aatcgcatca ttgctggact
     8461 ttgtcgtggt gtgattgtag cagaggctaa gatgcgttca ggtagtctca ttacgtgtga
     8521 gcgagcaatg gaagaaggac gcgatgtctt tgctattcct ggtagcattt tagatggact
     8581 atcagacggt tgccatcatt tgattcaaga aggagcaaaa ttagtcacca gtgggcaaga
     8641 tgttcttgcg gaatttgaat tttaaaaatg acctaagcta gaattctaag aaaaaatcaa
     8701 ttttaagaga aaatgaaccc aacatttcca taataaaacg catattagca agtttttaac
     8761 acttgataat atgcgttttt tctaagtgga ttagtagagt agaggatttt tctcatataa
     8821 tactcttcga aaatctcttc aaactacgtc agcttccatc tgcaacctca aaacagtatt
     8881 ttgagctgac ttcgtcagtc ttatctacaa cctcaaagca gtgctttgag caacctgtgg
     8941 ctagcttcct agtttgcgct ttgattttca ttgagtataa gggaaagtat agtgaattga
     9001 aataagatgt gaacaactct atcaggaaag tcaaattgat ttatagaaat attttagcag
     9061 ccaaggtgca ctgttataga ttcaatacac tataatttag tgtaattgag aaaggagaaa
     9121 tgattgtgat tgatgttggc taggttatgt tcaatgattc ctaccgtctc aaatcttgtc
     9181 agtaaggaaa aataaattct tcaaaagtag agattacaag gcttgtttaa gaaagaattc
     9241 aaagaccttg acaaataaaa ataaaatggt tattataaaa aatggtctga aatagatgat
     9301 gatacttttc gaaaatctct tcaaactacg tcagctcagc tttgccttgc tgtgttttga
     9361 gcaagctacg gttagcttcc gagtttgatt ttcatttact agaaatgaaa ctgatgagag
     9421 atatcagtag acatttgagt caggatatta tggaaaatga taaaaagagc tcgtgagatt
     9481 ggcatatcag actactaaag tattgagttt gttaggattt tagcgactag ttagctggga
     9541 aaggaagata tttgtgacaa ataataaact gtattcgttg atagaattta gaaataaaat
     9601 atatgaagaa ttagaacttt ccagaagtga tttagcgatt ttactatgtg ccatgcttat
     9661 cgcctctatc ggattaaata tggattcgac tcccgtgatt attggagcca tgttaatctc
     9721 tcctttgatg acacctattc tgggagtggg gctctctcta gctatatttg attttaaatt
     9781 gttaagaaaa tcttttaaaa tattagctat tcaaattctt gccagtctaa tagcttcaac
     9841 actttatttt tatctttctc ccatttcgta tgctagttcg gagattgttg ctagaacctc
     9901 tccgactatt tgggatgttc tcattgcttt tgtaggaggg atagcaggta ttattggtgc
     9961 taggaaaaaa gagaccaata atattgttcc tggtgttgct attgcaaccg ccttgatgcc
    10021 tcctctttgt acagtaggtt atgctattgc ttctgctaat ctaaaattta tcataggctc
    10081 ctcttaccta ttcctcatca attgtagctt tattgtcatt gcgacttata taggtgttag
    10141 gttgatgatg gttaagaaac attattttaa agataatgaa gaagactcta aaatgcgtag
    10201 gattttgctt ctagttgctg ttttgctgat gattccgagt ttcatctctg caacgacttt
    10261 agtgagagaa acgttgaaaa aagagtccct taagaaattt atatcagagc agtttcaggg
    10321 gtataatatt ttgaaaaaaa cctattctaa aaagactcat accctaaagc taaccatttc
    10381 aggaaattat ttgacagaag aagaactcga tatgatttca agtaagagag gtgactatgg
    10441 tttaagtgat gtttctgttc aagtttcaca attgtctgat tcagaacaac ttagtaagga
    10501 agagctggtg gagtatttct tccagtatat caaggataag gaagcaaaag aaaaggagaa
    10561 agccaataaa tttgatacag agtctgagga gcaataattt cttgagaata gctggtttct
    10621 ctcgtgagtc ttctatgtat atcaaaggaa gactgaggtt ttaagtataa aacttttctt
    10681 ctattatagt agctaagtct tgacagggtt caaaaaatgg tttacacttt ataaagttta
    10741 ttactttgaa aaggtgtgat actgtggcta cggcaacaaa aaagaaaaaa tcaacagtta
    10801 aaaaaaatct agtcatcgtg gagtcgcctg ctaaggccaa gacgattgaa aaatatctag
    10861 gcagaaacta caaggtttta gccagtgtcg ggcatatccg tgatttgaag aaatccagta
    10921 tgtccgtcga tattgaaaat aattatgaac cgcaatatat taatatccga ggaaaaggcc
    10981 ctcttatcaa tgacttgaaa aaagaagcta aaaaagctaa taaagttttt ctcgcgagtg
    11041 acccggaccg tgaaggagaa gcgatttctt ggcatttggc ccatattctc aacttggatg
    11101 aaaatgatgc caaccgtgtg gtcttcaatg aaatcaccaa ggatgcagtc aaaaatgctt
    11161 ttaaagaacc tcgtaagatc gatatggact tggtcgatgc ccaacaagct cgtcggatct
    11221 tggatcgctt ggtagggtat tcgatttcgc ctattttgtg gaagaaggtc aagaagggct
    11281 tgtcagcagg tcgcgttcag tccattgccc ttaaactcat cattgaccgt gaaaatgaaa
    11341 tcaatgcctt ccagccagaa gaatactgga cagttgatgc tgtctttaaa aagggaacca
    11401 aacaatttca tgcttccttc tatggagtag atggtaaaaa gatgaaactg accagcaata
    11461 acgaagtcaa ggaagtcttg tctcgtctga cgagtaaaga cttttcagta gatcaggtgg
    11521 ataagaaaga gcgcaagcgc aatgctcctt taccctatac cacttcatct atgcagatgg
    11581 atgctgccaa taaaatcaat ttccgtactc gaaaaaccat gatggttgcc caacagctct
    11641 atgaaggaat taatatcggt tctggtgttc aaggtttgat tacctatatg cgtaccgatt
    11701 cgactcgtat cagtcctgta gcgcaaaatg aggcggcaag cttcattacg gatcgttttg
    11761 gtagcaagta ttctaagcac ggtagcaagg tcaaaaacgc atcaggtgct caggatgccc
    11821 atgaggctat tcgtccgtca agtgtcttta atacaccaga aagcatcgct aagtatctgg
    11881 acaaggatca gcttaagcta tataccctta tctggaatcg ttttgtggct agccagatga
    11941 cagcggccgt ttttgatacc atggctgtta aattgtctca aaaaggggtt caatttgctg
    12001 ccaatggtag tcaggttaag tttgatggtt atcttgccat ttataatgat tctgacaaga
    12061 ataagatgtt accggacatg gttgttggag atgtggtcaa acaggtcaat agcaaaccag
    12121 agcaacattt cacccaaccg cctgcccgtt attctgaagc aacactgatt aaaaccttag
    12181 aggaaaatgg ggttggacgt ccatcaacct atgcgccaac cattgaaacc attcagaaac
    12241 gttattatgt tcgcctggca gccaaacgtt ttgaaccgac agagttggga gaaattgtca
    12301 ataagctcat cgttgaatat ttcccagata tcgtaaacgt gaccttcaca gctgaaatgg
    12361 aaggtaaact ggatgatgtc gaagttggaa aagagcagtg gcgacgggtc attgatgcct
    12421 tttacaaacc attctctaaa gaagttgcca aggctgaaga agaaatggaa aaaatccaga
    12481 ttaaggatga accagctgga tttgactgtg aagtgtgtgg cagtccaatg gtcattaaac
    12541 ttggtcgttt tggtaaattc tacgcttgta gcaatttccc agattgccgt catacccaag
    12601 caatcgtgaa agagattggt gttgagtgtc caagctgtca tcagggacaa attattgagc
    12661 gaaaaaccaa gcgtaatcgc ctcttctatg gttgcaatcg ctatccagaa tgtgaattta
    12721 cctcttggga caagcctgtt ggtcgtgact gtccaaaatg tggcaacttc ctcatggaga
    12781 aaaaagtccg tggtggtggc aagcaggttg tttgtagcaa aggcgactac gaggaagaaa
    12841 agattaaata agaggagggg cccgaaagta aatttcaggc tccttttggt tagaacttga
    12901 caaaatacat cattttatgc gaaactagaa gaagattatt ttaactagga gaagttatgc
    12961 gtcttatcta tctgataatt ggttttttat cactggcctt ggctattgtt ggggttgttt
    13021 tacccttgtt gcctacaaca cctttccttt tgttgtctat tgcttgtttc tccagaagtt
    13081 ccaagcgatt cgaagactgg ctttatcata ccaagctcta tcaaacatat gtagctgatt
    13141 ttcgcgagac taagtctatt acgcgtgaac gaaagaaaaa aatcatcgta tccatttaca
    13201 ttttgatggg gatttctatt tattttgccc ctctcttacc agtcaaaatc ggtctgggtg
    13261 ctttgaccat ctttatcact tattatctct tcaaggtcat tccagacaaa gaatagttaa
    13321 aacagtagtt atttaccttg ataaaattga aagcatattc ataacaatat gatataataa
    13381 atttgaagta atattcaagg agaatcaaat gatttacgaa ttttgtgctg aaaatgtgac
    13441 tttacttgaa aaagcgatgc aggctggagc tcgtcggatt gaactctgtg ataatctagc
    13501 agttggtggg acaacaccta gctatggagt gactaaggca gcggttgaac tggcagctaa
    13561 ctacgataca accatcatga ccatgattcg gccacgtggt ggtgactttg tctataatga
    13621 cctagaaatt gctatcatgc tagaagacat ttgtttgact gctcaggctg gaagtcaagg
    13681 ggttgtattt ggagctttaa ctgctgataa aaagttggat aagcctaatc tggaaaagtt
    13741 aattgctgca tcaaaaggaa tggaaattgt ctttcacatg gcctttgatg aactaagtga
    13801 tgaagatcaa ccggaagcta ttgactggct cagtcaagcc ggtgtcactc gtatcctaac
    13861 tcgtgctggt gtgtctggcg actccttaga aaaacgtttt gttcactatc acagaatttt
    13921 ggagtacgct aaaggtaaaa ttgaaattct accaggtggg gggattgacc ttgacaaccg
    13981 tcaaaccttt attgaccagg tgggggtaac acaattgcat ggtactaagg ttgtttttta
    14041 aaaaatagaa aggaactgct agccttgggt agcagttttc acttatgttt gaaattttta
    14101 aatcctatca atttaatcaa gaaaaggctc atgattatgg ttttatagaa aatagcgaag
    14161 tctggacata tagttgccag attttgcaag gtgactttgt catgactgtg tccatcactg
    14221 ctgataatgt gaactttcaa gtctttgacc aagagactgg tgacctctat cctcacgttc
    14281 atatggaaag catgagggga agttttgtcg gaaatgtccg tgaggcttgt ctggagattc
    14341 tttaccagat tcggaaggct tgttttgatg tgcaagattt tatctgtcat cagactaagc
    14401 gtatcatgac tcaagttcag gaaaagtatg gaaaccagtt ggagtatctg tgggaaaaat
    14461 cgcctgatac agctgtattg cgccatgaag gcaatcaaaa gtggtatgcc gtcttgatga
    14521 aaatctcttg gaataagctg gaaaagggca gagaaggaca agtggaagca gtcaacctca
    14581 agcatgacca agtagctaat ttgctttcac aaaaggggat ttatccagcc ttccatatga
    14641 gcaagcgcta ctggattagt gtgtcccttg atgatacttt atcagatgaa gaagtactgg
    14701 aattgataga aaaaagttgg aacttaacct ctaaaaaatg aaatatttta ataattttca
    14761 tgaactttca attagctaaa tattctttac tgaagaaatt tttagaaaat ataggattta
    14821 ccacactaga ggaatatggt gccatcttca aatacctgat tgagaatgtc aagacggatc
    14881 gtcagatcat ctgttcgcct cactgtcatg atgacctcgg aatggcagtg gcaaatagcc
    14941 ttgctgctgt caagaatggt gcaggacgtg ttgaagggac tatcaatggt attagggagc
    15001 gagctgaaaa tgctgctttg gaagaaattg cagtggctct caatattcgc caagattact
    15061 accaagtaga aaccagtatt gtcctaaatg agaccatcaa tacgtcagaa atggtttctc
    15121 gcttctctgg tattccagtt cctaaaaaca aagccgtcgt tggtggcaat accttctccc
    15181 acgaatctgg tattcaccaa gatggagtcc ttaaaaatcc tctcacttat gagatcatca
    15241 cacctgaatt ggttggtgtt aagattccgc ttggaaaatt atctggtcgc catgcttttg
    15301 ttgagaaact gagagaattg gccctagatt ttacagaaga ggatatcaaa ccactctttg
    15361 ctaagttcaa ggcactggcc gataagaagt aagaaatcac agatgcagat cctcgagctt
    15421 tggtagctgg aaccatggtt gaaaatccag aaggcttcca ctttgatgat ttacaacttc
    15481 aaactcatgc agataatgac attgaagcgc tcgttagcct agccaatatg gatggtgaga
    15541 aagtcgaatt taatgcgaca gggcaaggtt ccgttgaagc aatctttaac gctatcgata
    15601 agttctttaa ccaatctgtt cgtttggtgt cctacactat caatgcggta acagatggaa
    15661 tcgatgccca ggatcgggtt ttggtcactg ttgaaaacag agatacagaa accatcttta
    15721 atgcagcagg gcttgatttt gatgtgttga aggcttctgc tattgcctat ataaacgcta
    15781 atacctttgt tcaaaaagag aatgcaggtg agatgggacg cagtgtttct taccacgata
    15841 tgcctagtgt gtaaaggaga aggctatggc aaagaaaata gtagctctag taggagacgg
    15901 aattggccca gaaatcatgg aggctggttt agaagttctg gaggctctag ctgaaaaaac
    15961 aggttttgac tatgagattg acagacgacc gttcggaggt gcagatattg atgcagcagg
    16021 acctccctta cctgatgaaa cccttaaggc aagtagggaa gcagatgcta tcctactagc
    16081 agctatcggt agtcctcagt atgatggagc agcggttcgc cctgaacaag gcctgatggc
    16141 tctccgtaag gaactcaatc tttacgctaa tattcgtcct gtaaaaatct ttgacagtct
    16201 caagtatttg tcaccactca aaccggaacg aatttctggt gtagactttg tcgtggtgcg
    16261 tgaattgaca ggcgagattt actttggaga tcatattctt gaagagcgca aagcgcgtga
    16321 tatcaacgac tatagctatg aggaagtgga gcggattatt cgcaaagcct ttgaaattgc
    16381 aagaaatcgc agaaaaatcg ttactagtat cgataagcaa aatgttctag cgacctcaaa
    16441 actctggcgg aaagtagctg aggaagtcgc acaggatttc ccagatgtaa ccttggaaca
    16501 ccagctggta gactcagctg ctatgcttat gattaccaat cctgctaagt ttgatgttat
    16561 tgtaacggag aatctttttg gagatatttt atctgatgaa tcaagcgtct tatctggtac
    16621 acttgaggtt atgccatcag ccagtcattc tgaaaatgga ccaagtctct atgaacctat
    16681 tcacggttca gcacctgata ttgcaggtca aggaattgcc aatcctactt ccatgatttt
    16741 atcagttgcc atgatgttga gagatagttt cggacgttat gaggatgcag agcgtatcaa
    16801 acatgctgtt gagacaagtc tggcggcagg aattttaacg agagatatag gaggtcaggc
    16861 ttcaacaaag gaaatgacgg aagctattat tgcaaggtta tgaagttaga cgaaaaaatt
    16921 actctagtcc ttttgatttg gaatgtcatc attttcttga tttatggcat tgacaaattc
    16981 aaggcaagaa gaagaacttg gcgcatccaa gagaaaatct tactcatttt agcccttact
    17041 tgtggtggtt ttggggcctg gttagctgga atcacttttc accacaagac tcgaaaatgg
    17101 tactttaaaa cagtttggtt tcttgggatg gtgaccacac tagtagcctt atattttatt
    17161 tggaggtaat ggatggcagg gtcttcgagg gaacacgctg cttgggttct agcggactat
    17221 ggttttaagg tcgtgattgc aggatctttc ggtgacattc attacaataa tgaactcaat
    17281 aatggcctgt tgccaatcgt tcagcctaga gaggttagag agaaactagc ccagctaaaa
    17341 ccaaccgacc aggtaactgt ggacttggaa caacaaaaaa tcatctcacc agttgaagaa
    17401 ttcaccttcg agatagatag cgagtggaaa cataaactcc taaatagttt ggatgatatc
    17461 ggtattacct tgcagtatga agagttgatt gctgcttatg aaaaacaacg accagcctac
    17521 tggcaggatt agaaaaaata gaaaaggaaa tatagtaaac tgaaataaga tgtaaacaaa
    17581 tgaattagag cttaacatcc atttccagca attttttaga aactacagtg gactattctg
    17641 gattcaacac attataaaat tatgacaaaa cacattcaca agaaggctac gacattttaa
    17701 aaggtgaggg cggatgtatc gtttgcccta ctaaagttgg ttacattatc atgaccagca
    17761 acaaggcagg acttgagcgt aagttcgcag ccaaagaacg taagcgtaac aaaccaggtg
    17821 ttgttctctg cggtagcatg gatgaacttc gcgctttagc gcaactcaac ccagaaattg
    17881 aagcattcta ctaaaaacat tggatgaaga tattcttctt ggttgtatcc ttccttggaa
    17941 accagaagcc tttgaaaaac tcaaagcata cgggaatggc cgtgaagaac ttatgactga
    18001 tgtacgtggt actagctgtt ttgttatcaa gtttggaaaa gcaggtgaac aattggctgc
    18061 caagctttgg gaagaaggta aaatggtcta cgcctcatat gcttcaatga caaaacgatt
    18121 gaaactcgct atgagagcaa ggtgtaatgg tgtctatggt cgataaggac ggcaaactca
    18181 tcccagaaca aggaggagca cgttcaactt caccagcacc agttgtgatc cgtaaagggc
    18241 ttgacattga taaaatcatg atgcacctgt cagatacttt taactcatgg gactaccgtc
    18301 aggttgagta ttattaagat aaaaaaagaa gtctagtgtt atgagatatt aaagctccta
    18361 acactggact ttttgtttag aatttctttt ctttttctat aggatatggt attctatgta
    18421 gaaaatatat gttaataagt aatgccaata tttaaacatc attagtaaaa ggagttagat
    18481 tgatgaataa aagaaaagtt agtttagaag atttttataa atggtatagt ctaaataaag
    18541 aagagttatt aaataaggca actgttggtg aaaagtttaa tgataaatta aaagaagagt
    18601 ttctccagga atggcctttg gataggattt taacaatgtc aatcgatgaa tatgtaatag
    18661 gaaagggaca gcaaaataag tctttatgct acgctcttga gaagggaaaa tacaaaaatc
    18721 tatttcttgg aatttctggt ggctcagctt caaaatt
//
LOCUS       DAVLBE010000034        18583 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.034, whole genome shotgun sequence.
ACCESSION   DAVLBE010000034 DAVLBE010000000
VERSION     DAVLBE010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18583)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18583)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18583
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.034"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            68..310
                     /locus_tag="VXB91_001333"
     CDS             68..310
                     /locus_tag="VXB91_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0470780.1"
                     /translation="MKINEYLWRTSCLILLIIMSFFAGFGAKLEFTSYNPFLSVKFGL
                     VVALTVFVVQLLAILPAMVKRGNKNENVESNNSCEE"
     gene            273..1664
                     /locus_tag="VXB91_001334"
     CDS             273..1664
                     /locus_tag="VXB91_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001242574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HEV0470781.1"
                     /translation="MRMLNQTIRVKSKYPYLIRPRNIKIVRLFIQIFVFLLLISSWIA
                     IIPFIARLVFSMFFISLLFFVEKFFRSNFIAKLRNKLNIREALFYMLISLNLYDELDN
                     EVVDTAVLYFDVENNKVVVCAPLFGNRYLKTLKNLEEYLCPTLGLSLLSKKEEIDKIV
                     YVLGQKEEIEQYVFNSNTLTREFFKDIPSSIIKLSNTQKFSLKSNTNLGIYGRTGTGK
                     TIALQWYLFNALAKGCGIADNTYLGIVDGKAADLYRIGELLHEELGEQVAVGSSPQML
                     AQLSRKFIENMDARFKIIKQNSSLNADIYELDELGLVPNFLFVDELASIRDSCGSTKQ
                     GRETWNEILQNLGLIARKGRQAGCHLVLSTQDPNAENIPVELRNQISAVLYLGAPGAD
                     RLKMAFSMCELENVPTVSDRKGEALFYADGLNTVEPVLTIVPFVDLKTKKEFLNVVRN
                     ILPTNDGLPPLAK"
     gene            1920..2339
                     /locus_tag="VXB91_001335"
     CDS             1920..2339
                     /locus_tag="VXB91_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002922924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0470782.1"
                     /translation="MVYNMTDTNIKIGLLDLEMSQFDIPKKVVILSVRVNNKYKEVNG
                     ENVKTDEVSKITSAVLDADKVKVLTEMGISTDDLKAINLEIIGNLDKIAKLAQNDALL
                     NVPVELIRPKVRLAWNMARNNWSGVKIVCEDIKVLGE"
     gene            2344..3363
                     /locus_tag="VXB91_001336"
     CDS             2344..3363
                     /locus_tag="VXB91_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HEV0470783.1"
                     /translation="MNTVRIDYFAVTVKNISPEKVLTDILLIPLENFTLNDWGINKYK
                     QHYSCSEIKVYFNADRLSMGVFIELKGQGCRQYEEFLNSNENNWIALISRLYHHNANF
                     TRLDIAHDIFDGSLDVQRIYDYCKKGLCISKAKHFEYHEKSVLDSGERVGETVAIGSR
                     GNQQWCIYNKRMEQLGKQELVEVSSWTRAELRCWQEKANIIAEQLYLKRPLSSIYFEA
                     INGHYRFIRPNAIDSNRWRRKKVEWWVNYLGTENQTVLSITRAKTTLRESEVWTEKQV
                     AKTLAKVYIAKYQAYDVQKAEDYIQNLLKEGLSKLTDNDEKDIEQYIREQNSSQLWGT
                     DGRSD"
     gene            3367..3549
                     /locus_tag="VXB91_001337"
     CDS             3367..3549
                     /locus_tag="VXB91_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000184042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HEV0470784.1"
                     /translation="MADTISNKDLISMGYRPSTANAIIHQARELLVSRGYTFYNRKRL
                     MVVPKSVVKELLGMEL"
     gene            3551..4678
                     /locus_tag="VXB91_001338"
     CDS             3551..4678
                     /locus_tag="VXB91_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000323402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEV0470785.1"
                     /translation="MAYIEYKQRGKKRLWSFSIRERSKSLLHKSGFKTKREAKIEAEK
                     VLHKLNTGSVLSSSMTLSELYNEWLDLKILPSNRSVVTKKKYLMRKKVIERLFGNKPV
                     SQIKPSEYQKIMNEYGETVSRNFLGRLNSCIRASIQMAIADKVIIEDFTAYVELFSSK
                     SGQKVEEKYLHAESDYQKVLVYLKNKFDYQKSIVPYVIYFLFKTGMRFSELIALTWDE
                     VDELNEQLKTYRRYNTAIHKFTPPKNNTSIRLVPITSDMLSLLKTLKILQLKTNKELN
                     IDNENNLIFQHFGYVYDVPDIATVNKAIKVMLKELQIFPLITTKGARHTYGSYLWHNN
                     IDLGVIAKILGHKDISMLIDVYGHTLEEKISEEFMAVKSLL"
     gene            complement(4761..4833)
                     /locus_tag="VXB91_001339"
     tRNA            complement(4761..4833)
                     /locus_tag="VXB91_001339"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(4798..4800),aa:Lys,seq:ctt)
     gene            complement(5098..6369)
                     /locus_tag="VXB91_001340"
     CDS             complement(5098..6369)
                     /locus_tag="VXB91_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HEV0470786.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYTARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQKIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWVKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDRLRKI"
     gene            6639..6839
                     /locus_tag="VXB91_001341"
     CDS             6639..6839
                     /locus_tag="VXB91_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0470787.1"
                     /translation="MKREVISNGNDGPSQEILIFTKQIRHWILSDQVISGKRKLFFRE
                     DTPKEILDLYENIKSKLDFAYQ"
     gene            7043..7222
                     /locus_tag="VXB91_001342"
     CDS             7043..7222
                     /locus_tag="VXB91_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0470788.1"
                     /translation="MNLIFEEYQFVKIGDKKYRVRSVPMIHSTPPQSVLDRDTFTIDY
                     TDDELLDKEAVFTTH"
     gene            7359..7538
                     /locus_tag="VXB91_001343"
     CDS             7359..7538
                     /locus_tag="VXB91_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HEV0470789.1"
                     /translation="MPMTQKEMVKLLTAHGWIKTRGGKGSHIKMEKQGERLITIPHGE
                     LNKYTERGIRKQAGL"
     gene            7575..8027
                     /locus_tag="VXB91_001344"
     CDS             7575..8027
                     /locus_tag="VXB91_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HEV0470790.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            8318..8788
                     /locus_tag="VXB91_001345"
     CDS             8318..8788
                     /locus_tag="VXB91_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HEV0470791.1"
                     /translation="MATYGFLDVLEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVLSDDILFEEAVLFYNPAKSTVNEEDYLTVIPYLPKKGFSREFLAYF
                     ALFLKDTAEVGLDVLMDFLEDPEAEEFVMEWNQEVFEEGKVGLEEGEFYPYPRY"
     gene            8807..9895
                     /locus_tag="VXB91_001346"
     CDS             8807..9895
                     /locus_tag="VXB91_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000719715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HEV0470792.1"
                     /translation="MKKIGTYLVYVLAFVFIMLAFACGTIAFAELGYSAVLAFTFGYA
                     FALLSMYLIFILHELGHAFCGYLTGYRLVAFGLGHFILTKKSGRFHLSRTAILKNVGA
                     QYIGLKEDESDQRIILMLSGGLMVHLGLILLAIVFGFLTRSWYFAGTWIFLNLSFFLN
                     NILPVDITDGAKIWELLQHPENTKYAYLVLRHSAQTLLAPQEYDLKDFVQAVPEDARG
                     SFADGVLGMQGEVSILEGKEEVAKQQFQALLERTTTPMMQTVAQLSLLHIALLEGDFE
                     QAEQYASIRQVKSFLSLKLSNLQVIQAWYQFKVKKDVDRTRKALKIARQKMDSSRMLR
                     DEKRYYENLLAELEKEMLEGTEDGTRNF"
     gene            9876..10304
                     /locus_tag="VXB91_001347"
     CDS             9876..10304
                     /locus_tag="VXB91_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV0470793.1"
                     /translation="MELEISDFPGCKIALFCGDKLLTILRDDKASIPWANMWELPGGG
                     REGDESPFECVAREVYEELGIHLTEDCLLWSKVYPSMLFADKQSVFLVGQLTQNQFDS
                     IVFGDEGQGYQLMNVEEFLSSSQVVPQLQERLKDYLKVSD"
     gene            10442..11392
                     /locus_tag="VXB91_001348"
     CDS             10442..11392
                     /locus_tag="VXB91_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000451122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HEV0470794.1"
                     /translation="METWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYVGNVD
                     RFGEIFPEVEQQEEIVVTAYYPDTVDVTVVEADLQARISELTDFMDLGELKIGTTALA
                     EEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKMS
                     LFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNPG
                     MENIHVAAGDLLKGVEIEADVIVANILADILIHLIDDAYRLVKDEGYLIMSGIIKDKW
                     DMVRQSAESAGFFLETHMVQGEWNTCVFKKTKDISGVIGG"
     gene            11394..12137
                     /locus_tag="VXB91_001349"
     CDS             11394..12137
                     /locus_tag="VXB91_001349"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HEV0470795.1"
                     /translation="MQQYFVKGSAISPVTIEDKETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFIAQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNIVPSIKLFEKKADFLAQLDQ
                     FDFIIVAYEESAKEGEAAALLQAVTGLETGAKLLFIFGPEGGLSPAEIESFEAKGAVL
                     VGLGPRILRAETAPLYALSALSVLVELEK"
     gene            12148..13944
                     /gene="pepF"
                     /locus_tag="VXB91_001350"
     CDS             12148..13944
                     /gene="pepF"
                     /locus_tag="VXB91_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEV0470796.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYAFMPQTTDYSNDEFANIAQAGMEFETD
                     ASVALTFFDDALVVADEEVLDRLGELPHLTAAIRQAKIKKAHYLGADVEKALTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKNSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIIAYSAELGE"
     gene            complement(14004..14681)
                     /locus_tag="VXB91_001351"
     CDS             complement(14004..14681)
                     /locus_tag="VXB91_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000433071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0470797.1"
                     /translation="MEPDIFIITKLLSDPSRMHILDILMDGKAHTVNEIASFTKIKQH
                     TVSYHLKLLTEAQVTTLQTYGRFHYYSLKSAAIAEMLEFLSFYSPQRDVKSYKQHIHK
                     KELKVARTCYDHIAGELGISITNYLLQENLLSESEKDFQLTEAGKSYFQKKLHIDTDE
                     LKKKKRKFCPKCLDWSERKNHVGGALGNALLEFFSEKQLVIPAQTPRSLTITEQGKEF
                     LEKEWGI"
     gene            14928..15698
                     /locus_tag="VXB91_001352"
     CDS             14928..15698
                     /locus_tag="VXB91_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000966490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0470798.1"
                     /translation="MLYLLGKERVKKLSVKNLKKQYGSYEAVKGISFELGEGECLGIL
                     GINGAGKTSTLKMIYSLTSISSGEIDILGQNIETNRRKSKSCLGIVGQEDMLDMTLNV
                     YDNLFAHGLCYGISSVELRKRIDFLLDFVQLSKHAQKMVNQLSGGMRRRLVLARALIN
                     RPDIIILDEPTVGLDIQSRNIIWDKLLELKELGVSIIITSHYMNEIEYLTDRVLMLHQ
                     GTIKEEGTVEDLLIKYDADNLETLFLGLTGTEKEDLHV"
     gene            15691..16455
                     /locus_tag="VXB91_001353"
     CDS             15691..16455
                     /locus_tag="VXB91_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0470799.1"
                     /translation="MFKLSFHSIGHVVVRNYMSFRNLFKISIVPNLIDPLFYLLAMGF
                     GVGAYLTHVNGMLYRDFVITGLIAATAMSAATAETTVNAFIQYKIEKTYDAMLMTPIN
                     TNDIVVGQAIWAGIRAVIFGGIFWLISMLITAHFHVLMLLIPLILFIVGYLFGVLGLI
                     FTYLAPSREFLNYYNVLVIRPLYMFSDTFFPITSLPPILGDLTWFSPLYHATRMIRII
                     WGGEVTGLYLHLIWLIALALLITVLPMYMLHRRYYR"
     gene            16880..17671
                     /locus_tag="VXB91_001354"
     CDS             16880..17671
                     /locus_tag="VXB91_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2785 domain-containing protein"
                     /protein_id="HEV0470800.1"
                     /translation="MYQDLLRKIAEEKPNYNQEEIQWLFDHLGNPSPEIRDDLVFTSF
                     AKEIQEELFTQEQFHFIAEVVLADGGLDKEIDKVGLSTLERSFRALIYANLLSADANQ
                     QSVFYQGLQSEIRNVLLNQGLHYLSKEKDTTGFSSQYGWVHSFAHGADLLTEVVCHPD
                     FPINRIHEVFDILGQLFKRMSILFTDDEDWRLARVIYEPILQGKLEQEQVASWIKTVD
                     FPIEEREDFYKFSNFRSCLVEVYVQLDQRNSLQDDLKEAIQSFQY"
     gene            17782..18450
                     /locus_tag="VXB91_001355"
     CDS             17782..18450
                     /locus_tag="VXB91_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin"
                     /protein_id="HEV0470801.1"
                     /translation="MKKFVAELIGTFMLVFVGTGAVVFGNGLDGLGHLGIAFAFGLAI
                     VVAAYSIGTVSGAHLNPAVSIAMFANKRLSSSELVNYILGQVVGAFIASGAVFFLLGN
                     SGMSTASLGENALANGVTVFGGFLFEVIATFLFVLIIMTVTSESKGNGAIAGLVIGLS
                     LMAMILVGLKITGLSVNPARSLAPAVLVGGAALQQVWIFILAPIAGGVLAALVAKNFL
                     GTEE"
BASE COUNT         5547 a         3160 c         4198 g         5678 t
ORIGIN      
        1 aaaactatat ctaaagggag gttaatctct ctctttattt ttaaaatttg aaaggaaaaa
       61 tacaaaaatg aaaattaatg aatatttatg gagaacgagc tgtcttatac tgctaattat
      121 catgagcttc tttgcaggct tcggagctaa attagagttt acatcttata acccgttttt
      181 atctgttaaa tttggtttgg tcgtagctct gacagtcttt gtagttcaat tgttagccat
      241 actgccagcc atggttaaaa gaggaaataa aaatgagaat gttgaatcaa acaattcgtg
      301 tgaagagtaa atacccttac ttgattcgtc cccgaaatat taaaattgta agattgttta
      361 tccaaatttt tgtcttttta ctcttaatat cttcgtggat tgctataatc ccatttattg
      421 ctcgtctagt cttttccatg ttttttataa gtcttctttt tttcgtagag aagttctttc
      481 gttctaattt tatagcaaaa ttgagaaaca agctcaatat cagagaagcc ttgttttaca
      541 tgttaattag tttaaattta tatgatgagc tcgataatga agtagtagat acagcagttt
      601 tatattttga cgttgagaat aataaagttg ttgtctgtgc cccactattt gggaaccgtt
      661 atctgaaaac cttgaaaaat ttagaggaat atctctgtcc cactttgggc ttgtccttgc
      721 tgtctaaaaa agaagaaatc gataaaatag tatacgtgtt agggcagaaa gaagaaatag
      781 aacaatatgt ttttaatagt aacacattaa caagagaatt ttttaaagat attcctagtt
      841 caataatcaa gctgtcaaat acacagaaat ttagtctaaa gtccaacact aacctaggta
      901 tatatggaag aacggggaca ggcaaaacaa tagctctgca atggtactta tttaacgcac
      961 tggctaaagg ttgtggtatt gctgataata cttatttagg catagtagat ggtaaggcag
     1021 ctgacttgta tcgtattggt gaacttcttc acgaagaact gggagaacaa gtggcagtag
     1081 gctcttcacc acaaatgctt gcccaattat cgagaaaatt cattgagaat atggatgcaa
     1141 gatttaaaat tatcaaacag aatagttcat tgaatgctga catttatgag ctagatgagc
     1201 tgggactggt acctaatttt ttgttcgttg atgaactcgc ttctattcgt gatagttgtg
     1261 gctctacgaa acaaggtaga gaaacatgga atgaaattct acaaaattta ggcttgattg
     1321 cacgcaaagg acggcaggca ggttgccacc tagtcctatc tactcaagac cctaatgccg
     1381 aaaacatccc cgttgaattg aggaatcaaa tttcagcagt tttatacctt ggtgccccag
     1441 gggctgatag attgaagatg gcttttagca tgtgcgaatt agaaaacgtt cctacagttt
     1501 cagatagaaa aggggaggct ctcttttatg ctgatgggct taatacagta gagccagtgc
     1561 taacaattgt gccatttgtt gatttaaaaa ctaagaaaga gtttttaaat gtagttagaa
     1621 acatactgcc aactaatgac ggtcttcctc ccctagcgaa atagggcgat tgccggaggc
     1681 agaatcgagc ggagcgctct cttttcgcta ggggagggag agccaaccga ctgctttgca
     1741 ggaggtcaga aaaaacatcc ccagtactaa tagggggtgc acacatacat gaaatgtact
     1801 ctaaaccctt gatacgtgag gggttacggc ttactagttg caccaagggg tcgcaaactc
     1861 ttgggagagt agggatgaga ggtgtttcca tgtatgatac ggaattaaag gagaaaaata
     1921 tggtttacaa tatgacagat acaaacatta aaattggatt gcttgacctt gagatgtcac
     1981 agtttgatat tcctaagaaa gtagtgattt tatcagttag ggtgaacaat aaatacaaag
     2041 aagtcaacgg cgaaaacgtg aagacagatg aagtaagtaa aattacttct gctgttcttg
     2101 acgctgacaa agtgaaagtt ctaactgaaa tgggaatttc tactgatgac ttaaaagcta
     2161 ttaacctaga aattatcgga aatctagata agattgcaaa acttgctcaa aatgatgctt
     2221 tgttgaatgt tcctgttgaa ttgattcggc ctaaagttcg actagcttgg aacatggcta
     2281 ggaataattg gtctggtgta aaaattgtgt gtgaggatat taaagttcta ggagaataat
     2341 cctatgaata cagttagaat agattatttt gctgtgacag ttaagaatat ttcgccagaa
     2401 aaagttctga cagacatcct tttgattcct cttgaaaact ttaccttgaa tgattggggc
     2461 ataaataagt ataagcaaca ttattcttgt tcagaaatta aggtgtattt taatgctgat
     2521 aggctttcta tgggtgtatt tattgaatta aaagggcaag gttgtcgtca atatgaagaa
     2581 tttttaaaca gtaacgaaaa taattggatt gctttgataa gtcgtttata tcatcataat
     2641 gccaacttta ctagactaga tattgcccac gacatatttg acggtagctt agatgttcaa
     2701 cgaatatatg actattgcaa gaaaggatta tgtatctcga aagcaaaaca ctttgaatat
     2761 catgagaaat cagttctaga ttctggtgag cgtgtaggag aaacagttgc aataggttca
     2821 cgaggtaatc agcagtggtg catatataat aaacgcatgg agcaacttgg taagcaagag
     2881 cttgtagaag tttcatcttg gactcgcgca gagcttagat gttggcagga gaaggctaat
     2941 ataattgcag agcagttata tttaaaacgt cccttatcgt caatatattt tgaggctatc
     3001 aacggtcatt atcgctttat tcgtccaaat gctatagata gtaatcgttg gagaagaaaa
     3061 aaggttgagt ggtgggtaaa ctatctaggg acagaaaatc agacagttct gagtattaca
     3121 agggctaaga cgacgttacg ggagtctgaa gtttggactg agaaacaggt tgcaaaaaca
     3181 ttagcaaaag tctatattgc aaagtatcag gcctatgatg ttcaaaaggc ggaagattat
     3241 attcaaaact tgctcaaaga gggactttca aagctaactg ataatgatga aaaggatata
     3301 gaacaatata taagagaaca gaatagttcc caactttggg gaaccgatgg aaggagtgac
     3361 tgacatatgg cagatactat atcaaataag gatttgattt ccatgggcta taggccatca
     3421 acagctaatg ctattatcca tcaggcgaga gaattacttg tatcacgagg ctatacattt
     3481 tataatcgca aacgtttgat ggttgttcca aaaagtgttg tgaaagagtt gttgggaatg
     3541 gaattgtgaa atggcttata tcgagtataa acagcgtggt aagaaaagac tttggtcctt
     3601 ctctatacga gaaaggagca agagcctact ccataaaagc ggatttaaaa caaaacgaga
     3661 agctaaaata gaagcggaga aagttcttca taagttaaat actgggagtg tcttaagctc
     3721 tagtatgact ttatcggagc tttataatga atggcttgat ttaaaaattt tacctagcaa
     3781 tagaagtgta gttactaaaa aaaaatatct catgagaaag aaggtcatcg aaaggttatt
     3841 tggaaataag cctgtatcac aaattaagcc tagcgagtat caaaaaatta tgaatgagta
     3901 tggagagact gtatcgagaa atttcttagg aagattgaat tcttgtattc gggcaagtat
     3961 acagatggct attgctgata aggtgataat agaggatttt actgcttatg ttgagttgtt
     4021 ctcttctaag agtggacaaa aggttgagga aaagtatttg catgctgagt cagattatca
     4081 aaaagtttta gtatatttga aaaataagtt tgattatcaa aaatctattg taccgtatgt
     4141 aatttatttc ctttttaaaa ctggcatgcg tttctccgaa ttgattgctc taacttggga
     4201 tgaagttgac gagcttaatg agcaacttaa aacttatcgt cgttacaaca ccgctattca
     4261 taagtttact ccacctaaaa acaatacttc aataagatta gttcctatta cttcagatat
     4321 gctttccttg ttaaaaacat tgaaaatatt gcaattaaaa acaaataaag aattaaatat
     4381 tgataatgaa aataatttga tttttcagca ttttggctat gtctacgatg ttccagatat
     4441 tgcaacagtc aataaagcta taaaagtaat gttgaaggaa ttgcaaattt ttccattgat
     4501 tactaccaaa ggagctagac acacttatgg tagttattta tggcataata atattgattt
     4561 gggagttata gcgaaaattt taggacataa agatatctcc atgttgattg acgtttatgg
     4621 gcataccttg gaggaaaaaa ttagtgaaga gtttatggct gtgaaaagtt tgttgtaaaa
     4681 acacggcaaa ttgcacgaca atttttaaaa ggaaggcaaa aaaagcccta tattataagg
     4741 cttttcctgt tgtatttata tgccccctac agggatcgaa cctgtgaccc acggattaag
     4801 agtccgctgc tctgccagct gagctaagga ggcaaagaaa aaagctgtat tggtgccgaa
     4861 acttcacggt ttgtattgaa cccgcgcaat taagcaggtg ggcaactcgc tctaactgaa
     4921 gctgtttccg tgtgagacgg cctacatgct gttagaagac ttttgtttcc ctaataatac
     4981 aaaaaatagt cggtcaacac ttaagtgtga agtcgtacac cacagcgttt ctatacttat
     5041 atgataccac tttttcaaaa aaaatcaaga ggaaagtgca attttttgaa aaggatttca
     5101 gatttttcgc aaacggtcga tagcttcctt tctttgagcc aaagcccgtt catatttacc
     5161 agtatcttct gcttggaaat agtgatgatt acgaattttt tctggcagat agtcttgctt
     5221 gacccaattt ccaggatagt tgtgtggata gagatagtct tgggcattcc ccagttcctt
     5281 gcttccactg tagtgcccat cacgtaggtg tcgcggaata ggcaagtgcc ctgatgtttt
     5341 gaggtcagca agtgccttat ccatagctac ataggctgag ttggattttg gagaaagggc
     5401 caaatcaatc acgacattgg caatgagaat gcgggcttct gggaacccaa tcttctgggc
     5461 agcatccaga gcagtcacgg tatgaatctg ggcctcagga ttggctaagc cgatatcttc
     5521 ataggcgata acagtcaagc gacgagcgag actaggcaga tccccagcct caatcaagcg
     5581 ggcagtatag tggagactgg catccacatc tgagccacga atagactttt gcagggcaga
     5641 tagaacatca tagtgaccgt ctccatcctt gtccatagtg atgtagcttc tctgaagact
     5701 attttccatg atgtctaagg tgatgtggcg aatgccctcg tcattctcag gggtagagag
     5761 aacagctaag tccagtgagt taaaggcaga gcgaaggtct ccgtttgtag aggttgcgat
     5821 gaaatccagc gcatcctcat ctagttctat tggaaaatca aaaccacgtt cagggttact
     5881 tagagctatc tgcagggcct ctttgacgtc ttggttagac agaggttcca actcgaaaat
     5941 ttgaactcgg ctacgaatgg caggagtgac agagaagaaa ggattttcag tcgttgctcc
     6001 aatcatgatg accagtccac tttccaagag aggcaagagg aagtcttgct tggtcttatc
     6061 tagtcgatga atttcgtcta gcaataggac gagaccacca gaaaatttag cttcttccga
     6121 gatttcttgc agtcgctttt tactatcaac tgtcgcattg aaagttcgaa aggcatactt
     6181 ggtcgttcca gcgatggcag aggcaatact ggttttgccg attccaggag ggccatatag
     6241 aatcatggag gacaggcggt tggcttccac catgcggcgg atgatttttc caggtccgac
     6301 cagatgctcc tgaccgatga cctggtcgat ggttttaggg cgcatgcgaa gcgcgagatt
     6361 gtctggcata gcagtccttt ctagcgtgga tttgagtaga atgactcatc tactatatct
     6421 tactatgtcc attctagcct attagttgtg atatttcaat ggttttgtaa taatcaggga
     6481 gtgagataga atctttttta ctatttaatt taatgaggag aggtatcagc atgagagatt
     6541 tgattttcct taaagctcaa aataggatag ttgagcctaa agaagtggaa gtgctgactt
     6601 gagaaataat attgctgaat gtcattgtat gaactataat gaaaagagag gtgataagca
     6661 atggaaatga tggaccaagt caggaaattt tgatttttac aaaacaaatt cgtcattgga
     6721 ttcttagtga tcaagttatt tcagggaaaa gaaaactttt cttccgggaa gatactccaa
     6781 aagagatttt agatttgtac gaaaacatta aatctaaact tgattttgct taccaataag
     6841 tttattctaa taatgggttg aaaaaatatg aaaaatagaa taattgatgt ttttgaagta
     6901 gtaaatcgca tccttgtaat aactgttgaa aatcctgatt tcgaagactt gagagttaat
     6961 catactcaat gaaaatcaaa gagcaaacta ggaaactagc cgcaggctgt acttgagtac
     7021 ggtaaggcga cgttgacgtg gtttgaattt gattttcgaa gagtatcagt ttgtaaaaat
     7081 tggagataaa aaatatagag tacgcagtgt tcctatgatt cattcaactc cgcctcaatc
     7141 tgtcttagat cgagatactt ttacaattga ctatacagat gatgaattgc tcgataaaga
     7201 agcagttttt actactcatt agaaaaatag gtctgaataa attggcttcc cttagaacca
     7261 catctagggg cttttatgta taatagaata ataagtatca ctcctttaca atacgtgtaa
     7321 cacgtgttat aatggtgttg tcaggaggta aaagcgctat gcctatgaca caaaaagaga
     7381 tggttaaact ccttacggcc catggttgga taaagactag aggcggtaaa ggctcccata
     7441 ttaaaatgga gaagcaaggg gaaagactta tcacaatccc tcatggtgag ctgaataagt
     7501 acactgaaag agggataaga aagcaagctg ggttgtaaaa ttcagcccct gttttttgat
     7561 atggaggtag tgaaatgtta gttacgtatc cagctttatt ttattatgac gacacagacg
     7621 gaacagaagc gacttatttt gtccatttcc cagattttga atactcagct acacaaggag
     7681 aggggatttc tgaggctttg gctatggggt cggagtggct agggataact gttgcagatt
     7741 tgatagagag tgatggagag ttacctcagc catcagatat caatagcttg tctttaattg
     7801 ataatgatcc ttttaaagat gatgaagatt tcgtgtcaac ctatgacctt gataaatctt
     7861 ttatttctat ggtatctgtt gatgtatcag aatacctagg aagtcaggaa cccataaaaa
     7921 agactttgac cataccaaaa tgggcagata agttgggacg agaaatggga cttaactttt
     7981 ctcagacttt gacagacgct attgcagata agaaagttca agcctaagat taagcgtggt
     8041 atcgtggtaa tagtcaataa aaaagcacgt ccacttgtgc tagttactcg cctattgatt
     8101 ttatagattt attagccctt tcgcgggctt tttatattga tttttatgag aaatgaagaa
     8161 atcagacttt taagaaaatc actgatacca agggtttaaa tgaggtaata tggtataatt
     8221 aggacataaa ataattttgt ggtaagatgg tagtatctat tttagcatat ttccgagcaa
     8281 tcggggcgat taaagagtcg catagaaaga ggacaaaatg gcaacatacg gatttttaga
     8341 tgttttagag gaagagttgg acaagaactt tccctttgac tttgagatta gctgggacaa
     8401 acgcaaccat gcggtagaag tgagttttct attggaagcg caaaatgctg caggtgtgga
     8461 gatggtggat gaagacggag aggttttatc agatgacatt ctttttgagg aagcggtcct
     8521 tttctacaat cctgccaagt caacagtcaa tgaggaagac tatttgactg ttattcctta
     8581 cctgcctaaa aaaggatttt cccgtgaatt tttagcttat tttgcgcttt tccttaaaga
     8641 tactgctgag gttgggctag atgtcctcat ggactttttg gaagacccag aagcagagga
     8701 atttgtcatg gaatggaacc aagaagtctt tgaagaagga aaagttggct tggaagaggg
     8761 agaattttat ccttatccaa gatactagga gttggttgga ggtgttatga agaaaattgg
     8821 gacttatttg gtttatgtgc tagcttttgt ctttattatg ctagcttttg cttgtggaac
     8881 aatcgcattt gcagagttgg ggtattccgc agttttagcc tttacttttg gttatgcctt
     8941 cgctcttcta agcatgtatt taatctttat tcttcatgag ctgggtcatg ctttttgtgg
     9001 ctacttgaca ggctatcggc tggtggcttt tggattagga cattttattt tgaccaaaaa
     9061 gtcaggcagg tttcatctta gtagaacagc cattctgaaa aatgttggtg ctcaatacat
     9121 tggtttaaaa gaggatgaaa gcgatcaaag aatcatcctg atgctttcag gaggcttgat
     9181 ggttcatctc ggcttgatat tattggcgat agtgtttgga tttttgacaa gaagctggta
     9241 ttttgcaggg acttggattt ttcttaattt atctttcttc ctaaataaca ttttgccagt
     9301 cgacatcacc gatggagcaa aaatttggga attactacaa caccctgaaa ataccaaata
     9361 cgcctacctg gtattgagac attctgctca aactttgctg gctcctcaag aatatgattt
     9421 gaaagacttt gttcaagcag ttcctgagga tgcacgaggg agttttgcgg atggtgtatt
     9481 aggtatgcaa ggtgaagttt ccattttgga agggaaggaa gaagtagcta aacagcagtt
     9541 tcaagcatta cttgagagga caactactcc gatgatgcag acagttgccc aactatccct
     9601 gcttcatatc gccttgttgg aaggagattt tgagcaagcg gagcaatatg ctagtattcg
     9661 acaggtcaaa tcgtttctgt ctctcaaact gtccaatctt caagtgatac aagcttggta
     9721 tcaatttaag gtaaagaaag atgtagatcg aactcgtaag gctctcaaga ttgctagaca
     9781 gaaaatggat agtagtcgaa tgttgaggga cgagaaacgc tattatgaaa acttgttagc
     9841 agagctggaa aaggaaatgt tagaaggaac tgaagatgga actagaaatt tctgatttcc
     9901 caggctgtaa gattgctttg ttttgtgggg ataagctctt gactatctta cgtgatgata
     9961 aggcaagtat tccctgggcc aatatgtggg aactgccagg tggtggacgt gaaggtgatg
    10021 aaagtccttt tgagtgtgta gcgcgtgaag tttatgaaga actgggcatt catctgactg
    10081 aagattgtct gctttggagt aaggtttacc caagtatgct ttttgcagac aaacagtccg
    10141 tttttctagt tggtcagttg acacagaacc agtttgacag tatcgtattt ggagatgaag
    10201 gacagggcta tcagctgatg aatgttgagg aatttcttag ttccagtcaa gttgtccctc
    10261 agttgcaaga gagattaaaa gattatttaa aagtaagtga ttagaaagga tggttcagtt
    10321 aaatttctaa actgaacccg ccctaaacac tgtgccaaaa agataaactt ctcttagaca
    10381 caagcgtctt cagagaattt cctattttgg ttttgtgttt tacgggcttg gtatcttaat
    10441 aatggaaaca tggcaagagt taaaagttac agtgaagcgt gagggagagg agttggtttc
    10501 caatctcttg attgagctgg gagcgcaagg agtcgcaatc gaagacagta tggactatgt
    10561 gggaaatgtt gaccgctttg gcgagatttt cccagaggtg gagcagcaag aagaaatcgt
    10621 tgtgacagcc tactaccctg acacggtgga tgtgacagtg gttgaggcgg acttgcaggc
    10681 tcgcatatca gaattgacgg attttatgga tttgggagag ttaaaaatag gtacgactgc
    10741 cttggctgag gaagactggg cagacaactg gaagaaatac tatgagccag ctcgtatcac
    10801 tcatgatttg accatcgttc cctcttggac agactatgag gcgactgcgg gagaaaaaat
    10861 tatcaagctg gatcctggca tggcttttgg tactggaacc cacccaacta ccaagatgag
    10921 cctttttgcc ttggaacagg ttcttcgtgg tggcgaaacg gtgctagatg tggggactgg
    10981 ttcaggggtt ctctctattg ccagctcgct tctgggggct aaagaaattt tcgcctatga
    11041 cctggatgat gtggcggttc gtgtggctca ggaaaatatt gagctcaacc ctggcatgga
    11101 aaatatccat gtagcggctg gagatttgct taagggtgtg gaaattgagg cagatgtgat
    11161 tgtggctaat atcttggcgg atatcctcat tcatctaata gacgatgcct atcgtttggt
    11221 taaagacgaa ggctacctga tcatgagtgg cattatcaag gacaagtggg acatggtgcg
    11281 ccagtcggct gagtcagctg gatttttcct cgaaactcac atggttcaag gggaatggaa
    11341 tacctgtgtc tttaagaaaa ccaaggatat ctctggtgtg attggaggct agcatgcagc
    11401 agtattttgt aaaaggcagt gctatctctc ctgtcactat cgaggacaag gaaaccagta
    11461 agcatatgtt tcaggttatg cgcttgaaag aagaggatga ggttacctta gtctttgatg
    11521 atggcatcaa gcgcttggcg cgcgtgctgg atatggaaaa tcgtcagttt gagttggtcc
    11581 aagaattaaa tgacaatgtg gaactaccag tccaagtgac catcgcatct ggatttccca
    11641 agggagacaa gctggagttc atcgctcaaa aagtaaccga actgggtgct agccaaatct
    11701 gggcctttcc tgcagactgg tcagttgcca agtgggatgg caagaaattg ggtaaaaaag
    11761 ttgaaaaact agaaaaaatt gcccttggag cagccgagca aagcaagcgt aatattgtac
    11821 caagtattaa acttttcgag aaaaaagcag attttctagc tcagctggac cagtttgact
    11881 ttatcatagt agcctatgaa gaatcagcta aagaaggaga agccgctgcg cttctgcaag
    11941 cagtcactgg tcttgaaaca ggagccaaac tgctctttat ctttggtcca gaaggcggtc
    12001 tctcacctgc agaaatcgaa agttttgaag ctaagggagc cgttttggta ggcctaggtc
    12061 ctcgtatttt gcgagcagaa acagcaccgc tttacgcctt atcagccctt agtgttttag
    12121 tagaattaga gaaataagag gaagaaaatg gaacaaaaac accgttcaga atttccagag
    12181 aaggaactct gggacttaac agccctatac caagaccgtg aggatttctt gcgtgcaatc
    12241 gagaaagctc gtgaagacat caaccagttt agccgtgatt acaagggcaa tcttcacact
    12301 tttgaggatt tcgagaaggc ctttgcggaa ttagaacaga tctacattca gatgagccat
    12361 attggcaact atgcttttat gcctcagacg acggactata gcaatgacga atttgccaat
    12421 attgcccaag ctgggatgga atttgaaaca gatgccagcg tagccttgac cttctttgac
    12481 gatgccttgg tggtagcaga cgaggaagtc ttggaccgtt tgggtgaatt gcctcacttg
    12541 acggcagcta ttcgtcaggc caaaatcaaa aaagcccact atctaggggc tgatgtggag
    12601 aaggccttga ccaatctcgg tgaagttttc tatagtccgc aggacattta tactaagatg
    12661 cgagctgggg attttgaaat ggctgacttt gaagcccatg gcaagaccta taaaaacagc
    12721 tttgtcacct atgagaattt ctaccaaaat cacgaggatg ctgaggttcg tgagaaatcc
    12781 ttccgttcct tctcagaggg acttcgtaag caccaaaata cggctgcagc agcctatctg
    12841 gctcaggtca agtctgaaaa actcttggct gatatgaagg gatacgactc tgtatttgat
    12901 tatcttctag ctgaacaaga agtggaccgt gtcatgtttg accgccagat tgacctcatc
    12961 atgaaggact ttgcaccagt cgctcagaga tacctcaagc atgttgccaa ggtaaatggt
    13021 cttgaaaaga tgacctttgc agactggaaa ttggacttgg acagcgccct gaatcctgaa
    13081 gtgactattg acgatgccta tgatttggtc atgaagtcgg tagaaccttt ggggcaagaa
    13141 tattgtcagg aagttgctcg ttaccaagaa gagcgctggg tggactttgc tgctaacagt
    13201 ggcaaggatt ccggtggtta tgcggcggac ccatatcgcg tacaccctta tgtactcatg
    13261 agctggacag gccgtttgag cgatgtctat accttgattc atgaaatcgg gcattctggt
    13321 caattcatct tttcagacaa tcaccaaagc tatttcaacg cccacatgtc gacctattat
    13381 gttgaagcac cgtcaacctt caatgaattg ctactcagtg attacttaga gaaccagtct
    13441 aatgacccac gtcaaaaacg cttcgctctg gctcatcgct tgacagacac ctacttccat
    13501 aactttatca cccacctctt ggaagccgcc ttccagcgta aggtgtatac attgattgaa
    13561 gaaggggaga cctttggagc aagcaaactc aacagcatta tgaaggaagt tttgacagat
    13621 ttttggggcg atgccattga aatcgacgac gatgcagctt tgacttggat gcgccaagct
    13681 cactactata tgggcttgta tagttacact tactctgctg gtcttgtcat ctcgacagct
    13741 ggttaccttc atcttaaaaa ctcagaaact ggagctgaag actggctcaa tctcctcaaa
    13801 tcaggtggta gcaagacacc acttgagtca gccatgatta tcggtgctga tatttcaaca
    13861 gacaaaccac tccgtgatac catccaattc ttgtctgaca cagttgacca gattatcgcc
    13921 tacagtgctg agttggggga gtaaggggat agagaggttg ttatagaatg ggtatggaca
    13981 gttatttgct taaaagtcca tgtttaaatc ccccattcct tttcgaggaa ttctttgccc
    14041 tgctctgtaa tggtaagtga acgtggcgtt tgtgcaggga tgaccaattg tttttcactg
    14101 aaaaattcta aaagagcatt gccgagagct ccgccgacat gatttttacg ttcgctccaa
    14161 tccaaacatt tagggcaaaa tttccgtttt ttctttttca attcatccgt atcaatgtgt
    14221 aatttttttt ggaaataaga cttcccagct tcagtgagtt ggaagtcttt ttctgattcg
    14281 ctgaggagat tttcttgcaa gagataattg gtaatggaaa tgccaagctc accagcaata
    14341 tggtcatagc aggtgcgagc gacctttaat tcctttttgt gaatgtgttg tttataactt
    14401 ttgacatcac gctgaggaga gtagaagctg agaaattcca gcatttctgc aatggcagca
    14461 ctttttaaag aataataatg aaaacgtcca taggtttgta gagtggttac ctgcgcttcg
    14521 gtaagtaatt tgaggtgata gctgacagta tgttgcttga ttttggtaaa gctggcaatt
    14581 tcgttaaccg tgtgagcttt tccatccatt agaatatcta aaatgtgcat ccgagaaggg
    14641 tctgataaga gttttgtgat gatgaaaata tctggttcca taaaaatttt ctccaaattt
    14701 catatatcga ttattttcta tcttttatta tactataatc aaagcacaag aaaaatagat
    14761 tttaaaaatg ttttactaga gaatatttta aattttattg tctgagttta aatggaggta
    14821 aaattacaaa agtaattgca gcagtatcca cagttgaagg acgttaatct taagattaca
    14881 ttctcaacat tttttcaaaa gtgagatgaa ttaacaaagt atccaacatg ctctatttgt
    14941 tggggaaaga aagagtgaag aagttaagtg ttaaaaatct aaaaaagcaa tatggttctt
    15001 atgaagctgt caagggaatt agctttgaat tgggagaagg agagtgtttg ggtatcttgg
    15061 gaatcaacgg tgctggcaaa acatccactt taaagatgat ttactcactg acctcaattt
    15121 cctcaggaga gattgatatc ttggggcaaa atattgaaac caatcgtcgt aagagtaaat
    15181 cttgtctggg tattgtaggg caggaggata tgctggatat gaccttgaat gtttatgata
    15241 atctttttgc tcacggtcta tgttatggta tctcatctgt cgaacttagg aagagaatcg
    15301 attttctctt ggattttgtt caactgagca aacatgcgca aaagatggtg aatcagctgt
    15361 cgggtgggat gcgacgacgt cttgtcttgg caagagctct catcaatcgg cctgatatta
    15421 tcattttaga tgaaccgaca gttggtttag acattcaatc ccgcaatatt atttgggata
    15481 aacttttgga gttgaaggaa ttaggtgttt ccatcattat tacttcccac tatatgaatg
    15541 agattgaata tttgacagat agggtgctga tgctccacca agggactatc aaagaagaag
    15601 gaactgtaga agacttgctc atcaagtatg atgctgacaa ccttgagacg ctttttttgg
    15661 ggttgactgg gacagagaag gaggacttgc atgtttaagt tatcatttca ctccatcgga
    15721 cacgttgtgg tacgcaacta catgagtttt agaaatttat ttaaaatttc aattgtcccc
    15781 aaccttatcg accccctctt ttatctttta gcaatgggat ttggagttgg tgcttatttg
    15841 acgcatgtta acggtatgct ctaccgtgat tttgtcatta caggtttaat tgctgcgact
    15901 gccatgtctg cggccactgc agaaacaacg gtcaatgcct ttatccagta taagattgaa
    15961 aagacttatg atgctatgtt gatgacgcca atcaatacga atgatattgt ggtgggtcag
    16021 gctatctggg caggtattcg tgcagtgatt ttcggtggga ttttttggct gatttccatg
    16081 cttatcacag cgcattttca tgtcttgatg ttattgattc ctctgatttt atttatagtg
    16141 ggttatttgt ttggtgtttt gggactaatc tttacctact tggcgccgtc tagggaattt
    16201 ctgaattact acaatgtttt ggtaatccgt cctctttata tgttttcaga taccttcttt
    16261 cccattactt ccttgccccc aatacttggt gatttgactt ggttttctcc cttgtatcac
    16321 gctacccgca tgattcgtat tatatgggga ggtgaggtga caggtttgta tcttcatctt
    16381 atctggttga tagccttggc gctcttgata acggtgcttc ctatgtatat gttacatcgt
    16441 agatattata gatagtctaa ttatttgtga tgttgtagtc atattctaat ttatactaaa
    16501 cgttattcga atttggacag gtatgggaac tgtgcctatc aatattgtaa tttatggaag
    16561 ttgaaatagt acggttcagt ttttaaaata ttgttagaaa ttgttttaaa ttccctaatc
    16621 aatttgtata gtttttattt cactttatta taactagttt ttcgcaattt ttgagacagg
    16681 aatgtgattt ttgtgataag gctctatcat tacaagttca tttgtggtca tatggaataa
    16741 atcatttata tatcttttca gaaatatgct gtttctctga atataaatgt ctttttcttt
    16801 ttaacttaat tttacaaatt ggtaaagtca tttaagactg cctttttgaa cagttgctag
    16861 aaatgtagag gtattgacca tgtatcaaga tttactaaga aaaatagcag aagaaaaacc
    16921 aaattataac caggaagaaa tccagtggtt gtttgatcat ttgggaaatc cttctccaga
    16981 aattcgtgat gaccttgttt ttacaagctt tgctaaggag attcaggaag agctatttac
    17041 acaggaacaa tttcatttca ttgctgaggt ggtcttagct gatggagggt tagataaaga
    17101 gattgataag gtaggcttgt caacacttga acgttctttt agggcactta tttatgcaaa
    17161 tctcttgtct gcagatgcta accagcaatc ggttttttat cagggattac aatcagaaat
    17221 tcgtaatgtc cttttaaatc aaggcttgca ctatctttca aaagaaaagg atacaacagg
    17281 tttctcaagt cagtatggtt gggttcattc ttttgcacat ggagccgatt tactgacaga
    17341 ggtggtctgt catccagact ttcctataaa cagaattcat gaagtatttg atatacttgg
    17401 ccaactattt aaaagaatgt cgattctctt tacagatgat gaggattggc gtttagcaag
    17461 agtgatctat gaacctattt tacaagggaa gttggagcaa gaacaagtag cttcttggat
    17521 aaaaactgtt gattttccga tagaagaaag ggaggatttt tacaaatttt ccaactttag
    17581 atcctgtctg gtggaagtct atgtccaact tgaccagaga aatagtttac aagatgacct
    17641 gaaagaagct atccagtctt ttcaatacta gggattagct aatagttcta tgattttcaa
    17701 aaaatttcca atcaattttc ttgaaaccct ttcctacttt tgatagacta gtatctagtt
    17761 tttgaaaaaa ggagaaagaa aatgaaaaaa tttgttgctg agttaatcgg tacgttcatg
    17821 cttgtgttcg ttgggacagg agctgttgtt tttggaaatg gtcttgatgg ccttggtcac
    17881 cttggaatcg cctttgcctt tggtttggca atcgtggtgg cagcctactc aatcggaact
    17941 gtttcaggtg ctcacttgaa cccggctgtt tcgattgcta tgtttgcaaa caaacgtttg
    18001 tcatcttcag aacttgtaaa ctacatcctt ggtcaggttg ttggagcttt catcgcttct
    18061 ggcgcagtct tcttcctctt gggtaattca ggtatgtcaa ctgctagtct tggtgaaaat
    18121 gccttggcaa acggtgtcac tgtctttggt ggtttcttgt ttgaagtcat cgcaactttc
    18181 ttgtttgtct tgattatcat gactgtgact tcagaaagta agggcaatgg cgcgattgct
    18241 ggtttggtaa tcggtttgtc attgatggcg atgattcttg tcggactgaa gattactgga
    18301 ctttcagtaa acccagctcg tagcttggca ccagctgtct tggtaggcgg cgcagccctt
    18361 caacaagttt ggattttcat ccttgcacca atcgctggtg gagttcttgc agcccttgtt
    18421 gcaaaaaatt tccttggaac agaagaataa ttgaaactca aaaagccttg ctcctcatct
    18481 tgaggaacag ggctttttcg tatgatactc ttcgaaaatc tcttcaaacc acgtcagctt
    18541 caccttgccg taggtatggt tactgacttc gtcagtttca tct
//
LOCUS       DAVLBE010000035        17518 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.035, whole genome shotgun sequence.
ACCESSION   DAVLBE010000035 DAVLBE010000000
VERSION     DAVLBE010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17518)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17518)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17518
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.035"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(565..1701)
                     /locus_tag="VXB91_001356"
     CDS             complement(565..1701)
                     /locus_tag="VXB91_001356"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HEV0470802.1"
                     /translation="MKHSVHFGAGNIGRGFIGEILFKNDFHIDFVDVNNQIIHALNEK
                     GKYEIEIAQKGQSRIEVTNVAGINSKEHPEQVIEAIQKTDIITTAIGPNILPFIAELL
                     AKGIEARRVAGNTQALDVMACENMIGGSQFLYQEVKKYLSPEGLTFADNYIGFPNAAV
                     DRIVPTQSHEDSLFVMVEPFNEWVVETKRLKNPDLRLEDVHYEEDLEPFIERKLFSVN
                     SGHATSAYIGAHYGAKTILEALQNPNIKSRIESVLAEIRSLLIAKWNFDKKELENYHK
                     VIIERFENPFIVDEVSRVARTPIRKLGYNERFIRPIRELKELSLSYKNLLKTVGYAFD
                     YRDVNDEESIRLGELLAKQSVKDVVIQVTGLDDQELIEQIVEYI"
     gene            complement(1763..2200)
                     /locus_tag="VXB91_001357"
     CDS             complement(1763..2200)
                     /locus_tag="VXB91_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0470803.1"
                     /translation="MKLEKHLIKLNKQFSNKEEAICYCGQVLYEGGYVNEDYIEAMIE
                     RDKELSVYMGNFIAIPHGTDAAKNDVLKSGITVVQVPRGVDFGNVSNPQVATVLFGIA
                     GIGNEHLEIIQKISIFCADVDNVLKLADAQSKEEVLRLFDAVE"
     gene            complement(2202..4157)
                     /locus_tag="VXB91_001358"
     CDS             complement(2202..4157)
                     /locus_tag="VXB91_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEV0470804.1"
                     /translation="MLLTKREEQLLKAFLHVGKLSMQDMTEILQVSSRTIYRTLSDLT
                     DSMEQYGIEIMKHGKYYILTGELDDLPTELEVLVEYSPQERQELITYRLLTESGFVTN
                     EALQECTKVSNVTIIQDISDIDKRLLDFDLKIERQKGYRISGDSVGKRRFLAILLTNC
                     ISVADFSTGNFGSFDILEADRTRLASQIVNKQLSGFPDMDARMKMFFAILLSLIGQEQ
                     NIENSPNTSKQALEISQKIFQTYSKQTAQFYSIQEIIYFASILDELIIKRQDNPLFTE
                     KFDGEFFYNISNLIDTVSMYTKIDFFKDKVLFNFLFHHIRLSLGVPILFQGENLPESV
                     QILVERNKFLYTVISLLVNDIFPKYLHTEYEYGMIALHFISSLGRSPEIYPVRVLLLT
                     DERRVTRDLLVSKIKSVAPFVELIDIQSLVDYHSIDLSQYDYILSTKPLTNQEIDVIS
                     SFPTVKELLELQERLQYVQAHRTIVARDAIAPEKSYDLQDYLISSSQLLSQFELVQLE
                     NNQSFEHTVEQIIQYQKNVSDRDYLTRKLLSHFQNSPMAIPNTGLVLLHSQSSKVTTN
                     SFTMFELKLPISALSMKREEEEVKRCLLMLMSKEASEEARDLMTAISQSIIENHLYTE
                     IYKTGNQSIIYQMLNTIFNEKIKKLEN"
     gene            complement(4181..5950)
                     /locus_tag="VXB91_001359"
     CDS             complement(4181..5950)
                     /locus_tag="VXB91_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HEV0470805.1"
                     /translation="MEEKVSLKVRVQKLGTSLSNMVMPNIGAFIAWGVLTALFIADGY
                     LPNEQLATVVGPMLTYLLPILIGYTGGYMIHGQRGAVVGAIATVGAITGSSVPMFIGA
                     MVMGPLGGWTIKKFDEKFQEKIRPGFEMLVNNFSAGLVGFALLLLAFYAIGPVVSTLT
                     GAVGNGVEAIVNARLLPMANIIIEPAKVLFLNNALNHGIFTPLGVEQVAQAGKSILFL
                     LEANPGPGLGILLAYAVFGKGSAKSSSWGAMVIHFFGGIHEIYFPYVMMKPTLFLAAM
                     AGGISGTFTFQLLDAGLKSPASPGSIIAIMATAPKGVWPHLNVLLGVLVAAVVSFLVA
                     ALILHADKSTEDSLEAAQAATQAAKAQSKGQLVSTSVDAVVSTDSVEKIIFACDAGMG
                     SSAMGASILRDKVKKAGLEIPVSNQAISNLLDTPKTLIVTQEELTPRAKDKSPSAIHV
                     SVDNFLASPRYDEIVASLTGASPIAEIEGDIPTSAPVDSQEIDLNHIDAVVVAYGKAQ
                     GTATMGCETIRAIFRNKNIRIPVSTAKISELGEFNSKNIMIVTTISLQAEVQQAAPNS
                     QFLIVDSLVTTPEYDKMAARMYK"
     gene            6159..7498
                     /locus_tag="VXB91_001360"
                     /pseudo
     CDS             6159..7498
                     /locus_tag="VXB91_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(7626..8648)
                     /gene="cbpF"
                     /locus_tag="VXB91_001361"
     CDS             complement(7626..8648)
                     /gene="cbpF"
                     /locus_tag="VXB91_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpF"
                     /protein_id="HEV0470806.1"
                     /translation="MKLLKKMMQVALATFFFGLLGTSTVFADDSEGWQFVQENGRTYY
                     KKGDLKETYWRVIDGKYYYFDPLSGEMVVGWQYIPAPHKGVTIGPSPRQEIAFRPDWF
                     YFGQDGVLQEFVGKQVLEAKTATNTNKHHGEEYDSPAEKRVYYFEDQRSYHTLKTGWV
                     YDDGDWYYLQKDGGFDSRINRLTVGELARGWVKDYPLTYDEEKLKAAPWYYLDPATGI
                     MQTGWQHLGNKWYYLRSSGAMATGWYQDGSTWYYLDAETGDMKTGWQNLGNKWYYLRS
                     SGAMATGWYQEGSTWYYLNASNGDMKTGWFQVNGNWYYAYDSGALAVNTTVGGYYLNY
                     NGEWVK"
     gene            complement(8667..9488)
                     /gene="cbpG"
                     /locus_tag="VXB91_001362"
     CDS             complement(8667..9488)
                     /gene="cbpG"
                     /locus_tag="VXB91_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001100143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpG"
                     /protein_id="HEV0470807.1"
                     /translation="MNVEGRGSANFIKDNVLITAAHSYYRHDYGKEADDIYVLPAVSP
                     SQEPFGKIKVKEVRYLKEFRNLNSKDAREYDLALLILEEPIGAKLGTLGLPTSQKNLT
                     GITVTITGYPSYNFKVHQMYTDKKQVLSDDGMFLDYQVDTLEGSSGSTVYDASHRVVG
                     VHTLGDGANQINSAVKLNERNLPFIYSVLKGYSLEGWKKINGSWYHYRQHDKQTGWQE
                     INDTWYYLDSSGKMLTDWQKVNGKWYYLNSNGAMVTGSQTIDGKVYNFASSGEWI"
     gene            complement(9569..9808)
                     /locus_tag="VXB91_001363"
     CDS             complement(9569..9808)
                     /locus_tag="VXB91_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0470808.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LEKGPGSNDSSLSEISPTYGSYYQKQSEVLSVMMI"
     gene            complement(9958..10224)
                     /locus_tag="VXB91_001364"
                     /pseudo
     CDS             complement(9958..10224)
                     /locus_tag="VXB91_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060522.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            complement(10249..10560)
                     /locus_tag="VXB91_001365"
     CDS             complement(10249..10560)
                     /locus_tag="VXB91_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002877158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HEV0470809.1"
                     /translation="MDWDFADTCWEKEPRKYQYVAANYLKAMQSYLKETDLPKLEQLV
                     VTKSWWDTVDILDRVVGSLVYKHPELEEIILIFFENLFKPRQLYLQPQNSVLSNLRLA
                     S"
     gene            complement(10485..10716)
                     /locus_tag="VXB91_001366"
                     /pseudo
     CDS             complement(10485..10716)
                     /locus_tag="VXB91_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812384.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            complement(10717..11349)
                     /locus_tag="VXB91_001367"
     CDS             complement(10717..11349)
                     /locus_tag="VXB91_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0470810.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGHEEF"
     gene            complement(11363..12358)
                     /locus_tag="VXB91_001368"
     CDS             complement(11363..12358)
                     /locus_tag="VXB91_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV0470811.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHSLLEILDFDWSIFLHDVEKTEK
                     FVFLLLVFSMSITCLLALFWRGIEELSLRKMQANLKRLLAGQEVVQVADPDLDASFKS
                     LSGKLNLLTEALQKAENQSLAQEEEIIEKERKRIARDLHDTVSQELFAAHMILSGISQ
                     QALKLDREKMQIQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFQLGSLDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            complement(12355..13053)
                     /locus_tag="VXB91_001369"
     CDS             complement(12355..13053)
                     /locus_tag="VXB91_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HEV0470812.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAATILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KMVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            complement(13130..14140)
                     /locus_tag="VXB91_001370"
     CDS             complement(13130..14140)
                     /locus_tag="VXB91_001370"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HEV0470813.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSAALKNPTDDS
                     FSVKSSHPNLLLGTNIGLDKPVELGLQTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSEQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKSVGLSRT
                     VLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIADLQKVDYLLYGKLKEAKDQMK
                     KA"
     gene            complement(14124..15131)
                     /locus_tag="VXB91_001371"
     CDS             complement(14124..15131)
                     /locus_tag="VXB91_001371"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HEV0470814.1"
                     /translation="MIAVKTCGKLYWAGEYAILEPGQLALIKDILIYMRAEIAFSDSY
                     RIYSDMFDFAVDLRPNPDYSLIQETIALMGDFLAVRGQNLRPFSLEICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYDVSVDQELLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFDRQKVAAWLEEENLATVLERDWGFSISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLTSSKETVVSFEEALEQGKSEKIIEQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVAKSSGAGGGDCGIALSFDAQSTKTLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            complement(15118..16071)
                     /gene="mvaD"
                     /locus_tag="VXB91_001372"
     CDS             complement(15118..16071)
                     /gene="mvaD"
                     /locus_tag="VXB91_001372"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HEV0470815.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMDFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEYLSEIFGQRYRLIVSKTKDLSQDDCC"
     gene            complement(16053..16931)
                     /gene="mvk"
                     /locus_tag="VXB91_001373"
     CDS             complement(16053..16931)
                     /gene="mvk"
                     /locus_tag="VXB91_001373"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HEV0470816.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVP
                     AESPWRLYEEDTLSMAVYASLEYLDITETCVRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADFLVETTLSHGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            complement(17053..17232)
                     /locus_tag="VXB91_001374"
     CDS             complement(17053..17232)
                     /locus_tag="VXB91_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein"
                     /protein_id="HEV0470817.1"
                     /translation="MLPHDFPLYLMVWSFFRRSMTTGWFQVNGRWYYAYSSGALAVNT
                     TVDGYFVNYNGEWVQ"
BASE COUNT         5390 a         3840 c         3062 g         5226 t
ORIGIN      
        1 aaacattttt agaaatcgat ttgactgtcc tgatcgattt gtcctgttct tgtttcattt
       61 tactatatag atcacattcg aaagaattcg ttccaaaatt gcttggttcg ttcttctctt
      121 ggacgactaa agaattgatg ggcattattt ttttcaacaa ttttcccact gtccataaaa
      181 ataacatgat gggctacatc tctagcaaaa cctatctcat aaagctgatc aaaaactcaa
      241 tctgaggaga aaatccaata agactttcca taataaagga catcctatca agatttttga
      301 acacccgata ggctgccttt ttccgatttt gaagactttt tgtccagctt cttttacctt
      361 ataaataaca acaaaaatca aagacaagct agaaagatta ccgcagataa ctcaaacagt
      421 gttttgaggt tgcagataag actgacggag tcagctcaaa gcactgcttt gaggttgtag
      481 atagaactga cgaagtcagc tcaaaatact gttttgaggt tgcagatgga tgctaacctg
      541 atttgaagag attttcgaaa aagattaaat atactctaca atttgctcaa tcaattcttg
      601 gtcgtctaaa cctgtaactt gtataacaac atctttgact gattgtttag ccaacaattc
      661 acctaatcga atactttctt catcatttac atcgcgatag tcaaaggcat agccaactgt
      721 tttaagtagg tttttatatg acaaactgag ttctttcaat tcacgtatcg gccggatgaa
      781 tcgttcatta tagcctaatt ttcggattgg agtacgagct acgcgactaa cctcgtccac
      841 tatgaaaggg ttttcgaatc gttctataat gactttgtga taattctcca attctttttt
      901 atcaaagttc catttggcaa tcaagagact ccgaatttca gctaatacag attcaatccg
      961 agatttgata ttaggatttt gaagagcttc caaaattgtc ttggcaccat aatgcgcacc
     1021 aatgtaagct gaagttgcat gtccagaatt gactgaaaaa agttttcgct caataaaggg
     1081 ttctaaatct tcttcataat gcacatcttc tagacgtaaa tctggatttt taagacgctt
     1141 ggtttccacg acccattcat taaagggctc gaccataaca aaaagggaat cttcgtgact
     1201 ttgtgttgga acaatcctgt ctactgcagc atttggaaaa cctatgtagt tatcagcaaa
     1261 tgtcaaacct tccggactta aatatttctt gacttcttga taaagaaatt gagacccgcc
     1321 aatcatattt tcacaggcca taacatccaa tgcctgtgta tttcctgcaa ctcggcgagc
     1381 ttcgattcct ttggctagaa gttcagcgat aaaagggagt atattaggtc cgattgcagt
     1441 agtaataata tccgtctttt gaatcgcttc aatgacttgc tcaggatgtt ctttgctatt
     1501 aattccagcc acattagtta cttctatacg agactgtcct ttctgtgcaa tttcaatttc
     1561 atacttgccc ttttcattta gagcatgaat tatctgatta ttgacatcca caaaatcaat
     1621 atggaaatca tttttaaata gaatttcacc tataaaacca cgaccgatat taccggcacc
     1681 aaaatgaaca gaatgtttca ttcaatttct ccttttccta tttgagggac atatatacta
     1741 gatgacaaat gacgaaattc aattattcaa cagcatcaaa taagcgcaat acttcctctt
     1801 ttgactgagc atctgctagt ttaagaacat tatctacatc tgcacagaag atagaaattt
     1861 tctgaataat ttctaagtgt tcattaccaa taccagcaat accaaaaaga accgttgcca
     1921 cttgagggtt agatacattc ccaaaatcaa cccctctagg gacttgaacg actgtaatac
     1981 cagacttgag gacatcattt tttgctgcat ctgttccatg cggtatggcg ataaagttac
     2041 ccatgtaaac agatagctct ttatctcgct caatcatggc ttcaatatag tcttcattaa
     2101 catatccacc ctcataaaga acttgcccac aataacaaat agcttcctcc ttgttagaaa
     2161 attgtttatt aagcttaatc aaatgttttt caagtttcat attagttctc caatttctta
     2221 attttttcgt taaaaatagt atttagcatc tgataaataa tggattgatt tcccgtcttg
     2281 taaatctctg tataaagatg attttcaata atcgactgac tgatagctgt cattaaatct
     2341 ctcgcttcct cgctagcttc tttagacatt agcattagca gacacctttt gacctcttct
     2401 tcctctcgtt tcattgacaa tgcggagata ggtagtttga gttcaaacat agtaaaacta
     2461 tttgttgtta ctttgctaga ctgactatgt aaaagcacca gaccagtatt aggaatagcc
     2521 ataggactat tctggaagtg agataacaat tttcttgtta ggtaatctct gtcactcaca
     2581 ttcttctgat attggatgat ttgttctacc gtgtgctcaa atgattgatt attctccaat
     2641 tgaaccaact cgaattgact caaaagctga ctactagata ttaaataatc ttgcaagtca
     2701 taacttttct ctggagcgat agcatcacgc gcgacaattg tacgatgtgc ctgtacatac
     2761 tgaagtcgtt cctgtaattc aagcaattct ttgacggttg gaaaactaga aattacatcg
     2821 atttcctgat tagtcagcgg cttggtagat aaaatataat catactgact gagatcaata
     2881 ctgtggtaat ctactagaga ctgaatatct atcaactcta caaaaggagc aacactctta
     2941 attttactga ctaataaatc tctagtgacc cgacgttcat ccgttaaaag caaaacacgg
     3001 actggataaa tctctggact acggcctaag ctagagataa aatgtagggc aatcatgcca
     3061 tactcatact ctgtatgaag atatttcgga aaaatatcat tcactaaaag actgatgact
     3121 gtataaagaa atttattcct ttcaactaaa atctggacag attctggcaa attttcaccc
     3181 tgaaaaagga tagggacgcc taaactgagc cgaatatgat ggaaaagaaa attgaataaa
     3241 accttgtcct taaaaaagtc aatcttggta tacatggaaa ccgtatcaat cagatttgaa
     3301 atattgtaga aaaattcacc atcaaatttc tccgtaaaga gcggattgtc ctgacgttta
     3361 atgattaatt catccaagat gctcgcaaaa tagataattt cctgaatact ataaaattgt
     3421 gcagtctgct tagagtaagt ttgaaaaatt ttttgagaaa tttccaaagc ctgcttacta
     3481 gtattaggtg aattttcaat gttttgctcc tgacctataa gagataacaa gatcgcaaaa
     3541 aacatcttca tcctagcatc catatctgga aaacctgaca gttgcttatt aacaatctga
     3601 ctggccagcc tagttctatc tgcttctaaa atatcaaagc tcccaaaatt accggttgaa
     3661 aaatctgcta ctgagataca gtttgtcagt aaaatagcca aaaatcttct cttaccaact
     3721 gaatcaccag aaatccgata acctttttgt cgttcaattt tcagatcaaa gtctaaaaga
     3781 cgcttatcaa tatctgaaat atcctgaata atagttacat tactgacttt cgtgcactct
     3841 tgcaatgctt cattggtgac aaaaccgctc tcagtcagaa ggcgataggt aatcaactct
     3901 tgtctttctt ggggactata ctcaactaac acttcaagtt ctgtcggcaa atcatccaac
     3961 tctccagtca aaatatagta tttcccatgc ttcattattt cgattccata ttgctccatg
     4021 ctatctgtca aatctgataa agttcgataa attgttctag atgaaacctg taagatttca
     4081 gtcatatctt gcattgaaag cttccctaca tgtaggaaag ccttcaataa ttgttcttct
     4141 cgtttggtta atagcattcg taatttagaa acctctagtt ctatttgtac attctagcag
     4201 ccattttgtc atattctggt gttgttacta aactatccac aataagaaat tgagaattcg
     4261 gtgctgcttg ctgcacttct gcctgtaaag aaatagttgt tacaatcatt atgtttttag
     4321 aattaaattc acctaattct gaaattttgg cagtagaaac tggaatacga atattcttgt
     4381 ttctaaagat agcccgaatc gtttcacagc ccatagttgc agttccctgt gctttaccat
     4441 aagcaactac tacagcatca atatggttaa ggtcaatttc ctgactatct actggtgctg
     4501 aagttggtat atctccttca atttctgcta ttggagaagc tcctgttaat gaagctacaa
     4561 tttcatcata acgaggggac gctaagaaat tatcaacaga aacatgaata gcacttggac
     4621 tcttgtcttt agctcttggt gtcagttctt cctgagtaac aattaatgtt tttggtgtat
     4681 caagcaaatt tgagattgcc tgattagata ctggaatctc tagacctgct tttttaacct
     4741 tatctcgaag aatactagct cccatagcag agcttcccat accagcatcg caggcgaaaa
     4801 tgattttttc cactgagtct gtcgaaacaa ctgcatcaac agaagttgat actaactgac
     4861 ctttagactg agccttagct gcttgggtag ccgcctgagc agcttcgagc gaatcctcag
     4921 ttgacttgtc tgcatgaaga ataagggctg ctacaaggaa agaaacaact gctgctacta
     4981 aaacacctag aagaacattt agatggggcc aaacaccttt tggcgccgta gccataatcg
     5041 caataataga acctggtgaa gctggagatt taagaccagc gtctaagagt tgaaaagtaa
     5101 aagttccaga gatacctcct gccatagcag ctaaaaatag agtaggcttc atcataacat
     5161 aaggaaagta aatttcatga atccctccga agaaatgaat aaccattgcc ccccaagaag
     5221 aagatttagc agaaccttta ccgaatacag cataagctaa tagaattccc aggcctggtc
     5281 caggattagc ttccaatagg aagagaattg acttaccagc ttgagctacc tgttctactc
     5341 ccagaggagt aaaaatgcca tgattgaggg cattattgag gaaaaggact ttagccggtt
     5401 cgatgataat attagccata ggaaggaggc gagcattgac aatagcctca acaccattcc
     5461 caacagctcc agtaagagtc gatacgactg gaccgattgc gtagaaagcc aaaagcaata
     5521 atgcaaaacc aacgagacca gctgagaagt tattaactaa catttcaaat ccgggacgaa
     5581 ttttttcttg gaacttctca tcaaatttct tgatagtcca tcctcccagt gggcccatta
     5641 ccatagctcc gataaacata ggaacactag aacctgtgat tgcaccaaca gtagcaatag
     5701 ctcctacaac ggcaccacgt tggccatgga tcatatatcc acctgtgtaa ccaatcagga
     5761 ttggcaataa atacgttaac ataggaccaa caacagtagc taactgttca tttggcagat
     5821 agccatcagc gataaagagg gcagtcaata ctccccaagc aataaatgct ccaatattgg
     5881 gcataaccat atttgaaagc gatgtcccta gtttttgaac cctgactttc aatgatactt
     5941 tttcttccat tagatcatcc tccttttctt aaaactagta tatacaaagt taaaaacctt
     6001 taaaactaaa gttttgtcac agattttgtg tcaaaacatt acttttgacg aggctgggca
     6061 aaaaggctta aaaattataa aacgcatcat atcaggtgta catgaactac accccaaaag
     6121 ttagacagaa aaaatctaac ttttggggtg tttttattat gaaactaact tatgatgata
     6181 aagttcagat ctatgaactt agaaaacaag gatatagctt agagaagctt tcaaataaat
     6241 ttgggataaa caattctaat cttaggtaca tgattaaatt gattgatcgt tacggaatag
     6301 agttcgtcaa aaaagggaaa aatcgttact attctcctga tttaaaacaa gaaatgattc
     6361 ataaagtctg acatgaaggc tagactaaag atagagtttc tcttgaatac ggtctcccaa
     6421 gtcgtacgat acttcttaac tggctagcac aatacaggaa aaacgggtat actattgttg
     6481 agaaaacaag agggagagta cctaaaatgg gacgtaagcc aaaaaagaga cctgaagaga
     6541 ggacagaatt agaacgtctt caagcagaaa atgagtacct gagagcggag aatgccatcc
     6601 taaaaaagtt aagagaactc cgattgaagg aggaaaaaga gaaagacaga aattgtttaa
     6661 gaattaatga ctgagttttc gttagatctt cttctaaaag ccattaaact agctcgttcg
     6721 acctactact atcacttgaa acagctagac aaaacagata aggaccaaga gcttaaagct
     6781 gaaattcaat ccatttttat cgaacacaag ggaaattatg cttatcgtcg aattcattta
     6841 gaactaagaa atcgtggtta tctggtaaat cataaaagaa ttcaaggctt gatgaaagta
     6901 ctcaatttac aagctaaaac gcgacagaaa cgaaaatatt cttctcataa aagacgttgg
     6961 caagaaggca gagaatctca ttcaacgcca atttgaaggc tctaaaacaa tggaaaagtg
     7021 ctacacagat gtgacagaat ttgccattcc agcaagtact caaaagcttt acttatcacc
     7081 agttttagat ggctttaata gcgaaattat cgcctataat ctttcaactt cacccaactt
     7141 agaacaagta caaacaatgt tggaacaggc attcacagag aagcactacg agaatacgat
     7201 tctccatagt gaccaaggct ggcaatacca acacgattct tatcatcggt tcctagagag
     7261 taagggaatt caagcatcca tgtcacgtaa gggaaacagc ccagacaata gtatgatgga
     7321 gtccttcttt gggattctga aatcggaaat gttttacggt tatgagaagt cgtttcagtc
     7381 gcttaagcaa ttggaacaag ccattataga ctatattgat tactacaaca ataaacgaat
     7441 taaggtaaaa ctaaaaggac ttagccctgt gcaatacaga actaaatcct tcggataaat
     7501 taattgtcta actgtttgag ggcagtacag aaaaaccttg atactatgcg ttttttgatt
     7561 gtgaagactt ttatccacct attatacaaa gttaagtatc catcacagtt tacaattagc
     7621 cttcattact taacccattc accattatag tttaagtagt aaccacctac tgtggtatta
     7681 acagctaaag cacctgaatc ataggcatag taccagttac cattgacttg gaaccagcct
     7741 gttttcatat ctccattact tgcatttaga tagtaccaag tcgaaccttc ctgataccaa
     7801 ccagttgcca tagctcctga tgaacggaga tagtaccatt tgttcccaag gttttgccaa
     7861 ccagttttca tatcgccagt ttcagcatct aaatagtacc aagttgaacc atcttgatac
     7921 cagccagttg ccatagctcc tgatgaacgg agatagtacc atttattacc aagatgttgc
     7981 caacctgttt gcatgatgcc agttgctgga tctagatagt accatggagc tgcttttagc
     8041 ttctcttcat cataggtaag agggtaatcc ttaacccaac cacgtgctag ctctccaacc
     8101 gtcaatctgt tgatgcgaga atcaaagcca ccatccttct gcaaataata ccagtcccca
     8161 tcatcataaa cccaaccagt ttttaaagta tgataactac gctgatcttc aaaataatag
     8221 actcgtttct ctgctgggct atcatattct tccccatgat gtttgttggt atttgtagca
     8281 gtttttgctt ctaacacttg cttgccaaca aattcttgta gtaccccatc ttgaccaaag
     8341 taaaaccaat ctggtctaaa agcaatctct tgtcttggag aaggaccaat cgtaaccccc
     8401 ttgtgtggag caggtatata ttgccagccg acaaccatct ctccggataa aggatcaaaa
     8461 taatagtatt tcccatctat cactctccag taggtttctt ttagatcccc ctttttgtag
     8521 taggttctac cattttcttg gacaaactgc catccttcag aatcatctgc aaatactgta
     8581 ctggtcccta gcaaaccgaa gaaaaatgtg gctagtgcga cttgcatcat ttttttcaaa
     8641 agcttcattt tatatatcct ccaacattaa atccactcac cagatgaagc gaagttataa
     8701 actttaccat cgatagtttg gctacctgta accattgctc catttgaatt gagataatac
     8761 cattttccat ttactttttg ccaatctgta agcatcttac cggaactgtc taaataatac
     8821 caagtatcat ttatctcctg ccaacccgtt tgtttatcat gttgtctata atggtaccaa
     8881 ctaccattta ttttcttcca tccttcaaga gagtaacctt taagaaccga ataaataaat
     8941 ggcaaatttc gttcatttaa tttaactgca ctgttaattt gattagctcc atctcctaaa
     9001 gtatgcactc ctactacacg gtgactagca tcataaactg tagatccact agacccctct
     9061 aaagtatcaa cttggtaatc caagaacatg ccatcatcac ttaaaacttg ttttttatct
     9121 gtatacattt gatgaacttt aaaattatat gatggatagc ctgtgatagt cacagttatt
     9181 cctgtcaaat ttttttgact agtaggaaga cccaaagtcc ctaattttgc accaatgggc
     9241 tcttctagaa ttaataaagc caagtcatat tcccttgcat ccttagaatt taaatttcta
     9301 aattccttca aataacgaac ttcctttact ttgatctttc caaatggttc ttgacttgga
     9361 ctaacagccg gaagaacata aatatcatcc gcttctttcc catagtcatg tctgtagtag
     9421 ctgtgagccg ctgtaattaa cacattatct ttaataaaat tcgcacttcc cctcccttct
     9481 acattcattc catcggctac tccataatac ttagataaaa ccatagctga agtcgaatac
     9541 ggatactgta aagtattatc aattttaatc aaatcatcat taccgataat acttctgatt
     9601 gcttttggta gtatgaacca tatgttggtg aaatctcaga taatgaagaa tcattagatc
     9661 ctggaccttt ttctagtgtc tcacttacct catattcttc acccgtacta gaaataacac
     9721 tcaaagcaga tactgtcgat aactggctag ccaataaagt actcgcaata attgaaatac
     9781 ccaatttttt ataaacagtt ttcttcatta ttgtatcctc ctaatgtaat tatagcgtac
     9841 tattctaaat ttcttaatct actatagaat caagaaatct accaccttct ttaaataccc
     9901 tccattatca cataaacagg taaacttttc aattaatgac tgcgcttttc aatcacgcta
     9961 gaggtactta cttgcttctt tgatactaag ttcagccatt ctttccttgt ttttctcaat
    10021 aaagcatgtt acccaagtgg gattcgtttt ggagtagtct cgcagagtcc agccaatggc
    10081 tttattgata aaaaattctg tttggttcaa gttatgaagg agaatctttt ccattaattg
    10141 agtattggtc ttctcttttc ttaacaactg gttgtcaata gcgacacgtc tcagccagat
    10201 attatctgat aggctccatt ttatactcaa tgaaaatcaa agagcaaact aggaagctag
    10261 ccgcagattg ctcaaaacac tgttttgagg ttgcagatag agctgacgtg gtttgaagag
    10321 attttcgaag aatattaaga ttatttcttc tagttcagga tgtttataca ccaaactccc
    10381 tactactcga tctaggatat ctaccgtgtc ccaccaggat tttgtcacga ctaactgctc
    10441 tagcttaggc aaatcggttt cctttagata agactgcatt gctttcaaat agttagcagc
    10501 cacatattgg tattttctag gctccttttc ccagcaagtg tctgcaaaat cccaatcgat
    10561 aatctttgtt tttttcgctt ctggaaaata tttttataga gtttatttct ttcaacctag
    10621 aaaagaaaat tgatggcaca tataggcttc catgggcctt gcttttttag agtcttttgc
    10681 tgcttctagc tcctcaagta aatctgctaa actcatctaa aactcctcat gccccaccaa
    10741 atggtgctga aaggcataga cagccgcctg ggtacgatcg ctaacttcaa gtttggcaag
    10801 aatgttggac acgtgggtct tgaccgtctt gagagagata aagaggtcat ctgcgatgcg
    10861 ctgattttcg tagcccttgg cgatgagttg gagaacatct cgctcacgcg cagtcaattc
    10921 ttcatgaagt tccatatgat tgcggtggta ttcaaccttc ttgctaacct cttgctcaat
    10981 ggccagctcg ccagcagcta ccttactgac ggcatgaagc aattcatctg cactagaagt
    11041 cttgagcata tagcctttgg caccagcatc taagactggc atgatttttt cattgtccaa
    11101 ataagaggtc acaatcaaaa tcttggcttc aggccattct ttaaggattg ctaaggtcgc
    11161 gtcaatccca ttcatctcag gcatgacaat atccatgaca atgacatctg gacgcagttc
    11221 caaggccaag tcaatccctt gagacccgtt ggacgcctca cccacaactt ctacatcgtc
    11281 ttggaggtca aagtagcttt tcaagcccaa tcggaccatt tcatggtcat ctactagtaa
    11341 aattttcatc tttactcctt tatcattcct tatctaacag gggaatacgg atatcaaccg
    11401 ccagcccttg cttgggagct gtcaagagtt gaactgttcc agccatatct tcaacccgct
    11461 ccttgatatt tcgcagtcca taactcaagt cgtctaagct ccctaactgg aaaccaatcc
    11521 cattgtccac caccttcagt tgcaattcaa catctgtctg atagaggtag acatctaggc
    11581 aagatgcctg ggcatggcgg agggtattgc taatcaactc ttgcaggata cggaagatat
    11641 gctcctcgat tttcttaggc aatttcgtca tattctgctt gagactaacc ctaagatcac
    11701 tcttgtcctc aagctctttt aagagaatct gaatcccttc tatcaagctc ttctgctcca
    11761 gttcaactgg tcgcaaatgc aagagcaaaa cccgcaaatc cttctgggct gtttctaaaa
    11821 tagctgtgac actctgcaac tggatctgca tcttttctct atccaatttc aaagcctgct
    11881 gactgatacc cgataaaatc atgtgggccg caaacaactc ctgactgact gtatcgtgca
    11941 aatcccgagc aattcgcttc cgttccttct cgatgatttc ctcttcctga gcaaggctct
    12001 gattttcagc tttttgaaga gcttctgtca aaaggttaag tttacctgat aaggacttga
    12061 aactggcatc caaatctgga tctgcaacct gaaccacttc ttgccctgcc aataaacgct
    12121 tgagattagc ctgcattttt cttagagaaa gctcttcgat ccctcgccaa aacagggcta
    12181 agagacaggt tatggacatg ctgaaaacca acaataaaaa gacaaatttt tctgtttttt
    12241 cgacatcgtg caaaaagata gaccagtcaa aatcaagtat ttccagcaag ctgtgggaga
    12301 aaaaaaagac aaacaggaag gaggtgagag caataatgac ataggcttgt tttttcatcc
    12361 tctaaccacc tccacatcac caatcatagt ggtcaagaaa atcttgacac tcttgttact
    12421 cttgagatag tcttttgttt cttgatgata gtgttcattg cggagggctc gcttgggctg
    12481 gttgaaaaaa gtcaaatccc catagagaca gttaacgctg agactgactt ccacatctac
    12541 aggtacgatg attttggtcg ttcctaccat ctttctgagg ataatgacat tgtcatgatt
    12601 ggttaagatg accctctcca gatgaatagt gtccttgccc atgaagcgaa agagattgat
    12661 atcatcgaat tggcaagtct ggtagcttga aaaatgatga agatttccaa accaacgatt
    12721 tttctccttc ttaaccgtca cgacctcttc aaaaaccaaa ttggtctgct ctttttcctg
    12781 gttcatcatc gggtaaagaa gaaagaggct atagataacc gcaacaaaaa tagctagaat
    12841 cacaaaagga ttgagcataa cgatgaaaaa gaagagaatg gttgccgcta ctaaaagaag
    12901 attatttccc tctttaccag tgtagtagcg aatcaaaagc aaaaagagga atagtatcag
    12961 cagaaaacgc gaaaaatgct ctgataccat caaaatcaga gctcctgtca gaagacaggc
    13021 ttcgataaat aaaaagattt taaattttct cataggttca tcctctccct tctattttat
    13081 cacaattcaa aaaagtcacc tcagtctgag gatggaaaaa aggcgctggt tacgcctttt
    13141 tcatctgatc ctttgcttct tttaattttc cataaagaag atagtctact ttttgtagat
    13201 ctgctatggt ggcacagtta agggaacaca taatcaagcg taggtctgct ttccagcctt
    13261 ggacaatgcc aatcacttct tcaactgtgt aggtttcaac caattccaga acggttcgtg
    13321 acaatcccac agacttagca ccaaaaacca agcacttaat catatccagc ggattccgaa
    13381 cccctccact aaccaagagt tcgaccttat ctttccattc ttgggcattg agaagggcct
    13441 gcatggtaga ctgaccccat tgattgaggt aatcacgctg gccactacga cggttttcga
    13501 tataggcaaa gctggtgcca ccacgacccg ataggtccac tgtacgaaca ccgaattcat
    13561 aggctctttc gattgtcttg gcatccattc caaagcccac ttccttgagg acaataggaa
    13621 cgggaatttg ctcgctataa tctgctagat gcgattgcca gcttctaaac ttcctttctc
    13681 cctcgggcat gagtaattcc tgcatgacat tgacatgcac ttgcaataga acaggattca
    13741 tctcttctac agtctgaagt cctaactcga caggcttgtc caatccaata ttggttccaa
    13801 ggaggagatt gggatgacta gacttgacag aaaaagaatc atccgttgga tttttgaggg
    13861 ctgcgctata agaacccgtt acaaataaaa taccacagga ttccgccacc tgagccagct
    13921 tttgattgat ttctcttccc ttattacttc caccagtcat ggcattgata taaaaaggaa
    13981 agtcccactt tcgaccagca aactctgtcg aaagatcgat ttcatccaga ttgtaaagag
    14041 gcaaggaaga atgaatcagc tccacctcat caaagctatt ataggaactt ttctgctcaa
    14101 gggcatagag gatatgctcg tccttacgat ttgtcgtcat gtcctatcct ttcttgatat
    14161 aagagctcaa tccccagatc ggcccaacga ttttttaagg ttttggttga ttgcgcatca
    14221 aaactcaggg cgatgccaca gtcaccacca ccagcaccac tactcttggc aacggcctgc
    14281 aaatcttgac tggcttcttt caactgtcta agcaaaggcg tgtaaatatc tgtactcaag
    14341 ccttctaaaa gcttgctggc tacttctact tgctcgataa tcttttctga tttcccctgt
    14401 tccaaggctt cctcaaaaga aaccaccgtt tcttttgagg aagttaaaaa attttgattg
    14461 atattttgct tgatttgctg gaccatgtga ctcgatacag ccacttcctt ggtccatccc
    14521 actaagaaat cacattctaa agttggtttc acttgtgaaa ttgaaaagcc ccaatcacgc
    14581 tccagaactg tcgccaagtt ttcttcttct aaccaagcag ccaccttctg gcgatcaaat
    14641 gactggtaga gaaccaaatc ctctgccaca atacaggcaa ggtcgcccat ggaaccattg
    14701 tctcctcgct tgagcaagac agcgctagtc agcttgaaca agagctcctg atcaacagaa
    14761 acatcataca gagccagtaa agccttgaca accaagacaa cgacgctgcc actagaacct
    14821 agaccaaact ttttcccttc tcgttccatt ttgccacaga tttctagaga aaaaggtctt
    14881 aaattctgac cacgaacagc gaggaagtct cccatcaaag caatcgtttc ttgaatcaag
    14941 ctgtagtcag gattaggcct taagtccact gcgaaatcaa acatatctga atagatacgg
    15001 tagctgtcag aaaaagcaat ctcagccctc atatagatga gaatatcctt tatcaaagct
    15061 aactgccctg gctctaaaat agcatattca cctgcccaat agagttttcc gcaagtttta
    15121 acagcaatca tcttgactca aatcctttgt ttttgacaca atcaagcgat aacgctgacc
    15181 gaaaatttct gacaaatact ccaagtcttt ctcctgacag aagaccttaa cattgggacc
    15241 agcatccatg gtaaagtagc aggcctctcc tttctcacga agctggcgaa caaagtccat
    15301 agcctcataa gaggcatccg tcagataaga aaaggctgga ctagcagtct ttgtcgtagc
    15361 atgcatagcc agggcatttt tctccgttaa ttctccaatc ttggcaaaat cattttcctt
    15421 gagataaatc agcatatcct gatagtcctt ctcagactga cgaacccagt cgtcgaaagt
    15481 cgtcgaggtt tccacacaaa gtttcatccc gtcacggcta gagattggtt ttttcttgtc
    15541 ctctagcacc aacataatca tagctagttt caagtctgtc tctacagggt aaatttctcc
    15601 actatcctta tcccaggctc ctagtggtcc ataaaaactc cgagaagaag agcctgaggc
    15661 aaatttggct tcctgtgcca actgacttct atccaatcca agcttgaaat aagcattaca
    15721 agccttgacc agggcggaca aaccactaga acttgaggac aggcccgctg ccgtaggcat
    15781 attgttttga gtatcgatac ggacaaagcc ctcaccagct ggacgataac ggtcaataat
    15841 cttactcatc ttggcatgct cgacctcatt ttgtagctga ccattgatgt aaaattcgtc
    15901 agctgttaca ttggctggta aaggcgacaa ggtcgtctct gtatacatat tttccaaagt
    15961 tagagaaata ctgctagtag caggcaccat ctctttttct tttttctttc cccaatattt
    16021 gataatagca atatttgcgt aggaacgtac tgttacaggc tctctatcca tgtctgaaca
    16081 gctcctttct cttctaatct ttctgctagt tcttgtgcgt gtgtcaaatt ggttaccaag
    16141 gctatgatac aacctcctag cccaccaccg ctcatcttgg cacccagagc accatggcta
    16201 agagtcgttt caaccaaaaa gtctgcctca gggctactga ctccaatttc ttttaaatgt
    16261 aaatgcgctt gactgaggat ttgtcccagt ccttcagcat ctttttgtga aatcgcaact
    16321 tctgcttgct gggttaattc tcccaaggca tgcaaaaacg gtagggcatc cttgccctta
    16381 ttttgaacca cttggatggc ttcacgagta tgaccataaa cacccgtatc ggcaatcacc
    16441 aaataggcgg ataaatccat ctcaagttct gtaaatccta cgttcttgat aaagcgaata
    16501 ggttggtcac tgagacaggt cttagcatcc aaaccactag gattcatatg agcaatcatc
    16561 tcagctcgat tgaccaagat ttctagtaca tcatgaggca gatcagcctg atagtagtca
    16621 aataccgcac gaatggccgc tatgctgata gccgctgacg aacccatccc ccgtttctca
    16681 gggatagccg agtcaatctc acaacgaacg caggtttctg tgatatccaa atactccagt
    16741 gaagcataaa ccgccatgga caaggtatcc tcctcataaa ggcgccaagg actctctgca
    16801 ggaactacct tacaggtcac ctccacctcc aaaagaggca gggaaatggc aggataaccg
    16861 taaacgaccg catgttcccc tattaaaatt atcttactat gtgcctgacc gacaccaact
    16921 ttttttgtca ttttttcctt ttactagacg aaaaaacgtc ttatttttca tacaagtatt
    16981 aattctttcc tatctatttt attatatttt cacaaaaaaa gcgattgttt ccattcacaa
    17041 tcgcttcttt cattattgaa cccattcgcc attataattg acaaaatagc catctacggt
    17101 cgtattcact gccaaggcac ctgagctata agcgtagtac catctgccat tgacctggaa
    17161 ccaacctgtc gtcatagaac gacgaaagaa actccatacc attaagtaaa gaggaaagtc
    17221 gtgagggagc atgcgccatt gacaacctgt tttagtgacg tacaaagtct cattaacaag
    17281 tactcgtttc ggtcatttat aggtgcggtg tttggagaaa tagggttcaa tcttagccca
    17341 ttcttgatcg tttaaatcag tatcatatac tttgcgtgtc ataactctag tttaacattt
    17401 tttgtgaata caggttctaa ataatcgacc acgaaaattt cttaagtgga aaacgcctta
    17461 tgaagtatgc tacgggaaag ttatgcactt aatttgacaa ttcaagatgt aaaaatat
//
LOCUS       DAVLBE010000036        17005 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.036, whole genome shotgun sequence.
ACCESSION   DAVLBE010000036 DAVLBE010000000
VERSION     DAVLBE010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17005)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17005)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17005
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.036"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            333..1379
                     /gene="pheS"
                     /locus_tag="VXB91_001375"
     CDS             333..1379
                     /gene="pheS"
                     /locus_tag="VXB91_001375"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HEV0470818.1"
                     /translation="MSTIEEQLKALREETLTSLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
     gene            1379..1888
                     /locus_tag="VXB91_001376"
     CDS             1379..1888
                     /locus_tag="VXB91_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0470819.1"
                     /translation="MIRKVEMADVEVLAKIAKQAFRETFAYDNTEEQLQEYFEEAYSL
                     KTLSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GLGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            1965..4367
                     /locus_tag="VXB91_001377"
     CDS             1965..4367
                     /locus_tag="VXB91_001377"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HEV0470820.1"
                     /translation="MLISYKWLKELVDIDVPSQELAEKMSTTGIEVEGVESPAAGLSK
                     IVVGEVLSCEDVPETHLHVCQVNVGEEERQIVCGAPNVRAGIKVMVALPGARIADNYK
                     IKKGKIRGLESLGMICSLGELGISDSVVPKEFADGIQILPEDAVPGEEVFSYLDLDDE
                     IIELSITPNRADALSMCGVAHEVAAIYDKAVNFKEFTLTETNEAAADALSVSIETDKA
                     PYYAARILDNVTIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDNF
                     EGTDIRVREARAGEKLVTLDGEERDLDVNDLVITVADKPVALAGVMGGQATEISEKSS
                     RVVLEAAVFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAAASLIAELAGAT
                     VRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFTV
                     RVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKDDGTAGELTATQKLRRQVRTIAEG
                     AGLTEIITYTLTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNVA
                     RKNKNLALYEIGKVFEQTGNPKEELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYAK
                     GILEALFTRLGLQVTYTATSEIASLHPGRTAVISFGDQVLGFLGQVHPVTAKAYDIPE
                     TYVAELNLSAIEAALQPATPFVEITKFPAVSRDVALLLKAEVTHQEVVDAIQAAGVKR
                     LTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQASLEEKVNAE
                     VR"
     gene            complement(4435..5436)
                     /locus_tag="VXB91_001378"
     CDS             complement(4435..5436)
                     /locus_tag="VXB91_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEV0470821.1"
                     /translation="MIKTFLSALSVILFSIPIITYSFFPSSNLNIWLSTQPILAQIYA
                     FPLATATMAAILSFVFFSLSFYKKNKQIRFYSGILLLLSLILLLFGTDKTLSSASNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQVGL
                     SMANYDIFTSPPTNSGIAPVTVIVKKSYGFYTEAKTFHTTRFGTIVLHSRKQNIPDII
                     ALHTAPPLPGLMEIWKQDLNIIHNQLASKYPKAIIAGDFNATMRHGALAKISSHRDAL
                     NVLPPFERGTWNSQSPKLFNATIDHILLPKNHYYVKDLDIVSFQNSDHRCIFTEITF"
     gene            5592..6038
                     /locus_tag="VXB91_001379"
                     /pseudo
     CDS             5592..6038
                     /locus_tag="VXB91_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            6164..6430
                     /locus_tag="VXB91_001380"
     CDS             6164..6430
                     /locus_tag="VXB91_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0470822.1"
                     /translation="MEGCPSELFSKEEILESDMRVAIMSELIEARYEQGISQKKLEEV
                     SGISQPVIARMETGESSLQLDTVLKVLTSLGKTLAVVPLEQGKS"
     gene            6691..8940
                     /gene="metE"
                     /locus_tag="VXB91_001381"
     CDS             6691..8940
                     /gene="metE"
                     /locus_tag="VXB91_001381"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HEV0470823.1"
                     /translation="MSTTIIGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDATFLFNVVPASVQNLDLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSLVVAYQEVFAKLAELGATRIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLLQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYVGIVNGKNIWRNNYEKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFATERVGENAELRARIAG
                     LTDADYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNSITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRRDWYEDYLDWAIPAFRLVH
                     STVAPDTQIHTHMCYSEFTDIIPAIDNMDADVISFEASRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            9004..9870
                     /gene="metF"
                     /locus_tag="VXB91_001382"
     CDS             9004..9870
                     /gene="metF"
                     /locus_tag="VXB91_001382"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HEV0470824.1"
                     /translation="MSRQTPSLSFEVFPPNPAVGNGNIISALQDMQELAPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            10555..12768
                     /gene="pnp"
                     /locus_tag="VXB91_001383"
     CDS             10555..12768
                     /gene="pnp"
                     /locus_tag="VXB91_001383"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HEV0470825.1"
                     /translation="MAKQVFQTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDGQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELIAFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQVVKDQVT
                     AVYEEKYADHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDLEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRPELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHQKDHKPKKEFTETPKDSE"
     gene            12784..13401
                     /gene="cysE"
                     /locus_tag="VXB91_001384"
     CDS             12784..13401
                     /gene="cysE"
                     /locus_tag="VXB91_001384"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HEV0470826.1"
                     /translation="MGWWRETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFLW
                     KHGFKLLARMYSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHEVEEKREYYVNKLEQAKDASHRSSGL"
     gene            13413..14297
                     /locus_tag="VXB91_001385"
     CDS             13413..14297
                     /locus_tag="VXB91_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0470827.1"
                     /translation="MIQARNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGKLVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFERETASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYPLANVSHLEVLLADSSY
                     QDQISQLKFQAFSEEHESREVVDRYVAEALKDPESRLYILLKDGQVIGTCTVDLSTNT
                     NYFYGLAISEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            14384..15727
                     /locus_tag="VXB91_001386"
     CDS             14384..15727
                     /locus_tag="VXB91_001386"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HEV0470828.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYKVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGMKPATRHPRVVEFMADIIRFVEDLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLELGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMAKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFETADQIRDQLVTQGIKLLDTKDGVRWTRD"
     gene            15720..16106
                     /locus_tag="VXB91_001387"
     CDS             15720..16106
                     /locus_tag="VXB91_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HEV0470829.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLIALMLEEQILTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            16110..16994
                     /locus_tag="VXB91_001388"
     CDS             16110..16994
                     /locus_tag="VXB91_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HEV0470830.1"
                     /translation="MRAKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLTSW
                     LDMMRTLFPNCQTVLQVGAQDYVFVLQQDKYTSVRDILSDTIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
BASE COUNT         5051 a         3320 c         3891 g         4743 t
ORIGIN      
        1 tttcatctta tttcaatccg ctataaagtt agataagaat aagctaacaa gcagaagtaa
       61 gataggtctt gcaagaatgg taaaaatctg ataaactaag tggtaattga atagaaatct
      121 gaaagactag tagcccaagg gaagtatatc agggaggaga gccgtgactg caagctctct
      181 atatgaaagc tgggtgaatt cacttgcgca tggatttaga aatgaaggtc tgacttgtca
      241 gatgaaaacg gatggtaccg cgtgtcaacg ctccgagtgg agtttttggc atgtggtttt
      301 ctttttatct acgagagact gatggaggaa atatgtcaac tattgaagaa caattaaaag
      361 cgcttcgcga agaaacgctg actagcttga agcagattac tgctggaaat gaaaaagaga
      421 tgcaagattt gcgtgtctct gtccttggta aaaagggttc gctcactgaa atcctcaaag
      481 ggatgaaaga tgtttctgct gagatgcgtc caatcatcgg gaaacacgtc aatgaagctc
      541 gtgatgtctt gacagctgct tttgaagaaa cagctaagct cttggaagaa aagaaagtcg
      601 cggctcaact ggctagcgag agtatcgatg tgacgcttcc aggtcgtcca gttgcgactg
      661 gtcaccgtca cgttttgaca caaaccagtg aagaaatcga agatatcttc atcggtatgg
      721 gttatcaagt cgtggatggt tttgaagtgg agcaagacta ctataacttt gaacgtatga
      781 accttccaaa agaccaccca gctcgtgata tgcaggatac tttctatatc actgaagaaa
      841 tcttgctccg tacccacacg tctccagttc aggcgcgtgc tatggatgcc catgattttt
      901 ctaaaggtcc tttgaagatg atctcgccag ggcgtgtctt ccgtcgcgat acggacgatg
      961 cgacccacag tcaccaattc caccaaatcg aaggcttggt agttgggaaa aatatctcta
     1021 tggctgatct tcaaggaacg cttcagttga ttgtccaaaa aatgtttggt gaagagcgtc
     1081 aaattcgttt gcgtccatct tacttcccat tcacagagcc atctgttgag gtggatgttt
     1141 cttgcttcaa gtgtggtgga gaaggctgta acgtatgtaa gaaaacaggt tggatcgaaa
     1201 ttatgggagc cggtatggtt cacccacgtg tccttgaaat gagtggtatc gatgcgactg
     1261 tatactctgg ttttgccttt ggtcttggac aagagcgtgt agctatgctc cgttatggaa
     1321 tcaacgatat ccgtggattc taccaaggag atgtccgctt ctcagaacag tttaaataat
     1381 gattagaaaa gtagaaatgg cagatgttga ggtgttggct aaaattgcca aacaagcctt
     1441 tcgtgaaacc tttgcgtatg ataatacgga agagcagtta caggaatact ttgaagaggc
     1501 ttatagtctg aaaactttgt caactgagtt gggaaatcct gactctgaaa cctatttcat
     1561 tatgcatgag gaggagatag ctggttttct caaagtcaac tggggaagtg ctcaaactga
     1621 gagagaatta gaggacgctt ttgaaattca acgcctctat gtgctacaaa aattccaagg
     1681 atttggacta ggtaagcaac tgtttgaatt cgcacttgaa cttgctacaa aaaatagttt
     1741 ttcttgggct tggctaggtg tttgggagca taatacaaaa gctcaagcgt tttataatcg
     1801 atatggtttt gaaaaattta gccaacatca ttttatggtt ggtcaaaaag tagatacgga
     1861 ttggttactg agaaagaaat taaggtaaga agaggattct tctattgaaa tgataggaaa
     1921 ggaaaagaac cagtgtggca atggtcattc tggagaacta aattatgctt atatcttata
     1981 aatggttaaa agaattggtg gacattgatg tgccatcaca agagttggct gaaaaaatgt
     2041 caactacagg aatcgaggta gagggtgtcg aatcaccagc tgctggtctc tcaaaaattg
     2101 tcgtcggtga ggtcttgtct tgcgaagatg tgccagagac tcacctccat gtttgtcagg
     2161 ttaacgttgg cgaagaagag cgtcagatcg tttgtggtgc cccaaatgtg cgtgctggga
     2221 tcaaggtcat ggtggctctt ccaggagctc gtatcgctga taactacaaa atcaaaaaag
     2281 gaaaaatccg tggtttggag tcacttggaa tgatctgttc acttggtgaa ttgggaattt
     2341 ctgactcagt tgtgcctaag gaattcgcag atggcatcca aatcttgcct gaagatgccg
     2401 tgccaggtga ggaagtcttt tcttacctag acttggatga tgaaatcatc gaactttcca
     2461 tcacaccaaa ccgtgcagat gccctttcta tgtgtggagt ggctcacgaa gtggcagcca
     2521 tctatgacaa ggcagtcaac tttaaagaat ttactctaac agaaactaat gaagctgcgg
     2581 cagatgccct ttctgtcagc attgagacag acaaggcgcc ttactatgca gctcgtatct
     2641 tggacaatgt gaccatcgca ccaagtccac aatggttgca aaatcttctc atgaacgaag
     2701 gaatccgtcc catcaataac gtagtggacg tgaccaacta catcctgctc tattttggtc
     2761 aaccaatgca tgcctttgac ttggataact ttgaagggac tgacatccgt gtgcgtgaag
     2821 cgcgtgctgg tgaaaaattg gtgaccttgg acggtgaaga acgtgacttg gacgtgaatg
     2881 acctagtcat cactgtcgca gacaagccag tagcccttgc aggtgtcatg ggtggtcaag
     2941 caacagaaat ctctgaaaaa tctagtcgtg ttgtccttga agctgctgtt ttcaatggca
     3001 aatctatccg taagacaagt ggtcgcctga accttcgttc tgagtcatct tctcgctttg
     3061 aaaaaggaat taatgtggca acagttaatg aagcccttga tgcggcagct agcctgattg
     3121 cggaacttgc aggtgcgacg gtgcgtaagg gcatcgtttc agcgggtgag cttgatactt
     3181 cagatgtaga agtttcttca acccttgctg atgttaatcg tgtcctcgga actgagctgt
     3241 cttatgctga tgtagaagac gtcttccgtc gtcttggctt tggtctttct ggaaatgcag
     3301 acagctttac agtcagagtc ccacgtcgtc gttgggatat cacaatcgaa gctgacctct
     3361 ttgaagaaat tgctcgtatc tatggttatg accgcttgcc aactagtcta ccaaaagacg
     3421 atggtacagc aggtgaattg acagccacac aaaaactccg ccgtcaagtt cgtactattg
     3481 ctgaaggagc aggtttgaca gaaatcatca cctatactct aacaactcct gaaaaagcag
     3541 ttgagtttac ggctcaacca agtaacctta cggaactcat gtggccaatg actgtggatc
     3601 gttcagtcct ccgtcaaaat atgatttcag gtatccttga taccgttgcc tacaacgtgg
     3661 ctcgtaagaa taaaaacttg gccctttacg agattggaaa agtctttgaa caaacaggta
     3721 atccaaaaga agaacttcca aatgaaatca acagttttgc ctttgccttg acaggcttgg
     3781 ttgctgaaaa agatttccaa acagcagcag ttccagttga tttcttctat gctaagggaa
     3841 tccttgaagc cctatttact cgtttgggac tccaagtaac ctatacagca acatctgaaa
     3901 tcgctagcct tcatccaggt cgtacagccg tgatttcatt cggtgaccaa gttcttggtt
     3961 tccttggcca agtgcatcca gtcactgcca aggcttacga tattccagaa acgtatgtgg
     4021 ctgagcttaa cctttcagct atcgaagctg cgcttcagcc agcgactcca tttgtagaaa
     4081 tcaccaaatt cccggcagtc agccgtgacg ttgcccttct cctcaaggca gaagtgactc
     4141 atcaagaagt tgtagatgct atccaagctg ccggcgtgaa acgtttgaca gatatcaaac
     4201 tctttgacgt cttctcaggt gagaaattgg gacttggtat gaagtcaatg gcttatagct
     4261 tgaccttcca aaatccagaa gatagcttaa cggacgaaga agtcgcacgc tatatggaaa
     4321 aaatccaagc atcgctcgaa gaaaaagtca atgcagaagt gcgttaaacg atagtatgat
     4381 acaaattccc cctctagttt atgaacacta gaggggtgat tttatataaa ataattaaaa
     4441 tgtgatttct gtaaaaatac atctatgatc agagttttga aaacttacaa tgtctaaatc
     4501 tttaacatag tagtggtttt taggcaataa aatatgatct attgttgcat taaaaagttt
     4561 tggactttgg ctattccaag ttcctctttc aaaaggtggc agtacattta atgcgtccct
     4621 atgagagctt atttttgcaa gtgctccatg acgcatagtt gcattaaaat cacctgcaat
     4681 aatagccttt ggatattttg aagccaattg attatgaatg atgtttaagt cttgcttcca
     4741 gatttccatt aaacctggca gaggaggagc agtatgcaag gcaatgatat ctggtatatt
     4801 ttgttttctc gaatgtaata caattgtccc gaaccgtgtt gtatgaaaag ttttagcttc
     4861 tgtatagaaa ccataacttt tcttgacaat cacagtcaca ggagctattc cactattggt
     4921 aggtggagaa gtgaaaatat catagttggc catagaaagt ccaacttgat gaaacaatag
     4981 tttgattctc tggttttctt gctcacctct gatattggta gctagttcag ggaatatagc
     5041 catatcggcg tcaaaatggc taaaaattcg ctcaatatgt tgtgcttcta tttgattagc
     5101 gacgttccaa gttactaatt ttaaggtttt agtcttattt gatgcagaag aaagggtttt
     5161 atctgttccg aataatagta atatgagcga tagtaagagc aaaatgccag agtaaaaccg
     5221 tatttgttta tttttcttgt aaaaagatag ggaaaaaaat acgaaactta aaatagcagc
     5281 catagttgca gtagctaagg ggaaggcata aatctgtgcc aagataggtt gggtagatag
     5341 ccaaatgtta agattagaag atgggaaaaa agaataagtt ataataggga tagaaaagag
     5401 aatgaccgaa agggcagaga gaaatgtttt aatcattgtg tgagtacctc aatttgcaat
     5461 ggttgctcgg agctaatgtg actttgtgac tttacttgat tgatattctt tttcttgtct
     5521 tcctcataga ttaagtacaa cccaagtaaa aaaagtccaa tttaagattg aaatgattaa
     5581 aaggcacaga aatgcaagac aattatacta caaaaggcaa acatttgaca atcgatagcc
     5641 gtcgcttaat cgaacgatgg aaaaaagaag gaaaatcaaa tagagaaatt gcctctctac
     5701 ttggaaaagc tcctcaaact atccatactg aaatcaagta tgggacagtc cgacaatgtc
     5761 ttggaaaagg gcgcttcaaa gagatttatt ctgccgacta cgctcaacag tcttatgaaa
     5821 ataatcgcaa gcactcggtc aagaaatcaa gcttgactaa gaaactaaag gaaaagattc
     5881 tccactatca taaccaaaaa ttttcgcctg aaatgatggt gatggctaaa ggggttaacg
     5941 tgggaatttc aaccatttac tattggattc atcgtggaaa attggggtta agcaagcagg
     6001 atctgcttta tcctagaaaa ggaaaagcgc ttaagaaata ggctagcacc aactttaaac
     6061 ccgctggtca atctatcgaa tcataattcg ctcatttttt taaaaataca tagacgtaaa
     6121 aaaaagaggg ttaagtgatg aagaatagtg ctattgggag taattggaag gatgtccatc
     6181 tgagctcttt agcaaggagg aaatccttga aagtgatatg cgagtggcta tcatgagcga
     6241 gttgattgag gctaggtatg aacaaggaat cagtcagaaa aagctggaag aagtcagtgg
     6301 aataagccag cctgtcatag ctaggatgga gacaggagag agcagtcttc agttggatac
     6361 ggtcttaaaa gttctaacca gtctaggaaa gacactagca gtcgttccac ttgaacaggg
     6421 gaaaagttga ctagaatcag ttatagtctt ttctaataac aggtcatagt cacttataag
     6481 aattactaat aacatgtttt agtattctaa ttggaatata gctgtaaagt aagaattaca
     6541 aaggatttga gacgtttgct tcaagtcttt ttcttttgtc cgaaacagat atatagtttc
     6601 aaactatatc aaaccctaat tttttacaat tatacagacg ctttcttttc tgttaagata
     6661 gtttcaacaa caaattttgg aggacacatc atgtcaacta caatcatcgg tttccctcgt
     6721 ttgggcgaat tccgtgaatt aaaatttaca actgaaaaat actttagaaa agaaatctca
     6781 gaagaagaac ttttagcagc agcaaaagac ttgcgtgcta aacactggaa cattgtcaaa
     6841 gaaaaaggca tcactgaaat tccatcaaat gacttttctc actatgataa cttcctagat
     6901 gcgactttcc ttttcaacgt ggtgcctgca tccgttcaaa acttggactt gtctgacctt
     6961 gagcgctact tcgctttggg acgtggttac cagggagaaa aaggggacgt tcgcgccctt
     7021 ccaatgaaga aatggttcaa cactaactac cactacatcg ttcctaaatt tgaaaaagac
     7081 actcaagtaa aattggctgg tcacaagatt ttcgatgagt tccaagaagc aaaagaactt
     7141 ggattgaaca ctcgtcctgt tcttgtaggt ccattcactt tccttcaatt gtcagacttt
     7201 gaagaaggcg tgaaagcaga cgacttcgta gatagcttag tggttgctta ccaagaagtt
     7261 tttgctaaat tggctgaact tggtgcgact cgcatccaat tggatgaagc ggctcttgta
     7321 aaagacttga cagctgaaga aaaagctctc ttcttgaacc tttacaacaa actcttggct
     7381 gacaaaaaag gtcttgaagt cttgcttcaa acttatttcg gtgatgttcg tgacgtatac
     7441 gctgaccttg taaacttgcc agtagatgct atcggtcttg actttgttga aggtaagaaa
     7501 actcttgaac tcgttaaagg tggcttccca gctgacaaga ctctctatgt aggtattgtc
     7561 aatggtaaaa acatctggcg caacaactac gaaaagagct tggctgttct tgagcaaatc
     7621 ccagctgaaa acatcgtttt gacaagctct tgctcacttc ttcatgtgcc atttacaact
     7681 gctaatgaag aatttgaacc agcactcttg aaccactttg cctttgcagt tgaaaaattg
     7741 gatgaaatcc gtgacttgga tgctatccgc aatggtcaag gttcagaagc tcttgcagcc
     7801 aacaaagaac tctttgcgac tgagcgtgtt ggtgaaaatg ctgaacttcg tgcgcgtatc
     7861 gctggcttga cagacgcaga ctacactcgt ttgccagcct ttgcagaacg tgaagctatc
     7921 caagaagaag ctttcaaact tccagctctt ccaacaacaa cgattggttc attccctcaa
     7981 acaaaagaag ttcgtgccaa acgtttggct taccgtaaag gtgaattgtc tcaaaaagag
     8041 tacgatgctt tccttgctga aacgattgac gaatggatca agtggcaaga agatattgac
     8101 tttgatgtcc ttgttcacgg tgaatttgag cgtaatgaca tggttgagta cttcggtcaa
     8161 aacttgtcag gatacctctt ctctaaaaat ggatgggtac aatcatacgg tatgcgtggg
     8221 gtaaaaccac caatcatctg gggtgatgtc actcgtctta actctatcac tgttaaatgg
     8281 tctagctatg cacaaagtcg tacaaacaaa cctgttaaag gtatgttgac tggacctgtt
     8341 accatcctta actggtcatt cccacgtgaa gacatctcta tcaaggattc aactcttcaa
     8401 atcgcccttg ctatcaagga tgaagtactt gaccttgaag ctgctggtgt gaaaatcatc
     8461 caaatcgacg aggctgctct tcgtgaaaaa ttgccactcc gccgtaggga ctggtacgaa
     8521 gactaccttg actgggctat tcctgccttc cgcttggtac actcaacagt agcgccagac
     8581 acacaaatcc acactcacat gtgttactca gaatttacag atatcatccc agctatcgat
     8641 aacatggatg cagacgttat ttcctttgaa gctagccgtt caaaccttga aatcttggac
     8701 gaactcaaag cgaaaaactt ccaaacagaa gtgggacctg gggtttacga tatccactca
     8761 cctcgtgtac caaatgaagg cgaaatcgac aacacaatcg aagccatcct tgctaaagtg
     8821 ccaagcaaga aagtttggat caaccctgac tgtggtttga aaacacgtgg tatcccagaa
     8881 acaaaagaaa gcttgatccg ccttgttgaa gcagctaaag ctgcgcgtga gaaattgtaa
     8941 gattggattt ctctccatac agtggttgtt caaaaagaaa tcaactagaa aaggttatta
     9001 catatgtcac gccaaacacc gtcactctca tttgaagtgt tccctccaaa cccagccgtg
     9061 ggtaatggta acattatttc agccttgcag gatatgcagg agttggctcc ccattttatc
     9121 agtgtaactg ccagcaataa taaatttaat atcaaggaaa cgacggttcg tttggctgac
     9181 tttatccaaa atgacttggc gattccgacc attgcccact tgccagctat ttatctaact
     9241 aaggacaagg ttgctgaaac tattgctgac ttggacaaag ttggggtgca gaaaatcttg
     9301 gctcttcgtg gggatattat tccagacgta gaaccacaaa aggatttccg ctatgcaacc
     9361 gacttgattg agtttatcaa ggaacaagcc cctcactttg atattattgg agcttgctat
     9421 ccagaagggc atccagattc gccaaatcag atttcagata ttcaaaatct taagaagaaa
     9481 gtggatgcag gctgttcgag cctcgtaact cagctcttct ttgataatga gcgcttctat
     9541 gattttcagg acaagtgtat tttggctggg attgatgttc ccattcatgc aggaattatg
     9601 ccaattctga atcgaaatca ggctctccga ctcttgaaga cttgtgagaa tatccatctt
     9661 ccacgcaaat ttaaagccat cttagacaag tatgagcatg accctgagtc gctcagagca
     9721 gcaggacttg cctatgcagt ggaccaaatc gtggacttgg taactcagga tgttgccggt
     9781 gtgcatctct atacgatgaa taatgctgat acagcaaaat acatccatca agcaacccat
     9841 gccttgttta atcaccagtc tctaggataa taaaagcaaa ccattcttct caggtgaggg
     9901 gaatggttcc tttttaatgg taaagacctc actttttaag aaaaatatga taaaataaat
     9961 tctgtacgta cttgatacaa agatgaaggt attaaataat acaatgcatt taaactgtaa
    10021 gatttaacga cacgagtgag tcaaatcgat gttatttgac gagagagtta gtaaagcatt
    10081 tagctaatcg cccgatagcg attagcgtga aagctttaga tactttagta ttaaaccttt
    10141 ctaatgatgt atcttgaaaa ctgaacttgc ctacaactct gtggaaaaag ataaatctcc
    10201 ctaggagcag tcgctccgtc gttcgatttc ctattttcct ttgagttgct tgacggcttg
    10261 gtatcttgat gacttgaatt ttggtctcat ttcttaggaa aaaagataag cttcctagca
    10321 ctcgtcgagt gcgacgtcac cttcctattt ttctacagaa atgttcggca agccgaaccg
    10381 tccaaaatat cttgtgtaat tgaacacggc cgaaaagctg tgtaaaaaag ataaactgtc
    10441 ttgtcttcat cgaagacttc gtcagtttcc tatttttact ttgcttttga cgtccttggt
    10501 atcttgatct ttgtaggcaa ggcgtataat ttcatcaatc caaaggggat taaaatggca
    10561 aaacaagtgt ttcaaacgac ttttgcgggt cgtgagttaa ttgtagaaac tggtcaggtt
    10621 gctaagcaag caaatggctc tgttgtcgta cgttacggtg agtcaactgt cttgactgct
    10681 gccgttatgt ctaagaaaat ggcaactggg gatttcttcc cactccaagt caactacgaa
    10741 gaaaaaatgt atgcggctgg gaagtttcct ggtggcttta tgaaacgtga aggacgtcct
    10801 tcaacagatg cgaccttgac agcgcgtttg attgaccgtc cgattcgtcc tatgtttgcg
    10861 gaaggtttcc gtaatgaagt ccaagtcatc aatacagtgc tttcttatga tgaaaatgcg
    10921 tctgcaccaa tggctgctat gtttggttca tctttggcac tgtctatttc agatattcca
    10981 tttgacggac caattgctgg ggtacaagtg ggatatgtag atggccaaat catcatcaac
    11041 ccaagtcaag aacaagcaga gcaatctctt cttgaattga cagtagctgg aaccaagcac
    11101 gctatcaaca tggtagagtc tggtgctaaa gaattgtcag aagaaatcat gttggaagcg
    11161 ctccttaaag ggcacgaagc tgtcaaagaa ttgattgcct tccaagaaga aatcgttgct
    11221 gctgtcggta aagaaaaagc agaagtggaa ttgcttcacg tggatgctga attgcaagct
    11281 gaaatcattg cagcctacaa cagtgacctc caaaaggcag ttcaagtaga agagaaattg
    11341 gcccgtgaag ctgcgactca agtagtgaaa gaccaagtga ctgccgttta cgaagaaaaa
    11401 tatgcggacc acgaagaatt tgaccgtatt atgcgtgatg tggctgaaat cttggaacaa
    11461 atggaacacg cagaagtgcg acgtttaatt acagaagaca aggtgcgtcc tgatggtcgt
    11521 aaggtcgatg aaatccgtcc tttggatgcg gttgtcgact tccttcctcg tgtgcacggt
    11581 tcaggtctct tcactcgtgg acaaacgcaa gccctttctg tcttgacctt ggctccgatg
    11641 ggagaaactc aaatcattga tggtttggat ctggagtaca agaaacgctt tatgcaccac
    11701 tataacttcc ctcaatattc tgtaggggaa acaggtcgtt acggtgcgcc aggtcgtcgt
    11761 gaaatcggtc acggtgccct tggtgagcgt gctcttgctc aagtcttgcc aagcttggaa
    11821 gaattcccat acgctatccg tctagtagca gaagttttgg aatcaaacgg ttcttcatct
    11881 caagcttcta tctgtgcggg aactcttgcc cttatggctg gtggtgtgcc aatcaaggcg
    11941 ccagtagctg gtattgctat gggacttatc tcagatggaa ataactacac agtattgaca
    12001 gatatccaag gtttggaaga tcactttgga gatatggact tcaaggttgc aggtactcgt
    12061 gatgggatta cagcccttca aatggatatc aagattcaag ggattactgc agaaatcttg
    12121 acggaggctc ttgctcaagc caagaaagcg cgttttgaaa tccttgatgt cattgaagca
    12181 accattccag aagttcgtcc agaattggct ccaactgctc cgaaaattga tacgatcaag
    12241 attgatgtgg acaagattaa gattgtcatc ggtaagggtg gagaaaccat cgacaagatt
    12301 atcgctgaaa caggtgttaa gattgatata gacgaagaag gaaatgtgtc tatctactct
    12361 agtgaccaag atgctattaa ccgtgccaaa gaaattattg ctggtttggt tcgtgaagcc
    12421 aaagtggatg aagtttaccg tgctaaagtc gttcgtatcg agaaatttgg tgcctttgtt
    12481 aacctctttg ataagacaga tgcccttgtt catatctctg agatggcttg gactcgtacc
    12541 aatcgtgtag aggatttggt agaaatcggg gatgaagttg atgttaaggt tatcaaaatt
    12601 gatgaaaaag gccgtatcga tgcctctatg aaggctcttc tacctcgtcc gccaaaacct
    12661 gagcatgatg aaaaaggtga aaagtctgag cgccctcacc gcccacgtca tcaaaaggat
    12721 cacaaaccta agaaagaatt tacagaaaca ccaaaagatt cagaataaga aaaggagaaa
    12781 tgtatggggt ggtggcgcga aaccattgat attgtaaaag aaaatgatcc agcggcccgc
    12841 accactttgg aggttttgct gacttatcca ggtgtcaagg ccttggcggc ccaccgtctc
    12901 tcgcattttc tctggaagca cggcttcaaa ctattagctc gtatgtacag tcagttttgg
    12961 cgcttttgga ctcagattga gattcatcca ggagcccaga ttgattcagg tgtttttatt
    13021 gaccatggtt ctggtctggt gattggagag acagcgattg ttgaaaaagg cgttcttctc
    13081 tatcacggag tgactctcgg gggaacaggg aaagactgtg gcaaacgcca tccgactgta
    13141 cgaaagggag ccctcatatc agcccatgcc caagttatcg ggcctgtgga aattggtgaa
    13201 aatgccaagg tcggtgctgc agcagttgtc gtagcagatg tacctagtga tgtgacggtt
    13261 gtcggtattc cggccaagat tgtccgtctt catggtaaga aagatgagcc tgttattcac
    13321 gaagtcgaag aaaaacggga gtattatgtc aataaactcg agcaggctaa agatgccagt
    13381 cacagatcgt ctggtttgta gaggatacct atatgattca agcaagaaac aagttaagcc
    13441 aagaggagct atctgaggcg aaaaaagtaa ttaactgttg ccaaaactat gacggtacct
    13501 atcgcgatcc ctatctctct aacatgctta attttgaccc aaacatgccc gcctttttcc
    13561 tttattatga aaaaggcaaa cttgttggtt tattaactgt ctatgcagat gaccaagatg
    13621 tagaagtgac gatattggtt catccaggtc atcgccgtca ggggattgcg cgtgcattgt
    13681 ttactagttt tgagagagaa acagcttctt tccccattcg gtcagtcact tttcagacag
    13741 aacgtatttt tttagagaat catcctgact ttgccagtaa ctggggacta atcgaggatg
    13801 aagagacaga aacttggtta ggtaaggata gaagacctta tccgttagca aatgtttccc
    13861 atcttgaagt tttgttagca gatagttcgt atcaggatca aattagtcaa ttaaaatttc
    13921 aggcattttc agaggaacat gaatcgagag aagttgtgga tagatatgtc gctgaagctc
    13981 tgaaggatcc agaaagtcgc ttatatattt tgttaaaaga cggtcaggtt attgggactt
    14041 gcacggtaga tttatcgact aatacgaatt acttctacgg tttagcaata tcggaacctg
    14101 aacgtgggaa aggctatgga agctacttag caaaatccct cgtcaaccaa ctaattgagc
    14161 aaaatgacaa ggaatttcag attgcagtgg aagatagcaa tgtaggtgcc aaacgtttgt
    14221 atgaaaaaat tggctttgtc aaacagacac aggtggttta tctgaatgag aaaggagcaa
    14281 gggattccga agtgtagaga cattcggact gaaatttact tgagctctta gtttagtgat
    14341 gaaactaaca gttcttggat tttagctttc ctgattatga tttatgatta aaatctatga
    14401 caccatgtct cgtgatttgc gagaatttgt cccgattgag gacggcaaga tcaagatgta
    14461 tgtttgtggg ccaaccgtgt acaactatat tcacgtggga aacgcccgtt cgacggtagc
    14521 ttttgatacg attcgtcgct attttgagta ccgtgggtat aaggttgcct atatttccaa
    14581 ttttacagat gtggatgata agattatcaa ccgtgccagg gaagaaggca tcacacctca
    14641 ggaggttgcg gataagtaca tcgctgcctt tcgtgaggat gtgacggcct taggcatgaa
    14701 acctgcgact cgccatccgc gtgtagtgga gtttatggca gacatcatcc gttttgtgga
    14761 agacttgatc gagaaaggct ttgcctatga gagtcaaggg gatgtctatt tccgtgtaga
    14821 aaaatcccac aactatgcta aattggctaa taaaaccttg gaagatttgg agctaggtgc
    14881 ttcaggtcgt accgatgaag aaacggctcg taaggaaaat cctgtagact ttgctctatg
    14941 gaaatcttcc aaaccaggtg agatttcttg ggatagtcct tggggacctg gacgtccggg
    15001 ttggcatatt gagtgttcag tcatgtcgac agagatttta ggtgatacca ttgatatcca
    15061 cggtggtgga gctgacctag agtttccaca ccacaccaat gaaattgccc aatctgaagc
    15121 taaaacaggc aaggcttttg ctaactactg gatgcacaat ggctttgtca atatcgacaa
    15181 tgtcaaaatg tctaagtcct tgggtaactt cattacggta cacgatgccc ttaaaactct
    15241 tgatgggcaa gtacttcgtt tcttctttgc gacccagcac taccgtaagc ctatcaactt
    15301 cacggaaaag gcagttcgcg atgccgagac caatctcaag tatctgaaga atacttacga
    15361 acaaccattt acaggaaacg tggatgccca agagttacaa aactttaaag ataagtttgt
    15421 agcagctatg gatgaagatt ttaatgctgc caacggtatc acagttgtct ttgaaatggc
    15481 caaatggatc aactcaggga actatgatgc aagtgtcaag caagctcttg cagatatgtt
    15541 agaaattttt ggaattgtct ttgttgagga agttttggat gcagagattg aagacttgat
    15601 tcaaaaacgc caagaggcgc gtgccaatcg tgactttgag acagcagacc aaatccgtga
    15661 ccaattggtt actcaaggaa ttaagctcct tgataccaag gatggagtga ggtggacacg
    15721 tgattgatgt caatctcatt aacgggattg cgctagcctt tgagggagat gcggtgtatt
    15781 ctatgtatat tcgccgccac ctcatcctca aaggtatgac caagcccaat aaactccacc
    15841 aagaggcgac caagtacgtg tcagccaagg ctcaggctcg tctgattgct ctcatgttgg
    15901 aggagcagat cctaacggaa aaagaagaag aaatctacaa acgtggccgc aataccaata
    15961 gtcacacaaa ggctaaaaat gcagatgtcg tgacttatcg tatgtccacg ggatttgaag
    16021 cagttatggg ctatctccat atgactgaga atctggaacg tcttgagagt ttggtttcat
    16081 ggtgcatcca aaaagtggag ggctagaaca tgagggcaaa agaactacaa gactggtttc
    16141 ctgaggctcg gatttcagac caaccagtag agaaagaggg ctatctcacg cttcctttag
    16201 cttctcagca gtggattttg ctggaggaag ctgggctcag cgagcgtgaa aagcagttgg
    16261 ttgccctttt gacccagcag gagcaggctc gttcgctaaa cccttggtat tcctatctgg
    16321 ttgagggcaa gggacaggca ccgcaagttt ttaaaaagat tcagttggtt tattgccatc
    16381 tttcttattt tcagcaggaa aatctgactt cttggctaga tatgatgcgg actctttttc
    16441 cgaattgtca gacagtgcta caggtcggag ctcaggatta tgttttcgtg cttcaacaag
    16501 acaaatacac ttctgtaaga gatattttga gtgatacgat tgaagcggtt gagtatgact
    16561 ttggacttcg tctttctatc atgttgggtc aggtttggtc tcagacagga catcaagccc
    16621 tatcagactt aatcaaagct gagcgggatt tgttcaagac atggtggcgt cagggtcacc
    16681 aaggtgttca tactttttct cagctctatc tttggagtat gggagaaaga ctcgtggact
    16741 tgaagccaat taaagaatgt ctacaccaga tgattttgga tcaagatcag attcaggaaa
    16801 tcattctctc tctttgggaa aatagtgctg ttctcactaa aacagcccag caactctatc
    16861 tgcaccgcaa ttctctccaa tacaagattg ataaatggga agagttgaca gggcttcagt
    16921 tgaaagagtt gaccgacctg accttgtgtt atcaattgat tttaggttct ttgtcaacta
    16981 tagttggttt gtaaagaagt taata
//
LOCUS       DAVLBE010000037        16711 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.037, whole genome shotgun sequence.
ACCESSION   DAVLBE010000037 DAVLBE010000000
VERSION     DAVLBE010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16711)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16711)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16711
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.037"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            <1..433
                     /locus_tag="VXB91_001389"
     CDS             <1..433
                     /locus_tag="VXB91_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0470831.1"
                     /translation="FHLIGEDFATKLTNEYKKISQFRSKVSQSPWIKYLEISSFILTI
                     FPSILYGTVDNRVLALIFLIKICVDTTIKFLFIRLFDTSTLMKRRIFFLFALDVIVYL
                     FLGYLLVIQKAGYLFSVLLLFSNFSVPFIKEKEFELFKNSK"
     gene            1568..2071
                     /locus_tag="VXB91_001390"
     CDS             1568..2071
                     /locus_tag="VXB91_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0470832.1"
                     /translation="MKLLDCILDYQERFNRKACQVSTNYKYLETFKVNFCLTDLHHLF
                     GLHKITRDYASQTKPAIQAGVFILEDFRNILLYNDVIERISLYEFIGDIFYFKITSCC
                     IVAKDLSKNTMKLDVIFFEDKNKRSAVLGLRRDKSGVFKPVTLHFTSAKKYAKVRKTD
                     VKEMKWL"
     gene            2357..4149
                     /locus_tag="VXB91_001391"
                     /pseudo
     CDS             2357..4149
                     /locus_tag="VXB91_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035320.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
     gene            4549..5670
                     /gene="mnmA"
                     /locus_tag="VXB91_001392"
     CDS             4549..5670
                     /gene="mnmA"
                     /locus_tag="VXB91_001392"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HEV0470833.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAITLGADYVATGHYARVARDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLEKPEVRKLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQ
                     GFYHDSLMSTSLEASQVHFTREMPEEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
     gene            5811..6266
                     /locus_tag="VXB91_001393"
     CDS             5811..6266
                     /locus_tag="VXB91_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV0470834.1"
                     /translation="MTQQDFRTKVDNTVFGVRATALIVQNHKLLVTKDKGKYYTIGGA
                     IQVNESTEDAVVREVKEELGVKAQAGQLAFVVENRFEQYGVSYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKLQNIQLVPAFLKTALPDWEGQLRHIHLEE"
     gene            6276..8189
                     /gene="mnmG"
                     /locus_tag="VXB91_001394"
     CDS             6276..8189
                     /gene="mnmG"
                     /locus_tag="VXB91_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HEV0470835.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMIDEILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDEAPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWARFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEDLDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
     gene            complement(8396..8488)
                     /locus_tag="VXB91_001395"
                     /pseudo
     CDS             complement(8396..8488)
                     /locus_tag="VXB91_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(8542..10221)
                     /locus_tag="VXB91_001396"
     CDS             complement(8542..10221)
                     /locus_tag="VXB91_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEV0470836.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     VCTGDFKFDFTPVGEPADLHRMAALGEEGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEVLILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLCLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(10223..10456)
                     /locus_tag="VXB91_001397"
     CDS             complement(10223..10456)
                     /locus_tag="VXB91_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HEV0470837.1"
                     /translation="MIYKVFYQETKERSPRRETTRALYLDIDASSELEGRITARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFEITEF"
     gene            10736..10951
                     /locus_tag="VXB91_001398"
     CDS             10736..10951
                     /locus_tag="VXB91_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0470838.1"
                     /translation="MYNLFAFAIGARLVAFIVFVACVYAGNLLFAKLERRQTKFLWKM
                     TFVTLYSLFLLLVTYVVWFVFYFELNA"
     gene            complement(11274..11426)
                     /gene="cibB"
                     /locus_tag="VXB91_001399"
     CDS             complement(11274..11426)
                     /gene="cibB"
                     /locus_tag="VXB91_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HEV0470839.1"
                     /translation="MMKDLNNYREISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            complement(11428..11613)
                     /gene="cibA"
                     /locus_tag="VXB91_001400"
     CDS             complement(11428..11613)
                     /gene="cibA"
                     /locus_tag="VXB91_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
                     /protein_id="HEV0470840.1"
                     /translation="MTNFDILDNQFLSLSENELSDIDGGLAPLVIFGVAVSWKAIAGG
                     TALIGSGLAAGYFLGGD"
     gene            11791..12474
                     /gene="tsaB"
                     /locus_tag="VXB91_001401"
     CDS             11791..12474
                     /gene="tsaB"
                     /locus_tag="VXB91_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HEV0470841.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQVLAETTINIKKNHSITLMPAID
                     FLMASLDWTPKDLDRIVVAEGPGSYTGLRIAVATAKTLAYTLNIELVGMSSLLALVPH
                     QQEGLFVPLMDARRNNVYAGFYENAKPVMAEAHLSFEEVLEKVKGTSQVTFVGEVGPF
                     VEQIQKHLPRTDYKETLPNAANLALLAWDKEADSLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            12471..12908
                     /gene="rimI"
                     /locus_tag="VXB91_001402"
     CDS             12471..12908
                     /gene="rimI"
                     /locus_tag="VXB91_001402"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HEV0470842.1"
                     /translation="MIEIKRIQQQPDLAQAIYAVMAAVYLVSPWTLEQIQADLSQDQT
                     WYVLAYDGAEVIGFLAVQENIFEAEVLQIAVKGAYQGQGIASALFAQLPTDKEIFLEV
                     RKSNQRAQAFYKKEKMAVIAERKAYYHDPVEDAIIMKREIDEG"
     gene            12898..13908
                     /gene="tsaD"
                     /locus_tag="VXB91_001403"
     CDS             12898..13908
                     /gene="tsaD"
                     /locus_tag="VXB91_001403"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HEV0470843.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKAFA
                     WAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLHHNAEQKGESLSTEDLCASFQAAVMDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFAGWDLNAKPSLAFDT
                     ME"
     gene            complement(13948..15254)
                     /locus_tag="VXB91_001404"
                     /pseudo
     CDS             complement(13948..15254)
                     /locus_tag="VXB91_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011680908.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(15530..15881)
                     /locus_tag="VXB91_001405"
                     /pseudo
     CDS             complement(15530..15881)
                     /locus_tag="VXB91_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(15988..16281)
                     /locus_tag="VXB91_001406"
                     /pseudo
     CDS             complement(15988..16281)
                     /locus_tag="VXB91_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT         5065 a         3107 c         3742 g         4797 t
ORIGIN      
        1 ctttcattta attggggaag attttgctac taaattgact aacgaatata agaaaattag
       61 tcagtttaga agcaaggtgt ctcaatctcc ttggataaaa tatttagaga tttctagttt
      121 tatattaact atatttccat ctattcttta cggtacagtt gataatcgtg tattggctct
      181 tatctttttg ataaaaattt gtgtagatac tacgataaaa tttttattca tcagattatt
      241 tgacacaagt actttaatga agaggagaat attttttctt ttcgcattgg atgttatagt
      301 ttacttattt ttaggatatc ttttagtgat tcaaaaagca ggctatttgt tttcggtttt
      361 acttcttttt tctaattttt cagttccatt tatcaaagaa aaggaattcg aattatttaa
      421 aaatagcaag taatagaaac ataggttaaa tcttagaacg gcttaaaatc agatatgata
      481 aagggaaata gtcttatcta ggtaactaag tgctacaaac acagtcgagg atcacttgtt
      541 aggattacat tttaatcatg cttaataaga atggagaatt cctatgggga ttgtattact
      601 ctgaagtttc gaatacctta gttctcgtga ttttgagctg ttctagcttt agaatccttc
      661 agaacgtaaa attttaagca gtcaaagact tagaatagcc tggaaacatt tattttatag
      721 caattctaaa cttagaattg ctcatatata tgtatttgag ctgctcgata gttaggacag
      781 ctctattctg agaaatctga gctatcaatg cttcagaata gtatttcgcc aatggttttt
      841 attgaagagg tgattgtgtt atgatagtct aaaataaaat tgatttaata gagtaaatgg
      901 agaatcgtta catgaaacat ttttttgcag gaattggtga gataaaactt gttggctact
      961 tattgtatat atgtgtagga ctagcccctc tttttcatat atatgtcata ggttcggaac
     1021 tgagttttgt gaaaatagtg ttatctattt tgggagttat atttgtaagt atgttaacta
     1081 ttgctcgaat ttatcggact tttctataaa gaatagtttg gacttgaact gtatctaaaa
     1141 acagaggttg gtcgattatc agcctctttc ttgtcgttga aaagagtgag atatattgac
     1201 ttttgaaaaa aagatgtcat aattgagttg ggataaacct aaaagtaata tagtagattg
     1261 aatctggaat agtccgttat gactgttaaa atatttctag aaattaattt gactttccta
     1321 atcgatttgt tcacatcttg tttcaatcta ctatactttc tcgttaaacc gttcggcaat
     1381 tcatggtgac atggacacat agtagtaagc acactatgtg gcttggcaga gctaaaaact
     1441 gttcccttgc gataagccta ataagcacaa catagggagt tagagaagcc gactctaatc
     1501 aaccactttg ggcagtagtg agaactgccc cgtgcttttt tattttgaga aaatatggag
     1561 tttgtcgttg aaattacttg attgtatttt ggattatcaa gaaagattca atagaaaagc
     1621 atgtcaagta tcaacgaatt ataagtattt agagactttc aaagtgaatt tttgcctgac
     1681 tgatttacat catttatttg gcttacacaa aatcacacga gattatgcta gtcaaacaaa
     1741 acctgctatt caagctggtg tttttatttt agaagatttt agaaatatcc tattgtacaa
     1801 tgatgtaatc gaaaggatat ctttatatga gtttataggt gatattttct attttaaaat
     1861 aacaagttgt tgcatcgtag ctaaggattt atctaaaaat actatgaaat tggacgtcat
     1921 attttttgag gataaaaata aaagatccgc agttttaggt ttacgaagag acaaaagcgg
     1981 agtatttaaa ccagttactc tacattttac aagcgctaag aaatatgcta aagttcgtaa
     2041 aacagatgtg aaagaaatga aatggctata aagattgtcc gcaggcttaa gcttgcgttt
     2101 tttgttgttt aacgaaatta aaaaacaagc tctctcatcg gaaatgtttt tataggaatg
     2161 aaggaagatg atgctatgtt taaaaagaga atcgaaaagg gcaaaagtag tgtctttatc
     2221 tttttggagt agaagcttat gatatagaaa tttgtaataa aaatgtaata taaaacattt
     2281 gacaaatatt tacgggggga gtatacttaa tataagtata gtctaaaaat gactatcaga
     2341 aaagaggtaa atttagatga ataagaaaaa aatgatttta acaagtctag ccagcgtcgc
     2401 tatcttaggg gctggttttg ttacgtctca gcctactttt gtaagagcag aagaagctct
     2461 ccacaagttg tcgaaaaatc ttcattagag aagaaatatg aggaagcaaa agcaaaagct
     2521 gatactgcca agaaagatta cgaaacggct aaaaagaaag cagaagacgc tcagaagaaa
     2581 tatgatgagg atcagaagaa aactgaagag aaagcgaaaa aagcagaaga agctgctaag
     2641 gaagtagatg atgctagttt agcggtgcaa aaagcttatg tggaacaaag aaaagcacaa
     2701 gaagaaaaaa ataaacattc aggaaatcca gagtacgcta aaaaattagc agaagcagat
     2761 aaaaaaataa ctgaggagac gactaaacta accgatgctc agacaaaatt tcaatctgtt
     2821 caagcaatgg tagttcctga gccagagcag ttggctgaga ctaagaaaaa agcagaagaa
     2881 gctaaagcag aagaaaaagt agctaagaga aaatatgatt atgcaactct aaaggtagta
     2941 ctagcgaaga aagaagtaga ggctaaggaa cttgaaattg aaaaacttca atatgaaatt
     3001 tctactttgg aacaagaagt tgctactgct caacatcaag tagataattt gaaaaaactt
     3061 cttgctggtg cggatcctga tgatggcaca gaagttatag aagctaaatt aaaaaaagga
     3121 gaagctgagc taaacgctaa acaagctgag ttagcaaaaa aacaaacaga acttgaaaaa
     3181 cttcttgaca gccttgatcc tgaaggtaag actcaggatg aattagataa agaagcagaa
     3241 gaagctgagt tggataaaaa agctgatgaa cttcaaaata aagttgctga tttagaaaaa
     3301 gaaattagta accttgaaat attacttgga ggggctgatc ctgaagatga tactgctgct
     3361 cttcaaaata aattagctac taaaaaagct gagttagcaa aaaaacaaac agaacttgaa
     3421 aaacttcttg acagccttga tcctgaaggt aagactcagg atgaattaga taaagaagct
     3481 gctgaagctg agttggataa aaaagttgaa gctcttcaaa acaaagttgc tgatttagaa
     3541 aaagaaatta gtaaccttga aatattactt ggaggggctg attctgaaga tgatactgct
     3601 gctcttcaaa ataaattagc tactaaaaaa gctgaattgg aaaaaactca aaaagaatta
     3661 gatgcagctc ttaatgagtt aggccctgat ggagatgaag aagaaactcc agcgccggct
     3721 cctcaaccag agcaaccagc tccagctcct gcaccaaaac cagagcaacc agctccagct
     3781 cctgcaccaa aaccagagca accagctcca gctcctgcac caaaaccaga gcaaccagct
     3841 cccgcaccaa aaacaggctg gaaacaagaa aacggtatgt ggtacttcta caatactgat
     3901 ggttcaatgg cgacaggatg gctccaaaac aacggttcat ggtactacct aaacgctaac
     3961 ggttcaatgg caacaggttg ggtgaaagat ggagatacct ggtactatct tgaagcatca
     4021 ggtgctatga aagcaagcca atggttcaaa gtatcagata aatggtacta tgtcaatggc
     4081 ttaggtgccc ttgcagtcaa cacaactgta gacggatata ctgtaaatga aaacggtgaa
     4141 tgggtttaag ccgattaaat taaatcatgt taagaacatt tgacatttta attttgaaac
     4201 aaagataagg ttcgattgaa tagatttatg ttcgtattct ttaggtacct gtcttatgat
     4261 ttcaggaaat gtcattaaaa aacgactcct tttctctaac ttgaaaaata gattagagaa
     4321 aatgggttgt tttatttatt atagttattt gaatgaagat aagaagaagg tatactcacg
     4381 tcattcacat aatctgtata ttgactataa gttttaaaaa acaattttta agctcttcct
     4441 tgtcttctct aaccaagcgt gttataatga atactgctca agcgaccttc aatcgtgaag
     4501 cacacacgac cttcaatcgt gaataaacga atagatggga gacttaccat gagtgataac
     4561 tctaaaacac gtgttgtcgt ggggatgagt ggtggtgttg attcgtcggt gacggctctt
     4621 ttgctcaagg agcagggcta cgatgtgatc ggtatcttca tgaagaactg ggatgacaca
     4681 gatgaaaacg gcgtctgtac ggcgaccgaa gattacaagg atgtggttgc ggtggcagac
     4741 cagattggca ttccctacta ctctgtcaat tttgaaaaag agtactggga ccgcgttttt
     4801 gagtatttcc tagcggaata ccgtgcaggg cgcacgccaa atccggacgt tatgtgcaac
     4861 aaggaaatca agttcaaggc ctttttggac tatgccataa ccttgggggc agactatgta
     4921 gcgactgggc attatgctcg agtggcgcgt gatgaggacg gcactgttca catgcttcgt
     4981 ggcgtggaca atggcaagga ccagacctat ttcctcagcc aactttcgca agaacaactt
     5041 caaaaaacca tgttcccact aggacatttg gaaaagcctg aagttcgaaa actagcagaa
     5101 gaagcaggcc tttcgactgc taagaagaaa gactcgacag ggatttgctt tatcggagaa
     5161 aagaacttta aaaacttcct cagcaactac ctgccagctc agcctggtcg catgatgact
     5221 gtggatggtc gcgatatggg cgagcatgca ggtcttatgt actatacaat cggtcagcgt
     5281 ggcggactcg gtatcggtgg gcaacacggc ggtgacaatg ccccttggtt cgttgtcgga
     5341 aaagatctaa gcaagaatat tctctatgta ggacaaggat tctaccatga ttcgctcatg
     5401 tcaactagcc tagaagccag tcaagtccac tttactcgtg aaatgccaga agagtttacg
     5461 ctagaatgta cggctaaatt ccgttaccgt cagcctgact ctaaggtgac cgtccatgtc
     5521 aaaggagaca aggcagaggt catctttgcg gaaccacaac gcgcgattac accaggacag
     5581 gcagttgtct tttacgatgg cgaagagtgt ctaggtggtg gtttgattga caatgcttac
     5641 cgcgatggac aagtttgtca gtacatttag attgacaaat tttctcaatt tgctacaata
     5701 ataacagcaa tagaaatgat ggtcaaagct catggatgtt gcaggctttt ttgtcctgca
     5761 cttctttgta gttttgactg tttttgtgtc gtttaaggga aaggacaaga atgactcaac
     5821 aagactttcg gacaaaagta gacaatacgg tttttggtgt tcgggcgaca gccttgattg
     5881 tccaaaatca caagcttcta gttaccaaag acaagggcaa gtattacact attggaggtg
     5941 cgattcaagt caatgaaagc acggaagacg cggtagtccg tgaagtgaag gaagaactgg
     6001 gtgttaaagc tcaagctggg cagctagctt ttgtggttga aaatcgtttt gaacaatacg
     6061 gtgtttccta tcacaatatc gagtttcatt atctggtgga tttgcttgaa gatgccccat
     6121 tgaccatgca ggaagatgag aaaaggcagc cctgtgagtg gattgacttg gataagctcc
     6181 agaatatcca gctagttcca gcctttttaa aaacagccct accagattgg gaaggccaac
     6241 taagacacat tcatcttgag gaataggaga gaaacatgac ttatcatttt actgaagaat
     6301 acgatattat tgtaattggt gcgggacacg ctggggttga ggcttccttg gccgctagcc
     6361 gtatgggctg taaggtcctg cttgcgacca tcaatattga aatgctggct ttcatgcctt
     6421 gtaatccctc tatcggtggt tctgccaagg ggattgtcgt gcgtgaagtc gatgccctcg
     6481 gtggcgagat ggccaaaacc attgacaaga cttacatcca gatgaagatg ctaaacacag
     6541 ggaaggggcc agctgtccgt gcccttcgtg cgcaggctga caaggaactt tactctaagg
     6601 agatgcgcaa gacggttgaa aaccaagaaa atctgaccct tcgtcaaacc atgattgatg
     6661 agattttggt ggaagatggc aaggttgtcg gtgtgcgtac agccacccat caagaatatg
     6721 ctgctaaggc tgttattgtg acgacaggga ctgctctccg tggggaaatt atcatcggag
     6781 acctcaagta ctcatcaggt cctaaccaca gcttggcttc tattaaccta gctgacaatc
     6841 tcaaggaact gggtctcgaa atcggtcgtt tcaagacagg aacccctcca cgcgtcaagg
     6901 cctcttctat caactacgac gtgacagaaa tccaaccagg agatgaagcg cctaatcact
     6961 tctcatacac ttcacgtgat gaggattatg tcaaggacca agtgccatgc tggttgacct
     7021 ataccaatgg taccagtcat gagattattc aaaacaacct ccaccgtgcg cctatgttta
     7081 caggtgtggt caagggagtg gggcctcgtt actgtccgtc gattgaagac aagattgtgc
     7141 gctttgcgga caaggaacgt caccaactct tccttgagcc agaagggcgc aatactgagg
     7201 aagtctatgt tcaaggactt tcaaccagtc tgcctgagga tgtccagcgt gacttggttc
     7261 attccatcaa aggtttggaa aatgcagaga tgatgcggac aggttatgct attgagtatg
     7321 atatggtctt gcctcatcag ttgcgtgcga ctttggaaac caagaaaatc tcaggtctct
     7381 tcactgctgg tcagacaaat ggaacatcag gttacgaaga agctgctggc caagggatta
     7441 tcgcgggtat caatgcggct ctgaaaatcc aaggcaagcc tgaattgatt ttgaagcgca
     7501 gtgatggtta tatcggggtg atgatcgacg acttggtgac caagggaacc attgaaccct
     7561 accgtctctt gaccagtcgt gctgaatacc gtctcattct tcgtcatgac aatgctgata
     7621 tgcgcttgac tgagatggga cgcgagattg gccttgtgga cgatgaacgc tgggctcgtt
     7681 ttgaaatcaa gaaaaatcaa tttgataatg agatgaagcg cctagacagt atcaaactta
     7741 agccagtcaa ggaaaccaat gccaaggttg aggagatggg cttcaaaccc ttgaccgatg
     7801 cagtgacagc caaggaattc cttcgccgtc cagaagtttc ttaccaagat gtggtggcct
     7861 tcatcggacc agctgcagaa gacttggatg acaagattat cgaattgatt gaaacagaaa
     7921 tcaagtatga aggctatatt tccaaagcca tggaccaggt tgccaagatg aaacgcatgg
     7981 aagaaaaacg cattccggcc aatatcgact gggatgacat tgattctatc gcaaccgaag
     8041 cccgtcagaa gttcaaactc atcaatccag aaaccatcgg ccaagccagc cgtatttcgg
     8101 gagtaaaccc agcagatatt tctattttga tggtgtatct ggaaggtaaa aatcgtagta
     8161 tttctaaaac tcttcaaaaa tcaaaatgat acgtcgtcgg cttcttacga atgagttcaa
     8221 agcttggctt tgattcatct ccagcctccc atagtttccc gaactatggg agctaactca
     8281 agttatgctt tcgcttagcc ttctagtctg atttcgattt ttattgatac tcttcgaaaa
     8341 tctcttcaaa ccgcgtcaac gtcgccttgc cgtaggtatg gctactgact tcgtcagttc
     8401 tatctacaac ctcaaagcag tgctttgagc aacctacggc tagcttccta gtttgctctt
     8461 tgattttcat tgagtatgag ttttaatctc aaaagaaagc atagagaaaa acagctccga
     8521 ggacggggct gttttcttgc tttattcttc atctggtgtg aggatcatcg ggatgatgat
     8581 cggttcacgt tcggtatttt catagaggaa ggggcgaata gcgttgacaa tggcaccatt
     8641 gacagattgc acgctggcat ccttattttt cagtgcgata cgaatggcat tgaagaggat
     8701 acgctggctt tggcgaatca agtcgccaga ctctctcatg tagacaaagc ctcggctgag
     8761 gatgtctgga ccagacagaa tcatctgcga tttgaagtca acagttgcga ctgccagaac
     8821 gacaccgtct tcagatagat cgcgacgatc tttgaggaca gctgcgccaa tttcaccgat
     8881 acgatttcca tcgacataga tatcttgggc gttgaaatga cctgcgatac gagctgagtc
     8941 agcagtaagg gcaagcacat cgccattgct catgataaag atattgtcct tctcaacacc
     9001 agtatccact gctagtccag cgtggacttt ttgcatgcgg tattcaccgt ggacaggcat
     9061 gaagtatttt ggcttaatca agcagagcat gagtttttgc tcttgctgac caccgtgtcc
     9121 agatgtatgg atattgttca ctttaccgtg gataacttcg acaccagctt cagaaatgat
     9181 gttaatcagc ttgttgacgc tagtagtgtt tccagggatg ggactagaag agaagataac
     9241 ggtatcacct ggttgtaatt gtacttgacg gtgggttccg ttggcgatac gagagagagc
     9301 tgccataggc tcaccctgac tacctgtaca gaggataaga acttctcctg caggataatc
     9361 tttgatttca tttggctcga taaaggttcc cttaggagct ttgatgtagc caagatcgat
     9421 tccgttgaca atggcctttt ccatagaacg accaaagacc gcaatcttgc gtccagtctt
     9481 aacagcagct tctgttgcct gctggagacg gaagatattt gaggcaaagg atgcaaagat
     9541 gatacgtcct tcaatacctt ggataatctt cataatggac tgaccaacga ctttttcaga
     9601 gttggtaaag gttggtactt ccgcatttgt cgagtcagac aggagacaga gcacgccttc
     9661 ttcaccaagc gcagccatac gatgcaagtc cgcaggttct ccaactggag taaagtcgaa
     9721 cttaaagtca cccgtacaga cgattttccc ttgaggagta tgaatgacaa tccccaaagg
     9781 ctctggaata gagtgagtcg ttctaaagaa agttgccttg agatttttaa aggtcaactc
     9841 ggtgttgtgg ttgatttcgt aaagtttggc gttgcgcaag aggccgtgtt cttcgagttt
     9901 cccacggatc aaagccaagg caagcggtcc agcgtagata gggacatttg cttgcttgag
     9961 taggaacgga atcccaccaa tgtggtcctc gtgtccgtgt gtgattaaaa cagccttgac
    10021 gcggtcgata ttgtccacga tgtaagagta gtcaggaatg acatagtcga taccaagcaa
    10081 gtcatcttct gggaatttaa tcccagcatc gacgatgata atctcgtctt ggtattcaat
    10141 tccgtaagtg tttttcccga tttctcccag accaccgatg gcaaaaacgc cgacttcttc
    10201 aggtttaaga gtataggcca tattagaact ccgtgatttc gaaggcgcca gtttcttttt
    10261 cgtaatcgag caatttgtca gacaagagtt cgatatattc gatattgtac tctgggcgat
    10321 tttcttcgac aagttggcga gcagtgatgc gaccctcaag ttctgagctg gcatcgatgt
    10381 ctaggtaaag tgcgcgtgtt gtttcacggc gtgggctacg ttcttttgtt tcttgataaa
    10441 aaactttgta aatcatatag ttcctttcta tttacaggtc agcttattcc aaacttttag
    10501 cagatatttg cttgatttca ttccattttg tgtctagatt gaccttgatt cgttacaatt
    10561 atttcaatta taccacaaaa tgaaaaatta gtaaaagacg gaaacgagaa agttagggga
    10621 cgatttcttt ggtaagcgtt tgcaagaata aagaaaatgt attatgttga taacggaagt
    10681 gaaatttatt gcttgtcata attccatata gattttaagt caaggaggtt gccctatgta
    10741 taacttattt gcttttgcta tcggagctcg cttggtagct tttattgttt ttgttgcttg
    10801 cgtttatgcg gggaatcttc tatttgccaa actggaacga cgacaaacca agttcttgtg
    10861 gaaaatgacc tttgtgactc tctactcgct ttttctcctc ctcgtgacct atgtcgtttg
    10921 gtttgtattt tactttgaat taaatgctta gatgccctgc ttatgctggg gttttttgtt
    10981 tggggatgta gagatagtag atttacgaca cgaaaattcc accccatcta tcaagatgag
    11041 gtggtctttg catttttcta acatgacatg acaatggaat tttcaaagct tattattttt
    11101 atgggagtca ttgttctgat caaaaataga gttgaagcat aaaaataaaa caatacaaac
    11161 agataaatcg aatggtaaag ggatggtagt aatgttcaaa tcattgagaa tgctgagcaa
    11221 actgtaagag atgaagacaa taaaatttat ccttctaaaa atgtgtttct tatctagcat
    11281 gacttaccaa actttttacg aaggtctttt ccaatggtat aacctgccat aaataaagcg
    11341 ataccaacac cgacaccaaa gccacccttg atttcttgca attccttatt agaaatttca
    11401 cgataattgt tcaaatcttt catcatatta atctcctcct aaaaaataac cagctgccaa
    11461 accagaacct ataagtgctg ttccacctgc aatagccttc caagatactg ctactccaaa
    11521 gataaccaag ggagcgagac cgccatcaat atctgataat tcattttcag ataaggataa
    11581 aaattgattg tcaagaatgt caaaatttgt cattgaactt tcctcctttt ttcttgttca
    11641 cttttatatt cggaaaagaa aaggaaaagt gagcattttt ttaaattatt tttagttaag
    11701 tgagggcact cttgtctggg ggcaaagaaa attcccatgt gccagctttt gtagtataat
    11761 agtaagcaga caaaaagata ggaatgtgtt atgaaagtat tagcttttga tacgtccagc
    11821 aaggctcttt ctctggctat tttagaggat aagcaggttc ttgccgagac gacgattaat
    11881 attaagaaaa atcacagtat tactcttatg cctgccatcg attttttgat ggcaagtttg
    11941 gattggacac ccaaggattt ggaccgaatc gtggtagctg aagggccggg tagctataca
    12001 ggcttgcgaa ttgcggtagc aactgctaag accttagctt acaccctgaa catcgagttg
    12061 gttggtatgt cgagtctctt ggctctggtg ccccaccaac aagaaggttt gtttgtcccc
    12121 ttgatggatg cgcgtcgcaa taatgtttat gcaggatttt atgaaaatgc caaacctgtc
    12181 atggcagaag cgcacctatc ttttgaagag gtgctagaaa aagtcaaggg tactagtcag
    12241 gtaacctttg tcggagaagt tggccccttt gttgagcaga ttcaaaaaca cttgccaagg
    12301 actgattaca aagaaacatt gcccaatgca gccaatcttg ctcttttagc ttgggacaag
    12361 gaagcagact ccttgcatga ttttgtgccg aattacctca aacgagtcga ggctgaggaa
    12421 aactggctca agaaccatac cgagtctggt gagtcctaca ttaaacgcct atgatagaaa
    12481 tcaagcgaat tcaacaacag cctgacctag ctcaagccat ctacgctgtt atggcagctg
    12541 tttacctagt cagtccttgg actctggagc aaatccaagc agacctgtcc caagaccaga
    12601 cttggtatgt tctggcttat gatggggcag aagtgattgg ttttctagct gttcaggaaa
    12661 atatctttga ggcagaagtc ttgcaaatcg ctgttaaagg agcttatcag ggtcagggaa
    12721 ttgcgtcagc cttgtttgct caattgccga cagataagga gattttcctc gaagtcagaa
    12781 agtcaaatca acgagcgcaa gcattttaca agaaagaaaa aatggcggtc atcgctgagc
    12841 gaaaggccta ctaccatgac ccagtcgagg acgccattat catgaagaga gaaatagatg
    12901 aaggatagat atattttagc atttgagaca tcctgtgatg agaccagtgt cgccgtcttg
    12961 aaaaacgacg atgagctctt gtccaatgtc attgctagtc aaattgagag tcacaaacgt
    13021 tttggtggcg tagtgcccga agtagccagt cgtcaccatg tcgaggtcat tacagcctgt
    13081 atcgaggagg cattggcaga agcagggatt accgaagagg acgtgacagc tgttgcggtt
    13141 acctacggac caggcttggt cggagccttg ctagttggtt tgtcagctgc caaggccttt
    13201 gcttgggctc acggacttcc actgattcct gttaatcaca tggctgggca cctcatggca
    13261 gctcagagtg tggagccttt ggagtttccc ttgctagccc tcttggttag cggtgggcac
    13321 acagagttgg tctatgtttc ggaggcagga gattacaaga ttgttgggga gacacgagac
    13381 gatgcagttg gggaggctta tgacaaggtc ggtcgtgtca tgggcttgac ctatcctgca
    13441 ggtcgtgaga ttgacgagct ggctcatcag gggcaggata tttatgattt cccccgtgcc
    13501 atgattaagg aagataatct ggagttctcc ttctcaggtt tgaaatctgc ctttatcaat
    13561 cttcatcaca atgccgagca aaagggagaa agcctgtcta cagaagattt gtgtgcttcc
    13621 ttccaagcag cagttatgga cattctcatg gcaaaaacca agaaggcttt ggagaaatac
    13681 cctgttaaaa ccctagttgt ggcaggtggt gtggcagcca ataaaggtct cagagaacgc
    13741 ctagcagccg aaatcacaga tgtcaaggtt atcatccccc ctctgcgact ctgcggagac
    13801 aatgcaggta tgattgccta tgccagcgtc agcgagtgga acaaagaaaa cttcgcaggc
    13861 tgggacctca atgccaaacc aagtcttgcc tttgatacca tggaataaag agtggctctt
    13921 tgtcaagtgt agtgggtagg cgaaaagcta caatctggag agtacgaaat tcgtactctc
    13981 ttttttgatg ttcaaagtca tcaaaatccg ttttttaaaa ttgttaaagt tccggaaacc
    14041 aaaggctttg cgcttgataa ccttaatcaa attattggtc gcttcaagtt tagcgttgga
    14101 ataaggcagc ttaagtgcgt tgataatctt atctctatcc cttaaaaaag tccaaaagac
    14161 cgtttgaaaa agcggatgaa ccgttggcag ttcttgctca atcaatccaa agaaatggtc
    14221 ggcattcttc tcttgaaaat gaaagagcag gagttgatag agttcgtagt gaacctgtaa
    14281 tccctcagag taagaaagca gcttatctcg tacttcccga tgggttaagt gcattcgaaa
    14341 cgtgggctga tagaatcgtt tctgacagag cttgaagcta tcctggtgta gtaaatcagt
    14401 ccagtggact gatttagccc gagcctagaa acgaaaaagc gagggttcca aaagcgcttg
    14461 agcgcccgat actccaagga ttttcggtca aattggttca tgatttggat tcgtactcgg
    14521 ttcatagctc ggctcagatg ttggacaatg tggaagcggt caagaacaat cttcgccttt
    14581 ggaaagagtt gcttagcgag ccgataataa gggctgtaca tgtccatggt gatgacctcg
    14641 accagctccc gaacctctct ctgatagcgt tggaaatggt ttcgaatcac cgcatgagtt
    14701 cgcccgtcta aaattgcgag gatggatttg gactcaaaat cttgggcaat gaagctcatt
    14761 ttgctctttt tgaagctata ctcatcccaa ctcataactt ttggcaactt ggtccaatcg
    14821 gtttcaaact taaattccct cagttttcgg atgacggtgg aagttgagac cgccaatctg
    14881 tgggcaatct cagtcataga ctgcttttca aggaggagct gagcgatttt ttgtctcacc
    14941 atgttggaaa tctggcaatt tttcttgaca atggatgttt gagaaacgac caccttaagg
    15001 caattcttgc actgaaagcg gcgctttttg agatgtagta ccgtgggtaa accctgacag
    15061 tcgagaagcg gaattttaga ggctttctgg aagtcgtatt tgatcatctt cccttgacaa
    15121 tgaggacaag gaggagcggg ggaatccaac tttgcctgaa cgactagatg ggtttggtat
    15181 ttcagaacag acaagatttt gatatttttg tctttcaatc cgagcaaatc tgtggtattc
    15241 ttaagttgtt ccatatgaac cctttctaat gagttggtta gacgcttttc attataggtc
    15301 atatggggct ttttttctac aagaaacgac cctataattc ctggggtggg attacccact
    15361 acagaaatta tagagccaaa acattccaaa gtcttgtctg actctggaat gttttctgtt
    15421 cacagttgtt ttgtaactgc ctaataagta accgcgctat aacgaggtat ctaccgagat
    15481 tgtcaattct ccagtatact gttataaaaa acaaaactgg aggatttttt tatgtccccc
    15541 catcgtccca tcgactgttc cgtagctgcc caataacgga gtatagtcgg ctgaaacaag
    15601 aataggacaa aagtgcctca agaaaagcat cgtaatttga caatattatt ctgagatgtt
    15661 tttgatgtaa gcccatattt tctcaatggg attatactcg ggtgaatagg taggaagtgg
    15721 taacagtcta tgccctgctc cttacacatg ttcattctgt gaaaccttgc attgtccata
    15781 atgataaggg atggtgtatc taaagtaggt agtaagaatt tttggaagca agcttcgaaa
    15841 aagtcactcg tcatcgtatc tttataggtc atcggagcca tagtatattg aaacaaaaaa
    15901 gggcattagt acttctataa cagtatcgca atctctggtg tgcgttgtct cgatcttaat
    15961 tcaaataatt atatcttctt ccagagagac taactgcctg ctcaaggctc gatcatattc
    16021 gagataaaaa taggtctcaa cccctgtctc ataaatataa ataggagtca ggtagcttaa
    16081 gtgattcaat tctttaagga accgatttac tttttctggg tcttgttcgc agtaggtaca
    16141 gctctttttt agactatatc ccatagcctt tagagcgtaa tgaatagttg ttggaggaca
    16201 gttgaattca gcagctattt cagtcaaata agcatcggga tgagtttcaa tatagatctt
    16261 taatttatct ctatcaactt tttcaattaa tagtggaagt tttcttaaag ttagtgtgtt
    16321 gaaacgtttt tatacagtgc taaaatttga agtgtagtgc agatgtattt gtaatagtat
    16381 tatagcaatt ctttggagaa ggtcgagaca agagaaaata ggtatctttg agatataagc
    16441 atgatttact ataaaattat tgagttattc ataaaaattt ctctatcaaa tatcataatg
    16501 cgtcgtttaa ggagatggtt acaatgcaat atagttgtgg aaaaataaat attaatatcc
    16561 ctgatggata tggagacatt aaggatatag tgttttcggc tcatattata gttaggtata
    16621 ataatggaca ttgtggaggt atagatccgc atataattgg actttgtaaa aagcagatca
    16681 gaaggatgtc tctatatcct attttgataa t
//
LOCUS       DAVLBE010000038        16441 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.038, whole genome shotgun sequence.
ACCESSION   DAVLBE010000038 DAVLBE010000000
VERSION     DAVLBE010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16441)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16441)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16441
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.038"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            <1..919
                     /gene="lytB"
                     /locus_tag="VXB91_001407"
     CDS             <1..919
                     /gene="lytB"
                     /locus_tag="VXB91_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HEV0470844.1"
                     /translation="KSGGYMAKNETVDGYQLGSDGKWLGGKTTNENAAYYQVVPVTAN
                     VYDSDGEKLSYISQGSVVWLDKDRKSDDKRLAITISGLSGYMKTEDLQALDASKDFIP
                     YYESDGHRFYHYVAQNASIPVASHLSDMEVGKKYYSADGLHFDGFKLENPFLFKDLTE
                     ATNYSAEELDKVFSLLNINNSLLENKGATFKEAEEHYHINALYLLAHSALESNWGRSK
                     IAKDKNNFFGITAYDTTPYLSAKTFDDVDKGILGATKWIKENYIDRGRTFLGNKASGM
                     NVEYASDPYWGEKIASVMMKINEKLGGKD"
     gene            complement(980..2635)
                     /gene="pavA"
                     /locus_tag="VXB91_001408"
     CDS             complement(980..2635)
                     /gene="pavA"
                     /locus_tag="VXB91_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HEV0470845.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEM
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTESLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQETKPCLTETSFSPVPFANQVGEPFANLSDLLDTYYKDKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIGLDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS"
     gene            2740..3237
                     /gene="ybeY"
                     /locus_tag="VXB91_001409"
     CDS             2740..3237
                     /gene="ybeY"
                     /locus_tag="VXB91_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HEV0470846.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAKKLGKEDKEMAVTFVT
                     NERSHKLNLEYRDTDRPTDVISLEYKPELEIAFDEEDLLENPELAEMMSEFDAYIGEL
                     FISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            3218..3613
                     /locus_tag="VXB91_001410"
     CDS             3218..3613
                     /locus_tag="VXB91_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HEV0470847.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFAITGIFTAIKEERNMRKHAVTAL
                     VVILAGFGFQVSRIEWLFLLLSIFLVVAFEIINSAIENVVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            3630..4529
                     /gene="era"
                     /locus_tag="VXB91_001411"
     CDS             3630..4529
                     /gene="era"
                     /locus_tag="VXB91_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HEV0470848.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKVPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPERFLVSEMVREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEREY"
     gene            4578..5402
                     /gene="mutM"
                     /locus_tag="VXB91_001412"
     CDS             4578..5402
                     /gene="mutM"
                     /locus_tag="VXB91_001412"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HEV0470849.1"
                     /translation="MPELPEVETVCRGLEKLIIGKKISSIEIRYPKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFYLTDKVLISHLRMEGKYFYYPDQGPERKHAHVFFHFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQSALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARPSQTLTAEEATAIHDQTIAVLGQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKTGQECVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            5402..6007
                     /locus_tag="VXB91_001413"
     CDS             5402..6007
                     /locus_tag="VXB91_001413"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HEV0470850.1"
                     /translation="MGKIIGITGGIASGKSTVTNFLRQQGFQAVDADAVVHQLQKPGG
                     RLFEALVQHFGQEIILENGELNRPLLASLIFSNPEEQKWSNQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDAQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            5994..7193
                     /locus_tag="VXB91_001414"
     CDS             5994..7193
                     /locus_tag="VXB91_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter PmrA"
                     /protein_id="HEV0470851.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVPFMPIFVENLGVGSQQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            7193..7342
                     /gene="rpmG"
                     /locus_tag="VXB91_001415"
     CDS             7193..7342
                     /gene="rpmG"
                     /locus_tag="VXB91_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEV0470852.1"
                     /translation="MRVKINLKCSSCDSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
     gene            7382..7615
                     /gene="secG"
                     /locus_tag="VXB91_001416"
     CDS             7382..7615
                     /gene="secG"
                     /locus_tag="VXB91_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HEV0470853.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KARGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            7717..10071
                     /gene="rnr"
                     /locus_tag="VXB91_001417"
     CDS             7717..10071
                     /gene="rnr"
                     /locus_tag="VXB91_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HEV0470854.1"
                     /translation="MKDRIKEYLQDKGKVTVNDLAQALGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLTLEIKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     DGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNH
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDVNDILAGDEEKRKEYHK
                     IVPSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERMIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLRIYGTASEISQE
                     ALQDIMRAVEGEPYVDVLSTMLLRSMQQARYSEHNHGHYGLAADYYTHFTSPIRRYPD
                     LLVHRMIRDYGCSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSRSGRGRGSNRRSDKKEDKRKS
                     GRSNDKRKHSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            10034..10501
                     /gene="smpB"
                     /locus_tag="VXB91_001418"
     CDS             10034..10501
                     /gene="smpB"
                     /locus_tag="VXB91_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HEV0470855.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKKQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            10517..11377
                     /gene="tehB"
                     /locus_tag="VXB91_001419"
     CDS             10517..11377
                     /gene="tehB"
                     /locus_tag="VXB91_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HEV0470856.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEAMQTVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIEQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            11450..12403
                     /gene="coiA"
                     /locus_tag="VXB91_001420"
     CDS             11450..12403
                     /gene="coiA"
                     /locus_tag="VXB91_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEV0470857.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHLANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTV
                     SEDKDICRYIRQQLYYQNLFWMKEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIE
                     QDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE"
     gene            12422..14224
                     /gene="pepF"
                     /locus_tag="VXB91_001421"
     CDS             12422..14224
                     /gene="pepF"
                     /locus_tag="VXB91_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEV0470858.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEALKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQIEKLYVYAHMKNDQDTREAKYQEYYAKAMTLYSQL
                     DQAFSFYEPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGTYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYSFTYQEALKKAEDALAVLGEDYL
                     SRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA"
     gene            14226..14939
                     /locus_tag="VXB91_001422"
     CDS             14226..14939
                     /locus_tag="VXB91_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HEV0470859.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGFLKELEDFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQKLFDATLDNPELTATLVPLG
                     DGILMLRKNVADVQLSESE"
     gene            15006..15947
                     /gene="prsA"
                     /locus_tag="VXB91_001423"
     CDS             15006..15947
                     /gene="prsA"
                     /locus_tag="VXB91_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HEV0470860.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFY
                     EQVKNNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
     gene            complement(16064..16405)
                     /locus_tag="VXB91_001424"
                     /pseudo
     CDS             complement(16064..16405)
                     /locus_tag="VXB91_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT         4946 a         3083 c         3676 g         4736 t
ORIGIN      
        1 caaatctggt ggctacatgg cgaaaaatga gacagtagat ggttatcagc ttggaagcga
       61 tggtaaatgg cttggaggaa aaactacaaa tgaaaatgct gcttactatc aagtagtgcc
      121 tgttacagcc aatgtttatg attcagatgg tgaaaagctt tcctatatat cgcaaggtag
      181 tgtcgtatgg ctagataagg atagaaaaag tgatgacaag cgcttggcta ttactatttc
      241 tggtttgtca ggctatatga aaacagaaga tttacaagcg ctagatgcta gtaaggactt
      301 tatcccttat tatgagagtg atggccaccg tttttatcac tatgtggctc agaatgctag
      361 tatcccagta gcttctcatc tttctgatat ggaagtaggc aagaaatatt attcggcaga
      421 tggcctgcat tttgatggtt ttaagcttga gaatcccttc cttttcaaag atttaacaga
      481 ggctacaaac tacagtgctg aagaattgga taaggtattt agtttgctaa acattaacaa
      541 tagccttttg gagaacaagg gcgctacttt taaggaagcc gaagaacatt accatatcaa
      601 tgccctttat ctccttgccc atagtgccct agaaagtaac tggggaagaa gtaaaattgc
      661 caaagataag aataatttct ttggcattac agcctatgat acgacccctt acctttctgc
      721 taagacattt gatgatgtgg ataagggaat tttaggtgca accaagtgga ttaaggaaaa
      781 ttatatcgat aggggaagaa ctttccttgg aaacaaggct tctggtatga atgtggaata
      841 tgcttcagac ccttattggg gcgaaaaaat tgctagtgtg atgatgaaaa tcaatgagaa
      901 gctaggtggc aaagattagt actataagtg aatatgattt gagtgaatag taagttaaaa
      961 atcctgattt caagtaaaat caggattttt tcatggatgc aatttttttg gagtctggtg
     1021 tgacgcggag ggtcttttgt cctgtgtaag tgacaaagcc gggttttcca ccagttggtt
     1081 tattgagttt tttgacttca atcatatcta cctgcaccag attcgacagg cgcccttgag
     1141 agaagtaggc agctaactct gctgcgtctg tcttgactgc atcagatggg tcaagatttc
     1201 ctgagatgac aacatggctt ccaggaatgt ccttagcatg gaaccaaagt tcctccttgc
     1261 gggccatttt aaaggtcaat tcctcatttt gaagattgtt tcgtccgaca tagatgatgg
     1321 ttttgccatc gcttgctaga tattgttcta gttttttgcg tttctggatt ttctcccgtt
     1381 gtcttctgcg gataaaacct gtttgaatca attcttcacg gatttcagcg atttcttcca
     1441 gtccagcttg gttgaggacg gtttctacac tttccagata gagaatagtg gctttggttt
     1501 cttcaatcaa atcagtcaag tatttgacag cttctttgag tttctgatac cgtttaaaat
     1561 agcgttgggc attctggttg ggagtcagag ccttatcaag cccaatcatg ataggttggt
     1621 tggtatagta gttgtctagg ataacctggt cttggtcgtt aggcacttgg tggaggaagg
     1681 ttgtcagcaa ttctcctttt tgacgaaatt cttcagcgtt gtctgtcgcc agtaattctt
     1741 tttcctgttt tttgagtttg tgtcggtttt tctgaagttc attttcaaca cgacgaatca
     1801 gttcactggc ctgctgtttg acgcggtcgc gctcagcctt atccttatag taggtgtcca
     1861 acaaatcaga aagatttgca aaaggctctc ccacctgatt tgcaaaagga actggactga
     1921 aggaagtctc agtcaagcat ggcttggttt cctgattgaa aaaatttcgg aaagcggaaa
     1981 gtttttcact aaccagtatc ctttccaatt catttgccgt atcgcgtccc agaccttgaa
     2041 agaggctttg aagatttttt gctgttagtt cttgggtttg caggatttca aagagctttt
     2101 catccttgat agtaaaagga ttgagagatt ctgtacttgg cggagcgata taggtcgatc
     2161 ctggaagtaa ggtgcggtag ctattttgtg aaaagccgac gtgtttgata acttcgagga
     2221 ttttatgact gcttttatcg accagtagaa tattactgtg tttccccata atttcgataa
     2281 tcaaggtagc ctggatatgg tctccaatct cgtttttatt ggaaactgtc atttccacaa
     2341 tacggtcatt ttccacttgc tcaatcgact caatcagggc cccctgcaaa tactttctca
     2401 aaaccatgat aaaggtagaa ggttgggctg gattttcaaa agtcgtttgg gtcagctgaa
     2461 tgcgtccaaa aactggatgg gcagaaagga gcaggcgatg gctttggcga ttgctgcgga
     2521 tttgcaagac caactcttgt tcaaaaggct gattgatttt ctggatgcga ccattcacta
     2581 attcgcttcg caattcctca actatgtggt gtaaaaaaaa tccgtcaaat gacatcgttc
     2641 tctccttgtg attgtattcc atagtattat atcaaaaagg tagaataaaa tcatggaaat
     2701 gtggtataat aaagccaagt aaagagaaac gagaagcaca tgtatattga aatggtagat
     2761 gaaactggtc aagtttcaaa agaaatgttg caacaaaccc aagaaatttt ggaatttgca
     2821 gccaaaaaat taggaaaaga agacaaggag atggcagtca cttttgtgac caatgagcgt
     2881 agtcataaac ttaatctgga gtaccgtgac accgaccgtc cgacagatgt catcagcctt
     2941 gagtataaac cagaattgga aattgccttt gacgaagagg atttgcttga aaatccagaa
     3001 ttggcagaga tgatgtctga gtttgatgcc tatattgggg aattgttcat ctctatcgat
     3061 aaggctcatg agcaggccga agaatatggt cacagctttg agcgtgagat gggcttcttg
     3121 gcagtacacg gctttttaca tattaacggc tatgatcact atactccgga agaagaagcg
     3181 gagatgttcg gtttacaaga agaaattttg acagcctatg gactcacaag acaataaacg
     3241 aaaatggaaa aatcgtgacc tgatatccag tttagaattt gccatcacag ggatttttac
     3301 tgctatcaag gaagaacgca atatgcgaaa acatgcagtg acggctctag tggtcatcct
     3361 tgcaggtttt ggttttcagg tgtcacgaat cgaatggctc tttctcctat tgagcatttt
     3421 cttggtggta gcctttgaaa ttatcaattc tgctattgaa aatgtggtgg atttggccag
     3481 tcactatcac ttttccatgc tggctaaaaa tgccaaggat atggcggctg gcgcggtatt
     3541 agtggtttct ctttttgcag ccttaacagg cgcattgatt tttctcccac gaatctggga
     3601 tttattattt taaacagtaa gaggaaatta tgacttttaa atcaggcttt gtagccattt
     3661 taggacgtcc caatgttggg aagtcaacct ttttaaatca cgttatgggg caaaagattg
     3721 ccatcatgag tgacaaggcg cagacaacgc gcaataaaat catgggaatt tacacgactg
     3781 ataaggagca aattgtcttt atcgacacac cagggattca caaacctaaa acagctctcg
     3841 gagatttcat ggttgagtct gcctacagta cccttcgcga agtggacact gttcttttca
     3901 tggtgcctgc tgatgaagcg cgtggtaagg gggacgatat gattatcgag cgtctcaagg
     3961 ctgccaaggt tcctgtgatt ttggtggtga ataaaatcga taaggtccat ccagaccagc
     4021 tcttgtctca gattgatgac ttccgtaatc aaatggactt taaggaaatt gttccaatct
     4081 cagcccttca gggaaataac gtgtctcgtc tagtggatat tttgagtgaa aatctggatg
     4141 aaggtttcca atatttcccg tctgatcaaa tcacagacca tccagaacgt ttcttggttt
     4201 cagaaatggt tcgcgagaaa gtcttgcact taactcgtga agagattccg cattctgtag
     4261 cagtagttgt tgactctatg aaacgagacg aagagacaga caaggttcac atccgtgcaa
     4321 ccatcatggt cgagcgcgat agccaaaaag ggattatcat cggtaaaggt ggcgctatgc
     4381 ttaagaaaat cggtagcatg gcccgtcgtg atatcgaact catgctagga gacaaggtct
     4441 tcctagaaac ctgggtcaag gtcaagaaaa actggcgcga taaaaagcta gatttggctg
     4501 actttggcta taatgaaaga gaatactaag tagaggtagg ctcatgcctg cttcttgttt
     4561 ttacagaagg aggacttatg cctgaattac ctgaggttga aaccgtttgt cgtggcttag
     4621 aaaaattgat tataggaaag aagatttcga gtatagaaat tcgctacccc aagatgatta
     4681 agacggattt ggaagagttt caaagggaat tgcctagtca gattatcgag tcaatgggac
     4741 gtcgtggaaa atatttgctt ttttatctga cagacaaggt cttgatttcc catttgcgga
     4801 tggagggcaa gtatttttac tatccagacc aaggacctga acgcaagcat gcccatgttt
     4861 tctttcattt tgaagatggt ggcacgcttg tttatgagga tgttcgcaag tttggaacca
     4921 tggaactctt ggtgcctgac cttttagacg cctactttat ttctaaaaaa ttaggtcctg
     4981 aaccaagcga acaagacttt gatttacagg tctttcaatc tgcccttgcc aagtccaaaa
     5041 agcctatcaa atcccatctc ctagaccaga ccttggtagc tggacttggc aatatctatg
     5101 tggatgaggt tctctggcga gctcaggttc atccagctag accttcccag actttgacag
     5161 cagaagaagc gactgccatt catgaccaga ccattgctgt tttgggccag gctgttgaaa
     5221 aaggtggctc caccattcgg acttatacca atgcctttgg ggaagatgga agcatgcagg
     5281 actttcatca ggtctatgat aagactggtc aagaatgtgt acgctgtggt accatcattg
     5341 agaaaattca actaggtgga cgtggaaccc acttttgtcc aaactgtcaa aggagggact
     5401 gatgggaaaa atcatcggaa tcactggggg aattgcctca ggtaagtcaa ctgtgacaaa
     5461 ttttctaaga cagcaaggct ttcaagcagt ggatgccgac gcagtcgtcc accaactaca
     5521 gaaacctggt ggtcgtctgt ttgaggctct agtacagcac tttgggcaag aaatcattct
     5581 tgaaaacgga gaactcaatc gccctctcct agctagtctc atcttttcaa atcctgaaga
     5641 gcaaaaatgg tctaatcaaa ttcaagggga gattatccgt gaggaactgg ctactttgag
     5701 agaacagttg gctcagacag aagagatttt cttcatggat attcccctac tttttgagca
     5761 ggactacagc gattggtttg ctgagacttg gttggtctat gtggaccgag atgcccaagt
     5821 agaacgctta atgaaaaggg accagttgtc caaagatgaa gctgagtctc gtctggcagc
     5881 ccagtggcct ttagaaaaaa agaaagattt ggccagccag gttcttgata ataatggcaa
     5941 tcagaaccag cttcttaatc aagtgcatat ccttcttgag ggaggtaggc aagatgacag
     6001 agattaactg gaaggataat ctgcgtattg cctggtttgg taattttctg acaggagcca
     6061 gtatttcttt ggttgtacct tttatgccca tcttcgtgga aaatctaggt gtagggagtc
     6121 agcaagtcgc tttttatgca ggcttagcaa tttctgtctc tgctatttcc gcggcgctct
     6181 tttctcctat ttggggtatt cttgctgaca aatacggccg aaaacccatg atgattcggg
     6241 caggtcttgc tatgactatc actatgggag gcttggcctt tgtcccaaat atctattggt
     6301 taatctttct tcgtttacta aacggtgtat ttgcaggttt tgttcctaat gcaacggcac
     6361 tgatagccag tcaggttcca aaggagaaat caggctctgc cttaggtact ttgtctacag
     6421 gcgtagttgc aggtactcta actggtccct ttattggtgg ctttattgca gaattatttg
     6481 gcattcgtac agttttctta ctggttggta gttttctatt tttagctgct attttgacta
     6541 tttgctttat caaggaagat tttcaaccag tagccaagga aaaggctatt ccaacaaagg
     6601 aattatttac ctcggttaaa tatccctatc ttttgctcaa tctcttttta accagttttg
     6661 tcatccaatt ttcagctcaa tcgatcggcc ctattttggc tctttatgta cgcgacttag
     6721 ggcagacaga gaatcttctt tttgtctctg gtttgattgt gtccagtatg ggcttttcca
     6781 gtatgatgag tgcaggagtc atgggcaagc taggtgacaa ggtgggcaat catcgtctct
     6841 tggttgtcgc ccagttttat tcagtcatca tctatctcct ctgtgccaat gcctctagcc
     6901 cccttcaact aggactctat cgtttcctct ttggcttggg aaccggtgcc ttgattcccg
     6961 gggttaatgc cctactcagc aaaatgactc ccaaagccgg catttcgagg gtctttgcct
     7021 ttaatcaggt attcttttat ctgggaggtg ttgttggtcc catggcaggt tctgcagtag
     7081 caggtcaatt tggctaccat gctgtctttt atgcgacaag cctttgtgtt gcctttagtt
     7141 gtctctttaa cctgattcaa tttcgaacat tattaaaagt aaaggaaatc tagtgcgagt
     7201 aaaaattaat ctcaaatgct cctcttgtga cagtatcaat tacctaacca gtaaaaattc
     7261 aaaaacccat ccagacaaga ttgaggtttt aaagtattgt cccaaggaaa gaaaagtaac
     7321 cctacatctt gaatctaagt agattttatg gtaaaataat agggatttta aggagtttga
     7381 tatgtataac ctattattaa ccattttatt agtattatct gttgtgattg tgattgcaat
     7441 tttcatgcaa ccaaccaaaa accaatccag caatgtattt gatgccagtt caggtgattt
     7501 gtttgaacgc agtaaagctc gcggttttga agctgtaatg cagcgtttga cagggatttt
     7561 agtctttttc tggctagcca ttgccttagc attgacggta ttatcaagta gataagaaaa
     7621 taatgggcag gactaggtct ttgcctcttt ttatttttaa aggatgtttg agaaggtttt
     7681 acagtaaaag aaaattaaaa aatctagaaa gaaaatatga aagatagaat aaaagaatat
     7741 ttacaagaca agggaaaggt gactgttaat gatttggctc aggctttggg aaaagacagt
     7801 tccaaggatt ttcgtgagtt gattaaaacc ttgtccttaa tggaaagaaa gcaccagatt
     7861 cgctttgaag aagatggtag tctgacatta gaaattaaga aaaaacatga gattaccctc
     7921 aaggggattt ttcatgccca taaaaatggc tttggctttg ttagtctgga aggcgaggag
     7981 gacgaccttt ttgtagggaa aaatgatgtc aactatgcta ttgatggtga taccgtcgag
     8041 gtagtgatta agaaagtcgc tgaccgcaat aagggaacag cagcagaagc caaaattatt
     8101 gatatcctag aacacagttt gacaacagtt gtcgggcaaa tcgttctgga tcaggaaaag
     8161 cctaagtatg ctggctatat tcgttcaaaa aatcataaaa tcagtcaacc gatttatgtt
     8221 aagaaaccag ccctaaaatt agaaggaaca gaagttctca aagtctttat cgataaatac
     8281 ccaagcaaga aacatgattt ctttgtcgct agtgtactcg atgtagtggg acactcaacg
     8341 gatgtcggaa ttgatgttct tgaggtcttg gaatcaatgg acattgtatc tgagtttcca
     8401 gaagctgttg tcaaggaagc agaaagtgtg cctgatgctc cgtctcaaaa ggatatggaa
     8461 ggtcgtctgg atctaagaga tgaaattacc tttaccattg acggtgcgga tgccaaggac
     8521 ttagacgatg cagtgcatat caaggctctg aaaaatggca atctggagct tggggttcac
     8581 atcgcagatg tttcctatta tgtgaccgag gggtctgccc ttgacaagga agcccttaac
     8641 cgtgcgactt ctgtttacgt gacagaccga gtggtgccaa tgcttccaga acgactatca
     8701 aatggcatct gctctctcaa tccccaagtt gaccgcctga cccagtctgc tattatggag
     8761 attgataaac atggtcgtgt ggtcaactat accattacac aaacagttat caagaccagt
     8821 tttcgtatga cctatagcga tgtcaatgat atcctagctg gcgatgaaga aaagagaaaa
     8881 gaatatcata aaattgtacc aagtatcgaa ctcatggcca agcttcatga aactttagaa
     8941 aacatgcgtg tgaaacgtgg agctctcaat tttgatacca atgaagcgaa gattttagtg
     9001 gataaacaag gtaagcctgt tgatatcgtt cttcggcagc gtggcattgc cgagcggatg
     9061 attgagtctt ttatgttgat ggctaatgaa acagttgccg aacatttcag caagttggat
     9121 ttgcctttta tctatcgaat tcacgaggag cctaaggctg aaaaggttca gaagtttatt
     9181 gattatgctt cgagttttgg cttgcgcatt tatgggactg ccagtgagat tagtcaggag
     9241 gcacttcaag acatcatgcg tgctgttgag ggagaacctt atgtagatgt attgtccacg
     9301 atgcttcttc gctctatgca gcaggctcgt tattcggagc acaatcacgg ccactatgga
     9361 ctagctgctg actattatac tcactttacc agtccaattc gtcgttatcc agaccttctt
     9421 gttcaccgta tgattcggga ttacggctgt tctaaggaaa tagcagagca ttttgaacaa
     9481 gtgattccag agattgcgac ccagtcttcc aaccgtgaac gtcgtgccat agaagctgag
     9541 cgtgaagtcg aagccatgaa aaaggctgag tatatggaag aatacgtggg tgaagagtat
     9601 gatgcagttg tatcaagtat tgtcaaattc ggtctctttg tcgaattgcc aaacacagtt
     9661 gaaggcttga ttcacatcac taatctacct gaattttatc atttcaatga gcgtgatttg
     9721 actcttcgtg gagaaaaatc aggtatcact ttccgagtgg gtcagcagat ccgtatccgt
     9781 gttgaaagag cggataaaat gactggagag attgattttt cattcgtacc tagtgagttt
     9841 gatgtgattg aaaaaggctt gaaacagtct agtcgtagtg gcagagggcg tggttcaaat
     9901 cgtcgttcgg ataagaagga agacaagaga aaatcaggac gctcaaatga taagcgtaag
     9961 cattcacaaa aagacaagaa gaaaaaagga aagaaacctt tttacaagga agtagctaag
    10021 aaaggagcca agcatggcaa agggcgaggg aaaggtcgtc gcacaaaata aaaaggcacg
    10081 ccacgactat acaatcgtag atacgctaga ggcagggatg gtcctgactg gaactgaaat
    10141 caagagtgta cgagctgctc gaattaatct caaggatggc tttgctcaag tgaaaaatgg
    10201 agaagtttgg ctgagcaatg ttcatatcgc gccttacgaa gagggcaata tctggaacca
    10261 ggaaccagaa cgtcgtcgta aactcctgct ccataaaaag caaattcaaa aattggaaca
    10321 agagaccaaa gggacaggaa tgaccttagt tccccttaag gtctatataa aagatggcta
    10381 cgctaagctt cttttaggac ttgccaaagg gaagcatgac tatgacaaac gggagtctat
    10441 caaacgtcgt gagcaaaatc gagatatcgc gcgtgtgatg aaagctgtta atcagcgata
    10501 aaaagaggaa ttgaaaatgg aaaaattagt tgcctataaa cgcatgcctt tgtggaataa
    10561 acaaacaatg cctgaagctg ttcagcaaaa gcacaataca aaagttggga cttgggggaa
    10621 aattactgtc ttgaagggag ctctcaagtt tattgaattg acagaagaag gggaagttct
    10681 agctgaacac ctctttgaag caggggcaga caatccaatg gcccaacctc aagcctggca
    10741 ccgagtggaa gctgccacag atgatgtgga atggtacttg gaattttatt gtaaacctga
    10801 ggattatttt gctaaaaaat acaataccaa tcctgttcat tcagaggtcc tagaggccat
    10861 gcagacagtg aaacaaggga aagctttgga tttgggttgt ggtcaggggc gtaattctct
    10921 ttttctagcc cagcaagatt ttgatgtgac ggctgtagat caaaatggac tagctcttga
    10981 aatcttgcaa agcattgtgg agcaggaaga tttggacatg cctgttggcc tttacgatat
    11041 caattcagct agcattgaac aagaatatga ttttatcgtt tcaacagttg ttctcatgtt
    11101 tctacaagcg gaccgcattc cagctattat tcaaaatatg caggagaaaa ccagtgttgg
    11161 cggttacaac cttatcgttt gtgccatgga cacggaggat tatccttgct cggttaactt
    11221 cccattcacc tttaaagaag gagaactggc agactattac aaggattggg aattggttaa
    11281 gtacaatgaa aatccaggcc atttgcaccg tcgcgatgag aatggcaatc gtattcaact
    11341 acgctttgcg accttactag ctaagaaaat caagtaaaca cacatgaaga ttaggaattt
    11401 tcctgatctt ttttcttttt tacgaatgat atagaaaagg agggaattca tgtttgttgc
    11461 gagagatgct aggggagaat tggtaaatgt gttagaggat aaacttgaga agcaagcata
    11521 cacctgccca gcttgtggag gccagctcca tttgcgtcaa ggaccaagtg tacggacgca
    11581 ttttgcccat aaatccttaa aagactgtga ttttttcttt gaaaatgaaa gtccagaaca
    11641 cctggccaat aaggaatccc tctatcactg gttgaaaaaa gagacaaagg ttcaattaga
    11701 gtacccgctt tcagaactta aacagattgc ggatgtattt gtaaatggca atctagctct
    11761 agaagttcag tgtagtccct tgcctcagaa agtccttaaa gagcgaagtg agggctatcg
    11821 tagtcagggt taccaagtac tgtggttgct gggtcaaaaa ctgtggctca aggagcgttt
    11881 gactcgtcta cagcaaggtt ttctttattt cagtcaaaac atgggctttt atgtttggga
    11941 attagacaag gaaaaacaag ttttaagact caaatacctg atttaccagg atctccgcgg
    12001 taaactccat tatcaaatca aggaattttc ctatggtcaa ggtagtttat tggaaatatt
    12061 gcgtcttccc tataagagac aaaaaatatc tcattttaca gtttctgagg acaaggacat
    12121 ctgtcgctat atccggcaac aactttatta tcaaaatctc ttttggatga aagaacaagc
    12181 agaagcctat caaaagggag aaaatatcct gacttatgga ctgaaagaat ggtatccaca
    12241 aattcgacca atagtgggca aatttttcca gattgaacaa gacttgacta gctattatca
    12301 gcacttttat acctattacc aaaaaaatcc tcaaaatgat tggcaaaagc tttatccacc
    12361 agccttttat cagcaatatt tcttgaaaaa tatggtagaa tagaaaggat ggaggaatct
    12421 aatggtatta caaagaaatg aaataaatga aaaagataca tgggatctat caacgatcta
    12481 cccaactgac caggcttggg aagaagcctt aaaagattta acagaacaat tggagacagt
    12541 agcccagtat gaaggccatc tcttggatag tgcggataac ctactagaaa tcactgaatt
    12601 ttctcttgaa atggaacgcc agatagagaa gctttacgtt tatgctcata tgaagaatga
    12661 ccaggataca cgtgaagcta agtatcaaga gtactatgcc aaggccatga cactctacag
    12721 ccagttagac caagcctttt cattctatga gcctgaattt atggagatta gcgaaaagca
    12781 gtatgctgac tttttagaag ctcaaccaaa gctgcaggtt tatcaacact attttgacaa
    12841 gctcttgcaa ggcaaggatc acgttctttc acaacgtgaa gaagaattat tggctggagc
    12901 tggagaaatc tttggttcag caagtgaaac cttcgctatc ttggacaatg cggatattgt
    12961 gttcccttat gtcctagacg atgatggtaa agaagttcag ctatctcatg ggacttacac
    13021 acgtttgatg gagtctaaaa aacgtgaggt tcgccgtggt gcctatcaag ctctttatgc
    13081 tacttacgaa caattccaac acacctatgc caaaaccttg caaaccaatg ttaaggtgca
    13141 aaattaccgt gctaaagttc gtaactacaa gagtgctcgt catgcagccc tcgcagcgaa
    13201 ttttgttcca gaaagtgttt atgacaattt ggtagcagca gttcgcaagc atttgccact
    13261 cttacatcgc tatcttgagc ttcgttcaaa aatcttgggg atttcagatc tcaagatgta
    13321 cgatgtctac acaccgcttt catctgttga atacagtttt acctaccaag aagccttgaa
    13381 aaaagcagaa gatgctttgg cagtcttggg tgaggattac ttgagccgtg ttaaacgtgc
    13441 cttcagcgag cgttggattg atgtttacga aaatcaaggc aagcgttcag gtgcctactc
    13501 tggtggttct tacgatacca atgcctttat gcttctcaac tggcaggaca atctggacaa
    13561 tctctttact cttgttcatg aaacaggtca cagtatgcat tcaagctata ctcgtgaaac
    13621 tcagccttat gtttacgggg attactctat ctttttggct gagattgcct caactaccaa
    13681 tgaaaatatc ttgacggaga aattattgga agaagtggaa gacgacgcaa cacgctttgc
    13741 tattctcaat aacttcctag atggtttccg tggaacagtt ttccgccaaa ctcaatttgc
    13801 tgagtttgaa cacgccattc accaagcaga tcaaaatggg gaggtcttga caagcgattt
    13861 cctaaataaa ctctacgcag acttgaacca agagtattat ggtttgagta aggaagacaa
    13921 tcctgaaatc caatacgagt gggctcgcat tccacacttc tactataact actatgtata
    13981 tcaatattca actggctttg cggccgcctc agccttggct gaaaaaattg tccatggtag
    14041 tcaagaagac cgtgaccgct atatcgacta cctcaaggca ggtaagtcgg actatccact
    14101 taatgtcatg agaaaagctg gtgttgatat ggagaaggaa gactacctca acgatgcctt
    14161 tgcagtcttt gaacgccgtt taaatgagtt tgaagccctt gttgaaaaat taggattggc
    14221 ataaaatggt tgaatcgtat agtaagaatg ctaaccataa catgcgtcgt cctgtcgtca
    14281 aagaagaaat tgtagacttg atgcgtcagc gtcaaaagca ggtcacaggt ttcttgaaag
    14341 aattggaaga ctttgcccgc aaggaaaata ttcctattat tccccatgaa acggttgctt
    14401 atttccgttt tcttatggaa accatgcagc ctaaaaatat tctggaaatt gggacggcta
    14461 tcggtttttc agctctcttg atggctgaac atgcgccaaa tgctaagatt acaactattg
    14521 atcgtaatcc agaaatgatt ggttttgcca aggaaaattt tgcccagttt gacagtcgca
    14581 agcaaatcac tctcctagag ggagatgcgg tggatgtctt atctacactg acagagtctt
    14641 atgatttcgt atttatggat tctgccaagt ctaaatacat cgtctttctg ccagaaatcc
    14701 tcaaacattt ggaagttggt ggtgtggttg tcttggatga tatttttcaa ggtggtgatg
    14761 ttgccaagga tattatggaa gtccgtcgtg gtcagcgaac catttatcga ggccttcaaa
    14821 aattatttga tgcaacctta gacaatccag aactcaccgc aacattagtg cctttaggag
    14881 atggtattct catgcttcgt aaaaatgtag cagatgttca actgtctgaa agcgaatgat
    14941 tttcagaaaa atttaagaaa aaatagtaaa atagatagag taacacttat ctcaaaggag
    15001 tagacatgaa gaaaaaatta ttggcaggtg ccatcacact attatcagta gcaactttag
    15061 cagcttgttc gaaagggtca gaaggagcag accttatcag catgaaaggg gatgtcatca
    15121 cagaacatca attttatgag caagtgaaaa acaacccttc agcccaacaa gtcttgttaa
    15181 atatgaccat ccaaaaagtt tttgaaaaac aatatggctc agagcttgat gataaagagg
    15241 ttgatgatac tattgccgaa gaaaaaaaac aatatggcga aaactaccaa cgtgtcttgt
    15301 cacaagcagg tatgactctt gaaacacgta aagctcaaat tcgtacaagt aaattagttg
    15361 agttggcagt taagaaggta gcagaagctg aattgacaga tgaagcctat aagaaagcct
    15421 ttgatgagta cactccagat gtaacggctc aaatcatccg tcttaataat gaagataagg
    15481 ccaaagaagt tctcgaaaaa gccaaggcag aaggtgctga ttttgctcaa ttagccaaag
    15541 ataattcaac tgatgaaaaa acaaaagaaa atggtggaga aattaccttt gattctgctt
    15601 caacagaagt acctgagcaa gtcaaaaaag ccgctttcgc tttagatgtg gatggtgttt
    15661 ctgatgtgat tacagcaact ggcacacaag cctacagtag ccaatattac attgtaaaac
    15721 tcactaagaa aacagaaaaa tcatctaata ttgatgacta caaagaaaaa ttaaaaactg
    15781 ttatcttgac tcaaaaacaa aatgattcaa catttgttca aagcattatc ggaaaagaat
    15841 tgcaagcagc caatatcaag gttaaggacc aagccttcca aaatatcttt acccaatata
    15901 tcggtggtgg agattcaagc tcaagcagta gtacatcaaa cgaatagtcc aaatcaatga
    15961 gtcagggaaa aaactctact tcaggaaaaa atgaagcaaa cattcccaca ataaaacgcg
    16021 tagtacaagg tttgtactga cccccaaaag ttagacaaat aatttatccg aaggatttag
    16081 ttctgtattg cacagggcta agtcctttta gttttacctt aattctcttg ttgttgtaat
    16141 aatcaatata gtctataatg gcttgttcca attgattaag tgatttaaat gttttctcat
    16201 agccataaaa catttcggat tttaaaatac caaagaaaga ttccatccta ccgttgtctt
    16261 ggctgtttcc cttgcgtgac atagatgctt gaattccctt actctctagg aaccgatgat
    16321 aagaatcgtg ttggtattgc cagtcttggt cactatggag aatcgtattc tcgtagtgct
    16381 tctctttgaa tgcctgttcc aacattaacg atcaatcaat ttaatcatgt acctaatatt
    16441 a
//
LOCUS       DAVLBE010000039        15384 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.039, whole genome shotgun sequence.
ACCESSION   DAVLBE010000039 DAVLBE010000000
VERSION     DAVLBE010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15384)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15384)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15384
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.039"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(370..1977)
                     /locus_tag="VXB91_001425"
     CDS             complement(370..1977)
                     /locus_tag="VXB91_001425"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HEV0470861.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAAAMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDTEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENSN"
     gene            complement(2367..2954)
                     /locus_tag="VXB91_001426"
     CDS             complement(2367..2954)
                     /locus_tag="VXB91_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HEV0470862.1"
                     /translation="MELEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            complement(3082..3531)
                     /locus_tag="VXB91_001427"
     CDS             complement(3082..3531)
                     /locus_tag="VXB91_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0470863.1"
                     /translation="MCFVPYYKVNHCEEAFAWYQDVNLVYLVDGVKLPYSQATLEAMY
                     SYLDRHGELFWIEVKEKGEWFPIGDITLSQDNLPIVIGNSAYQHRGLGKKILSALIEL
                     ARVKGWKELRVKEIYTYNHASRRCFKSLGFVENGATEKGRSFILELV"
     gene            complement(3536..3925)
                     /locus_tag="VXB91_001428"
     CDS             complement(3536..3925)
                     /locus_tag="VXB91_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partitioning protein ParB"
                     /protein_id="HEV0470864.1"
                     /translation="MKVNIADLHPTQLYLSEKKLQDIQMLYQSAETIQVDPISILAFG
                     DCLLITDGHHRAYQTLLADRDTISAEWDRDGGDELYHLYAQACEERKIYSVFDLEDRI
                     LAQDGYEAKWYNWCDGFNQAATLLLKR"
     gene            complement(3953..4579)
                     /locus_tag="VXB91_001429"
     CDS             complement(3953..4579)
                     /locus_tag="VXB91_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEV0470865.1"
                     /translation="MKGSFALLLFVILGYMVKFYPETLVNFDQSIQTAIRGDLPDYLT
                     ILFRALTRLIDIPVIITWVVITAFVFYRKRWKIESFFMLGNLALAGLLIVTFKNIYQR
                     PRPDILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKDPVWRKIVQIVLGLYLVS
                     VLVSRVYLGVHYPSDVLASLCVGLGVLFIEFPFYDKLRFQWRFKGKQK"
     gene            complement(4593..5156)
                     /locus_tag="VXB91_001430"
     CDS             complement(4593..5156)
                     /locus_tag="VXB91_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV0470866.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTIGLTLAMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYVLLKPTLKHYER"
     regulatory      complement(5321..5555)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(5609..6112)
                     /locus_tag="VXB91_001431"
     CDS             complement(5609..6112)
                     /locus_tag="VXB91_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HEV0470867.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFISQMKGKLYLISKFAEKIYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     gene            complement(6305..7135)
                     /locus_tag="VXB91_001432"
     CDS             complement(6305..7135)
                     /locus_tag="VXB91_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEV0470868.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRMLL
                     LIAIFSVFLLYLSEIRFKDVSFVAVFATVFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGVYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVVSLLLILQNQGRFYNPWK
                     "
     gene            complement(7120..8802)
                     /locus_tag="VXB91_001433"
     CDS             complement(7120..8802)
                     /locus_tag="VXB91_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0470869.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQVAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLPLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHRPVDRIV
                     LISDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLANLDNMSIS
                     KGQVQLQNELAKETPELQSLFKLEDVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKAISSFIQTEGRYLWEKQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEKEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHQKGHTIVMITHDMQLMLDYSDRVLVMVDGELIA
                     DTVPASLLSDPELLVKANLKETSIFNLAKKLDVDPLDLTAFYKERREGCKLN"
     gene            complement(8904..9161)
                     /locus_tag="VXB91_001434"
     CDS             complement(8904..9161)
                     /locus_tag="VXB91_001434"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0470870.1"
                     /translation="MKIKEQTRKLAAGCSKQCFEIVDRTDEVSSKHGFEVVDETDEVS
                     NHTYGKAKLTWFEEIFEEYKMMGKAGQLVFFDVYRLVRQVS"
     gene            complement(9168..9716)
                     /locus_tag="VXB91_001435"
     CDS             complement(9168..9716)
                     /locus_tag="VXB91_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HEV0470871.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLAGYGLWWTWIIASGLFGLVVGLFRKYVRVING
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
     gene            complement(9731..10579)
                     /locus_tag="VXB91_001436"
     CDS             complement(9731..10579)
                     /locus_tag="VXB91_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HEV0470872.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     EQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            10767..12116
                     /gene="trkA"
                     /locus_tag="VXB91_001437"
     CDS             10767..12116
                     /gene="trkA"
                     /locus_tag="VXB91_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HEV0470873.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVSRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKGVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            12120..13559
                     /locus_tag="VXB91_001438"
     CDS             12120..13559
                     /locus_tag="VXB91_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEV0470874.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSLIDAF
                     FEISSGFTTTGASILNDISVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYIALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRVKAFFGDEELRAYL
                     VIVLVSTGLISLNTLYLYPGFSKSFEMTFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMAIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNKMVIDKDTQHK
                     ILKYFVIYAMILLALIFIVSLDSNDFLVVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(13684..13941)
                     /locus_tag="VXB91_001439"
     CDS             complement(13684..13941)
                     /locus_tag="VXB91_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HEV0470875.1"
                     /translation="MNEGAQLAEVRVIANSGAYGAHYDIMGVYDLIILAPQVRSYYRE
                     MKVDAERLGIQIVATRGMEYIHLTKNPSKALQFVLEHYQAV"
     gene            14701..14871
                     /locus_tag="VXB91_001440"
     CDS             14701..14871
                     /locus_tag="VXB91_001440"
                     /inference="COORDINATES: protein motif:HMM:NF024172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0470876.1"
                     /translation="MTKQVPKFTKDTAQLYTCKWLLYNKVTKMYDHTVVNHSVREYIT
                     DSISTNTIEETG"
BASE COUNT         4623 a         3432 c         2773 g         4556 t
ORIGIN      
        1 attttactat agtggattaa attaaaaaag tataatgtat tgaatctata acagtacatc
       61 ttgactgcta aaatatttct ataaattaat ttgactttcc ttatagagat gttcacatct
      121 tatttcaatt catgatacaa tccagttcct aaaactttgc tagaaattaa tttggctttc
      181 cgaattaatt tgttcagatt ttatttcatt tcaatatact gataaatcca ttcactagca
      241 cagggcaaga gggagtcgct attgatttca acggtagcag gtacatacag aggactccta
      301 cctcagatat actgcaatat catcgtatgc aaaaaacctc tgagattttt ctcaaaggtt
      361 ctgattttgc taattgctgt tctcaaccgc tgcagtaaca aaggcagtgt agagttcttc
      421 tggtcggttt ggacggcttg acagttcagg gtgatactga caagctacaa agaatttatt
      481 ttcaggaatt tccacgattt ctaccaaacg attgtctgga gaaactcctg aaaagacaaa
      541 acctgctgcc tcaaactgct cacggaaggc attattaaac tcataacggt gacggtgacg
      601 gcgttgcacc acttcttgat tgtgataagc agcagcagcc ttagagccac gtttcaactt
      661 agacggataa agtcccaaac gaagggttcc acccatatcc tcaatatcaa tctgatcacg
      721 catgatatca atgatagggt attttgtttc tggtgcaagc tctgcagaat tggcaccttc
      781 aagacctaaa acgtgacgag caaactcgat acatgtcaac tgcattccca agcagactcc
      841 caacattgga acatcatttt cacgcgcata gcggatggct tggattttcc cttctgtacc
      901 acgttgacca aaaccacctg gtacgatgat cccgtccgca tcagacaaga gttctgctac
      961 attctctgct gtcacatcat tggcattgac ccaattgatt ttaacttctg tatcattgac
     1021 atagccagag tgtttcaagg cttcgaccac tgagatatag gcatcttgca actccacata
     1081 cttaccaaca agggaaatct taacttgttt cttgaggttc atgaccttgt ccaccatggc
     1141 tgaccattct gtcatagccg ctgctggtgc gtctaatttc aaatgatcac aaacaatttg
     1201 gtccatccct tgtgcctgca agttcagtgg aatttggtaa aggtgttcaa catccaacga
     1261 ttcgataacg gcttctggtg ccacatcaca gaactgggcc agtttatttt taattccttg
     1321 accagctggc tcttctgtac gaataaccaa catatttggt tggattccca agccacgcaa
     1381 ttctttgaca gagtgttggg ttggtttggt tttcatttca ccagcagcct tgaggtaagg
     1441 aagcaaggtt gtatggatat acatgacatt atccgcaccc acatctgcct tcatctgacg
     1501 aagagcctct aggaatggca aggactcgat atctcctact gttccaccaa cctctgtgat
     1561 aatgacatca gagtcggtcg ttagagcggc acgcttgatt ttttctttca aagcatctgt
     1621 gatatgagga atgacttgaa cagttgcccc aaggtattct ccacggcgtt ctttacgaag
     1681 aacttcactg taaattttcc cagttgtcac gttggaatat ttgttgagat tgatatcgat
     1741 aaaacgttca tagtgaccca agtccaaatc tgtctcagct ccgtcatctg tcacaaaaac
     1801 ttccccgtgc tggtaaggac tcatggttcc cggatcaata ttgatataag ggtcaaactt
     1861 ttgaatggtt actttgagac cacgattttt caagagacgg cctagactcg ctgccacaat
     1921 ccctttccca atagacgata ccacaccacc agttacaaaa atatatttcg tagacataga
     1981 ttcctctttc taaaatgctc aaggtcttgt taactacgag gggatataga aaacaagacc
     2041 ctactaataa gaataatctg ggacgactgc accagattca caactaatac tcttcgaaaa
     2101 tctcttcaaa ccgcgtcaac gtcgccttgc cgtagatatg tgttcctgac tttgtcagtc
     2161 ttatctacaa cctcaaaaca gtgttttgag cagcctacgg ctagtttcct agcttgctct
     2221 ttgattttca ttgagtataa aatacaagaa gataacttct tgaaaaaaca aaaatagctc
     2281 cctaagaact agggagcccc gacctctaaa agaggtgccc aaacaatatg atacctaaaa
     2341 ataggataat tgtcaatagc taactcttat tcctcgctgg tttcagcgtc gtcatctgaa
     2401 aactcgtcgt cgtcttcgtt gagatccaca tcttctccca agtcatctgg agcgatttcg
     2461 ttgatttctg catcataagc ttccacttca tttttttcat catctggatt ttcatcatcg
     2521 tatgaaagag ctggatctgc ttcgtatgca tcttcgtctt ctggatcatc tgcattgtag
     2581 tcaatggcat ctgaatcacc atccataaag gcattgacac gttttttctt agcttttggt
     2641 gctacttcat cgtcgtcatt ttcttcaaga gcgatgattt cttcgtcgat ttcgtccaca
     2701 ccataccatg aacgaagacc ccatttgttg tccccaagtg agatgaagct accgtcaaag
     2761 ttcaactctg tgtagaacag aggcaaagct tcgcggatat cgctgtttga tgttccaagg
     2821 tagttttgaa tttcgtttac aagatcgcta aaatgcatct catgatcgcg accacgaagt
     2881 tctaatatag cacgcgctac ctcaatcata gatagttcac ttttttcttg cccagcaaat
     2941 acttctaatt ccaaagcgtt tctcctcatt tatactacta tcgccagagc gaacagactc
     3001 tgacctcatt ttatcattta ctctttattt tacgataatt ttgcggaata gtcaaaggtt
     3061 aagggggaga aagtggcagg attagactaa ttccaatata aaactccttc ctttttctgt
     3121 tgctccattt tccacaaatc caagcgactt gaaacacctc ctagaagcat gattgtaggt
     3181 gtagatttcc ttgactctca attctttcca tccttttact cgagccaatt caatcaaagc
     3241 acttagaatc ttttttccaa gtcctcgatg ttggtaagcg gaattcccaa tcacaatggg
     3301 gagattatcc tgagatagtg taatatcccc aattggaaac cattctccct tctccttgac
     3361 ttcaatccaa aaaagctcac catgccgatc caaataggaa tacatggctt ccaaggtcgc
     3421 ttgactgtaa ggaagcttca ccccatctac gaggtaaacc aagttcacat cctgatacca
     3481 agcaaaagct tcctcacaat gattgacctt ataataagga acaaaacaca atgcactacc
     3541 ttttcaacaa aagagttgct gcttgattaa aaccatcaca ccagttatac cattttgctt
     3601 catacccatc ttgagctagg atacgatctt ctaaatcaaa aacagagtaa atctttcttt
     3661 cctcgcaagc ttgcgcatag agatgatata gttcatcacc accatctcta tcccactcag
     3721 cagaaatcgt atcccgatct gccaataaag tctgataagc cctgtgatgc ccatctgtaa
     3781 tcagcaaaca atctccaaag gcaagaatac tgattggatc gacttggatt gtttctgccg
     3841 actggtaaag catctgaata tcttgcaact tcttttctga taaatatagt tgagtcggat
     3901 gaagatctgc tatgttgact ttcatttctt tctcctcaag ggaattcgat actcacttct
     3961 gtttgccttt aaatcgccat tggaagcgga gcttgtcata gaagggaaac tcgataaaca
     4021 ggactcccaa gcccacacag agactggcaa ggacgtctga tgggtaatga actcccagat
     4081 agactcttga taccagcaca ctgactaggt agaggccaag gacgatttgt acgatttttc
     4141 tccagactgg atctttaatc cgctgactaa gaataacaat caaagtacct accatcaagg
     4201 ttacagccag agaatgccca cttgggaagg aaaatccctt ctcctccacc agatgtaaga
     4261 tatctggccg tgggcgctgg tagatatttt taaaggtcac gattaaaaga cctgccaaag
     4321 ccagatttcc cagcatgaag aaactttcta tcttccatcg cttacgataa aagacaaaag
     4381 ctgtaatgac aacccaagtg ataatcactg ggatatcaat cagacgtgtg agggctcgaa
     4441 aaagaatagt caaataatct ggtaagtctc ctcgaatggc agtctgaatc gattggtcaa
     4501 aattgaccag cgtttcaggg taaaatttga ccatgtagcc aagaataacg aaaagtaaaa
     4561 gggcaaaact gcccttcatt aaaaatgttt gtttatctct cataatgttt taaggttggt
     4621 ttcaagagaa catacaacaa ccagaatgaa acggaaaaga taacaccttc aatcaagtta
     4681 aaaggtaata ccatggtcat taggtagttg gaaagtccca aaatttttcc aatatcaaag
     4741 ttagcaaact tagcgtacaa aggaacagca taaacatagt tgagaaccaa catggccaag
     4801 gttaaaccaa tagttccagc tagagagcct agtaggaaac gaagggttgt ccgttccttt
     4861 ttccaaatca aagcaaatac gatgacaaaa actcccaaag ctacgatatt catcggcaaa
     4921 ccaatgtaag tattcactcc ttggctgtta agaagcaact tcaagagtga gcgaagcaag
     4981 agcactccta gagcagcagg caaatccatg accaccagac ccacaaggac tggcaagata
     5041 ctaaattcga tcttgaggaa agatgccgct ggtaaaagcg gaaaatcaaa gtacatcagc
     5101 acaaatgaga tggctgatag aattgcaatg gtcgaaagtc gacgtgtgtt tgtcataaca
     5161 ggttcctcca attttctata aaatcagaag aagttggaaa ggattcctct atctattctc
     5221 actttttata tcccaaaagt tccctcttac tctattaaag aaaaacaaag caagtggtta
     5281 caatccggct ataaatctat caaaacagac aaagctattc tttcgtcttc tcccatccag
     5341 actatactgt cggttgtgga atctcaccac atcagcttgc gctcgcggac ttctttaaag
     5401 ggaaagaaat agagattttt cttttagact aggcgacaag ctgtaggcat aacttctggt
     5461 taggcaaagc ttgtcaacaa agtataaaag gaaaagatca tttcctagtt aaagtcaccg
     5521 ccggtcggga atcacaccct gccctgaaga ctcttttatc ataacaaaaa acgcttgcaa
     5581 gcgcaagcat tttgttcatt ttcatttttt atttcaattt atccacttca taggtatgga
     5641 cgagctcaag acctgcaaag ttctgctggc gaagagcctc atagacaatc atgcagacgg
     5701 tattagacac attgagactg cggacatgtt catcattcat gggaatacgg agagccttct
     5761 caggatgttc tcgcataaaa tcttcaggta agcccttgtc ttcacgtcca aagagaaaat
     5821 aatggtcctc gtcagtcgat aaatccacct cagaatagat tttttccgcg aatttcgaaa
     5881 tcagatagag ttttcccttc atctgagata tgaaatcttc taaactctcg taaaaataaa
     5941 tctctagctt atcccagtaa tccaatccag cccgcttcat cttgcggtca tcaataggaa
     6001 agcccatagg cttgatgatg tggaggggag aattggtcgc agcgcaagta cgcgcgatat
     6061 tgcctgtatt ttgtggaatt tgaggttcaa ataatacaat gtgatttgtc atgacttgct
     6121 tcctttcacc attgcaaaaa aatagccaca ctgcccggag tcaagctcag caaacagcgt
     6181 ggttaaggca tcgttaactt acctcacaac aggtttgaag taaatcagcg aaactacttt
     6241 cttagtataa cactttcaga atcattgtca atagaaatga cttgattttt tcaatttttt
     6301 caagctattt ccaagggttg taaaatcgtc cctgattctg caagataagt agtaaactaa
     6361 ctactaaaaa caaggttgcc aagagcaagg taatatagtc tccttttttc aaggcctgat
     6421 aactatacca tgtgcgtttt ttctctttcc caaagcggcg aagctccatg gcagtcgcaa
     6481 tggtatcaat gcgttctagc gagctaaaaa tcaagggcgt aataatgagc agattgcctt
     6541 tgattcgttg cataagagaa gctttcttgg ataattccat cccacgcgcc tcctgagaca
     6601 tcttgatagt aaagaattct tcctgcaaat ctggaatata gcgcaaggtc aggctgacag
     6661 aataagcaat cttatagggc acaccaattt gatttaaact ggaagcaaac tgactaggat
     6721 gggttgtcat caaaaagata atagccagag gaatggtgca aagatactta atggccaaat
     6781 ttagcagata aaagagctcc tggctggtta gagtgtagac accgattccc tgccaaatca
     6841 cacttctctc tccataaagt ccaaccccat actcgggaga aaagagatag accatcaaaa
     6901 cgtttaaaac ggcaaatacc gtcgcaaaaa cggctacaaa ggaaacatct ttaaagcgaa
     6961 tttctgataa atagaggaga aagactgaaa agatggcaat cagcaagagc attctggtat
     7021 catagctaat catggccgcc aatgatacca gaatgaaaaa gagaagtttc ccagctcctg
     7081 acaagcgatg aatcacagta tctctatgct ggtaaccgat taatttagct tgcatccctc
     7141 tctcctttct ttgtaaaatg ccgttaaatc cagtggatcc acatctagtt tcttagccaa
     7201 gttaaagatg gaggtttctt ttagattggc ttttactaac agctcaggat cgctcaacag
     7261 actggctgga acagtatcgg caatcaattc tccatccacc atgacaagga cccggtctga
     7321 ataatccagc atcaattgca tatcatgggt aatcatgaca atggtatgcc ctttttgatg
     7381 taactcttcg agaaattcca taatctcagt atagttcttc tgatcttgac ctgcagtcgg
     7441 ttcatctagg agaataattt cagctcctaa gaccaaaatt gaagcaatgg tgacacgttt
     7501 tttctgacca aatgacaggg cagaaatagg ccaattacgg aattcataaa gtccacagat
     7561 tttcaaggtt tcatagactc tcgtttcaat ttccttctca tccacacctc gcaaacggag
     7621 ccctagagcc acctcatcaa aaatcatatt ggttgaaatc atttgattag gattttgtag
     7681 cacatagcct actcgttccg cccgctctgc aacagaatcg ccttttatat cctgtttttc
     7741 ccaaagatag cgtccttccg tctgaataaa gctacttata gccttggcta gagttgattt
     7801 ccctgctcca ttttttccga caatagcaat cttttcaccc tttttaatat ctaaatgtag
     7861 ggattttaaa atcggtctat catcataaga gaaagacacg tcctctaatt taaagagtga
     7921 ctgcaattct ggagtttctt ttgccagttc attctgcagc tgaacctgac cttttgagat
     7981 agacatgtta tccagattcg ctaactgttc ttccttgact aagtccacac ctaattgacg
     8041 gagagtcgtt agataaaggg gttctcgaat tccattttga gtcaataaat cagtcgcaag
     8101 caactggtca gggctcccat taaaaaggat acgaccatcg cttatcaaga caatccgatc
     8161 cacagggcga tgcagaacat cctccaaacg gtgctcgata atcagagtcg tcgtcccctc
     8221 ttccttatga atctggtcaa tcaattcgat aatatcctga cctgacttgg gatctagatt
     8281 ggcgagtggc tcatcaaaca agagaatcgg actttcatca atcaagacac cagccagact
     8341 gactcgctgc ttttgtccac ctgacaaatc ctgaggacgc tgatccagta aaggaagaag
     8401 gtccagcttt tcagcccatt tataaacacg acctttcatc tcatctaggg ctgtcacatc
     8461 attttccaga gcaaacgcca aatcttctgc cacagacaag ccaataaact gcccatctgt
     8521 atcctgcaaa actgtgctaa ccagatgaga cttatcatag atgctcatat caaaggctac
     8581 ttgacccttt atcaaaaatt ctccatatgt ctgacccttg taaatattgg gaataatccc
     8641 attcaaacac tgacccaagg tagatttacc tgacccagat ggtccaacaa ttaagacttt
     8701 ctctcccttg taaatggtca agtctatccc ttgcaaggtc ggttcttgtt gtgtttcata
     8761 ccggaaagag aaatccttcc actcaattat agcttctttc atcttactct cttcattcgc
     8821 ttcttagact tctattttat cataaatcaa gcccttcttg cagtctcttc tcttaaaatc
     8881 ttagcgccaa aaagattcct atcctagctt acttgcctaa ctaatctata aacatcgaaa
     8941 aagactagtt gcccagcctt ccccatcatt ttatactctt cgaaaatctc ttcaaaccac
     9001 gtcagcttcg ccttgccgta ggtatggtta ctgacttcgt cagtttcatc tacaacctca
     9061 aaaccatgtt ttgagctgac ttcgtcagtt ctatccacaa tctcaaaaca ctgttttgag
     9121 caacctgcgg ctaacttcct agtttgctct ttgattttca ttgagtatta gtcctttttc
     9181 aaacttcctg cacgagtttg ggttcctgca taggcaagta agagaagagt tcctgcaata
     9241 gctacagata caccattggc aattcccgca acaatccctt gtgcaaatac tttttctgcc
     9301 gcttcttgat aaatcacaac atctccaagt ggtgccaaga caccccaaac aagggcattt
     9361 gcaagtagtt gaatgaggtt aaaaataaga atatctttcc agtcaaaaac accattgatc
     9421 actcgaacgt actttctaaa aagtcccaca actagaccaa agagtccgct agcgataatc
     9481 caagtccacc atagaccata accagcaaga gagtccttga ttgcatgacc aatcaacccg
     9541 acaagcaaac cgataatcgg tccaaaaata atagaaagta gcgcttgtac cgcatactga
     9601 agctggatgc ttgtatttgg aacaggggtt ggaatgttga tcatcccgat gacgacaaag
     9661 agggcagcgc caattccgac agcaacaact tgtttaattg taaatttgat ttccatacta
     9721 ttctcctatt ttatccttct attttcttta tttcaatggt ccaagatgaa ccgacaccta
     9781 cattataggc cttggcaaag gaaccttggt tgatagccaa acctaaacga tagagagagt
     9841 tgatgtaaag gatgggttgc ccaattctca catctgcaaa tgatttgcca tagacaacct
     9901 gattttgata gaccagcata tcagcatgat agatggtcac ttcaaaacga tcaccaaatt
     9961 ctggttccag cttgtaaaat tcttcccgtg tgatagaggt ccaaagcgaa ccgaaacgca
    10021 catccagaat atcaatggct cccttcacca gatgatcttc tatgatggtc gctacgactg
    10081 gaagctctac aatctgttcc acactgagct ctggccctac ttcctcaaaa gtaatgtgac
    10141 cactggccag tttagcacca gtataggcat agacatcacg accgtggaag gtataagaat
    10201 gctctgtgtt ttgacgccta ttggccacct cagaaatctc acgaatggct acaatgccaa
    10261 cgtgtttctt gataaaggaa agcgtcccat tatctggcgt gacaatgtat tgattttttg
    10321 cagtcttggc aactacactc ttacgtttcg aaccgacacc tggatcgaca accgatacaa
    10381 acgtcgttcc ctcaggccag taatccaccg tctgaaagag acgatagctc ccctcaaaaa
    10441 tattataagg cgtgatatcg tgcgtcaagt gatggatttt taaggttgga gactcttcta
    10501 aagccactcc aatcatagcc gacaccgcac catcaaccag accaaagtct gattgtaata
    10561 ccagtaaatt attgttcatt ttatctcctt gtatatcctt tatcatacca tatttcagag
    10621 aaagtcgcta atagctattt caattggtta gggtatagtt ttaccttata gcgaattttc
    10681 actaaaagct cttgttatta gctagtaggt gcattttttc ttgaaaaagg gtatgatagt
    10741 tacatcatga aaaagtaggt tttattatga aaattatcct tgtcggaggg ggaaaagttg
    10801 gttttgccct ctgtcgctcc ttggttgcag aaaagcatga tgttttgctg attgagcaag
    10861 acgaagctgt tctcaatcat attgtcagtc gctttgatat cattggtatc cttggtaacg
    10921 gggccgattt tgccattctt gagcaagcca gcgtccaaga ttgtgatatc tttatcgccc
    10981 tgactgagca cgatgaagtc aacatgattg cagcagttct agccaagaaa atgggagcta
    11041 aagaaactat cgttcgggtg cggaaccctg aatattctaa ctcttatttc aaggaaaaga
    11101 atattctcgg tttttctctt atcgttaatc ctgagctctt ggctgcccgc gctatcgcga
    11161 atatcattga cttccccaac gccctgtctg tcgaacgctt tgctggtgga cgcgttagcc
    11221 tcatggaatt tgtcgtcaag tccaccagcg gtctttgcca aatgcccatt tctgattttc
    11281 gtaaaaaatt tggtaatgtc attgtctgtg cgatagagag ggatcatcaa attatcattc
    11341 caagcggtga catgactgta caggataaag atagaatctt tgtcactggt aaccgtgtcg
    11401 atatgatact cttccataat tattttaaat cacgcgccgt gaagagcctt ctcatcgttg
    11461 gagcaggtag aattgcctat tatctacttg gtattctcaa agatagtcgt atcgatacaa
    11521 aagtcattga aatcaatcct gaaatcgcca gcttctttag cgagaaattc ccaaatctct
    11581 acatcgttca aggagatgga accgcaaaag atatcctgct ggaagaaagt gctcaacact
    11641 atgatgccgt tgcgactcta acaggagtcg atgaggaaaa tctgattaca tctatgttcc
    11701 ttgacagggt aggtgtacag aaaaatatta ctaaggtcaa tcgtaccagt ctcctcgaga
    11761 ttatcaatgc gcctgatttt tcaagtatca tcacacctaa aagcatcgct gtagatacga
    11821 ttatgcactt tattcgtggt cgagttaatg cccagtattc agaccttcaa gccatgcacc
    11881 atctagccaa tggccaaatc gaaaccctgc aattccatat caaggaagcc aataaaatga
    11941 ctgccaaacc tctttctcaa ctgaaattga aaaaaggggt tcttattgca gccattattc
    12001 gaaagggcaa gactattttc ccaactgggg aggatatgtt ggaagttgga gacaagctcc
    12061 tagtaacaac cttgttgcca aacatcacca agatttatga cttgattgcg aggtaagaaa
    12121 tgaataaaag tatgattcgt tacctccttt caaagttact tttgattgaa gctgttctcc
    12181 tcttggttcc tgtggctatc gctgtctatt accgtgaatc gagccaagtc tttacagccc
    12241 tcttttcgac catagggatt ctcgtattgt taggcggttc agggagttta cagaagccaa
    12301 aaaatcaacg gatttatgcc aaggagggag tcttgatcgt tgccctctgt tggatccttt
    12361 ggtctttctt tggtggtctc ccctttgtct tttctgggca aatccctagc cttattgatg
    12421 ccttttttga aattagttct gggtttacaa ctactggagc aagtattttg aacgacattt
    12481 cggttctcag ccgttccctc ctcttctggc gaagttttac ccacttgatt ggagggatgg
    12541 gagtgcttgt ttttgcactt gctattatgg acaatgccaa aaatagtcac ctagaagtaa
    12601 tgaaggctga ggttcctggt cctgtctttg gtaaggttgt atccaaatta aaaaacactg
    12661 cccagatcct ctatctcctt tacatagccc tcttttccct ctttgtcatc atctattatc
    12721 tagccggtat gcctctctac gatagttttg tcattgctat ggggacagcg ggaactggag
    12781 gatttaccgt ctataacgat ggaattgccc actatggtag ctcactgatt acctatctgg
    12841 ttagtatagg agttttggtt tttggggtaa atttcaatct ctactactac cttatgctcc
    12901 gtcgggttaa ggccttcttt ggagatgaag agcttcgggc ttacttggtc atcgtgctgg
    12961 tttctacagg cttgattagc ctcaatactc tctacctcta cccagggttt tcaaagagct
    13021 ttgaaatgac cttcttccag gtttccaaca tcattacaac aactggtttt ggatatggag
    13081 atattaccaa ctggcccctc ttctcccagt ttatcctcct tttcctcatg gcaatcggtg
    13141 gctctgctgg atcaactgca ggtggactca agattattcg aggcctcatc ctttcaaaaa
    13201 ttgccaaaaa ccaaattttg tcaatcctat cgccccaccg tgttttgacc ctccatgtta
    13261 ataaaatggt gattgacaaa gatacccagc ataagattct caagtacttt gtcatctatg
    13321 ctatgatttt gctagcgctt atctttattg tcagcctaga tagcaatgat tttctggtcg
    13381 tgaccagcgc tgtctttagc tgtttcaata atatcgggcc tattctagga accacttcta
    13441 gtttctcaat ctttagtccc atctcaaaaa ttctcctctc ctttgcaatg attgcagggc
    13501 gcttggagat ttacccaatc ctccttctct ttatgaaaag aacttggtct aagagataaa
    13561 atacaaaatc cctcttttta caattgtgaa agagggattt ttatattaaa aagggggaac
    13621 gtttttaaat ccaagcctgt ctgtaagcaa agttcttact caaataaaag atggaaaaac
    13681 ttactacaca gcttggtaat gctccaatac aaattgtaag gctttacttg gattctttgt
    13741 taaatgaata tattccattc ctctggtagc aactatctga atacctaatc tttctgcatc
    13801 caccttcatc tctctataat aactccgaac ttgtggagcc agaataatta aatcataaac
    13861 acccataata tcataatgag ctccgtacgc tcctgaattc gcaatcactc taacttctgc
    13921 taattgagcg ccctcgttaa ttgcattggc taattacgca cttgttccag accctgcaca
    13981 aagaaccagt actttcaact ccttactttt tattacatct atctcaccag gcattatttc
    14041 acttgtatcc tcctctaaaa taatatcatt tgagcttgca atatctacaa cctgtagtag
    14101 atatctcgta tttagacaat atgaaaacaa gacgacttcc atataggaaa ccgccttctc
    14161 tctatgttga gtgatttata ttaaaataac ttttcttcta gctgcatttt attattataa
    14221 aaacattcat cataaccctg aacttaaata acgattttta ttcaagatac atactcctag
    14281 aataaacttt atatgaaatt ctcatttttg tttttacaat tctccttagt taaatcttgt
    14341 ttaatatatg ttttacatat agtatttagc gccacatagt actgaactct ctccaaaaac
    14401 ggttattcct ctttgaatag ggcgttatca caagaaaagc atctccacgt ttcaacttca
    14461 tatggctcaa aaacaatcaa ttgatgctaa aacctgtacc tagatgtttc ggttcataaa
    14521 accatgaaac tgtaaaagtg aatgaaattg atagcgatag tcaaatcaag aggcatcata
    14581 actctaaaaa gtcacaatat ataagttcat cctcggaaaa atatcattct aattgttgaa
    14641 atgcctacat gaaaagaaac gtcaaatgct catgaaacaa cgaatacagg tatcaaaact
    14701 atgacaaaac aagtccctaa atttactaaa gacactgctc aactttacac ctgtaagtgg
    14761 ttgttgtata ataaagttac aaagatgtac gaccacactg ttgtaaatca tagtgttcgc
    14821 gaatatatta ctgatagcat ttctacaaat acaattgaag agactggata gactttaaac
    14881 gaaatatgtc agtgttttgg cattcctagc cttcatatca tttaaagaat tctatagaca
    14941 aaatttttcc caatacagac actcgtaaca actgcttcat ttttctacca acatatttag
    15001 gaacaggata agatacaaga ggattaatcc atagatcagt tctataccaa tctaagacaa
    15061 ataagctaaa aaaacgattg ataataagca aatagattcc aaattttctc tatctgctca
    15121 ttttaataaa caatactagt gtaactatcc ttccagtcag aaacttgtca aatcacaccg
    15181 aaaactcttc taaaatttat ctcgttaggc aatcaagcaa aaactcgacg atagtacaaa
    15241 cattatcata cagaattgac tgcctaaatt atatacttta gtaaggtttt cggataagaa
    15301 aaaaggttca ttttacattt ctaaacattc ttttctaaga tgaaaaacag aatttttcga
    15361 ttgtgattta aagcaacaag aaga
//
LOCUS       DAVLBE010000040        15322 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.040, whole genome shotgun sequence.
ACCESSION   DAVLBE010000040 DAVLBE010000000
VERSION     DAVLBE010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15322)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15322)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15322
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.040"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            167..466
                     /locus_tag="VXB91_001441"
                     /pseudo
     CDS             167..466
                     /locus_tag="VXB91_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
     gene            549..2570
                     /locus_tag="VXB91_001442"
                     /pseudo
     CDS             549..2570
                     /locus_tag="VXB91_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
     gene            2572..3213
                     /locus_tag="VXB91_001443"
     CDS             2572..3213
                     /locus_tag="VXB91_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0470877.1"
                     /translation="MIELKNISKKFGSRQLFSDTNLHFEGGKIYALIGTSGCGKTTLL
                     NMIGRLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLNLGLV
                     GKKLKEKEKISLMKQALNCVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTASLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            3317..4669
                     /locus_tag="VXB91_001444"
     CDS             3317..4669
                     /locus_tag="VXB91_001444"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HEV0470878.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQCLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYSNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIASD
                     KDTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGLFEEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLVKDLASKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPG
                     SHNVENALATIAVAKLRDVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            4673..5731
                     /locus_tag="VXB91_001445"
     CDS             4673..5731
                     /locus_tag="VXB91_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HEV0470879.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVGWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLSKVEHVGA
                     VTKVSDQKNPEPDELVDIQTHFNHKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELSQNLFRVDYVTDLYQPLLELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQIENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            5741..6940
                     /gene="divIB"
                     /locus_tag="VXB91_001446"
     CDS             5741..6940
                     /gene="divIB"
                     /locus_tag="VXB91_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HEV0470880.1"
                     /translation="MSKDKKNEDKEILEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQEDSESAKEESEEKVASSEDDKEKEEKEEPES
                     KEKEEQDKKLAKKATKEKPAKAKIPGIHILRAFTILFPSLLLLIVSAYLLSPYATMKD
                     IRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQFPTK
                     FTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIKVFV
                     SELAQISPELKAAIQKVELAPSKVTSDLIRLTMNDLDEVLVPLSEMSKKLPYYSKIKP
                     QLSEPSVIDMEAGIYSYTVADKLIMEAEEKAKQEAKEAEKKQEEEQKKQEEESNRNQT
                     TQRSSRR"
     gene            7173..7874
                     /gene="pyrF"
                     /locus_tag="VXB91_001447"
     CDS             7173..7874
                     /gene="pyrF"
                     /locus_tag="VXB91_001447"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HEV0470881.1"
                     /translation="MREHRPVIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKVLSQLGVDMTNVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QVIKQATNPDFICLTPGIRPAGAAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPV
                     AAYHTIKDEWTQDWN"
     gene            7908..8540
                     /locus_tag="VXB91_001448"
     CDS             7908..8540
                     /locus_tag="VXB91_001448"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HEV0470882.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVEAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYSELIHLAQEEGYITPEGLDLLKRFKEDQENWQEG"
     gene            8720..9123
                     /locus_tag="VXB91_001449"
                     /pseudo
     CDS             8720..9123
                     /locus_tag="VXB91_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829085.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            9219..9983
                     /locus_tag="VXB91_001450"
     CDS             9219..9983
                     /locus_tag="VXB91_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0470883.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKKYLAIVG
                     STVIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQFLYSLVTTLW
                     YGVWGAVFSIFGLASALLVKKKIGAIFIPVAYMMVGGIFWAILGLSYLEPVTTLALGY
                     QKDISLSLVSGHLAFILFVSCLVVYGTFFLHSEDYV"
     gene            9983..10735
                     /locus_tag="VXB91_001451"
     CDS             9983..10735
                     /locus_tag="VXB91_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0470884.1"
                     /translation="MKQFVQFYKKDFLSVLVYFILLLSCVLSSTVYLLRCRQYSIHPN
                     VLEWILVLLQDMTTGVYCFPFTYILFFFYLMNNYFNRLECRIRLKSIKHFTSFSFKLA
                     ALSTGIWTATLFLLIFLIAFSNGFSFSLEIKEVDFLREFYGISIANNASFFIGFFFSY
                     IAYYFFLSLLTISSFSWFKKSNMSLVFLFTFLFVESLFWIYQLDNGIIGLLPIFQYMV
                     NSNPYALIYWLTLLSIIIPLTVFSVHRNWRRV"
     gene            10745..11443
                     /locus_tag="VXB91_001452"
     CDS             10745..11443
                     /locus_tag="VXB91_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0470885.1"
                     /translation="MGKLSSHMWRLNQIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAVVYRRRASDFFMEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLPNWDIGVLFIVDSLNACVLVLFCFMLYALG
                     ANVQMNFACVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDIGRDLFLQLLFLVFLFK
                     SIFYFTRQKRRFIE"
     gene            11440..12087
                     /locus_tag="VXB91_001453"
     CDS             11440..12087
                     /locus_tag="VXB91_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0470886.1"
                     /translation="MNEIIILKNIELKLKKTCVFQNLNFSCKQGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRKLSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(12167..13028)
                     /locus_tag="VXB91_001454"
                     /pseudo
     CDS             complement(12167..13028)
                     /locus_tag="VXB91_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765255.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine ABC transporter substrate-binding
                     protein"
     gene            complement(13040..13798)
                     /locus_tag="VXB91_001455"
     CDS             complement(13040..13798)
                     /locus_tag="VXB91_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV0470887.1"
                     /translation="MSETILEIKELKKSFGDNPILQGLSLEIKKGEVVVILGPSGCGK
                     STLLRCLNGLESIQGGDIFLDGQSIVENKKNFHLVRQKIGMVFQSYELFPHLDVLQNL
                     ILGPIKTQGRDKKEVTEEALQLLDRVGLLDKQHSFARQLSGGQKQRVAIVRALLMHPE
                     IILFDEVTASLDPEMVREVLELINDLAQEGRTMILVTHEMQFAQAIADRIIFLDQGKI
                     AEEGTAQAFFTNPQTKRAQEFLNVFDFSQFGSYL"
     gene            complement(13799..14476)
                     /locus_tag="VXB91_001456"
     CDS             complement(13799..14476)
                     /locus_tag="VXB91_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001154125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV0470888.1"
                     /translation="MQDSGIQVLFQGNNLLRILQGLGVTIGISILSVLLSMMFGTVMG
                     IIMTSHSRIIRFLTRLYLEFIRIMPQLVLLFIVYFGLARNFNINISGETSAIIVFTLW
                     GTAEMGDLVRGAITSLPKHQFESGQALGLTNVQLYYHIIIPQVLRRLLPQAINLVTRM
                     IKTTSLVVLIGVVEVTKVGQQIIDSNRLTIPTASFWIYGTILVLYFAVCYPISKLSTH
                     LEKHWRN"
     gene            complement(14436..15104)
                     /locus_tag="VXB91_001457"
     CDS             complement(14436..15104)
                     /locus_tag="VXB91_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006531263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV0470889.1"
                     /translation="MVEQYLPLYQKAFFLTLHIAVWGILGSFLLGLIVSIIRHYRILV
                     LSQVATAYIELSRNTPLLIQLFFLYFGLPRIGIVLSSEVCATLGLVFLGDSYMAESFR
                     SGLEAISQTQQEIGLAIGLTPLQVFYYVVLPQATAVALPSFSANVIFLIKETSVFSAV
                     ALADLMYVAKDLIGLYYETDIALAMLVVAYLIMLLPISLVFSWIERRLRHAGFGNPST
                     LSRK"
BASE COUNT         4616 a         2637 c         3312 g         4757 t
ORIGIN      
        1 agaggtaata tagtaaaata tctaaaaaat tcgatttttt ccttgacaac aaataataaa
       61 aatgttattc ttatcacata agaaagcggt ttcaataaaa gagagaggag gatttatttt
      121 gttgcattgt tgctcaaggt gtgatttttt tgaaagaaaa aataaaatga aaacgaaaaa
      181 acatagatta cttgctctag ctcttatttc aagttttaca ttattgggag ctgcatcagc
      241 tgctgtataa tatccagatg gaggagtatg gacatatgga gaaggttcag gaggtggtta
      301 ggctttttca aattactatc atggtaaaaa atatcattat tcatccatcg tgagcagatg
      361 ggatggtcat tctgataaag gagaagctcc tgctggaaaa acctcctatg catggatttg
      421 gactaaatgg ggagaacaag tagcatttta ctgtgattat gactaatcgt tcattgattt
      481 aaatcgttcc ccttgtaaga aattacaggg ggaattttgt ttacaaggag tctaccaagg
      541 agtctactat gaagaaacta ttcatattat tatcaacttt ttttctcagc ttcttccttg
      601 cttggattat tgtcttacgt gcgccacaat atttatatgc aagctatgat tccgtttctt
      661 tacttcgtgt caaaaaagat actcaggaac cgacgcgtga ggtatttgaa caggaattgg
      721 agaattttgc aaactcagaa cagagtttaa tagctagaag aattgtagag ccgagtaagg
      781 atgggacgac tcactttact tatgcaactt atggtcaggg aactttacca aaagaattcc
      841 aagaagctag ccaagaaagt cgtgaacgta gtgatccgct aaatagttat ctccttttgt
      901 caggctcctt gacgaaagaa aagcttgccg ataaattagg agatttgggt tataaagcaa
      961 gtgctgaccg aaagataccg ccctattttc ttgcttttcg aatattacta aatcccctta
     1021 ttttaattag tttagcaata tttggcttat ctttctttgc tttagtgatt atcactcgga
     1081 ttaaggaaat gagagcagca ggtataaaac tcttttctgg tcagactctc ttatccatca
     1141 tggggcattc tttatctact gatatcaaat agctccttct atcagccctc ctttccttcc
     1201 taggtggggg agtcgttctt tttagtcaag gtttgtttta tcctatcttg ttagccacct
     1261 atggttttgg gattagtttc tatctgttgt ttttattggc gatttcaatt ttactaatgc
     1321 ttctttatct aatgagtttg agttacaaag cattagttcc cgttattaag gggagattac
     1381 cccttaaacg cctgatgatt ttaaccctat tgtgtcagtt ggttgctgtc tttacagtag
     1441 gatacgctgt taagacaggt ttgacgtctt accaacgatt gaaagaactt gaaatttcaa
     1501 aacaagcatg gcaggataga gcagactatt atcaaatttc ttttggctta ggtgatagag
     1561 gaaaagatac agaaaatcag agcaagtggt atgcctttgc caaggaagca atcgaagagg
     1621 aacaagctct ttatgtaaag gataatctgc tccattttgc caatccacaa ggaaaaaatg
     1681 aacagggaga gacactggat acctatagtc cagatgctaa tacgctctat gttagtccca
     1741 gttatttgga caaggaaaag gtcgtggtag atgctgagac caaacagaag ttagcccatc
     1801 tccaaaaagg tgagtttatc ctcttgctcc cagaacattt gcgctctcga gaagcagaac
     1861 ttaagaaagt ttttgaagaa agattgagtt attatggaaa atctggtgag gaggcaagtg
     1921 ctcctttgga ttatgagatg aaagcgcacg ttagttatct ttcaatggga gaaaagcggt
     1981 ttgtttataa taacggtgag aatcccgtat ctactcagta tttgactgat ccgattttag
     2041 tggtattcac gccgacttct acaggtgata gttttatatc cttatctagt tggtctatca
     2101 atgctggaaa acaactcttt atcaaaggat atgagagtgg gctagaactc ttgaagaaag
     2161 ctggaattta tgagcaagta tcctatctta aagaaggaag aagtgtttat ctaactcgtt
     2221 ataatgaagt tcaaactgaa acagcaactt taatcttagg agctattgtg gggatagcta
     2281 gttccttatt actattttat tctgtcaatc ttctatattt cgagcaattc cgccgagata
     2341 tcttgattaa acgaatttca ggtttacgat tttttgaaac acatgctcag tatatggtta
     2401 gccaatttgc cagttttgta tttggtgcta gtctctttat tttaagcagt cgagacttgg
     2461 tgattggctt gctcacttta ttggtctttc tagctagtgc agttttgacg ctttaccgtc
     2521 aagcgcagaa agaatctcgt gtttctatga caattatgaa aggaaaatag gatgattgaa
     2581 ctaaagaata tatctaaaaa atttggaagc cgtcagctat tttcagatac gaatcttcat
     2641 tttgaaggtg ggaaaattta tgccttaatc ggtacaagtg gctgtggtaa gacaacactc
     2701 ttgaatatga ttggacgatt ggagccatat gacaaagggc aaatcatcta tgatggcact
     2761 tctcttaagg acatcaagcc ttctgttttc tttagagatt acttaggata cttatttcaa
     2821 gattttggct taattgaaag ccaaaccgtc aaagagaatc tcaatctggg tttagttggt
     2881 aaaaagttga aggaaaaaga gaaaatctct ttgatgaaac aagctctaaa ctgtgtaaac
     2941 ctctcttatt tggatttgaa gcaacctata tttgagttat caggaggaga agcacaacgt
     3001 gttgcactag cgaagataat tttaaaggat ccgcctttga ttcttgcaga tgaaccaacc
     3061 gcttccttag accccaaaaa ttctgaggaa ttactttcca tcctagaatc tttaaaaaat
     3121 ccgaatcgga ccattattat tgcgacccac aatcctctga tttgggagca agtggatcag
     3181 gtcattcgag ttaccgattt atcacataga tgatatggta agattcagtt agaagaaaga
     3241 gtcacaaaca cactttgtgg cttttttatt tccataaaaa tggtaaaata gtaggagtag
     3301 aaatggagtt cgagacatga aagtaataga tcaatttaaa aataagaaag ttcttgtttt
     3361 aggtttggcc aagtctggtg aatctgcggc tcgtttgttg gacaagttag gtgccattgt
     3421 gacagtaaat gatgggaaac cattcgagga caatccagct gcccaatgtt tgctggaaga
     3481 agggatcaag gtcattacag gtggccatcc tttggaactc ttggatgaag agtttgccct
     3541 catggtaaaa aatccaggta tcccctacag caatcccatg attgaaaagg ctttggccaa
     3601 gggaattcca gtcttgactg aggtggaatt ggcttatttg atttcagaag caccgattat
     3661 tggtatcaca ggatcgaacg gtaagacaac cacaacgact atgattgggg aagttttgac
     3721 tgctgctggg caacatggtc ttttatcagg gaatatcggc tatcctgcca gtcaggttgc
     3781 tcaaatagca tcagataagg acacgcttgt tatggaactt tcttctttcc aactcatggg
     3841 tgttcaagaa ttccatccag agattgcggt tattaccaac ctcatgccaa ctcatatcga
     3901 ttatcatgga ttatttgagg aatatgtagc agccaagtgg aatatccaga acaagatgac
     3961 agcagctgat ttccttgtct tgaactttaa tcaagacttg gtaaaagact tggcttccaa
     4021 gacagaagcc actgttgtac cattttcaac acttgaaaag gttgatggag cttatctgga
     4081 agatggtcaa ctctacttcc gtggtgaagt agtcatggca gcgaatgaaa tcggtgttcc
     4141 aggtagccac aatgtggaaa atgcccttgc gactattgct gtagccaagc ttcgtgatgt
     4201 ggacaatcaa accatcaagg aaactctttc agccttcggt ggtgtcaaac accgtctcca
     4261 gtttgtggat gacatcaagg gtgttaaatt ctataacgac agtaaatcaa ctaatatctt
     4321 ggctactcaa aaagccttat caggatttga caacagcaag gtcgtcttga ttgcaggtgg
     4381 tttggaccgt ggcaatgagt ttgacgaatt ggtgccagac attactggac tcaagaagat
     4441 ggtcatcctg ggtcaatctg cagaacgtgt caaacgggca gcagacaagg ctggtgtcgc
     4501 ttatgtggag gcgacagata ttgcagatgc gacccgcaag gcctatgagc ttgcgactca
     4561 aggagatgtg gttcttctta gtcctgccaa tgccagctgg gatatgtatg ctaactttga
     4621 agtacgtggc gacctcttta tcgacacagt agcggagtta aaagaataaa atatgaaaaa
     4681 aattgtcttt acaggtgggg ggacggttgg acacgttacc ctcaatcttt tgttaatgcc
     4741 caagttcatc gaagatggtt gggaagtcca ctatatcggg gacaagcgtg gtatcgaaca
     4801 ccaagaaatc cttaagtcag gtttggatgt cactttccac tccattgcga ctgggaaatt
     4861 gcgtcgctat ttctcttggc aaaatatgct ggacgtcttc aaagttggct ggggaatcgt
     4921 ccaatcgctc tttatcatgt tgcgacttcg tccacagacc cttttttcaa aggggggctt
     4981 tgtctcagta ccgcctgtta tcgcagcgcg tgtgtcagga gtgcctgtct ttattcacga
     5041 atctgacctg tctatgggct tggccaataa aatcgcctat aaatttgcga ctaagatgta
     5101 ttcaaccttt gagcaagctt cgagtttgtc taaggttgag catgtgggag cagtgaccaa
     5161 ggtttcagat caaaaaaatc cagaaccaga tgaattggtg gatattcaaa cccactttaa
     5221 tcataaattg ccgactgtat tgtttgttgg cggttctgca ggtgctcgtg tctttaacca
     5281 attggtgaca gaccataaga aagaactaac agagcgctac aatattatca atctaactgg
     5341 agattctagc ctgaatgagt tgagccaaaa tctttttcgt gttgactatg tgaccgatct
     5401 ctatcaaccc ttgttggaat tggctgatat tgttgtgaca cgaggtggtg ccaatacgat
     5461 ttttgagctc ttggcgatag caaaattgca tgtcattgtg ccgcttggtc gtgaagctag
     5521 tcgtggtgac cagattgaaa atgcagctta ctttgtaaaa aaaggctatg cagaagacct
     5581 tcaagaaagc gatttgacct tggatagttt ggaagagaag ctttctcact tactaagtca
     5641 caaggaagat taccaagcta agatgaaagc ttctaaggaa ttgaaatctc tagcagattt
     5701 ttatcaattg ttgaaaaaag atttatcata aggaaagtaa atgtcaaaag ataagaaaaa
     5761 tgaggacaaa gaaatcctcg aagaattgaa agagttatca gaatggcaga aacgaaacca
     5821 agaatatcta aaaaagaagg ctgaagaaga agcggctcta gctgaggaga aggaaaagga
     5881 aagacaagct cggatgggag aagaatctga gaagtcagag gacaaacagg accaggagag
     5941 tgaaacagac caggaagatt cagaatcagc taaggaagag tctgaagaaa aagtagcatc
     6001 ctcagaggat gacaaagaga aagaagagaa agaagaacca gagtctaaag agaaggagga
     6061 acaggataaa aagcttgcta aaaaggctac aaaggaaaaa ccagccaaag caaagattcc
     6121 tggtatccat atcttgcgag ccttcacgat tttatttcca agtctgcttt tattgattgt
     6181 ctctgcctac ttgctcagtc cttatgcgac catgaaagat attcgtgttg agggaacggt
     6241 gcaaactaca gctgatgata ttcgacaggc ttcaggcatt caggattcgg attatacgat
     6301 taaccttctg ctagacaagg caaaatatga aaagcagatt aagtctaact attgggttga
     6361 atcagctcaa cttgtctatc aatttccaac taagttcact attaaggtca aggaatatga
     6421 tattgtggcc tactatattt ctggtgaaaa tcattatcct attctttcca gtggtcagct
     6481 tgagactagt tctgtgagcc tgaacagttt accagaaact tatttatcag ttctctttaa
     6541 tgatagtgaa caaatcaagg tttttgtctc agaacttgct caaattagcc cagaactcaa
     6601 ggcggctatc caaaaggtgg aattagcccc aagcaaggtg acatccgatt taattcgatt
     6661 gactatgaat gatttggacg aagtcttggt tccgctttct gaaatgagca agaaactgcc
     6721 ttattatagt aagattaagc cacaattgtc agaaccgagt gtgattgaca tggaagctgg
     6781 aatttacagt tacactgtgg cggataaatt aattatggaa gctgaggaaa aagccaaaca
     6841 agaggctaag gaagctgaga aaaaacaaga agaagaacag aaaaaacaag aggaagagag
     6901 caatcgaaac caaacgaccc agcgctcatc gcgtcgctag gtttaccttt tctcttatag
     6961 ttctttagtg accatgtttt tacttgacaa gtgctagtag aaataataga atagtaaaaa
     7021 acctttaaag cagtccagag aggcagctaa ggttagacgg tgaaagggtg gagactaccc
     7081 atttttcgtg gaaccttgct gttggcaggt tccttttttc gtggcttctg ttggccagac
     7141 tctctcacta gtaaaggtaa aaggagaaac ctatgcgaga acatcgtcca gtcattgctc
     7201 ttgattttcc tagttttgag gcggtcaagg aatttttagc tcttttccca gcagaagaaa
     7261 gcctttatct caaggtaggg atggagcttt attacgcagc ggggcctgag attgtgtcct
     7321 acttaaaagg tttgggtcat agtgtctttt tggatctcaa acttcatgac attcctaata
     7381 cagtcaagtc agccatgaag gtcttgtctc agcttggtgt cgatatgact aatgtccatg
     7441 cggctggtgg tgtagagatg atgaaggcgg cgcgtgaagg ccttgggagt caagctaaat
     7501 tgatcgctgt aactcagctc acatcaacgt cagaagctca gatgcaggag tttcaaaata
     7561 tccaaaccag tctgcaagag tctgtgattc actatgccaa gaagacagct gaagctggct
     7621 tggatggtgt tgtttgctcg gctcaggaag tacaagtcat caagcaggct accaatccag
     7681 attttatctg tctgacacca gggattcgtc cagctggtgc tgcagttgga gatcaaaaac
     7741 gagtcatgac acctgctgat gcctatcaaa tcggcagtga ctatatcgta gtgggacgtc
     7801 ccattaccca agctgaggat cctgttgcag cttatcatac catcaaggat gaatggacac
     7861 aggactggaa ttaaagaact agattagaaa aataaaagga gaataccatg acacttgcta
     7921 aagatatcgc tagccacctc ttgaaaatcc aagccgttta cctcaaacca gaggaaccct
     7981 tcacttgggc atctggtatc aagtcaccga tttacactga taatcgtgtg acactagcct
     8041 atccagaaac tcgtacccta attgaaaatg gttttgtgga agctatcaaa gaagcctttc
     8101 ctgaagtaga agtgattgca ggaactgcaa cagcagggat tccacacgga gccattattg
     8161 ctgataagat ggacttgcct tttgcctaca tccgtagcaa accaaaagac cacggagctg
     8221 gtaatcaaat cgaaggtcgc gtagctcaag gtcaaaaaat ggtagtggtt gaagacctta
     8281 tttcaacggg tggttcagtt cttgaagctg tagcagcagc caagcgagaa ggagcagatg
     8341 tgcttggagt tgtagcgatt ttcagctacc aattgccaaa agcagataag aactttgcag
     8401 atgctggtgt taaacttgtg acgctttcaa actatagcga gcttatccat ctagcccaag
     8461 aagaaggtta catcacgcca gagggccttg atcttctaaa acgctttaaa gaagaccaag
     8521 aaaattggca agaaggttag gtcagtaaga taaagagaga tgaggctacc gagcctcttt
     8581 tatcatttta tttaaaatat gacaatattt taaataaaat gattgacaac gctttctttt
     8641 gttgatataa tgaaaatgta atatgtatca aattgatcaa tcaactatct tgtttatcac
     8701 ttcttaggag gacgatgtca tgaaaagaag aaaaatatat tccttttttg cgtagttaca
     8761 attgcatcta gtttgtttct ccttacagtt ttagctagac agattggaga ttatgattta
     8821 acgttgccgc gttggggttc ggatacaact agtgagcttg agaaagaaaa cgcctctgct
     8881 ggaattaata ataatgacag cactggtggc ggtaaaaggt taaatacctc tattcgtagc
     8941 gcctatagtg ggtcagatat taccccggta tattcattgg ggtctggctc taggattgtc
     9001 atgtactata atggaggtgg tgacaattat attggttctg gtactagatt agctatggcg
     9061 ccacaatttg gaaatcatgt aagaattcat acttcaggtt cttggaatcc agattcttat
     9121 taacttactt gtcagagtaa gccttagaga tggttgattg tgggtgtagc atgaaaaaag
     9181 aatgctacac cctattttta ttataaggag gagtaaggat ggaatttttc atttgtaatc
     9241 ttgtacgagt cgttcaatca cctcgatttt atatgtcttt atttttgacc cttctttgca
     9301 tgagtttagg aaatttcctt gctttcaatg gtatttataa aattgaaggt ttatcgattt
     9361 tttttgccgc ttcttctatt cgaggatttt caccgattag cctagtagct gcacttatct
     9421 gtacactgcc ctattctagt cagataatag aggatgctga gagtcatttt ctaacagcac
     9481 aattgtgtcg aatttctaaa aagaagtatc tggctattgt gggtagtact gtaattattt
     9541 cttcttttct agtctttttt ctcccctatt tattattatt aggaattaat cttttagtga
     9601 ctccttatca ggaaatttat attggagatt atagtggtgc cttaaaagaa ttatttgatt
     9661 ccaatcagtt tctctatagt cttgtaacga ctctctggta tggagtttgg ggcgctgtgt
     9721 tctctatttt tggactagct agtgctttgc tagtgaagaa aaaaatagga gctattttca
     9781 tcccagttgc ctatatgatg gttggtggta ttttttgggc tattttaggg ctatcttact
     9841 tagaacctgt gacaacatta gctttgggat atcagaaaga tatcagtctt tccttagtta
     9901 gtgggcatct tgcttttatt ttatttgtta gttgtttggt tgtttatggt acattttttc
     9961 tacattcaga ggactacgta taatgaaaca atttgttcaa ttttacaaaa aagatttttt
    10021 atcagtattg gtttatttta tattactgct atcctgtgtt ttatctagta cagtatattt
    10081 attgcgctgt cgccaatatt caatccatcc aaatgtatta gaatggatct tagttttact
    10141 tcaagatatg acgactggag tatattgctt tccgttcaca tatatattgt tcttttttta
    10201 tttgatgaat aactatttta ataggttgga gtgtcgcatt cgtctgaaat caattaagca
    10261 ctttaccagt tttagtttca aattagcagc tcttagtacg gggatttgga cggcgacttt
    10321 atttttattg atttttctaa ttgcatttag taatggtttt agcttctctt tggagataaa
    10381 ggaggttgat tttttaagag aattttatgg tataagtatt gcaaacaatg ctagtttctt
    10441 tataggattt tttttctctt atatagcata ctatttcttt ttatccttac ttactattag
    10501 cagtttttct tggtttaaaa aatcaaacat gagcttagta tttctgttta cttttttatt
    10561 tgtagaatcc ttattctgga tttatcagtt ggacaatggg ataattggat tattgccaat
    10621 ttttcagtat atggtaaatt ccaatccgta tgcattgatt tattggctta cattactatc
    10681 tatcataatt ccattgactg tattttctgt tcatagaaac tggaggagag tgtaaaagtt
    10741 ggaaatggga aagttaagta gtcacatgtg gaggttgaat cagataatct ataccaagta
    10801 cttttggggt tatgttcttt tttggatatt gatttgttta ggattatggt attggttaga
    10861 aggaaatgat agacttgtta tagaaatttt aaaagggcct aatctgagtc aaaactcttt
    10921 tttagtctta tctatatggt tgcttcattg gtttattatt catacatttt ttctagcagt
    10981 tgtatatcgt agaagagcat ccgatttctt tatggaagtg attcgatttt cttctattaa
    11041 gctctggatt aggtatcaga tttggacctg ttttctttat ggactcattt taatcatggt
    11101 aaaagttcta gtgattcaat ttatgttaca gttaccaaac tgggatatag gagttttgtt
    11161 tatagttgat tctttgaatg cttgtgtgtt agtcttgttt tgctttatgt tatacgcact
    11221 aggagcgaat gtacaaatga actttgcttg cgttagtttc tttttactca tgattgtgtt
    11281 tggtggtcta tttgtaggaa atcgaactaa ttatctattt tatattttga atcgagggaa
    11341 tggagatata ggacgagatt tatttcttca gttgctattt ttagtctttc tttttaaaag
    11401 tattttctat ttcactcgtc aaaagaggag gtttatagaa tgaatgaaat aatcatatta
    11461 aaaaatattg agttgaaatt aaaaaaaaca tgtgtttttc aaaaccttaa ttttagttgt
    11521 aaacaggggg aaattatagg aattactggt gcgaatggct cagggaaaag tgtattgttt
    11581 aaattaatag ctggtttata tagtccgtct tatggagaag tgttaatcaa tggggaaaat
    11641 attgttcctg agagaaaaat tccagctaat ttgggagctt tgattgaaga acctggtttt
    11701 ataaattatt atagtggctt taagaattta caatatttgg caagcatacg aggagtagtt
    11761 ggtaatcagg aaatcaatga tacactgaaa atagttggtc tatatgagca aaaagaccag
    11821 aaagttaaaa cttattcgct aggtatgagg aaaaagctag ggattgctca agcaattatg
    11881 gagaatccct ctattctttt actagatgaa cctatgaatg ccttggataa atcaagtgta
    11941 gaaaatatga gaacattgtt tagaaagctc tctagtgaaa aagggacaac aattttgatt
    12001 gctagtcata gtgaagagga tattcgtatc ttatgtgata aagtatatgc aatagaagat
    12061 aaagtatgta cactgtgttc agattgaaca tcttagatag actcaggatg ttataggtaa
    12121 aatcttaaaa agggattgga gcttaaaatc cagtcccttt taagagttaa tggccacctt
    12181 caacaaccag gtcatctgct ttagcagcgt caccgtaggt tgggtgaagt gttttttcat
    12241 aggccttgtg gaagaagttt tccttgccta atttttcaat atctttattg atgaagtcta
    12301 gcaattcttg gttgcctttt tgaactgctg ccgcaatggt atcgggatca ccgagggaag
    12361 taattcctac ttcaaatcct ttattttcaa gcgcccaagc tagaacttcc gtattgtcag
    12421 ttgaaaaggc atctccacgt ccgtcaagaa gagcttggta agagtcactg tattggtcgt
    12481 atttttggag tttgatttct ggatgattct tttcaaaata agtctcagca gtcgttcctt
    12541 ttgtgacaat taaggtttta ccttcaagtt gtttgacgtc tgtaatgaga ccagtcttag
    12601 gtgatacgac acccagagaa actttcatat atggaagggc aaaatcaact tgtttcttac
    12661 gttcgtcagt tactgtaaag ttagcaagag taatatctac cttgtttgaa atcaagtatt
    12721 ccgcacggtt ggcagcatcg actgaaatgt atttaacctt gacaccaagg tctttagcta
    12781 gttggttccc tagttcaata tcgtagcctt ggtaagaacc atcattgtca acgtagccaa
    12841 acggtttttt atctccaaac acggcgattc gcagttcacc gccttttttt gatttcatcg
    12901 atagtgcgag ctttggcagt tgtttttcca gaggatgaac cagcgtttcc acctgagcta
    12961 caagcagtga taaagataag ggcaaaggca agtgctaaaa cagttaagag tggtttgaat
    13021 agtttcataa gaatctcctt tatagatatg agccaaattg gctaaagtca aagacgttta
    13081 aaaattcctg ggctcgtttg gtttgcggat tggtaaagaa ggcttgagct gttccttctt
    13141 cagcgatttt cccttggtcg aggaagataa tccggtcagc aatggcttgg gcaaactgca
    13201 tttcgtgggt tactaaaatc atggtacggc cttcttgggc caaatcattg ataagttcca
    13261 gcacctcacg caccatttct ggatccagcg aagcagtcac ctcgtcaaaa aggatgattt
    13321 ctggatgcat taggagggca cggacaattg caacacgttg cttctgtcca ccagataatt
    13381 gacgggcaaa gctatgttgt ttatccagca aaccgacacg atctagtaat tgcaaagctt
    13441 cttccgttac ttctttcttg tcccttcctt gagttttgat agggcctagg atgaggtttt
    13501 gtaagacatc cagatgggga aagagttcat aactttgaaa gaccatgcca atcttttggc
    13561 gaactaggtg aaaatttttt ttattttcaa cgatagactg accatccaga aaaatatctc
    13621 caccttgaat actttctaag ccgttgaggc aacgaaggag ggtacttttc ccacaaccag
    13681 atggccctag gatgacaaca acttcccctt ttttgatttc tagagaaagt ccttggagga
    13741 tgggattgtc tccgaaggat ttttttagtt ccttgatttc taagatagtt tcagacattt
    13801 agtttctcca atgtttttct aagtgagtgg atagtttgga aatagggtag caaactgcga
    13861 aatataagac tagaatggtt ccataaatcc aaaatgaagc agttgggatg gtcaggcgat
    13921 tgctatcgat gatttgttgt ccaactttgg tcacttccac aaccccaatc aaaacaacta
    13981 atgaagtggt tttaatcatc cgagtgacaa gattgatagc ctgcggtagc agtcttctca
    14041 agacttgtgg gatgatgatg tggtagtaaa gttgaacatt agtcaagccg agtgcctgtc
    14101 cactttcaaa ctgatgttta gggagagaag tgatagctcc acgtaccaag tctcccattt
    14161 cagctgttcc ccagagggta aaaacgataa tagctgaagt ctcacctgag atattgatat
    14221 taaagtttcg agccaagcca aagtaaacga tgaagagtag caccagctgg ggcatgatac
    14281 ggataaattc cagatacaat cgtgttaaaa atcgtatgat tctagaatgg gaggtcatga
    14341 tgattcccat gactgttccg aacatcatgg ataagaggac agacaggatg gatatcccaa
    14401 tcgtaacgcc caatccctgt aagattctca ggagattatt tccttgaaag agtacttgga
    14461 ttcccgaatc ctgcatggcg gagcctcctt tctatccagc taaagaccag tgagatgggt
    14521 agcagcatga tcagataagc aactaccaac atagctagcg caatgtctgt ctcatagtag
    14581 agaccaatca aatccttggc gacgtacatg aggtcggcca aagccactgc tgagaaaaca
    14641 gaggtttcct tgataaggaa aatgacattg gcactaaagg aggggagtgc caccgctgtt
    14701 gcttgcggaa gaaccacata gtaaaagacc tgtagaggtg tcagaccaat agcgaggcca
    14761 atctcctgct gggtttgact gatggcttcc agcccacttc ggaaagattc tgccatatag
    14821 gagtctccta aaaagacaag cccaagcgtt gcacagactt ctgaagatag gacaatcccg
    14881 attcggggaa gaccgaagta gagaaagaag agttgaatca aaaggggcgt attacgtgac
    14941 aattcaatgt aggctgtcgc tacttgcgac aaaacaagga ttcgataatg tcggatgata
    15001 ctaacgatta aaccgagcag aaaggatccc aaaattcccc aaactgcaat atgcaaggtc
    15061 agaaagaatg ccttttgata tagtggtaga tattgttcaa caatggatca atccaaaaat
    15121 agaacctccc atctagaaat aatacagtta ttgtagcact taaaatcttc tttggataat
    15181 atctattttt tattgccgtt ataaggattt ttatcataga cataaaattt ctgaaatttc
    15241 caaacaaaat attttaaaag ttttgaaaaa gagttaagat atttttgtaa tacacaaagt
    15301 aaacgcttac ttattaagga gg
//
LOCUS       DAVLBE010000041        15177 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.041, whole genome shotgun sequence.
ACCESSION   DAVLBE010000041 DAVLBE010000000
VERSION     DAVLBE010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15177)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15177)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15177
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.041"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(<1..678)
                     /locus_tag="VXB91_001458"
     CDS             complement(<1..678)
                     /locus_tag="VXB91_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0470890.1"
                     /translation="MKFKNYLFDLYPYFPKGFSLDNREDPDVCSKALYDDLCKMFFDD
                     DSKEKLKITSVCNKCQNYGNRDYYTLFIDKDKYLLSSDYIGASIYWAQEAGLNDRIIL
                     DHLSISRTIGGHILFPRGGKLETVNQARGGEKGYYDRFDLTLYAIKEWFVENKNTKIG
                     YAIENYHEWFELFSGDDNCKNGFENFVEFFKLEGFIYEQNKIIDLIKSDLENNQVVFL
                     DKEDILIA"
     gene            complement(694..834)
                     /locus_tag="VXB91_001459"
     CDS             complement(694..834)
                     /locus_tag="VXB91_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000899899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0470891.1"
                     /translation="MLFYLTKELNSGVKKIGTISTTLVVVAGVSAGVLGGKFDFKFPK
                     KI"
     gene            complement(788..1291)
                     /locus_tag="VXB91_001460"
                     /pseudo
     CDS             complement(788..1291)
                     /locus_tag="VXB91_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370715.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="KilA-N domain-containing protein"
     gene            complement(1508..2397)
                     /locus_tag="VXB91_001461"
                     /pseudo
     CDS             complement(1508..2397)
                     /locus_tag="VXB91_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000433508.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(2527..3624)
                     /locus_tag="VXB91_001462"
     CDS             complement(2527..3624)
                     /locus_tag="VXB91_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HEV0470892.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRAQMALENGADLVVELPFLVSVQAADFFGQGAVDILDRLGIDSLVFGTEEVRD
                     YQKIADLYTEKGTEMEKFVENLPDSLSYPQKTQAMWKEFAGLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHPIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQA
                     SKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTAQSVEELVELVTTKRY
                     TKARVRRLLSYILAQARENVLPEAIHVLGFTEKGRQHLKSLKGQVSLVSRIGKEPWDA
                     MTQKADQIYQLGNLSIAQQNFGRVPIRIETN"
     gene            complement(3634..4374)
                     /locus_tag="VXB91_001463"
     CDS             complement(3634..4374)
                     /locus_tag="VXB91_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV0470893.1"
                     /translation="MATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKERKKLLELA
                     CGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKAGKYD
                     FVTCYSDSICYMQDEVEVGDVFKDVYNALNEEGVFIFDVHSTYQTDEVFPGYSYHENA
                     EDFAMLWDTYEDEAPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYDILLEQAG
                     FKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            complement(4694..5047)
                     /gene="rsfS"
                     /locus_tag="VXB91_001464"
     CDS             complement(4694..5047)
                     /gene="rsfS"
                     /locus_tag="VXB91_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HEV0470894.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHVEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            complement(5060..5560)
                     /locus_tag="VXB91_001465"
     CDS             complement(5060..5560)
                     /locus_tag="VXB91_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEV0470895.1"
                     /translation="MKTAFIIIDVQNVLVETGFQTKSLLEKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKVAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEERFADVL
                     DYKHIF"
     gene            complement(5561..6154)
                     /gene="yqeK"
                     /locus_tag="VXB91_001466"
     CDS             complement(5561..6154)
                     /gene="yqeK"
                     /locus_tag="VXB91_001466"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HEV0470896.1"
                     /translation="MSYQDYINCSREALLEKMAELLPEKRLTHCLGVERAAMELAQRF
                     GVDVEKASLAGLLHDYAKKLSDQEFLALIDRYQLDPDLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEIHTVGAGQMTDLDKVIYVADYIEHNRAFPGVDVAREIASLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKED"
     gene            complement(6154..6783)
                     /locus_tag="VXB91_001467"
     CDS             complement(6154..6783)
                     /locus_tag="VXB91_001467"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HEV0470897.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEKNPDTDYYFIIGADMVDYLPKWYRIDELVDMVQFVGVQRPRYKV
                     GTSYPVIWVDVPLMDISSSMVRDFLAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            complement(6835..7146)
                     /gene="yhbY"
                     /locus_tag="VXB91_001468"
     CDS             complement(6835..7146)
                     /gene="yhbY"
                     /locus_tag="VXB91_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HEV0470898.1"
                     /translation="MSLTSKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            complement(7360..8466)
                     /gene="yqeH"
                     /locus_tag="VXB91_001469"
     CDS             complement(7360..8466)
                     /gene="yqeH"
                     /locus_tag="VXB91_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HEV0470899.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSDALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAHEEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMSHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFITGEKQ
                     GFTAFFDNELKLHRSKLEGASAFYDKHLGTLLTPPNSKEKEDFPRLVQHVFTIKDKTD
                     LVISGLGWIRVTGTAKVAVWAPEGVAVVTRKAII"
     gene            complement(8469..9059)
                     /locus_tag="VXB91_001470"
     CDS             complement(8469..9059)
                     /locus_tag="VXB91_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HEV0470900.1"
                     /translation="MDCFILVTKENCEKKLRKGARMAIENYIPDFAVEAVYDLTVPSL
                     QAQGIKAVLVDLDNTLIAWNNPDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVE
                     KFGIDYVYWALKPFTFGIDRAMKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKP
                     LVQHDSIKTQINRTRERRVMRKITEKYGPITYKKGI"
     gene            complement(9011..9919)
                     /locus_tag="VXB91_001471"
     CDS             complement(9011..9919)
                     /locus_tag="VXB91_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEV0470901.1"
                     /translation="MVLEKQLGNGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESGTVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLENHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNLFA
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDKPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            complement(9976..10536)
                     /locus_tag="VXB91_001472"
     CDS             complement(9976..10536)
                     /locus_tag="VXB91_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HEV0470902.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQALHFVPNRNITVVSNFSRTD"
     gene            10675..11884
                     /gene="sstT"
                     /locus_tag="VXB91_001473"
                     /pseudo
     CDS             10675..11884
                     /gene="sstT"
                     /locus_tag="VXB91_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713440.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            11952..12905
                     /locus_tag="VXB91_001474"
     CDS             11952..12905
                     /locus_tag="VXB91_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEV0470903.1"
                     /translation="MSISQRTTKLILATCLACLLAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREEEIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIERYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYRQ"
     gene            13048..13428
                     /locus_tag="VXB91_001475"
     CDS             13048..13428
                     /locus_tag="VXB91_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV0470904.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETVAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTND
                     GQKILASLQKTVEESLEAGLDFLI"
     gene            13527..13748
                     /locus_tag="VXB91_001476"
     CDS             13527..13748
                     /locus_tag="VXB91_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEV0470905.1"
                     /translation="MIEITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            13765..14079
                     /gene="trxA"
                     /locus_tag="VXB91_001477"
     CDS             13765..14079
                     /gene="trxA"
                     /locus_tag="VXB91_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEV0470906.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
     gene            14384..14917
                     /gene="queF"
                     /locus_tag="VXB91_001478"
     CDS             14384..14917
                     /gene="queF"
                     /locus_tag="VXB91_001478"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 7-cyano-7-deazaguanine reductase
                     QueF"
                     /protein_id="HEV0470907.1"
                     /translation="MKRQSALVVFSGGQDSTTCLFWVMQHYETVEAVTFAYGQRHHLE
                     IQIAREIAKEQGIRHHILDMSLLGQITAQPDFATIHISYIPDKLCVESKSLKLYLFSY
                     RNHGDFHENCINTIGKDLVNLLDPRYLEVWGKFTPRGGISIDPYYNYGKQGTKYEDLA
                     EQRLFQHDLYPEKIDNR"
     gene            14967..>15177
                     /locus_tag="VXB91_001479"
     CDS             14967..>15177
                     /locus_tag="VXB91_001479"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0470908.1"
                     /translation="MLKAVFEVVDKTDEVSSKHCFEVADRTDKVSLKHCFEVADRTDE
                     VSLKHCFEVADRTDEVSLKHCFEVVD"
BASE COUNT         4331 a         3339 c         2888 g         4619 t
ORIGIN      
        1 agcaatcaaa atatcttctt tatctaaaaa gacaacctga ttgttctcta aatctgattt
       61 aattaaatct ataattttat tttgctcata tataaatcct tctaacttga aaaactcgac
      121 aaagttctca aatccatttt tacaattatc atcaccagaa aatagttcaa accattcatg
      181 gtaattctct atagcataac ctatttttgt atttttattt tccacaaacc attcttttat
      241 agcatatagt gttaaatcaa aacgatcata atatcctttt tctccacctc tagcctgatt
      301 aacggtttct aattttccac ctctagggaa aagaatgtgt ccacctattg ttcttgaaat
      361 actcaaatga tctaaaatta ttctgtcgtt taatcctgcc tcttgtgccc aataaataga
      421 ggctcctata taatcacttg ataataaata cttatcctta tcaataaata aagtataata
      481 atctctattt ccatagtttt ggcatttatt acatacagat gttattttaa gtttttcttt
      541 tgaatcatca tcaaaaaaca tcttacataa atcatcgtac aacgccttac tacatacatc
      601 aggatcctct ctattatcta atgaaaaacc tttgggaaaa taaggatata aatcaaatag
      661 ataattttta aacttcatat ttattattct ccattaaatc tttttaggaa atttaaagtc
      721 aaattttcct ccaagcacac ccgcacttac tcccgcaact actacaagtg ttgtactaat
      781 tgttcctatt ttcttcacgc cactgtttag ctcttttgtt aaataaaaca acattgatca
      841 tatctgcttc acttacatac ttgtaagaca actgttcgtt ggtaagatct tttaagagat
      901 attctttgat tgcatctgta tgaattttgt agttaatctt agaaatttct ctattcaaat
      961 tccagcctaa tgatagctta gaattttaat ctgacttaag tcttttgtaa tcctgaatta
     1021 catacatctt aaattcagca gaaatacata aagcaaattc aaaggcaata tctgtatgtg
     1081 caaatgcacc accatatctt ccaccttttg agataattcc gattgctcca gttttctcta
     1141 cccatttctt aggagacaat gtaaatgaat tatatccagc ttccgattta attcggtcga
     1201 attcgaccga attgaaattc atgttattta agcttttcca taaaccaaga aactcaattg
     1261 tatcttttct tctcatccaa tttttaatta catcactcga tacttatccg aacgataagc
     1321 tccacgtaag gtgttcgcaa tcgaccaaac tgcattgact acatttgaaa tctgaacatc
     1381 gttcgactgg aatatcggta gtttttcttt aaaattagac atttgcttcc cctgttttta
     1441 tgatttacaa ttctcttcat tataccacaa aataggcgct ttgtcaactg tagtgggttg
     1501 aagtcagcta agctcgagaa aggacaaatt tcgtcctttc ttttttgatg ttcaaagcga
     1561 taaaaatccg ttttttgaag ttttcaaagt ttcgaaaacc aaaggcattg cgcttgataa
     1621 gtttgatgag attattggtc gcttccagtt tggcattaga atagtgtagt tgaagggcgt
     1681 tgataatctt ttctttatct ttgaggaagg ttttaaagac agtctgaaaa ataggatgaa
     1741 cctgcttaag attgtcctcg ataagtccga aaaatttctc tggttcctta ttctggaagt
     1801 gaaaaagcaa gagctgatag agctgatagt gatgtttcaa gtcttgtgaa tagctcaaaa
     1861 gtttgtctaa aatctcttta ttggttaaat gcatacgaaa agtaggacga taaaatcgct
     1921 tatcactcag tttacggcta tcctgttgta tgagcttcca gtagcgcttg atagccttgt
     1981 attcatggaa ctttcgatcc aattgattca tgatttgaac acgcacacga ctcatagcac
     2041 ggctaagatg ttgcacaatg tgaaagcgat caagaacgat tttagcattc gggagtgaaa
     2101 cagtctggga gactgtttca gcctgagcct agaaatttga aagcgaagct gtttagccaa
     2161 gtcatagtaa gggctaaaca tatccatagt aataattttg acgcgacatc ggacagctct
     2221 atcgtagcga agaaagtgat ttcgaatgat agcttgtttt cttccctcaa gaacagtgat
     2281 gatattgaga ttgttaaaat cttgcgcaat gaagctcatc tttccctttg taaaagcata
     2341 ctcatcccaa gacataatct caggaagacg cgaaaaatca tgtttaaagt gaaaatcaaa
     2401 gagcaaacta ggaaactagc cgcaggctgt acttgagtac ggcaaggcga cgttgacgcg
     2461 atttgaattt gattttcgaa gagtattatt cgtaaaaaat ctcaaaaagt ccacctttcg
     2521 gtagacttag tttgtttcta ttctaatcgg cactcttcca aaattctgtt gtgctatact
     2581 tagatttcct agttggtaaa tctggtctgc tttttgggtc atagcatccc aaggttcttt
     2641 gccaattcgg ctgactagac tgacctgacc tttcaaagac ttgagatgtt gcctgccttt
     2701 ttcagtaaat ccaaggacat gaatggcttc tggcaagaca ttttctctag cctgcgccaa
     2761 gatataggac aagaggcgtc tgacacgcgc cttggtgtaa cgtttggtag tcactaactc
     2821 gaccaattct tccacagact gggctgtttt aatagcttct ttaatgcgca cagccatttc
     2881 ttgattgacc tgatagatgg tggttaggtc gggatttgac aagatttgat agcggagcaa
     2941 gggaaaatag tcttcccaga tcaccttact ggcctgctca aatagggcaa cagaaggcat
     3001 aaaacgttct aagaaatctt ggtccttctg atgttgacgg agggctgtcg ccgaggcaaa
     3061 gtccacatct ttattcacag aatggtaacc tgccccctga cgctgaatcg gatgcagctt
     3121 gatattccgt cctgcaaccg ccttggcata ggccagagca agaacatgat tgggggtatt
     3181 acctgaaaaa tcaagaccag caaattcctt ccacatagct tgggttttct ggggatagga
     3241 aagggaatca ggcagatttt ccacaaattt ctccatctca gtacctttct ctgtgtataa
     3301 gtcagcgatt ttctgataat ctcgaacttc ctctgtccca aaaactagac tatcaatgcc
     3361 caagcgatcc aagatatcca cagctccttg accaaagaaa tcagctgcct gaacactgac
     3421 taaaaagggc aattccacta ccaagtctgc gccattttcc agcgccatct gggcccttgt
     3481 ccacttatcc acaatagcag gctctccacg ctgcatgaaa ttccctgaca tggcaacaat
     3541 tttcagtccc tctgcctgat ccagcaggta tttatggcca ttatgaaaag gattgaactc
     3601 tgcgataata cctgtgatgg tcatgatgtt ctcctacttc tgcgccacaa aaaaccaacg
     3661 ggtgctagtt tctgttggct ccttatcctc aaagtctgca tagagtttga aggacttaaa
     3721 tccagcctgt tccagcaaga tatcataggt caagatctca taggtcctct cctcatgtac
     3781 ttcatcgtgg cgactaaagg aaccgtcagc ctccttgata aagaaagtca gctcatgcac
     3841 gatggagtga ggagcttcgt cctcatatgt atcccaaagc atggcaaaat cttccgcatt
     3901 ttcatggtag gaatagccag ggaatacttc atctgtctgg taggtcgagt gcacgtcaaa
     3961 gatgaaaact ccctcttcat tcagcgcatt gtacacgtcc ttaaagacgt cccctacttc
     4021 cacctcatcc tgcatatagc agatagagtc cgaataacac gtgacaaaat cgtatttccc
     4081 tgccttggac aaattcagca tattaccttc tataaaagca atcttttgct tggctgaagt
     4141 tgctctcttc tccgcaatct tcaacatatc cgcactcaag tcaagtccag tcacatcaaa
     4201 accagcctga gagaagcgca ctgattgaat tcctgtccca caagccaatt ccaagagttt
     4261 ctttctctcc ttggtcttag gcaaatgacg cagagaaaaa ttcgtccatt tgtcgtataa
     4321 actatcgtcc atgaccgcat catagaccgc cgcaaaggtt tcataagtcg ccataaaaca
     4381 tgataccaag tccgcccgta attcgataga aaattaggag ccttacgatg gagccgagct
     4441 ccaaggaagg ctatctattt tccgagaatt acaggacggg ttcaaatcct ttctaagata
     4501 caaagagcct taaaagcaaa gagtacatag gaaactttct tccctatcgt cagatacaaa
     4561 gaaagttact ttttatctca gcttttagct cgtgttcagt ttcgaaatga aacaaacacg
     4621 aggcccttta cctttctatc aatttttcta aaataagcaa agaaacccag ttgactacaa
     4681 ctgagttcat cttctaagca agagcttctg aaatatctac tgaattcgcc tcatgccata
     4741 gcttctctag attataatgg gcacgcattt cttctgaaaa gatatgcacg acaacagcac
     4801 cgaggtccag taagacccag cctccagctg catcgccttc gacatggcta cctttaaagc
     4861 ctgcttgagc tactttttca cggatattag ctgcgatagc gtccaactga cggctattca
     4921 ttgagctagt gatgacaaag tagtccgtca cactagtcaa atcttgtaca tcaagtgcga
     4981 ggatatcctc cgcacgtttc tcatcagccg ctttcacgac tagttctagt aattcttttt
     5041 cgttcattta atcctctttt tagaaaatat gtttgtaatc tagaacatct gcaaagcgct
     5101 cctcccaaat gtcctcataa aattcattaa tcgtttctgc tggaatgtca tccccatcaa
     5161 aggttgtgac agcaccttct ggaacaataa gctgatagcc atattcaaag gcaaccttga
     5221 cagaggtatc cacacaatat tctgtctgca taccacataa aactaatttt tcaatcccct
     5281 gcttatccaa gtattctttt aagccagttt ctttgaaaat actgttatac ttcttctgaa
     5341 agaccttttc agcaggtttt cgatttaaaa gcgcagataa ctgccaatct tctgatgttt
     5401 gagcttcaga gttctcaata tgttgaacat agataatttc aatattcttg cttctagcct
     5461 ggttttgtaa ataagaaatt ttttccaata gactttttgt ctggaaccca gtttctacta
     5521 aaacattctg aacatcaatg attataaaag ccgtcttcat ttagtcctct ttcaaatagt
     5581 gcacaaaggc gttataggtt tcaagggttt ggggatagat ggggaatccc tgatgagcta
     5641 gatactccac ggtacgagct gtttcgtagg ccaccgcctt attgagcgat agacttgcaa
     5701 tctcacgcgc cacatccact ccaggaaatg cccgattgtg ctcgatatag tctgcgacgt
     5761 agatgacctt atctaggtct gtcatttgac cagctccgac tgtatgaatt tcaatggctc
     5821 gcagaatttc agaatcatgc aaatccaaat cttcctgaat tttgtaaatt ccgaccatac
     5881 catgccagac attgttgccc cagtttttga ggtcagggtc tagctggtaa cggtcaatca
     5941 aggctagaaa ttcctgatct gacaactttt tagcatagtc atgaagaaga cctgctagac
     6001 ttgctttctc aacatctaca ccaaagcgct gagctaattc catagcggca cgctccacac
     6061 ctagacaatg ggttagacgt ttctcaggta gaagctctgc cattttttcc aacaaggcct
     6121 cacgggagca gttgatatag tcttgatagg acatcagtag agcccctcct tctcgatgta
     6181 gtctagcact ggctgaggta ggagaaagtt gggtttccga ccttgggcaa ggaagtcccg
     6241 caccatgctg gacgagatat ccatgagcgg tacgtccacc cagataactg gataggaagt
     6301 ccctaccttg tagcgtggac gctgaacccc cacaaactga accatgtcaa ccagttcatc
     6361 aattcggtac cacttaggca gatagtcaac catgtcggca ccgatgataa agtaataatc
     6421 cgtatctgga ttcttctctg tcaaaatctt catggtgtcg taggtgtagg aaataccctt
     6481 gcgctccaac tcaatggttt caatgactag gccgtcaatt ccctcaattg ccaactcaag
     6541 catcttgaga cgatggtgtt cagggatggt ttccttttta tcaacgtgag gaggttggta
     6601 ttcaggcatg agcagaactt gatccagtcc caactgttgc cgtacttgat ccgcaacaat
     6661 aagatgggca ttgtgaacag ggttaaaatt cccccctaaa atcccaactt gtttgcgttt
     6721 tttctccttg atttctggct ccaactctac cttggtaaag ggagtcaata gttcgattgt
     6781 cataggctag tcccctttat ttctctatga aaacagttat ttggagtttc ggtcttagat
     6841 ttctttgact ttcttagaaa tcttgcgatt ttctttcttg ctagattgtt taaacaaaat
     6901 caagatgcgt cctatttttt ggactgtatc cacaccgatt tcttcttcca aaatttcagc
     6961 tacttcgtgg atgttttcat ctgtgttttg taagagagta accttgatta attcacgcgc
     7021 atcaagagct tgacggacgc tggttttgat ttggtcgttg agtccatttt tcccgatttg
     7081 gatgataggt ttgagggtgt gtgcctggct gttgaggaag gcacgttgtt ttgatgttaa
     7141 tgacataatt ttcttccttg ttttttgata gttattttag gtggtgaggg acggtcggaa
     7201 ctaattttcc aaagatttca tctttgaaaa atggatttcc tgacctcaca attgagcctt
     7261 ggtctcaatt gtgccccttg ccaatctaca gattggcaat cacaccacgg caataactat
     7321 cgctatatga gctcactttg ttcgctcagc gattttgttt taaataattg cttttcgtgt
     7381 gacgacggcg acgccttctg gtgcccagac ggcgactttt gctgtgcctg ttacacgaat
     7441 ccagcctagg cctgagatga ctaggtctgt cttatcttta atggtaaaga catgctggac
     7501 tagccttggg aaatcttctt tttccttgct atttggtggt gtcagaagag ttcccaggtg
     7561 cttatcgtag aaagcactag ctccttcaag cttgctacga tggagtttga gttcattgtc
     7621 aaagaaagca gtaaatcctt gcttttctcc tgttataaag tcaaagcgtc ccaaaccacc
     7681 taaaaatagg gtttgctcag gattaagctg ataggtctta ggcttgattt cctttttagg
     7741 actgacatac ttgaggtttt tggccgtcaa atagtgagac atctggtggc ggtggataat
     7801 tcccggcgta tcgtaaatat aagatccgtc gtcaagcgga atctctattt tgtccaaggt
     7861 tgtccctggg aagcgtgaag tagtgatgac attctgatca cccgtgattt cttggataat
     7921 agcattgatt agagttgatt ttccaacgtt ggtcacaccg accacataga catcgcggcc
     7981 cttacggtag tgttcaatct tgtcaatgac ttccttaatg gcatgtttat tttgtgctga
     8041 agttaggacc acatcgactg gacgaagacc ttcttcatgg gcacgtttca tgagccactg
     8101 gctaatctta ccagacttaa ctgacttagg aaggatatct tttttatttc ctaccaagag
     8161 gacatcattg cccgagacga aacgtggtaa acctgggatg acagatccat taaaatcaaa
     8221 gatatcaatg acattgacca ctaaagcatc actgtctccc acctcgtgca agagcttgag
     8281 gaaatcatcg ttcgtcaact ggacatctgt gatttcattg tagtggcgga gacggaaaca
     8341 gcgttggcaa tagacttcgc cagtctccaa acctttttca agtgccgact ggggggtaaa
     8401 accaagacca gctttatctg tcgtctgaat ggttgctcca caaccaatac agagaatttc
     8461 ttccatagtt aaattccttt tttatatgta atcggtccgt acttttcagt gatttttctc
     8521 ataacacgac gctcacgagt tcggttaatc tgcgttttga ttgagtcatg ttggaccaag
     8581 ggtttgacta aaattgaccg aatccctgca cggtgggctg ctcgtatatc tgtcatgagc
     8641 tggtcaccaa ccatgaccac ttcctttttg tcatagtgga attccttcat ggcacggtca
     8701 ataccaaatg tgaagggctt caaggcccag taaacgtaat caatcccaaa tttctcaact
     8761 gctcgttgaa cgcgtttttt ggtgttattt gacactacga taatgccaat acccgcgtcc
     8821 cgaaggtcat gtagccattg cttcatctct ggcgttccat cagggttgtt ccaagcaatg
     8881 agggtattat ccaaatcgac caaaacagcc ttgattccct gcgcctgcag gcttgggact
     8941 gtcagatcat agactgcttc cacagcaaaa tctggtatat aattttcaat cgccattctg
     9001 gctccttttc ttaacttttt ttcgcaattt tccttagtaa caaggataaa acaatccaca
     9061 aacctgcact agccaaactg atatagagcc aagcatgggg cttatctgtt aaaggtaagg
     9121 gaacattcat tccgaaaaag cctgtcacga ctgccaaaac agctagcaag actgaaatga
     9181 tagtcaaggt tgtcaaattg tcattcagat tattgtttag aatattgttg taagaggctg
     9241 aaagctgctg taaaatctga gagattaggt ctgtcatgga taccagctga tgagcctcaa
     9301 tcatggcatc atcaaactgt tctctctcaa tctcatcaaa actacgatac aaggcatgac
     9361 cttgaatatg ctctaacaaa atccgatttt gtttggcagc tgccgtcaga taaaccatac
     9421 cagtctccaa atcagacagg gcaaagaggt ttttcttggt agttcgctgg cgcaagaggt
     9481 cattgacctc atccctactc ttgtccatct gctcaatgac aggatagtag gcattgctga
     9541 tgatttccag actggcaaag agaaacttat aaatcgaaag cgtgtcatgg ttctccagat
     9601 aacgagtcat ctgttcaatg acataggcgt tcttggtatt actaatggta atcaggcgac
     9661 gatgctcgac aataaaggtc atgggaaaag tctcatagta ggccttgtcc ttttttacgt
     9721 ctaggacatt atagataaag gtaaccgtcc cactttcacg gtggtagtcc atgtgggcgc
     9781 gctcgtttct atccagtgcg tattcaatgg tttccttgtc caaaccgtaa atttcagaaa
     9841 ggtcttctag tttattcaac tttcctaggt ctaggtctat ccaggtacaa ccattgccca
     9901 actgcttttc taaaaccatc ttttctcctt attaaactcc ctctattgta ccacaaatta
     9961 cttaaaataa caggtctagt ctgtgcgtga gaaattgcta acaactgtga tatttcggtt
    10021 agggacaaag tgaagggctt gctcctcgct acgaagctgt gtcgtacgaa ttcccacact
    10081 gacaacctta cccgatacag taatcggtcc atttgtcaga acgacctcat ctcccacatc
    10141 cagttgacgt tcaaagagga tgaaaaagcc attgatgaca tcagacagaa agccttgggc
    10201 tcccatacca atcgctaccc cagcaatacc agctccagcc agcaaactag aaactggcaa
    10261 acctaaaatc gacaaaatgc agtagagtaa aaagaaatat agcgtataat taaacacatt
    10321 ttctagtaaa cgtgagatgg ttttttggcg tccgacatca tgacgagaca tttttagaga
    10381 aggtttgaca attctctgca ccatggtatg aagcattttt ttagcaatat aaaatacaat
    10441 caaaagcagt aaaagagaaa tgaccttggt tagaatattc tcgataatgg ttgtcacatc
    10501 tagcttttca atataagcct gaataaattt ttgcatataa aactccttta tttcattata
    10561 ccatattttc atcagtctca ttctccataa atattcaaaa aatagacaga aaattcttga
    10621 ttttgtctat catttatact ataatcataa tcactacaca aaaaggagat tattatgaaa
    10681 agaatcattc atgcttggaa taaggcaagc cttgtcaagc gtatcttgat tggtatgctt
    10741 tgtggggaat cctaggactg acccttccta atctctcagg gattgggcta ctcggggatt
    10801 tattcgttgg aggtctgaaa gctgttgctc ctatcctagt ctttgccctc gttgccaatg
    10861 ccctttccca acatcaaaag ggacaagata gcaatatgaa aactgttgtt ttcttgtata
    10921 tcctatgata gggactttcg ccgctgctct tgtagctgta ctagcaagtt tcatcgtccc
    10981 tattgaaatt accctaaata gtgccaatac tgaaattgca ccaccagatg ggattgggca
    11041 ggtcctcagc aacctcttgc tcaaactggt tgacagccca gtcaacgccc tgcttactgc
    11101 taactatatt ggaatcttat cttgggcagt catttttgga atcgctatga gagaagctag
    11161 taaaaatagt aaagaattgc taaaaactat cgctgacgtg acttctaaaa ttgtcgaatg
    11221 gatcatcaat ctggctccat ttggaatcct tggtcttgtt tttaaagcca tttctgacaa
    11281 gggagtcgga agccttgcca actacggtat tttattggtt ccattagtaa cgactatgct
    11341 ttttgttgcc cctgtggtca accctttgat tgccttcttc tttatgagac gcaatcctta
    11401 ctctctagtt tggaactgcc tccgtgtcag cggtgtgaca gcctttttca ctcgtagttc
    11461 tgcgactaac attcctgtca acatgaaact ctgccatgac cttggactca acccagatac
    11521 ctattctgtt tctatcccac tcggttctac tatcaatatg gctggagtag cgattaccat
    11581 taaccttttg acccttgctg cagttaacac tcttggaatt cctgttgact ttgccacagc
    11641 ctttgtcctc agtgtggtag cagctatctc atcctgtgat gcttcaggta ttgccggagg
    11701 ttccctcctt cttatcccag ttgcttgtag ccttttcggt atttctaacg atattgccat
    11761 acaaattgtt ggggttggtt ttgtgattgg tgtcatccaa gactcatgtg aaacagccct
    11821 taactcttct acagatgtcc tctttaccgc cgttgccgaa tacgcagcaa cccgtaaaaa
    11881 ataactcatc aaggcaagcc tgctcatgtc ttgtctttta cgcttttatt ctaacttatt
    11941 aggaaattct tatgtctatt agccaacgta cgaccaagct catcttagct acctgtcttg
    12001 cctgcctgct tgcttatttt ctcaatcttt cgtcagcagt ttcggctgga attatcgctc
    12061 tcttgagcct atctgatacg cgtagaagta ctttaaaact ggctcgcaat cgtctttttt
    12121 ctatgcttct agctctggct atcggtgttc tagcttttca cttgagcgga tttcatatct
    12181 ggagtctcgg cctctatctg gccttctacg ttcctttagc ctacaagatg ggctgggaaa
    12241 ttggcatcac accaagcact gttttggtta gccatctctt ggttcaagag tcaacctctc
    12301 cagaccttct agtcaatgaa ttccttctct ttgctattgg tacaggattt gccttgcttg
    12361 ttaatctcta tatgccttca cgagaagagg aaatccagca ctaccacacg ctggtggaag
    12421 aaaagttaaa agatatcctc cagcgcttca aatactattt atccagagga gacggacgca
    12481 accgagcaca gctggtagca gaattagaca cgcttttgaa agaagccctc agactggtct
    12541 atttggatca ctctgaccac ctctttcacc agaccgacta ccatatccac tactttgaga
    12601 tgagacagcg acaaagtcgt atcctgagaa acatggccca acagattaac acttgtcacc
    12661 ttgccgccag tgaaagcctg atcttagcgc aactcttttc aaaaattgca ggtcaactga
    12721 gccagaccaa tcctgcttct gatttgctag atgaaattga acgttatctg gaagtcttcc
    12781 ggaaccgcag tctgcccaag acaagagaag aatttgaaac ccgcgccacc cttcttcaac
    12841 tcctacgtga agccaaaacc ttcatccaag taaaagttga tttttaccaa aaatatagac
    12901 agtaaaaaat aaaaccacta aaaaacagag cttgccagca ttcttgaaaa gtagtataat
    12961 tattgcatgc gcaatcatct tgtgacgcag agactgcccg ttaatggact ttcttctatt
    13021 tatgactcta aaaagaaagg agacactatg acctatttgg aaaaatggtt tgacttcaat
    13081 cggcgtcaga aagaaattga aagtctcttg gaagagaccg ttgcccaaca gagcgagcaa
    13141 agtctgacct tgaaagagtt ctacctgctc tactatctgg acttggctga agaaaaatct
    13201 ctacgccaga ttgacctgcc agataagctt catctgagcc cgagcgcagt ttctaggatg
    13261 gtggctcgct tggaagctaa aaattgcggt ctactcagtc gcatgtgttg ccatcaagat
    13321 agacgctcta gttttatctg cctgacaaat gatgggcaaa agatactggc ctcgctacaa
    13381 aagactgtcg aagaaagctt ggaagcaggt ttggatttct tgatttaaga tgattttaga
    13441 aaaagttgcg tgcgcaatca tttttcttga cattctcttt tataaggagt aaaataaagt
    13501 tagcattaaa caaaggagtt ttaaatatga ttgaaattac ctatatagat gccagcaaga
    13561 acgaaagaac tgtgactttc gagtcttatg aagactttga acgttcgcaa caagcttgcc
    13621 ttatcggcgt cgcagactac taccctgtcc aaaaattaac ttacaagggt cataatttgg
    13681 actaccatgg gacttatgga gatatcttct tctatctcat gaaacaagat ttaagccaat
    13741 ataactaaaa aaaggagaaa tacaatggca aaagcaatta cagatgcaac attcgaacaa
    13801 gaaacaaaag acggtttggt cttagtagac ttctgggcaa cttggtgtgg tccatgtcgt
    13861 atgcaaggtc caatcttgga caaattgtct gaagaacttt cagaagatgt cttgaaaatc
    13921 gttaaaatgg acgttgatga aaatccaaac acagctcgtg cttttggaat catgtctatt
    13981 ccaactcttc tcttcaaaaa agacggccaa gttgtcaaac aagttgcagg tgttcacaca
    14041 gcagaacaaa tcaaggccat cattgctgaa ttgagctaat caaacgagag accaagtact
    14101 ttctttggtc tcttttttct tgccctttgc catttttcaa aaaatatgct agactatagt
    14161 agattgaaac tagaatagta cacctctact tctaaaacat tgttagaaat cgatttaact
    14221 gtcctgatcg atttgtcctg ttcttatttc attttactat ataagtagaa tattacgatg
    14281 tttgggatat gccatcgcta aaaaaactcg atttggtatt ttttagctcc ctaataggag
    14341 ctttttgcat gctctgaaca tttcccattt tggaaggagt actatgaaac gtcaatcagc
    14401 cttggtcgtc tttagtggtg gtcaagattc aacaacctgc cttttctggg ttatgcaaca
    14461 ctatgaaaca gtcgaagctg tcacctttgc ctacggccaa cgtcatcacc tcgaaattca
    14521 aattgctaga gaaatcgcta aggaacaggg cattcgtcac catatcctcg atatgtctct
    14581 gctgggacaa atcactgctc agccagactt tgcgacgatt catatttcct acattcctga
    14641 caagctctgt gtcgagtcaa aatccctcaa actatatcta tttagctacc gaaatcacgg
    14701 agatttccac gaaaactgta tcaacaccat cgggaaagac ttggtcaact tgctagaccc
    14761 tcgctattta gaagtctggg gaaaattcac tccgcgcggt ggcatttcaa tcgaccccta
    14821 ctacaactac ggtaagcaag gaactaagta tgaggacttg gcagaacaac gcctcttcca
    14881 acacgacctt tatccagaga aaattgacaa ccgctaaagt catactcaat gaaaatcaaa
    14941 gagcaaacta ggaagttagc cgcaggttgc tcaaagcagt gtttgaggtt gtagataaaa
    15001 ctgacgaagt cagctcaaaa cactgttttg aggttgcaga tagaactgac aaagtcagct
    15061 taaaacactg ttttgaggtt gcagatagaa ctgacgaagt cagcttaaaa cactgttttg
    15121 aggttgcaga tagaactgac gaagtcagct taaaacactg ttttgaagtt gtagatg
//
LOCUS       DAVLBE010000042        14738 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.042, whole genome shotgun sequence.
ACCESSION   DAVLBE010000042 DAVLBE010000000
VERSION     DAVLBE010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14738)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14738)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14738
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.042"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(112..861)
                     /locus_tag="VXB91_001480"
     CDS             complement(112..861)
                     /locus_tag="VXB91_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HEV0470909.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTDKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMTLKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            994..3330
                     /locus_tag="VXB91_001481"
     CDS             994..3330
                     /locus_tag="VXB91_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HEV0470910.1"
                     /translation="MDKNKIMGLTQREVKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNFAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLSQVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLMETYGEEAIASILTSYMA
                     HSEDKNPTAQAIRQRFVGDVAYPMISNLPFSSDRKWGAMELEGLGTVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDSIREGAAETLDY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHNYVDCSKITDEELMAMAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEQNFLRKSMLRALPSALMVVFSVLFVKIF
                     GSSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEISTLTGQTLPVYGVMMLVFTVIFILTSRYQARK"
     gene            3432..4109
                     /locus_tag="VXB91_001482"
     CDS             3432..4109
                     /locus_tag="VXB91_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HEV0470911.1"
                     /translation="MISKRLELVASFVSQGAILLDVGSDHAYLPIELVERGQIKSAIA
                     GEVVEGPYQSAVKNVEAHGLKEKIQVRLANGLAAFEETDQVSVITIAGMGGRLIARIL
                     EEGLGKLANVERLILQPNNREDDLRIWLQDHGFQIVAESILEEAGKFYEILVVEAGQM
                     KLSASDVRFGPFLSKEVSPVFVQKWQKEAEKLEFALGQIPEKNLEERQVLVDKIQAIK
                     EVLHVSK"
     gene            4096..4893
                     /locus_tag="VXB91_001483"
     CDS             4096..4893
                     /locus_tag="VXB91_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HEV0470912.1"
                     /translation="MLASEVIQAYEAFCPQEFSMEGDSRGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLGIEETTYLQETGPERGIGRIGNIQPQTFWELAQQVKQVFDLDS
                     LRMVHYQENDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIAALLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            4910..6013
                     /locus_tag="VXB91_001484"
     CDS             4910..6013
                     /locus_tag="VXB91_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HEV0470913.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWFSKRRNKAWYKMARLGADFYVDLLADLEKSGQEIDFYQRSGVFLLKKDESKLE
                     ELYQLALQRREESPLIGQLAILDQASANELFPGLQGFDNLLYASGGARVDGQLLVTRL
                     LEASHVKLVKEKVTLTLLSSGYQIGEEVFDQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLAQDMEDYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDEPLLQQME
                     EAALPHYPVLARVTSRAERVGIRAYTSDFSPFFGQVPELAGVYAASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPLNYPIENYVKRVKSE"
     gene            6314..7333
                     /gene="galE"
                     /locus_tag="VXB91_001485"
     CDS             6314..7333
                     /gene="galE"
                     /locus_tag="VXB91_001485"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEV0470914.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTATLRDIFKQEEPTGVIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKAMEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            7335..8288
                     /locus_tag="VXB91_001486"
     CDS             7335..8288
                     /locus_tag="VXB91_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV0470915.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAVHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTYYLDYPNVERQAGKTSWSFRQLFFYSIE
                     GIVNFSDFPLTIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSDLPDFTEKIK"
     gene            complement(8350..8556)
                     /locus_tag="VXB91_001487"
     CDS             complement(8350..8556)
                     /locus_tag="VXB91_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HEV0470916.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSQDVLEAVKNCPTRALIGNQEA"
     gene            8608..9084
                     /locus_tag="VXB91_001488"
     CDS             8608..9084
                     /locus_tag="VXB91_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM domain-containing protein"
                     /protein_id="HEV0470917.1"
                     /translation="MAKEPWQEDIYDQEESRAGRRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKDFHDSDASVVQISSSSSSQPEQSSEPESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK"
     gene            9093..9764
                     /locus_tag="VXB91_001489"
     CDS             9093..9764
                     /locus_tag="VXB91_001489"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HEV0470918.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLGVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDLETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            9895..10233
                     /locus_tag="VXB91_001490"
     CDS             9895..10233
                     /locus_tag="VXB91_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HEV0470919.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLTDGDTVTLIKDLKVKGAPKDLKQGTRVKNIRIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            10236..10865
                     /locus_tag="VXB91_001491"
     CDS             10236..10865
                     /locus_tag="VXB91_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HEV0470920.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITRHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            11105..12256
                     /locus_tag="VXB91_001492"
     CDS             11105..12256
                     /locus_tag="VXB91_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV0470921.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGTRLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVMPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            12569..13318
                     /gene="truA"
                     /locus_tag="VXB91_001493"
     CDS             12569..13318
                     /gene="truA"
                     /locus_tag="VXB91_001493"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HEV0470922.1"
                     /translation="MTRYKATISYDGYAFAGFQRQSHARSVQEEIEKTLTRLNKGQTI
                     TVHGAGRTDSGVHALGQVIHFDLPYQMDEEKLRFALDTQSPEDIDVISIELVADDFHC
                     RYAKHSKTYEFIVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IDLILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            13308..14081
                     /locus_tag="VXB91_001494"
     CDS             13308..14081
                     /locus_tag="VXB91_001494"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEV0470923.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNGLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     LIKGDKLLPAVESSKAFVYRAIAQADQYGVRQYEANKNN"
     gene            14059..14520
                     /locus_tag="VXB91_001495"
     CDS             14059..14520
                     /locus_tag="VXB91_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV0470924.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLIDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     ATIAMVGGYALGSTLMNGWAAALPEILPNFMQNMVGMIVGFILSQSIKKIK"
BASE COUNT         4080 a         2835 c         3453 g         4370 t
ORIGIN      
        1 aggacagtca aatcgatttc taaaaatgtt ttagaagtag aggtgtacta ttctagttcc
       61 aatctactat ataaatgaaa accttagctg tttggccaag gttcatttct tctatgcaag
      121 ttcttctctt ttcttatctg ggttccagat gaagcttgcg ataaagctaa agatgatggt
      181 taggatagcg aggataatag caaggatgag ggcagggatg cggataaacc accagagtgg
      241 atttggtttt ttatcattgt gccattgttt cgtttcttcg tccagacgtt ggaattctgt
      301 ttgaatacga ttggcgactg tttcaatgcc ttcatcattc attttcttga tatctgagat
      361 atcgattgga tttccaaagt tcatatcgac acgttcacgg ctaatcaagc ccttcaaagt
      421 catgggaccg gtgtaggtaa ccggcatgat acggaccttg gccattttgg caatcagtgc
      481 tgcgcccccc ttgacatcgt ttgagtggcg gctaccactt ggaaacatga tgagagagcg
      541 gtcacttttt ttgagaacgt tgataggata tttgatggct gaggcgctgg gattttcacg
      601 gtcgatggga aaggcgccac acatacgaat ccaccaacca aagatacggt tggtaaagag
      661 ttcttttttt gccataaaga tgaactgttt tggcttggtc gcaaaggcca tataaacagg
      721 atcccaccag gtacggtgag gcgcaactaa aatataattt tcatcttgat taggaatttt
      781 atcagtatta tgatagtgag cattgccatt gatggaccat aagagcaata caactaatcc
      841 acgcaaataa gtataaaaca tgcgatctcc ttcgattgtt ttcttgttat tattatacct
      901 tatcaaagga gggctggcaa acttttccct tgactagata catatttagg atgaaattag
      961 aattctgtta aaaaaaatga tataatagaa tttatggata aaaataagat tatgggatta
     1021 acccaaagag aagtcaagga aagacaggct gagggtttgg tcaatgactt taccgcatca
     1081 gccagtacca gcacttggca aatcgttaaa cgaaatgtct ttaccctttt taacgctttg
     1141 aactttgcca ttgctttggc tcttgccttt gtgcaggctt ggagcaatct ggtcttcttt
     1201 gctgttatct gctttaacgc tttttctggg attgtgaccg agctacgagc caaacacatg
     1261 gtggacaagc tcaatctcat gaccaaggaa aaggtcaaaa ccatccgtga tggtcaggaa
     1321 gttgctctta atcctgaaga attagtgcta ggagatgtca ttcgtttgtc tgcaggagag
     1381 cagattccta gtgatgcctt ggttttggaa ggctttgcgg aagtcaatga agccatgtta
     1441 acgggagaaa gtgatttggt gcaaaaggaa gttgacggct tacttttgtc aggaagtttc
     1501 ctagccagtg ggtcagtttt atctcaagtt caccatgtcg gtgcagacaa ctatgctgcc
     1561 aaactcatgc ttgaggctaa gaccgttaaa cccatcaact cccgtatcat gaaatcgctg
     1621 gacaagttgg ctggttttac tgggaagatt atcattccct ttggtctggc tctcttgctg
     1681 gaagccttgc ttttaaaagg cctgcctctc aagtcatccg ttgtaaactc gtcgacagct
     1741 cttttgggaa tgttgcctaa gggaattgcc cttttgacca ttacttcgct cttgactgca
     1801 gtgattaagt tgggcttgaa aaaggtcttg gtgcaggaga tgtactctgt tgagaccttg
     1861 gcgcgcgtgg atatgctctg tctggacaag acgggtacca tcacccaagg aaagatgcag
     1921 gtggaggctg ttcttccgtt gatggaaacg tatggtgaag aggctattgc cagcatcttg
     1981 actagctaca tggcccatag tgaggataag aatccaactg cccaagccat tcgccagcgt
     2041 tttgtgggag atgttgctta tcctatgatt tccaatcttc ccttctcgag cgaccgcaag
     2101 tggggggcta tggagttaga aggcttgggg acagttttct taggggcgcc tgagatgttg
     2161 ctggattctg aagtcccaga agccagggag gccttggaga gaggatcacg tgtcttggtc
     2221 ttagctctca gtcaggagaa attagaccat cacaaaccac agaaaccatc tgatattcag
     2281 gctctagcct tgctggaaat cttggactcc attcgagagg gagcagcaga gacgctggac
     2341 tatctccgtt ctcaggaggt aggactcaag attatctctg gtgacaatcc agttacggtg
     2401 tccagcattg cccagaaggc tggttttgcg gactatcaca actatgtaga ttgctcaaaa
     2461 atcaccgatg aggaattgat ggccatggcg gaggagacag ctattttcgg acgtgtttcc
     2521 cctcatcaaa agaaactcat catccaaacg ttgaaaaaag cgggtcatac aacggctatg
     2581 acaggggacg gggttaatga tatcttggcc cttcgtgagg cggattgttc tatcgtgatg
     2641 gcggaggggg atccagcaac ccgtcagatt gccaatctgg ttctcttgaa ctcagacttt
     2701 aatgatgttc ctgagattct cttcgagggt cgtcgcgtgg tcaataacat tgcccacatc
     2761 gccccgattt tcttgataaa gaccatctat tccttcctgt tagcagtcat ctgtattgcc
     2821 agtgctttac taggtcggtc agagtggatt ttgattttcc ccttcattcc gatccagatt
     2881 accatgattg accagtttgt ggaaggtttc ccaccattcg ttctgacttt tgagcgaaat
     2941 atcaaacctg ttgagcagaa tttcctcaga aaatccatgc ttcgtgccct accaagcgct
     3001 ctcatggtcg tctttagcgt cctgtttgtg aaaatatttg ggagtagcca aggttggtct
     3061 gagttagaaa tctcaactct cctctattat ctcttggggt caattggttt cttatccgta
     3121 tttagagcct gcatgccatt taccctatgg cgtgtcctct tgattgtttg gtcagtagga
     3181 ggtttcctag ccacagctct cttcccaaga atccaaaaac tgcttgaaat ttcaacctta
     3241 acaggacaaa cattacctgt ttatggtgtc atgatgttgg tctttaccgt gattttcatc
     3301 ctgaccagtc gctatcaagc cagaaaataa agaaaggctg caatctgtgg attgcagttt
     3361 ttttaggtac aagattgcca gtcgaaatgt ggtataataa gaggtaatag agttttggaa
     3421 agtgagagaa gatgatttca aagagattag aattggtagc ttcctttgtg tcacaggggg
     3481 ctattttact agatgtggga agtgaccatg cttatctgcc tatcgagttg gttgagagag
     3541 gccaaatcaa aagcgctatt gcaggtgagg tggtggaagg tccctatcag tctgcggtta
     3601 aaaatgttga ggctcacggc ctaaaggaga aaatccaagt ccgtttagcc aatggcttgg
     3661 cagcttttga agagactgac caagtgtctg tcattaccat tgctggcatg ggtggtcgtt
     3721 tgattgctag gattttagaa gaaggtttgg ggaagttagc taatgtagag cgtttgatcc
     3781 tccagcccaa taatcgtgaa gacgacttgc gtatctggct acaggatcat ggattccaga
     3841 ttgtagcaga aagcatttta gaagaagctg gaaagtttta tgagattttg gtggtggaag
     3901 caggacaaat gaagctatca gccagtgatg ttcgctttgg tcccttcttg tccaaagaag
     3961 tcagtccagt atttgtccaa aaatggcaaa aagaagctga gaagctagag ttcgccctcg
     4021 gacaaatccc agaaaaaaat ctggaagaac gtcaagttct agtagataag attcaagcta
     4081 tcaaggaggt gctccatgtt agcaagtgaa gtgatccaag cttatgaagc cttttgccct
     4141 caggaatttt ctatggaggg agacagccgt ggtctgcaaa ttggcacttt agacaagggt
     4201 atccaaaggg tcatggttgc cctcgatatt cgtgaagaga cggtggcaga ggctattgaa
     4261 aagggtgtgg acttgattat cgtcaagcac gcgcctatct ttcgtcctat caaggacttg
     4321 cttgccagcc gtccgcaaaa tcagatttac atcgacctga ttaagcatga tatcgcagtt
     4381 tatgtcagcc ataccaatat tgatatcgtt gaaaatgggc tcaatgactg gttttgtcag
     4441 atgctaggaa tcgaggagac gacttatctg caggaaacag gtccagaacg tggaattgga
     4501 cgtattggga atattcagcc tcagacattt tgggaattgg cccaacaggt caagcaagtc
     4561 tttgacctag atagccttcg aatggtgcat tatcaagaga atgatttgca gaagcctatt
     4621 tcaagagtag caatttgtgg tggaagcggg cagtctttct ataaggatgc tttggcaaag
     4681 ggggcagatg tctatatcac tggtgatatc tactaccata ctgctcagga tatgctgtct
     4741 gatggcttgt tagcattgga tccaggtcac tatatcgaag tgctttttgt ggaaaaaatc
     4801 gcagcactcc ttactcaatg gaaagagaaa aaaggctggg aactagagat tttacctagt
     4861 caagcatcga ccaatccttt ccgtcatatc tagttagaaa gtgaagacaa tgaaaaaagt
     4921 tgccattatt ggagcaggaa ttgtgggagc aacagctgcc tactacctct cgagagaaag
     4981 tgacttagag gtgaccgttt ttgaccatga gcaaggtcaa gccaccaagg ccgcagcagg
     5041 aattatcagt ccttggtttt ccaaacgccg taataaagcc tggtacaaga tggcgcgctt
     5101 gggggctgat ttttatgtgg atttattagc tgatttagag aaatcaggac aagaaatcga
     5161 cttttaccag cgttcgggag tctttctctt gaaaaaggat gaatccaagt tggaagaact
     5221 ctatcaactg gctctccagc gcagagaaga atctcccctg ataggccagt tagccattct
     5281 ggatcaagca tcagctaatg aattattccc tggcttgcag ggattcgaca acttgctcta
     5341 tgcttctggt ggagcgagag tagatggcca actcttggta actcgtctgc tagaagccag
     5401 tcatgtcaag ttggtcaaag aaaaagtgac tctgacactc ttatcatcag gctaccagat
     5461 tggcgaagag gtgtttgatc aggttatttt ggcaacggga gcttggttgg gggacatgtt
     5521 agaaccttta ggttatgaag tggatgtccg tcctcaaaaa ggacaactac gagattatca
     5581 gcttgcccaa gacatggaag attaccctgt tgtcatgcca gaaggggagt gggatttgat
     5641 tccctttgca ggtgggaaat tatccttggg cgctacccat gaaaatgaca tgggatttga
     5701 tttgacggta gatgaaccct tgctccaaca aatggaggag gcggccttgc ctcattaccc
     5761 agttttagct agagtgactt caagggctga gcgtgtggga atccgtgcct ataccagtga
     5821 tttctctccc ttctttgggc aggtgccaga attggcaggt gtctatgcag ccagtggact
     5881 aggttcatca ggcctcacaa ctggtcctat cattggttac catctagccc aactgatcca
     5941 agacaaggag ttgaccttgg accctctaaa ttacccaatt gaaaactatg tcaaacgagt
     6001 aaaaagcgaa taatactcaa tgaaaatcaa agaacaaact aggtaactag ccgcgggtta
     6061 ctcaaagcac tgctttgagg ttgtggatag aactgacgaa gtcagctcaa aacactgttt
     6121 tgaggttgtg gatagaactg acgaagtcag taaccatacc catggcaagg cgacgttgac
     6181 gtggtttgaa ttggattttc gaagagtata agcattttac tgaaatttta tcaggtagtt
     6241 taggatggca aatgacattc cctgtcaaaa atggtaaaat aagaaaaaat aatctgagaa
     6301 tcgaggaaaa aagatgcaag aaaagatttt ggtaactggt ggtgccggtt ttattggaac
     6361 ccacactgtt attgaattga tccaagcagg ccatcaagtt gttgtggtgg ataatcttgt
     6421 caatagcaat cgtaagagtt tagaagttgt tgaaagaatc acaggagttg agattccttt
     6481 ctatgaggca gatattcgtg acacagctac cctcagagat attttcaagc aggaagaacc
     6541 gactggtgtc attcactttg ctggtttgaa ggctgttggc gaatcaacac gtatccctct
     6601 tgcctactat gacaacaata tcgctggaac tgtcagcctt ttgaaagcca tggaagaaaa
     6661 caactgtaaa aacatcatct tcagttcttc tgcgacagtt tacggggatc cgcacacagt
     6721 gcccatcttg gaagatttcc cactttcagt gaccaaccca tacggtcgta ctaagctcat
     6781 gctagaggaa attttgactg atatttacaa agcagactca gaatggaatg ttgtcttgct
     6841 tcgttacttt aacccaatcg gagcccatga gagtggtgat ttgggagaaa atccaaacgg
     6901 tattccaaac aatctcttgc catatgtgac tcaagtagcc gttggaaaat tagagcaagt
     6961 gcaagtgttt ggagacgatt acgatacgga agatggaaca ggtgttcgtg actatatcca
     7021 cgttgtcgat ttggctaagg gtcacgttgc agctttgaaa aaaatccaaa aaggttcagg
     7081 actaaacgtt tataaccttg gaactggtaa aggttactca gttcttgaaa ttatccaaaa
     7141 catggaaaaa gcggtgggcc gtcctattcc ttaccgcatc gtagaacgtc gcccaggtga
     7201 tatcgctgcc tgctactcag acccggcaaa agctaaagca gaactcggtt gggaagcaga
     7261 actcgacatc acccaaatgt gtgaagacgc atggcgttgg caaagcaagc atccaaatgg
     7321 atttgaagac taagatgatg atttcaatca tcgtcccttg tttaaacgaa gaggaagtac
     7381 ttcctctttt ttatcaggct ctggaagctt tacttccaga tttggaaaca gaaatcgagt
     7441 atgtctttgt cgatgatgga tcaagtgatg ggaccttgga actcttaaag gcctatcggg
     7501 agcaaaatcc ggcagtccat tatatttctt tctctcgaaa ttttggcaaa gaagcagccc
     7561 tttatgcagg cttgcaatat gcgacaggag atttggtggt ggtgatggat gcagacctcc
     7621 aagatcctcc tagtatgttg tttgagatga aaaatgtact agacaaaaat gtagacttgg
     7681 actgcgttgg gacacggaga actagtcggg agggagaacc cttctttcgc agtttctgtg
     7741 ctgttctctt ttatcgcctc atgcaaaaaa tcagcccagt agctctgccg tcgggtgtcc
     7801 gtgattttcg tatgatgaga aggtctgtag tcgatgccat tttaagcttg accgagtcca
     7861 atcgtttttc aaaggggctc ttcgcctggg tgggtttcaa aacctactat ttggactatc
     7921 caaatgtcga aaggcaggct ggcaagacca gttggagttt taggcaactc tttttttact
     7981 ccattgaagg gattgttaat ttttcagatt tccctttgac tatagccttt gtagctggtc
     8041 tcctatcttg ttttctttct ctgctgatga ccttttttgt tgtggttcgg accctcattt
     8101 tgggcaatcc gacatctggt tggacctctc tgatggctgt tattctcttt cttggaggca
     8161 ttcaactctt gaccattggg attctcggta agtatatcag taagatttat ttagagacta
     8221 aaaaaagacc actttatctt atcaaagaaa aaagtgacct tcctgatttt acagaaaaaa
     8281 taaagtgaaa agactataat tttacatgga aatgtgctaa actagaggga gtggattatc
     8341 gccattgatt taggcttcct ggtttccaat cagggcgcga gttgggcaat ttttaacagc
     8401 ctctaagaca tcctgactag gagaaatttc tttttccagt tggtcagggt catcgtaaaa
     8461 acgcacgatt ccattatcgt ggtaatcaaa taaatcagaa taagtttggc aaagtccaca
     8521 ggcgatacat cgttcaggta taagtgtgat tttcatgttc atatttatat tgtaataaga
     8581 aaagtaaaaa aaaacaagga gtaaggtatg gcaaaagaac cgtggcaaga agatatttat
     8641 gatcaagaag aatcaagagc agggcgtcgg catcgaaacc acggaggggc tgataggatg
     8701 gctaatcgta ttttgacgat cctagctagt attttctttg taattgtggt ggtgatggtc
     8761 atcgttctca tctatctatc atcggggggg agtaatcgca cagcagcctt aaaagacttt
     8821 catgattctg atgcaagtgt agtacaaatc tcatcttcaa gcagttctca gcctgagcag
     8881 agttcagagc cagaatctac ttctagtagt tcagaagaag ctgctaatcc tgaaggaacg
     8941 attaaagttc tcgcaggaga aggggaagca gctattgccg ctcgtgcagg aatctccatt
     9001 gctcagttag aggccttgaa tcctgggcac atggctacag gatcttggtt tgctaatcca
     9061 ggtgatgtta taaaaataaa ataggagccg atatgaaaac aattcaaatt gctattgatg
     9121 gtcctgcttc cagcggtaag agtacggtcg caaagattat tgctaaggat tttgggttca
     9181 cctaccttga tacaggagct atgtatcgtg cagcgaccta tatggctctt aagaaccaat
     9241 taggagttga agaagtcgaa gcccttctag ccttgttgga ccagcatcca atcagctttg
     9301 gacgttcaga aactggagac cagcttgttt ttgtaggaga tgtggatatt acccatccta
     9361 tccgtgaaaa tgaagtgacc aatcatgttt ctgctattgc agcaattcct gaagtgcgtg
     9421 agaaactggt ttctctccaa caagaaattg cccagcaagg cgggattgtc atggatggtc
     9481 gcgatattgg aactgttgta ttgccacaag cagaattgaa aattttccta gtagcttctg
     9541 ttgatgagag agcagagcgt cgttacaagg aaaatattgc caagggaatt gaaacagacc
     9601 ttgaaaccct aaaaaaggaa attgctgcgc gtgactacaa ggatagtcat cgtgagactt
     9661 ctcctctcaa acaagcagag gatgctgtct accttgatac aactggtttg aacattcaag
     9721 aagtagttga aaaaatcaaa gcagaagctg aaaaaagaat gtaaatgtag aaaagccgat
     9781 agattgatat cggttttttt ctaaatttgt caaaatgctg attttagggt ataatagttg
     9841 ctgttcgaga aattttgatt ttcaaagaat agtgaatgat gataaggaga aaccatgaac
     9901 aatttaccaa attgtccaaa atgtaactca gagtatgtct acgaagacgg tgccctactg
     9961 gtttgcccag agtgtgctca tgagtggaat cctgctgaag ttgcagaagt agaagaaggt
    10021 cttgtcgcta tcgatgccaa cggaaataaa ttgactgatg gtgatacagt aactctcatc
    10081 aaggacttga aagtaaaagg tgcgccaaaa gatttgaaac aagggacgcg cgtgaaaaat
    10141 atccgcatcg tagaaggcga tcacaatatc gactgtaaga ttgatggttt tggtgccatg
    10201 aaacttaaat cagagtttgt gaggaagatt taagcatgtc aaaacactat aaacttgtat
    10261 tttatagccg tatcttcttg tttctagcgg cttttacggg agtttatctt gaaattacta
    10321 ggcatggtgg ttttgggatg cttctctatt acacggttct gtccaacctc ttggtaacta
    10381 tttttaccct ttatcttcta aaggttatga gccgtgtagg tgaaaattgg caaaggccaa
    10441 gtctcttgcg cttaaaaggt ggggtcacca tgagtatcat gattacctgt gtgatttacc
    10501 atttcctctt ggcgcccatt gcgactaatt tctataccct agaaaatttc ctttgccact
    10561 atatcgttcc catctggttt ttagcggata ccctcttttt tgacaaacag ggtcaataca
    10621 agatttggga tccagcagtg tggaccattt taccctttct gtatatgatg tttgctcttt
    10681 ttaatggctt ggttctaaaa ctcaatattc caaatgccaa ggataatcct ttcccttact
    10741 tctttttgaa tgtgaacaag ggttggaatg ttgtgtttaa gtggtgtctg attatctttg
    10801 ttgcctatat ggtagcagga tttattttct actttatcaa gcaaatcaag agaaagtcat
    10861 cctaatactc ttcgaaaatc tcttcaaacc acgttagttt ccatctgcaa cctcaaaaca
    10921 ctgttttgaa caacctgcgg ctagctttct agtttgctct ttgattttca ttgagtatga
    10981 gatacaaggg attcattttc gaatttaaga aggagtctac aaaccaatga ggcttcttct
    11041 tttcttgctt atttgataac tatcaaaaaa gtagaagatt aagagaaata tagaaagaga
    11101 tttcatgaaa caatttttag aacgggccag cattttggct ctctccctcg ttttgattac
    11161 ctccttttcc atttcgagtg ccctaccagc catgtttgac tattatcagg gttattctaa
    11221 ggaacaaatt gagctcttgg tgagcttgcc ttcctttgga atcatgatga tgttactgct
    11281 aaatggtttc ttagaaaaaa tatttcctga gcgcttacag attagtttgg gcttgctgat
    11341 tttatcattg agcggtacag ctcccttctg gtaccaagcc tatccctttg tctttggaac
    11401 acggcttctc tttggtttgg gtcttgggat gatcaatgcc aaggccattt ctattatcag
    11461 tgaacgctac caaggaaaaa ggcgaattca gatgttaggg ctacgcgctt ctgcagaggt
    11521 cgttggagct tctctcatta ccttggccgt cggtcagttg ttggcctttg gttggacagc
    11581 tatctttcta gcctatagtg ctggattttt ggtgatgccc ctttatctgc tctttgtccc
    11641 ttatggaaaa tcaaagaaag aagtcaagaa aagagcgaag gaagcaagtc gtttaactcg
    11701 agaaatgaaa ggcttgattt ttaccttagc tatcgaagcg gcagttgtag tttgtaccaa
    11761 tacagctatt accatccgta ttccaagttt gatggtggaa agaggattgg gggatgccca
    11821 gttatctagt tttgttctta gtatcatgca gttgatcggg attgtggctg gggtgagttt
    11881 ttctttcttg atttctatct ttaaagagaa actgctcctc tggtctggta ttacctttgg
    11941 cttggggcaa atcgtgattg ccttgtcttc atccttgtgg gtggtagtag caggaagtgt
    12001 tctggctgga tttgcctata gtgtagtctt gacgacggtc tttcaacttg tctctgaacg
    12061 aattccagct aaactcctca atcaagcaac ttcatttgct gtattaggct gtagtttcgg
    12121 agcctttacg accccatttg ttctaggtgc aattggctta ctaactcaca atgggatgtt
    12181 ggtctttagt atcttaggag gttggttgat tgtaatctct atctttgtca tgtacctact
    12241 tcagaagaga gcttaggatt gattcctaag tttttctttt gatactcaat gaaaatcaaa
    12301 gagcatagtt gattgagttt ggaatagtac gctgtagctg ctaaaatatt tctagaaatt
    12361 aatttgactt ttctaataga gttattcata tcttatttca atctactata gaaagctagc
    12421 cgcaggttgc tcaaaatagt gttttgaggt tgcagatgga aactgacgtg gtttgaagag
    12481 attttcgaag agtatgagat ttttataccc atacaatatt tgttttaggt ccttgtttac
    12541 agactaattt cttgataaaa tagaggttat gacgagatat aaagcaacta tttcctatga
    12601 tggttatgcc tttgctggct ttcagcgcca gtctcatgcg cgtagcgttc aggaagaaat
    12661 tgaaaaaacc ttgaccagat taaataaagg gcaaaccatt actgttcacg gtgctggtag
    12721 gacagatagt ggggttcatg ccctgggaca ggtcattcat tttgacctgc cttatcagat
    12781 ggatgaggag aaactccgtt ttgccttgga tacccagtct cctgaagata ttgatgtgat
    12841 ttcgattgag cttgtggcag atgattttca ttgccgttat gccaaacata gcaagaccta
    12901 tgagtttatt gtggatagag gacgtcccaa aaatcctatg cgccgtcact atgccaccca
    12961 ctttccctac ccactcgatg tggaacgaat gcagattgca atcaaaaagc tagagggaac
    13021 ccatgatttt accggtttta cagcctctgg gactagtgta gaggataagg ttcgcaccat
    13081 cacagaagct agtttaatag tcgatgagac aggacaattt ttgaccttta ccttttcagg
    13141 aaatggtttc ttgtataaac agattcgcaa tatggtgggg actcttctca aaatcggtaa
    13201 caaccgcatg ccagtagagc agattgatct catcttggag aagaaggaca ggcaacttgc
    13261 aggtcccact gcagcaccaa atggtttgta tttaaaggag attcgttatg aagaataatc
    13321 gtattttagc actttctgga aatgatattt ttagtggtgg tggactgtca gctgatttgg
    13381 ctacctatac cttgaacggc ttgcatgggt ttgtagcagt gacttgtttg acagccttga
    13441 cagaaaaagg atttgaagtc tttccaactg atgataccat ttttcaacat gaattagata
    13501 gcttacgtga tgtggaattt gggggaatta agattggtct tctccctact gtcagtgtgg
    13561 ctgagaaggc cttggacttt atcaaacaac gcccaggagt acctgtggtg ttggatcctg
    13621 tcttggtctg caaggaaacg catgatgtag ctgtcagtga gctctgccaa gagttgattc
    13681 gctttttccc ttatgtcagt gtgattacgc ctaatctccc agaagcagaa ttattatccg
    13741 gtcaggaaat taaaaccttg gaagacatga aaactgcagc gcagaaattg catgatttag
    13801 gagcgccagc agtcattatc aagggaggca atcgtcttag tcaggacaag gctgtggatg
    13861 tcttttatga tggacagacc tttactatcc tagaaaatcc agttatccaa ggccaaaatg
    13921 ctggtgcagg ttgtaccttt gcctctagca ttgccagtca cttgattaaa ggtgataaac
    13981 ttttgccagc agtagaaagc tctaaggctt tcgtttatcg tgctattgca caagcagatc
    14041 agtatggagt aagacaatat gaagcaaaca aaaacaacta aaatcgccct tgtatcccta
    14101 ttaaccgccc tttctgtggt tctaggttat ttcttaaaaa tcccaacacc tacaggaatt
    14161 ctaactcttt tagatgctgg tgtcttcttt gcggcctttt actttggtag tcgtgaagga
    14221 gcggtagtcg gaggactagc aagtttcttg attgacctct tatcaggcta ccctcagtgg
    14281 atgttcttta gcttggtcaa ccatggcttg cagggatttt tcgcaggatt taaaggaaaa
    14341 agtcagtggt taggccttat tttagcaact attgccatgg taggaggcta cgccttgggt
    14401 tctactttga tgaatggctg ggcagcagcc ctcccagaaa ttctaccaaa tttcatgcaa
    14461 aatatggtag ggatgattgt aggatttatt cttagtcaaa gtatcaagaa gattaagtaa
    14521 tactcttcga aaatctcttc aaaccacgtc agcttccatc tgcaacctca aaacactgtt
    14581 ttgagcagcc tgaggctagc tttctagttt gcactttgat tttcattgag tataaagagg
    14641 ttgagtaaaa agtatttcaa ataagaaaaa cgcatagtat caggtgttga atgaactgcc
    14701 ccccaaaagt tagacagaaa aaatctaact tttggggt
//
LOCUS       DAVLBE010000043        14633 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.043, whole genome shotgun sequence.
ACCESSION   DAVLBE010000043 DAVLBE010000000
VERSION     DAVLBE010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14633)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14633)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14633
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.043"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(778..1647)
                     /locus_tag="VXB91_001496"
     CDS             complement(778..1647)
                     /locus_tag="VXB91_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEV0470925.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTENPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKAIEAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIVA
                     AIAAVAVFKFLYL"
     gene            complement(1871..2392)
                     /locus_tag="VXB91_001497"
     CDS             complement(1871..2392)
                     /locus_tag="VXB91_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEV0470926.1"
                     /translation="MVPKTATSTETKTITRIIHYVDKVTNQNVKEDVVQPVTLSRTKT
                     ENKVTGVVTYGEWTTGNWDEVVSGKIDKYKDPDIPTVESQEVTSDSSDKEITVRYDRL
                     STPDKPTPDPGTPKTETPVNPDPEVPTYETGKREELPNTGTEANATLASAGIMTLLAS
                     LGLGFFKKKEDEK"
     gene            complement(2350..3456)
                     /locus_tag="VXB91_001498"
     CDS             complement(2350..3456)
                     /locus_tag="VXB91_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HEV0470927.1"
                     /translation="MNIILIAKLLRENTNTKANALNNGWARSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVGSGDSKLGKGGYFSTGDVLLGKDVVSYTVQVFSENNE
                     RVGVNTQSHRVQYNLPILADFSVIQDTVEPSRTVVEKIIPKLNIPEEEKGKITEEIKK
                     KKKTSELAELISENVKVRYVDEQGRLLSLKNDTGIGEKESDGTYITNKKQLIGTSYNV
                     TDKKLSSMTTTDGKYYTFKEADTNSASLTGNIVSEGRTVTLVYRESEAPTTATVTANY
                     YKEGSQEKLAESVIKADLAIGSEYTTESKTIEGKTTTEDKEDRVITRKTTYTLVATPA
                     NAYQKTVQQLTITTVRMLRKQWFPKQQPLLRRRL"
     gene            complement(3567..3821)
                     /locus_tag="VXB91_001499"
     CDS             complement(3567..3821)
                     /locus_tag="VXB91_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0470928.1"
                     /translation="MLNVDQDFMSISKSNKSGSDWKKTFTVRTTNRLANDLNNVLKQA
                     DKDTPNTPTWLNSAASKAKDDDRAYKLLKTLIPGENYLSC"
     gene            complement(4161..4694)
                     /locus_tag="VXB91_001500"
     CDS             complement(4161..4694)
                     /locus_tag="VXB91_001500"
                     /inference="COORDINATES: protein motif:HMM:NF024751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HEV0470929.1"
                     /translation="MTSFKEQEPEKVAEFLDILDNLKDLPIVYIDETGIDRYLYRPYA
                     RAPRGEKVYKKISGRRFERTSIVAGQVDGEFIAPMIYKKSMTSDFFVEWFKTQLLPAL
                     KTPHVIVMGNASFHPKNILDELCIQDKHFFLPLPPYSPDLNPIEQAWAILKKKVTDLL
                     REVPTIFECLECFFKTR"
     gene            complement(4681..4896)
                     /locus_tag="VXB91_001501"
     CDS             complement(4681..4896)
                     /locus_tag="VXB91_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0470930.1"
                     /translation="MGKERCEQGHIERKKRVVKNRKIPLEELKAFVEAHPDAFLREIA
                     AHFDCALPSVWAALKYIKVTLKKDDEL"
     gene            complement(4863..5006)
                     /locus_tag="VXB91_001502"
     CDS             complement(4863..5006)
                     /locus_tag="VXB91_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tnpB"
                     /protein_id="HEV0470931.1"
                     /translation="MAYSTDFKQRALDYIKEGHSHVEAAKFFGVGVRTLFTWEKKDVN
                     KDT"
     gene            5240..6958
                     /locus_tag="VXB91_001503"
     CDS             5240..6958
                     /locus_tag="VXB91_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEV0470932.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDVEYLKEVKDVNI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPTEWNATAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKITNIEAE
                     INAFVK"
     gene            7069..7416
                     /locus_tag="VXB91_001504"
     CDS             7069..7416
                     /locus_tag="VXB91_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEV0470933.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     AGTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFIHITDGQINVRCDS
                     SMSAQEIKDFAGL"
     gene            complement(7695..8531)
                     /locus_tag="VXB91_001505"
     CDS             complement(7695..8531)
                     /locus_tag="VXB91_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0470934.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPEILKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTTLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(8544..9173)
                     /locus_tag="VXB91_001506"
     CDS             complement(8544..9173)
                     /locus_tag="VXB91_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV0470935.1"
                     /translation="MLELRNINKVFGDKQILSNFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLENLTLSPVKT
                     MGMKQEEAEKKASGLLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            complement(9183..9824)
                     /locus_tag="VXB91_001507"
     CDS             complement(9183..9824)
                     /locus_tag="VXB91_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV0470936.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
     gene            complement(9970..11199)
                     /locus_tag="VXB91_001508"
     CDS             complement(9970..11199)
                     /locus_tag="VXB91_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HEV0470937.1"
                     /translation="MNNSQQMLQALEEQDLTKAEYYFAKALENDSSDLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLVL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLMLGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLDTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLAAKEDAEDTEEILLRLATIYLEQERYEDILDLQSEEPENLLT
                     KWMIARSYQEMDDLDTAYEHYQELTGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            complement(11189..12355)
                     /locus_tag="VXB91_001509"
     CDS             complement(11189..12355)
                     /locus_tag="VXB91_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEV0470938.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFLAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVIFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            12499..13512
                     /locus_tag="VXB91_001510"
     CDS             12499..13512
                     /locus_tag="VXB91_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HEV0470939.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FVRMQVISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPDQKFLIVVHQDSDNATVFKRNCDNGRLAELSNEFHVPEAVCIR
                     FAP"
     gene            13652..14633
                     /locus_tag="VXB91_001511"
                     /pseudo
     CDS             13652..14633
                     /locus_tag="VXB91_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         4480 a         3141 c         2561 g         4451 t
ORIGIN      
        1 taaaaattta actaattaat agaaagtact aaatagactt atccttcaag gagttttcag
       61 cattatccat ccactcactt gctgaaaatg taaacagtct ctggtttata tagtaaaatg
      121 aaacaagaat agagcaaatc gatcaggaca gtcaaatcga tttctaacaa tgttttagaa
      181 gtagatgtgt actattctag tttcaatcta ctatacaacc tcaaaactgt gttttgaaca
      241 acctgcggct agcttcttag tttgcccttt gattttcatt gagtataaaa ttgcagataa
      301 aacgataaca atcataggac tcagcagagt caatgtaggt cgaagaatac ccccctaatc
      361 gcttatttta tagcaaaatg aaatagaaac tgaacatttt gttgaggaag gtaaatcaat
      421 tcctcacaat gtttgagaaa gaagggagga ctattccaac ttcaacccac tataaagcag
      481 acttacaaga tagggaaccc atctccgata atatatagta gaatgaaaac tgcacaattt
      541 gattggagaa ttcaaaccaa tttctcacaa tgttttagaa acaagggtct attatttcaa
      601 ctgcaaccta ctatagtcca ttgaagctgg aatagcccac tgagacttct aaaccactgc
      661 tggagaggag tttgtttaga gtttctttca tttccctaaa aaatcaaaaa gagagaacca
      721 gtctgatcct ctcttattta tagatggtgc tcactcaaat gttaaaggag ctatttctta
      781 gagataaagg aatttgaata cagctactgc cgcaattgct gctacgatag gtgctactac
      841 tggtacccaa gaataccacc attttgaatc gcctttatgc tcaccaagaa ctgattttgg
      901 aaggaaagca tgaaggagac gtggtcccaa gtcacgggct gggttcaagg caggtcctgt
      961 aggtcctcca agtgatgtta ccaaagccat aacgaggaat ccaagtgcca agtgagccac
     1021 agaaagtcct gaagcagtgt gtggagccac ctgtgcttta atagccaagt cagaaaaatc
     1081 aactgtttgt cctgcttcta ttgccttttg tttcatgaat tgaagcactt cagcaccaaa
     1141 gaagttttta gtcaaaccaa gagctgcaaa gaacaaaaca aatgaaccaa caaactcatt
     1201 aatcaaacca ttgacagttg ctgcatagcg actttctttt gtaccatggt caatacttga
     1261 aatagttgag aaagttccca agatgttatt tgggttttca gttttcaagt agaatggacg
     1321 gtatgttgcc acaactaagg cttggccaaa gatagctccc aagacttgcg cgataatata
     1381 aggtaccact tgtgcccaag ggaaaagacc gctaactgca agccctagag tgaaagcagg
     1441 gttgatgtga ttcccagata cgttaccaaa catcaaggct gggatcataa cccccatacc
     1501 ataaccaaca gcgatgacga tccagccact ttggtgacct ttcgtacctt taagttcaac
     1561 gttggcaact gcaccattcc caagaatgat caaaatggca gttcccaaaa attcagtggc
     1621 atacttcagt gcccatgtga aatccatttg ctagattctc cttaaaattt tttagatatt
     1681 ccttatttta tcaattttta ccctatttag caactgattt ctggaaatat ttttaaaaaa
     1741 ataggattca tagtttccca gttcaacgga cttgtaagcg tttttattct tcacgaaaga
     1801 cctcgttctc aaaaccagga aaaaagccca catctgtgag cttttcctgg ttcctagatt
     1861 ctaaaatcta ttatttttca tcttcttttt tcttgaagaa tcctaatcct agactagcta
     1921 acaaggtcat gataccagca ctagccaagg tagcattagc ttctgtacct gtgtttggca
     1981 attcctctct cttacctgtc tcataagtcg gaacttctgg gtctggattc actggagttt
     2041 cagtttttgg agtacctggg tctggagttg gtttatctgg tgttgataaa cggtcatacc
     2101 ttaccgttat ttctttatca ctagagtctg acgtaacttc ttgtgattca actgttggaa
     2161 tatctggatc tttgtacttg tcaatcttac cagatacaac ctcgtcccag tttcctgttg
     2221 tccattcacc gtaggttaca actcccgtga ccttgttctc agtttttgta cggcttaagg
     2281 ttacaggttg aacaacatct tcttttacat tttggttcgt aactttatca acgtaatgaa
     2341 tgatacgcgt tatagtcttc gtctcagtag aggttgctgt tttgggaacc actgtttcct
     2401 caacattctc acggtagtaa tagtcaactg ttgcaccgtc ttctggtacg catttgcagg
     2461 agttgctacc aaggtgtatg ttgttttcct tgtgataact cggtcttctt tgtcctcagt
     2521 tgttgttttc ccttcaatag tttttgattc tgtggtatac tcagaaccta tcgctaaatc
     2581 agcttttata acagactctg ccaacttctc ttggctacct tctttatagt aattggctgt
     2641 tactgtagca gtggttggcg cttcgctttc tctataaact aaggtcactg ttctaccttc
     2701 gcttacaata ttcccagtta aacttgcaga atttgtatct gcttctttaa aagtataata
     2761 ttttccgtca gtagtagtca tgctactgag ttttttatct gtgacattgt agctggtacc
     2821 aatcagttgt tttttattgg taatgtaggt tccgtcactt tctttttctc caattccagt
     2881 atcatttttc aatgatagca aacgcccttg ttcatcaaca tagcgaactt tcacattttc
     2941 tgagattagt tctgccaatt ctgaggtttt tttctttttc ttgatttctt cggttatttt
     3001 ccctttctct tcttcgggaa tatttagttt tggaatgatt ttttcaacaa cggttcgtga
     3061 tggttccaca gtatcttgga tgactgaaaa gtcagctaga attgggagat tatactgaac
     3121 acggtgactt tgagtgttta ctcctactct ttcattattc tctgaaaata cttgtacggt
     3181 ataagaaaca acatcttttc ctaatagaac atccccagta gagaaatagc cgccttttcc
     3241 tagtttgcta tctccagagc ccacttcttt cctaatctta tcagatagtt ttttaccagt
     3301 cagtacattc gttcgcacaa tccctttgtc tacccctaca aagtgggaga actttttgaa
     3361 ctcttcagaa ccagatctag cccaaccatt attaagggca tttgcttttg tatttgtatt
     3421 ctctctcaaa agtttggcga ttagaattat attcatcggc acttagagtt gctgctatat
     3481 ctgactcttg aataccaact tccttactac catttctagc ggcagtatat gtgtatttat
     3541 ttgtttctac ttctagctga ttatccttaa catgataggt aattttctcc tggtataaga
     3601 gtcttcagta gtttatatgc tctgtcatca tctttagctt tagaagcagc tgagtttagc
     3661 caagttgggg tattaggagt atctttatca gcctgtttca agacattatt caagtcattt
     3721 gctagcctat tggttgtcct cactgtgaaa gttttcttcc agtctgaacc acttttatta
     3781 gacttagata tgctcatgaa atcctggtca acattcaaca caatatcgcc ttgtttttta
     3841 gcatcttccg ttgcttctgc ttcaaattga tcatggagtt tttgttgctc tggtgtatag
     3901 tttttttatt tacacgattt aatgtactat tttttatttt agtattaaga actccattaa
     3961 tacgattttt aaactctgct tcaaaaaatc ccttaatttg ttggtgcgca agttcaacat
     4021 tcaaaccttt cttatacaag tcttcattct aaacgatttc ggctacacgg tgaatggttt
     4081 gattgtatac cgtcttctct taaccagcag tatccttagt tttaatgact actcgatagg
     4141 ttcctttaga accgttatag tcatctagtt ttaaaaaagc attccaaaca ttcaaaaata
     4201 gttggaactt cccttaataa atccgtcact ttctttttca agatagccca agcttgctca
     4261 ataggattca aatccggtga ataaggtggt agaggtaaga aaaagtgttt atcttggatg
     4321 cagagttcat ccaaaatgtt cttgggatga aaactagcat tgcccatgac aataacatga
     4381 ggtgtcttca aagcaggtag gagttgcgtt ttgaaccact ccacaaagaa atcgcttgtc
     4441 atgcttttct tgtaaatcat gggagctata aactctccgt ctacttgtcc tgcaacaatt
     4501 gaagttcgct caaaacgacg tccgctaatc tttttataga ctttctcccc tctaggagcc
     4561 cgtgcataag gacgatagag gtagcggtcg attcctgttt catcaatata tacgattggt
     4621 aaatctttta ggttatccaa aatatcaaga aactcagcga ctttctctgg ctcttgttcc
     4681 ttaaagctcg tcatcttttt ttaaagtgac cttaatatac tttaaagctg cccatacgga
     4741 gggcagagca caatcaaaat gtgccgcaat ttcccgtaaa aaagcatctg gatgagcctc
     4801 tacaaaggct ttcaattcct ctaaaggaat ctttcggttt ttgacgactc gctttttcct
     4861 ctctatgtgt ccttgttcac atctttcttt tcccacgtga agagagttct gacgccaaca
     4921 ccaaaaaact tggctgcctc gacatggctg tgcccctctt tgatgtaatc taatgctcgc
     4981 tgtttaaaat cagtactata tgccatagct ttattataat atgcttgttt aaaactaagc
     5041 aactatatca atgttttgtt attagaagac ttactttttt tactgaaatc gaatttttcc
     5101 taacctcaac atcatataac cccaaaattc aatctgacct ggtttgaaga gatgttcgaa
     5161 gcagataagg ttttactaaa actaaaaaaa atgatataat caaactgatt aaatgtttta
     5221 aaaataaagg agaatttgaa tgtcttacca agaaaattac cagaaatggg ttgattttgt
     5281 ggagcttcct gactaccttc gtcaagattt ggaaaatatg gacgaaaaaa ctaaggaaga
     5341 tgccttctat acaaatcttg aatttggtac tgcaggtatg cgtggcttgg ttggtgctgg
     5401 tacaaaccgt atcaacatct acgttgttcg ccaagctact gaaggattgg ctcgtttgat
     5461 tgagtcaaaa ggtggaaacg agaaagaacg cggtgtagca attgcctacg atagccgtca
     5521 cttctcacct gagtttgcct ttgaatctgc ggcagttctt gctaaacacg gcatcaaatc
     5581 ttacgtattt gaaagccttc gtccgactcc agaactatca tttgcagttc gtcatctcaa
     5641 ctgtttcgca ggtatcatgg tcacagccag ccacaaccct gctccattta acggttacaa
     5701 ggtttacggt gaagacggtg gacaaatgcc tccacacgat gcggacgctt tgactactta
     5761 tatccgtgca atcgaaaacc catttgcagt tgaagttgct gatgtggaaa ctgaaaaagc
     5821 ttctggcttg attgaagtta tcggcgaagc tgttgacgta gaatacctta aagaggttaa
     5881 ggacgtaaac atcaacccag ccttgattga agaatttggt aaagacatga agattgtcta
     5941 cacaccactt catggtactg gtgaaatgtt ggctcgtcgt gctcttgccc aagcaggatt
     6001 tgactctgtt caagttgttg aagcgcaagc aactgctgac ccagacttct caactgtaac
     6061 atctccaaac ccagaaagcc aagcagcctt tgcccttgct gaagaacttg gtcgtcaagt
     6121 tggtgcagat gttcttgtcg caactgaccc agacgctgac cgtgttggtg ttgaagttct
     6181 tcaaaaagat ggtagctacc tcaacctttc aggtaaccaa atcggtgcta tcatggctaa
     6241 atacatcttg gaagctcaca aaaacgctgg aactcttcct gaaaatgccg ctctctgcaa
     6301 atctatcgtt tcaactgact tggtaacgaa gattgctgaa agctacggcg caactatgtt
     6361 caacgtcttg acaggtttca aatttatcgc tgaaaaaatc caagaattcg aagaaaaaca
     6421 caaccacact tacatgatgg gatttgaaga aagcttcggt tacttgatta aaccatttgt
     6481 acgtgataaa gatgccatcc aagccgttct tgtcgttgct gaacttgctg cctactaccg
     6541 ttctcgtggt ttgacacttg ctgacggtat cgaagaaatc tataaagaat atggctacta
     6601 cgcagaaaaa acaatctctg ttactctttc aggtgtcgat ggtgctgaac aaatcaaagc
     6661 gattatggct aaattccgca acaatgctcc aacagaatgg aacgcaacag ctatcactgt
     6721 cgtagaagac ttcaaggcac aaactgctac tgttgctgac ggtactgtta caaacttgac
     6781 aactcctcca agtgatgtgt tgaaatacac acttgctgac ggttcatgga ttgccgttcg
     6841 cccttcaggt acagaaccaa aaatcaagtt ctacattgca gttgtagggg aaaccaacga
     6901 agaatcacaa gctaagatta ctaacatcga agcagaaatc aatgcatttg taaaataaag
     6961 acctataaaa gatgagacca accaacctca tcttttttcg tatcaaatct aagcaatttt
     7021 agaaacttta tggcatacta gacttatcaa tgaaagcgag gtaatctcat ggaacaattt
     7081 ttagataaca tcaaagacct tgaagtcact acagttgtgc gtgcgcaaga agctcttgat
     7141 aaaaaagaaa ctgcaacctt ctttatcggt cgcaaaactt gcccttactg ccgtaaattt
     7201 gcaggtacat tgtcaggtgt cgtagctgaa accaaagctc acatttactt catcaatagt
     7261 gaagaaccaa gccaactcaa tgatttgcaa gcattccgct cacgttatgg aatcccaact
     7321 gtaccaggtt ttattcatat tacagatgga caaatcaacg tccgttgcga ctcttcaatg
     7381 tcagcacaag aaatcaaaga tttcgcagga ttgtaaaaaa tcagctaaca agtcttaaaa
     7441 tcacaaaaac gcataatgta aggtgcaaaa accttgatat tatgcgtttt attgttccta
     7501 aaacagttac atcagcattt cattacagaa cattttaatt ttggaagtca aatcaatttt
     7561 taacaatgtt ttagaaatca cagtgggcta ttccatattc aattatccag attcaatcgc
     7621 tattatcgtt ttcctagatt acaaaaaaaa ctacgttttg ctaatcaaaa cgtagtctca
     7681 gccactattt tatcttactg tccttctttt acttctttgg ttgctacatc ttctccaaac
     7741 catttttggc tgatttcttg gaacttgccg tccttgtaaa gactagaaaa agcttcattt
     7801 atcttcttaa ccaaggttgt atcttcctta cgggctccaa ccgcaaaagc ttctgtttct
     7861 agtccaactg taaagacatt ataatcgttt aaaacacctt ctgcttctaa ataatagttt
     7921 gcatagacac ggtcaatcaa tagaccatca attcgatcgt ttttcaaatc aatcaaggct
     7981 tcattaaagg tttggtattg attcgcttcc ttattagcga caatattctt caaaatttct
     8041 ggatttgctt caaagtccgc ataaccagat gaaccagctt gagctcctaa tgtctttcca
     8101 gtcatatcct ttgcagtcgt tataccagat gattttttcg taaccaatac ctgctcattc
     8161 ttcatatatg agttactgaa agccaccttt tcacggcgtt cgtctgtagc ggaatagcca
     8221 ttccaaatca gatcaatcgt tccttttgtc aattcagctt ctttcaaatc ccaatcaatc
     8281 ggttgccaat ttaccgtgat tccgtatttt tcaaaaacag ctgtagctaa atcaatatca
     8341 aatcctgcat aagaaccatc tttctgagca aatcccattg gaacaaaagt actatcaaat
     8401 ccaatagtaa tagacttgtt agactggtac tttgaccaat tatctccact agtttcgcta
     8461 gaatttttcc cacaagctac taagaacaaa gcagtcatca gactgactaa tacaagcatc
     8521 cattttttca tccatttttc ctcctattta ggttctactt tcaataatac atctgcgata
     8581 ttttcagcaa actgcaaatc atgggtaacc acaatctggg tcatcccaag ttccctattt
     8641 tgcaagatta gcttctccac ttccaaacgt aattctggat ccagggcaga agttggttca
     8701 tcgtagccaa tgatttctgg gtcaatcatc atagcacgcg ccaaagccac ccgctgcttt
     8761 tgcccaccag atagtgagaa aggataggcc tctgcgtgtc ctcctagtcc taactgttcc
     8821 aagagtccac tcgccttctt ctcagcctct tcctgcttca ttcccatggt cttcacaggc
     8881 gataaagtca aattttccag aactgataga tgaggaaata gttgaaaatc ttggaagaca
     8941 aatcctagta ggttgcgctt ctgcaattca tccagctcta aaggttgtcc attataaaag
     9001 atttgccctg aatcaatggt ttcaagaccc gcaagcatac gtaaaagagt cgtcttacct
     9061 ccaccagaag gtccaacgat agccaggatt tgcttttcag gaatacttag actgaaatta
     9121 gacaggattt gtttgtctcc aaagacttta ttgatatttc gtaattctaa catggcagcc
     9181 tcctatctat aataactata cttcttctca acttttttgg aaataattgt cacaatccca
     9241 atcaaaatca aataaatggc tcctgccaag aacataggaa ctagactagc atcgcggtta
     9301 gcagctgttc gactagccaa gataaggtct gaaattccga gagcatagac caaagaagta
     9361 tccttgacca aactcataac ttcattaaag acactaggaa gaacgatctt ggtcacttgg
     9421 ggcaagataa tatagcgcac tctgtcaaaa gggctaaact tcaagacctt ggcggcctca
     9481 tactgtcctc ttggaatagt gtcaattccc ccacggaaaa tttctgcaaa gtaagctgca
     9541 tagttgagaa caaaggcaat aatagctgca ggaaggcggt ctaaacgaat cccaatactt
     9601 gggagcacat aatagataaa aattagttgc aagagtaagg gggttcctcg cataacccag
     9661 atgtaaatgt taatcagata atggaggggc ttccaatgga cttgcaaggc aaaagcaatc
     9721 aaaacgccca agggaatcga aaatagcaag accagtgcaa agacctgtac agtcgtgctc
     9781 gcaccattca gtaaactcgg taatatctca aataaataag acatactgca cctcctaaaa
     9841 gtaattgttc ctattatagc atgaataaac aagattacca agtatttttg taaaaagatt
     9901 ctaccatata caaataaaaa ccgtagctat caaaagagat aaactacagt tctatatgtt
     9961 taaacattct tacaatctct caaacagttc ttgcatttgc acatcatctg gaaccagttt
    10021 taagtaagtg tgagcatgga cttttgcttc ttcaaaatgt cccaattcac gcaagagata
    10081 gatatagtgt tccagaaatt ctggattgtc cttcaaatct cctgtcaact cttgataatg
    10141 ctcataagca gtatccaaat cgtccatttc ttgataagaa cgagcaatca tccacttggt
    10201 caaaagattt tctggctcct cactctgcaa gtctagaata tcctcataac gctcctgctc
    10261 cagataaata gtggctaaac gaagcaagat ttcttctgta tcctcagcgt cttcttttgc
    10321 agcaagaaga taattttctg caccactagc atcatgcaat tcataagaaa attgtgaagc
    10381 agctagcaag aggcgagttt caaagggatt tttctctaat ccttgcttag cgatacgcag
    10441 ggcttcttga acttgatgtt ccttatgtaa agcctgactg tacccatact catagccttc
    10501 aaagtcagga gaaatggtat caagctgctt aaagtagagg gtggcttttt gatattcttc
    10561 ttgatcaaaa taaagactgg ccaactcaaa agctgttaag tcatcgtatt ctaactccag
    10621 ggctttttct aaaaactcag tagccgtttc aaatttccct aactgagcat aggcaaagcc
    10681 aattcgttga taggtggaaa tgcccgtttg ctcataaatc gagcgattat ctaactgggc
    10741 ataggcttga atagccgctt ggtaattttc caactcacta tccaactctg ccaaacccaa
    10801 catcaagaga gaatcctctg agtaggtcaa ggcctccaat aatttctcac gtgccacatc
    10861 tgtcaaacct tccagctggt aaaggtctgc cttcaaaacc aaagacgaga cataccagtc
    10921 actgtcagct tggatttcct caagataggt aaaggcttct tctatttgac catcctcgct
    10981 agcaattgca gctagattaa gatgaacctc tggaaaatcc tctacaattt tcaggtaaat
    11041 ttccttggcc tgaggataga aaccaatccc ttcaagataa gttgccaact catacagaag
    11101 atcacttgaa tcattttcta aagctttggc gaaataatac tcagccttag ttaaatcttg
    11161 ctcctccaaa gcctgtaaca tctgttgact attgttcact cttgacttcc tcaccctcta
    11221 attcatatag accactgact accttatacc attcgaaaat ggctgaaatg acaaccttag
    11281 cagaggcata aaccggaata ccaagtaaaa ctccccagat accaaacata gatcctgaag
    11341 ttaacaaaac aaagagaaca ttaatagggt ggatgtttaa ttgacttccc aaaatcaatg
    11401 gagagacaaa acggccttca atagtttgtt ctacgataaa gacaatcact actttcaaaa
    11461 gcatgactgg accagcaatc aaacccaata ctagagcagg aagcatggct agaaagctac
    11521 caagataagg gaccagattt aaaataccag cagtaacccc cagcgtaacc gcatagcgta
    11581 gaccaataat cttgaagaag atgataaata ttactgctac aataatagcc actgtcactt
    11641 gccctcgaac atagttggac aactgttgat tcacatctga taaaacttgt ccaacaggtt
    11701 ccttcaattt tcttggaatg aattgggtca aatagttacg caagcctttc ccatcacgca
    11761 agagataaaa gagcatgaaa ggaacgataa tcaaggcaac aatcacttga gaagctccac
    11821 taataaaggc actcacccag ttgactgcct gagatgaaac cttacttgcc aaaactgtag
    11881 cctggctaga aaaattggtc aaaacttgct ctaattgagg tctgaaatca tctggcaggt
    11941 gctgggctac caatccatta acaatcctat ctatatcttc taagtaaaca ggaacgtttc
    12001 ttgcaaaggt caaaacctga cgttgcagat ttggaatggc gactgccaag ccccaaatga
    12061 taaagagagc gatgataaca aagacaatag tgatagctat aacacgatta accttatgct
    12121 tctccatcca atcaacaata ggattcaaca aataatataa caaaccagac aaaatgactg
    12181 gcaacatcac aactgctaaa aaatctaaaa caggtgaaaa tagaaaacta atcttactta
    12241 aaataaaaag attcaatccc aataataagg ttactaaaaa taccgtaatt gccttgttat
    12301 ctaaaaacca cttgaaaaac caagataggc taaaatgttt ctctttttgc tccataaata
    12361 cttcctttct attgttctct cattatacca tttttgaaac aaaataactc ttttttaaag
    12421 tgcttacatc taattgaatg tctttaattt gcttgttttt gtgatataat agtcttatct
    12481 ttacacagag gtatagtaat gaaagaaact gtttattttg gaacttatac acgtcgtact
    12541 tctcaaggga tttacaaggc agactttgat acagaaactg gtcagctttc aaatctagaa
    12601 ctttttgcag ctgagccaag tccaacctac cttgcctttg accagcacca acatttatac
    12661 actgttggta gccaagacga taagggggga attgcagcct atcaaactga cgggactgtg
    12721 ttaaatcatg ttgttgaaga aggagctccc cactgttatg ttgctgtcga tgaaaagcgt
    12781 gatttggttt acgcagccaa ctatcacaag ggacaagtcc ttgtttataa acgccaggaa
    12841 gatggtagtc ttctacttag tgatatggat caacacagtg gccaaggtcc acatgaaaat
    12901 caagcttccc cccatgttca ctatacagat ttaacacctg accactatct agtgacctgc
    12961 gacttgggaa ctgaccaagt catcacctat gacctcgatc aagaaggaaa attatctaag
    13021 ctctatacct atcacagcaa gccaggagca ggctcacgcc atatcatttt ccataaccac
    13081 tataaaatcg cttatctcat ttgtgaactc aatagtacta tcgaagtttt aatctacgat
    13141 ggcgttggcg aatttgtacg tatgcaggtt atttcaactt taccagaagc ttacgaaggc
    13201 tttaatggaa ccgctgctat tcatctctct aaagacggta aatacctcta cgcttctaac
    13261 cgtggccatg attctatcgc agtatatacc atccttgcgg acggtagctt agagttatta
    13321 gaaatcgttc caacgcatgg tcagactcca cgtgattttg atttgacacc cgaccaaaaa
    13381 tttctcattg ttgtccatca agactctgac aatgcaactg tctttaaacg taattgtgac
    13441 aatggtcgtc tagcagaact ctccaacgaa ttccatgttc ccgaagcagt ctgcatccgt
    13501 tttgctcctt aaaacaccat aaaaaatggc tctataatat ttgtagtggg taaatcccct
    13561 atggatatta tggagcctat ttttgtgtag aaaaaaagtc ccataagatc tataatgaaa
    13621 agcgatcaaa caactcatta gaaagattca tatggaacaa ttacatttta tcacaaaact
    13681 actcgatatc aaagacacaa atatccaaat tatagatgtc gtcaataggg attcacacaa
    13741 agaaatcatc gccaaactgg actacgacgc accatcttgc cctgagtgcg gaaaccaatt
    13801 gaagaaatat gactttcaaa aaccttctaa aattccttat cttgaaacga ctggtatgcc
    13861 tactagaatt ctccttagaa aacgccgttt caagtgctat cactgttcaa aaatgatggt
    13921 cgctgaaact tctatcgtca agaagaatca ccaaatccct cgtatcatca accaaaaaat
    13981 tgcgcaaaag ttgattgaga agatttctat gaccgatatt gctcatcagc tggccatttc
    14041 aacttcaact gttattcgta agctcaatga ttttcacttt aaacatgatt tttcttgtct
    14101 tcctgagatt atgtcttggg atgagtatgc ttttacaaag ggaaagatga gcttcattgc
    14161 gcaagatttt aacaatctca atatcatcac tgttcttgag ggtagaacac aagctatcat
    14221 tcgaaatcac tttcttcact acgatagagc tgtccgatgt cgcgtcaaaa tcattactat
    14281 ggatatgttt agcccttact atgacttggc taaacagctt cgctttcaaa tttctaggct
    14341 caggctgaaa cagtctccca gactgtttca ctcccgaatg ctaaaatcgt tcttgatcgc
    14401 tttcacattg tacaacatct tagccgtgct atgagtcgtg tgcgtgttca aatcatgaat
    14461 cagtttcatc gaaaatccca tgaatacaag gctatcaagc gctactggaa actcattcaa
    14521 caggatagtc gtaaactcag cgataaacat ttttatcgcc ctacttttcg tatgcattta
    14581 accaataaag agattttaga caagcttttg agctattcac aagacttgaa aca
//
LOCUS       DAVLBE010000044        14102 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.044, whole genome shotgun sequence.
ACCESSION   DAVLBE010000044 DAVLBE010000000
VERSION     DAVLBE010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14102)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14102)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14102
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.044"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            207..443
                     /locus_tag="VXB91_001512"
     CDS             207..443
                     /locus_tag="VXB91_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecX"
                     /protein_id="HEV0470940.1"
                     /translation="MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVR
                     YGIGCHRDFIVYHYRVAYRLYLEKLVMNRGFISC"
     gene            674..1960
                     /locus_tag="VXB91_001513"
     CDS             674..1960
                     /locus_tag="VXB91_001513"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HEV0470941.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGVRNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            2161..2628
                     /locus_tag="VXB91_001514"
     CDS             2161..2628
                     /locus_tag="VXB91_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HEV0470942.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYDILTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK"
     gene            2661..2754
                     /gene="ffs"
                     /locus_tag="VXB91_001515"
     ncRNA           2661..2754
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="VXB91_001515"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(2837..3978)
                     /locus_tag="VXB91_001516"
                     /pseudo
     CDS             complement(2837..3978)
                     /locus_tag="VXB91_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518706.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            complement(4033..5103)
                     /locus_tag="VXB91_001517"
     CDS             complement(4033..5103)
                     /locus_tag="VXB91_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000401842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction enzyme HsdR N-terminal
                     domain-containing protein"
                     /protein_id="HEV0470943.1"
                     /translation="MEIDKVKADLKQVGKRVADLSQSITNEEQTKNAFIMPFFQALGY
                     DIFNPLEFVPEFTADVGIKKGEKVDYAIILDGEPQILIECKSITENLTKHDSQLFRYF
                     VTTKSKFGILTNGREYKFFTDLDEPNKMDTTPFLTIDVTDIKENQFTEIIKFHKENFD
                     IDNIVSSASELKYLNNLKAFLTENITTPSDSFLRYLTSEIYEGRVTQNILTTFSPIIV
                     KGFNQFITERVNEKLSAALNTSVETKVTTDIPKVEAEAEEIVEVTDEIITTPAELEVY
                     TVVKMLARDVVSPERVFYRDNRSYFNVLVDDNIKKWVLRYRSNSKKSTIEIRDKGIFP
                     VSTPLEVANYANEILEVIKKFS"
     gene            complement(5120..5500)
                     /locus_tag="VXB91_001518"
     CDS             complement(5120..5500)
                     /locus_tag="VXB91_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HEV0470944.1"
                     /translation="MTLAKLCEEYQVELCLFDGSNWHNSGFYNPDTNVLAIDHNLTPE
                     QQIQVALHELGHKDHTRSEHQNARLRCENEADRNMIHHLVKDALENLDDPTEFDYLKF
                     MSYYNLKTMTNEIMVKEEYLALVN"
     gene            complement(5513..5776)
                     /locus_tag="VXB91_001519"
     CDS             complement(5513..5776)
                     /locus_tag="VXB91_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEV0470945.1"
                     /translation="MYRLDIDKKALKQLKKLDTPTRKQILSWLAKNIENTTNPRQHGK
                     ALKANLAGYWRYRVENYRIICDIQDDKLVVLAVEIAHRRDVYK"
     gene            complement(5776..6009)
                     /locus_tag="VXB91_001520"
     CDS             complement(5776..6009)
                     /locus_tag="VXB91_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0470946.1"
                     /translation="MTITINFTEKNSYITDYLNKHGIDTTTMDFDDFMALMEDIEDAR
                     AADQAYMEYLADPATYTMDEVLDELGLTREDIA"
     gene            complement(6009..6377)
                     /locus_tag="VXB91_001521"
     CDS             complement(6009..6377)
                     /locus_tag="VXB91_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0470947.1"
                     /translation="MFETFEKIKELAKKRGKALGQVEEDLGYGRNTLYKIKNSTPNAE
                     RIAEIANYFNVSTDYLLGRTDNPAIAGSDEFAQVNGQIIDLRKAAANTMLFDGKPLNE
                     DDIDFITSVLSAHFKSKGER"
     gene            6949..7140
                     /locus_tag="VXB91_001522"
     CDS             6949..7140
                     /locus_tag="VXB91_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001112859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEV0470948.1"
                     /translation="MPDIANGRERVIAFLKEKGIKKATLAVAYGFKRQEVTNILSGTT
                     KGPRANSFILQVIEDYGIE"
     gene            7163..7366
                     /locus_tag="VXB91_001523"
     CDS             7163..7366
                     /locus_tag="VXB91_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001247546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0470949.1"
                     /translation="MRPKRYPYSGQKESTFVKADPELVEKLLRNTSFLECLQKKPINF
                     QIDSEEFKRLSYEAIHDTSQVTQ"
     gene            complement(7521..7688)
                     /locus_tag="VXB91_001524"
     CDS             complement(7521..7688)
                     /locus_tag="VXB91_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzC family protein"
                     /protein_id="HEV0470950.1"
                     /translation="MANTPIKPGTDNQKPGRYVEVGPRGGKVTNGHTATIGKGDRLPP
                     TSAKGNGWKKV"
     gene            7708..8073
                     /locus_tag="VXB91_001525"
                     /pseudo
     CDS             7708..8073
                     /locus_tag="VXB91_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
     gene            complement(8293..8472)
                     /locus_tag="VXB91_001526"
     CDS             complement(8293..8472)
                     /locus_tag="VXB91_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0470951.1"
                     /translation="MREVIQELLDSSMSTSAISQGAGVPWTTVSDLRKGKTSMDKMAL
                     LTAEKLYEFATTDKQ"
     gene            complement(8614..8763)
                     /locus_tag="VXB91_001527"
     CDS             complement(8614..8763)
                     /locus_tag="VXB91_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0470952.1"
                     /translation="MNKEDWLRLLEKAIDNIPETVTAIASLVTAITVARQNKKRKPKS
                     RQRKR"
     gene            9068..9511
                     /locus_tag="VXB91_001528"
     CDS             9068..9511
                     /locus_tag="VXB91_001528"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HEV0470953.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAADGVRTGGFGSTGH"
     gene            9513..10028
                     /locus_tag="VXB91_001529"
     CDS             9513..10028
                     /locus_tag="VXB91_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEV0470954.1"
                     /translation="MKIIFVRHGEPDYRELEERSYIGFGIDLAPLSEMGRQQVQKLSK
                     NPLLSSAEIIVSSAVTRALETASYVVCATGLPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENKGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            10042..11403
                     /gene="radA"
                     /locus_tag="VXB91_001530"
     CDS             10042..11403
                     /gene="radA"
                     /locus_tag="VXB91_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HEV0470955.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINEAAKLGFTKIYVPQNSLTGITLPKEIQVIGVTTIQEVLKK
                     VFA"
     gene            11476..11973
                     /locus_tag="VXB91_001531"
     CDS             11476..11973
                     /locus_tag="VXB91_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HEV0470956.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     TVVEL"
     gene            11998..12781
                     /locus_tag="VXB91_001532"
                     /pseudo
     CDS             11998..12781
                     /locus_tag="VXB91_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749763.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
     gene            12926..13894
                     /locus_tag="VXB91_001533"
     CDS             12926..13894
                     /locus_tag="VXB91_001533"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEV0470957.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVAVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
BASE COUNT         3933 a         2333 c         3137 g         4699 t
ORIGIN      
        1 ctaataggat ttacccaaaa gttttaaggc ggtcttttta gaactttaat tgtttgaaat
       61 ttaggtagca aatttgtttc tattttgtca acttttccta tttttatctt gttgaggctg
      121 gtattttaac aattcaggaa ttgatagtga atgtgtaaaa ttttttgtta gaataagttt
      181 ataaaaaaga aaaggagtat ttgattatgt tacaaaaaat ttatgagcag atggctaatt
      241 tctatgatag tattgaagaa gagtatggtc ctacatttgg tgataatttt gactgggaac
      301 atgttcattt taaattttta atttattatt tagtgagata tggcattggt tgtcataggg
      361 attttatcgt ttaccattat cgtgttgctt atcgtttgta tcttgaaaaa ttggtaatga
      421 atcggggttt tatttcttgt tgaggtaatt ttagtaaatt tccgaactaa tttactcttt
      481 tatgtaaaga taatagtaaa tagctagtaa tttttctaaa tcatttttta atagttggaa
      541 atagcaaatc tttctattgt ttcttcttga taaaaaggcg attttttatt ataataaatt
      601 gtaagatata attgcaggtg agagtcctgc catgtatgtg agaaaggaag agcctgaggg
      661 ctcagacaaa attatgactt cagttgttgt tgtaggtacc caatggggtg atgaaggtaa
      721 agggaagatt acagacttcc tttcagcgaa tgcagaagtg attgcacgtt accaaggtgg
      781 tgataatgct ggtcacacga ttgtgattga cggtaagaaa tttaagttgc acttgattcc
      841 atctgggatt ttcttccctg aaaaaatatc tgtcattggg aatggtatgg ttgtaaatcc
      901 taaatctctt gtaaaagagt tgagctatct tcatgaggaa ggtgtaacaa ctgataactt
      961 gcgtatttct gatcgtgcgc atgttatttt gccttatcat atcgagttgg atcgcttgca
     1021 agaagaagct aagggcgaca ataagattgg tacgacaatt aagggaattg gtccagctta
     1081 tatggacaag gctgctcgtg ttggaattcg tattgcagat cttttagata aagatatttt
     1141 ccgtgagcgt ttagaacgta accttgctga aaagaatcgt ctttttgaaa aattgtatga
     1201 cagtaaagcg attgttttcg atgatatttt tgaagaatat tacgaatatg gtcaacaaat
     1261 caagaaatac gtgatagata catctgttat cttgaatgat gcgcttgata atggcaaacg
     1321 tgtgcttttt gaaggtgcac aaggtgttat gctagatatc gaccaaggta cttatccatt
     1381 tgttacgtca tcaaaccctg tagctggtgg tgtgacaatt ggttctggtg tcggtccaag
     1441 caagattgac aaggttgtag gtgtatgtaa agcttatacg agtcgtgtag gagatggtcc
     1501 tttcccaact gagttgtttg atgaagtggg agaacgtatc cgtgaagtgg gtcatgagta
     1561 tggtacaaca actggtcgtc cacgtcgtgt aggttggttt gactcagttg tgatgcgtca
     1621 tagccgtcgt gtttctggta ttactaacct ttctttgaac tctattgatg ttttgagcgg
     1681 tttggatact gtgaaaatct gtgtggccta tgatcttgac ggtcaacgta ttgactacta
     1741 tccagctagt cttgagcaat tgaaacgttg caagcctatc tatgaagagt tgccaggttg
     1801 gtcagaagat attaccggag ttcgcaattt ggaagatctt cctgagaatg cgcgtaacta
     1861 tgttcgtcgt gtgagtgaat tggttggcgt tcgtatttct actttctcag taggtcctgg
     1921 tcgtgaacaa acaaatattt tagaaagtgt ttggtcctaa gagattttta agatttgttt
     1981 aagataggtc gggtatacta tagacagtta caagaagacc tcctaacttg ttgtaacaaa
     2041 tatcctaaac ttttcttttt cataataatc tccctataga gtcaccgcat tcggtggctt
     2101 cttttgtgtt gggattcatg atataataat aaaatcgata agtaggaaaa gagaaaagag
     2161 atgtattata cgcttgaaga aaaagaagtc tttatgaggg aggctttgag agaggctgag
     2221 attgctcttg aacacgatga aattccaatt ggttgtgtga ttgtcaaaga tggggaaatc
     2281 attggtcgtg ggcataatgc gcgtgaggaa ttacagcgag cggttatgca tgcggaaatt
     2341 atggctatag aggatgcgaa cttgagtgag gagagctggc gcttgctgga ttgcacactt
     2401 tttgtgacca ttgaaccttg tgtcatgtgt agtggggcga ttgggcttgc ccgcattcca
     2461 aatgtggtct atggggctaa aaaccagaaa tttggcgctg ctgggagttt gtacgatatc
     2521 ttgacagatg agcgtctcaa tcatcgtgtg gaggttgaaa taggaatttt ggaagatgaa
     2581 tgcgcagcta tcatgcagga tttttttaga aatagacgga aaaaataatt ttgcttttaa
     2641 aatgaatagg aatgtgatat aataaatagt ggagcaacag ttctgcgtga agcgggtcag
     2701 gggaggaatc cagcagccct aagcgatttg aattgtgtgc tcttttttcg tgcactttaa
     2761 aaacccttta aaatcaacac tttaaggggt ttttgtttgt cttgtataag aaaaaggggc
     2821 agacgagggg cacaatttaa aattttatct tgtctaactt gctagatatg tctgatacca
     2881 ttttttgagt aacgtgagaa taaatctcta gtgtggtctt tgagtcacta tgccctactc
     2941 tgtccatgat ggcagtcaag ggaatgccca gctcagcaag tagggatatg tgagaatgtc
     3001 taaatgtatg tgtagttatg tttttttcta tgccgatttt ttgaccatgt cttttcaatg
     3061 cacaaataac cctggcattt gttattggtt ctcctagagt attgatgaaa ataaaatctg
     3121 tatcaaatcc atttgtcgca ttctctatta tttgctcttt gataatatct aacacttttt
     3181 gaggtgctgt tataacccta tcggacttga ttgtctttgg tgtagttctc tctttttgtc
     3241 tgaaatcgta tgtatgcttg atgtgaatag tctttttaga aaaatctata tcttccttgt
     3301 agtttaaggc tgccagctct ccatacctca tgccagtaag aaaaagaact ttagctattc
     3361 ggatatactt tgtaattcga taatcacata gggcctcgtc ttttaaattt tggatgaata
     3421 acttaaactc tttttggtct aagtattttg tatttttctt tctgagttcg tcggatgtaa
     3481 ttacttttct aggcgtttca acaaatagca tttcatttgt atcaatataa ttcattctga
     3541 tagcaaattt cattatctga ttgagcttga atttgatttt agaaacatag ttatgagatc
     3601 tcccatcttg taatagttga tctattactt tttgtaataa acgtctatca aatttctaac
     3661 taggtagtcg ccctctatct gctttaaaat ctcttttttt acattctttg aagcgtagac
     3721 ggttgagttt tttacgccgt gtttccaatt ctcctcaaat tcttcatata gtttttcaaa
     3781 agttatatta gaaacagaat gttgtttttc tcctaacttt tgttttatct tttcctgaag
     3841 taaaatcgca gcttgatttc ttgcttgggg agtttttttc tccatcgtta ctgagacttt
     3901 ttttaatttc tcagtatatg gatctttgta tctctcaaaa aatttatatt tgccgtttgg
     3961 caattcttcc atccacattg attttacctc acttttttga taaaatgggt atagtaaaga
     4021 gggctttttt tattatgaga atttcttgat tacttctaaa atttcattgg cataatttgc
     4081 gacttcgaga ggggtagaca ccgggaagat gcctttatca cggatttcga tagtgctttt
     4141 ttttgaattt gaacgataac gtaataccca ttttttgatg ttatcgtcaa ccaaaacatt
     4201 gaaatagcta cggttatctc tgtaaaatac acgttctgga gaaactacat ccctagcaag
     4261 cattttaaca acagtataaa cttctaattc agcaggagtt gtgataattt cgtcagttac
     4321 ttcgacaatc tcttcagctt cagcttcaac ttttggaata tcggttgtta ctttggtttc
     4381 aacgcttgta ttaagtgcag cacttaattt ttcattaact cgctctgtga tgaattgatt
     4441 aaaccctttc acaataatgg gagaaaatgt cgttaagata ttttgagtaa cacgcccttc
     4501 atagatttca gaagttagat atctgaggaa gctatctgac ggtgtagtga tattttcagt
     4561 aaggaacgct ttaagattgt tgaggtattt caattcagaa gctgatgaaa caatattatc
     4621 aatatcaaaa ttctctttgt ggaatttgat gatttcagta aattgatttt ctttgatatc
     4681 agtcacatcg attgttaaga atggagttgt gtccatttta tttggctcat ctaaatcagt
     4741 aaagaattta tattctctac catttgtcaa gataccgaat tttgatttag tagttacgaa
     4801 atatctgaat agttgagagt cgtgcttagt aaggttttct gtaattgatt tacattcaat
     4861 taggatttga ggctcgccat ccaaaatgat cgcatagtcg actttttcgc cttttttaat
     4921 gcccacgtcg gcagtaaatt ccgggacaaa ttcaagtgga ttgaagatat catatccaag
     4981 cgcttggaag aacggcataa tgaaggcatt ctttgtttgt tcttcattcg taatgctttg
     5041 gctgaggtct gctacacgtt tgccgacttg ttttaaatcg gcttttactt tatcaatttc
     5101 catattgata ctcctttttt taatttacta atgctaaata ctcttcttta accatgattt
     5161 catttgtcat ggtttttaga ttgtagtaag acatgaattt gaggtaatca aactctgtgg
     5221 ggtcgtctaa gttttctaga gcgtctttta cgagatgatg gatcatattc ctatcagctt
     5281 cgttttcaca gcgtagacgg gcgttctggt gctctgagcg tgtgtggtct ttgtgtccaa
     5341 gttcgtgtag ggcgacttgg atttgttgtt caggagtcaa gttgtggtca atagcgagca
     5401 cgtttgtgtc tggattgtag aaaccgctat tgtgccagtt tgaaccgtcg aagagacaaa
     5461 gttctacttg atattcttcg cagagtttag cgagtgtcat agttctcctt cgttatttat
     5521 agacatctct gcggtgggcg atttccacgg ctaggacgac tagtttatcg tcttggatat
     5581 cacagatgat gcggtaattc tctactctgt atcgccagta acctgcaagg ttggctttta
     5641 gtgcttttcc gtgttgtcgt ggattggtcg tgttttcaat gtttttagca agccaggata
     5701 ggatttgttt tctggttggg gtatctagtt ttttaagttg cttgagagct tttttatcaa
     5761 tatctagccg atacattaag caatatcctc tcgagttagt cctagttcat ccaagacctc
     5821 atccatggta taagtagctg ggtcggctaa atactccata taggcttggt cggctgctcg
     5881 tgcgtcttcg atatcttcca tgagtgccat gaagtcgtca aaatccatgg tcgttgtgtc
     5941 gataccgtgt ttgtttaggt agtccgtaat gtaggaattt ttttctgtga agttgatagt
     6001 gatagtcatt agcgttctcc tttgcttttg aagtgggcgg ataggacgga tgtaatgaag
     6061 tcgatatcat cttcatttag tggtttcccg tcaaataaca tggtgttggc tgctgctttg
     6121 cgtaagtcta tgatttgtcc gtttacttgg gcaaattcat cactcccagc gatagcaggg
     6181 ttatctgttc gtccgagcag gtagtcggtg gatacgttga aataattagc aatttctgcg
     6241 atacgttcag cgtttggcgt agaatttttt atcttataga gtgtatttct accataacct
     6301 aagtcttctt ctacttgtcc aagagctttt ccacgctttt ttgccaattc ttttattttt
     6361 tcaaatgtct caaacattgt taaatcaacc tttctaagac atcacaaaaa aaatttaaca
     6421 aatttggtgt aaaaaggttg actaattatc ccaaaaggtg taaaatgttt tttgtaagtg
     6481 ataaacaact aaaaaaacaa ctaagaaata aattataaaa atgttttggc gaacggtatt
     6541 tatagattta ttggtgtttt tattatgctt taattttagc cgatttggtg taagttgtca
     6601 agtataatgc agaaaaatag ttacattttt agttgtttct tatttacaaa taagtaaaga
     6661 ggaggaacgt gctgatggta agtattctta aaaatttaga acaagaaaaa gaccaccttg
     6721 aaaaagtcat taaggtagtc agcgctggtg gtaaatttct gagattgcca tatcaaaaaa
     6781 gtcacgctcg attagtgaga atctgaaatt gatttctcaa aatctttacc atcatcgtag
     6841 atgtcgcgtt tgcttgcttt gagtaaatat tctttaaaag tcataaggtt aactcctttc
     6901 tgcttatatt atagcagaaa aagaagaaag aaaaagaaag gagaaaatat gccagatatc
     6961 gcaaacggtc gcgaaagagt tattgctttc ttgaaagaga aaggcattaa aaaagcaact
     7021 ctagcggttg cttacggctt taaacgacag gaagtgacaa acattctaag tggaacgact
     7081 aaaggtccac gagcgaacag tttcattctt caggttattg aagattatgg gattgagtag
     7141 gaaagatttg aggagtagga aaatgagacc aaaacgatat ccgtatagtg gacaaaaaga
     7201 gtccaccttt gtaaaggcag accctgagtt agttgaaaaa cttttaagaa acactagttt
     7261 tcttgagtgt ttacaaaaaa agcctatcaa ttttcagata gactcagaag aatttaagcg
     7321 tcttagctat gaagccattc atgatacttc tcaagtaact caataggagg aaggaataaa
     7381 atgattcacc attatataac tcactatgcc agcaatggga aagattacgc cgaagcatgg
     7441 attcaaattg attttttggg aatgtgcttt tgtgtatgga aaaagcgtac aaccattgaa
     7501 cgattgtacg caaacgaaga ttagactttt ttccaaccgt tgcctttagc agatgtcgga
     7561 gggagccgat caccttttcc gatagttgcg gtatgaccat tagtaacttt tccgccacga
     7621 ggtcctacct ctacatagcg accaggtttc tgattatctg ttccaggttt tattggagta
     7681 tttgccatac tatctcctcc tttctataag tttgagaaaa tcaacggtat ctggtattat
     7741 ttcgatggct caggctatat gctttcagac cgctggaaga agcacacaga cggtaattgg
     7801 tactactttg accaatcagg cgaaatggcc acaggctgga agaaaatcgc tgacaagtgg
     7861 tactattttg atgtagaagg tgccatgaag acaggctggg tcaagtacaa ggacacttgg
     7921 tactacttag acgctaaaga aggcgccatg gtatcaaatg cctttatcca gtcagcggac
     7981 ggaacaggct ggtactacct caaaccagac ggaacactgg cagacaagcc agagttcaca
     8041 gtagagccag atggcttgat tacagttaaa taaatagaaa ggaaactttc taaattgttc
     8101 tttcaccgca ggctcaggct tgcggttttt tatttgctct gattcttcaa aaaagcgttt
     8161 tcttgaagaa tagggaggag gaatggcagg gtattattgc caaaaacgcc attttgttaa
     8221 taatagctcc tttttatttt ttgattattg tcaaaaacgg tgttttgtca aaaataaaaa
     8281 cagtgaccga aatcactgct tatcagttgt agcaaattca taaagttttt ctgctgtgag
     8341 aagtgccatt ttgtccatgc ttgtttttcc ttttctgagg tcagaaacag tagtccatgg
     8401 aactccagca ccttgggaaa tagcagatgt agacatcgaa ctgtctaaca attcttgaat
     8461 aacttctctc atcttatttg tcctttttat tttttagata aatatataca ttgaccgcaa
     8521 ttataaaaat agctattgca ctaaccattg cttttcctct tttcatttga taaaatagag
     8581 gtgtgagggg ctttcgcccc aacctcttag cgttcacctt tttctttgac gggatttcgg
     8641 tttacgcttt ttgttttgcc ttgcgaccgt tattgcagtc accagacttg ctatagcagt
     8701 taccgtttca gggatattat ctatcgcctt ttccagtaac ctaagccaat cttctttgtt
     8761 caacttcctc acctcctttc cttatcttga ttatattata tcacggtaaa ccgtgaaagt
     8821 caagcgattt gatgaagttt ttttgaaaaa caaaggggca aaaaaggggc aaaagtgtcg
     8881 taaacctctg taaaacgatg taaaaaatca actttgccct cgctttaaag ctctaaattt
     8941 caacgtattg tgaaacagtg taaattatcg tatcgcctat aattgttgtg tgctcttttt
     9001 ttcgtgcttt ttccgaataa ataagataga ataatctaga ataaatgata atagaaaaga
     9061 gaaaattatg aaaattcgtg gttttgaatt ggtttcgagt tttacagatg aaaatttatt
     9121 gcccaagcgt gagacagcgc atgcggctgg ttacgactta aaggttgctg tgcgtacagt
     9181 tgttgcgcca ggagagattg tcttggttcc gacaggggtt aaggcttata tgcagccgac
     9241 tgaggttctc tacctctatg atcgttcttc aaatcctcgt aagaagggct tggttttaat
     9301 taactcagtt ggggtcattg atggggatta ttatggaaat cctggaaatg aagggcatat
     9361 ttttgcgcag atgaagaata tcacagatca agaggttgtt cttgaagttg gggaacgtat
     9421 tgtccaggct gtttttgcta ctttcttaat tgcagatgga gatgcagctg atggcgttcg
     9481 aactggtgga tttggatcga cagggcacta gaatgaagat tatctttgta cgtcatgggg
     9541 agccagatta ccgtgagtta gaggagcgtt cttatatagg atttgggata gatttggcac
     9601 ccttgtctga gatgggacgg cagcaagtcc agaaattgag caaaaatcct ttactctcgt
     9661 cagctgaaat aatcgtatct tctgcagtca caagagcttt agaaacggct tcgtatgtgg
     9721 tctgtgctac gggtcttcct ttaagagtag agcctttatt acatgaatgg caggtctata
     9781 aaacaggaat agaaaacttt gaaacagcta gaagactgtt tttagaaaac aagggggagt
     9841 tgcttcctaa tagtcctatt caatatgaga cagctacgga aatgaagtct cggtttctag
     9901 aatgtatgtc taagtatcga gaacatcaga ctgtggtagt tgttgctcat cgaatgctca
     9961 tgcgccagtt tgtgccaaat gagaagattg atttttgcca agtgattgag tgtgagttag
    10021 agatatagaa agaggtttgt catcgcaaag aaaaaagcga catttgtatg tcaaaattgt
    10081 gggtataatt cccctaaata tctgggacgt tgccccaact gtgggtcttg gtcttctttt
    10141 gtggaagagg ttgaggttgc cgaggtcaag aatgcgcgtg tgtccttgac aggtgagaaa
    10201 accaagccca tgaaactagc tgaggtgact tccatcaatg tcaatcgaac caagacggag
    10261 atggaggaat tcaaccgtgt gcttggaggc ggagtggtac caggaagtct cgtcctcatc
    10321 ggtggggatc ctgggattgg gaaatcaact cttctcctac aagtctcaac ccagttgtcc
    10381 caagtgggga cagttctcta tgtcagtggg gaggagtctg cccagcagat taaactacgt
    10441 gcagagcgct taggtgatat tgatagtgag ttttatctct atgcagagac caatatgcag
    10501 agtgttcgtg cagaagtgga gcgtatccag ccagactttc tcattattga ttccatccag
    10561 accatcatgt ctcctgagat ttcaggggtg caggggtctg tttctcaggt acgtgaagtg
    10621 accgctgaac tcatgcagtt ggccaagacc aataacattg ccatctttat cgtaggtcat
    10681 gtgaccaaag aaggaacctt ggctgggcct cgtatgttgg agcatatggt ggatacggtg
    10741 ctttactttg aaggggagcg tcaccacacc tttcgtattt tgagagcggt caaaaatcgt
    10801 tttggttcca ctaatgagat tgggattttt gagatgcagt cgggcggctt ggttgaggta
    10861 ctcaatccga gtcaagtttt cctagaagag cgtttggatg gggcgactgg ttcctccatc
    10921 gttgtaacca tggaagggac gcgtccgatt ttggcggagg ttcaggcttt ggtaacaccg
    10981 accatgtttg gaaatgccaa gcgtactacg acaggacttg attttaaccg tgctagcttg
    11041 attatggctg ttttggaaaa acgggcaggg cttctcttgc aaaatcagga tgcctatctc
    11101 aaatctgctg gtggtgttaa attggatgaa cctgccattg acttggctgt tgcagttgct
    11161 attgcttcga gctacaaaga caagccaact aatcctcagg aatgttttgt cggagaactg
    11221 ggcttgacag gagagattcg gcgcgtgaat cgtattgagc aacgcatcaa cgaagctgct
    11281 aaactgggct ttactaagat ttatgtacct cagaattcct tgacaggaat cactctgcct
    11341 aaggaaattc aggtcattgg cgtgacaacg attcaggaag tcttgaaaaa ggtctttgca
    11401 taatccgtga caaattctct taaaaatgat aagataggag aaatatttga ctatcaaatt
    11461 ttcaaggagg gaatcgtgtc gtattttgaa cagtttatgc aagccaatca ggcttatgtt
    11521 gccctacatg ggcagttaaa tctgccactt aaacctaaaa ccagagtagc cattgtgacc
    11581 tgtatggact cacgtttgca cgttgcgcaa gctctgggct tggcacttgg ggatgctcat
    11641 atcttgcgga atgcaggtgg tcgagtgact gaagacatga ttcgttcgct agttatttcc
    11701 cagcaacaaa tggggacaag agagattgtg gtattgcacc atacagactg tggtgctcag
    11761 acctttgaaa atgaaccttt tcaggagtat ttaaaagagg aattaggtgt agatgtgtca
    11821 gaccaggact tcttgccctt ccaagatata gaagagagtg tacgcgagga tatgcaactg
    11881 cttatcgagt ctcccctaat accagacgat gtcattatct ctggtgctat ttacaatgtt
    11941 gatacaggaa gtatgacagt cgtagaatta taaatacttc atttagaaag aaagtgtatg
    12001 aagaaaagca gtattttatt tatttttatt ttattgctat gtattggttt acagtatgaa
    12061 accatctact atacggacgg ttcgaggtca ggtgcggaat atggactaat gggagtttct
    12121 atctttctag ctctctttta catgattccg gctctttatt ttctcttccg tattgggaaa
    12181 aaatgggaat tgccaaagaa ggttttgatt ctgtctttat tgggagggat gttcctttca
    12241 ggctggttgt ctagttttgc taatacttat atacatgatt tactgggggt tcttttccca
    12301 gatagtccat ttttaaatgc ctttgaaagt gctattgtgg ctcctttggt agaagaaccc
    12361 ttgaaattat tgccacttgt ttttgttttg gctttgattc ctgtgcgaaa attaaaattt
    12421 ttgtttttac ttggaattgc ctccggtttg ggattccaaa tgattgagga tattggttat
    12481 attcgtacgg atttgccaga gggctttgac tttactattt cgcgaatttt agagcgtatc
    12541 atctcaggaa ttgcctctca ctggactttt tcaggtctag ctgtagtagg tgtttacttg
    12601 ctttacagag cctataaagg acagaaggtt ggcaagaaac agggtcttat tgtttaactc
    12661 tccttttgtg gagttggaaa cagagttgcc tttagcgatt ccagtggtta cggctattgc
    12721 tctctatggt tattatcatg cttattgctt tgttgagaaa cacaatgagt tgatgaccta
    12781 gaatattttt caaaagaatg atgcaagggt acaaatatgg tgcccttctt ttatttttga
    12841 ttgaaaaata gtgcaaaaag cgctacaatg gtagatggaa aatcttgtga aaagcacaag
    12901 cgatacatat ataccggagg aaatcatgtc tttttctgat ttaaagctgt ttgccctttc
    12961 ttctaataaa gaattggcag aacgtgtggc gcaggagatt gggatagagt tggggaaatc
    13021 aagtgttcgc caattttcag atggagagat tcaggtcaac attgaagaat caatccgtgg
    13081 gaaacacgtc tttatcttac aatcaactag ttcgcctgta aatgacaatc tgcttgaaat
    13141 tttgattatg gtagatgctt tgaagcgtgc gagtgcagag tctgtcaatg ttgtcatgcc
    13201 ttactatggg tatgcacgtc aggatagaaa ggcgagagcg cgtgagccaa tcacttcaaa
    13261 acttgtcgca aatatgcttg aagtagctgg agtggatcgt ttattgacca tcgacttgca
    13321 tgctgcgcaa attcaaggat tctttgatat tcctgtggat catttgatgg gtgctcctct
    13381 aattgcagat tattttgagc ggcgtggtat ggttggttct gactatgtgg ttgtcagccc
    13441 ggaccatgga ggggtgactc gtgctcgtaa gttggcagaa tttttgaaaa catctatcgc
    13501 tattattgat aaacgtcgta gcgttgataa gatgaatact agtgaagtta tgaacatcat
    13561 cggtaaggtt gaaggcaaga cttgtatctt gattgatgat atgattgata ccgctggaac
    13621 gatttgtcat gcggcagatg ctcttgcgga agctggtgct gttgcagtct atgcaagctg
    13681 tacgcaccca gttctttctg gtcctgctac ggacaatatc caaaaatcag ctattaagaa
    13741 attggttgtt ttggatacca tctatctgcc agaagagcgt ttgattgata agattgagca
    13801 gatttcaatc gctcatctcc taggggatgc tatcgtacgt attcatgaaa aacgaccact
    13861 ttctccactt ttcgatattg agaaaaaaat ttaatgacca agcctgagat gattctcagg
    13921 ttttttcgtc ttttttccga ataaatggat agtagcggtg aatctagtaa agctagattt
    13981 aaaactgtga tataataaaa agagaagaaa tatgactata cgtcatcaga agtttcagcg
    14041 accatcattt ttgaacagtg atagcacttg aatcgacgct ttctaaggag aattctagta
    14101 gg
//
LOCUS       DAVLBE010000045        13828 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.045, whole genome shotgun sequence.
ACCESSION   DAVLBE010000045 DAVLBE010000000
VERSION     DAVLBE010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13828)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13828)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13828
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.045"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(174..1589)
                     /locus_tag="VXB91_001534"
     CDS             complement(174..1589)
                     /locus_tag="VXB91_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEV0470958.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLIGIDFYHKYKEDISLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWIDRRMIHFYEKFARTVLERYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEN
                     DINIEFAAEDAELLKNYTVDFLSFSYYMSVTQSALPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDEFNNLTVQDDYRIQYM
                     KEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGNGTFNRY
                     KKMSFTWYKGVIESNGESLFK"
     gene            complement(1602..3440)
                     /locus_tag="VXB91_001535"
     CDS             complement(1602..3440)
                     /locus_tag="VXB91_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEV0470959.1"
                     /translation="MSYKDTVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPGVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGVPVTPASYGSSVVPILIMV
                     WLMKYIEKMIAKLTPAVTKSFLQPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMY
                     GVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVKAGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDEGVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     DLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            complement(3458..4297)
                     /locus_tag="VXB91_001536"
     CDS             complement(3458..4297)
                     /locus_tag="VXB91_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEV0470960.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKTGDKVNPIDI
                     EKSFFLKNRDNMTRFTEMFINVPLELVYITEKIINLGKITLGNNFDEIIYINLTDHIS
                     SSIERYKEGIIISNPLRWEISKYYKEEFELGKRALQIIKKELGIELPIDEAAFIALHF
                     VNANLENNFQESYKITEIIMGIEKIIQDFYCTEFNQDSIDYYRFITHIKLFAHRLVEN
                     TTYCDDDDEDLLALMKNKYPREYECGEQVAMFIQTEYNYLLTSSELVYLMAHIRRLTK
                     NLD"
     gene            complement(4597..7155)
                     /locus_tag="VXB91_001537"
     CDS             complement(4597..7155)
                     /locus_tag="VXB91_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEV0470961.1"
                     /translation="MERSQFEEMFQLQSSRLTTQEKLQLFTSVFAGRYDVYAKNFINE
                     QGKIQYFPSYDYGWKQLPPEKRSFQTLTNSVLKSHFRGEAAIGIFPMHLDDSCYFLVL
                     DLDEGDWKEAGLTIRRIARERQMEAHLEISRSGYGLHIWFFFEEAILSRKARLFGKKL
                     LELAMQESMQLSFDSFDRMFPNQDVLPKGGFDNLISLPFQGEAYHQGRTVFVDEQFQP
                     YEDQWRYLQEIQKISTAKVALLIQEELGKQELDKELKIVLSNMIQLEKSSVTPKTLFF
                     LKNMASFSNPEFYLKQAMRQPTYQIPERMYLFGESDHYLWLPRGLLYPLQDKFKQVSV
                     EDRRKVQRSISVEFKGELTFEQELALSDMTSKENGLLHAETGFGKTVLGAALISERKT
                     KTIILVHNKQLLDQWLDRLNCFLTFEEEEAIRYTASGREKVIGYVGQYGGTKKWLSKL
                     VDVVMIQSLFKLENSQSLLDEYEMMIVDECHHVSALMFEKVVAQFRGKYLYGLTATPE
                     RKNGHEPIVFQRIGEILHTADKRETDFKRQLQLRFTSFGHLEIEKTKASNFIQLSDWI
                     ATDSARNQLILKDILAQVAEGRNILVLVNRIQQIDVFEKLLKEKEVDGCYIISGKTKV
                     RERTSLLETLEQLDKGFVLLSTGKYIGEGFDLPQLDTLILAAPFSWKNNLIQYAGRIH
                     RNYKDKSLVRIFDYVDIHVPYLEKMFQKRQVAYRKMDYRVIEGEEKQFVYVDSRYEKV
                     LREDLAGERQECLLILPYVHQTKLMNFLKEFRISQIEICIPETVANKAWLDQLKSQKI
                     KVSFTQSKIVTPILLVNKTIVWYGAMPLLGKVDEMTILRLESASIVSELVAGLR"
     gene            7703..8903
                     /locus_tag="VXB91_001538"
                     /pseudo
     CDS             7703..8903
                     /locus_tag="VXB91_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436304.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(9018..9821)
                     /locus_tag="VXB91_001539"
     CDS             complement(9018..9821)
                     /locus_tag="VXB91_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic/DOC family protein"
                     /protein_id="HEV0470962.1"
                     /translation="MQPTYNIDNPNLSYEAKRDLWRIGFGLQKVDNLVPSAYMESLAE
                     KQSRGELTYEQVYEDATAYHHTIDASTEEADLVSLRIVELLSRRGFSFSPATLLAIHK
                     ELFQDIFEPSIPVGQFRQTNITKNEPVLNGESVVYSDYSMIQMTLDYDFNQEKQVAYA
                     TLTQADVVKQIQHFISGIWQIHPFREGNTRTVTVFLIQYLREFGFDIDNIPFQQHSKY
                     FRDALVLDNAKILQRRPEFLTAFFENLLLGGQNDLSSEKMYLDLDLDFS"
     gene            complement(10102..10857)
                     /locus_tag="VXB91_001540"
     CDS             complement(10102..10857)
                     /locus_tag="VXB91_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3883 domain-containing protein"
                     /protein_id="HEV0470963.1"
                     /translation="MSKHPHYELLNLIGYGLAKFDKLFIKEFQCFSKSEFYRYVVSLG
                     IAETTGVVKNRMDLFDPYFDNNRKGWWQKAEVYRFRKDLIDMMFGNEDVHSYAEIVKM
                     LLASEGKKTGITIVEKPIVRTKFKRLQETGMEAENYFILHFDKEEKFQGGQLTDARLY
                     GDGYDFQVDVQEYSYLAEVKGIRKSKGRVRLTAKEFEKVKEFQSDFILSLVTNLDDIP
                     KLVLIDNPLKHFEFKKNIIKNEIIEYRSVEDLY"
     gene            complement(10927..13578)
                     /locus_tag="VXB91_001541"
     CDS             complement(10927..13578)
                     /locus_tag="VXB91_001541"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HEV0470964.1"
                     /translation="MSKELSSKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ITRYDLGRESFLTKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPEFGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNELAFEFSGMDRFEARKAVVAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTEDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNADGEMYVGEEAPEGDGWTQDEDVLDTWFSS
                     ALWPFSTMGWPEVDSEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVL
                     IHGLIRDEQGRKMSKSLGNGIDPMDVIEKYGADALRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNGGLTLDVAHDNVTKVATGEAGNVTDRWILHNLNETIAKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEEEKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQISEGSIVTAAYPTVNLAFEDLAAHTGVESLKDLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIFLPLADLLNVEEELARLDKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     EKDKQADYQAKYDVTVARIDEMKKLVK"
     gene            complement(13590..>13828)
                     /locus_tag="VXB91_001542"
     CDS             complement(13590..>13828)
                     /locus_tag="VXB91_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ribosome-binding factor A"
                     /protein_id="HEV0470965.1"
                     /translation="YNKLFLKLNHNTLVDIKSKLESLKLKHSRYYISKISKYDLKYNP
                     GNYTMSPLAAFAEIEEIYIELSKIGLVKIVNKSN"
BASE COUNT         4368 a         2913 c         2197 g         4350 t
ORIGIN      
        1 accaatctat cctaagttaa ctatttataa tcggctctct gtaacaaaat taaattaatt
       61 aatcccccta taaaataaag aggtttagaa tttgatgtct tccaaacctc tttatttcat
      121 atttaatgag atgctgcctt aaccgtgata atatctaatc atcaataaac aaactatttg
      181 aataaggatt ctccatttga ttcaatcact cctttatacc aagtaaagga cattttctta
      241 tatcgattga atgtgccatt tccatcatca tttcgatcaa cataaatgag accgtacctc
      301 ttagaaagct gtgcagtgga catagaaacg cagtcaatac atccccaaga cgtatagccc
      361 ataatttcca caccatcttg tagagcttca gctacttgca ataaatgttc tttcatatac
      421 tgaattctat aatcatcttg gactgttaag ttattaaatt catcttttat tagttgatct
      481 ttagcaccta atccgttttc cactataaat aatggaattt gataacggtc ataatatcta
      541 tttaaaatta tacgtagtcc aattggatca atttgccatc cccactcaga agactctaaa
      601 taaggattta ctaaaccacc aataatattc ccttctcctg aattatactg tgttggaaga
      661 gcagattgag tcacactcat gtaatagcta aaggataaaa aatctacagt ataatttttt
      721 aataactctg catcttcagc tgcaaactct atgttaatgt cattttcctt aaaatatctt
      781 tttgcataat tcggataata acctctaaca tgcacatctg aaaatagata atttagattc
      841 tcatactcat gagtcgccca tacatctttt ggatttggag tcattggata agctggcata
      901 gctaatacca tacaccccac cttaaactct gaattaatct cacgagcaat ttttgtaacc
      961 aaactcgagg cgactaattc atgatgtata gcttgatata attcttgttt cgaaagattc
     1021 tccttaggta tatctattcc tccactagta aacggtaatt ccaaaacaga gtttacttcg
     1081 ttaaatgtaa gccaatattt aactttatct ttataccttt ctaaaactgt tcgagcaaat
     1141 ttttcataaa aatgaatcat tctcctatca atccatccat gatattttct tgctaaatat
     1201 aatggagtct catagtgtga aagagttaca agtggttcta tcccgtgagc atgtagttca
     1261 tcaaacaatt catcataata tttcaaccca gcttcgttag gttcttcctc atctcctttt
     1321 ggaaaaattc tactccatgc aatagaagta cgaaaaacat taaagcccat ttcagaaaac
     1381 aaggatatat cttccttata tttatgataa aaatcaatac ctatcaattt taagttatct
     1441 tctgtaggat tttctgttgc ttctcctaat ccacctttgg gtaacacatc ctgaactgat
     1501 aagcccttac catcttcatt atatgctccc tctacttgat tagctgcaac agctccaccc
     1561 caaagaaaat catctggaaa aatggtcata actttcctcc attataatat taccagtaat
     1621 tccttagaat gctcgattgt ctgattatta ggtaatacta atacatctag aaaatcattg
     1681 gtattcgtta caattactgg tgtaactgtt tcgtagcctt tagtcttgat taaattcaag
     1741 tccatttcaa aaatcaactg atttttgaaa actctgtctc cttcttctac atgactaata
     1801 aaaccttgac cttttagctc aacagtatct aatccaatat gaattagtaa ctcaacaccc
     1861 tcatcactct tcaatccaat tgcgtgctta gtcggaaaaa tatttgtaat tttcccatca
     1921 aatggtgcat aaaccttacc ttcacttgga ataatcgcta ctccgtctcc aattagttta
     1981 tctgaaaatg ttttatcctg gacatcgctt aacggaatga tttctcctga tataggagaa
     2041 aatatcattt ttttatttga aactccagct ttaacttcta aattgctaga actctcttct
     2101 tcatcgattc caaatatata agctaataca aaggtaataa caaccgaaat aaccgccaca
     2161 attaaagcat ttacaatatt tgatggcaca tcagaataaa taaattgagg caacgctatc
     2221 aaagatggga cagcaaatag atacgcttta acactagtaa gacctgcaaa taatcccgct
     2281 aatccaccac caatcatagc tgcataaagc ggttttttat attttaaagt cacaccatat
     2341 aatgcaggtt cggtaatccc tgcaagtaag gctgagaaac ctgctgcaaa agcaatttgt
     2401 tttgtattat tatttttact ctttaatgca acagccatcg aagcagcccc ttgagctaag
     2461 tttgacccta acattgctgg aagaattaat acgtctggag tagcaataga tgccgccaaa
     2521 aaaataggtg caaaagccca atgcattcca gtcataacaa taaatggcat aatagcacca
     2581 agaatagcta atgtaagcca tccagctaca ccatacattt gcccaactag atttgataat
     2641 ccttcaccaa caattactcc aataggcccg actacaacta aggcaataca gcttgatact
     2701 aataatacta gcgtaggttg caaaaaactc ttagtaacag ctggtgttaa tttagcaatc
     2761 attttttcaa tatatttcat caaccaaacc ataataagaa ttggaacgac tgacgaacca
     2821 taactagctg gtgtcacagg tacaccaaat aaactaagag gattccctga ttgcaccatt
     2881 tgaacaaaat ttggatggag aagtacacct gctacagaca tagctaatgt agatgttact
     2941 tttaattttt gtgatgcaga ataagctaat aacagcggta agaaataata tggagcatcc
     3001 ccaaaaaatg tcaaaaaagc aatagtctga gaatctgatt gcaatatacc aagcattggt
     3061 aaaataatta ccaagacttt cagcatacct ccccctaaca ttgctggaat gattggagtc
     3121 atggaaccag cgatatactc aatgattctt tctaaaatat tccctttgtg cccttgaaca
     3181 actgaatcgg attcaaaatt gccaagttta acgaattctt tataataatt agctacatca
     3241 ttaccaagta taatttgata ttgtccattc tttttcataa tacctattac acctggtatc
     3301 ttcttcacat catcatcatt gactaaattt tcatctttta attctaatct taaacgtgtt
     3361 acacaatggg taactctatt gacatttttt tcacctccaa ttacatcgag gattttttgt
     3421 accgtatctt tataactcat ggtattctcc tattctatta atctaaattt tttgttaagc
     3481 gacgaatatg agccatcaaa taaactaatt cactagaagt cagcaaataa ttgtactccg
     3541 tttgtataaa cattgccacc tgttcaccac attcatattc tctaggatat ttatttttca
     3601 ttaatgctaa caagtcttca tcatcatcgt cacaataagt tgtattttca accaagcgat
     3661 gggcaaataa ttttatatga gttatgaatc tataataatc aatagaatct tggttaaact
     3721 cagtacaata gaaatcttga atgattttct caattcccat aattatttca gtgattttat
     3781 acgactcttg aaaattattt tctaaattag cattaacaaa atgtagcgct atgaatgcag
     3841 cttcgtcaat tggaagttca atacctaact ctttttttat tatttgtaaa gcccttttcc
     3901 caagttcaaa ttcttcttta taatatttcg atatttccca gcgtagggga ttcgaaataa
     3961 taatcccttc tttataacgt tctatgctcg aagaaatatg atccgttaaa ttaatataga
     4021 taatttcatc aaaattatta cccaatgtta ttttacctag gttaattatt ttttcggtga
     4081 tgtacaccaa ctccaaagga acgttaataa acatctctgt aaaacgggtc atattatctc
     4141 tatttttgag aaaaaaactt ttctcaatat caattggatt tactttatct ccagtttttc
     4201 ttccaaaagc tattcccctt ccaaaaagaa gaatatcgat atctttttta ctttgcgcaa
     4261 ttacggcatt gtggtttagt attcgtttta tgatcataaa atttcccttt taaaataaaa
     4321 ggaacctact taaaaacatc aagaaacttc ttctgatgtg attaaatagg ttcctgctca
     4381 cttgtattag tgataacatc cttttatttc aatttttaat ggtgacatga agcttaaata
     4441 attaataact ctgtaaccgt ttttatttta tgatatttca atctatttgt caagtactta
     4501 taaaaatttt tttattttgt gtgattcgaa tgtgataatg gcaacagtct cactaaagaa
     4561 atgaaaatca tacatagaaa tttttaaaaa ttttctctat cgtaaacctg ccactagttc
     4621 agaaactata ctagctgatt ccaaacgtaa tatggtcatc tcatctacct tccctaataa
     4681 tggcattgca ccataccaaa caatagtctt attcaccaaa agaataggcg ttactatttt
     4741 tgattgagta aaagacactt taattttctg gctcttcaac tggtctagcc atgctttatt
     4801 tgcaaccgtc tctggtatac atatctcaat ttgactaatc ctaaattctt ttagaaaatt
     4861 catcagtttt gtctggtgca cataaggtaa aataagcaga cattcctgtc tttcccctgc
     4921 taagtcctct ctcaacacct tctcatatct actatcaaca taaacgaatt gtttctcctc
     4981 accctcgatg acacgataat ccatctttcg ataagctact tgtcgtttct gaaacatctt
     5041 ttctaaataa ggaacatgaa tatccacata atcgaaaata cgcaccaaag acttatcctt
     5101 gtagtttcta tgaatccgac ctgcatactg aattaaatta tttttccaag aaaagggtgc
     5161 tgccaagata agcgtgtcca actgaggtaa gtcaaaacct tcgccaatgt attttccagt
     5221 agacaacaaa acaaaccctt tatctaactg ttctaacgtc tccagtaaac tcgttctttc
     5281 tcggactttg gtttttccgc taataatgta acagccatca acctctttct ctttcaataa
     5341 cttttcaaag acatctatct gttgaattcg attaactaaa accaagatat tccgtccttc
     5401 tgccacttgg gctagaatat ccttgagaat caactgattc ctcgctgagt ctgtagcaat
     5461 ccaatcactg agctgtataa aattacttgc tttggtcttt tcaatctcca aatgaccaaa
     5521 agaagtgaat cttaattgca attgccgttt aaaatccgtt tccctcttat cagcagtatg
     5581 gagtatctca ccaattctct gaaaaacaat aggctcatga ccattcttac gctcaggcgt
     5641 agccgtcaaa ccgtaaagat acttccctct aaactgagca acaacttttt caaacatcaa
     5701 ggcagagaca tgatgacact catccacaat catcatctca tactcatcca aaagactttg
     5761 actattttcc aacttaaata gagattgaat cataacgaca tcaaccagtt tactcagcca
     5821 tttcttagtc ccaccgtact gtccaacata gccgattacc ttttcacgac ctgatgccgt
     5881 ataacggata gcctcctcct cttcgaaagt caaaaagcag tttaagcgat ctagccattg
     5941 gtctaagagt tgcttattat ggactagaat aattgttttt gttttccgtt cagagataag
     6001 agcagcacct aaaacggtct tcccaaaacc agtctccgca tgaagtaaac cattttcttt
     6061 agaagtcata tctgacaggg ctaactcttg ctcaaaagtg agttctccct taaattccac
     6121 gctaatagac ctttgtacct ttctcctatc ttccacagat acctgcttaa atttatcttg
     6181 caatggatac agcaaacctc ttggcaacca taaataatga tcggattctc caaataaata
     6241 cattctctca ggaatttgat aggttggctg tcgcatagcc tgctttaaat aaaattcggg
     6301 attagaaaat gaagccatat ttttcaagaa aaacagtgtc ttgggtgtca cagacgattt
     6361 ttcaagttgg atcatattgg ataagacgat cttcaactcc ttgtccaatt cttgcttgcc
     6421 taactcctct tggattaaca gtgccacttt agcagttgaa atcttctgaa tttcttgtag
     6481 atacctccat tgatcttcat aaggctgaaa ctgttcatcc acaaagaccg ttcgcccttg
     6541 atgataagct tctccttgaa aaggaaggga aattaaatta tcaaatccac ctttaggaag
     6601 aacatcctga tttggaaaca tgcgatcaaa agaatcaaag gacagttgca tactttcctg
     6661 catagccaat tctaatagtt tctttccaaa caggcgagcc tttcgactca gaatcgcttc
     6721 ctcaaagaag aaccaaatat ggagtccgta acccgaacga gaaatctcta aatgggcttc
     6781 catctggcgt tccctggcta ttcttcgaat ggttaaacca gcttctttcc aatctccttc
     6841 atccaaatcc agtaccaaaa aataacagct atcatctaag tgcataggaa agataccgat
     6901 agctgcctcc ccacgaaaat gagatttcaa aacggagttc gtcaatgtct ggaaactccg
     6961 tttttcaggt ggcaactgct tccaaccata atcataggaa ggaaaatact gaattttccc
     7021 ttgttcattg ataaaattct tagcataaac atcataacgg ccagcaaaca cagaggtaaa
     7081 caattgtaat ttttcttgcg tcgtcaagcg actactttga agttggaaca tctcctcgaa
     7141 ctgagagcgt tccataacaa actgactctt gtctttaaga cgtttatagt ggaatgaaat
     7201 aagatatgaa caaattgatt aggaaaatca aattaattta tagaaatctt ttagcagtca
     7261 tggcgtccta ttccagattc aaaatgctat acacaagaaa aactcactat ccccattaaa
     7321 agaagaaaag acatcaagga cttctaccac aattccatcc aaagacacaa aaacagccat
     7381 aagagtcacc tccttgattc ctataggctg attataacaa gactggctga aattgtacat
     7441 gaaaataaaa tcctaatagt actcattttg tatgtgacta atattccgtc tcgctccaga
     7501 aggtacgaag taaatagagt ttaaacgagc agtctataaa attcaaaaaa cgcatattat
     7561 caagcgacct aaaactttgg gctctataat atttgtagtg ggtaaattcc ctatggatat
     7621 tatggagcct attttgggta gaaaaaaagt cccataagat ctataatgaa aagcgacaaa
     7681 acaactcatt agaaagaatc atatggaaca attacatttt atcacaaaat tactagacat
     7741 taaagaccct ataaaattcc ttaccttgaa acgactggta tgcctactag aattctcctt
     7801 agaaaacgtc gttttaagtg ctatcattgc ttgaaaatga tggtcgctga aacttctatc
     7861 gtcaagaaaa atcaccaaat tcctcgtatt atcaaccaaa agattgcgca aaagttaatt
     7921 gaaaagattt ctatgaccga tattgcccat cagctggcca tttcaacttc aactgtcatt
     7981 cgaaagctca atgacttcca ctttgagtgt aattttagaa atctgcctaa gattatgtct
     8041 tgggacgttg aaacagtccg gggagtgact gtttcaatcg ggagatggag atgagcttta
     8101 ttgcgcaaga ttttgaaaag ctcgatatca tcactgttct tgagggtaga acacaagctg
     8161 tcatccgaga tcactttctt aaatatgata gagccgtccg atgtcgcgtc aaaattatta
     8221 ctatggatat gtttagtcct tactatgact tagctaaaca gcttcgcttt caaatttcta
     8281 ggctcaggct gaaacagtct cccagactgt ttcactcccg aatgctaaaa tcgttcttga
     8341 tcgctttcat attgtacaac atcttagccg tgctatgagt cgtgtgcgtg tccaaatcat
     8401 gaatcagttt catcgaaaat cccatgaata caaggctatc aagcgctact ggaaactcat
     8461 tcaacaggat agccgtaaac tcagcgataa acatttttat cgccctactt ttcgtatgca
     8521 tttaaccaat aaagagattt tagacaagct tttgagctat tcacaagact tgaaacatca
     8581 ctatcagctc tatcaactct tgctgtttca ctttcagaat aaggaaccgg agaaattttt
     8641 cgaacttatc gaggacaatc ttaagcaggt tcatcctatt tttcagactg tctttaaaac
     8701 cttcctcaaa gataaagaaa aggttatcaa cgcccttcaa ctacactatt ctaatgccaa
     8761 actggaagcg accaataatc tcatcaaact tatcaagcgc aatgcctttg gttttcgaaa
     8821 ctttgaaaac ttcaaaaaaa cggattttta tcgctctgaa catcaaaaaa gaaaggacga
     8881 aatttgtcct ttctcgaact tagcttttct tcaacccact acaattgaca aagagccaaa
     8941 ctttgatgat atacgttttc ttgtgagaat atttacttca ttttttccta aaattcaatg
     9001 tttactcagt atttggatta tgaaaaatcg aggtctaaat ctagatacat tttttctgaa
     9061 gacaaatcat tttgaccacc gagcaagaga ttttcaaaaa aagctgttaa aaactcagga
     9121 cgtcgctgta aaatctttgc attatctaat accaaggcat cacgaaaata cttggaatgt
     9181 tgctgaaatg gtatattatc aatatcaaaa ccaaactcac gaagatactg aatcaaaaag
     9241 accgttactg tccgagtgtt tccttcgcga aatggatgaa tctgccagat tcctgaaata
     9301 aaatgctgga tttgtttaac cacatccgcc tgagttagtg tcgcatatgc aacttgtttt
     9361 tcctgattaa aatcataatc taaggtcatt tgaatcatgg agtaatcaga gtacacaaca
     9421 ctttcaccat tcaaaacagg ttcattcttt gtgatattgg tctgacgaaa ttgccccacc
     9481 ggaatagagg gttcaaatat atcttgaaac aactccttat gaatagcaag taaggtcgca
     9541 ggactaaagc taaagcctct tcgagacaat agttctacaa tacgtagaga aaccaagtct
     9601 gcctcttccg tacttgcatc aatagtatgg tgataagccg ttgcatcctc ataaacctgc
     9661 tcataagtca gttctccccg ggactgtttc tcagccaaag attccatata cgctgatggc
     9721 actagattgt caactttctg cagaccaaaa cctatccgcc ataaatcacg cttcgcttca
     9781 taagacaagt ttggattgtc aatgttgtaa gttggttgca tagaaatatc ctttcaattg
     9841 tttttcttca ttaccagtaa atcacgaaat tggttggaaa ctggcttaaa ctataaaaag
     9901 tcctcacaat aggttctatg atatatatat atatatactt catgtaaata ataaaagagt
     9961 tataatcagc actactgata aattcaatac cgatttcgcc atcttaaaac ttagtcaaac
    10021 gaataccgtt gatttccagt tcattaagtc gttgacctgt caagacttct cgttccttca
    10081 actggaaaag ttaaggggga actaatacaa atcctctacg cttctatatt caatgatttc
    10141 atttttgata atattctttt taaactcaaa atgttttaaa ggattatcga ttaacactaa
    10201 ctttggaata tcatctagat ttgtgaccaa ggataaaata aaatccgatt gaaactcctt
    10261 gactttttca aattcttttg cagttaaacg cacacgcccc ttagattttc ggataccttt
    10321 tacttcggca aggtaagaat actcttggac atctacctga aagtcatatc catcaccata
    10381 aagacgggca tcggttaact gtccaccttg gaatttttct tctttatcaa aatgaaggat
    10441 aaaataattc tcagcctcca ttcccgtttc ctgtagacgt ttgaatttag ttcgaactat
    10501 tggtttttca acgatggtta tgcctgtttt cttcccttca ctggcaagta acattttaac
    10561 tatttcagca taactatgaa catcttcatt tccaaacatc atatcaatta aatctttacg
    10621 aaaacgataa acttcagctt tctgccacca accttttcga ttattgtcaa aataaggatc
    10681 aaataaatcc attctatttt ttacaactcc agttgtttca gcaattccca gagaaaccac
    10741 atagcgataa aactccgact tgctaaagca ttgaaattct tttataaaaa gcttgtcaaa
    10801 cttggcaaga ccgtagccaa ttaaatttaa caattcataa tgagggtgtt tggacatcac
    10861 tttctccatc aatagatatt gatttcatta taccaaaaaa cacggctcat caccgtgttt
    10921 ctgtgtttat ttcaccaact tcttcatctc atcaatacgt gctacggtca catcatactt
    10981 ggcttggtag tcggcttgtt tgtctttttc tttttggaca acttctggtt tagcgttggc
    11041 gacgaagcgt tcgttagaga gtttcttacc aaccatgtcc agttcttttt gccatttagc
    11101 gagttctttg tcgagacgag ctagttcttc ttcaacattg aggagatcgg ccagtggcaa
    11161 gaagatttcg gctcctgtaa taacgcttga catagccagt tcaggtgcag ggatggttga
    11221 tgcgatttcc aagtgttctg gatttgtaaa gcgtttgata tagttgacat tgctgttaaa
    11281 gaaggcttcc aagtcactat cgcttgtctt aacaaggatg gtgataggct tgcttggtgc
    11341 tacatttact tccgcacgcg cattccgaac agcacgaatt aagtctttga gactttccac
    11401 accagtgtga gccgcaaggt cttcaaaggc tagattaaca gttgggtatg cagctgtcac
    11461 gatagaacct tctgagattt gtccaaagat ttcctctgtc acgaatggca tgattgggtg
    11521 aaggagacga aggatcttgt ccaaagtgta tagtagaaca gaacgtgtga tgactttctc
    11581 ttcttcgtta tcgctataaa ggacttcctt ggtcaactca acataccagt tggcaaattc
    11641 ttcccaaatg aagttgtaaa ggatatgacc agccacacca aactcgaact tatcaaagtt
    11701 ttcagtaact tttgcaatgg tttcgttgag attgtggaga atccagcggt ccgtcacatt
    11761 accagcctca cctgttgcaa cttttgtgac attgtcatgc gccacatcca gcgtcaaacc
    11821 tccattgttc atgaggatat agcgagaaat gttccaaatc ttgttaataa agttccatga
    11881 agcatccatt ttctcataag agaaacgcac gtcttgtcct ggcgcagaac cgtttgaaag
    11941 gaaccatcga agggcatcgg caccgtattt ctcgataaca tccattgggt caatcccgtt
    12001 accgagagac ttagacatct tgcgtccttg ctcgtcacga atgagaccgt ggataaggac
    12061 gttttggaat ggttgacggc ctgtgaattc caatgactgg aagatcatac gagacaccca
    12121 gaagaagatg atgtcgtaac ctgttaccaa ggttgaagtt gggaaataac gtttaaagtc
    12181 ttctgagtcg acttcaggcc agcccatggt tgaaaatggc cagagggcag aactgaacca
    12241 agtatccaag acgtcttcgt cctgagtcca tccgtcacct tctggagctt cttcgccgac
    12301 atacatttca ccatcagcat tgtaccaggc agggatttgg tgaccccacc aaagctgacg
    12361 agagataacc cagtcgtgga cattttccat ccattgaagg aaggtatcgt tgaaacgagg
    12421 tgggtagaat tcgaccttgt cctctgtgtc ttggttggca atggcgttct tagccaattg
    12481 gtccatcttg acgaaccatt gagtagacaa gcgtggctca actacgacac ctgtccgttc
    12541 tgagtgaccg actgaatgga cacgtttttc gattttgaca agggcaccga tttcttccaa
    12601 cttagcaacg actgccttac gagcttcaaa acgatccatg cctgaaaatt caaaggcaag
    12661 ctcattcata gttccgtcgt cgttcatgac gttgacttgt ggcaagttat gacgttggcc
    12721 aaccaagaag tcatttggat cgtgggcagg tgtgattttc acgacaccag taccaaactc
    12781 aggatctgcg tgctcatctc caacgattgg gatgagttta ttagcgattg gaaggatgac
    12841 gtttttacca atcaagtcct tgtagcgcgg gtcttctgga ttaaccgcaa ccgcaacgtc
    12901 cccaaacata gtctcaggac gagttgtagc aacttcaagg gcgcgtgaac catcttccag
    12961 catgtaattc atgtggtaga aggcaccttc tacatccttg tgaatcacct caatatcaga
    13021 aagggctgtg cgagctgctg ggtcccagtt gatgataaac tcaccacgat agatccagcc
    13081 tttcttgtaa aggtccacaa agaccttacg aacagctttt gacaaacctt cgtcaagagt
    13141 gaaacgctca cgagaatagt ctacagaaag ccccatcttg ccccattgtt ccttgatggt
    13201 agtggcatat tcgtctttcc attcccagac cttcgtcaag aaagactcac gacctaggtc
    13261 ataacgcgta ataccctcac cacgtaagcg ctcctcaacc ttagcctgag tcgcaatacc
    13321 agcgtggtcc atacctggaa gccaaagggt atcaaagccc tgcatgcgtt tttgacggat
    13381 gatgatatcc tgcaaagtcg tatcccaagc gtgaccaagg tgaagtttcc cagttacgtt
    13441 tggtggtgga atcacgattg aataaggctt agccttttga tcgcctgaag gcttgaaaac
    13501 atccgcatca agccattttt ggtaacgacc agcctcaacc tcggctggat tgtatttaga
    13561 tgaaagttct ttagacatgt gtgttctcct taattacttt tattgacaat tttaaccaaa
    13621 ccaatttttg aaagttcaat ataaatctct tcaatttcag caaatgctgc aagtggtgac
    13681 atagtataat ttccaggatt atatttaaga tcatacttgc ttatctttga aatataatac
    13741 ctagagtgtt tcaattttaa tgattccaac tttgatttaa tatctactaa tgtattatgg
    13801 tttaacttta aaaacaactt attataat
//
LOCUS       DAVLBE010000046        13716 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.046, whole genome shotgun sequence.
ACCESSION   DAVLBE010000046 DAVLBE010000000
VERSION     DAVLBE010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13716)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13716)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13716
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.046"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(138..1768)
                     /locus_tag="VXB91_001543"
                     /pseudo
     CDS             complement(138..1768)
                     /locus_tag="VXB91_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
     gene            2061..6971
                     /locus_tag="VXB91_001544"
     CDS             2061..6971
                     /locus_tag="VXB91_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HEV0470966.1"
                     /translation="MKNPFFERRCRYSIRKLSVGACSLMIGAVLFAGPALAEETAVPE
                     NSGANTELVSGESEHSTNEADKQNEGEHARENKLEKAEAASAAKPEEKAGEVVAETPS
                     AEAKPKSDKETEAKPEATNQGDESKPAAEANKTEKEVQPDVPKNTEKTLKPKEIKFNS
                     WEELLKWEPGAREDDAINRGSVVLASRRTGHLVNEKASKEAKVQALSNTNSKAKDHAS
                     VGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDAGHRNGVPVYGTLFFNWSNSIADQ
                     ERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFINQETTGDLVKPLGEKMRQFMLYS
                     KEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYNYQFMQPEGDKVPADNFFANFNWD
                     KAKNDYTIATANWIGRNPYDVFAGLELQQGGSYKTKVKWNDILDENGKLRLSLGLFAP
                     DTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGDKDWYGIANLVADRTPAVGNTFTT
                     SFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWRWWQTSTGEKLRAEYDFTDAYNGG
                     NSLKFSGDVAGKTDQDVRLYSTKLEVTEKTKLRVAHKGGKGSKVYMAFSTTPDYKFDD
                     ADAWKELTLSDNWTNEEFDLSSLAGKTIYAVKLFFEHEGAVKDYRFNLGQLTISDNHQ
                     EPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADFYEVYEKDGDSWKLLTGSSSTTIY
                     LPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTTFEWGMTVQDTSLPRPLAENIVPG
                     ATVIGSTFPDTEGGEGIEGMLNGTITSLSDKWSSAQLSGSVDIRLTKPRTVVRWVMDH
                     AGAGGESVNDGLMNTKDFDLYYKDADGEWKLAKEVRGNKAHVTDITLDKPITAQDWRL
                     NVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMAKAAARSLGNNKVQVGFADVPAGA
                     TITVYDNPNSQTPLATLKSEVGGDLASAPLDLTNQSGLLYYRTQLPGKEISNVLAVSV
                     PKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLRVQYEGGTEDELIRLTHAGVSVSG
                     FDTHHKGEQNLTLQYLGQPVNANLSVTVTGQDEASPKTILGIEVSQEPKKDYLVGDSL
                     DLSEGRFAVAYSNDTMEEHSFTDEGVEISGYDAQKTGRQTLTLRYQGHEVNFDVLVSP
                     KAALNDEYLKQKLAEVEAAKNKVVYNFASPEVKEAFLKAIEAAEQVLKDHETSTQDQV
                     NDRLNKLTEAHKALNGQEKFKEEKTELDRLTGEVQELLAAKPNHPSGSALAPLLEKNK
                     ALVEKVDLSPEELATAKQSLKDLVALLKEDKPAVFSDSKTGVEVHFSNKEKTVIKGLK
                     VERVQASAEEKKYFAGEDAHVFEIEGLDEKGQDVDLSYASIVKIPIEKDKKVKKVFFL
                     PEGKEAVELAFEQTDSHVIFTAPHFTHYAFVYESAEKPQPAKPAPQNTVLPKPTYQPA
                     SDQQKAPKLEVQEEKVAFHRQEHENAEMLVGEQRVIIQGRDGLLRHVFEVDENGQRRL
                     RSTEVIQEAIPEIVEIGTKVKTVPAVVATQEKPAQNTAVKSEEASKQLPNTGTADANE
                     ALIAGLASLGLASLALTLRRKREDKD"
     gene            7061..8257
                     /locus_tag="VXB91_001545"
     CDS             7061..8257
                     /locus_tag="VXB91_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HEV0470967.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            8393..8920
                     /locus_tag="VXB91_001546"
     CDS             8393..8920
                     /locus_tag="VXB91_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEV0470968.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFGFFGWKGLQI
                     GALTAVFSLRESFDESVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETILYVFVRVLETFMGVFVAIIVN
                     YDIDRIRLFLEKKEK"
     gene            8997..9353
                     /gene="glnR"
                     /locus_tag="VXB91_001547"
     CDS             8997..9353
                     /gene="glnR"
                     /locus_tag="VXB91_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HEV0470969.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYENQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            9390..10736
                     /gene="glnA"
                     /locus_tag="VXB91_001548"
     CDS             9390..10736
                     /gene="glnA"
                     /locus_tag="VXB91_001548"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HEV0470970.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTAIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYVAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(10832..10951)
                     /locus_tag="VXB91_001549"
     CDS             complement(10832..10951)
                     /locus_tag="VXB91_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HEV0470971.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
     gene            11496..12815
                     /locus_tag="VXB91_001550"
     CDS             11496..12815
                     /locus_tag="VXB91_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV0470972.1"
                     /translation="MPDTWEWVRFSTLVEIVRGGSPRPIKDYLTSEVDGINWIKIGDT
                     EKGEKYINNVKEKIKKSGLNKTRFVKKGTFLLTNSMSFGRPYILNVDGAIHDGWLAIS
                     NYENSLNKDYLFYILSSNVVYSQFLSLISGAVVKNLNSDKVASILIPLPPLSEQQRII
                     EAIESALEKVDEYAESYNRLEQLDKEFPDKLKKSILQYAMQGKLVEQDPNDESVEVLL
                     EKIRAEKQKLFEEGKIKKKDLDISIVSQGDDNSYYEEVPCEIPESWEWVRLNDITSYI
                     QRGKSPKYSNIPIYPVIAQKCNQWSGFSIDLARFIDPETVHSYQKERLLRDGDLMWNS
                     TGLGTLGRLAIYHENKNPYGWAVADSHVTVIRVLSGVINCHFIYNFLSSPIVQSVIEE
                     KASGSTKQKELLTKTIKEYLIPLPPLPEQSRIVDKIEQFFAHIDALI"
     gene            12872..13669
                     /gene="psrA"
                     /locus_tag="VXB91_001551"
     CDS             12872..13669
                     /gene="psrA"
                     /locus_tag="VXB91_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type DNA invertase PsrA"
                     /protein_id="HEV0470973.1"
                     /translation="MKDFELHLKKAGLAENTVRSYLYGVRFFLENYELKMEDLFEYKG
                     YLLDNFKPKTVNLRLQGVNKYLAFIGHDDLKLKFVKVQQKPFLEDVISHADYLFLKRS
                     LKKDGILKWHFVVWFLGATGARVSELIKLKVEHVEIGYFDIYSKGGKIRRLYIPKKLR
                     NSCLSWLESENRRSGYLFLNKFNEPITARGVAQQLKNYADKYKMNPKVIYPHSFRHLF
                     AKNFLAKYNDIALLADLMGHESIETTRIYLRKTATEQQNIVDKIVNW"
BASE COUNT         4460 a         2423 c         2899 g         3934 t
ORIGIN      
        1 gttttagaaa tagaggtgta ctattctagt ttcaatatac tatatatctg cagaatactc
       61 tttcagtttc attcagccta gtcttgctta ggaaaaagta agaagccatc caattatgat
      121 ggatagcttc ttggttatta gatttgttct gcaaaaacct tttcagcaag gttcatagcg
      181 tggtctgata cacgagtgta gtgtgagatg atgtcgataa agttgacccc agcttgtgtt
      241 gaacattcgc ctttgttgag gcgtttgatg tgggtttttc tgagaacacg ttctatctta
      301 ttgattgctt catgacgttc tacaagactg cgtgcttttt caatatcatt gttttccaca
      361 ctatccagag catctttgat aaagtcacta gtttggcggt aaacttcctc taattctttc
      421 aaggcggcat cagaaaattc aacatttttc cgttgaagat agtcagtcag attgagtaga
      481 gcctccgtgt ggtctccaat ccgttccaaa tcacgggagg aatcaaggat attggtgagc
      541 acttcacttt ctttttggct gagagcttcg cttgaaaggg caatgagata acgtgttaat
      601 tgctcatcga tggtgttaat tgcttcttcg gttttatgcc ctttttcagc aactttttca
      661 tccaagtcaa tgatgtactt ataggaaagg tcaaaggctt tagcagcgta gtttcctaag
      721 tgcaagagct cttttttagc atttcctaga gcgatagatg gggcttgttt gatgaaatgt
      781 tcatcaagat ataagggttc gtatttgaca acctcgtcct ctccaggaat aatcttggtt
      841 acaaagtaag ccagagctcc gataaatgga aattggacaa tggtgttggt aatattaagg
      901 ttccgtgagc aaaggcgatg gtcatttccg gtgctagatt tagcgtagct tcaaaccaat
      961 gaatcaggac agtaaaagga actagaaaaa taacgcagac gactgttccg ataacgttga
     1021 aggcaacatg agctcctgct acccgtttag ctgcaatatt agcccctaaa gaggcaatga
     1081 tggctgtaat ggttgtcccg atattgtcac caaatagaac tggcaaagct ccctgtaggt
     1141 caattagatt gccggcgtag aggttttgta aaatcccaat ggtagccgaa gaagcttgaa
     1201 ttagcaaggt caagccggta ccgacaaaga cacccaaaac aggattctta cttagctcaa
     1261 tcatatagtc cttaaagacc tgtaaatcct tgagtggagc cattgcgccg ctcatgagat
     1321 tgagggcaaa aaagatacca ccgacaccaa agaggatgcg tccgatatta ttgactgtcc
     1381 gatttttcgt aaaaaagaga cagacggcac cgataaagag cataggtagg gcatagttac
     1441 ctaatttaaa accgatgaga aaggatgtga cagttgtccc aatattagca cccatgacaa
     1501 tcccgatagc ctgacgtaag gttaagagac cggcactgac caggccgact gtaataactg
     1561 ttacaccaga actagactga attagagcag tcatcccaat accaaccaga actccaaaga
     1621 aaggattact agtatatttg tcaatgtaaa aacgaaggcg atctccagca gcttgttgca
     1681 aaccgtctcc catggtcttg atgctatata agaatagccc cagaccacct aaaaagtgaa
     1741 ataaaatttc ctgccaatta atggacattt ctttttcctc cgaaaaataa tcgcggaata
     1801 tctcctattc tattttaaag gataaaagta aatctaacaa gtgttaatgt caagtttgta
     1861 aaagaaaatt ataattgata agtgtattat ttttaagagt ttttaacctt attttagatt
     1921 tgtgcaaaca gttattgttt tttgtctaaa aatgttttag gataaaaatg tgattatcat
     1981 ggttctagag tttgataaaa aactacagaa tataaagcgc tttctttaaa acaacaaaat
     2041 caatctttta ggaggagaaa atgaagaatc cattttttga aagacgttgt cgttacagta
     2101 ttcgtaagtt atcagtagga gcctgctcgc tgatgattgg tgctgtttta tttgctggtc
     2161 cagccttggc tgaagaaact gcagttcctg aaaatagcgg agctaataca gagcttgttt
     2221 caggagagag tgagcattcg accaatgaag ctgataagca gaatgaaggg gaacatgcta
     2281 gagaaaacaa gctagaaaag gcagaagcag ctagcgcagc taaaccagag gaaaaagcag
     2341 gtgaggtggt tgcagaaaca ccatctgcag aagcaaaacc taagtctgac aaggaaacag
     2401 aagcaaagcc cgaagcaact aaccaagggg atgagtctaa gccagcagca gaagctaata
     2461 agactgaaaa agaagtccag ccagatgtcc ctaaaaatac agaaaaaaca ttaaaaccaa
     2521 aggaaatcaa atttaattct tgggaagaat tgttaaaatg ggaaccaggt gctcgtgaag
     2581 atgatgctat taaccgcgga tctgttgtcc tcgcttcacg tcggacaggt catttagtca
     2641 atgaaaaagc tagcaaggaa gcaaaagttc aagccttatc aaacaccaat tctaaagcaa
     2701 aagaccatgc ttctgttggt ggagaagagt tcaaggccta tgcttttgac tattggcaat
     2761 atctagattc aatggtcttc tgggaaggtc tcgtaccaac tcctgacgtt attgatgcag
     2821 gtcaccgtaa cggggttcct gtatacggta cactcttctt caactggtct aatagtattg
     2881 cagatcaaga aagatttgct gaagctttga agcaagacgc agatggtagc ttcccaattg
     2941 cccgtaaatt ggtagacatg gccaagtatt atggctatga tggctatttc atcaaccaag
     3001 aaacaactgg agatttggtt aaacctcttg gagaaaagat gcgccagttt atgctctata
     3061 gcaaggaata tgctgctaag gtaaaccatc caatcaagta ttcttggtat gatgccatga
     3121 cctataacta tggacgttac catcaagatg gtttgggaga atacaactac caattcatgc
     3181 aaccagaagg agataaggtt ccggcagata acttctttgc taactttaac tgggataagg
     3241 ctaaaaatga ttacactatt gcaactgcca actggattgg tcgtaatcct tatgatgtat
     3301 ttgcaggttt ggaattgcaa cagggtggtt cctacaagac aaaggttaag tggaatgaca
     3361 ttttagacga aaatgggaaa ttgcgccttt ctcttggttt atttgcccca gataccatta
     3421 caagtttagg aaaaactggt gaagattatc ataaaaatga agatatcttc tttacaggtt
     3481 atcaaggaga ccctactggt caaaaaccag gtgacaaaga ttggtatggt attgctaacc
     3541 tagttgcgga ccgtacgcca gcggtaggta atacttttac tacttctttt aatacaggtc
     3601 atggtaaaaa atggttcgta gatggtaagg tttctaagga ttctgagtgg aattatcgtt
     3661 cagtatcagg tgttcttcca acatggcgct ggtggcagac ttcaacaggg gaaaaacttc
     3721 gtgcagaata tgattttaca gatgcctata atggcggaaa ttcccttaaa ttctctggtg
     3781 atgtagccgg taagacagat caggatgtga gactttattc tactaagtta gaagtaactg
     3841 agaagaccaa acttcgtgtt gcccacaagg gaggaaaagg ttctaaagtt tatatggcat
     3901 tctctacaac tccagactac aaattcgatg atgcagatgc atggaaagag ctaacccttt
     3961 ctgacaactg gacaaatgaa gaatttgatc tcagctcact agcaggtaaa accatctatg
     4021 cagtcaaact atttttcgag catgaaggtg ctgtaaaaga ttatcggttc aacctaggac
     4081 aattaactat ctcggacaat caccaagagc cacaatcgcc gacaagcttt tctgtagtga
     4141 aacaatctct taaaaatgcc caagaagcgg aagcagttgt gcaatttaaa ggcaacaagg
     4201 atgcagattt ctatgaagtt tatgaaaaag atggagacag ctggaaatta ctaactggct
     4261 catcttctac aactatttat ctaccaaaag ttagccgctc agcaagtgct cagggtacaa
     4321 ctcaagaact gaaggttgta gcagtcggta aaaatggagt tcgttcagaa gctgcaacca
     4381 caacctttga gtgggggatg actgtccaag acacaagtct tccaagacct ctagcagaaa
     4441 acatcgttcc aggggctact gttatcggaa gtaccttccc agatacagaa ggtggagaag
     4501 gtattgaagg tatgttgaac ggtaccatta ctagcttgtc agataaatgg tcttcagctc
     4561 agttgagtgg tagtgtggat attcgtttga ccaagccacg taccgttgtt agatgggtca
     4621 tggatcatgc aggggctggt ggtgagtctg ttaacgatgg cttgatgaac accaaagact
     4681 ttgaccttta ttataaagat gcagatggtg agtggaagct agctaaggaa gtccgtggca
     4741 acaaagcaca cgtgacagat atcactcttg ataaaccaat cactgctcaa gactggcgct
     4801 tgaatgttgt cacttctgac aatggaactc catggaaggc tattcgtatc tataactgga
     4861 aaatgtatga aaagcttgat actgagagtg tcaatattcc gatggccaag gctgcagccc
     4921 gttctctagg caataacaag gtacaagttg gctttgcaga tgtaccggct ggagcaacta
     4981 ttaccgttta tgataatcca aattctcaaa ctccactcgc aaccttgaag agcgaagttg
     5041 gaggagacct agcaagtgca ccattggatt tgacaaatca atctggtctt ctttattatc
     5101 gtacccagtt gccaggcaag gaaattagta atgtcctagc agtttccgtt ccaaaagatg
     5161 acagaagaat caagtcagtc agcctagaaa caggacctaa gaaaacaagc tacgccgaag
     5221 gggaggattt ggaccttaga ggtggtgttc ttcgagttca gtatgaagga ggaactgagg
     5281 acgaactcat tcgcctaact cacgcaggtg tatcagtatc aggttttgat acgcatcata
     5341 agggagaaca gaatcttact ctccaatatt tgggacaacc agtaaatgct aatttgtcag
     5401 tgactgtcac tggccaagac gaagcaagtc cgaaaactat tttgggaatt gaagtaagtc
     5461 aggaaccgaa aaaagattac ctagttggtg atagcttaga cttgtctgaa ggacgctttg
     5521 cagtggctta tagcaatgac accatggaag aacattcctt tactgatgag ggagttgaaa
     5581 tttctggtta cgatgctcaa aagactggtc gtcaaacctt gacgcttcgt taccaaggtc
     5641 atgaagtcaa ctttgatgtt ttggtatctc caaaagcagc attgaacgat gagtacctca
     5701 aacaaaaatt agcagaagtt gaagctgcta agaacaaggt ggtctataac tttgcttcac
     5761 cagaagtaaa agaagctttc ttgaaagcaa ttgaagcggc cgaacaagtg ttgaaagacc
     5821 atgaaactag cacccaagat caagtcaatg accgacttaa taaattgaca gaagctcata
     5881 aagctctgaa tggtcaagag aaatttaagg aagaaaagac agagcttgat cgtttaacag
     5941 gtgaggttca agaactcttg gctgccaaac caaaccatcc ttcaggttct gccctagctc
     6001 cgcttcttga gaaaaacaag gccttggttg aaaaagtaga tttgagtcca gaagagcttg
     6061 caacagcgaa acagagtcta aaagatctgg ttgctttatt gaaagaagac aagccagcag
     6121 tcttttctga tagtaaaaca ggtgttgaag tacacttctc aaataaagag aagactgtca
     6181 tcaagggttt gaaagtagag cgtgttcaag caagtgctga agagaagaaa tactttgctg
     6241 gagaagatgc tcatgtcttt gaaatagaag gtttggatga aaaaggtcaa gatgttgatc
     6301 tctcttatgc ttctattgtg aaaatcccaa ttgaaaaaga taagaaagtt aagaaagtat
     6361 ttttcttacc tgaaggcaaa gaggcagtag aattggcttt tgaacaaacg gatagtcatg
     6421 ttatctttac agcacctcac tttactcatt atgcctttgt ttatgaatct gctgaaaaac
     6481 cacaacctgc taaaccagca ccacaaaaca cagtccttcc aaaacctact tatcaaccgg
     6541 cttctgatca acaaaaggct cctaaattgg aagttcaaga ggaaaaggtt gcctttcatc
     6601 gtcaagagca tgaaaatgct gagatgctag ttggggaaca acgagtcatc atacagggac
     6661 gagatggact gttaagacat gtctttgaag ttgatgaaaa cggtcagcgt cgtcttcgtt
     6721 caacagaagt catccaagaa gcgattccag aaattgttga aattggaaca aaagtaaaaa
     6781 cagtaccagc agtagtagct acacaggaaa aaccagctca aaatacagca gttaaatcag
     6841 aagaagcaag caaacaattg ccaaatacag gaacagctga tgctaatgaa gccctaatag
     6901 caggcttagc cagccttggt cttgctagtt tagccttgac cttgagacgg aaaagagaag
     6961 ataaagatta aatatcgaaa aatcttgtga aatctttcct tatatttcta aagtgtgata
     7021 taatagtttc gaataaaata aataaaggag tttttgtaac atggcaaaac ttactgttaa
     7081 agacgttgac ttgaaaggta aaaaagtcct cgttcgtgtt gacttcaacg taccattgaa
     7141 agatggcgta atcactaacg ataaccgtat cacagcagct cttccaacta ttaagtacat
     7201 catcgaacaa ggtggacgtg caattctttt ctctcacctt ggacgtgtga aagaagaagc
     7261 tgataaagct ggtaaatcac ttgctcctgt agcagctgac ttggcagcaa aacttggtca
     7321 agatgttgtt ttcccaggtg tcactcgtgg tgctgaattg gaagcggcaa tcaacgctct
     7381 tgaagatgga caagttctct tggttgaaaa cactcgttac gaagatgttg acggcaagaa
     7441 agaatctaaa aacgatcctg aacttggtaa atactgggca tcacttggag atggtatctt
     7501 cgtaaacgat gcattcggta cagctcaccg tgcacacgca tctaacgttg gtatctcagc
     7561 aaacgttgaa aaagcagttg ctggtttcct tcttgaaaac gaaattgcct acatccaaga
     7621 agcagttgaa actccagaac gtccattcgt ggctatcctt ggtggttcaa aagtttcaga
     7681 caagatcggt gttatcgaaa acttgcttga aaaagctgat aaagtcctta tcggtggtgg
     7741 gatgacttac acattctaca aagcacaagg tatcgaaatc ggtaactcac ttgtagaaga
     7801 agacaaattg gatgttgcga aagctcttct tgaaaaagca aatggtaaat tgatcttgcc
     7861 agttgactca aaagaagcta acgcatttgc tggttacact gaagtgcgtg acactgaagg
     7921 tgaagcagtt tctgaaggct tccttggtct tgacatcggt ccaaaatcta tcgccaaatt
     7981 tgacgaagct ttgactggtg ccaaaacagt tgtatggaac ggacctatgg gtgtatttga
     8041 aaacccagat ttccaagctg gtacaatcgg tgtgatggac gctatcgtga aacaaccagg
     8101 agttaaatca atcatcggtg gtggtgactc agctgccgca gcgattaacc ttggccgtgc
     8161 agacaagttc tcatggatta gtacgggtgg tggagcatca atggaacttc ttgaaggtaa
     8221 ggttcttcca ggacttgcag ccttgacaga aaaataagat tttataaaca aatcaaagaa
     8281 gagagggatg aaagttcctc ttttcttttg cttaaaataa aaacgcttcc tctcaactat
     8341 tactcataaa aatcaccgat ttatgataaa atggaaatag aaagttgaga ttatgagtta
     8401 ttttaaaaaa tataaattcg ataaatccca gttcaaactt ggtatgcgaa cctttaaaac
     8461 aggtattgct gtttttctag ttctcttgat ttttggcttt tttggctgga aaggtcttca
     8521 aattggtgct ttgacagccg tttttagcct gagggagagt tttgatgaga gtgttcattt
     8581 tgggacttcg cgtattctag gaaatagtat cggtggactc tatgccttgg tcttcttctt
     8641 attaaatacc tttttccacg aagccttttg ggtgaccttg gtagttgttc caatctgcac
     8701 catgttaacc attatgacaa atgtagccat gaataacaaa gcaggggtta ttggtggtgt
     8761 agcagctatg ttaattatta ccctatcaat tccaagtggt gagacaattt tgtacgtgtt
     8821 tgtgcgtgta ttagaaacat ttatgggagt ttttgtcgca attatcgtaa attacgatat
     8881 tgatcgtatt cgtctctttt tagagaaaaa agaaaaataa tgttacattt tataacatta
     8941 ttaattgacg tttgtctttt tttagactat aatagacaga aagaaggaaa ttgtaaatga
     9001 aggaaaaaga atttcgccga aatatggctg tttttcctat cggcagtgtt atgaagttga
     9061 ccgatctatc ggcgcgtcag attcgttatt atgaaaatca agagttgatc aagcccgatc
     9121 gaaacgaagg aaatcgtcgc atgtattcct tgaatgacat ggatcgtctg cttgaaatca
     9181 aagattatat ctctgaaggt tataatatcg ctgccattaa gaaaaaatat gctgaacgtg
     9241 aagcgaaatc caagaaagcg gttagtcaga ctgaagtacg tcgtgcactt cacaatgaac
     9301 tcctccaaca ggggcgtttt gcttcagtac agtcaccttt tggtcgcggt taggcaaccg
     9361 caagtagtca tagattaagg agaaaactta tgccaatcac agctgcagat attcgtcgtg
     9421 aagtcaagga aaaaaatgtt acctttattc gtcttatgtt ctcagatatt ttgggaacca
     9481 tgaaaaacgt cgaaattcct gctacagatg aacagttaga taaggtcttg tcgaacaagg
     9541 ttatgtttga tggatcttct attgaaggtt ttgtacgtat caatgagtcg gatatgtact
     9601 tgtacccgga cttggataca tggacagtct tcccttgggg agatgaaaat ggaagtgttg
     9661 caggtctgat ctgtgatgtt tatacaacag aaggtgaacc atttgcgggt gaccctcgtg
     9721 gtaatttgaa acgagctctt cgtcacatgg aagaagttgg attcaaatcc ttcaaccttg
     9781 gtccagagcc agaattcttc ctatttaagt tggatgaaaa tggggaccca acacttgaag
     9841 tgaatgacaa gggtggctac tttgatttgg cacctactga ccttgcggac aacacacgtc
     9901 gtgagattgt gaatgtcttg accaaaatgg gatttgaagt agaagcgagt caccacgagg
     9961 ttgcggttgg acagcatgag attgacttta agtacgatga agttctccgt gcttgtgata
    10021 agattcaaat ctttaaactt gttgttaaaa ccattgctcg caaacacgga ctttacgcaa
    10081 catttatggc gaagccaaaa tttggtattg ctggctcagg tatgcactgt aatatgtcct
    10141 tgtttgatgc agaaggaaat aacgccttct ttgatccaaa tgatccaaaa ggaatgcagt
    10201 tgtcagaaac agcttaccat ttcctaggcg gtttgatcaa gcatgcttac aactatactg
    10261 ccatcatgaa cccaacagtt aactcataca aacgtttggt tccaggttat gaagcgcctg
    10321 tttacattgc ttgggctggt cgtaaccgtt cgccacttgt gcgcgtacct gcttcacgtg
    10381 gtatgggaac tcgtcttgag ttgcgttcag tggatccaat ggcgaaccct tacgttgcta
    10441 tggctgttct tttggaagtt ggtttgtatg gtattgaaaa taaaatcgaa gcaccagctc
    10501 ctatcgaaga aaatatctac atcatgacag cagaagagcg caaggaagct ggtattacag
    10561 accttccatc aactcttcac aacgctttga aagctttgac agaagatgaa gtggttaaag
    10621 ctgctctcgg agatcacatc tatactagct tccttgaagc caaacgaatc gaatgggcaa
    10681 gttatgcaac cttcgtttca caatgggaaa ttgataatta tttagacctt tactaatact
    10741 aatatagaag aaagattgcc tgtgggtaaa cagtcacaca gcagtctaag ccatcaaata
    10801 cctataaccc ttaaaatagc gatttcggtc gctatttatt tttcgaaaaa tcctcttgac
    10861 tcttttgcga attagattta tcatcagacg tgtagaagaa aattaaggag tcactatgga
    10921 aaaattcaat ttcaaaaaca atatcgggca agaaaacaag ttacttcaaa tcgaaatcta
    10981 caagtttact aacttttgca agcttcaaaa ttacacatct gtaaatattt tttcgaaaga
    11041 tatatttgaa gccatagtaa attgagacta gaatagtaca ctacatctgc taaaaatttc
    11101 tagaaactaa tttaactttc ctaatcgatt tgtttacatc ttatttcaat ctactatatt
    11161 atctcaataa atgatgatgg cgactgtttt gtttgtgctt gtcgattttt gaatcctgat
    11221 cgagcggaag aatatttctg ccgaggttgc caaggggaaa atcctgaaga tattgaattt
    11281 tatgatgaac aattacaggc agaaaaggtg gaggttttga atattcgatt ggaagtaaaa
    11341 aattgaatta tctacaatct catcaacaat aaacctattt caaccccatt atctataggc
    11401 gtatttttac gcctttttat atacttgaag cacataagaa acattatggg aagtttgctg
    11461 atggaagcac tcaagaaatt gatgttcctt atgatattcc tgatacttgg gagtgggtga
    11521 ggttttctac attggttgaa attgtcagag gtggctctcc acgaccaatc aaagattatc
    11581 ttacttctga agtagatgga ataaattgga taaaaatagg tgatactgaa aagggtgaaa
    11641 agtatataaa taatgttaaa gaaaaaatca aaaaatcagg gcttaacaaa actagatttg
    11701 taaaaaaagg tacatttttg ttaactaatt ctatgagttt tggtagacct tatattttga
    11761 atgttgatgg tgcaatacac gatggatggt tggctatttc gaactatgaa aactcattaa
    11821 ataaagatta cctattctat attctttcat caaatgtagt ttattctcaa tttctatctc
    11881 taattagtgg agctgttgtg aaaaacttga atagtgataa agttgcttct attcttatcc
    11941 ctctcccccc actatccgaa caacaacgca taatagaagc aatcgaatca gctttagaaa
    12001 aagtagatga atatgctgaa agttataata gactagaaca gctagataaa gaatttccag
    12061 ataaactaaa aaaatctatt cttcaatatg ctatgcaagg aaaattagtt gaacaagacc
    12121 caaatgatga atcagtcgaa gttttacttg aaaaaatacg agcagaaaaa caaaaactct
    12181 ttgaagaagg caagattaaa aagaaagatt tggacatttc tattgtttcc caaggagatg
    12241 ataactctta ttatgaggaa gtaccttgtg aaataccaga aagttgggaa tgggtgaggt
    12301 taaacgatat aacctcctac attcaaagag ggaagtctcc aaaatattca aatattccta
    12361 tataccctgt gattgctcag aaatgtaatc aatggtctgg cttttctatt gacttagcaa
    12421 gatttattga tcccgaaaca gttcatagtt accagaaaga aagattacta agagatggtg
    12481 atttaatgtg gaattcaaca ggtctaggta cgttaggacg attagctatt taccatgaaa
    12541 ataaaaatcc ttatggctgg gctgttgcag atagccatgt tacagttata agagtcttat
    12601 cgggagttat taattgccat ttcatctata attttctttc ctctcctatt gttcagtcag
    12661 ttattgaaga aaaagcgtcg ggtagtacaa aacaaaaaga attattaacg aaaactataa
    12721 aagaatattt aatccccctc ccaccccttc ctgaacaatc cagaatcgtt gataaaatcg
    12781 aacaattttt cgcccatatt gacgcactaa tttagtataa tagttttacg tgcggtggaa
    12841 tttctatcaa acataagata ggagttttac gttgaaagat tttgaattac atttgaagaa
    12901 agctggttta gctgaaaata ctgtgcgttc gtacctttat ggtgttcgat ttttcttgga
    12961 gaattacgaa ctcaaaatgg aagatttatt tgaatacaaa ggatatttat tagacaattt
    13021 taaacctaaa actgtcaatt tgcgactaca aggagtaaat aaatatctgg cttttattgg
    13081 tcatgatgat ttgaaattaa aatttgtcaa agtacagcaa aaaccatttt tagaagatgt
    13141 cattagccat gctgattacc tttttcttaa acgtagtttg aaaaaagatg gtattttaaa
    13201 atggcatttt gtcgtttggt ttttaggtgc aactggggct cgtgtaagtg aacttattaa
    13261 actaaaagta gagcatgtag aaatcggtta ttttgacatt tactcaaaag gtggtaaaat
    13321 tcgtagactg tacattccta aaaaattaag aaatagttgt cttagttggt tagaatcaga
    13381 aaatcgccga agtggttatt tatttttgaa taaatttaac gaaccaatta cagcaagagg
    13441 agttgctcaa cagttaaaaa attatgctga taaatacaaa atgaatccta aagtaattta
    13501 ccctcattct tttaggcatt tatttgctaa gaatttttta gcgaagtata atgatattgc
    13561 cttgcttgca gatttgatgg gacacgaaag tatagaaact actcgaattt atctaaggaa
    13621 aacagctact gaacaacaaa atattgtaga taaaattgtt aattggtaaa aaataacagg
    13681 tggtcaaact gactacctgc tatttttgtg attatg
//
LOCUS       DAVLBE010000047        13448 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.047, whole genome shotgun sequence.
ACCESSION   DAVLBE010000047 DAVLBE010000000
VERSION     DAVLBE010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13448)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13448)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13448
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.047"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            98..1276
                     /locus_tag="VXB91_001552"
     CDS             98..1276
                     /locus_tag="VXB91_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HEV0470974.1"
                     /translation="MTLSKKQLQLRAKILETVYTLGPISRIEIATKTGITPATTSSIT
                     NDLIKENILLELGEDEHDTSVGRKKILLDIQAKRFYYIGCELSEKHFTFALGDNLGNI
                     LKEEKEIVTKQLIQEKGNQLISQTLKQFLNNCSDYEIEAIGIALPGRYLDDYKITTNN
                     PLWQHIDLEMIQSHFDKPLFFSNNVNCMAIGKRLFSRQQNDPNFAYFHFARGMHCSYI
                     YDGNIYGKGNLMIGEIGHTVVSSEGEECSCGRKGCLQTFAGESWLIKKSKILYHQSPY
                     SLLPSLVKNADDIDIQVILTAYQLGDTGIITLIHQALLYLSQTILNISMMIDSQKIYL
                     HSPLLTNQHIIQKLYSEMNYKPKLLYNRLPEVIIEPYNDFTAAHSAIALCLYHTILHS
                     "
     gene            complement(1504..1950)
                     /locus_tag="VXB91_001553"
     CDS             complement(1504..1950)
                     /locus_tag="VXB91_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0470975.1"
                     /translation="MTIRFEEKVSIENAQFVCQWSNSLGKSFQEQWMGPRIPFLLTLQ
                     ALEGVFSIFDEQEFVGFIQKIRLEDSNLHIGRFFINPQKQEQGLGSQALRKFVSLAFE
                     NEDIDSISLNVFEANQRAQNLYQKEGFEIVQMVEAPVRKYSILKLE"
     gene            2020..2679
                     /locus_tag="VXB91_001554"
     CDS             2020..2679
                     /locus_tag="VXB91_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HEV0470976.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLR
                     PLDLIPILSQVFNRFRCRYCKVRYPVWYALFELVLGLLFLLYSWKLLSLGQVVLITAG
                     LTLGIYDFHHQEYPLLVWMTCHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
                     FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLL
                     V"
     gene            complement(2731..3882)
                     /locus_tag="VXB91_001555"
     CDS             complement(2731..3882)
                     /locus_tag="VXB91_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HEV0470977.1"
                     /translation="MFNGRVLKELRLLNGLSRAELAQRINLTEQAIWQFESNETKPKL
                     STKMHLANQFHVDLTYFEQEEESIRFDSSVIAFRNADLATRKTIDIQTMYLHKVDSLI
                     DYFESFVIIPNITIHDLSNVVSESYHKGESIEELALYAREKLGISKDNHDLLYKLERS
                     GIYIVERLINGQADAYSAWSKLGRPYIVLGTNKSSVRRNFDLAHELGHILLHKYKDMN
                     EDGDRLEQEANYFASCFLLPKEEFLVKFEERVGKRVSNPDSYILLKSDLNVSIQALEY
                     RAFKLGLLTPKQHSYFYRQIAQKGYKMIEPLDDQIFVKKPSKVKSILDVVLSNHLVSL
                     ATIMSKQSIRLQFISEIFSVEMKFFDQYQEDRRTDRFDNIIPLYKRNNL"
     gene            complement(3897..4628)
                     /locus_tag="VXB91_001556"
     CDS             complement(3897..4628)
                     /locus_tag="VXB91_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000934015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0470978.1"
                     /translation="MLNQDLFDSLEAQKIVDTLMKGQKDYVDERLEKRETMIVSNGYA
                     WTRPNHIDTAFASADLFEYKLQLAGQTLGYLEFETNTEKYGKVLLIIKGKKRLTNQFP
                     LVQKNKSGYLFEYAQMNTLYLNQHSSYKNDEDSHSFPIQMELVSDEMIQEIEQATKNS
                     NIEKFMILTYEADSENNIISVDVVMPDARTGQLHLIQDLSEYIQSSSYHFEEAKYQDI
                     PNFSELSETEDFEIIPRIEKQEGQK"
     gene            4857..4958
                     /locus_tag="VXB91_001557"
                     /pseudo
     CDS             4857..4958
                     /locus_tag="VXB91_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234126.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
     gene            complement(4930..5706)
                     /locus_tag="VXB91_001558"
     CDS             complement(4930..5706)
                     /locus_tag="VXB91_001558"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HEV0470979.1"
                     /translation="MPKTLTKKLNAIKAAGKGIFVPYIMAGDHEKGLDGLAETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDIALIPLVSLTTGI
                     ERQKELIEGAEGFVYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIKQAVAYQK"
     gene            complement(5699..6922)
                     /gene="trpB"
                     /locus_tag="VXB91_001559"
     CDS             complement(5699..6922)
                     /gene="trpB"
                     /locus_tag="VXB91_001559"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HEV0470980.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDLTGQNLPDALVACVGGGSNAIGLFHPFVEDESVAMYGAEAAGFGVDTEHHAATL
                     TKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            complement(6900..7499)
                     /locus_tag="VXB91_001560"
     CDS             complement(6900..7499)
                     /locus_tag="VXB91_001560"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HEV0470981.1"
                     /translation="MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEAAE
                     LAKLIPADVKKVGVFVSPSRVELLEAIDKVGLDLVQVHGQVAADLFENLPCASIQAVQ
                     VDGNGHVPNSQADYLLFDAPVAGSGQSFDWGQLDTTGLAQPFFIAGGLNEDNVVKAIQ
                     HFTPYAVDVSSGVETDGQKDHEKIRRFIERVKHGISGTK"
     gene            complement(7486..8253)
                     /gene="trpC"
                     /locus_tag="VXB91_001561"
     CDS             complement(7486..8253)
                     /gene="trpC"
                     /locus_tag="VXB91_001561"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HEV0470982.1"
                     /translation="MSQEFLARILEQKAREVEQMKLEQIQPLRQTYRLAEFLKNHQDR
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLNYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNAGATVILLIVAALSEERLKELYDYATELGLEVLV
                     ETHNLAELEVAHRLGAEIIGVNNRNLTTFEVDLQTSVDLAPYFEEGRYYISESAIFTG
                     QDAERLAPYFNGILVGTALMQAENVAQRIKELQIDKG"
     gene            complement(8250..9254)
                     /gene="trpD"
                     /locus_tag="VXB91_001562"
     CDS             complement(8250..9254)
                     /gene="trpD"
                     /locus_tag="VXB91_001562"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HEV0470983.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALK
                     MKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEGYAMEDVRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            complement(9265..9831)
                     /locus_tag="VXB91_001563"
     CDS             complement(9265..9831)
                     /locus_tag="VXB91_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HEV0470984.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMIRDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEDGRAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEKVVK"
     gene            complement(9828..11189)
                     /gene="trpE"
                     /locus_tag="VXB91_001564"
     CDS             complement(9828..11189)
                     /gene="trpE"
                     /locus_tag="VXB91_001564"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HEV0470985.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFSILAY
                     NPVFEIKFENGVLYQNGQVIDRDPLDFLYEVIHKSQHHSELPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYMVFDHKKEKIHVIEDALYSERSQEALEKSLNQV
                     LEELRIPAPNEFEDLDLSPLDFKPHIAPHKFEVMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNSFDFYRNLRVTNPSNYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGVTDEEDKTLATDLLSDEKETAEHRMLVDLGRNDIGRISETASVQVTKYMKVELFRY
                     VMHLTSVVKGRLLAELTAMDALKATLPAGTVSGAPKIRAMRRIYELETEKRGVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
     gene            complement(11736..11813)
                     /locus_tag="VXB91_001565"
                     /pseudo
     CDS             complement(11736..11813)
                     /locus_tag="VXB91_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     misc_binding    complement(11979..12208)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(12420..13421)
                     /locus_tag="VXB91_001566"
     CDS             complement(12420..13421)
                     /locus_tag="VXB91_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV0470986.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
BASE COUNT         3886 a         3016 c         2315 g         4231 t
ORIGIN      
        1 gtaagcaatg aaaagcttaa aaagattaac atctacattt atccatagca aaaaatcata
       61 ggattttaag aatctgacaa ctaggaagaa aactaatatg accttatcta agaaacaatt
      121 acaactacga gctaaaatac tggaaacagt ttacacatta ggtcccattt cacgaattga
      181 aatcgctact aaaacaggaa taacacctgc aacaactagc agtatcacaa atgatctgat
      241 taaagaaaac attctcttag aacttggtga agacgaacac gatacaagcg tagggagaaa
      301 aaaaatcctg ctagacattc aagctaaacg attttactac attggttgtg aactatctga
      361 aaaacatttc acttttgctt taggagataa tctaggaaat atcttaaagg aagagaaaga
      421 aattgttact aaacagttaa tccaagaaaa gggaaatcaa ctcattagcc agacactaaa
      481 gcaattctta aataactgct ctgattatga aatagaagca attggaatcg cgctacctgg
      541 tcgctattta gatgattata aaataacaac aaacaatcct ttatggcaac atatcgactt
      601 agaaatgatt caatcccact ttgataagcc tttgtttttc tctaacaatg ttaactgtat
      661 ggctataggt aaacgcctat ttagtcgcca acagaatgac cctaattttg cttattttca
      721 ttttgctaga ggtatgcact gttcttatat ctacgacgga aacatttatg gaaaaggaaa
      781 tctaatgatt ggagaaatag ggcatacagt tgtttcatct gagggagaag aatgtagttg
      841 cgggcgcaag ggatgcttac aaacttttgc tggagaatct tggttaatca aaaaatcaaa
      901 aattctatat catcaatctc cctattctct acttcctagt ttagtcaaaa atgccgatga
      961 tattgatatc caagttattt taaccgctta tcaattaggt gacactggaa taatcacact
     1021 tatccatcaa gccttactct atcttagtca aaccatttta aatatcagta tgatgattga
     1081 ctctcaaaaa atctacctac atagtccttt actaacaaat caacacatca tccaaaaact
     1141 atatagtgaa atgaactaca aacccaaact gctctataat cgcctacctg aagtcattat
     1201 tgaaccttac aatgatttta cagccgcaca ctcagctatt gcactttgtt tgtatcatac
     1261 aattctacat tcctaatttt ctattacatt taataaatag gctaaaaaga gggagtatat
     1321 cataaaaagc gaacaaacct gttttctgaa aatcagaatt ctgttttgtt cgctttcttt
     1381 atatttggaa ttatactcct atctcccctt tttcataatg tatagtaaaa tgaaataata
     1441 acaggacgaa tcgatcggga cagtcaaatc gatttctaac aatgttttag aagtagaggt
     1501 gtactattct agtttcaata tactatattt tcgtacaggt gcttcaacca tttgaacgat
     1561 ttcaaatcct tctttttggt aaagattctg agctctttga tttgcctcga agacatttag
     1621 agaaatacta tctatatctt cattttcaaa ggccaaacta acaaatttcc ttaaagcctg
     1681 gctacctaag ccttgctcct gtttctgggg gttgataaaa aatctcccga tatgaagatt
     1741 gctgtcttct agcctgattt tctggataaa tcccacaaac tcttgttcat caaagattga
     1801 aaagactcct tccaaggctt gaagggtcag tagaaaagga atccttggtc ccatccattg
     1861 ttcttgaaag gatttgccta gggagttgga ccactggcat acaaattgag cgttttctat
     1921 actcaccttt tcttcaaaac gaattgtcat cttttcctca ccatcttatc tatgtttctc
     1981 cattatacta tttctcccat tttttacgaa tagataagta tgattgattt ttattttttt
     2041 ctcgtcggga gcattctcgc ttcctttctt ggtttggtca ttgaccgttt tccagagcaa
     2101 tccattatca gttcagccag tcactgcgat tcctgtcaga ctcgcttgcg tcccttagat
     2161 ttgattccga ttctctcaca ggtcttcaat cgctttcgct gtcgctactg caaagttcgc
     2221 tatcctgtct ggtatgccct ctttgaatta gtcttaggac tcctctttct gctttactct
     2281 tggaaattgc tttccttggg gcaagtcgtc ctaatcaccg ctggtttgac cttgggtatc
     2341 tacgactttc accatcagga atatccctta ctggtctgga tgacttgcca cctaatccta
     2401 atagcttcct ctggctggaa tctggtcatg gtctccttcc tcatacttgg aattttggct
     2461 cattttatcg atatccgcat gggtgcaggg gatttccttt ttttagcttc ttgtgctctc
     2521 gtctttagcg taacggagtt actgatcttg attcagttcg cttctgcgac gggtatcctg
     2581 gcctttctcc tgcaaaagaa aaaggaaaga cttcctttcg tgcctttcct cttacttgct
     2641 acttgtttga ttatttttgg taagctactg cttgtctaat aaaatccaat ttctgccata
     2701 tgtccttcat gaaattattt cacagttaaa ttataaatta tttcttttgt acaaagggat
     2761 gatgttatca aatcgatctg ttcttctatc ttcttgatac tgatcaaaaa atttcatttc
     2821 gactgaaaat atttcgctta taaactgtaa acgaatactt tgtttagaca ttatagtcgc
     2881 tagactgact agatgattac tcaaaacgac gtccagaata ctctttactt tgcttggttt
     2941 tttaacaaaa atttgatcat ccaaaggttc aatcattttg taaccttttt gcgcaatttg
     3001 acgataaaag taagaatgtt gctttggagt caataatcct aacttaaaag ctcgatactc
     3061 taaagcctgt atcgaaacat tcaaatccga cttcaataaa atataactat caggattgct
     3121 gacacgcttg ccaaccctct cttcaaattt gactaaaaac tcttcttttg gcaataaaaa
     3181 acatgatgca aaataatttg cttcttgctc caaacgatcg ccatcttcat tcatatcttt
     3241 atatttatgt aaaagaatat gtcctagctc atgagctaag tcaaaatttc gacgtacaga
     3301 tgatttattc gttcccaaca caatataagg tcttcccaat tttgaccatg cgctataagc
     3361 atcagcttgg ccattaatta atcgttccac gatatagatg cctgaacgtt ctaatttata
     3421 aagcaaatca tgattatctt ttgaaatacc taatttttcc ctggcataaa gagccaattc
     3481 ctcaatggat tctcccttat gataagattc actcactaca ttacttaggt catgaattgt
     3541 aatattaggt ataattacaa aactttcaaa ataatcaatc aaactatcta ccttatgtaa
     3601 atacatagtt tgaatatcta ttgttttccg tgttgctagg tctgcatttc taaaggcaat
     3661 tacagaagaa tcaaatcgaa tgctctcttc ttcctgttca aaataagtta aatcaacatg
     3721 aaattggttg gccaaatgca ttttggttga taatttaggt ttcgtttcgt tggactcaaa
     3781 ctgccaaatg gcttgttccg ttaaattaat tctctgagct aattctgctc tacttaaacc
     3841 atttaacagc cgtaattctt tcaatacccg accattaaac atttacatac tccttactac
     3901 ttttgacctt cttgtttttc tattcttgga ataatttcaa aatcttctgt ttccgataat
     3961 tctgaaaaat taggaatatc ttggtattta gcttcttcga aatggtacga acttgattga
     4021 atatactcag acaaatcttg aatcaagtgt aactgaccag ttcgtgcatc aggcataaca
     4081 acatctacag atataatatt gttttctgag tccgcctcat aagttaaaat cataaatttt
     4141 tcgatattcg aatttttggt agcttgttca atttcttgaa tcatttcatc agaaactaac
     4201 tccatctgaa ttggaaagga atgactatct tcatcatttt tgtaggaaga atgttgatta
     4261 agataaagtg tattcatttg agcatattca aataagtagc cactcttatt tttttgtacc
     4321 aaaggaaatt ggttcgtaag tcgcttctta ccctttataa ttaacaatac tttcccatat
     4381 ttttctgtat ttgtttcaaa ttctaaatat cccaaagtct gtcctgctaa ttgtaattta
     4441 tactcaaaca aatctgctga tgcaaatgca gtatcaatat gattaggtcg cgtccatgca
     4501 taaccattcg acactatcat tgtctctctt ttttctagac gttcatctac ataatctttt
     4561 tgccctttca tcaaagtatc tacaattttt tgtgcctcaa gcgaatcaaa gagatcctga
     4621 ttcaacataa ttcttcctcc tccaaatact ttttaatgaa ttatatcatt ttcttaaaga
     4681 aattactaca ataattagct ttttcttaaa gttctgtgtc agagtaattt agaaaattat
     4741 atcttctata gtaaaatcaa ttaaaaactg aacaaattta ttgggaaatt caaatcactt
     4801 tcttaaaata ttttaggaac cgtagtgtaa tattccagat tcaattcact ataaaactag
     4861 cctttctcct gcaaaagaaa aaggaaagac ttcctttcgt gcctttcctc ttacttgcta
     4921 cttgtttaat tatttttggt aagctactgc ttgtttgata aagtcctgaa tcggctctcc
     4981 ttggtggaga gcttttacta ttttcgaacc gacgataaca ccatctgaca ccgcattgaa
     5041 gcgttccaga tcggcttgac tagatacacc aaaacctgtc aagactggga tgtcggccac
     5101 ttgatgaagt tgcgccaagt gcttgtccaa atctgcacgg taattgcctg atttccctgt
     5161 taccccattg atggcaacgg catagacgaa tccctccgcc ccttcaatca actctttctg
     5221 gcgctcaatt cctgtggtca agcttactaa aggaatcaag gcgatatctg tatctgccaa
     5281 aaatggttct acaaagttgg catgttcatg aggcaggtct gggataatca agcccttcac
     5341 agctgtatca gccagatctt tgacaaagtt ctccacaccg tactgaaaga gggggttgaa
     5401 gtaggtcatg atgaccagtg gaatctctgt ttcaatggtt ttcaaggttt caactaaagc
     5461 ctgggtagag gtcccgtggg ctaaactgcg caagccagct tcttcgataa caggtccatc
     5521 tgcaacaggg tctgaaaagg gaatacccac ttcaattgca gagacaccca aatcttctaa
     5581 aaagtgaatt gtttcagcaa gaccatccaa acctttttcg tggtcaccag ccatgatata
     5641 gggaacaaaa attccttttc cagctgcttt aatagcattt aatttttttg ttagtgtctt
     5701 aggcatgagc ttctcccttc tttgctgcat ctgcttccaa gcggtctttt acttgaacca
     5761 catccttgtc cccacgacct gataggcata caatcataga cttttctggt ccaagttctt
     5821 tggccaattt caccgcaaag gcgatagcat ggctagattc caaagctggg ataatccctt
     5881 ccacacgaga caagagttgg aatccttcca aggcttcttc gtctgtcaca gggacatagc
     5941 tggcacgttt aatatcgtgg tagtgagaat gctctggacc gataccagga tagtccaaac
     6001 ctgctgagat agagaaggct tcaagaattt gaccatgggc atcttggagc acatccatga
     6061 gggaaccgtg aaggacacct ggacgaccct tggtcaaggt agctgcgtgg tgctccgtat
     6121 ccacaccaaa tccagccgct tcagctccat acatggctac tgactcatct tctacaaagg
     6181 gatggaagag accgatggca ttcgacccac caccaacaca ggctactagg gcatctggca
     6241 gattttgtcc tgtcaagtca cggtactgtt gtttagcctc tcgaccaatg acactttgga
     6301 agtcacgaac aatttctgga aatggatgag gccccaaggc agaaccaagg atatagtggg
     6361 tatcatctat attagccacc catgaacgaa gggctgcatt gaccgcatcc ttgagcacgc
     6421 gcgaaccatc tgtcacggcc tcgaccttag ctcccaaaag ctccatacgg aagacattga
     6481 gggcttggcg tttgacatct tcctcaccca tgtagatggt acattccatg ttaaagaggg
     6541 ccgcagcagt tgcagttgcc acaccgtgct gaccagcacc agtttctgcg ataattttct
     6601 ttttacccat gcgtttggca agccaaactt gtcccaaggc attgttaatc ttgtgggctc
     6661 ctgtatggtt aaggtcttcc cgtttgagat aaatcttggc tccgccgata tgctgggtca
     6721 agttttttgc gtaataaaga ggagtttcac gtcctacgta ctggcgcaaa agctggttta
     6781 attcctcttg gaaacttggg tctgcctgac tttcacggta ggccttctcc aactccaaaa
     6841 ctgctgtcat caatgtttct gggacaaaac gtccgccgaa ttttccgtaa aatccatctt
     6901 tatttggttc ctgatatgcc atgctttacc ctctctataa atcttctaat cttttcatga
     6961 tctttttgtc catctgtctc cactccgctc gatacatcta ctgcataggg agtaaaatgt
     7021 tgaattgctt ttactacatt atcttcatta aggccacctg cgataaagaa gggctgtgct
     7081 agtccagtcg tatccagttg accccaatca aaggactgac cacttcctgc cacaggggca
     7141 tcaaagagta gataatctgc ctgagaattg gggacatgcc catttccatc tacctgcaca
     7201 gcctgaatac tggcacaagg caaattctca aataaatcag ctgccacctg accgtgaact
     7261 tgaaccaagt ccaagccaac tttgtcaatc gcttccagca gttctacccg acttggtgaa
     7321 acaaatactc caaccttttt cacatctgca ggaataagct ttgccaactc agctgcctct
     7381 tctaaagtca cctgtctttt actaggtgca aagacaaaac cgatatagtc ggctcctgct
     7441 gaaacggctg tttccaccgc ttctttggtc gatagtccac aaattttaac ctttgtcaat
     7501 ctgcaactcc ttgattctct gggccacatt ttctgcctgc ataagagctg tccctaccaa
     7561 aattccgtta aagtatgggg ctagtcgttc cgcatcctgc cctgtgaaaa tggcagattc
     7621 agaaatgtaa tagcgacctt cctcaaagta aggggctaaa tctacactgg tctgcaagtc
     7681 gacctcaaag gtagtcaagt tgcggttgtt gaccccgata atctcagcac caagtctgtg
     7741 ggctacctct agttcagcta gattgtgagt ctccactaag acttccagac caagctctgt
     7801 cgcgtagtca tacagttcct tgaggcgttc ttcggacaag gctgccacaa taagcaagat
     7861 aactgtcgca cctgcattgc gagcgcggat gatttgcttt tcatctatga taaagtcttt
     7921 gttgagcgtc ggaatctcta cctgactgga aatttcccgt agataattca aatgcccttt
     7981 aaagaaaacc tcatctgtca acaccgaaat catcactgct ccgttttctt cataagtctg
     8041 ggcctgttgc acaatatcca catcgagatt gatatctccc aaactagggc tagctttctt
     8101 gacctcagcg attacctgca agcggtcctg atgattcttc aaaaattctg ccaagcgata
     8161 ggtctggcgc agaggctgga tttgctccag cttcatttgc tccacctcac gcgccttctg
     8221 ctctaagatt cgtgctaaaa attcctgact catttttgat actcctgtaa cagtctgagt
     8281 ttttcaaggg ccttgcctct agcaatcact tgacgggcca aggcaactcc ttccttgatg
     8341 ctatcaatct taccattagc atagaaacca agaccagcat tcaagactgt cgtttccaag
     8401 aatggacttg cttcgttttt cagaacgcta agcaaaattt ctgcattttc ctgagcattc
     8461 ccaccacgaa catcttccat agcatagcct tccattccca aatcctctgg agtaaagctt
     8521 gacaagctga tttcgccatt ttcaagaagt gcaatcttgg ttgttccgtt caagccagct
     8581 tcatccaacc cttctggtcc agcaaccacg atggcacgtt tgcgacccat atttttcaaa
     8641 acctgagctg tactttctag gagttctgga cgactaattc caagaagctg tgtttctaaa
     8701 gccattggat gaatcagtgg accagtcaag ttcataatcg ttggaattcc caattccaaa
     8761 cgagctggca tgatgtattt catagctggg tgcatatttt tagcgaagag aaagacgatt
     8821 ccagttttat caaagacctt acctagttca gctggtttga ggtcaagatt gattcccaag
     8881 gcttcgagga catctgcgga accagattta gaagaaatcg agcggttacc atgcttggcc
     8941 atgtgaatac cgccaccagc caagacaaag gctgcagttg tggaaatatt aaaactgaaa
     9001 gacttgtccc cacctgtacc acagttgtcc atggcatcat gaatctcagt tggaatatgc
     9061 tgggcatgtc ctctcatgac ttgggcaatg gctgtgcgtt cttcaggtgt ttcccccttc
     9121 atcttaagag ctaagaggag agaagcaatc tgcgcttcag ttacacgccc agttacgata
     9181 cgctcaatga catccgtcat ttccacacct gataaatttt caaattttgc tagtttttca
     9241 ataatctctt tcatcctagt ttcctcactt tacaaccttc tcgataaaat tccgaataga
     9301 agacaagccg tctggcgttc caatgctctc tggatggtac tggaagccat aaatcggtag
     9361 gtttttatgt tgaatcccca tgatggcttg gtcatcagtc gaacgagctg tcacttcaaa
     9421 gtcttctggc atttcctcaa tcaaaatact gtgataacgc atgaccgcac gtccatcctc
     9481 aataccttga tacaaaacag atggcgcttc aaagttgata ttgctctgtt tcccatgcat
     9541 gacttttgga gccaaaccta gcttaccacc aaagacttct gcaatggctt ggtggcccaa
     9601 acaaatccct agaatcggct tcttgcctgc aaaatcacga atcatgtctt ccatctttcc
     9661 agcatcaact ggccaaccag gaccaggaga aaagaccaga ccatctgctt tttcagcttc
     9721 ttcatacagc ttggaatcat catttctcag aacctgaact tctgcaaaat tcccaatgta
     9781 ttgggccaag ttataggtaa aagaatcata gttgtcaatc aataaaatca tggtcttagt
     9841 tctccaattc tagtcataga ttttgctttg ttaatggttt cttggtattc gttttgggcg
     9901 atagagtcgt agacaatccc tgccccagcc tgcacatagg ctctttgatt tttgagaatc
     9961 atggttcgga tggcaatggc caaatccata tcacccgtcg cagacaagta gccgattgct
    10021 cctgcatata cgccccgttt ttccgtttcc agttcataga tgcgtctcat cgcccgaatc
    10081 tttggtgctc cagaaacggt tccagcagga agcgttgctt tcaaggcatc catggcagtg
    10141 agttctgcaa gcaaacgccc cttgaccacg ctggtcaaat gcatgacgta gcggaagagc
    10201 tccaccttca tatacttagt aacttggaca ctggccgttt cagagatgcg gccaatatcg
    10261 ttacgcccca agtctaccaa cattcgatgt tctgctgttt ccttctcatc agagaggagg
    10321 tcagtcgcca aggtcttgtc ttcttcatcc gtaacccctc ttggtcgcgt ccctgcaatc
    10381 ggattggttg tcacgatgcc atttttgaca gaaactaaac tttctggact agctccgatg
    10441 atttgataat ccccaaaatc atagaaatag aggtaattgg atggattggt cacgcggaga
    10501 tttctgtaga agtcaaatga atttccagta acttctgctg agaaacgctg gctgagtaca
    10561 cattggaaca tatcaccatt acgaatcaag tcacgagctg tttctaccat tacctcaaac
    10621 ttatgtggag cgatatgcgg tttgaagtca agtggtgata aatccaagtc ttcaaattca
    10681 tttggagcag gaatgcgtaa ttcctcaagc acttggttca aggatttttc caaggcctct
    10741 tgactgcgct cactatagag agcatcctct atgacatgta tcttctcctt cttgtggtca
    10801 aagaccatat agctctcata gacaaagaaa tgcatgtctg gcgtcccaat tgtatcctca
    10861 gggatttgac caatttcttc ataaagcgaa atcatatcgt aacccacaaa accaatggct
    10921 ccaccaccaa aaggtagctc tgagtggtgc tgactcttat gaatcacttc ataaaggaaa
    10981 tccaagggat ctcgatcaat cacttgacca ttttgataaa gaactccatt ttcaaactta
    11041 atctcaaaaa caggattata ggctaagata gaaaaacgag ctgtttcctt gtctctcgga
    11101 atactctcta agataacctt gtgttgcccc tttaagcgca tataagccaa gattggtgat
    11161 aagacatctc catgaatgat tcgttccatt gtaatttccc tttcagttct acttctagtc
    11221 cgtggtgact gtatgaaaaa tccccacgca aaataacttg cgtgaggacg aaattcgcgg
    11281 tgccacctca attataggat ttctcctatc tctcattcct gtctcagata cctcctgtaa
    11341 caggctgtgc gataaagggc actcccttga gaatgatgtt ttcttctctc gtttcagatg
    11401 aacccaactt tacagctttc tctgcttgtt ttcagcaacc acaagctctc tgtgagagaa
    11461 aagactgtaa tttttccatc tattattttt tagcttctag gtaatctgca atcgcagcta
    11521 ggtccttgcc tccacgacca gagatattga tgaggagatt tttatttcga tacaccttta
    11581 tactcttcga aaatctcttc aaaccgcgtc aacgtcgcct tgccgtaggt atggttactg
    11641 acttcgtcag ttctatctgc aacctcaaaa cagtgttttg agctgacttc gtcagttcta
    11701 tccacaacct caaaacagta ttttgagctg acttcgtcag ttctatccac aacctcaaaa
    11761 cagtgttttg agcaacctgc ggctagtttc ctagtttgct ctttgatttt cattgagtat
    11821 tactagcttt tttcgtatta gtccagcttt ttgtttgctt ttagtagtag gcaaggagct
    11881 gtagatagaa ctcaagttca tcaaagcgac ttaaggccct aataaaagat aaaccaaacg
    11941 acggatagaa aaaagcccac acacaaaata tacttccgtg tgagggcgtt ggtaacgcgg
    12001 tgccacctca attataaagg gactatccct ttacatctct gccttgttta acaacaagct
    12061 gcactgtaag gtgtgcgcac cgaattttca ttgtttcaaa ttcattttca aaatcagccc
    12121 actttcacta cttccaacca cctattcaca accaccacag gctccctgaa gatcaaaaat
    12181 agttactttt ctgatttgtt gaacttattt taatactttg ttttttcttt gtcaagactt
    12241 ttttacgatt tttttgaaaa tatcattcga atgtgaccat gtcttcctta gatcgaacat
    12301 gaacatgtcc cacttgttag aaattggatc caactcaata gaaactgaat ggaggctaaa
    12361 cagaacttat tttagaacac tccatctttt ccactaggat tttcaagaat taaacaatac
    12421 tagaaactct gtctcctaac aaatttagga gaaacttcaa cagatgtgac actttcccct
    12481 ttaataattg ctaaaacacc ttctatcatt tctttagcca atttaacata attgggagca
    12541 attgtagaca aagctggagt ataatactga gaaataggaa tattatcaaa tccaatgata
    12601 gaaatatcat ctggaataag aattcctttc tcatagcacg cacgaatcaa gccctgaacc
    12661 ttttcatctc ctgaaacaaa aataatgtcc ggataatttt gggtagtcaa gtgctgcatt
    12721 gcataagaat aaactgaatc aattgtagat aagccataaa tgacttttaa atccataaag
    12781 taatttttat cattcagaaa agaacgcaca cctctttcac gatccttatt aacatgggat
    12841 tctcctccca taagcaacca catattttta aatttttctt cagttacagc tttcatcata
    12901 tcataagtag cttgaaaatt attattagat acatagacta ctccagacgt ttgagattca
    12961 ccgaaaacaa gaaaaggcat atggttcttc tttaaatact gaattctgat atcatctaca
    13021 ctttcataaa aaacaataac accatctact aggctacctg tgcttgatat aattgaatta
    13081 ctaattgtat cctcctctcc aaagtactca actatagcat taacaccaaa ttctttacac
    13141 gtccgtaaca ctttatctaa cagcgtatga aaccaaatta aaggaaaaga gtcgattttt
    13201 tttacagaaa tcaatatatt tatagcttct tttttagtta aattttttgc atacgcattt
    13261 ggaatatacg acaattcctc tataactttt tgaatcgctt gataagtttc ttctttaaca
    13321 tttactccac cattaataac tcgtgaaact gtttttggag aaaaacctga taaacgtgca
    13381 atatcataaa tagttacctt tttcccattt atatttttca tttcagtcct ccattacgaa
    13441 cattctaa
//
LOCUS       DAVLBE010000048        12908 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.048, whole genome shotgun sequence.
ACCESSION   DAVLBE010000048 DAVLBE010000000
VERSION     DAVLBE010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12908)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12908)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12908
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.048"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(98..610)
                     /locus_tag="VXB91_001567"
     CDS             complement(98..610)
                     /locus_tag="VXB91_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin"
                     /protein_id="HEV0470987.1"
                     /translation="MSAQITINHKKARYVRIGLEGYNALSLAEVEVFRFIATNAETAT
                     QVSKPVQPISQTPVKDKTLTIQHSGAYIARYSITWEEVPVDKDGNQVVRSHSWEGNGC
                     NQTAGFVLNFPIKENMRNLRVKIEKKTGLLWNRWQTIYENRPILAQPHRKITHWGTTL
                     NSKVSDDDVL"
     gene            complement(635..1615)
                     /locus_tag="VXB91_001568"
                     /pseudo
     CDS             complement(635..1615)
                     /locus_tag="VXB91_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855254.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
     gene            complement(2091..2900)
                     /locus_tag="VXB91_001569"
     CDS             complement(2091..2900)
                     /locus_tag="VXB91_001569"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEV0470988.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIGFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRAYTP
                     EYRATAHEVAKKLNIKLDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHSGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL"
     gene            complement(2924..3457)
                     /locus_tag="VXB91_001570"
                     /pseudo
     CDS             complement(2924..3457)
                     /locus_tag="VXB91_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285096.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
     gene            complement(3459..4670)
                     /locus_tag="VXB91_001571"
     CDS             complement(3459..4670)
                     /locus_tag="VXB91_001571"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HEV0470989.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAESNPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFSPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            complement(4684..5367)
                     /gene="rpiA"
                     /locus_tag="VXB91_001572"
     CDS             complement(4684..5367)
                     /gene="rpiA"
                     /locus_tag="VXB91_001572"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HEV0470990.1"
                     /translation="MENLKKMAGIKAAEFVKDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQIIAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRRFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QISTSKKGK"
     gene            complement(5665..6504)
                     /locus_tag="VXB91_001573"
     CDS             complement(5665..6504)
                     /locus_tag="VXB91_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HEV0470991.1"
                     /translation="MKVIDQALLEKVIIERSRTSHKGDYGRLLFLGGTYPYGGAIIMA
                     ALAAVKSGAGLVTVGTDRENIPALHSHLPEAMAFSLQDQQLLKEQLEKAEVVLLGPGL
                     RDDAFGEDLVKQVFAGLRQNQILIVDGGALTILARTSLSFSSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASALTSFPQGTILVEKGSATRIWQAGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFAGQFKQASLYERVAVATHLHSAIAQELAQEQYVVLPTEISNCLPKVMK
                     RYV"
     gene            complement(6518..7339)
                     /locus_tag="VXB91_001574"
     CDS             complement(6518..7339)
                     /locus_tag="VXB91_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATPase"
                     /protein_id="HEV0470992.1"
                     /translation="MILKIYNREYSLQWDGIYYLALIDYPNIQEWELEKIAKFIAYEK
                     LHKRQTSIECADSCLKKEILDYICQHPFLPPFTPTDKRVASTYDLHKRLVTSDYCSHT
                     TTIDAAISIFKTGQLLSAVKAFRRDAEELVLDSRNAASDPIDYFDYVMLGWSNTSSGY
                     RLAMERLLGRAPSEKELQDKFIPGVSFHFIYTDLIKVTGYIFDGYHVAKIKDMLNLFS
                     ELYICIIPTHNKSQFENIIPTKIQDRVHYLDYAGEDLEEWTKKVYQVVLKQSDKG"
     gene            complement(7476..8333)
                     /locus_tag="VXB91_001575"
     CDS             complement(7476..8333)
                     /locus_tag="VXB91_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HEV0470993.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKTAKLKEETALVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGSRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLAIDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIELEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLTHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASYITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            complement(8487..9221)
                     /locus_tag="VXB91_001576"
     CDS             complement(8487..9221)
                     /locus_tag="VXB91_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV0470994.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKLIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVMENI
                     TLSPIKTKGESREVAEKRAQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLSKVL"
     gene            complement(9221..9904)
                     /locus_tag="VXB91_001577"
     CDS             complement(9221..9904)
                     /locus_tag="VXB91_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV0470995.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILII
                     SMNSGAYVSETVRAGINAVPKGQLEAAYSLGIRLKNAMRYVILPQAVKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KHMGQGDKK"
     gene            10094..10324
                     /locus_tag="VXB91_001578"
     CDS             10094..10324
                     /locus_tag="VXB91_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HEV0470996.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            10553..12811
                     /locus_tag="VXB91_001579"
     CDS             10553..12811
                     /locus_tag="VXB91_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEV0470997.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENPSEKDLKAVMTSKGNIQIKSA
                     KKAEVKSSEKEK"
BASE COUNT         3865 a         2915 c         2318 g         3810 t
ORIGIN      
        1 aattttgttc tttcacagag agctacctga gttctattca agctcagata gtactttctt
       61 ataaactaga caaactaact gtcattgtac catcagatta caagacatca tcgtcactca
      121 ccttggaatt caatgtcgta ccccaatggg taattttacg gtggggttga gctaaaattg
      181 gtctgttttc atagattgtt tgccatctat tccatagtag gcccgtcttt ttctcaatct
      241 taactcgcag atttctcata ttttctttga ttgggaagtt gaggacaaaa cctgcagtct
      301 ggttgcaacc gtttccttcc caagaatgac tacgaacaac ttggtttcca tctttatcta
      361 ctggaacttc ttcccaagtt atggagtagc gggcaatgta agctccactg tgttgaattg
      421 tcaatgtttt atctttcaca ggagtctgac tgattggttg aactggctta gaaacttgtg
      481 tcgccgtttc agcattcgta gctataaagc ggaaaacttc aacttctgca agactgaggg
      541 cattatagcc ttctagccca atccgaacat agcgcgcttt tttatggtta atcgtaattt
      601 gtgctgacac atctttagga gatattatac gttttcactc aatttcttta ccagaactgt
      661 ctaaaagaat gacatcaaag tttgccaatc tatcctgggc agtgtctgtt cggttgtaaa
      721 tattgatttg gcgaatggtt tcttctttag ccaaatctac ttgccaccaa ggcttagatt
      781 ggaagtttgt atgagtgaca gaattgtgac catagttacc atcgactttg ccatccacag
      841 ctcttctagc atctcctccg aaagctgtcg aactttgagt aacctgtttt cctaaggcaa
      901 tattttccat tggttcagcg cttggttgac tagaagattg aggtagagcc tgtttcttaa
      961 agaatcgcac tttatccaat ttcggatcac gataaccatg tttatccaag gtagcttgtt
     1021 taccaatatt aaagttagga atatcattca ttggactttc aaaatagcca cgagaacggt
     1081 gtttaaagcg tgaattacct gtaaatgtaa caatatcacg attattatga atcaagggag
     1141 tcacaacatt gtcattatca accacataat gcttaatttt tccactaaca gctaatttac
     1201 gactttccaa accaacatct cagaaaccat tcttagcatc ccaaacagtt ctggaagtaa
     1261 tcactttagg agcactgaaa gttgtcactt tcctcaatac atggttataa aaatcaggat
     1321 atttttggta atcttcaacc gctgcaatct gagctaggta gcctccaaga gaatgacctg
     1381 tcatatacaa cttagtaata cttatatcct tggctaattc cccaacaacc ttgcggatgt
     1441 catccgcttg agctggctct gttatctcta cttttgactc ttcccttttg ttttcaagaa
     1501 cttcacttgc ttccggaagc gtttgaggag ctagtcttgg ctcctctcta agaggagttt
     1561 ctagttttgg agcatcattt tctgactctt tcaattcctc cttagaatct agcacaccta
     1621 ttaccacttc agttgttaca tcttgcttta cttcattggc tgaaattcca gctggagcta
     1681 gaaatcaaag ccgactacaa cagatacaac tccgatactt aattttttat gccaaagcgc
     1741 ataattcgtt gaccaatttt cattatttct tatctttctt ttcgtttatt tacaagcaga
     1801 ctcaagcgaa atctcattgt gctatatatg ataagactga gaaattcaga aagtcaattc
     1861 attctcatct ctccttatca tactagtctg cttggctagg aagctaatgc tagtatccta
     1921 gaatcttgtc tttcacaatg ctggctatca gatcagacac acctattctt ccgcttcttt
     1981 cagttataag agcaggaaga agctcatagt attcctctgt ttcttcttta atacggatag
     2041 gcagtcaatc ctgaaaagac agaggcactc ccccttttaa atcttttttc ttacaattca
     2101 gcaagaatcg ctttaagcaa gcctttaaaa tcacctttaa cacgttcagt cacttctaca
     2161 acttcttcgt gattgagttc ttcttggaaa ccagccgcaa agttagtgat acatgaaatt
     2221 cccagaactt tcaagccaga gtgggctgcc acgataactt caggaaccgt agacatacca
     2281 actgcatctg ctcccagtgt cttataggaa cgaatttctg ctggtgtttc ataagtcgga
     2341 ccagtaactc cgatatagac accttcatca agcttgatat taagtttttt agccacttca
     2401 tgggcagtag cacggtattc tggtgtgtag gccctagaca tatctgggaa acgtgggcca
     2461 aagtcatcca agttttcacc catcaatgga ttttgccccg tcatgttgat atggtctgag
     2521 atagccatca aggtaccagg accaaatccg ataccgccag ctgcattggt tacaataaca
     2581 ccttcacatc caagaacttt catcacacga actgggaaag tcaccacttc cagaggattc
     2641 ccttcataga aatggaaacg cccttgaaga gccaagacct tgcgacctgc cagttcacca
     2701 tataccaatt taccagcatg accgactact gttgaacggc cccagtttgg aatctcagca
     2761 tagtctacta caactggatt ttcgatttct tctgccaatt ctccaagtcc tgacccaagg
     2821 attagaccga actcaggggc tgcaattccc ttttctttca ggaaagtagc agtttcatgg
     2881 attttgttta aaaatgtcat tgtgtgtctc ctttattatt tttttagcat ttgaccaatt
     2941 ttgtcaaagg ttttagcatt acgaatagta atgtggcggt agaaaggcac ctcagcaagt
     3001 acttatgata ggcagtctta gaataggatt cttcagaaaa tttcccctag aaaatcccaa
     3061 gttttccaaa ataaagcact tcatctttca gctctaaact ttcaactgtc gcgatgactt
     3121 ggtccacatc caaaccctca gtgtaaaaga gaaaatcttt tcgtgccaaa tctctgctcc
     3181 accaagctgg tagattttca agttccgcct caaagtcctc tagactcagt aaagaaaagc
     3241 tctgaataaa tggataatgg actgcaaaga aagtctctag cttttcaacc aattgggctt
     3301 tggaatctat cgaagtaaag aaaatattgc cactgttgat gtagctctca accttttcca
     3361 gtcccaagtt tgtcaattct tgacgaagct ccgccatgac gaccttattc ttaccaccaa
     3421 cattgatacc tctcaccagc aaagcatagc gcgtcatctt ataccaattt atctaagaaa
     3481 ctttccccaa tcatagcagt ttccacacca aagttatcgg caacagtcgc tgaaatatct
     3541 gcaaaatgtc ctactggaat gagaccattt cctttaaagg cagggctata ggccaacaat
     3601 ggaatatatt cccgagtgtg atccgttcct gcatacgttg ggtcatttcc atggtccgca
     3661 gtaatcaaga gaaggtcatt ctctctcata gctgcgataa tttcaggtaa gcgttcatca
     3721 aactcatgca agcaatcacg gtaaccgtga gcattacgac gatggccgta aagggcatca
     3781 aagtcaacta ggtttgtgaa tgagaatcct ttttcaaact cagcaagtcc catagtcttc
     3841 aatagtgtat caattccatg actatttgac ttgttgtgac ccatgtcatg gttgatacca
     3901 gcaccgttaa agatatcgtt gattttaccc acagcataag tatcgatacc agcctcattc
     3961 aatttatcca aaacagttgg ggaaaatgga gatacagcca agtcacgacg gtttgccgta
     4021 cgagtgaagt tacctggttc acctacataa gggcgagcaa tgatgcgacc aagaagggca
     4081 ggacgctcaa gggtaatcga acgagcgtat tcacagatac ggtacaattc atccaaagga
     4141 ataatgtctt cgtgggcagc aatctgcaaa acagggtcag ctgaagtata gataatcaac
     4201 tctccagttt ccatctgacg tggtccaaaa tcatcgataa cagccgttcc tgaataaggt
     4261 ttgttggctt cacgaataac cttgcgtcct gagaattctt cgatttttgt caggatttct
     4321 tctgggaatc cgttccagaa agtatcgaaa ggctcagtaa tgttgagtcc catgatttcc
     4381 cagtgtccag tcatagtatc cttaccaaga gatacttcct ctaattttgt tgcatatcca
     4441 gttggattgc tttcagctgc tacagtctta agaggagttt cacgaggaat atttccaaga
     4501 cctattttag ccatgtttgg gacattcaaa ccaactgttt ttgaaatgtg tcccagtgtg
     4561 tcagaagctc catctggaac ccctgcattg acaaagttat tagcatctgg tgctgcaccg
     4621 attcctacag aatccagtac caccaaatga atacgattaa atttagacat cttatgcccc
     4681 cttctatttt cctttttttg aagttgaaat ctgaactcca tcccgtccag caacgatgac
     4741 cttatccacc atttggttga ataaaccatg ctccacaaca ccaacgacat ggtccaattc
     4801 ttgtccaaaa gcaattggat tttcaatgac atccaaggcg aggtcaatga taaaattctg
     4861 catatccgtc acaaaacgtt ggccgtcttt ttcacggaaa cttggtttgt agccagctcg
     4921 ttcaaaacga cgaaagacct gttctgcacc atactgaacc acttctactg gcaatttaaa
     4981 agcacctagt ttttcgacca gcttgctttc atccaccacc caaatgtatt cttttgatgg
     5041 tgtcgcaaca accttctcca tcagaagagc accaccacca cctttgattc cattaaactg
     5101 actatccact tcatctgcgc catcaactgt cacatcgaca aagtctactt ggtcaataga
     5161 tttgagtggg atattaaggc cttctgcctg tttagtggtc acactagaag tcgttacagc
     5221 tataatctgc aatccttctt ccttgatacg acgaccgatt tcttcgacaa aataataggc
     5281 agtcgagcct gttccaagtc caacgaccat tccatccttg acaaactcag cagccttgat
     5341 acctgccatt ttcttcagat tttccactca aacacctcca ttaaagagct acctctatta
     5401 taccatgtaa aggcttttat ttcatctaaa agtaccttta gaatactgct tatttatcct
     5461 tgaaattaaa tttttttaat aaaagcagaa ctctgacaaa tcactttaag tacggatgta
     5521 aaccaaatca actctaacaa aaatagattt acaagagtaa aaaaacgaac aaatttagtt
     5581 tcttagcgag aagaatacta aacgttcgtt ttttgtgaat taagaataat gatacaaatt
     5641 atcaatattt tttgtctaac tattttagac atatcttttc attactttag gaagacaatt
     5701 actaatctcc gttggcaaaa ccacatactg ttcttgagct agttcttggg ctatggctga
     5761 atgaagatgg gtcgctactg ccacacgttc gtaaagacta gcttgcttaa actggcctgc
     5821 aaatcctgca atcatcccag caagcgtatc tcccattccc ccagtcgcct gatagggacc
     5881 gccaacctgt aactggtaat aatctgattg gccagcttgc caaatacgag tagctgaacc
     5941 tttctccacc aaaattgttc cttgagggaa ggaagttagg gcactagccg ttgcatcttc
     6001 cttttgcttt tcaatcgtaa ttccagataa tttttcccat tctttttggt gaggagttag
     6061 gataagctgg cttgaggaaa atgacaaact tgtcctagca agaatggtca aggcacctcc
     6121 gtctacaatc aaaatctgat tttgtcttaa gccagcaaag acctgtttaa ctagatcttc
     6181 tccaaaagca tcgtctcgta aacccggccc cagcaagaca acttctgcct tctccaattg
     6241 ctcttttaac aactgctggt cttgaagaga aaaggccata gcctcaggta aatggctgtg
     6301 cagggctgga atattttccc tatctgttcc aacggtcacc aatcctgcac cgctttttac
     6361 agctgccaaa gcagccatga tgatggcacc accataagga taagttccac caagaaacag
     6421 cagacggcca tagtctcctt tatgactagt acgagaacgt tcaataataa ctttttctag
     6481 taaggcttga tcaatcactt tcatcgttct tcctcaacta tcctttatct gattgtttta
     6541 aaacaacttg atagactttc ttagtccact cttctaagtc ttctccagca tagtcaagat
     6601 aatgcaccct atcttgtatt ttagttggaa taatattttc aaattggctc ttattatgag
     6661 ttggaataat acaaatatac aactcactaa ataaattcaa catgtcctta atttttgcaa
     6721 catggtagcc atcaaaaata taaccagtaa ctttaatcaa atctgtatag ataaaatgaa
     6781 aactcactcc aggaataaac ttgtcttgta attctttctc tgaaggagct cgacctaata
     6841 aacgctccat cgctaatcga taaccagaac ttgtatttga ccaccctaac atgacataat
     6901 caaaataatc tatcggatcc gatgcagcat ttctactatc caaaaccaac tcttcagcat
     6961 ctcgcctaaa ggctttcaca gcagataaga gctgacctgt tttaaagata gaaatcgctg
     7021 catctatagt cgtagtatga ctacagtagt ctgaagtcac taacctctta tgtagatcat
     7081 aagtcgaggc tactctttta tctgtagggg taaatggtgg cagaaaggga tgctgacaga
     7141 tgtaatctaa aatttctttt tttaaacaag aatcagcaca ctcaatactt gtttgacgtt
     7201 tatgaagttt ttcgtaagct ataaatttag caattttttc taattcccac tcttgaatat
     7261 ttggataatc aattagtgct aggtagtata ttccatccca ttgtaaacta tattccctat
     7321 tataaatttt taaaatcatc taatcacctc actccattat acaacaaaaa ggaggcgcag
     7381 acctcctttt gtaatcttat atctaaaatt taatattcat ttctgccatt ttaaatatag
     7441 ctatagaaaa tacactctct tcagcgattt ttctcttatt ttctatccaa tgtccgaagt
     7501 gctgcttgat aagtttgctc catcagcata gtaatggtca tagggccgac acctccaggg
     7561 actggcgtaa tatagctagc aagtggggca actgcctcat aatccacatc cccacagagc
     7621 ttaccatttt catcacgatt catcccaacg tcaatgacta ccgcacctgg tttgacaaag
     7681 tcagcagtca caaacttggc acgaccgatt gcgaccacca gaatatctgc tttagcagcc
     7741 accttagcaa gattatgggt gcgtgagtgg gtcaaagtca ctgttgcatt cttggccaaa
     7801 agaagctgag ccatgggttt tccaacgata ttagaacgac cgatgacaac cgcattttta
     7861 ccttctaatt caatcccata ttcatgaaac atttccataa ttcctgcagg tgttgatgga
     7921 atcatgactg gatgtccaga ccaaaggcgt cccatattta gaggatggaa accatccaca
     7981 tccttttctg ggtcaatagc caatagaacc gcctcttcat caatgtgttt tggtaatggc
     8041 aactgaacca aaatcccatg ccaagctgga tcctgattgt atttagcaat caggtctaac
     8101 aattcctctt gagtaatggt ctctggaact cgcactactt cgctacggga accagccgca
     8161 agagctgacc tctccttgtt gcgaacgtag acttggctgg ctggattatc cccaaccaaa
     8221 atcactacca aaccaggcac tagagctgtt tcttccttta attttgcagt cttttcagcc
     8281 aactgcccct gcaatttggc cgctaaagct ttcccatcaa taatctgtgt catatcactt
     8341 ctcttttctt tcaaatatct tccattatac caaaaactgc tagtgccctc taacacttct
     8401 ttcctaggtt atcctatagt ttcaaactat aagaaaaagc tctggttgaa cttttcacta
     8461 atcttgtctt gaaattttaa aatagattat aaaaccttac tcaagaaatc tttagtccgt
     8521 tgttcttggg tttgttcaaa aatctgctca ggtgtcccat cttcaacaac cacaccgtct
     8581 gccataaaga taacacgatc tgccacctca cgggcaaatc ccatctcatg tgttacgata
     8641 accatagtca tccctgactt ggcaaggtct tgcataacag ccaatacctc acctaccatt
     8701 tcaggatcca aggctgaagt tggttcgtca aagagcaaaa catctggttc catagccaac
     8761 ccacgcgcga tggcaatccg ttgttgctgc ccacccgaca gactctgtgg ataagcgtct
     8821 gccttatctg gcaaaccaac tttttccaaa agctcttggg ctctcttctc agcaacttcc
     8881 ctgctttcac ctttagtctt gataggtgac aaggtaatat tttccatcac agtcatatta
     8941 ggaaagaggt taaattgttg gaaaaccatg cccatcttct cacgcatggc aaacaggtca
     9001 ttcttcttgt ccgtaatatc gactccctca aagataagct tccccttggt tgcttcctcc
     9061 aacaaattca tagagcgaag caaggtagat ttcccactcc ctgaaggacc gatgataacg
     9121 acaacttctc ctcttttaat ctcgaggttg atgcccttca atacttcatt ctttccaaaa
     9181 gatttatgta aattttcaat ttttatcaag gtttctgtca ttatttctta tctccttgtc
     9241 ccatatgttt ttcaaaagct ttcaaggcta ctgtcagaat agaggtcata atcaagtagt
     9301 aaaatgctgc aaataaaagt ggtgttaaag gtagataggt tgttgtagaa actgttgtag
     9361 ccccattcca caactccatg accccaatag ctgataagag ggagctgtcc ttgataatgg
     9421 tgataaattc gttccccaat gctggcaaga tatttttgac tgcttgtggc aaaatcacat
     9481 aacgcatcgc atttttaaga cgaatcccta gcgaataagc cgcctctagc tgaccttttg
     9541 gaaccgcatt gattccggca cgaacagtct ccgaaacata agcaccacta ttcatagaga
     9601 taatcaaaat ccctggaatc agacgcgaaa aatcaacacc taaaattcca atctgaatag
     9661 tcggagcatt gatatgcata agagcaaagg caatcataat ttgaaccatc atcggtgtcc
     9721 cacggaaaat ccaaacgtac aagttggcca accaaacaag cggtttaaac tttgaacgtt
     9781 gcccaaaagc caagacaaca cccaaaatag ttcccaaaaa gataacacag atagaaataa
     9841 gaatcgtcac aacagcccca tagttaaaat aaggtaaata cttaggtaaa aaagaaaaat
     9901 tcatagtcac actgctttct aaaatagaat actgtatgat tataacatgt tttgaattaa
     9961 aatttaaatt ttttatccaa tttatttaaa aatctttaaa ctagcagaat tagcgagaaa
    10021 tcttagtttt ttctagtcaa gttgccctcc tttatggtaa aatagtaacg ataagaaatg
    10081 aaggagaatc aaaatggaat cacatttggt tagaatcatc aaccgccttg aagcaatggc
    10141 aaacgatggc ggaaatttaa aacgtaattt tgaacgcgaa ggagttgttg ttgcagaagt
    10201 tgcgtacagc cacgacgaag aaaacggccc aatctttacc cttcgtgacg tagaagatcg
    10261 cgaaacgtat acgtttgata gcattgactt aatcgcaatg gaaatttacg aacttctcta
    10321 ctaatctaaa acaagttggg attgtccctg catgtctaag taaaatcctt tttgtctcac
    10381 aaataggatt tttttatagt ccaaattcac aaaaattttc attgtaacaa cttctcaaag
    10441 cttcaatctt tttacttgct ttacacccca atcctgttat aatgagagta tagaatttga
    10501 ctatttttga cctttaaaca agtcaggcta aagaaagaaa tgaggtagat gtatgctttg
    10561 tcaaaactgt aaaattaacg actcaacaat tcatctttac accaatctca atggaaaaca
    10621 aaaacaaatt gacctctgtc aaaactgcta taagattatc aaaacagatc ctaacaatag
    10681 cctcttcaaa ggtatgacgg atctgaacaa tcgtgacttc gatccctttg gtgatttctt
    10741 caatgatcta aacaatttca gaccttctag caatactcct cctattcccc caacccaatc
    10801 aggtggaggt tacggtggaa acggcggtta tggttcccaa aatcgtggat ctgctcaaac
    10861 tccgccacct agccaagaaa aaggcctgct ggaagaattt ggtattaatg taactgaaat
    10921 tgcccgtcgt ggagacattg accccgttat tgggcgcgac gatgagatta tccgtgtcat
    10981 cgagattctc aatcgtagaa ccaagaataa tcctgtcctt atcggtgaac ctggtgtcgg
    11041 aaaaacggcc gttgtcgaag gtctagctca gaaaattgtc gatggcgatg tgccacataa
    11101 actccaaggt aaacaagtca tccgtctgga tgtggttagc ttagttcaag gaacggggat
    11161 tcgaggacaa tttgaagaac gcatgcaaaa actcatggaa gaaattcgca aacgtgaaga
    11221 catcatcctc tttatcgatg aaatccatga aattgttggt gctggttctg cgagtgatgg
    11281 taatatggac gcaggaaata tcctcaagcc agcccttgct cgtggagaac tgcaactagt
    11341 cggtgctact accctcaatg aataccgtat cattgaaaag gatgctgccc tcgagcgtcg
    11401 tatgcagcct gttaaagtcg atgaaccaac ggtggatgaa acaatcacta ttctcaaagg
    11461 gattcaaaag aaatacgaag attaccacca cgttcaatat accgatgctg cgattgaagc
    11521 agctgcaact ctttccaatc gctacatcca agatcgcttc ttgcctgaca aggccattga
    11581 cctcctagat gaagctggtt ctaagatgaa cttgaccttg aattttgtgg atcctaaagt
    11641 aattgatcag cgcttgattg aggctgaaaa tctcaagtct caagctacac gagaagaaga
    11701 ttttgagaag gcggcctact tccgcgacca gattgccaag tataaggaaa tgcaaaagaa
    11761 aaagatcaca gaccaggata ctcctatcat cagcgagaaa actattgagc acattatcga
    11821 gcagaaaacc aatatccctg ttggtgattt gaaagagaaa gaacaatctc aactcatcca
    11881 tctagccgaa gatctcaagt ctcatgttat tggccaagat gatgcagtcg ataagattgc
    11941 caaggctatt cgccgtaatc gtgtcggact tggtacccct aaccgcccaa tcggaagctt
    12001 cctcttcgtt ggaccaactg gtgtcggtaa gacagaactt tccaaacaac tggctatcga
    12061 actttttggt tctgctgata gtatgattcg ctttgatatg agtgaataca tggaaaaaca
    12121 tagtgtggct aagttggtcg gcgctcctcc aggttatgtt ggctatgatg aggctggtca
    12181 attaactgaa aaagttcgcc acaatccgta ttctctcatc cttctcgatg aagtggaaaa
    12241 agctcaccca gatgttatgc acatgtttct tcaagtcttg gacgatggtc gtttgacaga
    12301 cgggcaagga cgcaccgtta gcttcaagga tgccatcatt atcatgacct caaatgcagg
    12361 tacaggaaag accgaagcta gcgttggatt tggtgctgct agagaaggac gtaccaattc
    12421 tgtcctcggt gaactcggta acttctttag cccagagttt atgaaccgtt ttgatggcat
    12481 tatcgaattt aaggctctca gcaaggataa cctccttcag attgtcgagc tcatgctagc
    12541 agatgttaac aagcgcctct ctagcaacaa cattcgtttg gatgtaactg acaaggtcaa
    12601 ggaaaagttg gttgacctag gttatgatcc aaaaatggga gcacgcccac ttcgtcggac
    12661 tattcaagac tatattgagg acacaatcac tgactactac cttgaaaatc caagcgaaaa
    12721 agatctcaaa gcagttatga ctagcaaggg aaacattcag attaaatctg ccaaaaaagc
    12781 tgaagttaaa agttctgaaa aagaaaaata aatcctatag aaaaggagta gaaaatgaaa
    12841 tttttctgct tcttttttta ctaaaataac tgtaatttct tgacagcttg ccctttgtcc
    12901 attatgat
//
LOCUS       DAVLBE010000049        12776 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.049, whole genome shotgun sequence.
ACCESSION   DAVLBE010000049 DAVLBE010000000
VERSION     DAVLBE010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12776)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12776)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12776
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.049"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(403..2130)
                     /gene="ezrA"
                     /locus_tag="VXB91_001580"
     CDS             complement(403..2130)
                     /gene="ezrA"
                     /locus_tag="VXB91_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HEV0470998.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAEGYNHSF
                     RFLKASHQIDQIESQITLIDEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLESGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPTQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(2212..4158)
                     /gene="gyrB"
                     /locus_tag="VXB91_001581"
     CDS             complement(2212..4158)
                     /gene="gyrB"
                     /locus_tag="VXB91_001581"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HEV0470999.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVHVHKNGKIHYQEYRRGHVVAD
                     LEVVGDTDRTGTTVHFTPDPEIFTETTIFDFDKLNKRIQELAFLNRGLQISITDKRQG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(4173..4736)
                     /locus_tag="VXB91_001582"
     CDS             complement(4173..4736)
                     /locus_tag="VXB91_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV0471000.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQA
                     LKVSTPFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEDILNQGGRHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(4821..5375)
                     /locus_tag="VXB91_001583"
     CDS             complement(4821..5375)
                     /locus_tag="VXB91_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HEV0471001.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGDLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYRDVFGKNQ"
     gene            complement(5386..6609)
                     /locus_tag="VXB91_001584"
     CDS             complement(5386..6609)
                     /locus_tag="VXB91_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEV0471002.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVPLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(6646..9096)
                     /locus_tag="VXB91_001585"
     CDS             complement(6646..9096)
                     /locus_tag="VXB91_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HEV0471003.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLREKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKTAASLELRKLSQDFSKNISLLNLEVREEQESFAKEVGLLLKDEPFSLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SQSLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEGFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSGRTLLSSL
                     LPESCQVLGVSATLEISQRVSLADLLGYPEAKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPSVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMVIIRLKQALGRSMRREYQRSLTLILDRRIVGKRYGKQIVASLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(9296..10225)
                     /locus_tag="VXB91_001586"
     CDS             complement(9296..10225)
                     /locus_tag="VXB91_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEV0471004.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELIVAVNALMHQDMMDRIKPFLDFLEEIKTDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARSLIQEGNFSH
                     DQAFLLDEEVRKLHPKNRFLDTGFYDYDPDMVK"
     gene            10365..10652
                     /locus_tag="VXB91_001587"
     CDS             10365..10652
                     /locus_tag="VXB91_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HEV0471005.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(10686..12020)
                     /gene="ciaH"
                     /locus_tag="VXB91_001588"
     CDS             complement(10686..12020)
                     /gene="ciaH"
                     /locus_tag="VXB91_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HEV0471006.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(12010..12684)
                     /gene="ciaR"
                     /locus_tag="VXB91_001589"
     CDS             complement(12010..12684)
                     /gene="ciaR"
                     /locus_tag="VXB91_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HEV0471007.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFVDVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
BASE COUNT         3883 a         2730 c         2272 g         3891 t
ORIGIN      
        1 actaaagttg tacaagaaaa gtgcaaataa gaaatctcca gattaggaac tatccgtgag
       61 ttctctagtc tggagatttt tcaatagact tcgttattgg acggttacca agttactcaa
      121 agtacagatt tgaagctgca gataagactg acgaaatcac tttaatacta aatgaaaatc
      181 aaaaagcaaa ctaagaagct agcctcaggc tgtacttgag tacggtaagg cgacgctgac
      241 gtgatttgaa gagattttcg aagagtataa aacactgttt tgaggtggtg gataaatcgg
      301 ctgggtaaaa actcaatctc aggagaaaat gaagtaaatc tccccacaac tatagaaaaa
      361 gatttgattc tgctcctcac acaataaaat ctttttcttt tattaaaaac gaatcgtttc
      421 acgtgttttc tcatatgagg taacaaagcg attggttaca ccaggctctg ccacttccaa
      481 tgcttgagaa atcttgtcaa atgaagcgtg ataatcaaat tctttttcaa aaatatctaa
      541 agcttcgtta aatgcttctt gaatgcgttc atcaaatgag cgatagcggt tagaatattg
      601 caagagttgc tctgtcaaag ttgcatattg tacaatatta taagtttccg tttctaaagc
      661 ttccatatca ttcgttgcaa tttcaagaac tcgggtaaca gattcaatgt taatcatttt
      721 ttgttctaac tcaaccatta aatcctcggt attattgctt gccgtaaaga ataacttcaa
      781 gaaagtttgt ggaatacctg gcagattgcg tttttccatg tatcgcttga tagtatggag
      841 acgattgaca taaacattgg ccttttgacg tgcattaata tcatctttct caatttgtgt
      901 caggcgctca ctaactgaaa tttgctcatc ttcaatatct tttagttgag tttgtaaatc
      961 ctcaagattt tcttcaagaa ctgaataagc ttgggttggt tcttcttgat ttgaagttac
     1021 ctcaacaata gctgcctcaa aactctctaa ttctgtctga atacgacgaa catggcttgc
     1081 agctgtctca ggaagtaaat aggtcttgtt caaacgtgca atatcttctc ccaataaagt
     1141 attattctct ttcatatgtt gaaggtaagt tggaagagtt gcaagtagat tttccactac
     1201 tttctgagca gcaatttctc gagtaaaaat atcatacaag gcattgattt cctcttgtgc
     1261 ctgtccattc tcatattcgg cattatccaa ttccaactga cgaatattct cttggttttt
     1321 cttgaatgct tcataaagca agtggaaacg cgcttcaata tccgtttcaa caaaatgata
     1381 attagcatca attagtttac gataaccgga ttccaaatcc tgtaattgat ctggcaattc
     1441 tgtagaaagc gtcgtaacca aggctggaac acgatccaca atatgactta aggccaaaat
     1501 gtgattttct gtattatcca aaatcactgc ggcttccaca gggtcacccg atgaattcaa
     1561 ggttacaaat tgtgaaaatt cagattggat attttctaat tgtttttcaa tttcatccaa
     1621 ggcttgacca tactgttctg aattttcagc aactctatgc tgaagttcct caaataaatc
     1681 caaagcatga agaacacgac cactattttt agattcttgc ttctctaagt ctgccaaagc
     1741 attgcgaatt gccgcaatat cttcgtcaat caaagtaatt tgactctcaa tttggtcaat
     1801 ttgatgactg gccttgagaa aacgaaatga atggttatag ccttctgctt caaagagatt
     1861 attttcaata tcggcaaaag agttgagaga taaatcgacc catttttgat tccattcacg
     1921 gaaagccact tgactttgtc caatcaagtg catatttttt acagcttcta cttcatcatt
     1981 tactggaaga ttgtatagtt cttcttttct ttcttctagc gcctctaatc tcccctcgtt
     2041 tcgcttacgt agaaagattg ccactacata agccagaact aaaatgactg caattgcaac
     2101 cattaaataa attagttgtc cattagacat atcaaactcc ttttttactt gaaacaatcg
     2161 taacgattat atcatatttt ttagaccaag ggaactactt ctccctattt tttagacatc
     2221 aagtgtacta tagacagcat tttcttcgat aaactcacga cgaggctcta ctcgatcccc
     2281 catcaacata tcaaagattt tatctgcttc tgcagcatca tctacagaaa ctctagccat
     2341 caagcgatgt tcgggatcca tggttgtttc ccacagctga tgatcgtcca tttcacctag
     2401 ccccttataa cgctgaatag tcggtttggt acgaccttca ctataacggg ctaaagcttc
     2461 ttggagtttg atttcttgat ctgcacccgg ctggatatat tctttaatct cgcttccaac
     2521 cttgacacca tagattggtg gttgggcaat ataaacataa ccagcttcta ggattggttt
     2581 catataacga taaatcaagg ttaaaagaag ggtacgaatg tgggctccat cgacatcggc
     2641 atcggtcatc aaaacgagtt tttggtaacg ggctttcgaa acatcaaatt ctgcgccaaa
     2701 tcctgttccc atggctgtga aaagactacg aatttcttcg ttagctagaa tcttatccat
     2761 acttgctttt tcaacgttca aaatcttacc gcgaattgga aggatagcct gaaactcacg
     2821 gttacgacca gatttggctg atccaccagc tgagtctcct tcgacgatga agagttctgt
     2881 ttcagcaggg ttattagaag aacagtctgc tagtttccct ggaaggttgg aaatttccaa
     2941 accagatttt ttacgtgtga cttcacgcgc acgcttggca gccacacgag ccttggcagc
     3001 taaaatccct ttttccacga tacgtttggc aatctgtgga ttttccatga ggaaatcgga
     3061 gaaggcttca ctgaagaggc gattggtaat cttgaccact tcgctatttc ccaatttggt
     3121 cttggtttgt ccttcaaact gtggatttgg gtgtttaact gagataactg cagttaatcc
     3181 ttcgcgaaca tcttcccctg ttaaattatc ttcattgtct ttcagtaact tattcttacg
     3241 agcataatca ttgataacac gagtcagtgc cgtacggaaa ccttgttcat gcgttccacc
     3301 ttcatgggta tgaatattat tggcgaaact catgacattt tcatggtaac ctgttgtgta
     3361 ctgcatggct acctcaactg tgatatcatc catctcaccg tctgtataga ttggtgtatc
     3421 aaagattaca tccttgttct cgttgatata ttcaacgtaa ctagcaatcc caccttcata
     3481 atgataatgc ttggtttgtt ccaaaccttg gcgcttatct gtaattgaaa tttgaagacc
     3541 gcgatttaga aaggccaact cttgaatccg tttatttaat ttatcaaaat caaagattgt
     3601 tgtttcagtg aaaatttctg ggtccggtgt gaagtgaacc gttgttccag ttctatctgt
     3661 atccccaacc acctcaaggt ctgcaacaac atgaccacga cggtattctt ggtaatgaat
     3721 cttaccgttt ttatggacat gaacgtctaa ttgagtggaa agggcattaa ctactgacga
     3781 ccccaccccg tgaagaccac ctgaaacctt gtatccacca ccgccgaact ttcctccagc
     3841 atgaaggact gtaaagacgg tctcaacagc aggacggcct gttttttcct gaatatcgac
     3901 tgggatacca cgcccatcat ccacaacagt aatcgaatca tctggctcaa taaaaacttg
     3961 aatatggctg gcaaatcctg ccaaggcctc gtcaattgag ttatcaacaa tttcccagac
     4021 tagatggtga agaccttctt ttgaggttga tccaatgtac atccctggac gcatacgaac
     4081 agcctctaag ccctctaaaa cttgaatttg actggcatca taatcctgtg cctgcagatt
     4141 tttgatttct tctgtcatct tattcctttt tcttatatgt ctaatacttg tcttaaattc
     4201 acgatactgg taaacaagtg ggtatcaagt cctgcagctt gacctgcttc gatatcaatc
     4261 ggccgatcac caatgacaag accagagcta atctgatact tttctcttaa ataaagcatg
     4321 gattcgggat ttggctttct cttaaagcct gagctagaag tcaccacttc tgtaaaataa
     4381 gctgctatag aggttttttc taaaatttcc aaaacctgat catttcgatg agagaccaaa
     4441 aaatgacggc caccttgatt taaaatgtct tccaataggt cagaaactcc ttcaaataaa
     4501 atcgggtgtt caagctctct ggcttcattt tccttgtact tttctaaaaa attctctaaa
     4561 ttgggagcga atgtctcaat cgcaaaagga gtagaaacct ttaaagcttg atagacactg
     4621 tcatggtctt gtgtgatacc atacagtgcc aatgtttcaa caaatgcagc tgttgaagtt
     4681 tcataattat ccagtaaagt tccacctaaa tcccagatgt aatcgtgata tttcataccc
     4741 ttcattatag cattttttta tgaaaaaagc gatgatttcc ctgagttttc cacataaaaa
     4801 acgagagaat aactcccgtt ttactgattt ttaccaaaga catctcgata gagcattcct
     4861 gttcgtaaac tctctgcgtc ccctcctagt tgctccacca actcgtaggc aaaggcaagg
     4921 gctgttgaag gaccccgact ggttgtcaac tgaccatcta ccactactgt ttccttgacg
     4981 tagtgaccat caaggatttg ctcttgaacg ccgtcataac aagtgtatcg cttatttttc
     5041 aatatctctg cttgattgag ggcaattggt gccgcacaaa tggctgctag tttcttccct
     5101 tcttgctcga agctttgcaa ttcttgaatc aaggtctgat tatcacgtaa atgtgcagaa
     5161 ccaggcatac ctccaggaag aacaatcata tcatagtctg ataaatctcc atcaaagaca
     5221 tgatctgctc ttacttggat tgcatgcgaa cccgttactt gctcttcaaa accaaccata
     5281 tcacatgtga tattggctcg acgcaagaca tctacaactg tcaaggcttc aatttcttca
     5341 aagccctgag ctaacataac tgctactttt accatgattt tctccttatt taatttgttt
     5401 taatacaacc tttttccgtt tgaatgggac ttttccgctc ttttcttcag ctaaattagt
     5461 ctggtaactc atcgataaaa gcaaaccaac accaatcaaa ttactgataa tagctgatcc
     5521 cccttgcgaa atgaaaggca agggaatccc cgtcaaagga agtagtccag tcacagcacc
     5581 gatattctca aagatgtgga agagcaacat cataatcaaa cctgtggaaa tataagtgta
     5641 gaactggtta tttgatttaa gagtaatctt caacatacgg taaatcaaca tgagatagag
     5701 ggcaataacc aggacagagc caataaagcc aaaatcttct gcaataaccg taaaaatcat
     5761 atctgactct cgaactggga taagcagatt cgaagcatta aatccctgac caaataagcc
     5821 accactccca atggcaatct gcccttgagc ctgctggtaa gtcgttgttt gggcaaactc
     5881 aaagggattg agccaagcca aaatccgatt aatttggtag gtcggcattc caatctggtg
     5941 aagaaaagct cgtccgtcct tgctaataaa gatagctaag aaaccagcaa ctcctgttac
     6001 agcagtcaca aatactggga taataatttt ccaagaaacc cctgataata aaacgattcc
     6061 tgagaaaatg gctacaaaaa ccaaagccgt ccccaagtca ctttgaagtg ctaaaagaac
     6121 taggactgga atggtaaaga gaatcatcca gaaaattaac aaaaagtcca gcggaaccgt
     6181 gcgtctccat tccttatgtt tctttgtaaa ttggacaatg acacgagcca acatgaggat
     6241 ataggatatc ttcataaatt ctgacggttg aaatagggta attccattta ttgataccca
     6301 gtttttggca cccgttgatg caactaagct tggattataa aatacaatcg gcaagatcat
     6361 aagtcccaag cctaaaatat atagaaaggg ggtcaccttc caaagaaatt ctgtattaaa
     6421 gagcatgacc acaaaaccaa tcacaagccc caaggcaatc caggcgacct gctgccctaa
     6481 aatgggcaga atattattgg gataatcatg actaacggct atatagatag ccaccacacc
     6541 gatgaccagt agaaaaaata ctggcaagag caaactataa tcgactctag agtcgagaga
     6601 acgtttcata tgtactaacc ttatactttc atacaatact atttatcaaa gttcattaaa
     6661 aaatctatca atagcctcgt caacttcgga tcgagagatg gttttaacag tcgcttcttc
     6721 tgctagagat gctactattt gtttgccgta tcgttttccg acgattctcc tatccaaaat
     6781 aagagttaag gaacgttggt attcacgtct catacttctt cccaaagcct gttttaaacg
     6841 aataatgacc attggcaatt gataatcata aaaggcattt ttcccttctt gattcagttc
     6901 ttgattaatc tttttcgtca agggttcttg aggattttgg aaaggaagcc tcggtacaac
     6961 ttgaatcaca gaaggatggc ttgaaaaatc aactccctcc cagaaacttg ctgcaccaag
     7021 caagatttgt tgttcacctt tttcaaagcg tttctttagc tgatgaacat ccccattttt
     7081 atactgggcc aagtggctaa ctgtaagtaa atccgatact gctagaagca tgtctttagc
     7141 ggtaaagaga accaaaatcg gttgctggaa agcttgaatt tccactagta aagcagctac
     7201 ctctctggca tagacttcta aggaggtttc tgttaccaga gggaaatctt tgaccataac
     7261 cacttcttgt tcctgttttc cccgagattc aatcttgaca aatttggctt caggatagcc
     7321 taaaaggtct gccaaagaaa ccctctgact aatctcaaga gtagccgata ctcccaagac
     7381 ttggcaactc tcaggaagta aagaggacag aagagtacgg cctgattttg tagaagaaat
     7441 ctgaattttc ttttgactcg tttcagttac ttcaagccag taatcacctt cagctgtaaa
     7501 atagcgaacc agctcatcaa agccttccac ttctaattct gaaaaatact gatggagatt
     7561 gtccagagaa tctaagatat ttttcctaga tttaccagac tgaaattgtt ctatcaagta
     7621 gagacactca aagcgaatac tttctagtat ccgttgttga accctgtttt cttctcctac
     7681 taaagcctta tcaattaaat cgataataga ttgtatatcg taggtctctt gaagcagatt
     7741 ttctagagct aacaaaatct tttggacttc atcaataatc agtaaacggt cactgacaaa
     7801 ttcaggatta tcttcaagtc tggtcacgag ataggcatga ttagtcacta aaagcttgca
     7861 agtctctgcc ctttcttgac tacgtttcca aaaatcttcc gtcacaaata agctctggga
     7921 tgataaattc ccatcatgac gaaggtctgc tagaaaatgt tggtaacggt agagttgccc
     7981 gatttcatcc aaatctcctg tctctgtctc agtaagccag accaagactt gcattttaaa
     8041 gcgtctaaat aagcgatttt catcattttc ctgcaaggaa tgataaaagg catccaactt
     8101 cagataattt tgtggtccct ttaagctatg aatatctgta tggaacactt ccttgagacg
     8161 tttaccttct tcttccatga tttgattttg aagaatcttt gtcggaacac taagaacaat
     8221 ttgtcgctct ttggattgag ataaagcggg taagagatag ccataggttt tcccaatccc
     8281 tgtcggcgct tgaatcagag agaaaggttc atctttcaat agcaagccaa cctctttagc
     8341 aaaactttct tgttcctccc tcacttcaag gttcaacaga gaaatatttt tagaaaagtc
     8401 ttgagatagt tttcgtagct ccagagaagc tgccgttttc ttaaaataca gaccttgaac
     8461 ttggaccaag tctggagaac tcaggataga ttggttgcga taagtttcct caataaccag
     8521 gtaagactca tataggagag cgtcagccat ttccagcaag cgttccaaga gacctttagg
     8581 aagctgggtc atcttttccc gtaaaaaaag aagtaattct gctgtagctt gggcatctga
     8641 aagggctgtg tgtgcgtgtt taagaggaat tcctaattct cgacacaaaa tcggcaagct
     8701 atatttttcc agttcaggga aaaagacctg ggccaattcg accgtatcaa cacgagggtt
     8761 tcttagctca tagccttcaa aaaataaatt ttccgccaag agattagcat caaactgaac
     8821 attatgggct acaaaaatcc catcctccac caagtcaaag atttttctgg caacttgcga
     8881 aaaatcaggt gcttgcgcca gacgttggtc tgtcaatcct gtcagttctt tgatatgagc
     8941 atccaagggt tcatgtggat tgacatccgt cgtatagtga tcgacgattt ctccatcctc
     9001 aatcacgaca attcccactt ggataatttt agccttacta cctgtgctag ttgcctctaa
     9061 atccaccaca acatagcgat taccaatcgt tttcattata aaaaattata ccaaaaaaag
     9121 ggccatttgg cacctgcaaa cataggataa ttttcaaact caagaacact acttttctta
     9181 gaaatcccat cgaatagagc attctagcct gctgattttt ttaaaatagt gaagaaatac
     9241 gaaaaattga gagaagaaat gttttcatct tccttctctc aacgaatcat gtattttatt
     9301 taaccatgtc aggatcgtag tcataaaatc ctgtatcaag gaaacggttt ttagggtgaa
     9361 gtttacgaac ttcttcatcc agcaagaagg cttggtcatg gctaaagttg ccctcttgaa
     9421 tcaagctacg cgcttggata aagagttttg caatctcaac aaagttctga ccaggagtgt
     9481 agagcccttc tagtttccag cgagtaaagc catgctccac caattctgtt aatttgatca
     9541 tcaaatcaag gtcattgttg gcaaagatat gggtcccatg attatcttca aaaatggaat
     9601 agtggctctc tggatcactt ggctcagcca agaagaggtc acgtttatgc gtcttttcat
     9661 catcgatatg tgtaaagtta tagtagtttt gcaagagtgg acgtttagaa tgatggatga
     9721 cgctagcacc gtaaaccaaa acttcagcag gaatttccaa aatctctggc attttgaaaa
     9781 gttcagctga tggaatttca cgcgccaaaa cagcctcaga tgcgccagcc ttttgtcccc
     9841 agaagttaat ctgacgactg ctagttacca tggttgaagc atcgtagatg gtcttaaatg
     9901 aataaccatc gcggttaact acgtaaaaga cgcctgcatc cccaatcgta atatagtctg
     9961 tcttgatttc ttccaagaag tctaagaaag gcttgatacg gtccatcata tcttggtgca
    10021 tgagagcatt gaccgcaacg atcaattcct taccagcatc atgaaccaac ttagcgattt
    10081 cacgtaattg gtcataacta aaggtcgttg gcagacgaag gccaaaatct ttctcaccga
    10141 catagatacg gtctacgcca gcttcgagta gttgttcaac ttgttcaata ctttcagcag
    10201 ttgctgtaat gacaatcttt tccataagaa aaattatacc acatttctcc aaaatcagcc
    10261 atgctttgaa aatgaaaagg gactttattc tttttgtaac ctttctgtaa taattctctg
    10321 ccgaaaaaat gataaaatag gtatgtactg ttaaggagag aatcatgccc gtaagaaaat
    10381 tacaatccta tgaggtagac tatcaagaag aattaaacca gcagcttcct cattaccaag
    10441 cttatacacc tgaagcgcaa tctgatgcca atctcaagga aatcctattt tttattaata
    10501 tcgctgtttt ttgtatctgt attgctatct ttagttttat ctttttagca ttaaaattat
    10561 caactgctct tgcctttgcc gcagcaatcg gattcagctt acttgtttta aaagttcaac
    10621 ggtctattat caaacgaaaa cgtagaagat aaatccaaaa tatcgcccca attggagcga
    10681 tatttttatt ttttcttttt agatggtgtc tgaatggcaa tcttcacttc aaagattgtt
    10741 cccttgggtt tattatcttt gacagtaaca gttcctttta gagcatctac aatttgcttg
    10801 gctagggata atcctaaacc aaaaccacct ttttgccggg ttctagcttt gtctactcga
    10861 taaaaacggt caaaaatttt ctttttatct tctgtcgaaa taccgattcc attatcagaa
    10921 acaagtaaat aaagattgcg atcggtcgcc gagataagaa aatcaatttc accatcctcc
    10981 tcagtatact tgacggcatt atcgaaaaga atggtcatca gttgtttcag aagaagctga
    11041 tctgtgacaa ttgttcgatg gatacgattt tcaaaacgga agacacgatt attttccgaa
    11101 gcaatcatct catagtttgt gaaagttgta ttaaaaaagc tagttggaac ttctgcaagc
    11161 tccggcttaa tcccatcatc tctccgagct aagttcagca agcttgtcgt taaaaaacgc
    11221 atatttcgga cttcttccaa actcgatgca atgctttcgc tcacatccat aatggtagct
    11281 tctggcttac gaaaaagggt ctctaagcga ttttgcaaaa ctgcgagtgg agttcgtaac
    11341 tcatgactgg cattttccac aaaagactgt tgcttctgca tactctcaag caggggccta
    11401 acactgaccc tagctagata gagactggca agtaaagaca aaatccagaa actagccatc
    11461 acgaccacaa tcaattgctc atgcttttga ctagcctgct ccaactgact ggtattaatc
    11521 aagacagcag catacttgat attggttgaa accgaactaa tattggtctc catcaaaatc
    11581 acacgataga tttcttcctg cccatagcta ttaaaaacct gaatctggta gatatgtcct
    11641 agttctttct tttctaactt aatcttatcc aagcccaaaa atcgatttcc agaaagaagt
    11701 tgagtaaagt ctttatcaaa gagaatgact tccgtattgg aactgacatt aggttttatt
    11761 tctactttac tagcgtccgc cctagcattt tctaaatctt taatctcttc tgttgcccta
    11821 tttatagcca gctgaataac tgcttgagga ttttcactca gtccatgaag cttatcgtcc
    11881 accgaagtat aaagactcga atgcatgact tgtaaaataa tcagagtcat tgtagaaaaa
    11941 atcagggtga agacaccgaa gttgcggata aaataactaa agtcatccgc ataccatgtt
    12001 tttttaagtt tactgaacat cttttaaaag atacccaaca ctacgcaagg tttgcaaatt
    12061 ctctgcaaaa gtggttccct ttaatttctt acggactttt gaaacataga cttcgacaac
    12121 cgaaatcgtt gtatcactat caaatcccca tagacggtca aaaatctgcg tcttaggcaa
    12181 aatcacattt tgattttgaa ggaaataaac tagtaaatcg aactctttcc ccagcaattc
    12241 gacaggagta tcttcaactt taacggtatt ggttgataaa ttaaccacga tattcccata
    12301 agtcaaggtg ttttcattaa acttccctga acgtttgaga agggcctgaa ttcgcatttt
    12361 aagttcttct aggtagaaag gtttggtcag ataatcatcc gctcccagtt caaatccatg
    12421 tcccttgtca tccaaacttt ccttggcagt cataatcaga actggtgtcg taattccctt
    12481 ttcacgcaat tcttttaaga cttggaaacc atttttttct ggcaacatca aatccagcaa
    12541 aatcaagtca tagacaccac tctcagcttc gtagagacct tcttctccat caaatacctg
    12601 cataacatcc acaaaatcgt ctaaaaagtc aaatactgaa tttgacagac ctaggtcatc
    12661 ctcaaccaat aagattttta tcatgagaaa ctcctcctta ttaaaactat tataccaaat
    12721 ttgccttaaa aaaaactcaa ctctctgcat tttacatgag atagctgagt tttctt
//
LOCUS       DAVLBE010000050        12713 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.050, whole genome shotgun sequence.
ACCESSION   DAVLBE010000050 DAVLBE010000000
VERSION     DAVLBE010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12713)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12713)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12713
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.050"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(175..372)
                     /gene="blpI"
                     /locus_tag="VXB91_001590"
     CDS             complement(175..372)
                     /gene="blpI"
                     /locus_tag="VXB91_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpI"
                     /protein_id="HEV0471008.1"
                     /translation="MNTKMMEQFSVMDNEELEIVSGGRGNLGSAIGGCIGAVLLAAAT
                     GPITGGAATLICVGSGIMSSL"
     gene            654..1241
                     /locus_tag="VXB91_001591"
     CDS             654..1241
                     /locus_tag="VXB91_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C39"
                     /protein_id="HEV0471009.1"
                     /translation="MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKT
                     NKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDVPYPFIVHVNKEGKLQHYYVVYQ
                     TKKDYLIIGDPDPSVKITKMSKERFFYEWTGVAIFLATKPSYQPHKDKKNGLLSKLPS
                     SDFQTKISHCLHCSLKLIGHYYQYRWFLLSPRNLG"
     gene            1168..2811
                     /locus_tag="VXB91_001592"
     CDS             1168..2811
                     /locus_tag="VXB91_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEV0471010.1"
                     /translation="MVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVI
                     TYILQQVMSFSRDYLLTVLSQRLSIDVILSYIRHIFELPMSFFATRRTGEIISRFTDA
                     NSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLISIPIYMFIIFSFMKPFE
                     KMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYS
                     ILQTSLKQGTKLVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQT
                     KLQSAKVANNRLNEVYLVESEFQVQENPVHSHFLMGDIEFDDLSYKYGFGRDTLTDIN
                     LTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRHINY
                     LPQQAYIFNGSILENLTLGGNHMISQEDILRACELAEIRQDIERMPMGYQTQLSDGAG
                     LSGGQKQRIALARALLTKAPVLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAHRL
                     SIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK"
     gene            2822..4183
                     /locus_tag="VXB91_001593"
     CDS             2822..4183
                     /locus_tag="VXB91_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HEV0471011.1"
                     /translation="MNPNLFRSVEFYQRRYHNYATVFIIPLSLLFTFILIFSLVATKE
                     ITVTSQGEIAPTSVIASIQSTSDNPILANHLVANQVVEKGDLLIKYSETMEESQKTAL
                     ATQLQRLEKQKEGLGILKQSLEKATDLFSGEDEFGYHNTFMNFTKQSHDIELGITKTN
                     TEVSNQANLSNSSSSAIEQEITKVQQQIGEYQELRDAIINNRARLPTGNPHQSILNRY
                     LVASQGQTQGTAEEPFLSQINQSIAGLESSIASLKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLENNTLTSPSKGIVHLNSEFEGKNRI
                     PTGTEIAQIFPVITDTREVLITYYVSSDYLPLLDKGQTVRLKLEKIGNHGTTIIGQLQ
                     TIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTTKKTYFDYFKDKILT
                     HSD"
     gene            4240..4368
                     /gene="blpC"
                     /locus_tag="VXB91_001594"
     CDS             4240..4368
                     /gene="blpC"
                     /locus_tag="VXB91_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HEV0471012.1"
                     /translation="MDKKQNLTSFQELTTTELNQITGGGLWEDLLYNINRYAHYIT"
     gene            complement(4439..5779)
                     /locus_tag="VXB91_001595"
     CDS             complement(4439..5779)
                     /locus_tag="VXB91_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV0471013.1"
                     /translation="MNIAWILLYTLVTNGLEIVIFFKVDGIDLTFERIFKAFLFKILL
                     AFVFVMISYIVGNVYLSYFMEPLYGIGLSFLLLRGLPKKLLFFYGLFPMILVNLFYRG
                     VSYFVLPFLGQGQVYDGYSFTGLCIIIFNFFISLAFLKWLDYDFTSLRKEILDKAFQK
                     SLTQINWIMGGYYLVMESLSFFEYEQSIQSKTVRHLILVFYLLFFMGVIKKLDTYLKE
                     KLYERLEQEQALRYRDMERYSRHIEELYKEVRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EVYGSVLKDSSQKLQNNKYDLGRLVNIRDKALKSLLAGKFLKARDKNIVFNVEVPEEI
                     QVEGMSLLDFLTIVSILCDNAIEASVEASQPHVSIAFLKNGAQETFIIENSIKEEGID
                     ISEIFSFGASSKGEERGVGLYTVMKIVESHPNTSLNTTCQNQVFRQVLTVIHTE"
     gene            complement(5793..6530)
                     /locus_tag="VXB91_001596"
     CDS             complement(5793..6530)
                     /locus_tag="VXB91_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0471014.1"
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKAHHIIPSSFEVFGKPDQLL
                     AEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRDPYALIVFVTTHSEFMPLSFRYQ
                     VSALDYIDKALSAEEFESRIETALLYANSQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
                     LETSPRAHRVILYTKTDRLEFTASLEEVFKQEPRLLQCHRSFLINPANVVHLDKKEKL
                     LFFPNGGSCLIARYKVREVSEAINKLH"
     gene            complement(6535..6873)
                     /locus_tag="VXB91_001597"
     CDS             complement(6535..6873)
                     /locus_tag="VXB91_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0471015.1"
                     /translation="MKYMIIQTQKTVYKVNIDDIYYIQTHPTKAHTVQIVTEEASFNM
                     LQNLSNLENQCGETLMRCHRNCLVNLDKLKSIDFQERILFLGEEGQYAVKYARRRYRE
                     IRQKWLKEGE"
     gene            7149..7478
                     /locus_tag="VXB91_001598"
     CDS             7149..7478
                     /locus_tag="VXB91_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HEV0471016.1"
                     /translation="MTDTDPIKRAHTLITDLNKAYQACKQASADDVRFQEQLNSILGF
                     LAKAETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLIL
                     NENQRAN"
     gene            complement(7646..8695)
                     /locus_tag="VXB91_001599"
     CDS             complement(7646..8695)
                     /locus_tag="VXB91_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0471017.1"
                     /translation="MKDLFLKRKQAFRKECLGYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEEIKLHLKRQTG
                     ISLVFWLFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFRQKASKFFTETG
                     LDWDYVISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVSGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSVLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHDFD
                     YQYLTQLFPLDKGQKEKGLQEVVRGLTSFVLLVELVVGLITFQEKLALLALLGAGLVL
                     LVLYLPYQVKRQMQD"
     gene            complement(8692..9423)
                     /locus_tag="VXB91_001600"
     CDS             complement(8692..9423)
                     /locus_tag="VXB91_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0471018.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMFRLEQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            9491..9901
                     /locus_tag="VXB91_001601"
     CDS             9491..9901
                     /locus_tag="VXB91_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEV0471019.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMDATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            9911..10198
                     /locus_tag="VXB91_001602"
     CDS             9911..10198
                     /locus_tag="VXB91_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0471020.1"
                     /translation="MKLSNLLLFAGAAAGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIIDQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
     gene            10360..10644
                     /locus_tag="VXB91_001603"
     CDS             10360..10644
                     /locus_tag="VXB91_001603"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0471021.1"
                     /translation="MHHNLGNSYSIKIKKQTRKLGTDCSKHRFKVVDRTDEVSSKHCF
                     EVVDTTDEVSSKHCFEVVDRTDEVSNHTHDKPTLTWFEEIFEEYHSPFHN"
     gene            complement(10956..12092)
                     /gene="dnaJ"
                     /locus_tag="VXB91_001604"
     CDS             complement(10956..12092)
                     /gene="dnaJ"
                     /locus_tag="VXB91_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HEV0471022.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGAGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGRGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFAAAGDLKVNPKKKGFFDHIKDAFDGE"
BASE COUNT         4125 a         2723 c         2223 g         3642 t
ORIGIN      
        1 ccaatccatc aactaagtaa agcatcaacg attacataaa cgattgataa tataattaaa
       61 attttgctaa ctatcttatt ctcatgattc ttagataact ttgatatttt gtaagtaagt
      121 aaataagaca gtaaattaat agcgataata atactatatt taagaatcat aatcttacaa
      181 agaggacata attcctgaac ctacacaaat aagtgttgct gctcccccag ttatcggacc
      241 agtcgcagca gctaatagta ctgctccaat acaaccaccg attgcagatc ctaaattgcc
      301 tcttcctcca ctaactattt cgagttcttc attatccata acagaaaatt gttccatcat
      361 ttttgtattc atgacaaata ctcctttttt ctttttttat ttttgtcttg ttgtaacttt
      421 gataagttta gtatatcatc gttttttaaa atttttcatc cagatcttga attgtcatcg
      481 aaacgtcttg aattaggttt tttatttcaa gccacctcta aatgtttaaa aaaaataatt
      541 tctaatcact tttttaccat tcaggaagtt ttaatgacta ttcaagattt cataaaatat
      601 gaacttagtt ttatgacata atagacctat ccactatatg aaaggaattg ccaatgactt
      661 cttataaacg tacatttgtt cctcaaatag atgcgagaga ctgtggtgtc gctgccttag
      721 cctcgattgc taaattctat ggttcagatt tttctctagc tcacttgaga gaacttgcaa
      781 agaccaataa agaagggacg actgctcttg gcattgtaaa agccgctgat gaaatgggct
      841 ttgaaacaag acctgttcaa gcagataaaa cgctctttga catgagtgat gtcccctatc
      901 catttatcgt tcacgttaac aaagaaggaa aactccaaca ttactatgtt gtctatcaaa
      961 caaagaaaga ctatctgatt attggtgatc ctgacccttc tgtaaaaatc actaaaatgt
     1021 caaaagaacg ctttttctat gaatggactg gagtagctat ttttctagct accaaaccca
     1081 gctatcaacc ccataaagat aaaaagaatg gtctactaag caagcttcct tcctctgatt
     1141 ttcaaacaaa aatctctcat tgcttacatt gttctctcaa gcttattggt cactattatc
     1201 aatataggtg gttcttacta tctccaagga atcttggatg aatacattcc aaatcagatg
     1261 aaatcaactt taggaatcat ctcagttggt ctggttatca cctatatcct ccaacaagtc
     1321 atgagcttct ccagagatta tctcctaacc gttctgagtc agagattaag tattgatgtg
     1381 attttatcct atattcgcca tatttttgaa cttcccatgt ctttctttgc gacacgtcgt
     1441 acaggagaaa tcatttcacg attcacagat gctaactcta ttatagatgc cttggcttct
     1501 accattcttt ctctttttct ggatgtttct attctgattc ttgtaggagg cgtcttactg
     1561 gcacaaaacc ctaatctctt ccttctttct cttatttcca ttcctatata catgttcatc
     1621 atcttttctt ttatgaaacc tttcgaaaaa atgaaccatg atgtcatgca aagtaattct
     1681 atggttagct ctgccattat cgaagatatc aacgggattg aaactataaa gtcgctcacg
     1741 agtgaagaaa atcgctatca aaatatagac agcgaatttg tagattattt ggaaaaatcc
     1801 tttaagctca gtaaatattc tattttacaa acgagtttaa agcagggaac aaaattagtt
     1861 ctgaatatcc ttatcctatg gtttggcgct caattagtca tgtcgagtaa aatttctatc
     1921 ggtcagctga ttacctttaa cacacttttt tcttacttta caactcctat ggaaaatatt
     1981 atcaacctcc aaaccaaact ccaatctgcg aaggtcgcta ataaccgttt gaacgaagtc
     2041 tatctagtcg aatctgaatt tcaagttcaa gaaaaccctg tccattcaca ttttttgatg
     2101 ggcgatattg aatttgatga cctttcttat aagtatggtt ttggacgaga taccttaaca
     2161 gatattaatc tcacgattaa acaaggagat aaggttagcc tagttggagt tagtggttct
     2221 ggtaaaacaa ctttagccaa aatgattgtc aatttctttg aaccctacaa aggacatatt
     2281 tctatcaatc atcaggatat taaaaacatt gataaaaaag tcttgcgccg tcatattaat
     2341 tacctaccac aacaagccta tatctttaat ggctctatct tggaaaactt aactttgggc
     2401 ggtaatcata tgattagcca agaagatatt ctaagagctt gtgaattagc tgaaattcgt
     2461 caagacattg aaagaatgcc tatgggctat caaactcagc tctctgatgg agctggtcta
     2521 tcaggaggac aaaagcaacg aatagccctc gctcgtgctc ttttaactaa agctcctgtt
     2581 ttaatactag acgaagctac tagcggtctt gatgtcttga ctgagaaaaa ggttatagat
     2641 aatcttatgt ctctaactga taaaaccatt ctctttgtag cccatcgtct cagtatagcc
     2701 gaacgaacca accgtgtcat tgttcttgac caggggaaaa tcattgaagt tggtagtcac
     2761 caagagttaa tgcaggcgca aggtttctac catcatctat tcaataaata aggagaatgt
     2821 catgaatcct aatcttttta gaagcgtcga gttttatcag agacgttacc ataactatgc
     2881 gacagtgttc attatacctc tttcattact atttactttc atcttgattt tctcccttgt
     2941 tgccacaaaa gaaattactg ttacttccca aggagaaatc gcccctacaa gtgtcattgc
     3001 ctccattcag tcaaccagtg ataatcctat cctagctaat catttagtgg caaatcaagt
     3061 agttgaaaaa ggggacttac tcatcaaata ctctgaaaca atggaagaaa gtcagaaaac
     3121 tgccttagca actcaattac aaagacttga gaagcaaaaa gaaggacttg gaattttgaa
     3181 acaaagctta gaaaaagcga ctgatctttt ttctggcgag gatgaatttg gctaccataa
     3241 tacctttatg aattttacta aacaatccca tgatattgaa ctgggtatca caaagactaa
     3301 caccgaagtt tcaaatcaag ctaatctttc caatagcagt tcatcagcta ttgaacaaga
     3361 aattacaaaa gttcaacaac aaattggaga atatcaagag ttgagagatg ctatcataaa
     3421 taacagagca cgcttaccaa ctggcaatcc gcaccagtca attttgaatc gttatcttgt
     3481 agcctcacaa ggacaaacac aaggaactgc agaggagcca tttttatctc aaattaatca
     3541 aagtattgca ggtcttgaat catctatcgc aagcctcaaa attcagcaag ctggtatcgg
     3601 aagtgtagca acttatgata acagtttagc aaccaaaatt gaagtactcc gcactcagtt
     3661 tttacagaca gcctcacagc aacaactaac tgtggagaat caattaacag aattaaaagt
     3721 acaactagat caagccacac agcgtttgga aaacaatacc ttaacctccc caagtaaagg
     3781 tatcgttcat ctgaacagcg aatttgaagg taaaaataga attccaactg gtacagaaat
     3841 tgctcaaata ttccctgtca tcacagatac aagagaagta ctaatcactt actacgtatc
     3901 ttctgactat ctacctctac tagataaagg acaaactgta agattaaaac tggagaagat
     3961 tggaaatcac ggcaccacca tcatcggcca acttcagaca attgatcaaa ctcctaccag
     4021 aacagagcaa ggaaatctct ttaaattaac cgctcttgca aaactatcta acgaggatag
     4081 taaactcatc caatatggct tacaaggtcg cgtcactagt gtaactacaa agaaaacata
     4141 ttttgattat ttcaaagata aaattttaac ccattctgat taattttcag ataacactct
     4201 ataactattt attatcttat caaaaaggag aatcataaca tggataagaa acaaaaccta
     4261 acttcatttc aagaactaac aactaccgaa ctcaaccaaa ttacaggtgg aggattgtgg
     4321 gaagatttat tatataacat taatagatat gctcattaca tcacataaga acttcatcat
     4381 ccaatacaac tataaaaaaa taagaccgag aaacaagtac tctcggtctt atttttcatc
     4441 attctgtatg tatcacagta agtacctgac gaaagacttg attttgacag gtggtattta
     4501 gactggtatt aggatggctt tccacaatct tcatgacggt atagagacca actcctctct
     4561 cctccccttt agaactggct ccaaaggaga agatttcaga aatatcgatg ccctcttctt
     4621 tgatggagtt ttcgatgata aaggtctcct gtgctccatt ttttaaaaag gcgattgaaa
     4681 catgaggttg actagcttcc acactggctt caatagcatt gtcacaaagg atagacacaa
     4741 tggttagaaa atcaagtaga ctcatcccct cgacctgaat ctcctcagga acttcgacat
     4801 taaagacaat gttcttatct ctggctttta aaaatttccc tgctagaaga cttttgaggg
     4861 ctttatcacg aatatttacc aatctgccca ggtcatattt attgttctgc aatttctgac
     4921 tggaatcctt taagacggag ccatagacct cttttatctg ctccatatcc tcctcttcaa
     4981 tgcccagacg taagctagtc aagaggttgg tataatcatg acgaaagctc cgtacttcct
     5041 tgtaaagctc ctctatatgc cgactatagc gttccatatc tctatagcgc agggcctgct
     5101 cttgttccaa tctctcatag agtttttcct tcaaataggt atccaatttc ttgataaccc
     5161 ccataaaaaa gagtaggtaa aagactagga tgagatggcg aacagtcttt gattgaatac
     5221 tttgttcata ttcaaaaaaa gacagacttt ccatgactag atagtagcca cccattatcc
     5281 agttaatctg agtcagggac ttttgaaagg ctttatcgag aatctccttt ctcaagctag
     5341 taaaatcgta gtccaaccat ttcaaaaaag ctagagaaat gaagaaattg aaaattatta
     5401 tacataaccc agtaaatgag tagccatcat atacttgccc ttgtcccaaa aatggaagca
     5461 caaaatagga gactcctcta taaaagagat tcaccaatat cattggaaag agaccataaa
     5521 agaaaaggag ttttttagga agccctctca ataataagaa agataagcct atgccgtaca
     5581 agggttccat aaaataagat aggtaaacat ttcctactat atagctaatc atcacaaaaa
     5641 caaaggccaa cagtatctta aaaagaaagg ccttaaaaat cctctcgaaa gtaagatcaa
     5701 ttccatccac cttaaagaag atgacaattt ctagtccatt agtaacaagt gtatacaaca
     5761 atatccaagc aatgttcata aattctccta gctcagtgta atttattgat ggcctcagac
     5821 acttccctga ccttataacg ggcgattaga caacttccac cattgggaaa gaaaagcagt
     5881 ttttctttct tatccaaatg caccacattt gcaggattga tgagaaaaga gcggtggcac
     5941 tgcaagagac ggggctcctg cttgaaaacc tcctctaaac tcgctgtaaa ttccagcctg
     6001 tctgtcttgg tatagagaat aacacgatgg gctctgggcg acgtttcgag atagtaaacc
     6061 tctttaaaag gatactgaaa ttgggcaaat tttgatttaa agtaaaagca atcttccgcc
     6121 agacttttac tatcttgact attggcatag aggagggctg tctcgatccg agattcaaac
     6181 tcctctgctg acaaggcctt atcaatgtag tccaaagcag acacttggta gcgaaaagac
     6241 aggggcataa actccgagtg agtcgtcaca aagacaatca gggcataagg atcccgatcc
     6301 cgaatctttc tagccacttc cagtcccttc atctcttcat ttcgaatctc aatatccaaa
     6361 aagaatagct gatgggcccc cttctcatgc acttcagcca gcagttggtc cggcttgcca
     6421 aatacctcaa aagagctagg aatgatatga tgtgctttca aaagtttctc aatcgtcgtt
     6481 tcaattctag tctgttggga aaaatcatcc tctaaaacaa atattctcat cttcttactc
     6541 tccctctttc aaccattttt gacgaatttc tctatagcga cgtctggcat acttgacagc
     6601 gtattgacct tcttctccga gaaaaaggat tctttcttga aaatcaatcg attttaattt
     6661 atcaagatta accaaacaat ttcgatgaca tctcatcaag gtttccccac attggttctc
     6721 aagattactt aaattttgaa gcatattaaa actagcttct tctgtaacaa tctgtacggt
     6781 atgggcttta gttggatgtg tttggatata gtagatatcg tcgatgttta ctttatagac
     6841 tgttttctgc gtctgaataa tcatatattt cattggattc tcctcctaag aaaagaataa
     6901 cagaaaaggt ctagcccaag cacacccaat cctaaacagt ctttgaaaac tcctaaaagg
     6961 attattttct acaacatcat gatgagctta caactatttt atcataaaat tcactcagcg
     7021 caattcaaga catttcaatg acaattaaag atttgaataa aaaaaaagaa ttaaaagtga
     7081 taaactaaca gtatcaaaac acagttgcca gaagtaagac tggcacccag attaaaggag
     7141 gcattcccat gacagataca gaccccatca aaagagctca tactttgatt actgacttaa
     7201 acaaagccta ccaagcatgc aaacaggcaa gcgctgacga cgtccgcttt caggagcaat
     7261 taaactctat tcttggtttt ctagccaagg ctgaaacagt ggataatcga ttcttgattg
     7321 aactagaaaa attttaccag acttccagtc ttctcatggg actcagcgct cttgatccag
     7381 atgctccaac tcgcgccgct tggcgggcct atgaccgctt ccactttgac caagtcaaga
     7441 ccaagttaat actcaatgaa aatcaaagag caaactagga agctagccgc aagctgtact
     7501 tgagtacggt aagacgacgc tgacgtggtt tgaagagatt ttcgaagagt ataagtctct
     7561 acggaccaac cattatcctg tagtaacaaa aaagaagttg agacagactg aactcaactt
     7621 cttttttagt gtcgtatcag caatgttagt cctgcatctg acgttttacc tgataaggca
     7681 aatacaagac tagtaaaacc aaaccagctc ctagtaaggc tagaagggct agtttttctt
     7741 ggaaggtaat caacccaaca actaattcca caagtaaaac aaaactggtc aatcctcgaa
     7801 ctacctcctg taagcctttt tccttttgcc ccttgtccag cggaaagagt tgggtcaaat
     7861 actggtagtc aaagtcatga tagagggcca gcaactggaa gagcaagagg tagttaaaga
     7921 gaactaccac tgctgtcgca atccaagctt gctcgataaa aacctgcgcc agtacggaaa
     7981 gtaagagaag acgaagactg agagcaaaga ggtcgccatt tcgcagataa gaacgcagat
     8041 agagattttg ccaaatcttt ccagacacct tctgaacagc ctttaagata aagtccagat
     8101 aggcacgacg tttgacactg tttgaaattc cctttacctg cgtaaagagg gcaaagaaac
     8161 gaagcaagac ttgcttacgc ttgctttctt gggaaatgac atagtcccag tccagcccag
     8221 tttcagtgaa aaatttgctg gccttttgac gaaagtggaa atattttcct acccccaata
     8281 aaagcacata gagcagaaaa actggcaagc cataacccat tgctaaaaat aaaggcgcaa
     8341 ataacagcaa gaaaagggtc tgtacaaaga gccaaaagac tagggaaatg ccagtttgac
     8401 gcttgagatg gagcttgatt tcctcttctc caactaagag aaagagcttg tctggagcct
     8461 ccatataggt ggcaattcct ccccaaagta aaagtaaaac agacgtaatt cctacaaaca
     8521 aaaggatagg ccaatgattt tcaggaaaat gttgtaagag ttgactgtac tggtaggcta
     8581 gaaagcccaa caggacaagc aggaacaaga caaagtggtc attgagcaca tagcgcagat
     8641 aaccaaggca ctccttacga aaggcctgct ttctctttaa aaacaagtct ttcatagatc
     8701 ctcctctttg gtcagagcca agtaaatatc attcaaacta gcctcaggca tatcaaaggc
     8761 ttcacgtagt tgcaggagat tgcctttggc acgcacctct cccttgtgaa gaatgacaaa
     8821 ggcatcacac atcttctccg ccgaatccag cacgtgggta ctcatgagaa tagacttgcc
     8881 cttttgcttc tccacttcca aaagctgaat caaatcagaa atagccagcg gatcaagacc
     8941 aaggaaaggc tcatccacga tgaaaagact tggatccacc acaaaagcac agataatcat
     9001 gaccttctgc ttcatccctt ttgaaaaatg aacagggaac cagtctaatt tctgttccaa
     9061 acggaacatt tttaacaagg gctctactcg ttcgaaagcc actttttgct caataccgta
     9121 agccatagca accgtttcga tatgctctct gagggtcaat tcctcataca gactaggcgt
     9181 ctcaggaatg tagccaatct gcttgcggta gctagtcgca tctccttgca gagtcaggcc
     9241 attgatattg atggagccac tataaggtgc caacagaccg ataatctcat tgatcgtcgt
     9301 tgatttccca gcaccattga gaccaatcaa accgaccaac tgcccacttt caacagtaaa
     9361 ggacacatct ttcaaaacag ggacatgaac atagccacct gtcaggtttt taatttctaa
     9421 catattttct ccaaatctgg tataatgtag ctatattata tcaaaattca gtacagtaga
     9481 ggtagatttt atgtcagatt gcattttttg taaaatcatc gcaggggaaa ttcctgcttc
     9541 aaaagtatat gaagatgagc aggtccttgc ctttcttgat atctctcaag taacactagg
     9601 acacaccttg gtcgtgccaa aagaacacta tcgcaatctt ttggagatgg atgctacgag
     9661 cgccagccaa ctctttgccc aagtaccaaa agtagctcaa aaagtcatga aagtcactaa
     9721 ggctgctggt atgaatatca tttccaactg tgaagaagtc gctggtcaaa cagtttttca
     9781 tactcacgtt caccttgtac ctcgctacag tgctgacgat gacctcaaga ttgattttat
     9841 cgcccacgaa ccagactttg acaaacttgc tcaagtcgct gaaaccatca aaaacgctta
     9901 aggagttgct atgaaattat ccaacctact gctatttgca ggagctgcag ccggaagtta
     9961 tctggtcaca aaaaatcgcc aaaccatcac agatgaagtc ttgaatacca ctgaccgcgt
    10021 tcaagctatc aaggacgatg tggatattat ccaaaacagc ctgcaaatca ttgaccagca
    10081 aaaagaactt atcaaggaat accaagaaga cttgacttac aagtttaagg tcttggaaaa
    10141 ggatatccag actagactag ctgtgataaa agaaatgcag ggaactgaag ataagtaaaa
    10201 agagcccccc ggctcttttt taaaacgtaa acaagttata gtgaattgaa tttagaatag
    10261 cacatcatag tttctaaagc attgttagag attactttaa aatcctctta tcaatttgtt
    10321 catattctat ttcaatctac tatatatatc ccatcaacta tgcatcataa tttaggtaac
    10381 tcatactcaa taaaaatcaa aaagcaaact agaaagctag gcacagactg ctcaaaacac
    10441 cgttttaagg ttgtggatag aactgacgaa gtcagctcaa aacactgttt tgaggttgta
    10501 gatacgactg acgaagtcag ctcaaaacac tgttttgagg ttgtggatag aactgacgaa
    10561 gtcagtaacc atacccatga caagccgacg ctgacgtggt ttgaagaaat ttttgaagag
    10621 tatcattcac catttcacaa ctaaatcgaa gactttctgc cgtaatgaaa acacctgaaa
    10681 cagcttggtt tcggctgtcc ggaaacttta agacttaggt tcaaagttta ggtatggaac
    10741 ttcgaaggag gtcgctaccg tccgtcatta cttaggaaag tcttaaaaaa tcggctctat
    10801 aaagtaaaaa gagcccgaca gctctttttg tttatattca atgaaaatca aaaagcaaac
    10861 taggaaacta gccacgggct gctcaaaaca ctgttttgag gttgtagata cgacaagccg
    10921 acgctgacgt ggtttgaaga aatttttgaa gagtattatt ctccatcaaa ggcatcttta
    10981 atatggtcaa agaagccttt tttctttgga tttactttca agtcaccagc agccgcgaat
    11041 tctttcaagg ctactttttg gcggtcgttc aagcctgtcg gtgttacgac attaacagta
    11101 acgtattggt caccaactgc accgccacga aggctcggtg cccccttact acgtaggcgg
    11161 aatttcttac cagtctgagt tccctctgga ataaccaatt caacatcacc gtgaacagtt
    11221 ggaatatcta ctgtatcacc aagagccgct tggacaaagt tgaggttgag attgtagaag
    11281 atagtcgttc cttcacgttc aaacttgtcg ctagcttcta cagaaactac tacatacaag
    11341 tcaccataag gtccaccgtt aaagcctgct tcaccttgac cagcgaggcg aatttgttga
    11401 cctgtttcca caccagcagg gattttcaca tgtacgctat gagcttgttt ctcatgacct
    11461 gttccatgac aggttgtaca tggatatttg atttcttttc ctcgaccgtg acagacatca
    11521 caggttactt ggcgacgcat cataccaaga ggagtctgcg tatcgacgtt aatgacacca
    11581 gcgccatgac agcgtccaca agtgactgga cttgtccctg gcttagcacc agagccatta
    11641 catgtacgac agccagcttc acgatgatac ttaacttcct tctcagttcc gaagatagct
    11701 tcttcaaagg tcaaattgac acgatactgg agatcatctc cttggcgagg agcgtttgga
    11761 ttgcgcgaag aaccgcctcc gccgaagaaa cttgagaaaa tatcctcaaa accaccgaaa
    11821 ccacctgccc cattgaaacc gccgaaacca ccagctccac caaaaccacc attggcgcct
    11881 gcagcaccat actggtcata ggcagcacgt ttttggtcgt cactcaaagt ctcataggct
    11941 tcttgaactt ccttgtactt gtcctcagca ccaggctcct tgttgatatc tgggtgatat
    12001 tttttggaaa gcttacgata agcctttttg atttcgtctg ccgaagcgtt tttggatacc
    12061 cccagacgat cataaaattc agtattgttc ataattcaag atacaaaggg cgtcaaacgg
    12121 acacagccat ctaggagttt tgacgacgga cgcttacgtc ctagaaaaaa ctatcttttg
    12181 ggcacagtcc gtagcccgtg ttcagttacg aacaccctta ttcctttcta ttgatgttct
    12241 gaatcgaacc accatttagg tcgggttcaa ttcctttctt ttatatttag taagaaattc
    12301 tgaaacccgt gttcagttac gaacactctt tgttcccttc tattgatgag acaaaaccca
    12361 aacaaatgag attccgtccc tttttatcga aaaacagagg ctgggttgca acctctgcaa
    12421 ataagtaaat taactttatt ttgattttaa atatcctata agtacagaaa tatttatata
    12481 tttttgtctc ttcttagtat ttgcctatat aattccaatt gatcataaga aatacaacta
    12541 ctgtccaaat cataccaatt atgaacggta ttacaaattt atatgtttgt atttctaatg
    12601 atatcatagc tggtaccatc gccgatacaa atgcagacaa caatactgag gtaacaaaat
    12661 tccttaccgc ttcatcattt ttgatacaac tatcatgttc agctaatata att
//
LOCUS       DAVLBE010000051        12659 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.051, whole genome shotgun sequence.
ACCESSION   DAVLBE010000051 DAVLBE010000000
VERSION     DAVLBE010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12659)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12659)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12659
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.051"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(280..1446)
                     /locus_tag="VXB91_001605"
     CDS             complement(280..1446)
                     /locus_tag="VXB91_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEV0471023.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPIDRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKTEADVDQAVKEIGLPMIAKPDNGVGA
                     AATFKLETEDDINHFKQEWDHSTLYFFEKFVTSSEICTFDGLVDKDGKIVFSTTFDYA
                     YTPLDLMIYKMDNSYYVLKDMDPKLRKYGEAIVKEFGMKERFFHIEFFREGDDYITIE
                     YNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGEEFPASDFETQYCLATSRRANAHYVY
                     SEEDLLAKYSQQFKVKKVMPAAFAELQGDYLYMLTTPSRQEMDQMIADFGQRQE"
     gene            complement(1459..2283)
                     /locus_tag="VXB91_001606"
     CDS             complement(1459..2283)
                     /locus_tag="VXB91_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEV0471024.1"
                     /translation="MNQSYFYLKMKEHKLKVPYTGKERRVRILLPKDYEKDTDRSYPV
                     VYFHDGQNVFNSKESFIGHSWKIIPAIKRNPDISRMIVVAIDNDGMGRMNEYAAWKFQ
                     ESPIPEQQFGGKGVEYAEFVMEVVKPFIKHKTGWFDGMMTTGCSMGAYHALNFFLQHP
                     DVFTKVIALSGVYDARFFVGDYYNDDAIYQNSPVDYIWNQNDGWFIDRYRQAEIVLCT
                     GLGAWEQDGLPSFYKLKEAFDQKQIPAWFAEWGHDVAHDWEWWRKQMPYFLGNLYL"
     gene            complement(2418..3632)
                     /gene="thiI"
                     /locus_tag="VXB91_001607"
     CDS             complement(2418..3632)
                     /gene="thiI"
                     /locus_tag="VXB91_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HEV0471025.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYPQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSAVQEIMQDIYKE
                     GMTFKISSKRSDHTFELDSRELNQTLGGAVFEAIPNVQAQMKSPDINLQVEIREEAAY
                     LSYETVRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            complement(3641..4783)
                     /locus_tag="VXB91_001608"
     CDS             complement(3641..4783)
                     /locus_tag="VXB91_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEV0471026.1"
                     /translation="MIYFDNSATTRPYPEALETYMQVASKILGNPSSLHRLGDQATRI
                     LDASRQQIADLIGKKSDEIFFTSGGTEGDNWIIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKAQGFEVDFAPVDNKGFVDVEALEDLIRPDTTLVSIMAVNNEIGSIQPIEAI
                     SEFLADKPTISFHVDAVQALAKIPTEKYLTERVDFATFSGHKFHGIRGVGFIYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIRQALL
                     DYPDIFVFSDEEDFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAQSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            4921..5349
                     /locus_tag="VXB91_001609"
     CDS             4921..5349
                     /locus_tag="VXB91_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0471027.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTITTIGSILGLITAGITIMN
                     ALDNNNKNTKKEPTTSQTTTFVKEIQKESPQENTTPNKENNTSQEKTQQEETPKSSVK
                     EEKKEDQKTATQDSTTPATSKPATENEKQPNTPTSENNTQ"
     gene            complement(5500..7725)
                     /locus_tag="VXB91_001610"
     CDS             complement(5500..7725)
                     /locus_tag="VXB91_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEV0471028.1"
                     /translation="MLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGSLAYLAIFGL
                     LIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGTMAQVVTDLT
                     GFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWSVYDIAEFFS
                     RGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPPVDMETGEIL
                     TEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDEDVQVDFSAKEALEYKLPS
                     LQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGPSVTKYEVKPAVG
                     VRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFRELWEQSQTK
                     AENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASILMKARPDQV
                     KFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFAKVGVRNI
                     AGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     IDENHPVRLQGSFISDDDVERIVNFIKTQADADYDESFDPGEVSENEGEFSDGDAGGD
                     PLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEMAGVIGPAEGTKPRKVLQ
                     Q"
     gene            complement(7889..9841)
                     /locus_tag="VXB91_001611"
     CDS             complement(7889..9841)
                     /locus_tag="VXB91_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0471029.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIDEMIKNLTEHSYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSADQVIELFDQASEKTEELVQVP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLALSGDTEVYRAANGAK
                     AATASNEKQSLGGAFYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALGVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            complement(9838..10749)
                     /gene="pfkB"
                     /locus_tag="VXB91_001612"
     CDS             complement(9838..10749)
                     /gene="pfkB"
                     /locus_tag="VXB91_001612"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HEV0471030.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLNIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVEPVQLEELKAILSSLTAEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSEGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDAVEAFKWGVACG
                     TATTFSDDLATAEFIKETYGKVEVEKR"
     gene            complement(10746..11486)
                     /locus_tag="VXB91_001613"
     CDS             complement(10746..11486)
                     /locus_tag="VXB91_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV0471031.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPHSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNVTVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            11649..11736
                     /locus_tag="VXB91_001614"
     tRNA            11649..11736
                     /locus_tag="VXB91_001614"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:11683..11685,aa:Ser,seq:gga)
     gene            complement(11919..12266)
                     /gene="ssrA"
                     /locus_tag="VXB91_001615"
     tmRNA           complement(11919..12266)
                     /gene="ssrA"
                     /locus_tag="VXB91_001615"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
BASE COUNT         3720 a         2829 c         2420 g         3690 t
ORIGIN      
        1 gtttgctctt tgattttcat tgagtattaa tagactggtt tggtatcctg aaaactatat
       61 cgtataggtg tcgtcatgga tccttttagc tgatttaagg atacgaaaac acaatactat
      121 gactaaattg aaatgttaaa attcaatttc tagccaccta atcctgcttc aaatagttat
      181 cgaacaagtt ttatgatagc taccttgtta ggatgctctt attttttacc agacaaaaca
      241 aaaggattaa gggagtgaat ttccttaatc cgatagttct tattcttgac gttgtccgaa
      301 atcagcaatc atctgatcca tttcttgtcg actcggagtt gtcagcatat acaggtaatc
      361 tccttgaagt tccgcgaagg cagctggcat gactttttta accttgaact gctggctata
      421 tttggcaagc aaatcctctt ctgaataaac atagtgagca tttgcacggc gagaagtagc
      481 caaacaatac tgagtttcaa agtctgacgc cgggaactcc tctcctgcga caatagctgc
      541 atagccacga taaaggtcca aggaatgagc aaagttataa acatcaatgg taaaaccacc
      601 tgcagggcgg ttattgtact cgatggtaat ataatcgtcc ccctcacgga agaactcaat
      661 atggaaaaac cgttctttca taccaaattc tttgacaatt gcttccccat acttgcgcag
      721 tttaggatcc atatccttga gcacataata agaattgtcc atcttataaa tcatgaggtc
      781 aagcggtgta taggcgtagt caaaggttgt tgagaagaca atctttccat ccttgtccac
      841 gagcccgtca aaggtacaga tttcgctgga agtgacaaat ttttcaaaga aataaagggt
      901 tgaatggtcc cattcttgct tgaagtgatt gatatcgtct tctgtctcaa gtttaaaggt
      961 tgcggctgct cccactccat tatcaggttt ggcaatcatt ggaagaccga tttctttcac
     1021 tgcttgatca acatctgctt ccgtcttgat aacagctcca ggtaccacag gaacacctgc
     1081 ttttttgaaa agtttcttca tttcagactt atatttcgtc tttttgagat cctctggttt
     1141 ggcaccaaaa acattgaatt gttctctgag tgttgcgtct agctcaagcc agtattcatt
     1201 gtgagactcg atgcggtcaa ttggaccatg tttataaaag agaaaagcaa ctgcacgttt
     1261 gacttcatct atgttctcaa gattatcaac acgaaaatac tcggtcaagc tattgcgcaa
     1321 gggctcatcc aattgctcgt aagactcttg accaattccc aagactgtga tgcctttatt
     1381 agctagttcg atggtaaact gttgaaagtt ttgtggatag tagggagaaa taacaaggta
     1441 attcataggt aactcctttt ataaatagag attaccgagg aaataaggca tttgtttacg
     1501 ccaccattcc cagtcgtggg cgacatcatg tccccattca gcaaaccagg ctggaatttg
     1561 tttctggtca aaggcttctt tgagcttgta aaaggatggt aaaccatctt gttcccaggc
     1621 tccaagcccc gtacacagca caatctctgc ctgacggtaa cggtcaataa accagccatc
     1681 gttttggttc caaatataat ctactggcga gttttggtaa atagcatcat cgttgtagta
     1741 atcgccgaca aagaaacgtg cgtcgtaaac accactgaga gcaatcactt tggtaaagac
     1801 atctggatgc tggaggaaga aattgagtgc atgataggct cccatagagc aacctgtcgt
     1861 catcatgcca tcaaaccaac ctgttttgtg cttgataaaa ggcttgacca cctccatgac
     1921 aaactcagca tactccacac ccttaccacc aaactgctgc tctgggatag gagattcttg
     1981 gaacttccaa gccgcatact cattcatccg ccccatacca tcattgtcaa tagcaacgac
     2041 aatcatgcga ctgatatccg gatttcgttt gatagctggg ataatcttcc atgaatgtcc
     2101 aatgaaagac tctttgctat taaaaacatt ttgcccgtca tgaaagtata caacaggata
     2161 ggaacggtct gtatctttct cataatcttt aggaagaaga atacgtacac ggcgctcctt
     2221 acctgtataa ggaaccttga gtttgtgttc tttcattttt agataaaagt aggattgatt
     2281 cattgtcaga aaactctcta tattcaaaat tttatatcat tatatcataa aaataaaaaa
     2341 agttagtttt ttacctgttt ttagagaaaa aactaacttt ttttactgat tttcgctatt
     2401 cttttggatt ttctgaatta gagcagattg tcaatcaagt catcaacttc atctttttcg
     2461 gcttgaggtg tgatttcagt aatcatgatt ccagccactg ctcgctcaac caagccttca
     2521 acatccatac gcgcttcgta ctgctccgca ttcttaattt taggatttgt ttttggacga
     2581 tctggtgcaa aaatagtaca acagtcttca aacggttgga ttgaaatgtc aaaggtatcg
     2641 atttcctggg cgatgtcaat gatttccaac ttgtccatgg taaccacagg acgaatgatg
     2701 ggagtgttgg taacagcatt gatagccttc atactttcaa gggtttggct ggctacttga
     2761 cctagacttt ccccattgat gataactaaa ccatttcgta cctcacgaat acggtcagta
     2821 atacgcatca taaaacgacg cgtcaaggtc ataaggtagg cttctggcgc tttggctttg
     2881 atttcctctt gaatctctgt aaaaggaact tcgataaact ggatatttcc cccaaatttg
     2941 gttaatttac gggtcaaatc ttgggctttt ttaagagcac caggactcgt gtaaggtggg
     3001 ctggcaaagt gaactgcctc tatatctacc cctcgtttaa gcgctagata gccagctaca
     3061 ggggaatcga ttccccctga caacatgagc atgcccttac cagaagttcc cactggtaat
     3121 ccacctgccc ctcgaacggt ttcataagaa agataggctg cttcttcacg tatctccacc
     3181 tgaagattga tgtcaggact tttcatttga gcttgtacgt ttggaatggc ttcgaataca
     3241 gcccctccaa gcgtttggtt gagttcacga ctgtccaatt caaaggtgtg gtcgctacgc
     3301 ttgctagaga ttttaaaggt catgccttcc ttgtagatgt cctgcataat ctcttggaca
     3361 gcagacttca gaacttctac agatttttca accttataaa caggggaaaa gttttgaatt
     3421 ccaaatactt gtttgagcga ttctgctact gctgtgtaat ctgctccatt gaggtaagcg
     3481 tgggcacggt cgcgatctgc tgttacctta acttggggat agatagacaa aacgtctgaa
     3541 atattattgc gaagtttatt gatgaaacgc atacgatttt tgcccttggt tgacagctca
     3601 ccgtagcgaa tcataatttc tgaatactgc atgaatgctc ctatcttact tttctagttt
     3661 gattgtaaat taattttagc ttggtcaaga actgctcgac ctgactcata tcattttcaa
     3721 ggtctagact aagacgcaca gctgactgag ccttatcctt gtccactccc atagcaatca
     3781 gggttccggc tggtttccca gccttggacg aacaagccga ggtcgttgag atgaaaatat
     3841 catagtcttc aaaggcgtga acaatgacct caccacgaac acccttgatt ccaaaagtca
     3901 gaatatgagg ggcgaagtct tcctcatctg aaaagacaaa tatatccgga tagtccagaa
     3961 gtgcttgacg aatcactgcc ttcatctgcc cagtcttgct cctaaagata tctagctttt
     4021 ccatagataa acggagagcc ttagcggtcg ctgcaattcc tgccacattt tcagttgtcg
     4081 aacggtaatc acgttcctga ccaccacctg ttaaaagagg cgtaatcttc ttgccagact
     4141 tgatatagat aaaaccaaca ccacggattc cgtggaactt gtgaccagag aaagtcgcga
     4201 aatccactcg ttctgtcaga tacttttcag tcggaatctt ggcaagcgcc tgaaccgcat
     4261 caacgtggaa ggaaatagtt ggcttgtctg ccaagaattc tgaaatagcc tcaataggtt
     4321 ggatagagcc gatttcattg ttcacagcca tgatggaaac gagggtcgta tcaggtctta
     4381 tcaaatcttc tagcgcctca acatccacaa atcctttgtt atcaactgga gcaaaatcca
     4441 cttcaaaacc ttgagctttc aaccagaggg ctgattcctt aactgctgga tgttcaatgg
     4501 ctgatacgat gatgtgcttg ccaaactggg ctttttcaaa tgctactccc ttgatgatcc
     4561 agttatcccc ttctgtccca ccagatgtaa agaagatttc atcacttttc ttaccgatta
     4621 aatctgcaat ctgttgacgg gaagcatcta aaattcgtgt tgcctggtct cccaaacgat
     4681 ggagactaga tggatttcct aaaatttttg aagccacctg catataggtt tcaagggctt
     4741 ctggataggg cctggtcgtc gccgaattat caaagtaaat catgtttctc acgctttcta
     4801 aaatcactcc ttctattgta tcatgaaacg gagcctgcga caagaaaggg caatttctct
     4861 ttttttaaga tttttttaaa gaaacagagt ataataaatc ataatcaaag gagagaatgt
     4921 atgtctaact atcgtagaac ttcaaaaccg aaaacagaac atatcaaaaa aggctttact
     4981 gtttttcaaa aaaccattac tactatcggt agtatccttg gtttgattac cgcgggtatc
     5041 acgatcatga acgccttgga taataataat aaaaatacta aaaaagaacc tacgacaagc
     5101 cagacgacaa cctttgtcaa agaaattcaa aaagaatccc ctcaggaaaa tactactcca
     5161 aataaggaaa ataacacttc tcaagaaaaa acacaacaag aagaaacgcc aaaatctagc
     5221 gtcaaggaag agaaaaaaga agatcagaaa acagcaactc aggactctac tacacctgct
     5281 acaagtaaac ctgccactga aaatgaaaaa cagcccaata ctccaacttc agaaaataat
     5341 actcaatgaa aatcaaagag caaactagga agctagccgt agacagtact tgagtacggc
     5401 aaggcgaagc tgacgtggtt tgaagagatt tgcgaagagt ataaaagtaa tcaatagcca
     5461 gtaaaatagc tccttccaac cttggaaaga agctattttt tattgctgca atacttttct
     5521 tggcttggta ccttcagctg gaccaatgac acctgccatc tcaagctctt ccatgagacg
     5581 ggtcgcacgg ttaaatccaa ctgacaaacg acgctgaatc atggatgcac tggctttctg
     5641 tgtttcgata accaaagact tagcttcttc aaaaagcgga tcaccaccag catctccatc
     5701 cgaaaattct ccttcatttt cagaaacctc acctggatca aaactctcat cgtagtctgc
     5761 atctgcctga gtcttgatga agttcacaat gcgctcaaca tcgtcatccg agataaagga
     5821 gccttggaga cgaactggat gattttcatc aatcggttta aagagcatgt ctcctcgacc
     5881 aagaagtttt tctgctccat tttcatccaa aatcgtacgg gagtctgttc ctgatgaaac
     5941 cgcaaatgct acacgagatg gaacattggc cttaatcaaa ccagagatga catcaacaga
     6001 tggacgctga gttgcaagaa tcatgtggat acctgcagca cgcgccttct gcccaagacg
     6061 gatgatagca tcttccactt ccttgctggc caccatcatg aggtcagcca actcatccac
     6121 aatcacgaca atgaatggta gcggaatttg cttgtactca gactgggaat tgaactcttc
     6181 taccttggca ttaaaacctg caatattccg aactcccacc ttggcaaaga gttcataacg
     6241 gttttccatt tcatccacaa ccttttgcag agccttgctg gctttgcgtg gattggtcac
     6301 gactggaatc aagaggtggg gaatatcatt gtaaacagat aactcaacca tcttgggatc
     6361 gaccatcata aatttaactt gatctggtct cgccttcatg agaatgctag caataatgcc
     6421 gttaactgct actgacttcc ctgaacccgt tgaacctgca actagcaagt ggggcatttt
     6481 agaaaggtca aaagctcttg cggttccatt aacagccttc cctaaaggaa tttccaagaa
     6541 attttctgct ttcgtttgcg attgttccca tagttctcgg aaagatacag tggcaatatc
     6601 ggagttgggc acttcaattc cgattaggga tttcccaggg attggtgctt caatccggac
     6661 atctttggca gccaaggcta gagcgaggtc atctgataga ttggaaatgc ggttgaccct
     6721 tacaccaaca gccggcttga cttcatactt ggtcactgat ggcccaattt cggcccgttc
     6781 aactgttacc ttaataccaa agctagcaaa ggttgcttct aagattttga tattttctct
     6841 gacaattttc ttctctttag actgatcttt tggtttatct ggtgcaaaga gttgtaagct
     6901 tggaagtttg tattcaaggg cttctttggc tgaaaaatcg acctgaacat cttcgtcatc
     6961 tgagtcatct tcctgttcag ggaatttaag ttcagcttga ggcaggatga tttctggttc
     7021 cacccacttt tcttctggaa taggtggaag attttgaaca gcttcctctg tcagaatttc
     7081 acccgtttcc atatcaacag gaggcaaatc gagtaaggct ttttcagtct cttcttgttc
     7141 taatctagcc tctttctcag ccttttggcg agctttttct tcttgtttga caaagcgttc
     7201 ctcttttcga cgctcgtgcc cttcccacca tttggcaaag cctctactga aaaattcagc
     7261 aatatcgtaa acagaccaag ggctgactag gagagaaccc actaaaatca agatagaacc
     7321 aataaagtaa gttccgatat ttgaaaagag aaaagctgtt ggaatataaa gagcgacccc
     7381 gatcaagccc cctccagcaa aactagtcgt tcgaaaacca gtcagatctg tcacaacctg
     7441 agccatggtc ccttttagaa cggacttgtc caaaccatat ttccaaacca agtaggcttc
     7501 aaaaatcaag agtaagccag caaatatggt gaaaaagcca gataagagtc cttcctgttt
     7561 tcgtatccac ttgaaaaaaa agagatagat taataggccg aatatcgcca gataagctag
     7621 gctacccact agcaagcgaa ttaaattata aagggttata cctgcagccc ctaatttgaa
     7681 ggctgcgaaa atcaataaaa tcgcaattcc taacgaaatc aacattcgtt gaatcgcttc
     7741 ttttctttcc agttctgctt tagacggtct ccgtcttgtt gtacttgtat tcttgtttgc
     7801 cattcttcta ttataccata tttcacaggc atttcggaaa gagaaaaaga ctgcaccaaa
     7861 cggtccaatc ttttcatttt tctatttttt atgcttgtgg tttgcgtagg taaccataaa
     7921 ccacaccact tacgattgct cctaccaaga cagaaacgag gtaaaggaga gcatttgaag
     7981 taagggcgat aacgaagatt cctccgtgtg gcgccatgag tttaatacca gtaagaccaa
     8041 cgagtccacc tgctactgct gaaccaagga tgaagcttgg aatcgcacga gctgggtcag
     8101 cggcaccaaa tggaatcgct ccctcagtga taaatgacaa gcccatgatg atgtttgtca
     8161 aaccagagtt acgttcttcc ttagtaaatt tatctttgaa aagaagagtt gcgacaaaga
     8221 ttgcaagtgg tggcaccatt cctccagcca taactgctgc catggctaca gaaccacctg
     8281 aagaaacagt tgctgcaagc gtacctgtac caaagacata agctgcttta ttaactggtc
     8341 cacccatgtc aacagccatc attccaccaa ggacgatacc aagaaggaca gctgaacctc
     8401 ctccaagacc gcctaggaag tcattcatag cagtgttgat tgctgccatt gggatattca
     8461 cagctagcat aacaaatcct gtcaagattg ttccaagaag tggcaataga aggattgatt
     8521 tagcaccttc gagtgaacga ggaactttaa cgtatttctt gatggcaaga accaaggcac
     8581 ctgcgataaa tccaccaaca agggcaccta ggaaaccaga tgagacacct gcaagagttg
     8641 aagttgcttc accacctgcg gcataaggaa ttttaccaaa ggcaaaacct tctttggcaa
     8701 tagcaccagc cacgaaacct gctaccaaac ctggtttttc agcaatagag taggcaacat
     8761 aacccgcaaa gactggaagc atcaaaccaa aggcagctcc accaattttc atgaacatag
     8821 aagctaactc atggtaagaa ccaagattgc caaggttttc atttggaaca cccaaagcac
     8881 cgtcaatcaa gaaggcaagg gcaatcatga taccaccacc gataacgaat ggtaacattt
     8941 gagatacacc actcatcaag tgtttgtaga aggcaccacc aaggctttgt ttttcgttag
     9001 aggctgttgc agcttttgca ccattagcgg cacggtagac ttcagtatct cctgaaagag
     9061 ccaagttaat tagctcttct gtcttacgga taccgtcagc aactggacga ttgatcaatg
     9121 gttttccatc aaatcgatcc atttcaacgg ccttgtctgc tgcaatgata atagctttag
     9181 ccttacggat atcttctgca gttagttgat ttccaacacc gctagcaccg ttggtttcga
     9241 ccttgatacc aacccccatt tcagcagcta ctttttgaag ggcttcttgg gccatgtaag
     9301 tgtgggcaat acctgttgta caagctgtaa cagctacgat aaagtcacca gagtcattag
     9361 caggtacttg aacaagttcc tcagtttttt ctgaagcttg gtcaaaaagt tcgataactt
     9421 ggtctgcaga tgttgcttga cgaagtttgt ctgcaaaacc gtctttcatc aagtattgag
     9481 acaattctgc caaggctgcc aagtgagtat cattggcacc ttctggagct gcaatcatga
     9541 agaagaggtc agttgcttgt ccatccaagc tctcgtagtc aacaccctta tttgacttag
     9601 caaatagaac tgtcgcttct ttgacagcag cgtttttgct gtgaggcatt gcgattccat
     9661 cacccaaacc agtagaagtc aaagcttcac gcgccaaaat tccttcttta aatgtttcaa
     9721 aatctgttac ataactgtgc tctgtcaaat ttttaatcat ctcgtcgatg acagctgttt
     9781 tttcagttgc ctgcaaatct agcaacatga catcttttct caataggtct tgaattttca
     9841 tcttttttct acctcaactt ttccatatgt ttctttaata aattccgccg ttgccaagtc
     9901 atctgagaag gtagttgccg ttccgcaagc cactccccat ttgaaggctt ctactgcgtc
     9961 ttttgatttg acaaattcac ctgtgaatcc agcaaccata gaatcaccag ctccaactga
    10021 atttttgact gttcctttga ttggtttagc gaagtaagct ccctcagatg tgacaagaag
    10081 ggcgccatca ccagccatag agataataac attttgagca cccttagcca gtaactcacg
    10141 agcgtatttc tcaatttcat ctaaactttc gagtttaacc ccaaaaatcg ctccaagttc
    10201 atgattgttt ggttttacaa gaagaggctg gtagtccaaa ctatcaatta aggtctgtcc
    10261 ttcaaagtca cagaccactt gcgcaccagt ctggcgcgtc aaggaaatca aatccttata
    10321 gataacattg cctagatttt tagcacttga acctgcaaag acaactgtat cttctgctgt
    10381 cagactagat aaaatagctt tcaattcttc tagctgaacc ggttcaacag ttggacccgt
    10441 tccgttgatt tctgtttctt ggtctgcttt gattttaaca ttgatacgag tatcttctgc
    10501 cacctggaca aaacgtgtct cgatttcttc ctctgctaaa gtatctgtga taaatttacc
    10561 agtaaagcca ccgataaatc ccgtcgctgt atttggtata ttcaaacgtt tcaagacacg
    10621 gctgacattg attcctttcc caccagcaaa cttatcatca ctgtccatac gatttacact
    10681 accaactttg acttggtcca aacgaacgat atagtcaatg gatggattga gtgtgactgt
    10741 ataaatcata cttctattac ctccgttttc tccttaataa cctgcaagag ctcatgccct
    10801 tgactagtga taacgatagc gcgtttgagt ggtgctacct tggcaaagca agtttgtcca
    10861 atttttgacg aatccaccaa gacgtaggtc tgcttggcat tctccaaaat agctcttttc
    10921 acagctcctt cctccatatc aggagtcgta taatagccat cgtcaacacc attcattccg
    10981 ataaaggcac ggtcaaagtg caattggtta atctggttaa gagcaacgcc cccgatacta
    11041 gcatctgtcg ccgtcttgac gtttcctcca accatgacag ttggaatctg cttttcaacc
    11101 aactgagcgg catggtgaat ggagttggtc acaactgtaa cattcttatt gaccaattca
    11161 tgaatcaaaa aagcagttgt tgttccagca tcgataaaga tgacatcttt ttctttaatg
    11221 agagaggctg ctttctgagc cagcaacttc ttttcttgaa ggtttttgac agatttttct
    11281 tgaatggttt cttcttcctg taaggagtgg gggagttctg ctccaccatg cacacgacga
    11341 agcttgtttt ccgcttccaa ctcatccaag tctcttcgaa ccgttgattc tgacgtttct
    11401 agcaaactaa ctaatttttc tagagaaact acatgatgtt gatttaactc ctctaaaatt
    11461 agttgtttac gttctgtttt taacactgaa tcacctcctg ttatcgttta cactattcat
    11521 tctatcatac tttctttcga agtcaagcat tttttatcat tttctttcaa aatctatcat
    11581 tttttcttat ttctagaatt tttattgcaa gataagagcc tttatggtag actatttgag
    11641 taagtattgg aagattactc aagaggctta agaggccgtg ttggaaacgc ggtaggcgtg
    11701 taatagcgtg cgtgggttcg aatcccatgt cttccgtcga aaaaagatta tttctaggat
    11761 gcgacaaatg ttgtatcctt ttttctatcc tttttttaaa atagggtctg tttgtgactc
    11821 cctttttagc aaaagaatgc aaaggaatac caaagataaa aataaaaaac gttgatttaa
    11881 caacgtttta ccaaggaatg caaaagaatg caaaggaata atggagccgg tgggagtcga
    11941 acccacgtcc aaacacctgc caacatattt gtctacaacc ataggttatg tattatttta
    12001 acaacccctc gacacataac tcaagtctag aaactgcgag tctatcaatc tcttatcaag
    12061 ccgctagaca aggcttaatc gtatctcgct aataataaga cctgtcattg aacacgagca
    12121 atccaaatcg ggtcacgcct gctggttttt aggcagctag agcgtaagaa gtgttatttt
    12181 ttgcagttat atttaactga gcgtttacgt cgccacacga gtcgcaaaat atgcctcata
    12241 atgcctgtcg aatccgtaac gaccccaaaa gacaataaaa ccattatacc ttatctaact
    12301 caaaaatgca aaaagaaatc acatacctaa aaaagatact attcgagaaa tttagcaaac
    12361 tggaagacta actacaactt tctcagtgca taactttacg attgtaaata gagcttacga
    12421 aatccaatta acacatacct aagatgaagc tatctgtttt gaagaaattc acgaagagaa
    12481 ttattctaaa atactttcag atgagaattt tcgtactctc tttattttaa ttcatttgag
    12541 tttaaaaact ataaaatcaa tccttatatt attcggacta cttttcactt attgcaccaa
    12601 aatatagtaa aatgaaataa gaatagtacg aatagatcag gacagtcaaa tcgatttct
//
LOCUS       DAVLBE010000052        12638 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.052, whole genome shotgun sequence.
ACCESSION   DAVLBE010000052 DAVLBE010000000
VERSION     DAVLBE010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12638)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12638)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12638
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.052"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            8..1144
                     /gene="dnaN"
                     /locus_tag="VXB91_001616"
     CDS             8..1144
                     /gene="dnaN"
                     /locus_tag="VXB91_001616"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HEV0471032.1"
                     /translation="MIHFSINKNLFLQALNTTKRAISSKNAIPILSTVKIDVTNEGIT
                     LIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQN
                     QIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRP
                     ILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDD
                     IETVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSME
                     RARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYL
                     IDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRTN"
     gene            1209..1403
                     /locus_tag="VXB91_001617"
     CDS             1209..1403
                     /locus_tag="VXB91_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HEV0471033.1"
                     /translation="MYQVGNFVEMKKSHACTIKSTGKKANRWEITRVGADIKIKCSNC
                     EHVVMMGRYDFERKMNKIID"
     gene            1487..2602
                     /gene="ychF"
                     /locus_tag="VXB91_001618"
     CDS             1487..2602
                     /gene="ychF"
                     /locus_tag="VXB91_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HEV0471034.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            2674..3243
                     /locus_tag="VXB91_001619"
     CDS             2674..3243
                     /locus_tag="VXB91_001619"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEV0471035.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     QADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDDYIGI
                     LQSIDKVDDSVNYYLQEKNFEKTMQRYNG"
     gene            3244..6753
                     /gene="mfd"
                     /locus_tag="VXB91_001620"
     CDS             3244..6753
                     /gene="mfd"
                     /locus_tag="VXB91_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HEV0471036.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLTSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIVASRLILPSPNAFKDSIVKISVGEEYDQHAFIHQLKENG
                     YRKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERDLAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPMQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTNICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNIDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELILQIDAYLPDTYISDQ
                     RHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQRV
                     ERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKGLMELVFDVQNKKDYEI
                     LEGLLIFGESLLEIKEFKEENSI"
     gene            6811..7077
                     /locus_tag="VXB91_001621"
     CDS             6811..7077
                     /locus_tag="VXB91_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HEV0471037.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            7070..7438
                     /locus_tag="VXB91_001622"
     CDS             7070..7438
                     /locus_tag="VXB91_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HEV0471038.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGGVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            7558..8826
                     /locus_tag="VXB91_001623"
     CDS             7558..8826
                     /locus_tag="VXB91_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase-related serine hydrolase"
                     /protein_id="HEV0471039.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLSQSDFSIY
                     FREKLSSPMVYGEVPVYANEDLVVESGKLTPKTSFQITEWCLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKAWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            8823..10100
                     /gene="tilS"
                     /locus_tag="VXB91_001624"
     CDS             8823..10100
                     /gene="tilS"
                     /locus_tag="VXB91_001624"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HEV0471040.1"
                     /translation="MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYD
                     LAIAELSNNINVENLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEEEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ELIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            10104..10646
                     /gene="hpt"
                     /locus_tag="VXB91_001625"
     CDS             10104..10646
                     /gene="hpt"
                     /locus_tag="VXB91_001625"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HEV0471041.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKEREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            10662..12620
                     /gene="ftsH"
                     /locus_tag="VXB91_001626"
     CDS             10662..12620
                     /gene="ftsH"
                     /locus_tag="VXB91_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HEV0471042.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEGTGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAHHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMLGAQSPQKS
                     ISEQTAYEIDEEVRSLLNEARNKAAEIIQSNRETHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDEK"
BASE COUNT         4350 a         1908 c         2573 g         3807 t
ORIGIN      
        1 agaatccatg attcattttt caattaataa aaatttattt ctacaagcat taaatactac
       61 taagagagct attagttcta aaaatgccat tcctatttta tcaacagtaa aaattgacgt
      121 gaccaatgaa ggtattactt taattggttc aaatggtcaa atttcaattg aaaattttat
      181 ttctcaaaaa aatgaagatg ctggtttgtt aattacttct ttaggttcga tccttcttga
      241 agcttctttc tttatcaatg tagtatctag tttacctgat gtgactcttg attttaaaga
      301 aattgaacaa aatcaaattg ttttaaccag tggcaaatca gaaattaccc taaaaggaaa
      361 agatagcgaa caatatccac gaatccaaga aatttcagca agcactcctt taatacttga
      421 aacaaaatta ctcaagaaaa ttattaatga aacagccttt gctgcaagta cacaagagag
      481 tcgtccgatt ttaacaggtg tccacttcgt attgagtcaa cacaaagagt taaaaacagt
      541 tgcaacagac tctcatcgcc taagccagaa aaaattgact cttgaaaaaa atagtgatga
      601 ttttgatgtc gtaattccta gccgttctct acgcgaattt tcagcggtat ttacagatga
      661 tatcgaaact gtagagattt tctttgccaa taaccaaatc ctctttagaa gcgaaaatat
      721 tagcttctat actcgtctcc tagaaggaaa ctatcctgat acagatcgct tgattccaac
      781 agactttaac actactatta cttttaatgt ggtaaactta cgccagtcaa tggagcgtgc
      841 ccgtctttta tcaagtgcga ctcaaaatgg tactgtgaaa cttgaaatta aggatggggt
      901 tgttagcgcc catgttcact ctccagaagt tggtaaagta aacgaagaaa tcgatactga
      961 tcaggttact ggtgaagatt tgaccattag tttcaaccca acttacttga ttgattctct
     1021 taaagcttta aatagcgaaa aggtgaccat tagctttatc tcagctgttc gtccatttac
     1081 tcttgtgcca gcagatactg acgaagactt catgcagctc attacaccag ttcgtacaaa
     1141 ttaagtgaaa gaggttgagc ctggctcgcc tcttttatga tataatcgaa aaagaaaagg
     1201 agagtagtat gtatcaagtt ggaaattttg ttgagatgaa aaaatcacac gcttgtacaa
     1261 tcaagtcgac tggtaaaaag gctaatcgtt gggaaattac acgtgtagga gcagatatca
     1321 aaataaaatg cagtaattgt gagcatgttg tcatgatggg gcgatatgat tttgagcgaa
     1381 aaatgaataa aattattgac tgagaaccct tagttagagg gttagcactt tatccctttt
     1441 tgtgttataa tattagggat tgaaatgaaa acggagaatg agaaatatgg ctttgacagc
     1501 aggtatcgtt ggtttgccaa acgttggtaa atcaacatta tttaatgcaa ttacaaaagc
     1561 aggagcagag gcagcaaact acccatttgc gactattgat ccaaatgttg gaatggtgga
     1621 agttccagat gaacgcctac aaaaactaac tgaaatgata actcctaaaa agacagttcc
     1681 cacaacattt gaatttacag atattgcagg gattgtaaaa ggagcttcaa aaggagaagg
     1741 gctagggaat aaattcttgg ccaatattcg tgaagtagat gcgattgttc acgtagttcg
     1801 tgcttttgat gatgaaaatg tgatgcgcga gcaaggacgt gaagacgcct ttgtagatcc
     1861 acttgcagat attgatacaa ttaatctgga attgattctt gctgacttag aatcagtgaa
     1921 caaacgatat gcgcgtgtag aaaagatggc acgtacgcaa aaagataaag aatcagtagc
     1981 agaattcaat gttcttcaaa agattaaacc agtcctagaa gacgggaaat cagctcgtac
     2041 cattgaattt acagatgagg aacaaaaggt tgtcaaaggt cttttccttt tgacgactaa
     2101 accagttctt tatgtagcta atgtggacga ggatgtggtt tcagaacctg actctatcga
     2161 ctatgtcaaa caaattcgtg aatttgcagc gacagaaaat gctgaagtag tcgttatttc
     2221 tgcgcgtgct gaggaagaaa tttctgaatt ggatgatgaa gataaaaaag agtttcttga
     2281 agccattggt ttgacagaat caggtgtaga taagttgacg cgtgcagctt accacttgct
     2341 tggattggga acttacttca cagctggtga aaaagaagtt cgcgcttgga ctttcaaacg
     2401 tggtatgaag gctcctcaag cagctggtat tatccactca gactttgaaa aaggctttat
     2461 tcgtgcagta accatgtcat atgaagatct agtgaaatac ggatctgaaa aggccgtaaa
     2521 agaagctgga cgcttgcgtg aagaaggaaa agaatatatc gttcaagatg gcgatatcat
     2581 ggaattccgc tttaatgtct aaaaattaat aaatggtgtc aattaggttg gaaaaaaaat
     2641 tccaaccctt ttggcttttg aaaggaaaaa taaatgacca aattacttgt aggcttggga
     2701 aatccagggg ataaatattt tgaaacaaaa cacaatgttg gttttatgtt gattgatcaa
     2761 ctagcgaaga aacagaatgt cacttttaca cacgataaga tatttcaagc tgacctagca
     2821 tcctttttcc taaatggaga aaaaatttat ctggttaaac caacgacctt tatgaatgaa
     2881 agtggaaaag cagttcatgc tttattaact tactatggtt tggatattga cgatttactt
     2941 atcatttacg atgatcttga catggaagtt gggaaaattc gtttaagagc aaaaggctca
     3001 gcaggtggtc ataatggtat caagtctatt attcaacata taggaactca ggtctttaac
     3061 cgtgttaaga ttggaattgg aagacctaaa aatggtatgt cagttgttca tcatgttttg
     3121 agtaagtttg acagggatga ttatatcggt attttacagt ctattgacaa agttgacgat
     3181 tctgtaaact actatttaca agagaaaaat tttgagaaaa caatgcagag gtataacgga
     3241 taaatggtga ccttattaga tttattctca gaaaatgatc agattaaaaa atggcatcaa
     3301 aatttaacag ataagaaaag acaactaata cttggtttat caacatctac taaggctctt
     3361 gcaattgcaa gcagtttaga aaaagaagat aggattgtgt tattgacgtc aacttatgga
     3421 gaagcagaag gacttgttag tgatcttata tctatcttgg gtgaggaact cgtctatcca
     3481 tttttggtag atgatgctcc tatggtggag tttttgatgt cttcacagga aaaaattatt
     3541 tcacgggttg aagccttgcg ttttttgact gattcatcta agaaagggat tttagtttgt
     3601 aatatcgtag caagtcgatt gattttaccg tctcccaatg cattcaaaga tagtattgta
     3661 aaaatctcag ttggtgaaga atatgatcaa cacgcgttta tccatcagtt aaaggaaaat
     3721 ggctatcgaa aagttactca agtacaaact cagggcgaat ttagtcttcg aggagatatt
     3781 ttagatattt ttgaaatatc ccagttagaa ccttgtcgaa ttgagttttt tggtgatgaa
     3841 attgatggta tcaggtcatt tgaagtagaa acacaattat cgaaagaaaa taagacagaa
     3901 ctcactatct ttccagctag tgatatgctt ttgagagaaa aggattatca acgaggacag
     3961 tcagctttag aaaaacaaat ttcaaaaact ttatcaccta ttttgaaatc atacctagaa
     4021 gaaattcttt caagttttca ccaaaaacaa agtcatgcag actctcggaa gtttttatct
     4081 ttgtgctatg ataagacatg gactgtcttt gattatattg aaaaagatac cccaatattc
     4141 tttgatgatt atcaaaaatt gatgaatcag tatgaagtct ttgaaagaga cttagcgcag
     4201 tactttacag aagaattaca gaatagtaaa gcattttctg atatgcagta tttttctgat
     4261 attgaacaaa tctataaaaa acaaagtcca gtgacctttt tctctaatct tcaaaagggt
     4321 ttaggaaatc tcaaatttga caaaatttat caattcaatc aatatcctat gcaggaattt
     4381 ttcaatcagt tttcttttct aaaagaagaa attgaacgat ataaaaaaat ggattacacc
     4441 attattctgc agtctagcaa ttcaatggga agtaaaacat tggaggatat gttagaggaa
     4501 tatcagatta aattggattc tagagataag acaaatatct gtaaagaatc tgtaaactta
     4561 atagagggta atctcagaca tggttttcat tttgtagatg aaaagatttt attgataact
     4621 gaacatgaga tttttcaaaa gaaattaaag cgtcgttttc gaagacaaca tgtttcaaat
     4681 gcagagagat taaaagatta caatgaactt gaaaaagggg actatgttgt ccatcatatc
     4741 catgggattg gtcaatatct aggaattgaa accattgaaa tcaagggaat tcatcgcgat
     4801 tatgtcagtg tccaatacca aaatggtgat caaatttcta tccccgtgga acagattcat
     4861 ctactgtcca aatatatttc aagtgatggt aaagctccaa aactcaataa attaaatgac
     4921 ggtcatttta aaaaggccaa gcaaaaggtt aagaaccagg tagaggatat agctgatgat
     4981 ttaatcaaac tctactctga acgtagtcag ttgaagggtt ttgctttctc agctgatgat
     5041 gatgatcaag atgcctttga tgatgctttc ccttatgttg aaacggatga tcaacttcgt
     5101 agtattgagg aaatcaagag ggatatgcag gcttctcagc caatggatcg acttttagtt
     5161 ggggatgttg gttttggaaa gactgaagtt gctatgcgtg cagcctttaa agcagtcaat
     5221 gatcacaaac aggttgtcat tctagttccg acgacggttt tagcgcaaca gcactatacg
     5281 aattttaagg aacgattcca aaattttgca gttaatattg atgtgttgag tcgctttaga
     5341 agtaaaaaag agcagactgc aacacttgaa aaattgaaaa acggtcaagt cgatattttg
     5401 attggaacac atcgtgtttt gtcaaaagat gttgtgtttg ctgatttggg cttgatgatt
     5461 attgatgagg aacagcgatt tggtgtcaag cataaggaaa ctttgaaaga actgaagaaa
     5521 caagtggatg tcctaacctt gaccgctacg ccaatccctc gtaccctcca tatgtctatg
     5581 ctgggaatca gagatttatc tgttattgaa actccgccga ctaatcgcta tcctgttcag
     5641 acctatgttt tggaaaagaa tgatagtgtc attcgtgatg ctgtcttgcg tgaaatggag
     5701 cgtggaggtc aagtttatta tctttacaac aaagttgaca caattgttca gaaggtttca
     5761 gaattacagg agttgattcc ggaggcttcg attggatatg ttcatggtcg aatgagtgaa
     5821 gtccagttgg aaaatactct attagacttt attgagggac aatacgatat cttggtgacg
     5881 actactatta ttgagacagg ggtggacatt ccaaatgcta atactttatt tattgaaaat
     5941 gcggaccata tgggcttgtc aaccttatat cagttaagag gaagagtcgg tcgtagtaat
     6001 cgtattgctt atgcttatct catgtatcgt ccagaaaaat caatcagtga agtctctgaa
     6061 aagagattag aagcgattaa aggatttaca gaattgggct ctggctttaa gattgcaatg
     6121 cgagatcttt cgattcgtgg agcaggaaat cttttaggaa aatcccagtc tggtttcatt
     6181 gattctgttg gttttgaatt gtattcgcag ttattagagg aagctattgc taaacgaaac
     6241 ggtaatgcta acgctaacac aagaaccaaa gggaatgctg agttgatttt gcaaattgat
     6301 gcctatcttc ctgatactta tatttctgat caacgacata agattgaaat ttacaagaaa
     6361 attcgtcaaa ttgacaaccg tgtcaattat gaagagttac aagaggagtt gatagaccgt
     6421 tttggagaat acccagatgt agtagcctat cttttagaga ttggtttggt taaatcatac
     6481 ttggacaagg tctttgttca acgtgtggaa agaaaagata ataaaattac aattcaattt
     6541 gaaaaagtca ctcaacggct gtttttagct caagattatt ttaaagcttt atccgtaacg
     6601 aacttaaaag caggcatcgc tgagaataag ggattaatgg agcttgtatt tgatgtccaa
     6661 aataagaaag attatgaaat tttagaaggt ctgctgattt ttggagaaag tttattagag
     6721 ataaaagagt ttaaggaaga aaattccatt tgatattttt cttctataaa atagataaaa
     6781 atggtacaat aataaattga ggtaataagg atgagattag ataaatattt aaaagtatcg
     6841 cgaattatca agcgtcgtac agtcgcaaag gaagtagcag ataaaggtag aatcaaggtt
     6901 aatggaatct tggccaaaag ttcaacggac ttgaaagtta atgaccaagt tgaaattcgc
     6961 tttggcaata agttgctgct tgtaaaagta ctagagatga aagatagtac aaaaaaagaa
     7021 gatgcagcag gaatgtatga aattatcagt gaaacacggg tagaagaaaa tgtctaaaaa
     7081 tattgtacaa ttgaataatt cttttattca aaatgaatac caacgtcgtc gctacctgat
     7141 gaaagaacga caaaaacgga atcgttttat gggaggggta ttgattttga ttatgctatt
     7201 atttatcttg ccaactttta atttagcgca gagttatcag caattactcc aaagacgtca
     7261 gcaattagca gacttgcaaa ctcagtatca aactttgagt gatgaaaagg ataaggagac
     7321 agcatttgct accaagttga aagatgaaga ttatgctgct aaatatacac gagcgaagta
     7381 ctattattct aagtcgaggg aaaaagttta tacgattcct gacttgcttc aaaggtgata
     7441 aaatggaaaa tttattagac gtaatagagc aatttttgag tttgtcagat gaaaagctgg
     7501 aagaattggc tgataaaaat caattattgc gtttacaaga agaaaaggaa aggaagaatg
     7561 cgtaaattct taattatttt gttgctacca agttttttga ccatttcaaa agtcgttagc
     7621 acagaaaaag aagtcgtcta tacttcgaaa gaaatttatt acctttcaca atctgacttt
     7681 agtatttatt ttagagaaaa attaagttct cccatggttt atggagaggt tcctgtttat
     7741 gcgaatgaag atttagtagt ggaatctggg aaattgactc ccaaaacaag ttttcaaata
     7801 accgagtggt gcttaaataa acaaggaatt ccagtattta agctatcaaa tcatcaattt
     7861 atagctgcgg acaaacgatt tttatatgat caatcagagg taactccaac aataaaaaaa
     7921 gcatggttag aatctgactt taaactgtac aatagtcctt atgatttaaa agaagtgaaa
     7981 tcatccttat cagcttattc gcaagtatca atcgacaaga ccatgtttgt agaaggaaga
     8041 gaatttctac atattgatca ggctggatgg gtagctaaag aatcaacttc tgaagaagat
     8101 aatcggatga gtaaagttca agaaatgtta tctgaaaaat atcagaaaga ttctttctct
     8161 atttatgtta agcaactgac tactggaaaa gaagctggta tcaatcaaga tgaaaagatg
     8221 tatgcagcca gcgttttgaa actctcctat ctctattata cgcaagaaaa aataaatgag
     8281 ggtctttatc agttagatac gactgtaaaa tacgtatctg cagtcaatga ttttccaggt
     8341 tcttataaac cagagggaag tggtagtctt cctaaaaaag aagataataa agaatattct
     8401 ttaaaggatt taattacgaa agtatcaaaa gaatctgata atgtagctca taatctattg
     8461 ggatattaca tttcaaacca atctgatgcc acattcaaat ccaagatgtc tgccattatg
     8521 ggagatgatt gggatccaaa agaaaaattg atttcttcta agatggccgg gaagtttatg
     8581 gaagctattt ataatcaaaa tggatttgtg ctagagtctt tgactaaaac agattttgat
     8641 agtcagcgaa ttgccaaagg tgtttctgtt aaagtagctc ataaaattgg agatgcggat
     8701 gaatttaagc atgatacggg tgttgtctat gcagattctc catttattct ttctattttc
     8761 actaagaatt ctgattatga tacgatttct aagatagcca aggatgttta tgaggttcta
     8821 aaatgaggga accagatttt ttaaatcatt ttctcaagaa gggatatttc aaaaagcatg
     8881 ctaaggcggt tctagctctt tctggtggat tagattccat gtttctattt aaggtattgt
     8941 ctacttatca aaaagagtta gagattgaat tgattctagc tcatgtgaat cataagcaga
     9001 gaattgaatc agattgggaa gaaaaggaat taaggaagtt ggctgctgaa gcagagcttc
     9061 ctatttatat cagcaatttt tcaggagaat tttcagaagc gcgtgcacga aattttcgtt
     9121 atgatttttt tcaagaggtc atgaaaaaga caggtgcgac agctttagtc actgcccacc
     9181 atgctgatga tcaggtggaa acgattttga tgcgcttgat tcgaggaact cgcttgcgct
     9241 atctatcagg aattaaggag aagcaagtag tcggagagat agaaatcatt cgtcccttct
     9301 tgcattttca gaaaaaagac tttccatcaa tttttcactt tgaagataca tcaaatcagg
     9361 agaatcatta ttttcgaaat cgtattcgaa attcttactt accagaattg gaaaaagaaa
     9421 atcctcgatt tagggatgca atcttaggca tcggcaatga aattttagat tatgatttgg
     9481 caatagctga attatctaac aatattaatg tggaaaattt acagcagtta ttttcttact
     9541 ctgagtctac acaaagagtt ttacttcaaa cttatctgaa tcgttttcca gatttgaatc
     9601 ttacaaaagc tcagtttgct gaagttcagc agattttaaa atctaaaagc cagtatcgtc
     9661 atccgattaa aaatggctat gaattgataa aagagtacca acagtttcag atttgtaaaa
     9721 tcagtccgca ggctgatgaa gaggaagatg aacttgtgtt acactatcaa aatcaggtag
     9781 cttatcaagg atatttattt tcctttggac ttccattaga aggtgaatta attcaacaaa
     9841 tacctgtttc acgtgaaaca tccatacaca ttcgtcatcg aaaaacagga gatgttttga
     9901 ttcaaaatgg gcatagaaaa aaactcagac gtttatttat tgatttgaaa atccctatgg
     9961 aaaagagaaa ctctgctctt attattgagc aatttggtga aattgtctca attttgggaa
    10021 ttgcgaccaa taatttgagt aaaaaaacga aaaatgatat aatgaacact gtactttata
    10081 tagaaaaaat agataggtaa aaaatgttag aaaacgatat taaaaaagtc ctcgtttcac
    10141 acgatgaaat tacagaagca gctaaaaaac taggtgctca attaactaaa gactatgcag
    10201 gaaaaaatcc aatcttagtt gggattttaa aaggatctat tccttttatg gctgaattgg
    10261 tcaaacatat tgatacacat attgaaatgg acttcatgat ggtttctagc taccatggtg
    10321 gaacagcaag tagtggtgtt atcaatatta aacaagatgt gactcaagat atcaaaggaa
    10381 gacatgttct atttgtagaa gatatcattg atacaggtca aactttgaag aatttgcgag
    10441 atatgtttaa agaaagagaa gcagcttctg ttaaaattgc aaccttgttg gataaaccag
    10501 aaggacgtgt tgtagaaatt gaggcagact atacctgctt tactatccca aatgagtttg
    10561 tagtaggtta tggtttagac tacaaagaaa attatcgtaa tcttccttat attggagtat
    10621 tgaaagagga agtgtattca aattagaaag aataatcttt aatgaaaaaa caaaataatg
    10681 gtttaattaa aaatcctttt ctatggttat tatttatctt tttccttgtg acaggattcc
    10741 agtatttcta ttctgggaat aactcaggag gaagtcagca aatcaactat actgagttgg
    10801 tacaagaaat taccgatggt aatgtaaaag aattaactta ccaaccaaat ggtagtgtta
    10861 tcgaagtttc tggtgtctat aaaaatccta aaacaagtaa agaaggaaca ggtattcagt
    10921 ttttcacgcc atctgttact aaggtagaga aatttaccag cactattctt cctgcagata
    10981 ctaccgtatc agaattgcaa aaacttgcta ctgaccataa agcagaagta actgttaagc
    11041 atgaaagttc aagtggtata tggattaatc tactcgtatc cattgtgcca tttggaattc
    11101 tattcttctt cctattctct atgatgggaa atatgggagg aggcaatggc cgtaatccaa
    11161 tgagttttgg acgtagtaag gctaaagcag caaataaaga agatattaaa gtaagatttt
    11221 cagatgttgc tggagctgag gaagaaaaac aagaactagt tgaagttgtt gagttcttaa
    11281 aagatccaaa acgattcaca aaacttggag cccgtattcc agcaggtgtt cttttggagg
    11341 gacctccggg gacaggtaag actttgcttg ctaaggcagt cgctggagaa gcaggtgttc
    11401 cattctttag tatctcaggt tctgactttg tagaaatgtt tgtcggagtt ggagctagtc
    11461 gtgttcgctc tctttttgag gatgccaaaa aagcagcacc agctatcatc tttatcgatg
    11521 aaattgatgc tgttggacgt caacgtggag tcggtctcgg cggaggtaat gacgaacgtg
    11581 aacaaacctt gaaccaactt ttgattgaga tggatggttt tgagggaaat gaagggatta
    11641 tcgtcatcgc tgcgacaaac cgttcagatg tacttgatcc tgcccttttg cgtccaggac
    11701 gttttgatag aaaagtattg gttggccgtc ctgatgttaa aggtcgtgaa gcaatcttga
    11761 aagttcacgc taagaacaag cctttagcag aagatgttga tttgaaatta gtggctcaac
    11821 aaactccagg ctttgttggt gctgatttag agaatgtctt gaatgaagca gctttagttg
    11881 ctgctcgtcg caataaatcg ataattgatg cttcagatat tgatgaagca gaagatagag
    11941 ttattgctgg accttctaag aaagataaga cagtttcaca aaaagaacga gaattggttg
    12001 ctcaccatga ggcaggacat accattgttg gtctagtctt gtcgaatgct cgcgttgtcc
    12061 ataaggttac aattgtacca cgcggccgtg caggcggata catgattgca cttcctaaag
    12121 aggatcaaat gcttctatct aaagaagata tgaaagagca attggctggc ttaatgggtg
    12181 gacgtgtagc tgaagaaatt atctttaatg tccaaactac aggagcttca aacgactttg
    12241 aacaagcgac acaaatggca cgtgcaatgg ttacagagta cggtatgagt gaaaaacttg
    12301 gcccagtaca atatgaagga aaccatgcta tgcttggtgc acagagtcct caaaaatcaa
    12361 tttcagaaca aacagcttat gaaattgatg aagaggttcg ttcattatta aatgaggcac
    12421 gaaataaagc tgctgaaatt attcagtcaa atcgtgaaac tcacaagtta attgcagaag
    12481 cattattgaa atacgaaaca ttggatagta cacaaattaa agctctttac gaaacaggaa
    12541 agatgcctga agcagtagaa gaggaatctc atgcactatc ctatgatgaa gtaaagtcaa
    12601 aaatgaatga cgaaaaataa ccctgagaga ggctggag
//
LOCUS       DAVLBE010000053        12285 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.053, whole genome shotgun sequence.
ACCESSION   DAVLBE010000053 DAVLBE010000000
VERSION     DAVLBE010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12285)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12285)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12285
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.053"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            12..236
                     /locus_tag="VXB91_001627"
     CDS             12..236
                     /locus_tag="VXB91_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006531864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEV0471043.1"
                     /translation="MLAKVEGGYSSTDCQNALITGVTTGIITGGTGAGLATLGVAGLA
                     GAFVGAHIGAIGGGLTCLGGMVGDKLGLSW"
     gene            305..553
                     /gene="blpK"
                     /locus_tag="VXB91_001628"
     CDS             305..553
                     /gene="blpK"
                     /locus_tag="VXB91_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpK"
                     /protein_id="HEV0471044.1"
                     /translation="MDTKMMSQFSVMDTEMLACVEGGGCNWGDFAKAGVGGAAVVAAL
                     GCAAGGVKYGKILGPWGAAIGGIGGAVVCGYLAYTATS"
     gene            797..946
                     /gene="blpO"
                     /locus_tag="VXB91_001629"
     CDS             797..946
                     /gene="blpO"
                     /locus_tag="VXB91_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpO"
                     /protein_id="HEV0471045.1"
                     /translation="MNTKMMSQFSVMDNEMLACVEGGDIDWGRKISCAAGVAYGAIDG
                     CATTV"
     gene            1050..1169
                     /locus_tag="VXB91_001630"
     CDS             1050..1169
                     /locus_tag="VXB91_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000346296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEV0471046.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKIFSKSSKKDTDSTL"
     gene            1637..2008
                     /locus_tag="VXB91_001631"
     CDS             1637..2008
                     /locus_tag="VXB91_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0471047.1"
                     /translation="MIKKNHILCEIVPGSVAFACFYLSISISSVFQFLLVVINLTSIL
                     VTVYLTREMRLREFEDDDLVSPRTNQLMFIGLTGFMSIICLYRGITAGESYQQLIAYI
                     GAILCLIIMLLLIWGLKYYKK"
     gene            2637..3020
                     /locus_tag="VXB91_001632"
     CDS             2637..3020
                     /locus_tag="VXB91_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HEV0471048.1"
                     /translation="MKYRLFFVIFLSSVLDILLGTFLQISIVSIGWLVLYSGLFEAGV
                     FLLANKGVAVKIKEVDIRNRFKFIFGKTLWFQILLLIFLIIKLYLGLDARLILFYGHI
                     FIVFNALMYLLSSSQVSLKKNKLSS"
     gene            3072..3761
                     /locus_tag="VXB91_001633"
     CDS             3072..3761
                     /locus_tag="VXB91_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0471049.1"
                     /translation="MKKYQLLFKISAVFSYLFFVFGLSQMTLIIQNYWQFSSQIGNFV
                     WIQNFLSLLFSGVMIWILVKTGHGYLFHIPRKKWLWYSILTVLVVVLQISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYITLFFLTPLMEELIYRGLLQHAFFKHSRFGLDL
                     LLPSILFALPHFSSLPSLLDIFIFATSGIIFASLTRYTKSIYPSYAVHVINNIFATLP
                     FLLTFLHRVLG"
     gene            3803..4036
                     /locus_tag="VXB91_001634"
     CDS             3803..4036
                     /locus_tag="VXB91_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0471050.1"
                     /translation="MYKHLFFLDSKTLDRLTPYILVLASDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFIGAGYVVGFWLLILNENQRAN"
     gene            4187..4798
                     /locus_tag="VXB91_001635"
     CDS             4187..4798
                     /locus_tag="VXB91_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0471051.1"
                     /translation="MEFFDKFHALCFGFLVLIIVITVPYTINHGGFFQNESALILVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFGPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGFAYKKSQNLWVSTLVHMFYNSWPLLYYL"
     gene            4959..5753
                     /locus_tag="VXB91_001636"
     CDS             4959..5753
                     /locus_tag="VXB91_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HEV0471052.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETAPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            5750..6385
                     /gene="trmB"
                     /locus_tag="VXB91_001637"
     CDS             5750..6385
                     /gene="trmB"
                     /locus_tag="VXB91_001637"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HEV0471053.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEVGVPNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            6511..6990
                     /gene="rimP"
                     /locus_tag="VXB91_001638"
     CDS             6511..6990
                     /gene="rimP"
                     /locus_tag="VXB91_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HEV0471054.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEIISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMDKTRKKTVQIPYSLVSKARLAVKL"
     gene            7034..8170
                     /gene="nusA"
                     /locus_tag="VXB91_001639"
     CDS             7034..8170
                     /gene="nusA"
                     /locus_tag="VXB91_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HEV0471055.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            8192..8485
                     /locus_tag="VXB91_001640"
     CDS             8192..8485
                     /locus_tag="VXB91_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HEV0471056.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            8478..8777
                     /locus_tag="VXB91_001641"
     CDS             8478..8777
                     /locus_tag="VXB91_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HEV0471057.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLTKKIQDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            8794..11586
                     /gene="infB"
                     /locus_tag="VXB91_001642"
     CDS             8794..11586
                     /gene="infB"
                     /locus_tag="VXB91_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HEV0471058.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKAEKSEPAKPAVAKEEAKPAEPVAPKTEKVA
                     VKPQSRNFKAEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNR
                     RFNDQAKKQQGQQKRRNERRQQEDKRSNQAAPRIDFKARAAALKAEQNAEYARSSEER
                     FKQYQAAKEALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKK
                     QARPDKNRDDYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTP
                     KPVTERKFHELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGET
                     IELLMVDYGIEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTL
                     LDTLRNSRVATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDIT
                     ILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTA
                     WGGDSEFVEISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAV
                     ATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGD
                     HFAVYEDEKSARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADV
                     QGSVEALSASLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQAR
                     QQAEADDVEIRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIG
                     GFMVINGKVARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDGYNDI
                     KMDDVIEAYVMEEIKR"
     gene            11837..12187
                     /gene="rbfA"
                     /locus_tag="VXB91_001643"
     CDS             11837..12187
                     /gene="rbfA"
                     /locus_tag="VXB91_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HEV0471059.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
BASE COUNT         3737 a         2120 c         2768 g         3660 t
ORIGIN      
        1 tggatactga aatgcttgcg aaagttgaag gggggtatag ctccactgat tgtcaaaatg
       61 cactgattac aggagtcact acgggaatta taactggtgg aactggagca ggtttggcca
      121 ctttaggagt agctggactt gctggtgcat ttgttggagc acacattggt gcaattgggg
      181 gtggattaac atgcttagga ggtatggttg gtgataaatt gggactaagt tggtaagact
      241 tatagtaaaa ttatgaggat tctattctga tttattttag ttttttaaaa aaggagtatt
      301 tgtcatggat acaaaaatga tgtcacaatt ttctgttatg gatactgaaa tgcttgcttg
      361 cgttgaaggt ggcggatgca attggggaga ttttgccaaa gcaggtgttg gaggagcagc
      421 tgtagttgct gctttaggtt gtgcagcggg tggagtgaaa tatgggaaaa ttctaggacc
      481 atggggcgct gcaataggag gaattggagg agcagtggtt tgtggatatt tagcctatac
      541 cgctacatca taaaaatgaa agctaaattt tatgaaggct atattcttta ttattctctt
      601 cgcttttcaa acctatctta tttatctatc cataagtatc tctgataaaa aacaaaagac
      661 tattgaatta acatcattga attgttttgt catattattt ctaatctatg ataaattaat
      721 ttttctcttt attgcctatg tttttttgat aatttttata ttaaacttgt tccgtaactg
      781 aaaagtgaca tactatatga atacaaaaat gatgtcacaa ttttctgtta tggataatga
      841 aatgcttgct tgcgttgaag gtggagatat tgattgggga agaaaaatta gttgtgcagc
      901 aggggttgca tatggcgcaa ttgatgggtg tgcaacaacg gtttgacatt tctattggga
      961 ccatttgcta taggaatagg tgtaactggt gctgcaggtg gagctatact tggaggtgta
     1021 gcctatgcag caacatgttg gtggtaatta tggattttaa aagttttatt attggtttag
     1081 tagttggtat atttggtcct tatatggatg acttaattag aaaaatattt tcaaaatctt
     1141 ccaaaaagga tacggatagt actctctaaa aaataaattt ctcccctgta tttgctagct
     1201 taatttacag gggagtttct ttaatattgt ttcgcctgtc aaaatgatat gtgatagcag
     1261 gatgaaaagt ctacaaacaa gttggtatca atacaatata aagaggaaag tatgtttttc
     1321 atgcttgctt ttttaatttt tacaattcaa gaggttttga tgaccattta tgatttgagt
     1381 gatccaaggt caaaataagt gctatactag cagtgtaaat gttcttgctc aactaagata
     1441 aatcgcacat ttaggaggaa aacttatgaa gaaaaaaata ctgattattt tcgttctgta
     1501 tctgatcatg tccatctttc tttatccgct tagggagagt atttggtata atctatttta
     1561 taccatagcc tatatgattg cggttatgat ctatttttct ttaattaaaa agaaagaaaa
     1621 gaaatgaaag attttcttga ttaaaaagaa tcatattctt tgtgagattg ttcctgggtc
     1681 agttgccttt gcttgtttct acttatctat ttctatttcg tcagttttcc aatttctttt
     1741 agtagttatt aacttgactt ctattttggt tactgtttat cttactaggg aaatgagatt
     1801 aagagagttt gaagatgatg atttggttag tcctagaacc aatcaactca tgtttatcgg
     1861 cttgacaggc tttatgtcta ttatttgttt gtatagaggt atcacagcag gagaatctta
     1921 tcaacaacta atcgcttata ttggtgctat tctttgcttg atcatcatgc ttctactcat
     1981 ttggggtttg aagtattata aaaagtaggg gctaatgaag tttttgcaat ttaggaggtt
     2041 tcgatgacaa ttcaagattt ggatgaaaaa ttttaaaaaa caatgatata ctaaacttgt
     2101 caaagttgca acgggtgctg ctacattatg ttaaaaatcg ctcttgattg ataagttgga
     2161 tttgttagga aaggagtaaa taattatgga taagaaaaag atagtttcga ctataatatg
     2221 tatagtattt cttgtagtgt cagtagataa tttttttaga gacttaaccc cgttactgtt
     2281 cattttaaat attattggcc tgtcttgctt ttcagtgcta acatacatta acataaaaga
     2341 gatactctta aatataagta aatgatgatt tggttagtcc tagaaccaat caacttatgt
     2401 ttatcggctt ggcagatttt atgtttgtca tttgtttgta tagaggtatt tcagaaacag
     2461 aattctatca acaactaatc gcttatatag gtgtattctc tgcttgttta tcacgcttct
     2521 gctcatgtgg ggcttgaagt attataaaaa gtagctttct atccttttct gacaggatat
     2581 ttgagtagaa ggctctatta aattgttagt gaaataaatg aatggaggta tttaatatga
     2641 aatacagatt attttttgtt attttcttga gtagtgtgtt ggatattctt ttagggacat
     2701 ttttacaaat ctctatcgta tctattgggt ggcttgttct ttacagtggt ttgtttgaag
     2761 caggagtttt ccttcttgct aataaagggg tggcggtaaa aatcaaggaa gtagatattc
     2821 gaaatcgctt taaatttatt tttggaaaaa ccttatggtt tcaaattctt ttgctcatct
     2881 ttttgataat caaactttat cttggtttgg atgcgaggtt gattttattc tatggacata
     2941 ttttcattgt ctttaatgcc ttaatgtatc tattatctag tagtcaggtt agccttaaaa
     3001 aaaacaaact gtcttcttaa tcttacagca gtagagcctg acaaggtgag gtcatagtag
     3061 ggaggatttc tatgaaaaag tatcaacttc tattcaaaat aagtgcagtt ttctcttact
     3121 tatttttcgt atttggtctt tctcagatga cgcttattat tcaaaattat tggcaatttt
     3181 cttcccagat tggcaatttc gtctggattc aaaatttctt gagtttgcta tttagcggag
     3241 tcatgatttg gattctggtt aagacaggtc atggttatct ctttcacatt ccaagaaaaa
     3301 aatggctttg gtattcgatt ttgacagtat tagtggtagt gctccagatc tcttttaacg
     3361 ttcagacagc taaacatgtt cagtcaactg ctgaaggttg ggctgtattg atcggttata
     3421 gtgggaccaa ctttgctgag ctaggtatct atataacttt gttctttctg actccactta
     3481 tggaagagct aatctataga ggattactgc aacacgcctt ttttaagcat tcgagatttg
     3541 gccttgattt gcttcttccg tcaattttat ttgctcttcc tcatttttca agcctgccta
     3601 gtttgttaga tatcttcatc tttgcaacat ctggcatcat ctttgctagt ttgacccgct
     3661 ataccaagag catttatcct tcctatgcgg tgcatgtgat caataatatt ttcgcaacat
     3721 taccattttt gctgactttt ttacataggg tcttggggta aaaaaacaaa aggcttgctt
     3781 ttcagccata gaggagatta tcatgtataa acacttattt ttcctagatt ccaaaacttt
     3841 agatcggttg acaccctata ttctagtctt ggcttctgac accattgctt ttaatgtttt
     3901 tgtgctaacc tttgtatctg cggtggtttt taatttccta aattccatgc tagctttaat
     3961 ggctatattc ataggggctg gctatgtggt cggattttgg ttactaatac tcaatgaaaa
     4021 tcaaagagca aactaggaaa ctagccgcag gctgtacttg agtacggcaa ggcgacgttg
     4081 acgtggtttg aatttgattt tcgaagagta taaaatggtt tgttttggaa aggctagaac
     4141 taaagaatga cgcgtaggaa gtctgtttgg tgaggaggat agttttatgg agttttttga
     4201 taaatttcat gccttgtgtt ttggattttt agtactaata attgtcatta cagttcctta
     4261 tacgattaac catgggggtt tttttcaaaa tgaatctgca ttgattcttg taagtcttct
     4321 tgtaacctcg ctgagtgttg cttatgctag aaagtttgaa atgatttctt ttgggatgtt
     4381 aagcaagaaa caacttttgc ttttcattgc aatctttctt ctaagtgtac ttgagacgct
     4441 ggtttatatt catttcttcg ctgtttcttc tggctcaggg gtccaacact tggcggaagt
     4501 cagcagagga atttccctgt ctttgatttt gactacctca gtttttggcc ccatccagga
     4561 ggaactcatt ttcagaggac ttcttcaagg tgcggttttt gacaattctt ggttagggct
     4621 tgtgctaact tcctctctct tttctttcat gcatggacct tctaatgtcc cttcgtttat
     4681 tttttatcta cttgggggtt tgttgctggg ctttgcttat aaaaagagtc aaaacctatg
     4741 ggtttctact ctagtccaca tgttttacaa cagttggcca ctcctatatt atttataaaa
     4801 attatgaaaa ggtaagcaga agatggtgct tacctttttc aagctataat gatacccaag
     4861 ccaatccaga ggcttttctt tgagaatcgg gttagagtgg ttgacgaata ggccaaaaac
     4921 tagtagaata gtaaggaaac tttatacgga ggaaagaaat ggatttgggt gataatgagc
     4981 taacactgac tcccatacct gggaaaagtg gcaaggctta tatgggtagc tatcctgacg
     5041 ggaagcgcat ctttgtaaaa atgaacacct ctccaatcct acctggtcta gctagagaac
     5101 aaattgctcc acaattatta tggagtcgtc gtttggcaga tgggcgtgat atgtgtgctc
     5161 aagaatggtt gacaggcaag atattgaccc cctatgatat gaatcgtaag caaatcgtca
     5221 atattttaac ccgtcttcat cgctcacgtc cgttgatgac acaattgagt cgtttgggct
     5281 atgccatgga aacacctgta gatttactac agtcttggca ggaaacggct ccagatgctt
     5341 tgcgtaaaaa tcattttatc agtgaagtga tggctgattt acgtcagact attccaggat
     5401 ttagagagga ccatgcgacc attgtccatg gagatgtacg acatagtaat tggattgaga
     5461 cagatagtgg cttgatttat ttagtagatt gggattcggt tcgcttgacc gatcgcatgt
     5521 ttgatgtggc ccatatgctc tgccattata tttcagaaca tcagtggaag gaatggttga
     5581 cctactacgg ttacaagtac aatcaaacgg tattaagtaa attgtattgg tatggtcaat
     5641 tgtcttattt gagtcagatt tccaagtatt atatgaacca agatttagaa aatgtcaatc
     5701 gggagattca tggtttgcgt catttccgag acaagtatgg aaagagaaga tgagagttag
     5761 aaatcgtaaa ggggcaacag aattactaga ggcaaatccc cagtatgtgg tcctcaatcc
     5821 cttggaagcc aaggcaaaat ggcgggactt gtttggcaat gataatccca ttcatgtgga
     5881 agttggaagt ggaaagggtg cctttgtttc aggtatggcc aagcaaaacc ctgacatcaa
     5941 ctatatcggg attgatattc aaaagtctgt tttgagctac gctttggaca aggtgcttga
     6001 agttggagtg cctaacatca agctcttgtg ggtagatggt tctgacttaa ctgactattt
     6061 tgaagacggt gagattgatc gcttgtatct gaacttttca gatccatggc cgaaaaaacg
     6121 ccatgaaaag cgtcgtttga cctacaagac cttcttggat accttcaaac gtatcttgcc
     6181 tgaaaatgga gaaattcatt tcaagacgga taaccgtggc ttgtttgagt acagtttagt
     6241 gagcttttct caatatggca tgaaactcaa tggtgtctgg ttagatttgc atgccagtga
     6301 ttttgaaggc aatgtcatga cagaatacga gcaaaaattc tcaaacaagg ggcaagttat
     6361 ctaccgagtt gaggcagaat tttaagagat agcctaaaat taggctgtac aagtgctttt
     6421 gctttacata agttggcaaa cgtgctatac tgatagtaag aatatgaaaa gtgaggcggg
     6481 gaaatatctt cgcctcttgc ttatgaggag gtggacgcaa tcgcaacaat cgtagaatta
     6541 gtcagagaag ttgtagaacc tgtcatagaa gctccttttg aactcgtgga tatcgagtat
     6601 ggaaagattg gcagtgacat gattctcagt atttttgtag ataaacccga aggaattacc
     6661 ttgaacgaca cggcagactt gacagaaatt atcagtcctg tcctagacac catcaagcca
     6721 gatcccttcc cagaacaata tttcctagaa attaccagtc caggtttgga acgccctttg
     6781 aaaaccaagg atgccgtcgc tggagcggtt ggaaaataca tccatgtcgg gctctaccaa
     6841 gccatcgata agcaaaaggt ctttgaagga accttgttgg ccttcgaaga ggacgagttg
     6901 actatggaat atatggacaa gacgcgtaag aaaaccgtcc aaattccata cagtttagta
     6961 tcaaaagcac gtttagcagt taaattatag aaaaagaaag gatagctttt gaggattcaa
     7021 aagtgaagaa aacatgagta aagaaatgct agaggccttc cgcattttgg aagaagacaa
     7081 gggaatcaaa aaagaagata tcatcgacgc agtagtagag tcgcttcgtt ccgcttatcg
     7141 cagacgctat ggtcagtcag acagcgtagc tattgacttc aacgaaaaaa caggtgactt
     7201 tacagtttat actgtccgtg aagttgttga tgaagtattt gatagccgtt tggaaatcag
     7261 cttgaaagat gctcttgcca ttaattcagc ttatgaactt ggagacaaaa tcaagtttga
     7321 agaagcacca gctgagtttg gtcgtgtagc agcccagtct gccaaacaaa ccatcatgga
     7381 aaaaatgcgc aagcaaacac gtgccatcac ttacaatact tacaaagaac atgagcaaga
     7441 aatcatgtct ggtacagtag aacgctttga caaccgcttt atctatgtca accttggtag
     7501 catcgaagcc caattgtcaa aacaagacca aattcctgga gaagtttttg cttctcatga
     7561 tcgtatcgaa gtttatgttt acaaggttga agacaaccct cgtggtgtga acgtctttgt
     7621 tagccgtagt catccagaaa tgatcaaacg tttaatggag caagaaattc cagaagttta
     7681 tgatggaact gttgaaatca tgagcgtggc tcgtgaagca ggtgaccgta cgaaggttgc
     7741 tgttcgtagc cacaatccaa acgtggatgc tatcggtaca atcgttggac gtggtggtgc
     7801 taatatcaag aagattacta gcaaattcca cccagctcgt tacgatgcta aaaatgaccg
     7861 catggtacca atcgaagaaa atatcgatgt tatcgagtgg gtagcagatc cagctgaatt
     7921 tatctacaat gccatcgctc ctgctgaggt tgaccaagtt atctttgatg aaaacgacag
     7981 caaacgtgcc ttggtggttg ttccagataa caagctttct cttgccattg gtcgtcgtgg
     8041 acaaaacgtg cgcttggcgg ctcacttgac tggttaccgt atcgatatca agtctgctag
     8101 cgaatttgaa gccatggaag acgctgcttc agtagagttg gaagtagaaa acgatactgt
     8161 agaagaataa aagctgctag aggagggaaa gatgaaaaca agaaaaatcc ctttgcgcaa
     8221 gtctgttgtg tctaacgaag tgattgataa gcgtgatttg ctccgcattg tcaagaacaa
     8281 ggaaggacaa gtctttattg atcctacggg caaggccaat ggccgcggcg cttatatcaa
     8341 actagacaat gcagaagccc tagaggcgaa aaagaagaag gtctttaacc gcagctttag
     8401 catggaagtg gaagaaagct tttatgacga gttgatcgct tatgtggatc acaaagtgaa
     8461 aagaagagag ttgggacttg aataagcaaa agataagtaa tctcttgggg cttgctcagc
     8521 gagcagggcg catcatatcg ggtgaagaat tggtggtcaa ggccattcaa gacggcaagg
     8581 ccaagttggt ctttctagct catgatgctg gacccaatct gaccaagaag attcaagata
     8641 aaagtcatta ttatcaagta gaaattgtaa ccgtgttttc aacactggaa ttaagcatag
     8701 cagtcgggaa atcgagaaag gttttggctg taacagatgc tggatttaca aagaaaatga
     8761 ggtctcttat ggaatagaag aggaggacat gatttgtcta agaaaagatt gtacgaaatc
     8821 gcaaaagaac ttggaaaaga aagtaaagaa gttgtagcgc gtgcaaaaga gttgggcttg
     8881 gatgtgaaaa gccactcatc aagtgtggaa gaagctgtcg ctgcaaaaat tgctgccagc
     8941 tttaagcctg cagctgctcc gaaagtagaa gcaaaacctg cagcaccaaa agtaagtgca
     9001 gaaaagaaag ccgaaaaatc tgagccagct aaaccagctg tagctaagga agaggcaaaa
     9061 ccggctgagc cagttgctcc gaaaacagaa aaagtagcag tgaaaccgca aagtcgtaat
     9121 ttcaaggctg agcgtgaagc ccgtgctaaa gagcaggcag aacgacgcaa gcaaaataag
     9181 ggcaataacc gtgaccaaca acaaaacgga aaccgtcaga aaaacgacgg ccgtaatggt
     9241 ggaaaacaag gtcaaagcaa ccgcgacaat cgtcgcttta atgaccaagc taagaagcag
     9301 caaggtcagc aaaaacgtag aaatgagcgc cgtcagcaag aggataaacg ttcaaatcaa
     9361 gcggctccac gtattgactt taaagcccgt gcagcagccc taaaagcaga gcaaaatgca
     9421 gagtacgctc gttcaagtga ggaacgcttc aagcagtatc aggctgctaa agaagccttg
     9481 gctcaagcta acaaacgcaa ggaaccagag gaaatctttg aagaagcggc taagttagct
     9541 gaacaagcac agcaagttca agcagtggtt gaagtcgtcc ctgagaaaaa agaacctgca
     9601 gtggatacac gtcgtaaaaa acaagctcga ccagacaaaa atcgtgacga ttatgatcat
     9661 gaagaagatg gtcctagaaa acaacaaaag aatcgaagta gtcaaaatca agtgagaaat
     9721 caaaagaata gtaactggaa taacaacaaa aagaacaaaa aaggcaataa caagaacaac
     9781 cgtaatcaga ctccaaaacc tgttacggag cgtaaattcc atgaattgcc aacagaattt
     9841 gaatatacag atggtatgac cgttgcggaa atcgcaaaac gtatcaaacg tgaaccagct
     9901 gaaattgtta agaaactttt catgatgggt gtcatggcca cacaaaacca atccttggat
     9961 ggggaaacaa ttgaactcct catggtggat tacggtatcg aagccaaaca aaaggttgaa
    10021 gtggataatg ctgacatcga acgtttcttt gtcgaagatg gttatctcaa tgaagatgaa
    10081 ttggttgagc gtccaccagt tgttactatc atgggacacg ttgaccacgg taaaacaacc
    10141 cttttggata ctcttcgtaa ctcacgtgtt gcgacaggtg aagcaggtgg tattactcag
    10201 catatcggtg cctaccaaat cgtggaaaat ggtaagaaga ttaccttcct tgatacacca
    10261 ggacacgcgg cctttacatc aatgcgtgcg cgtggtgctt ctgttaccga tattacgatc
    10321 ttggtcgtag cggcagatga cggggttatg cctcagacta ttgaagccat caaccactca
    10381 aaagcagcta acgttccaat catcgtagct attaacaaga ttgataaacc aggtgctaac
    10441 ccagaacgcg ttatcggtga attggcagag catggtgtga tgtcaaccgc ttggggtgga
    10501 gattctgaat ttgttgaaat ctcagctaaa ttcaaccaaa atatcgaaga attgttggaa
    10561 acagtccttc ttgtagctga aatccaagaa ctcaaggcag acccaacagt gcgtgcaatc
    10621 ggtacggtta tcgaagcgcg cttggataaa ggaaaaggtg cggtcgcaac ccttcttgta
    10681 caacaaggta ccttgaatgt tcaagatcca atcgttgtcg gaaatacctt cggtcgtgtc
    10741 cgtgctatga ccaacgacct tggtcgtcgt gttaaagttg ctggaccatc aacaccagtc
    10801 tctatcacag gtttgaacga agcaccgatg gcgggtgacc actttgccgt ttacgaggat
    10861 gaaaaatctg cgcgtgcagc aggtgaagag cgtgccaaac gtgccctcat gaaacaacgt
    10921 caagctaccc aacgtgttag ccttgaaaac ctctttgata cccttaaagc tggggaactc
    10981 aaatctgtta atgttatcat caaggctgat gtacaaggtt ctgttgaagc cctttctgcc
    11041 tcacttcaaa agattgacgt ggaaggtgtc aaagtgacta tcgtccactc agcggtcggt
    11101 gctatcaacg aatcagacgt gacccttgcc gaagcttcaa atgcctttat cgttggtttc
    11161 aacgtacgcc ctacaccaca agctcgtcaa caagcagaag ctgacgatgt ggaaatccgt
    11221 cttcacagca ttatctacaa ggttatcgaa gagatggaag aagctatgaa agggatgctt
    11281 gatccagaat ttgaagaaaa agttattggt gaagcggtta tccgtgaaac cttcaaggtg
    11341 tctaaagtgg gaactatcgg tggatttatg gttatcaacg gtaaggttgc ccgtgactct
    11401 aaagtccgtg ttatccgtga tggtgtcgtt atctatgatg gcgaactcgc aagcttgaaa
    11461 cactacaaag acgacgtgaa agaagtgaca aacggtcgtg aaggtggatt gatgatcgac
    11521 ggctacaatg atattaagat ggatgatgtg attgaggcgt atgtcatgga agaaatcaag
    11581 agataagatt ttttgctcct ttcttaggtg gtgagggacg caagcaaacc gatggtttca
    11641 ttgcttattt ttgagcctag ggtctcaaaa atcccctgtg atgggactga taaatcagtt
    11701 ccatcacttt caccacggcg aaagaagcag atgacttcaa attgaacttc gtttcaattt
    11761 aaactgaaaa tcaagaagtt taaaatagct aggtctgctg gcctagcttt tggttcaaag
    11821 tagagaaagg aatatcatgg caaatcattt ccgtacagat cgtgtgggca tggaaatcaa
    11881 gcgtgaagtc aatgagattt tgcaaaagaa agtccgtgat ccacgtgtcc aaggtgtgac
    11941 catcacagat gttcagatgc tgggtgactt gtctgttgcc aaggtttatt acaccatttt
    12001 gagtaacctt gcttcggata accaaaaagc ccaaatcggg cttgaaaaag caactggtac
    12061 catcaaacgt gaacttggtc gcaatttgaa attgtacaaa atcccagatt tgaccttcgt
    12121 caaagacgag tccatcgagt atggaaacaa gattgacgag atgctacgca atctggataa
    12181 gaactaaaga agaggggttg cccctctttt ttggtggagg aaaataggtt gaatttgaaa
    12241 tggaaaaata ttcttttaaa atatattgaa actagaatag tacgc
//
LOCUS       DAVLBE010000054        11900 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.054, whole genome shotgun sequence.
ACCESSION   DAVLBE010000054 DAVLBE010000000
VERSION     DAVLBE010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11900)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11900)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11900
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.054"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            161..814
                     /locus_tag="VXB91_001644"
     CDS             161..814
                     /locus_tag="VXB91_001644"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HEV0471060.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGIIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTAWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR"
     gene            824..1288
                     /locus_tag="VXB91_001645"
     CDS             824..1288
                     /locus_tag="VXB91_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEV0471061.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECAAREILEETGLKAKPVLKGVITFPEFTPDLDWYTYVFKVTEFEGDLIDCNEGT
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            1301..2569
                     /locus_tag="VXB91_001646"
     CDS             1301..2569
                     /locus_tag="VXB91_001646"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HEV0471062.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIAPEITEEGAETI
                     DATGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAAGFSDDGIPLESSKIV
                     KEAMEEAKKFNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALLLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLS
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFEAGYLAENGPADITIFDAKADRFVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            2583..2843
                     /locus_tag="VXB91_001647"
     CDS             2583..2843
                     /locus_tag="VXB91_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0471063.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            2854..4215
                     /gene="pdrM"
                     /locus_tag="VXB91_001648"
     CDS             2854..4215
                     /gene="pdrM"
                     /locus_tag="VXB91_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HEV0471064.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPIILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDNIKEGVRLGLPIGGTVFAEVAIFSVVGLIMAKFSSLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTVRFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKC"
     gene            4369..5337
                     /locus_tag="VXB91_001649"
     CDS             4369..5337
                     /locus_tag="VXB91_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HEV0471065.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGPVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESAFEDIYAD"
     gene            5353..6345
                     /locus_tag="VXB91_001650"
     CDS             5353..6345
                     /locus_tag="VXB91_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HEV0471066.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFGPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLL
                     KSSIRDNNSVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEGISVEIVDPRTLVPLDKDIIINSVKKTGKVVLVNDAHKTSGYIGEIS
                     AIISESEAFDYLDAPIRRCAGEDVPMPYAQNLENAMIPTVESIKDAIRKTYNKE"
     gene            6563..7606
                     /locus_tag="VXB91_001651"
     CDS             6563..7606
                     /locus_tag="VXB91_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HEV0471067.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGKIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     KVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGVQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            7670..9355
                     /gene="lpdA"
                     /locus_tag="VXB91_001652"
     CDS             7670..9355
                     /gene="lpdA"
                     /locus_tag="VXB91_001652"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HEV0471068.1"
                     /translation="MPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKVSMELEA
                     EEDGYLIAILKGDGETVPVTEVIGYLGEERENIPTAGAASPEASSVPVASTSNDDDKS
                     DDAFDIVVIGGGPAGYVAAIKAAQFGGKVALVEKSELGGTCLNRGCIPTKTYLHNAEI
                     IENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVTVHKGIGT
                     ITKDKNVLVNGSELLETKKIILAGGSKVSKINVPGMESPLVMTSDDILEMNEVPESLV
                     IIGGGVVGIELGQAFMTFGSKVTVIEMMDRIVPAMDVEVSKNLRLILERKGMTILTGT
                     KLQEIIEENGQLRIKVEGKDDIIASKALLSIGRMPDLEGIGEVEFELDRGCIKVNEYM
                     ETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAVAKLNLTPAAIYTLPEVA
                     AVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVIADKKYGEILGVHIIGPA
                     AAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKKK"
     gene            9419..10408
                     /locus_tag="VXB91_001653"
     CDS             9419..10408
                     /locus_tag="VXB91_001653"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEV0471069.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFS
                     EEELAEINRIKDTKFGTWDWNYGKSPEFNVRRGIKFTSGKVEVFANVTESKIQDIKIY
                     GDFFGIEDVAAVEDVLRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG"
     gene            complement(10473..11543)
                     /gene="xerS"
                     /locus_tag="VXB91_001654"
     CDS             complement(10473..11543)
                     /gene="xerS"
                     /locus_tag="VXB91_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HEV0471070.1"
                     /translation="MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETEGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLD
                     LRDLNLKMMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVNDEQKNALDSL"
BASE COUNT         3535 a         2215 c         2664 g         3486 t
ORIGIN      
        1 taaaaagtaa ttataaaaaa tagccagtct ttataaactg tattcacgta ttcaaatcgt
       61 atatatagtc gatttattaa atctttagat aaactgtaaa aagtggtttc catagccact
      121 ttttgctata atagaggcag taaaaatgaa ggagtcggct atggaacact cgtcttggca
      181 tgctttgatt aaggcgcaat tacctgaggg ttatttcggg aaaatcaatc agtttatgga
      241 gcaggtctat tctcagggga ttatttatcc acccaaggaa aaggtttttc aggctctctt
      301 gacaacactg cttgaagaag ttaaggtggt aattctaggg caagacccct atcacggacc
      361 aggtcaagcg cagggcttga gtttttctgt acctgactct atcccagctc caccatcctt
      421 gcaaaatatc ttgaaagaat tgtcagatga tatcggagtt aagaaatctc atgatttgac
      481 agcttgggct gagcaaggag tcttgcttct taatgcttgt ttgactgttc ctgctggaca
      541 ggccaatggt catgctggtc aaatctggga gccttttact gatgctgtga ttcaggtggt
      601 caatcatcta gatagaccag tcgtttttgt actctgggga gcttatgcac gtaagaagaa
      661 ggcattagtt accaatcctc atcacttgat tatcgaatca gcccatccaa gtcctttgtc
      721 ggtttataga ggattttggg gttccaagcc cttttccaag gccaatgcat tcttaaaaga
      781 gacaggacaa gagccaatcg attggcttag ataaggagaa aatatgcctc agttagcgac
      841 gatttgctac attgataatg ggaaagaact gctcatgctc catcgtaata agaaacccaa
      901 tgatgtccat gaagggaaat ggattggtgt gggtggtaag ctagagagag gagagacgcc
      961 ccaggaatgc gcggcgcgtg aaatccttga agaaacaggg ctcaaagcca agccagttct
     1021 aaaaggtgtc atcacttttc ctgaatttac accagattta gactggtaca cctatgtttt
     1081 taaggtgacg gagtttgagg gcgacttgat tgactgcaat gaggggacgc tagaatgggt
     1141 tccctatgat gaggttttga gcaagccgac ttgggaaggt gaccacacct ttgttgagtg
     1201 gcttttagag gataaaccct tcttttcagc caagtttgtt tatgatgggg ataaattgtt
     1261 ggatacccaa gttgatttct atgaataaag gagaaagcag atgctactaa tcaaaaatgg
     1321 tcgtgtaatg gatcccaagt ctggtttgga tcaagtttgt gatgtcttag ttcaagatgg
     1381 gaaaattatc aaaattgcgc ctgagatcac ggaagaagga gcagaaacga ttgatgctac
     1441 tggtcttgtg gttgctcctg gtttggtcga tattcatgtg catttccgtg aacctggtca
     1501 aacacataaa gaagacattc atactggtgc cctggcagcc gctgcaggtg gttttactac
     1561 tgtcgtcatg atggctaata ccagtccaac catttcagac gtggagactt tgcaagcagt
     1621 tctccagtca gctgccaaag agaagattaa tgtcaagaca gttgcgacca ttactaaaaa
     1681 ctttaatggt aaaaacttga ctgactttaa ggcgctctta gaagctggtg cggctggttt
     1741 ctctgatgac ggtattccgc ttgagagcag taagattgtc aaggaagcca tggaggaagc
     1801 caaaaaattc aataccttta tcagccttca tgaggaagat ccaggtttga acggtgttct
     1861 tggctttaat gaaaatattg ctagagaaca tttccatatc tgcggtgcta ctggagtggc
     1921 tgagtacgct atgatggcgc gtgatgtcat gattgcctat gcaactaaag cccatgttca
     1981 catccagcat ttgtctaagg aagaaagtgt taaagtagtg gagtttgctc aggggttagg
     2041 tgcagaagtc acagcagaag tagcgccaca gcatttctct aagacagaag cacttctttt
     2101 aacacaaggt agcaatgcta agatgaatcc accgcttcgt ttggaatcag accgtcgtgc
     2161 cgttatcgaa ggtctcaaat caggtgtcat cacagttatt gcgactgacc acgcgcctca
     2221 tcatgtagat gaaaaaaatg ttgaggatat taccaaagcg ccatctggta tgactggctt
     2281 agaaacatcc ctgtctctca gcttgaccta tttagtagaa gctggtgagt tgagcttgat
     2341 ggaattactt gaaaaaatga catacaaccc agccaagctt tacaactttg aagcaggtta
     2401 cttggctgag aatggtccag cagatatcac tatttttgat gccaaggctg accgctttgt
     2461 ggactcccat tttgcttcca aagcagctaa ttcaccattc atcggtgaaa ccttaaaagg
     2521 gcaggttaaa tataccatct gtaagggaca aatcgtctat caagcttgat aggagttaga
     2581 atatgaatta ttttcgaaaa cgtagggaga gacaagcgaa atctaatagt ggaatttact
     2641 gtcccgcagc taatcgttcc aaaattcaat atgaaactaa agaaaaagct gaccatgcgg
     2701 ttcaatatga taacggaggt ttagttagaa gctattattg tcgtacatgt gcgtgttggc
     2761 atactacttc aaaatctaat aaacctccgc taagtttgaa aaactatggt ctgaaactct
     2821 ttggtttaga taaatcagaa tagaaagaga agtatgtata agacaaagtg tttacgagag
     2881 aagttagtat tatttttaaa aattttcttc ccaatcctga tctaccaatt tgccaattat
     2941 tctgcctctt ttgttgatac tgcaatgaca ggtcaataca acactatgga cttggctggt
     3001 gtatctatgg caaccagtat ctggaatcct ttctttacat ttctaacagg gattgtgtca
     3061 gctttggtgc ctatcattgg tcaccatctt ggtcgaggca aaaaggaaga agttgcgtct
     3121 gatttttacc aatttattta tttggccttg ggcctatctg tggtcttgct ggggatggta
     3181 cttttcttgg caccaataat cttgaatcat attgggttag aagcagcagt agcggcagta
     3241 gcggttcgct atctttggtt tttatctatc gggattatcc ccttgttgct ctttagcgtc
     3301 attcgttcct tgctggattc gctgggcttg accaaactgt ccatgtacct catgcttttg
     3361 ttactccctc tcaatagcgg atttaactat ctcttgattt acggtgcctt tggtgttcca
     3421 gaactgggag gggctggtgc tggtttagga acatccttgg cctactgggt cttgcttggg
     3481 atttctgttc tggttttatt taaacaggag aagctcaaag ccttacacct tgagaaacga
     3541 attccactta atatggataa cattaaggaa ggagttcgtt taggtctgcc tattggggga
     3601 actgtcttcg cggaagtggc tatcttttca gtggttggct tgattatggc taagttttcg
     3661 tccttgatta tagctagtca ccagtcagct atgaactttt caagtcttat gtacgccttt
     3721 cctatgagta tctcatcggc tatggctatt gtcgtttcct atgaagtggg agccaagcga
     3781 tttgatgatg cgaaaaccta tattggtcta ggaagatgga ctgctctcat ttttgcggcc
     3841 ttcaccttaa ccttccttta catttttagg ggaaatgtgg ccagtcttta tggtaacgac
     3901 ccaaaattta tcgatttgac agtgcgtttt ttaacttata gtcttttctt ccagttagca
     3961 gatacctttg cggcgccgct tcagggaatt ttgcgggggt ataaggatac agttattcct
     4021 ttttaccttg gtttgcttgg ttattggggc gtagcaatcc ctgtggctac gctatttgat
     4081 tccctaacag attttggagc ttattcttac tggatcggct tgattattag tttgattgtg
     4141 agcggggcgc tctaccgttg gcgtttaact gtgattatga agagatttga atctttagca
     4201 aaatccaaat gctaaaaagt ttgtgaaaaa atattcttga caagaaaatc ccttgttttc
     4261 acggggtttt cttttttatt ttgtgaaatt tcttttagaa aaactttgac agtatttgcc
     4321 aaaagcggta aaatagtaag gtaagaagaa agttagaaag gcaagaagat gtcaacttta
     4381 gataaaaatc ttttgctaga aatgttccgt aagatggaag aaatccgtcg catggactta
     4441 aaaattgcac aattagtaaa gaaagggaaa gtgccaggaa tgacgcactt ttctgttggt
     4501 gaagaggcag ctaacgtggg ggctatgtta gctctcaatc cagatgatct gattacctca
     4561 aaccaccgtg gacacgggca agctattgct aaagggattg acctcaacgg aatgatggct
     4621 gaaatccttg gtaaatacac tggaacctgt aaagggaaag gtggatctat gcatatcgct
     4681 gaccttgatg ctgggaacct tggtgccaat ggtatcgtag gtggtggtat ggggatcgct
     4741 gtcggtgcag ccctcagtca gcaaatgcaa aataccggta aaatcgttgt ctgcttcttt
     4801 ggagatggtg cgaccaatga aggtgttttc cacgaagcag tgaacatggc ttctatctgg
     4861 aacctgccag tcattttcta ttgcattaac aacggttacg gtatctctgc ggatatcaag
     4921 aaaatgacca atatagaaca tatccatcaa cgtagcgccg cttatggaat tcctggaatg
     4981 ttcatcgaag acggtaacaa tgtcatcgat gtctatgaag gatttcagaa agctgtggac
     5041 catgttcgca gtggcaatgg tccagtcttg attgaaagtg taacttatcg ctggctcggt
     5101 cactcatcat ctgaccctgg taaatatcgt acgcgtgaag aagtggaatt gtggaaacaa
     5161 aaagatccaa tcgaaaacct ccgcaattac cttattgaaa ataacattgc aagtgccgaa
     5221 gaattggaag aaatccaagc gcaagtaaag gaagcagtag aagcttctgt taaatttgca
     5281 gaggaaagcc cattcccacc gcttgaatca gcctttgaag atatttacgc agactaagga
     5341 gaaagagata aaatggaaac aaaaacaatg tccttccgtg acaccattat ccttgctatg
     5401 tctgaggaaa tgcgtcgcga tgaaaatgtg ttcttgatgg gagaagacgt cggtgtcttc
     5461 ggaggagact tcggtacttc tgttggaatg cttgaagaat ttggtccaga acgtgtccgt
     5521 gactgtccga tttctgaagc tgccatctct ggagcagcag caggagcagc catgacagga
     5581 cttcgtccaa tcgtcgatat gaccttcatg gacttctctg ttattgccat ggacaatatc
     5641 gtcaaccaag ctgctaaaac acgttacatg tttggtggta aaggtcaggt tccaatgact
     5701 gttcgttgtg cagctggtaa cggagttggc tctgccgccc agcactcaca atctctagag
     5761 tcttggttta ctcacattcc aggacttaag gttgtggcac ctggaacacc tgcggacatg
     5821 aaaggcctgc ttaagtcttc tatccgtgat aacaactcag ttattatact tgagtacaag
     5881 tcagaattta accaaaaagg ggaagtgcca gttgatccag actacacaat tccacttggg
     5941 gttggtgaaa tcaaacgcca aggaacggat gtaacagttg ttacttatgg aaaaatgctt
     6001 cgccgtgtgg ttcaagctgc tgaagaatta gcagaagaag gaatttcagt tgaaattgtt
     6061 gacccacgta cccttgttcc gcttgataag gatatcatca taaactcagt gaagaaaact
     6121 ggtaaggttg ttctggtcaa cgatgcccac aaaacaagcg gctatatcgg tgaaatttca
     6181 gctattattt cagaatcaga agcatttgac tatctagatg caccaatccg ccgttgtgca
     6241 ggagaagatg tgccgatgcc ttatgcacaa aacctagaaa atgcaatgat tccaacagtt
     6301 gaaagtatca aagatgcaat ccgaaaaact tataacaaag aatagggtta cataagataa
     6361 gttatgtaaa taaaataaag ctgacgagaa actttgtatc ttttaggtgc agagctcttc
     6421 gtcattaata tcttagatta gagcacgggc taaaagatcg gaaaaaagat aaatctcctt
     6481 ggcttcatcg aagccatcgt cgatttccta tttttcagtc gcttttgacg ccctttgtat
     6541 cataaataga attggagagg tcatggctga tgacaagcta agagcgactc ctgcagctag
     6601 aaagttagcg gatgatttag ggataaacct ctacgacgtt tctggctcag gtgcaaacgg
     6661 tcgtgtccac aaagaagacg tggaaactta taaagacaca aacgtggttc gcatttcgcc
     6721 acttgcaaaa cgaattgccc tcgaacataa cattgcttgg caggaaatcc aaggaaccgg
     6781 tcatcgtggt aaaatcatga agaaggatgt tttggccctg cttcctgaaa atatcgaaaa
     6841 cgatagcatc aaatctcctg ctcagattga aaaagtggaa gaagtccctg ataacgtaac
     6901 accatatggt aaaatcgagc gtattccaat gacaccaatg cgtaaggtta ttgcccaacg
     6961 catggttgaa tcttacttga ctgcgccaac cttcaccctc aactatgaag ttgatatgac
     7021 tgaaatgttg gctcttcgta agaaggttct tgagccaatc atggaagcaa ctgggaagaa
     7081 gactactgta acagaccttc tttcgcttgc agttgttaag actcttatga aacacccata
     7141 catcaacgct tcattgacag aagatggcaa gactattatc actcacaact atgtcaatct
     7201 tgccatggca gttgggatgg ataatggatt gatgacacct gttgtttaca atgctgagaa
     7261 gatgagtctt tcagaactgg ttgtagcctt taaggatgtt attggccgta ccttggatgg
     7321 taaattggct ccaagtgagt tacaaaattc aacattcaca atcagtaatt tgggaatgtt
     7381 tggtgttcag tcctttggtc cgattattaa ccaacccaac tcagctatcc ttggtgtcag
     7441 ttcgacaatc gagaagccag ttgtcgtcaa tggtgaaatt gtgattcgcc caatcatgag
     7501 tttaggatta accattgacc accgtgtcgt agatggtatg gctggtgcta agtttatgaa
     7561 ggacttgaaa gagttgattg aaacgccaat ctcaatgtta atttaagagc aagagtattc
     7621 atttttaaga tatagataaa ggaaggaaga catggcctta gaagtaatta tgccaaaagc
     7681 cggcgtggat atgacagaag gacaaatcgt ccaatggaat aaaaaagtcg gagaatttgt
     7741 aaaagaagga gaaatccttt tggaaatcat gactgataaa gtcagcatgg aattggaagc
     7801 cgaagaagat gggtacttga ttgccattct caaaggagat ggtgaaactg tccctgtaac
     7861 ggaagttatc ggttaccttg gtgaagaaag ggaaaacatc ccaacagctg gagcagcatc
     7921 gccagaagct agctctgtac ctgtagcaag tacctcaaac gatgatgata agagcgatga
     7981 tgcttttgat atcgttgtga ttggtggagg tcctgctggt tatgttgcag ccattaaagc
     8041 tgcccaattc ggcggtaagg ttgcccttgt tgagaaatct gaacttggtg gaacctgctt
     8101 aaaccgtgga tgtattccaa ccaagaccta ccttcataac gctgaaatta ttgaaaatat
     8161 cggtcatgct gcaaatcgtg gtatcgtgat tgaaaatcct aacttcactg ttgatatgga
     8221 aaaactttta gaaactaaat ctaaagttgt taatactctt gttggtggtg ttgcaggact
     8281 tcttcgtagc tacggagtta ctgttcataa aggaattggt acaatcacta aagacaagaa
     8341 cgtcttggta aatggttctg aattgcttga aaccaagaaa atcattcttg ctggtggttc
     8401 aaaagtcagc aagatcaacg tccctggtat ggaatctcca cttgtcatga ctagtgatga
     8461 cattcttgaa atgaacgaag tgccagaaag ccttgttatc atcggtggtg gagttgtcgg
     8521 tatcgaactc ggtcaggcct tcatgacatt tggttcaaaa gtgactgtta tcgaaatgat
     8581 ggaccgtata gttccagcta tggatgtgga agtttctaag aaccttcgct tgattcttga
     8641 gcgtaaagga atgaccatct tgactggtac taaactgcaa gaaatcattg aggaaaatgg
     8701 tcaacttcgt atcaaggttg aaggaaaaga cgatatcatc gcaagcaaag ctcttctttc
     8761 aattggtcgt atgccagacc ttgaaggtat tggagaggtt gagtttgaat tggatcgtgg
     8821 ttgtatcaag gtcaacgaat acatggaaac ttcagttcca ggcatttatg caccaggtga
     8881 catcaacggt actaagatgt tggctcacgc agctttccgc atgggtgaag tttccgctga
     8941 aaatgccctt aaaggaaatc atgcagttgc caaattgaat ttgactcctg cagccatcta
     9001 cactctccct gaagtagcag cagtaggttt gacagaagaa caagcccgtg agaaatacga
     9061 tgttgccatc ggtaagttta actttgctgc taacggtcgt gctattgcat ctgacgcagc
     9121 tcaaggtttc gtaaaagtta tcgctgataa gaaatacgga gaaatccttg gtgtacacat
     9181 tattggtcct gcagccgcag aattaataaa cgaagcatca agcatcatcg aaatggaaat
     9241 cactgttgag gaaatgctga agaccatcca cgggcaccca acttactctg aagtgatgta
     9301 cgaagcgttt gcagatgttc taggaatggc catccattca cctaagaaaa aataaaacga
     9361 agatagatta gactggaagg ttatttccag tttctatcat ataaagtaaa gggatatcat
     9421 gaaatacatt atcaatcatt caaatgacac tgcttttaat attgccttgg aagaatacgc
     9481 ctttaaacac cttttggatg aggatcaaat cttcctactt tggattaaca agccatctat
     9541 cattgttggt cgtcaccaga acactatcga agaaatcaac cgtgattatg ttcgcgaaaa
     9601 tggtattgag gtagttcgcc gtattagtgg tggtggagct gtttaccacg atttaaataa
     9661 cctcaactac acgatcatct ccaaagaaga tgaaaataag gcatttgact tcaagagctt
     9721 ctcaactccg gttatcaata ccctggctca acttggggtt aaagctgagt tcacaggtcg
     9781 taatgacctt gagattgatg gtaagaagtt ctgtggcaat gcccaagcct atatcaacgg
     9841 ccgtatcatg caccacggtt gcttgctctt tgacgttgat ttgtcagtcc tcgcaaatgc
     9901 ccttaaggtt tcaaaagata aatttgaatc aaaaggtgtg aaatccgtcc gtgcccgtgt
     9961 aaccaatatt atcaatgaat taccaaaaaa aatcacagtc gaaaaattcc gtgatttact
    10021 cttggaatac atgaaaaaag agtacccaga gatgactgaa tacgtctttt cagaagaaga
    10081 attggccgaa atcaatcgca tcaaggatac taagtttgga acttgggact ggaactatgg
    10141 taaatcacct gaatttaacg tccgtcgtgg aatcaaattc actagtggta aggttgaagt
    10201 ctttgctaac gttactgaat caaaaatcca agacatcaag atttatggtg acttctttgg
    10261 tattgaagac gttgctgcag tagaagatgt ccttcgtggg gtgaaatacg aacgcgaaga
    10321 tgttcttaag gcgctaaaaa ccattgatat cacacgctac ttcgctggta ttagccgtga
    10381 agaaatcgct gaagcggtag ttggataaat caaaaagaag ttggccaact tctttttttg
    10441 atatttattt acataattta aaatacgtaa aatcataaac tatccagagc attcttttgt
    10501 tcatcattaa caatatgggt atagaggtca gtgacttgtg tgctggcatg tcctagttgg
    10561 tgactgacta aaacttgtga tttagtagca tcatagagcc tagttgctag tgtatggcgc
    10621 agtttatggg gtgttacacg tactttaaaa tcctctgagt atttagcaac cattttctca
    10681 acgctagaag catcgatacg attaggaaca cctctgtaga gagttaaaaa aagggctgta
    10741 tctgtttttt ccgttttata gcgttgattc cgaatggcca gataattctc taaataaggt
    10801 ttagcaaaag cagcgacatt gactgagtca cgtttgccac cttttcgagt aacatcaata
    10861 accatcattt ttagattgag atctcttaga tctagattaa cagcttcaga taagcgaaca
    10921 ccagatgcca agagaagggc aataatggct aaatctcgtt ctttattttt gttgaatgat
    10981 gagagagctc gatttgaaag ctgttgtggg tgctcttgat cgatataagt tagaaaacct
    11041 tctgtttcat cacctagaaa gagtttttgc ttgatatttt cagctctggc agcaagggtt
    11101 tctttctttt tcttggttga aacttttttc attacattac gatagaaata aggttccccc
    11161 tgatcgtttt caacctcctc ggttagatac ttgtaaagac tagaaagtgc tgataaggtt
    11221 cgattgatag ttgtctgtga aacaccttgt tttgttgtat tagcattcag caagggacgt
    11281 tcacgtagat aaaggataaa ggattccatg tctttcttag acatattttc caaaactgat
    11341 aaaggaatat cggatatttt atcagcgttt gaaataccag actccaaaac ccagctgaaa
    11401 aatcggtcat attccttaag gtattcgtac agggttgtaa aactgtaggg cacagccagt
    11461 ttagattggt agtattccag aacataccag ggcatgagtt gttttagttt gtcgattcgt
    11521 tccagtaaaa tctcacgttt catgtatttt ctccataatt aagtatacta gtagtatagc
    11581 atagacttgt atatttttca agaaaattat agtttttcag aaagatgtta taggagtttt
    11641 tcaaagtgat aaaaagactt agacctacaa acaaaacaga ataaggaaaa taataaaaat
    11701 ctcacccact aaacttctgt taatactaca taactgaaga gctatataag gagctatgag
    11761 atacaaaaca cattgtataa tagattgaaa ctagaatagt acatctggac ttctaaaaca
    11821 ttgctagaaa ttgatttgat tgtcctgatt gttttatcct atttctattt catttctcta
    11881 tataattgct attgttttct
//
LOCUS       DAVLBE010000055        11689 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.055, whole genome shotgun sequence.
ACCESSION   DAVLBE010000055 DAVLBE010000000
VERSION     DAVLBE010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11689)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11689)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11689
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.055"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            168..857
                     /locus_tag="VXB91_001655"
     CDS             168..857
                     /locus_tag="VXB91_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEV0471071.1"
                     /translation="METKKIKNLKGQIIVSCQALEGEPLYTPNGGVMPLLAKAAFQAG
                     AKGIRANSVRDISEIKEEVDLPIIGIIKRDYDGFEPFISATMKEIDELVSEGVDILAL
                     DCTNRSRPGYDNITDFIHDIKVKYPNQLLMADISTFEEGKVAAESGVDFVGTTLSGYT
                     PYSPKKDNPDFELAERLVKELDVPVIAEGRISTPEQARKMLDLGAYAVVVGGAITRPK
                     EIAQRFINVIK"
     gene            882..1799
                     /locus_tag="VXB91_001656"
     CDS             882..1799
                     /locus_tag="VXB91_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate lyase"
                     /protein_id="HEV0471072.1"
                     /translation="MKDLTKYKGVIPAFYACYDENGEISQERVKSLVQYFIDKGVKGI
                     YVNGSSGECIYQSVEDRKQIIEAVMEVAKGKLTVINHVACNNTKDSIELAKHSESVGV
                     DAIAAIPPIYFKLPEYSIAAYWNAMSEAAPNTDFIIYNIPQLAGVALTGSLYATMRQN
                     PRVIGVKNSSMPVQDIQMFVAAGGEDYIVFNGPDEQYLGGRLMGAEAGIGGTYGVMPD
                     LFLKLESLIQERDLDTAKKLQYAINEVIYKMISGKANMYAVAKEVLRLNEKLDLGSVR
                     QPLEALAEGDLEVAKQAAELIQQARKEFL"
     gene            1827..3368
                     /locus_tag="VXB91_001657"
     CDS             1827..3368
                     /locus_tag="VXB91_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000537364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
                     /protein_id="HEV0471073.1"
                     /translation="MGTTGFTIIDLIILIVYLLAVLVAGIYFSKKEMKGKEFFKGDGS
                     VPWYVTSVSIFATMLSPISFLGLAGNSYAGSWILWFAQLGMVVAIPLTIRFILPIFAR
                     IDIDTAYDYLDKRFNSKALRIISALLFIIYQLGRMSIIMYLPSAGLSVLTGIDINILI
                     ILMGAIAIVYSYTGGLKSVLWTDFIQGVVLISGVVVALFVLMANIKGGFGAVAETLAN
                     GKFLAANEKLFDPNLLSNSIFLIVMGSGFTILSSYASSQDLVQRFTTTQNIKKLNKML
                     FTNGVLSLAIATVFYLIGTGLYVFYQVQNAGSAASNIPQDQIFMYFIAYQLPVGVTGL
                     ILAAIYAAAQSTVSTGLNSVATSWTLDIQDVISKNMSEDRRTKIAQFVSLAVGLFSIV
                     VSIIMAHSDIKSAYEWFNSFMGLVLGLLGGVFILGFVSKKANKQGAYAALIVSTIVMV
                     FIKYFLPPTAVSYWAYSLISISVSVVSGYIVSVLTENKVSAPKYTTIHDISEIKADSS
                     WEVRH"
     gene            3394..3852
                     /locus_tag="VXB91_001658"
     CDS             3394..3852
                     /locus_tag="VXB91_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEV0471074.1"
                     /translation="MIISEQSDFRRYASVNKHFSKVCDFLENTNLTDLVDGKIDIDGE
                     NVFANCMTYLADGVPGDIFETHKKYLDIHIVVENTEKMAVTSPVRAQSRVPFSEEKDI
                     AFYDSKDYQIVELLPGNMLVTFEEDLHQPKIHCNDETVKKLVIKVLNEEK"
     gene            3854..6076
                     /locus_tag="VXB91_001659"
     CDS             3854..6076
                     /locus_tag="VXB91_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exo-alpha-sialidase"
                     /protein_id="HEV0471075.1"
                     /translation="MKKNIKQYVTLGTVVVLSAFVANSVAAQETETSEVSTPELVQPV
                     APTTSISEVQHKSGNSSEVTVQPRTVETTVKDPSSTAEETPVLEKNNVTLTGGGENVT
                     NELKDKFTSGDFTVVIKYNQSSEKGLQALFGISNSKPGQQNSYVDVFLRDNGELGMEA
                     RDTSSNKNHLVTRPASVWGKYKQEAVTNTVAVVADSVKKTYSLYANGTKVVEKKVDNF
                     LNIKDIKGIDYYMLGGVKRAGKTAFGFNGTLENIKFFNSALDEETVKKMTTNAVTGHL
                     IYTANDTTGSNYFRIPVLYTFSNGRVFSSIDARYGGTHDFLNKINIATSYSDDNGKTW
                     TKPKLTLAFDDFAPAPLEWPRDVGGRDLQISGGATYIDSVIVEKNNKQVLMFADVMPA
                     GVSFREATRKDSGYKQIDGNYYLKLKKQGDTDYNYTIREHGTVYDDRTNRPTEFSVDK
                     NFGIKQNGNYLTVEQYSVSFENNKKTEYRNGTQVHMNIFYKDALFKVVPTNYIAYISS
                     NDHGESWSAPTLLPPIMGLNRNAPYLGPGRGIIESSTGRILIPSYTGKESAFIYSDDN
                     GASWKVKVVPLPSSWSAEAQFVELSPGVIQAYMRTNNGKIAYLTSKDAGTTWSAPEYL
                     KFVSNPSYGTQLSIINYSQLIDGKKAVILSTPNSTNGRKHGQISIGLINDDNTIDWRY
                     HHDVDYSNYGYSYSTLTELPNHEIGLMFEKFDSWSRNELHMKNVVPYITFKIEDLKKN
                     "
     gene            6116..7225
                     /locus_tag="VXB91_001660"
     CDS             6116..7225
                     /locus_tag="VXB91_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEV0471076.1"
                     /translation="MVNYGIVGAGYFGADLARSMNKIEDAKVVAVFDPNHGEEVAQEL
                     GSDVCASLDELVAREDIDCVIVASPSYLHREPVVKAAQHGKHVFCEKPIALSYEDCKA
                     MVDACKENNVIFMAGHIMNFFNGVHHAKELITQGKIGKVLYCHAARTGWEEQQPTVSW
                     KKLRSQSGGHLYHHIHELDCIQFIMGGLPEKATMVGGNVYHKGENFGDEDDMLIVNLE
                     YSDDRYAVLEYGNAFRWGEHYVLIQGTEGAIKLDLFNTGGTLRVKGEGESHFLVHETQ
                     EEDDDRTAIYTGRGMDGAIAYGKPGVRCPLWLQTCIDKEMEYLHDIIKGGEITEEYEK
                     LLNGVAALESIATADACTLSVKEDRKVSLSEITNA"
     gene            7382..8272
                     /locus_tag="VXB91_001661"
     CDS             7382..8272
                     /locus_tag="VXB91_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV0471077.1"
                     /translation="MKIIGIDIGGTTIKADLYDDFGTSLNQFKEIETIIDYDLGTNQI
                     LNQVCDLIGEYVLNYSIDGVGISTAGVVNANTGEIIYAGYTIPGYIGVNFTSEIEKRF
                     GLSTFVENDVNCAALGELWEGQAKDKKNVVMVTIGTGIGGSIIVNGQIVNGFNYTAGE
                     VGYIPVGNSDWQSKASTTALIHLYQKKSLKTNQTGRTFFTDLSSGDKVAKETFEIFVE
                     NLTKGLLTISYLLNPEILILGGGILAKKDILLPEIQSSLAKNAMDNRFLPKNVVAATL
                     GNEAGRIGAVKNFLDRISNK"
     gene            8297..8620
                     /locus_tag="VXB91_001662"
     CDS             8297..8620
                     /locus_tag="VXB91_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0471078.1"
                     /translation="MTNSVFSTMQDIENVATDIIKSYDNEIYTYKAVSQEELEKLEKS
                     YDEKSHEELISIESNLEMKQQNLIDEVNKTIKENDAKIQYISSSRRGEFVEKIIGRVV
                     EKYGY"
     gene            8610..10601
                     /locus_tag="VXB91_001663"
     CDS             8610..10601
                     /locus_tag="VXB91_001663"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HEV0471079.1"
                     /translation="MAISQMKRISLLFTKSSLDDVLKTIQELESVQFRDLKVQDNWSE
                     ALEKDEVVFSTIQISHTSNSHHGVIEGNDALNYLMNKQQHLEATVEKLQEYLPKENTF
                     KLLQQPPITTSYEELEKFGKANVAEGVLKKVNHQINRVHELERNIQSNNEEIERLIKW
                     EKLEIIPAHLEQFSFCRGKVGTIPRTVDNRLYNNFLENNIEVQEIFSNDREYGVVVFY
                     QSSCSIDFDEYLFEPFDYSRKELPKQRVVDLDQENMQLITEKENIIASLQDSKKNLID
                     LQWQIDYILSIYARQISKNNLLSTPHLVALEGWIEETRILYFIKVMDERFGHSIYIYE
                     SETLSDNQDEIPIKLTNHSLIEPFELLTEMYALPKYYEKDPTPVLAPFYFTFFGMMVA
                     DLGYGLLLFLGIMLALKIFHLPSVTKKFLKFFNILGVAVAIWGGIYGSFFGYELPFHL
                     ITTTSDVMTILVVSVVFGFITVFVGLLASGLQKVRMKKYAEAYNSGFAWCVILLGLLF
                     IAVGMLMPDIRPLFVLGKWVSIFNAVGILIASIIQAKSLSGIGSGLFNLYNISSYIGD
                     LVSFTRLMALGLSGASIASAFNLIVGLFPGTLAKLTIGLVLFILLHAINIFLSLLSGY
                     VHGARLIFVEFFGKFYEGGGKPFQPLKASEKYIKVITKN"
     gene            10617..11093
                     /locus_tag="VXB91_001664"
     CDS             10617..11093
                     /locus_tag="VXB91_001664"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HEV0471080.1"
                     /translation="MEHLATYFSTYGGAFFAALGIVLAVGLSGMGSAYGVGKAGQSAA
                     ALLKEQPEKFASALILQLLPGTQGLYGFVIGILIWLQLTPELPLEKGVAYFFVALPIA
                     IVGYFSAKHQGNVAVAGMQILAKRPKEFMKGAILAAMVETYAILAFVVSFILTLRV"
     gene            11127..>11689
                     /locus_tag="VXB91_001665"
     CDS             11127..>11689
                     /locus_tag="VXB91_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000067169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0471081.1"
                     /translation="MSNLENLRESVIEQAHEKGSMKLLDSKKKIDDEFEMQKSVIVKK
                     KEAEHERKLKELQQKYQIIFQQLKNKERQSTLVSKQKILKELFQSALIEMESWSADKE
                     MEFIYRILERYSQQEVIVTFGERTLAKFNLEQLEKLKFSFPNHLFSEQPISNESGLLI
                     SIGKIDDNYLYKTLIGSISKEESSSIA"
BASE COUNT         3941 a         1665 c         2328 g         3755 t
ORIGIN      
        1 gtgtattgaa tctataacag tacgccttaa atgctaaaat atttctataa attaatttaa
       61 ctttcctgat agggctgttc atatcttatt tcaattcact atataaataa aattgtagta
      121 gatgttattg aattagtaaa aaaaataaaa aaacggaggt tttctgaatg gaaactaaaa
      181 aaattaaaaa tttaaaaggt caaataattg tttcctgcca agcgttagaa ggagagccac
      241 tttatactcc aaatggagga gtgatgccgt tattagcaaa agccgccttt caagcaggcg
      301 ctaaaggtat tcgtgctaat tctgtccgcg atatttcaga aataaaagaa gaagttgact
      361 taccaattat aggtatcata aaaagagatt acgatggctt tgaacctttt atttcagcaa
      421 ctatgaaaga gattgatgaa ttagttagtg aaggagtaga cattttagct ttggattgta
      481 ctaatcgttc aagaccaggt tatgataata ttactgactt tattcatgat attaaagtca
      541 agtatccaaa ccaattatta atggctgata tttctacttt tgaagaaggg aaagtagctg
      601 ctgaatcggg agtagatttt gtgggtacga cattatctgg ttatacacca tatagcccta
      661 aaaaagataa tcctgatttt gagttagctg aaagattggt aaaagagctt gacgtaccag
      721 ttattgctga aggaagaata agtactccgg aacaagctag aaaaatgtta gatttaggtg
      781 cttacgcagt ggttgttgga ggagctatca ctcgtccaaa agaaattgct cagcgattta
      841 ttaatgtcat caaataaaaa acaatataaa ggagaaatct gatgaaagat ttaactaaat
      901 acaaaggcgt tattcctgca ttttatgctt gctatgatga aaatggtgaa attagccaag
      961 aacgtgtaaa atctctggtg caatatttca ttgacaaagg tgtaaaaggt atctatgtaa
     1021 atggttcttc aggtgaatgt atttaccaaa gtgtagaaga tcgtaaacaa attattgaag
     1081 ctgttatgga agttgctaaa ggtaaattaa cagttatcaa ccatgttgca tgtaataaca
     1141 cgaaagatag tattgaattg gcaaaacatt cagaaagtgt tggagtcgat gctattgctg
     1201 ctatcccacc tatttacttc aaattgccag aatattcaat tgcagcatat tggaatgcaa
     1261 tgagtgaagc tgcgccaaat acagatttta tcatttataa tattccacaa ttggcagggg
     1321 ttgcgttgac tggtagtttg tatgcaacaa tgcgtcaaaa tcctcgtgtg attggagtta
     1381 aaaattcttc tatgcctgta caagatattc aaatgtttgt agctgcaggt ggagaagatt
     1441 acattgtatt caatggtcca gatgaacaat atcttggtgg tcgcttgatg ggagcagaag
     1501 ctggtattgg tggtacttat ggcgttatgc cagatttgtt cttgaaattg gaaagtttga
     1561 ttcaagaacg agatttagat actgctaaaa aacttcaata tgctatcaat gaagttatct
     1621 ataagatgat atcaggtaag gcaaatatgt atgctgtagc aaaagaggtt ttgcgtctaa
     1681 atgaaaaact tgatttaggt tctgttcgtc aacccttaga agcattggca gaaggtgact
     1741 tggaagttgc aaaacaagca gcagaactta ttcaacaagc acgaaaagaa tttttataat
     1801 aaataaaatc aatatggaga tatgttatgg gcacaacagg atttacaata attgacttaa
     1861 ttatcttgat tgtttattta cttgcggtgt tggttgcagg tatctatttc tctaaaaaag
     1921 agatgaaagg aaaagagttc tttaaaggag atggttcggt tccttggtat gttacttcgg
     1981 tatccatttt tgccacaatg ctcagtccga tttccttctt gggactcgct ggtaactctt
     2041 atgcaggtag ctggatttta tggtttgctc aattagggat ggttgtagct attccactga
     2101 caattcgttt tatcttacct atctttgcac ggatagacat cgatacggca tatgattact
     2161 tggataaacg ttttaattct aaagcacttc gtattatttc agcactcttg tttattattt
     2221 atcaattggg acgtatgtct atcattatgt acctcccatc agctggttta tcagtattga
     2281 caggaattga catcaatatt ttgattattt tgatgggtgc aattgcaatt gtttattctt
     2341 atactggtgg tctaaaatcc gtattatgga cagactttat tcaaggtgtg gttctgatta
     2401 gtggtgtcgt tgtagcttta tttgtactga tggctaatat taaaggtggc tttggtgcag
     2461 tagcagaaac attagcaaac gggaaattcc ttgctgcaaa tgaaaaactt ttcgatccta
     2521 acttgctttc aaactccatc ttcttaattg tgatgggttc aggctttaca atcttgtctt
     2581 cctatgcttc atctcaagat ttggttcaac gttttactac aacacaaaat attaagaaac
     2641 ttaataaaat gttgttcaca aatggtgtct tgtcacttgc aattgcaaca gtcttttact
     2701 tgatcggtac aggcttgtac gtattctatc aagtacaaaa tgcaggtagt gcagctagca
     2761 atatccctca agaccaaatc tttatgtact ttattgcata ccagttacca gtaggtgtca
     2821 caggtttgat cttggcagcg atttatgcag cagctcaatc aactgtttca acaggtttga
     2881 actctgttgc aacttcatgg acattggata ttcaagatgt catttctaaa aatatgtcag
     2941 aggatcgtcg tacgaaaatt gcacaattcg tatctctagc agtaggttta ttctcaattg
     3001 ttgtttccat tatcatggct cattcagata ttaaatctgc atacgaatgg ttcaatagtt
     3061 tcatgggact tgtacttggt ctacttggtg gtgtattcat tcttggtttt gtttctaaaa
     3121 aagcaaataa acaaggtgct tatgcagcgc tgattgtatc aaccatcgtt atggtattta
     3181 ttaaatactt ccttcctcca acagctgtta gctactgggc atattcattg atttcaattt
     3241 ctgtatcagt agtttcaggt tatattgtat ctgttcttac tgaaaataaa gtatctgcac
     3301 ctaaatatac aacgattcat gatatttcag aaattaaagc ggattcaagt tgggaagttc
     3361 gtcactagtc actaatagaa aagagaaaat aatatgatta tttctgaaca atctgatttt
     3421 agacgatatg cttctgtcaa taaacatttt tcaaaagtct gtgatttttt agaaaataca
     3481 aatttgacag atttagttga tggaaaaatt gatattgacg gggaaaatgt ttttgcaaat
     3541 tgtatgactt atctagctga tggagttcca ggagatattt ttgaaactca taagaaatat
     3601 ttagatattc atattgttgt tgaaaataca gaaaaaatgg cagtaacttc cccagttcgt
     3661 gctcagtcac gtgtaccttt tagcgaagag aaggatattg ctttttacga tagcaaagac
     3721 tatcaaattg ttgaattgct tccagggaat atgttggtga cttttgaaga agatcttcac
     3781 caaccaaaga ttcattgcaa tgatgaaact gttaaaaaac ttgttatcaa agttttaaac
     3841 gaggaaaaat aaaatgaaaa aaaatattaa acaatatgta accttaggta ctgtagtggt
     3901 attatcagca tttgttgcta actcagttgc agctcaggag actgaaactt ctgaagtatc
     3961 aacaccagag ttggtgcaac ctgttgcacc aacgacttcg atttcggaag tacaacataa
     4021 atcgggtaac tcttcggaag ttactgtaca acctcgaaca gttgaaacta ctgttaagga
     4081 tccatcttct acagcggaag aaactcctgt cttagaaaaa aataatgtta ctttaacagg
     4141 gggcggagaa aatgttacta atgagttaaa ggataaattt actagcggtg actttactgt
     4201 agtgattaag tacaatcagt ctagtgagaa aggtttacaa gctctgtttg gaatatctaa
     4261 ttctaaaccc ggtcaacaaa atagttatgt agatgtgttc cttagagaca atggtgaatt
     4321 gggaatggaa gcgcgtgata cttcttccaa taaaaatcac ctagtaacca gacctgcttc
     4381 agtttggggt aagtacaaac aagaggccgt gacgaacact gttgcagtag tagcagattc
     4441 agtcaaaaaa acgtattctt tatatgcaaa tggtacaaaa gtagtagaaa agaaagtgga
     4501 taacttccta aacatcaagg atattaaagg tattgattac tatatgcttg ggggagtgaa
     4561 acgtgcagga aaaacggcgt ttggttttaa cggaacacta gaaaatatca aattctttaa
     4621 tagtgcattg gatgaagaaa ctgttaaaaa gatgacaaca aacgctgtta ctggacattt
     4681 aatttatacg gctaatgata caacaggttc taactatttc cgtattccag ttctgtatac
     4741 ttttagcaat ggtcgggttt tttcaagcat tgacgctcgt tacggtggaa ctcatgattt
     4801 cttgaataaa attaatattg ctacaagtta tagtgatgat aatggtaaga catggactaa
     4861 accaaaatta acattagcat tcgatgattt tgcgccagca ccattagaat ggcctcgtga
     4921 tgttggtgga cgtgacttac aaatcagcgg tggtgcaacc tatattgact ctgttattgt
     4981 tgaaaaaaat aacaaacaag tactcatgtt tgctgatgtt atgcctgctg gagtaagttt
     5041 tagagaagct actagaaaag attcaggtta taaacaaatt gatggtaatt attaccttaa
     5101 attaaagaaa caaggtgata ctgattataa ttatactatt cgtgagcatg gtactgtata
     5161 cgacgatcgt accaacagac caactgaatt ttcagtagat aaaaatttcg gtattaaaca
     5221 aaatggtaat tatttgacgg tagagcaata ttcggtttca tttgaaaata ataaaaagac
     5281 tgaatatcgt aatgggactc aagtccatat gaatatcttc tacaaagatg cattattcaa
     5341 agtagtgcca acgaactata ttgcatatat ttctagcaat gatcatggcg aatcttggtc
     5401 tgcaccaact ttattacctc ctataatggg acttaatcgg aatgcacctt atttgggtcc
     5461 tggacgtgga atcattgaaa gctcaactgg acgtattctt attccgtctt acactggtaa
     5521 agagtctgca ttcatttata gtgacgataa tggagcgtct tggaaagtta aagttgtgcc
     5581 acttccttct agttggtcag cagaagcaca atttgtagaa ttgagtccag gagtaattca
     5641 agcatacatg cgtacaaata atggtaaaat tgcatattta acaagtaaag atgcaggtac
     5701 tacttggagt gcgccggaat atttgaaatt tgtttcaaat ccaagttatg gaacacaatt
     5761 atcaatcatc aattatagtc aattgattga tggtaaaaag gctgtcattt taagtactcc
     5821 aaactccaca aatggtcgta aacacggaca aatttcgatt ggtctaatta atgatgataa
     5881 tacaattgat tggcgttatc atcacgatgt tgattatagt aactatggat actcatattc
     5941 aacattgaca gagttaccaa atcatgaaat tggattgatg tttgaaaaat ttgattcatg
     6001 gtctcgtaat gaacttcata tgaaaaatgt tgtaccatat ataacattta agattgaaga
     6061 tttgaaaaag aattaaagct gaaatttaaa aatatataga aagaggataa aaattatggt
     6121 aaattacggt attgttggag ctggatattt tggagctgat ttggctcgct caatgaacaa
     6181 aattgaagat gcaaaagtgg ttgcggtatt tgacccaaat catggagaag aagttgctca
     6241 agagttggga tcagatgttt gtgcaagttt agatgaactt gtagcacgtg aagatattga
     6301 ttgtgtgatc gtagcttcac ctagctacct tcaccgtgaa cctgttgtga aagctgctca
     6361 acatggcaaa cacgtatttt gtgaaaagcc aattgcattg tcttatgaag attgtaaagc
     6421 catggttgac gcatgtaaag aaaataatgt tatctttatg gctggtcaca tcatgaactt
     6481 ctttaatggt gtacaccatg ctaaagaatt gattactcaa ggtaaaatcg gtaaagttct
     6541 ttattgccat gccgctcgta caggttggga agaacaacaa ccaactgtat catggaagaa
     6601 acttcgttct caatctggag gacatttgta ccaccatatt catgaattag attgcattca
     6661 gttcatcatg ggaggacttc ctgaaaaagc gacaatggta ggaggcaatg tatatcataa
     6721 aggtgaaaac tttggtgatg aagatgatat gctcattgta aacctagaat actctgatga
     6781 tcgttatgct gttttggaat atggtaatgc tttccgttgg ggtgaacact acgtcttgat
     6841 tcaaggaact gaaggagcta tcaaacttga cttgttcaat actggaggta ctcttcgtgt
     6901 taaaggtgaa ggagaatcac acttcttagt acatgaaact caagaggaag atgatgaccg
     6961 tacagctatc tataccggtc gtggtatgga tggagcaatt gcgtacggta aaccaggagt
     7021 acgttgccca ttatggttac aaacatgtat tgataaagaa atggaatatc tacatgacat
     7081 cattaaaggt ggagaaatta cagaagaata tgaaaaactt ctcaatggtg tagctgcttt
     7141 agaatcaatc gctaccgctg atgcatgtac tttatcagtt aaagaagatc gaaaagtaag
     7201 tctttcagaa atcacaaatg cttaactatt gtaaaacaga atagtaaatt cttgtcatta
     7261 tataatttct aaagttctgt gatacaactc attgaataaa gaaatagaga tgggactggg
     7321 ataatgccca gtcccatttt ttatcaaaaa gtaatgagat caaaaatgtg ggagtgatga
     7381 aatgaagatt atagggatcg atattggcgg aacaacaatt aaggcagatt tatacgatga
     7441 ttttggaacg agtttaaatc agttcaaaga gatagaaaca attattgact atgatttggg
     7501 aacgaaccag atattaaatc aggtctgtga tttaattggt gagtatgttt taaattattc
     7561 aattgatggt gttgggattt ccactgctgg agttgttaat gctaatacag gagaaatcat
     7621 ctatgcaggc tatacaatac cagggtatat cggagtaaac tttacttccg aaatagaaaa
     7681 acgttttggg ttgtctactt ttgttgaaaa tgatgttaat tgtgctgcat taggtgaatt
     7741 gtgggaggga caagccaaag ataagaaaaa tgtagtaatg gttactattg gaacaggtat
     7801 aggaggcagt attattgtca atggacaaat tgttaacgga tttaactata ctgctggtga
     7861 agtaggctat attcctgtag gtaattcgga ttggcaaagc aaagcctcaa caaccgcatt
     7921 gattcattta tatcaaaaga agagcttgaa aactaatcaa actggacgta ctttctttac
     7981 tgatttaagt tctggagata aagtcgctaa agaaactttt gaaatttttg tagaaaatct
     8041 aacaaaaggt ttattaacta tttcttatct acttaatcca gaaattctca tattaggagg
     8101 tgggattctg gctaaaaagg atattttgtt acctgaaatt caaagttctt tagctaaaaa
     8161 tgcaatggat aataggtttt tgcctaaaaa tgttgtggca gctacattag gaaatgaagc
     8221 tggtcgtata ggagctgtaa aaaatttctt agatagaatt tctaataaat agtgtgaaag
     8281 ataaggaggt gtcacaatga ctaactctgt attttcgaca atgcaagata ttgagaatgt
     8341 tgcaaccgat attataaaat catatgataa tgagatttat acgtataaag ctgtctccca
     8401 agaagaattg gaaaaactag aaaaaagtta tgatgaaaaa agtcacgaag aattaatttc
     8461 aatagaaagc aatttagaaa tgaaacaaca gaacctcatt gatgaggtta ataaaacaat
     8521 caaggaaaat gatgcaaaga ttcagtatat ttcatcaagt aggagaggag aatttgtaga
     8581 aaaaattatt ggtagggtgg tagaaaaata tggctattag tcagatgaaa agaatttctc
     8641 tactatttac taagagtagt cttgatgatg ttttaaaaac tattcaagaa ctagagtcag
     8701 tgcagttccg tgatttaaag gttcaggata actggtcaga agcgctagaa aaagatgagg
     8761 ttgtattttc aactattcaa atttctcaca cttctaattc ccatcatggg gttattgaag
     8821 gaaatgatgc cttgaattat ttgatgaata aacaacaaca tttggaagca actgtagaga
     8881 aattacaaga atacctaccg aaagaaaaca cgtttaagtt attacagcaa cctccgataa
     8941 caacctctta tgaagaatta gaaaaatttg gtaaagctaa tgttgctgag ggtgttctta
     9001 aaaaagtgaa tcatcaaata aacagagttc atgaattaga aagaaacatt caaagtaata
     9061 atgaggaaat agagagatta ataaagtggg aaaaattaga aattattcct gcgcatttag
     9121 aacaattttc tttctgtaga ggaaaagtcg gaacaattcc aaggactgta gataatcgct
     9181 tatacaataa ttttttagaa aacaatattg aagttcaaga aatattttct aatgatagag
     9241 agtacggtgt tgttgttttc tatcagtcca gttgctctat tgattttgat gaatacttat
     9301 ttgaaccatt tgattattct agaaaggaat taccgaagca gcgagtagta gatttggatc
     9361 aagaaaacat gcagttaata actgaaaaag agaatattat cgcatcgttg caagattcaa
     9421 agaaaaattt gatagattta caatggcaaa ttgactatat tttatctatc tatgctcgtc
     9481 aaatctctaa gaataacctt ttgagcactc cgcatctagt tgcattagaa ggatggatag
     9541 aagaaactcg tattttatat tttataaaag ttatggatga gcgttttgga cattctattt
     9601 atatttatga atcggaaaca ttgtcggata atcaagatga aatacctatc aaattaacga
     9661 atcactcttt aattgaacca tttgaattat tgacagaaat gtatgctctg cccaaatatt
     9721 atgagaaaga tcctacacct gtattagcac cattttactt tacatttttt ggaatgatgg
     9781 ttgctgattt aggctatggt ttactattgt ttttaggaat aatgttagca ttaaaaattt
     9841 ttcatctacc ttcagtaact aagaaatttt taaaattctt taatatatta ggggtagccg
     9901 ttgcaatttg gggtggaatc tatggctcat tttttggata tgagttgcca tttcatctga
     9961 taactacaac ctcggatgtc atgactatat tagtagtgtc agttgtgttt ggatttatta
    10021 cagtatttgt aggtttgtta gcttcaggac tacaaaaagt aagaatgaag aaatatgcag
    10081 aagcatataa ttcaggattt gcgtggtgtg ttattctgct tggcttgtta tttattgctg
    10141 tcggaatgtt gatgcctgat attagaccgt tatttgtatt agggaaatgg gtatctattt
    10201 ttaatgctgt ggggattttg attgcttcta ttattcaagc caaaagcttg tcaggtattg
    10261 gctcaggatt gtttaatcta tataacattt catcttatat aggtgattta gttagtttca
    10321 ctcgattgat ggcattagga ttatctggag caagtatagc atcagctttc aatttaattg
    10381 ttggtttgtt tccggggaca ttggctaaac tgacaattgg attagtatta ttcattcttt
    10441 tacatgcgat caatattttt ctatcgttac tatcaggata tgttcatgga gcgcgtctga
    10501 tatttgttga attttttggt aagttttatg agggtggagg aaaaccattt caacctttga
    10561 aggcttctga gaaatatatt aaggttatta caaagaatta atggaggata tatataatgg
    10621 aacatttagc aacttatttt tcaacctatg gaggagcttt cttcgctgca ttgggaattg
    10681 tattggcggt tggattaagc ggtatggggt ctgcttatgg agttggtaag gctgggcaat
    10741 ctgccgcagc tttactgaaa gaacagccag aaaaatttgc ctcagctttg atattgcaac
    10801 tattgcccgg aacacaagga ttatatggtt ttgttattgg aattttgatt tggttgcaat
    10861 taactccaga acttcctttg gaaaaaggcg ttgcttattt ctttgtagct cttccaattg
    10921 ctattgtagg atacttttcg gctaagcatc aaggaaatgt agcagtagcg ggaatgcaaa
    10981 tcttggctaa aagaccaaaa gaattcatga agggagcaat tttggctgcc atggtagaaa
    11041 cctatgcaat tcttgccttt gtcgtatcat tcattttgac ccttcgtgta taagaaatta
    11101 atttgctatt caaaggaggt gtctaaatga gcaatttaga aaacttacga gaatctgtta
    11161 ttgaacaagc tcatgaaaaa gggagtatga aattattgga ttccaaaaag aagattgatg
    11221 atgaatttga aatgcaaaag tcggtcattg taaagaaaaa agaagctgaa catgaacgaa
    11281 agttaaaaga attacaacag aaatatcaaa taatttttca acaattaaaa aataaggaac
    11341 gccaatcaac gttagtatca aaacagaaaa tattaaaaga actttttcaa tctgctttaa
    11401 tagaaatgga atcttggagt gcagataaag aaatggagtt catctatcga attctggaac
    11461 gatattcaca acaagaggtc atagtaactt ttggggagcg gactttagct aaattcaatt
    11521 tggaacaatt agagaaattg aaattctctt ttccaaatca tttatttagt gaacagccta
    11581 tctcaaatga atcaggctta cttatttcaa taggtaaaat tgatgataac tatttgtata
    11641 aaacgttaat tggatcgatt tctaaggaag aaagttcaag tatcgcaaa
//
LOCUS       DAVLBE010000056        11592 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.056, whole genome shotgun sequence.
ACCESSION   DAVLBE010000056 DAVLBE010000000
VERSION     DAVLBE010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11592)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11592)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11592
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.056"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(118..969)
                     /gene="rgg"
                     /locus_tag="VXB91_001666"
     CDS             complement(118..969)
                     /gene="rgg"
                     /locus_tag="VXB91_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434947.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
                     /protein_id="HEV0471082.1"
                     /translation="MEQIGKVFRQLRESRNISLRQATGGQFSPSMLSRFETGQSELSV
                     EKFLFALENISASVEEILFLARGFQYDTDSELRKEITDVLEPKNVAPLEDLYRREYQK
                     HAHSHNKQKHILNAIMIKSYMKSMDERVELTAEEGKVLHDYLFSTEIWGIYELNLFSV
                     SSPFLSVSLFTRYVREMVRKSDFLMEMSGNRNLFYTILLNGFLASIECEEFTNAYYFK
                     RVIEEHFYKENETYFRIVYLWAEGLLDSKQGRVKEGQKKMEDAVRIFEMLGCNKSAEY
                     YRNTTEC"
     gene            1093..1434
                     /locus_tag="VXB91_001667"
     CDS             1093..1434
                     /locus_tag="VXB91_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEV0471083.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIKDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
     gene            1492..1572
                     /locus_tag="VXB91_001668"
                     /pseudo
     CDS             1492..1572
                     /locus_tag="VXB91_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(1688..3391)
                     /gene="ilvD"
                     /locus_tag="VXB91_001669"
     CDS             complement(1688..3391)
                     /gene="ilvD"
                     /locus_tag="VXB91_001669"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HEV0471084.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETSIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIVDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(3624..4556)
                     /locus_tag="VXB91_001670"
     CDS             complement(3624..4556)
                     /locus_tag="VXB91_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HEV0471085.1"
                     /translation="MMRSTKELRHVYRDFLLEANQSDSDIVVLEADLSSSMATHNLEK
                     DFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFASRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPVPVYQGGEDFSKGYIELRHGEDLVIVASGIMVAPSIRVADELSKLGYSV
                     SVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSALCELFSDDGITKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            complement(4553..5410)
                     /locus_tag="VXB91_001671"
     CDS             complement(4553..5410)
                     /locus_tag="VXB91_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEV0471086.1"
                     /translation="MILSKNREDGLRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDDNKKQLDGFTKDICNPGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEERQMLTSVVER
                     LSQELEETE"
     gene            complement(5414..6760)
                     /locus_tag="VXB91_001672"
     CDS             complement(5414..6760)
                     /locus_tag="VXB91_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEV0471087.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATALIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFIGGLVSMAIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFIKKPSAKEE"
     gene            complement(6773..7057)
                     /locus_tag="VXB91_001673"
     CDS             complement(6773..7057)
                     /locus_tag="VXB91_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0471088.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKLCEEKGLI"
     gene            complement(7061..9091)
                     /locus_tag="VXB91_001674"
     CDS             complement(7061..9091)
                     /locus_tag="VXB91_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEV0471089.1"
                     /translation="MFDYRALVILMTLMDHCELSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NNHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLINQVVKDYYEKLQLVPIVNQLKVCLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEYYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKWYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKASSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYDDIKMIIKQED"
     gene            9282..10289
                     /locus_tag="VXB91_001675"
     CDS             9282..10289
                     /locus_tag="VXB91_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEV0471090.1"
                     /translation="MTEKLINSKPNGVFALILIELTIVLGVFIFIMGVGSENIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNDNDVNLEIGKKQISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIIDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            10292..10492
                     /locus_tag="VXB91_001676"
     CDS             10292..10492
                     /locus_tag="VXB91_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEV0471091.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
     gene            10644..10826
                     /gene="rpmF"
                     /locus_tag="VXB91_001677"
     CDS             10644..10826
                     /gene="rpmF"
                     /locus_tag="VXB91_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HEV0471092.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKIAKAASAE"
     gene            10842..10991
                     /gene="rpmG"
                     /locus_tag="VXB91_001678"
     CDS             10842..10991
                     /gene="rpmG"
                     /locus_tag="VXB91_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEV0471093.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(11483..>11592)
                     /locus_tag="VXB91_001679"
     CDS             complement(11483..>11592)
                     /locus_tag="VXB91_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV0471094.1"
                     /translation="TVSGKWYYTYNSGDLLVNTTTPDGYRVNANGEWVG"
BASE COUNT         3751 a         2439 c         1908 g         3494 t
ORIGIN      
        1 gattcttttg aatatatgca acaaacaaaa tgagcaaaaa aacgatagaa cttttgtaat
       61 gacctgagag agggcaacag ttctatcgct tcaaattttt tcttggtttg cagatactca
      121 acattcggtc gtatttctat agtattcggc agatttatta cagccaagca tctcaaaaat
      181 acggacagca tcctccatct ttttctgacc ttccttgact ctaccttgct tgctatcaag
      241 gagaccttct gcccacagat aaacaattcg gaaataggtc tcattttcct tgtagaaatg
      301 ctcttcgata acacgtttaa aataataggc attggtaaat tcttcacact caatactagc
      361 taaaaagcca ttcaatagta tagtataaaa aaggtttcga ttgccagaca tttccattag
      421 aaaatcggat ttacgtacca tttctcgtac atatctagta aaaagagaaa cagataaaaa
      481 tggagaactg actgaaaata aattgagttc atagattccc cagatctcgg tagaaaacaa
      541 ataatcatga aggacttttc cttcctctgc tgttaactct accctttcat ccatgctctt
      601 catataagac ttgatcataa tggcatttag aatatgtttc tgtttgttgt gagaatgggc
      661 atgcttttga tactccctgc gatataagtc ctcaagaggt gctacattct ttggttccaa
      721 gacatctgta atttcttttc tcaactcaga atctgtatca tactggaaac ctctcgccag
      781 aaagaggatc tcctccacac tggcagatat attttccaga gcaaatagaa acttttccac
      841 cgaaagctca ctctgacctg tttcaaaacg ggacaacata gacggcgaaa attgtcctcc
      901 ggttgcttgt ctcagtgaga tatttcttga ctctcgtaat tgtctaaaga cttttccaat
      961 ctgctccata gacttcccct tgattccgta ttttcttcat tttatcatat ttttcagaaa
     1021 attcatcaaa aacttgccaa attgtcagaa ttatgagaaa atagaggata tttatcacgt
     1081 ggagggactg ctatgagaga cgatatcaaa atcaatgacc gtgctttggc cttgcaagac
     1141 caaatcatcg aaaaactaga gaaagttttt gatacagatg tggaattgga tgtttacaat
     1201 ctaggtctga tttatgaaat caatctggat gaaacggggc tctgcaagat tgtcatgacc
     1261 ttcaccgata ctgcctgtga ttgcgccgaa agcctgccta ttgaaatcgt ggcaggtctg
     1321 aaacaaatcg agggtatcaa agatatcaag gttgaagtta cctggtcgcc tgcttggaaa
     1381 atcacacgaa tcagtcgcta tggccgtatt gcccttggac taccacctcg ttaagcaggc
     1441 caatcatttt taaagatgaa aaaagcaagc caaaaatggc ttgctttttg atactcaatg
     1501 aaaatcaaag ggcaaactag aaaactagcc gcaggttgct caaaacactg ttttgaagtt
     1561 atggatagaa ctgacgaagt cagcccaaaa cactgttttg aggttgtgga tagaactgac
     1621 gaagtcagta accataccta cggcaaggcg acgttgacgt gatttgaaga gattttcaag
     1681 tatgagttta ttttttacct gacttgtcca tattccagaa gtctgtcacg gctccgcgtg
     1741 aagcagatga tacgatatgg gcatatttac cgaggacacc acggctgtaa agtggtggca
     1801 aggttgtttc tgccttgcgt ttttcaagtt cttcttcgga tacggccatg gaaatttctt
     1861 tggtatcttg gtcaaccgta acgatatcgc cggtacggag ataggcaatt ggtccaccat
     1921 cctgagcttc aggagcgata tgtccaacaa ccagaccata agtaccacca gagaaacgtc
     1981 cgtccgtcaa gagggccacc ttatctccct gacctttacc aacaatcatt gaagaaagtg
     2041 acagcatctc aggcatacca ggaccacctt taggtccaac aaaacgaaca acgactacat
     2101 cgccatcaac gatttcatct gtcagaacgg cctgaatcgc atcttcttct gagtcaaaga
     2161 ccttagctgg cccaacgtga cgacgcactt taacacctga taccttggca actgcaccgt
     2221 caggagcaag gttcccgttc aagatgataa gcggaccatc cgcacgtttt ggattttcaa
     2281 gtggcatgat aactttttgg cctggagtca agtctgcaaa gtcagccaag ttttcagcta
     2341 cagtcttacc agtacatgtg atgcgatctc cgtgaaggaa accatttgcc aacaagtact
     2401 tcataaccgc agggacacca ccgacttcgt agaggtcttg gaagacatac tgaccagatg
     2461 gtttcaagtc ggccaagtga ggcacacgtt cttgaatcgt attgaagtcc tcaagtgaca
     2521 agtcaacatt tgcggcatgg gcaatggcga gcaagtgaag agtggcgttt gtagaaccac
     2581 cgagagccat cgttacagta atagcatctt caaaggcttc acgagtcaag atatctgatg
     2641 gtttgagacc aagttccaac atcttaacaa cagcacgtcc tgctgcttcg atatcttctt
     2701 tcttatcagc tgattcagct gggtgagagg atgaccctgg caaactcatc cctagaactt
     2761 cgatagcagt tgccatggta ttagcagtat acataccacc acaaccacca gggccagggc
     2821 aggcattaca ttcaagacgt ttcacgtcct cagctgtcat gtcaccgtgg ttccattttc
     2881 cgataccttc aaagacagaa accaagtcga tatctttacc atcaagattt cccggtgcaa
     2941 tagttccacc ataggcgaaa atagctggga tatccatatt agcaatagca atcatagatc
     3001 caggcatgtt cttgtcacag ccaccgatag cgacgaaggc atccacgttg tgaccactca
     3061 tagccgcctc gatggagtcc gcgatgatgt cacgagatgt tagagagaaa cgcataccag
     3121 gcgttcccat agcgatcccg tccgctacgg taatggttcc aaactgtaca ggccaagcgc
     3181 ctgcagattt gacaccttct ttagccagtt tcccgaaatc atgcaagtga atgttacatg
     3241 gtgtattttc cgcccaagtc gaaatcactc ccacaatcga tgtttcaaag tccttatctg
     3301 tcataccagt cgcacgaagc atagcacggt taggtgattt aaccatgctg tcatagatgc
     3361 tactgcggtg acgtttatct aattcagtca tcttatccct cccatttcag tttttactat
     3421 tatagcacaa tttaaaggca atgaacagaa taaaattctt gaattttcag aaaattctat
     3481 acgcatgtga aatatttaaa attaaaaaca acaaagcgga ttagtgcact ttctgatgac
     3541 cagaatatgc tttttaatcc gctttcttta aataacgtac tgtaattttt acagaaattc
     3601 tttcagataa gtgtatttaa catctatctt gcattataaa tttctagaac cttctctttt
     3661 atattcgatt cactcaaacc atactcatta agaagataat ccattttccc tacttgaccg
     3721 aatctttctt gaacacccat ccgatgaatt tttgttattc catcatcaga gaataattca
     3781 cataaagcac tgccaattcc acctatctga ttgtggtttt ctacagtaaa tatagttttt
     3841 ccacttaaca ttgtttttat ctgttctggt atcggtttga ttctaaataa atctatcaca
     3901 cttactgaat aacctaattt agacagttca tctgcaactc gaatacttgg agcaaccatt
     3961 ataccagaag caacgattac aagatcttca ccatgcctta actcaatgta gcctttagaa
     4021 aaatcttctc caccttgata cacaggaact ggagcttttc taattgttcg aatatatttt
     4081 agtcctttta agtctaatgt ctggttcaat atttcacgaa attggatatc atcagttgct
     4141 tcaaaaatga tcgatttagg aattaaacgt aacaatccaa tttcttcaaa tggcatatgt
     4201 gtcccaccat tcatttctgc agttactcct gcatctgatc caatcacagt ggcatccaat
     4261 tgtgcgtatc caagagaaat aaataattga tcaaatactc ttcgtgaagc aaaaggacca
     4321 aatgtatgaa gataaggtct aaacccctga atagacaagc ctgctgcaag gccgaccatt
     4381 tctgcttcca taatcccaac attcacataa cggtctccaa agtccttttc aagattatga
     4441 gtagccatcg aacttgacaa atcggcttct aagactacta tatcagaatc actttgatta
     4501 gcctctaaaa ggaagtctct atatacatgc cgtaattctt tcgtgcttct catcattctg
     4561 tttcctccaa ttcctgactt aatctttcta caactgaggt taacatttgt ctctcctcta
     4621 cagtagggcg aagatgatga ttggatttca tttcttccag ctcttgaacc ccttgacctt
     4681 taatagtatc taatacaatg cacttaggtg atgaattatt tgactgtttt aattggacaa
     4741 tcccttcata aatttctcta atatctgaac ccttgaccct aatggattca aatccaaatg
     4801 ctgaaaattt ttctacgaaa tcacctggat tacaaatatc ctttgtaaaa ccatctaatt
     4861 gttttttgtt atcatcaaca aatacaatta agttggataa ctgttgatga gaagcaaact
     4921 gtatagcctc ccaacattgt ccctcattta actcaccatc tccaacaata gcataagtat
     4981 aaaagggact ctttcttatt ctctgaccat atgcaagtcc agttgcaaca ctaattcctt
     5041 gtcctaaaga gcccgttgtc atatctatgc ctggcgttag atttctatca ggatgagacg
     5101 gtaatttggt tccatttgta tttaaagaat ataagaattc tttgtcaaag aaaccattca
     5161 aatagagtgt actgtataga gctggtcctc catgaccttt tgataatatg aaataatctc
     5221 tatctcgtgc tgcaaatatt tctggagtca ttggcattat ttcaccataa agcactgcta
     5281 aaacttctac gatagacaga cttcctccgt aatgtccgaa tccaagatga ttcaatgttc
     5341 taagagtatt taatcggatg ttagtcgcaa attttcttaa cccatcttct ctatttttac
     5401 ttaaaatcat cccttattcc tcctttgcag atggcttttt aataaaggat actccaaaca
     5461 taactgctag aataagaaca agaccaatca caatgcctgc ttgtgagcca aattgattta
     5521 acattcctaa aataattcct gatagaccaa aatctgcatc tgagaaagtt gatccttgga
     5581 aaccaagtcc tcccaaaact ggcattaaaa agactggaag aaaactgatt aaaatacctt
     5641 gtaaaaatgc tccaatagtg gctccacgaa caccaccaga tgcattccca atgacacctg
     5701 cagtcgctcc acagaagaaa tgaggcacaa cacctggtaa gataacaacc gttcctgaag
     5761 caatcataat tgccatactt actaaaccac caataaaact agagataaat ccaattagaa
     5821 ctgcattggg tgcataagta taaacaatcg gacaatccaa agcaggtttt gaattaggta
     5881 caagacgctc tgaaatacct ttaaaggctg gaacaatttc gcccaaaata aggcgaacac
     5941 ctgctaaaat aacaaatacc cctgctgcaa attgacctgc taattgtaaa gcataaacta
     6001 gaccacttgt accactactg atttcttttt ctatatattc tgaccctgca aagatagcta
     6061 caataatgta aataactgcc atggataaag taatactaac agtactatca cgtaaaaaag
     6121 ctaaactctt tggaaattta atgtcctctg ttgattttga tttgtcaccg ataaggctac
     6181 cagtaaaacc actcaaccaa tatcccaaag aactgaaatg acctaaagcc accttgtcat
     6241 ttccagttaa ttgaaccata tatttttgaa caaatgctgg ggaaatactc ataataatac
     6301 cgagtgctaa tcctcctagt aagataagag gcaagctagt aaagccagca actgataaaa
     6361 tgaccgcaat catacatgcc atatatagag tgtggtgccc tgttaaaaaa atatatttaa
     6421 atcgagtaaa acgagcgatt aagatattga acaccatgcc tgcaaacata atcagtgcag
     6481 tagctgagcc atatgttgtt aaagctacag ctacaattgc ttcattattc ggcacaacgc
     6541 cagataaatg aaaagcatgc tcaaacatgg taccaaatgg atttaaagaa ttttgtacaa
     6601 ttcctgcacc accagataca actaagaaac caacaaaggt cttaattcca cctttaataa
     6661 tatcaggtaa tttcttcttc tgaagaacta atcctaaaat tgcaattaaa gctactaaaa
     6721 tagctggtgt actaacaata tccaatatga acttcatcat gacgctagcc tcctatataa
     6781 gtcctttttc ttcacaaagt ttagtaatta attctcgtag ttcatccata tcaataatac
     6841 tatttaagat acgaacatct ccaagatgac tagctgaatc agctagatca cgaccaacaa
     6901 tccaaatatc agctgcattt ggatctgctc cacctaaatc ataatgttca acttctacat
     6961 ctgaaacatt caaatcactc aatacagatt caatattcat ctgtaccata aaacttgaac
     7021 ctaatcctga accacaagct gtaccaattt ttaacattat ctaatcctcc tgtttaatta
     7081 tcattttaat gtcatcatag ttttttgatg atattaaagt ttgaacatga tttttatctc
     7141 ttaaaattgt tgttaaatgt gacaaagcct ttaaatgact ctcattatca atggctgcaa
     7201 tacaaatcaa caatcttacc tcttgttctg gattatccaa taaataaatc ggttcttcca
     7261 aaactaacat tgacattcct atttcattca caccttcatc tggccgagcg tgaggaattg
     7321 ctactccctt ccctaaatta ataaaaggcc caaactcttc tactttttga atcattgcct
     7381 cagggtagtt ctcagttatc ttatcttgat ccaaaagcgg tttagctgct aaacgaatcg
     7441 cctccttcca tcctaatttt tgcgaactaa cctgataggt ttctttggta atgagttgtt
     7501 ctagcactgg tacaatttcc tttctatcat ttttttggta aagataattc tttaacgcca
     7561 atcttaattc caattcttgt gtaataattc catatctttt gacaatattc agaatttgtt
     7621 caatctcaaa atccccatac tctaaattcg gaaaatcttt taacactagt tctactagtt
     7681 gtattgcttg ctcttcagtc atcataaccg aaactagata atttggcttt tctgtctcca
     7741 cctttatggt agaaaaaacc atatcatagt cactactagc tttcacctgt aaatcatcaa
     7801 tctttgaggt tcctataaac tcaatttgag gaaataatgc taatagattc tcttttaaca
     7861 tcaatgaaga actaacacca ttaggacaaa tgattgctgc tttataccat ttttgaggca
     7921 aagtatctgc tttctttaaa taacctccga aatggataac aaaatatgct gtttcactat
     7981 caggtatggg attgtcaata gcgtccatca agggcatcaa agaatctttg actaattcaa
     8041 ataaatcagg ataatattct ttaacatgca atacatattc atttgaacta ggtaggccga
     8101 actttaatct atagtaagcc ggtataaggt ggcggcgaag attttctctc aatccttccc
     8161 tttgtttaaa atgtaacaaa gaaatatctt ccattctact tataatagcc tctgttaatt
     8221 gattaaagta aaccggagca acatctactt caccttcaaa gcaacttgat aataaaactg
     8281 tgatatagcg ataatcatcc tcagaaaaca ccgtatctat aattcccaaa tcaaccactg
     8341 tatccaataa aatagtggtt atatcttgaa taacaggaga tactaatgtc tctgaaagac
     8401 atactctttc aacatccctt tgatacctac acagaatgaa tactaaaccg aaaaggcaaa
     8461 cttttaattg attaacaata ggtactagtt gtagcttctc ataataatct ttaactacct
     8521 gatttatcaa atcataagtt aatgaatacc cccaactgga taaaacataa tccaaacccc
     8581 aaatccctat ggaggattcc agcaactcac taaccatttg aaaagctaag cggtgcttat
     8641 tccactctga accgtgtaaa gtataacctt ttgctctact gtaccctagc tccaaatcat
     8701 tatctaacat aatctttctt aatgattgaa tatcagataa ggttgtattc ttacttactt
     8761 tcaaaaagtc ttggtaatga ttattcgata taaaatctaa tcggcaaaaa gtgtaaagat
     8821 agattaaagc taagcgagtc gactttggta aaaccaattc atccgactta ataatatctg
     8881 tcaaagactg cttcgtacga tttgataaac tatagcgacc ttgtttttta tccagcacta
     8941 tccctttatt agctagataa ggcactaaat aatctattcc ttctttgact tcctttatag
     9001 gtaagctcac cttaacagat aattcatata atgatagctc acaatgatcc atcaaagtca
     9061 tcaaaataac tagtgctcta taatcaaaca tttctcttcc tttctaacta caattatagt
     9121 gtaaaaatta taagaataaa agagtatttg agcacaatat aatctcacct tttaaaagaa
     9181 attattgggc tgaaagtttt tagtgattat tttcaacttt ctattgactt ttaaaaacaa
     9241 agtgatatca tttagatatc aaataatggg aggtcattct tatgactgaa aaactaatca
     9301 attcaaaacc aaatggtgta ttcgcattga ttctcattga gttgacaatc gtacttggtg
     9361 tctttatatt tataatgggt gttggttcgg aaaacatttt tggaattatt atcggacctt
     9421 tactaatcgt aattgcaggt ctagctcatg ctggtttaaa agttgtcaaa cctcaggaag
     9481 ctctggttct gacactcttt ggtaactata caggtaccat caaagaacct ggtttttact
     9541 ttgtcaatcc cttcagcgta gcagtcaacc ctgcaaacca cactcgactt ggacaaagtg
     9601 gtgatgttag cacaaaatct ccttttttag gagctaaatc atcaaatgac aatgatgtaa
     9661 atcttgaaat tggcaagaaa cagatttccc tcaaagtcat gaccttgagc aattctcgtc
     9721 aaaaaatcaa tgattgctta ggaaaccctg tagaaatcgg tatcgcggta acttggagag
     9781 ttgtcgatac cgctaaggca gtcttcaacg ttgataacta caaagaatat ctttcattgc
     9841 aatgtgatag cgccctccgt aatattgtcc gcatctatcc ttacgatgtg tctcctaatg
     9901 tggatactac gggtgacggg caagcagatg aaggtagtct ccgtggctct agcgaaattg
     9961 ttgctaaccg tattcgtgaa gaaatccaaa gtcgtgttga ggatgctggc ttggaaatcc
    10021 ttgaagcacg tatcacttac ctagcttatg ctccagaaat tgctgccgtt atgcttcaac
    10081 gccaacaagc atctgccatt attgatgcac ggaagatgat tgtagatggt gctgtaggaa
    10141 tggttgaaat ggcactagaa cggctcaatg aaggggaatt ggtagaactt gacgaagaac
    10201 gaaaagctgc catggtttca aatctccttg tcgttctttg tggcaatcat gatgcacaac
    10261 caattgtcaa cacaggaagt ctttactaaa gatggctgaa gctaaaaaaa agcagatccc
    10321 ccttcgactc tcaacaaagt tatacgctgc actcgcatca tgggcagaag acgactttcg
    10381 ttcagtcaat gggcaaatcg aatatctcct cacagagtgt gtcaagcaac ggaagaaaga
    10441 cggaaaatac gtatcagaaa ccattgacga accatttgag attgatattt aacatcttct
    10501 cctgtctgac aagtcggaca ggagaatttt ttcatctttt tttgtcaagt aactttactt
    10561 tacaaaaaaa atgtgttatc ctagtatggt tgatgaaaat cagtagattg aatcgaatat
    10621 aaatacctaa aggagaaatc aaaatggcag tacctgcacg tcgcacttca aaagcgaaga
    10681 aaaacaaacg tcgtacacac tacaaagtaa cagctccatc tgtaaacttt gacgaaacta
    10741 ctggagatta ctcacgttct caccgtgtat cacttaaagg atactacaaa ggacgtaaaa
    10801 tcgctaaagc tgcatcagct gaataataga agggagatac catgcgcgta aatattacac
    10861 ttgaacacaa agaatctggt gaacgcttgt accttacttc taaaaacaaa cgtaacactc
    10921 cagaccgcct tcaattgaag aaatactcac caaaacttcg caaacacgtt gtgtttacag
    10981 aagttaagta agcattcaat acgaatcaat acagaagaaa aacgcttgat cagcgttttt
    11041 tctttttgtt aatttcacta tattgcaagg gaaatcattc gaatgactac atttttcact
    11101 accttttttg aaataagaat acggattcgg acgattaaaa gtaagagaaa ctcaaatgta
    11161 agttggggtt ccttttttgt atatttttca aataacgcct ctacactatt tgtagcaaat
    11221 tcaccaacta cagttgtatc ttagttaaaa taagttagaa tatgtaagtg agtaccagat
    11281 ataccaagac atcgtcacca tctaaggtat attcaaaata caaaagttga ccaactagat
    11341 ttctgaatat ccttatatat ccattcttaa aattggttta aatagcgtag tcttttaaac
    11401 tagttttgag aatccaaaaa atcttcctac atatgtaaga agatttttta gttcagaatg
    11461 attagattta gctaatggat acctatccta cccactcacc gttagcattg actcgatagc
    11521 catcgggtgt agtcgtgttt actaataaat ctcctgaatt ataggtatag taccatttac
    11581 cagaaactgt aa
//
LOCUS       DAVLBE010000057        11526 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.057, whole genome shotgun sequence.
ACCESSION   DAVLBE010000057 DAVLBE010000000
VERSION     DAVLBE010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11526)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11526)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11526
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.057"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            231..1184
                     /locus_tag="VXB91_001680"
     CDS             231..1184
                     /locus_tag="VXB91_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element ISSpn8 family transposase"
                     /protein_id="HEV0471095.1"
                     /translation="MQEHYTPKGKHLTIDNRRLIERWKNENKSNREIAGLLGKAPQTI
                     HTEVKRGTTLQQVRKGLYKKVYSADYAQTVYQFNRKRSVKKLILTKEIREKILHYHKQ
                     KFSPEMMVNKKQVKVGISTIYYWFHNGHLGLTKADMLYPRKRKGVKKQASPNFKPAGK
                     SIEERPDVINLRLENGHYEIDTVLLTKIKNYCLLVLTDRRSRHQIIRLIPNKTAESVN
                     QALTLLLGEHHILSITADNGSEFKRLSEVFPEEHIYYAHAYSSWERGSNENHNRLIRR
                     WLPKGTKKTTPKEVAFIENWINNYPKKCLDYKSPSEFLLGG"
     gene            complement(1213..2427)
                     /locus_tag="VXB91_001681"
     CDS             complement(1213..2427)
                     /locus_tag="VXB91_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV0471096.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            complement(2583..2877)
                     /locus_tag="VXB91_001682"
                     /pseudo
     CDS             complement(2583..2877)
                     /locus_tag="VXB91_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            3039..3491
                     /locus_tag="VXB91_001683"
     CDS             3039..3491
                     /locus_tag="VXB91_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEV0471097.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIAHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            complement(3526..4914)
                     /locus_tag="VXB91_001684"
     CDS             complement(3526..4914)
                     /locus_tag="VXB91_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV0471098.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     SASPSEEDFGQAVSQLHQALDKAAGKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQL
                     KAYERHKERNKS"
     gene            4980..5942
                     /locus_tag="VXB91_001685"
     CDS             4980..5942
                     /locus_tag="VXB91_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HEV0471099.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HALDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGLIMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKDYMEG"
     gene            complement(6148..7158)
                     /gene="ccpA"
                     /locus_tag="VXB91_001686"
     CDS             complement(6148..7158)
                     /gene="ccpA"
                     /locus_tag="VXB91_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HEV0471100.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLVKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
     gene            complement(7582..8181)
                     /locus_tag="VXB91_001687"
     CDS             complement(7582..8181)
                     /locus_tag="VXB91_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0471101.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLAFQADVESVLQAKNGQEAIQLLEK
                     ESVDIAILDVEMPVKTGLEVLEWIRAEKLETKVVVVTTFKRPGYFERAVKAGVDAYVL
                     KERSIADLMQTLHTVLEGRKEYSPELMEVVMTRPNPLTEQEIAVLKGIARGLSNQEIA
                     DQLYLSNGTIRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(8182..9279)
                     /locus_tag="VXB91_001688"
     CDS             complement(8182..9279)
                     /locus_tag="VXB91_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV0471102.1"
                     /translation="MLERLKSIDYMYWASLIFMIFPILPVVTGEIPSWHLLIDILFVV
                     AYLGVLTTKSQRLSWLYWGLMLTYVVGNTAFVAVNYIWFFFFLSNLLSYHFSVGGLKS
                     LHVWTFLLAQVLVVGQLLIFQRIEVEFLFYLLVILAFVDLMTFGLVRIRIVEDLKEAQ
                     VKQNAQINLLLAENERSRIGQDLHDSLGHTFAMLSVKTDLALQLFQMEAYPQVEKELK
                     EIHQISKDSMNEVRTIVENLKSRTLTSELETVKKMLEIAGIEVETDNQLDTASLTQEL
                     ESTASMILLELVTNIIKHAKASKAYLKLERAEKELILTVSDDGCGFAFLKGDELHTVR
                     DRVSPFSGEVSVISQKHPTEVQVRLPYKERK"
     gene            complement(9279..10016)
                     /locus_tag="VXB91_001689"
     CDS             complement(9279..10016)
                     /locus_tag="VXB91_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0471103.1"
                     /translation="MKRWIALSKIEFLLTKRQLIYYLLSVGMPTAFYLFFSGIYQDTP
                     GELANFMRDYLISMTAFSMMSTAMFSFPAVLHTDKINNWQKTLRHTPVNMVEYYLSKI
                     TSMMVDYLVSILVVFSVGHFVRGVDMPLGSWIGAAFLLIVGSVAFVALGLTLTLLPSS
                     QLMSVVGNLLYLGLAVLGGLWMPISLFPDWMQAIGKCLPTYQLMELLKTFLNEGGINL
                     SATVYILVFSAVLFGLTIYLQGHKENA"
     gene            complement(10018..10902)
                     /locus_tag="VXB91_001690"
     CDS             complement(10018..10902)
                     /locus_tag="VXB91_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0471104.1"
                     /translation="MNMIKVESLNKNIKGKAILKGISFEVAEGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVSIQGLSVTSSQLDYIRGYLPQENVIVQKLKVKELIAFFQRIY
                     PNSLSDQEIDQLLQFDQQQKEQFAEKLSGGQKRLFSFVLTLIGRPKLVFLDEPTAAMD
                     TSTRQRFWEIVRDLKAQGVTILYSSHYIEEVEHTADRILVLNKGELIRDTTPLAMRSE
                     GIEKHFILPLAYKEVIEQSNLVENWSQKQDALQVVTREADAFWELLAQAGCRMQEIEV
                     NNRSLLNTIFEETQKGDN"
     gene            complement(10889..11083)
                     /locus_tag="VXB91_001691"
     CDS             complement(10889..11083)
                     /locus_tag="VXB91_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0471105.1"
                     /translation="MKRGIIYFFIGLSLLVWLVEMFTGWFDQTLLRQFIRGALGFGFM
                     IFVVFLMRMEWLKGEYHEYD"
     gene            complement(11080..11211)
                     /locus_tag="VXB91_001692"
     CDS             complement(11080..11211)
                     /locus_tag="VXB91_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000490981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine aminotransferase"
                     /protein_id="HEV0471106.1"
                     /translation="MFSGLDESFYHFPWELFAGFGMMSWLVREGLKLVGDVKKEFEE"
BASE COUNT         3544 a         2595 c         2131 g         3256 t
ORIGIN      
        1 taccttagtc aagaattaga tgtttcacta tgtttgagta agttgatgat ttcatttgat
       61 aacaggtttg aaactgttag gctaggtggc caaggctaat catagccttg gtttagctga
      121 aaaaacaggt tcaagggttc ctgttgtcaa atgaaatgtg atttaaggta taagaaaaca
      181 cctctgtgct atacttgttg ttcaccacaa acacaaggaa aggcacagag atgcaagaac
      241 attatacccc aaaagggaaa catttgacaa tagataaccg tcgcttgatt gagcggtgga
      301 agaatgaaaa taagtccaat cgtgaaattg caggcttgtt aggaaaggcg cctcaaacga
      361 ttcatactga agtcaaaaga ggtacaactt tacaacaagt gagaaaaggg ctatacaaaa
      421 aggtctattc tgccgattac gcacaaactg tttaccaatt caatcgaaaa cggtcggtga
      481 aaaagttaat tttaacaaag gaaatcagag agaagatctt acactatcat aagcaaaaat
      541 tttcgcctga aatgatggtt aacaagaagc aagtgaaagt tggtatttca accatctact
      601 actggtttca taatggtcat ttaggattga cgaaggccga catgctttat cccagaaaaa
      661 ggaaaggtgt caagaagcaa gctagtccga actttaagcc ggcaggtaaa tctatcgaag
      721 aacgtcctga cgttattaat cttcgcttgg aaaatggtca ttatgaaatt gataccgtcc
      781 tactgactaa gataaaaaat tattgcctgt tagtcttaac cgaccggcgg agcagacacc
      841 aaattataag gttaattcca aataaaactg ctgaatctgt caatcaggcg cttacgttac
      901 tattagggga gcatcatatt ctgtccatta ctgcagataa tggttcggag ttcaaacgat
      961 tgtctgaggt atttcctgag gaacatatct actacgcaca tgcttactct tcatgggaga
     1021 gaggttcaaa tgaaaatcat aatcgattaa ttcggagatg gttacctaaa ggaaccaaga
     1081 aaacgactcc gaaagaagta gcttttatcg aaaattggat taacaactac cctaaaaaat
     1141 gcttggacta caagtcgcca agtgaatttc ttttgggtgg ctaacttcaa cttgaaattt
     1201 gggatgcaag ccctatctac gatactgttt caagaaacga gtcatctttt cttggatttg
     1261 ggctaactca tcaacacgag gaaggtaaac gatacggaag tggtctggtt cctgccagtt
     1321 aaagcctcga ccatgaacca agagaacctt ttcctgcttc aagaaatcaa ggacaaactg
     1381 ctcatcatca tcgatacggt acatattgcg gtcgattttt gggaagatat agagccccgc
     1441 cttgggttta acggcagaca aacctggaat atcttgaatg gcattataga tgaaatttct
     1501 ttgctcgtag attcgtccac caggaagaag caattcatcg actgattggt gaccccccaa
     1561 ggaagtttgt acgacttgtt gggccaaaac gttagagcaa aggcgcatat tggacagcat
     1621 attgagccct tcgatatagc ccttaacatg agtcttaggg ccagacaaga ccatccaacc
     1681 cacacggaaa cctgctatgc ggtgggattt tgacagacca ttcatgctga cacagaagac
     1741 atctggtgcc aagctcgcca caggcgtatg cacatgtccg tccattacca tgcggtcata
     1801 gatttcatcc gcaaagataa tcaaatcgtt ttgacgggca atctcaataa tctccagcaa
     1861 gagttcctta ggataaaggg ctccagttgg gttatttgga ttgataagga caattgcctt
     1921 ggtattggaa gtgatttttg acttgatatc gtcaatatct gggtaccatt ccacagcttc
     1981 atcacagata tagtgaacgg catttcctcc agctaggctg acagccgccg tccatagagg
     2041 atagtctggc attggcacta agacctcatc cccattgtcc aaaagcccct gcatggacat
     2101 gacaatcaac tcactgacac catttccaag gtaaatatca tcaatatcta cgtttgggaa
     2161 tttcttcagc tggcaatact gcatgatggc cttacgggct gagaaaatcc ctttggagtc
     2221 agaatagcct tcactatcac gcgcattcat aatcaagtca tgaatgacct cgtctggcgc
     2281 tgtaaagcca aattctgctg gatttcctgt attcagacgt aaaatctttt ctccattcgc
     2341 tcgcatccgc atggcttctt ccaatacagg accacggata tcataagcaa catgctctaa
     2401 cttactagac ttgttatatt ctttcatctt gtttcctcaa ttcatcagga tagtaacatt
     2461 ataccactag aaagagaatg cgacaagttt actgaaatgt gttactagtt tcgtatagaa
     2521 gaaaaacctt gctaaaggcg aggttaagaa cgtagagata gcaggtattt tgcaaagaca
     2581 catcacatac caaaagataa acctagaaaa aagcaagcct agaaaggagt cataaagaag
     2641 attaaacatg aggaaaagcc cccatatcat caagtaatcc caacgcccac ttcgttttgc
     2701 aactagaaat aagattagat ggtagagtac atgaaaaact aaaaatccaa taaaacttgg
     2761 ataaagaagc ggtaccagac tctctaattg acagatcatg atcacttcta ccaagactga
     2821 aactaggata attccataat aaaggaaatt tgatttttga aaagagtttt tcatcattct
     2881 cccttccttc acttctttcc tgctatcctt tcttttattt tatcatatat ttatatagag
     2941 tttaagccct aatattcttt tgaaaaatac tttttttgct ttacttctat agtgaaaagg
     3001 tttacaatta tagtaagaaa atttcaggag gtttcattat ggcacaacgt taccaaaata
     3061 tcatggtcgc aatcgatggt tctaaggaag cggacttggc ttttgtcaag ggagttcatt
     3121 ctgctctacg aaacgacgct aaactcacca tcgcacatgt cattgacaca cgcgctctcc
     3181 aaagcgtatc cacctttgat gctgaagttt acgaagaact ccaagtcgac gctgaaagtc
     3241 tgatgaaaga gtacgaaaaa cgtgctaaag atgctggggt agcagatgtt catatcgtca
     3301 ttgaaatggg aaatccaaag accctgctag cacgtactat tccagatgcc gaggaagtgg
     3361 acctcatcct cgttggcgca actggtctca acgcctttga acgcctcttg gtcggctctt
     3421 catctgaata catactccgc catgctaagg tcgatttgct ggttgtgaga gaacaagaaa
     3481 aaaccttata atcacaaaga aaaggagccc ctagctcctt tttgtttacg atttatttct
     3541 ctctttatgg cgttcgtaag ccttgagctg gcgctgcagt tcctttttaa tagcaggttc
     3601 tggagcatat ttttcttccc aattatctgg ttttaagatt ttatgggtca ctggatcaaa
     3661 atgagccttg ccatctggaa aaattttccc catattggcc tgatggacaa tatcaaaaat
     3721 acgttctggg tccaccccca tcaagacaaa actgccgtag gtgaagtaaa gcgtgtcaat
     3781 caaggcatcc acttgcccta tcaaatcttg ctgagcaggt gtcttcttgg ctactttacc
     3841 tgctgcctta tcaagggcct gatgaagttg cgatacagct tgaccaaaat cttcttcaga
     3901 aggactggct gatcgaacaa actccaccaa ttcttctatt ttaaaaccag ccctatgggt
     3961 tgcaccctct aaatcccaag ctcgaggttc ttcttgggtt cgttcatcca tcatgtggtg
     4021 gaaggtcttg accttattga aatgatagtc acggctgaca aaaacttttt ctgaagacaa
     4081 aacaccaaaa tgttccaagg ccttgtggat cccatcttgt tgattgctag tggtaatgtg
     4141 cttggcagct tccttgacac tgctactacc atttcccata gcgaccgaca taccgacgcc
     4201 agccagcatt tcaaggtcat tatctgagtc accaaaagcc atgacttggt tgaggtcaaa
     4261 gccatattct ttcccaactc ggcgaatgcc ttctaattta gaatttccct gattgatgac
     4321 atccgatgca aaaggattgc tacgtgtcaa tttcaagtct tcaaaatcag ctgccgcctt
     4381 ctcagattct tctggtgtca tcagcatcaa aacttggtaa ataggttgat tcatcaggtg
     4441 aagcaggtcc tcttcctttt ggggaacaac cttgctgacc atgcgattaa aagactgact
     4501 caccgtccga gttaaaacag agggaacgaa gcgactaatt cgttgggaaa aagaacccag
     4561 accaaaggac atgattttag aacccaacat ggcatccttg gtccctaagg caatctccgt
     4621 gccctctttt ttagcatagc taattagatg gcgcaaatgt aacttggaaa tagggctcgt
     4681 gaacaagact ctgtctttac taaagatata ctggccatta taggttaccg caaaatccag
     4741 atccaaatcg tccatcaatt ccttaacaaa aaaaggtcct cgccctgtcg ctacgccaac
     4801 tagtacccct tgttctttga caatcttaat cgcatcctta gtggatttca aaacactctt
     4861 gcgattgttg accaaggttc catcgatatc aaaaaaaaca gctttgactt ccatcctatc
     4921 ccaatctccc cttttgtgat acaatgatta taccacattt cagaaagagt gagtaaatca
     4981 tgcctaagaa aatccttgtt ttacatacgg gtggaactat ttccatgcag gccgatgctt
     5041 ctggcgctgt tgtgacgagt tcagataatc ccatgaacca tgtgtccaac ccacttgaag
     5101 gaatccaagt ccacgccttg gactttttta accttccaag tccccatatc aaacccaaac
     5161 atatgctggt cctctaccag aaaattaaag aggaagcaga taactacgat ggagtggtga
     5221 tcacacacgg aaccgatact ttagaggaaa cagcctattt ccttgatacc atggaagttc
     5281 cccatatgcc tatcgttcta acaggagcca tgcgtagctc caatgaactc ggtagtgatg
     5341 gtgtttataa ttacctaagt gctttacgag tggccagcga tgacagggct gctgacaaag
     5401 gagttttggt cgttatgaac gatgaaatcc acgctgccaa gtatgtcacc aaaacacata
     5461 cgactaatgt cagcaccttc cagactccaa cacatggccc ccttggtctc atcatgaaac
     5521 aggaaatcct ctacttcaaa acagctgaac ctcgtgttcg ctttgacctt gatcacatac
     5581 aaggtttagt ccctatcatc tcggcttatg ctggtatgac agatgagctg attgatatgc
     5641 tggatttaga acacttggac ggtttgatta tccaagcctt cggagctggt aatattccca
     5701 aagaaacggc tcaaaaatta gaaagccttc tgcaaaaagg aattccagtc gctctggtat
     5761 cacgatgctt taacggtatt gccgagcctg tttatgccta ccagggtggg ggcgtacagt
     5821 tgcaaaaagc aggcgttttc tttgttaaag aactcaacgc ccaaaaagct cgcttgaaac
     5881 tcctcatcgc cctcaatgcc ggactaacag gacaggcttt gaaagactat atggaaggct
     5941 aatactcttc gaaaatctct gcaaaccacg tcacgtcgcc ttaccgtatg tatggttact
     6001 gacttcgtca gtttcatcta caacctcaaa acagtgtgtt gcgcagcctt taaccagccg
     6061 cctagtccgc tctatggtat tcattaagtc aacatctctt gtttaagagc acaaaatcag
     6121 gaaatcttct cgattccctg attttttcta tttacgtttt cgtgttgagc tacgttctgt
     6181 caaaccatga ggtaagagaa cttcacgttc ttccaactct tccttatgca taatcttggt
     6241 caacatacgc atactaatgg caccaaggtc ataaagaggt tgggcaatcg ttgtcaagtt
     6301 tggacgggta aagcgtgaga tttgtgaatc atcactagta ataatttcaa aatcttctgg
     6361 cacagaaaca cccttatcag ccaaaccgtt caagactcct gctgccaact catcacctgt
     6421 cacaactgct gcagttgcat ttgatgaaat caaacgctct gctaaggcgt aaccatcatc
     6481 atagctatat ttagattcaa ataccaaacc ctcactataa gtgattcctg cttttttcaa
     6541 ggtttccttg tagccaacta aacgaacctt accattgatg tcatccacta gcggaccgct
     6601 aacgaaagca atacgctcat tttctttaac aaggtaactc actgcatcaa ttgttgcttg
     6661 cttatagtca atattgacac ttggcaactg gtgctcaaca tcgacagttc ctgcgagaac
     6721 aatcggagta cgtgaacgcg aaaattctga gcgaatttta tctgtcaagt gataacccat
     6781 atagataatg ccatctacct gctttgaaaa gagggtattg acaacagaaa cttctttctc
     6841 gttatcttca tcgctattag ctaggacaat attgtacttg tacatttctg caatatcatc
     6901 aatcccctta gccaaactcg aaaaataacc attggtaata tttggaatca cgacaccgac
     6961 agtggttgtc tttttacttg caagaccacg cgcaactgca tttggacgat aatccaaacg
     7021 atcaattacc tctagcactt ttttacgggt attctctttt acatttttat tgccattgac
     7081 cacacggctg accgtcgcca tggaaacacc tgcttcacga gcgacatcat aaatggttac
     7141 tgtatcatct gcattcattc cttttcctgt cctttctatc tcacacattc ttttacaagt
     7201 agaggtgctg attgaagctc tatatctact tacaaaagtg aagatgtgaa aatttcgttt
     7261 tcatatttct acttattcca ttctatcact aattgtaaac actttcaagt gttttttgaa
     7321 gattgattga aaaaatttca tagaaaacct aggtttagct ccttgctacc accttagact
     7381 aaacaaaaag gaggaaacta agccctccta aagttatagt aaaatgaaat aagaacagga
     7441 taaatcgatc aggacagtca aatcgatttc taacaatgtt ttagaagtag aggtgtacta
     7501 ttctagtttc aatctactat aggtattgtt ccattcacta ccgtcaattt tagcacatag
     7561 tcttcataaa atattatatc atcataacca accagattct tttgcgatat tagctgcctc
     7621 tgttcgatta ccagcatcca gttttgaaag aatattggtg acatagtttc gaatagttcc
     7681 gtttgagagg taaagctgat ctgcgatttc ttggttggat aagccccggg cgattccctt
     7741 taagacagca atctcttgtt ctgtcaacgg attgggacgg gtcatcacca cttccatcaa
     7801 ttcaggcgaa tactccttgc gtccttcgag gacggtgtgc aaggtttgca tgaggtctgc
     7861 aatgcttcgt tcctttaata cataagcatc tactccagcc ttgaccgcac gttcaaaata
     7921 ccctgggcgc ttgaaggtcg tcactacaac cacctttgtt tcgagctttt ctgctcgtat
     7981 ccactccaag acttcgagtc ctgtcttaac aggcatttct acgtcaagga tggcgatatc
     8041 tacagactcc ttttctaata gttgaattgc ttcttgacca ttcttggctt gtaagacaga
     8101 ctctacatct gcttgaaagg caagcaactg gcacatggca tctcgcaaca tactttgatc
     8161 ttctgcgact aatactttca tctactttct ctccttataa ggtagtcgaa cttgcacttc
     8221 cgttggatgt ttctgactga ttacacttac ttctcctgaa aatggagaaa cacgatctcg
     8281 gactgtatgg agctcatctc cttttagaaa agcaaagccg cagccatcat cacttactgt
     8341 taaaatgagt tctttctctg cccgttctaa tttcaggtag gccttcgacg ctttggcatg
     8401 tttgataata ttggtcacca actcaagcaa aatcatggaa gccgttgact ccaattcttg
     8461 agtaagacta gcagtatcta gttggttatc cgtttccacc tcaattccag caatttctaa
     8521 catctttttc acagtctcta gttcggatgt caaagttcta gacttaagat tttccacaat
     8581 ggttcgcact tcattcatgg aatccttact gatctggtga atttctttta attccttttc
     8641 cacctgtgga taagcctcca tctgaaataa ctgcaaggct aaatctgtct tgacactcaa
     8701 catagcaaag gtatgtccca agctatcatg caaatcctga ccgatacgac tgcgttcatt
     8761 ttcagcaagc aatagattta tctgggcatt ttgcttgacc tgagcttctt tcaaatcctc
     8821 cacaatacga atccgaacca agccaaaagt cattaaatcg acaaaagcaa gaattacaag
     8881 tagatagaat agaaactcaa cttcgattct ctgaaaaatc aacagttggc ccacaacaag
     8941 gacttgagca agaagaaaag tccagacatg taaagacttt aaaccaccta cgctgaaatg
     9001 ataacttaag agattggata ggaaaaagaa aaaccagata taattaacag caacaaaggc
     9061 agtattccca actacataag tcagcatgag gccccaatat agccaagata ggcgctggct
     9121 cttagttgtt aaaacaccca aatacgccac tacaaataga atatcaatca ataaatgcca
     9181 gctaggaatc tccccagtca ctacaggtag gatggggaaa atcataaaaa ttaaactggc
     9241 ccaatacata tagtctatgc tttttagtct ttcaagcatt aagcattctc cttatgacct
     9301 tgaagataaa tggtcaaacc aaacaaaact gctgaaaaaa caagtatata aactgtggct
     9361 gatagattga tgccaccctc gtttaagaag gttttgagca actccatcaa ctgataagtt
     9421 ggtaggcact tcccgattgc ttgcatccag tctggaaata aagagatggg catccagagt
     9481 ccgcctaaaa cagccaagcc tagatagaga agattgccca cgacagacat caactgacta
     9541 gaaggcaaga gtgtcaaggt caagccaagc gctacaaagg caacacttcc tactattagc
     9601 aagaacgcag ccccaatcca gcttcctaga ggcatatcca cacctcttac aaaatgccca
     9661 actgagaaaa caaccagaat tgataccaaa taatcaacca tcatacttgt tatctttgat
     9721 agataatatt ctaccatatt tacaggggta tggcgcaatg ttttctgcca gttgttgatt
     9781 ttatcagtat gtaagacagc tgggaatgaa aacatagctg tcgacatcat ggaaaaggct
     9841 gtcatggaga tgaggtaatc acgcataaaa ttcgcgagtt cacctggtgt gtcctgatag
     9901 ataccagaaa aaaataaata gaaagccgtc ggcatcccta ccgacaatag ataatagatt
     9961 aattgtcgtt tggtcaataa aaattctatc ttactaagtg ctatccatcg tttcatctta
    10021 gttatctccc ttttgtgttt cttcaaagat tgtattcaac aaactacgat tattaacttc
    10081 gatttcttgc atcctacatc ctgcttgggc taatagttcc cagaaagcat ctgcttctcg
    10141 agtgactact tgtagagcat cctgtttttg tgaccagttt tcaaccaagt tagactgctc
    10201 aatgacttcc ttgtatgcca gaggaaggat aaaatgcttt tcaattccct cactacgcat
    10261 agctagaggc gtcgtatcac gaatcaactc tcccttattt aaaaccaaaa tccggtcagc
    10321 cgtatgctct acctcttcaa tataatgaga cgaatagaga atcgtgactc cttgcgcttt
    10381 taggtcccga acgatttccc aaaagcgttg acgagttgaa gtatccatgg cagcagttgg
    10441 ttcatctaaa aagacaagct ttggtcgccc aatcaaggtc aagacaaaag agaagagacg
    10501 cttttgcccg cctgacaatt tttctgcgaa ttgctctttt tgttgctggt caaactgcaa
    10561 tagttgatcg atttcctgat cgctcaagga atttggatag atacgttgaa agaaagcaat
    10621 caactctttg acctttaatt tctgaacgat gacattttct tgaggcagat aacctctaat
    10681 atagtctaac tgagaactcg tcactgacaa gccttggatg gatacttgac cgcttgtgac
    10741 cagtttatct ccaagcagac agtccaagag tgtggtcttc ccagcaccat tgggcccaat
    10801 caaggcgacg cattcacctt cagctacctc aaaggaaata cccttcaaaa tagccttgcc
    10861 cttgatgttt ttatttaggc tttctacctt aatcatattc atgatattct cctttcaacc
    10921 actccattct cataaggaaa acgacgaaaa tcataaatcc aaaccccaaa gcaccacgaa
    10981 tgaattggcg aagcaaggtt tggtcaaacc aacctgtaaa catttccact aaccatacca
    11041 agagtgacag gccgataaag aaatagatga tccctctctt cattcctcaa actccttttt
    11101 cacatctccg actaatttca aaccttctct aacaagccaa gacatcattc caaagccagc
    11161 aaagagctcc caaggaaaat gatagaaact ctcatccaat cccgaaaaca tgagttaggt
    11221 cataactcct gctactacta aactcactgc gataatcatt ttatttctca tctcttcttc
    11281 ctccatttca tactacaatt atagtctttt gaaatcagag gagacagaag cttctgtcac
    11341 tagaaaatat gacaaatgtc ataaaaaatt ctgttcaaaa caagcaagat acactataca
    11401 ataaaacaca atcagaaaaa tctaaggcaa cttcctcaaa agagatatca aacccaattc
    11461 acaccataat gtaaactaat acttatttaa aatcaaaaag agtagaaatt tttatcagac
    11521 aaacac
//
LOCUS       DAVLBE010000058        11077 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.058, whole genome shotgun sequence.
ACCESSION   DAVLBE010000058 DAVLBE010000000
VERSION     DAVLBE010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11077)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11077)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11077
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.058"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            40..762
                     /locus_tag="VXB91_001693"
     CDS             40..762
                     /locus_tag="VXB91_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEV0471107.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKAKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
     gene            759..1607
                     /locus_tag="VXB91_001694"
     CDS             759..1607
                     /locus_tag="VXB91_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEV0471108.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            1639..2568
                     /gene="psaA"
                     /locus_tag="VXB91_001695"
     CDS             1639..2568
                     /gene="psaA"
                     /locus_tag="VXB91_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HEV0471109.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            2691..3182
                     /gene="tpx"
                     /locus_tag="VXB91_001696"
     CDS             2691..3182
                     /gene="tpx"
                     /locus_tag="VXB91_001696"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HEV0471110.1"
                     /translation="MVTFLGNPVSFTGKQLQGGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGRDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(3278..5986)
                     /locus_tag="VXB91_001697"
     CDS             complement(3278..5986)
                     /locus_tag="VXB91_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEV0471111.1"
                     /translation="MIKRKTYWKDLIQSFTGSKGRFLSILILMMLGSLALVGLKVTSP
                     NMEATANAYLTTAQTLDLAVMSNYGLDQADQEELKQTEGAEVEFGYLTDVTMDNGQDA
                     IRLYSKPERISTFQLRKGRLPQSDKEIALATHLQGQYSVGQEISFKEKEEGHSSLKDH
                     TYTITGFVDSAEILSQRDMGYAGSGSGTLTAYGVILPSQFDQKVYNIARLKYQDLAGL
                     NAFSSAYEEKSKQHQEDLEQTLSDNGKVRLQLLKKEGQESLDKGQETLDKAQTNLQEG
                     KRRLAAAQARIQAQESQLALFPQVQREQASAQLTQAKQELGKEEDKLKQAEQNLAQEK
                     EKLEKHQQVLDDLAEPRYQVYNRQTMPGGQGYLMYSNASSSIRAVGNIFPVVLYAVAS
                     MVTFTTMTRFVDEERTHAGIFKALGYRSKDIITKFLLYGLVAGTVGTALGSILGHYLL
                     ASVISSVITKGIVVGETQIQFYWTYSLLALVLSWLASVLPVYLVAWRELHAEAAQLLL
                     PKPPVKGAKILLERIGFIWRRLSFTHKVTARNIFRYKQRMLMTIFGVAGSVALLFAGL
                     GIQSSVAGVPSKQFQQIQQYQMLVSETPSATNQDKVELAEVLKGQEILAYQKIYSKTL
                     DKDFKGKAGLQNITLMMIEKEDLTPFIHLQHHQQELTLKDGIVITAKLAQLAGVKVGQ
                     TLEIEGKELKVAAITENYVGHFIYMSQASYEQLYGQLPQANTYLVSLRDTSATSIESQ
                     AGLLMNQSAVSSVVQNASAIRLFDSIASSLNQTMTILVIVSVLLAIVILYNLTNINVA
                     ERIRELSTIKVLGFHNNEVTLYIYRETIVLSLVGIVLGLVAGFYLHQFLIQMISPATI
                     LFYPQVGWEVYVIPVAAVSIILTLLGFFVNYYLRKVDMLEALKSVE"
     gene            complement(5988..6689)
                     /locus_tag="VXB91_001698"
     CDS             complement(5988..6689)
                     /locus_tag="VXB91_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0471112.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANCDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDALNPDQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIQMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            complement(6939..9350)
                     /locus_tag="VXB91_001699"
     CDS             complement(6939..9350)
                     /locus_tag="VXB91_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HEV0471113.1"
                     /translation="MIRNKKQDYVLAYKQPVSTTYMGWEEEALPIGNGSLGAKVFGLI
                     GAERIQFNEKSLWSGGPLPDSSDYQGGNLQDQYVFLAEIRQALEKRDYNLAKELAEQH
                     LIGPKTSQYGTYLSFGDIHIEFSQQGTTLSQVTDYQRQLNISKALVTTSYVYKGTRFE
                     REAFASFPDDLLVQRFTKEGAETLDFTIELSLTCDLASDGKYEQEKSDYKECKLDITD
                     SHILMKGRVKDNDLRFASYLAWETDGDIRVWSDRVQISGASYANLFLAAKTDFAQNPA
                     SNYRKKLDLEQQVIDLVDTAKEKGYTQLKSRHIEDYQALFQRVQLDLEANVDAFTTDD
                     LLKNYKPQEGQALEELFFQYGRYLLISSSRDCPDALPANLQGVWNAVDNPPWNSDYHL
                     NVNLQMNYWPAYVTNLLETVFPVINYVDDLRVYGRLAAVKYAGIVSQKGEENGWLVHT
                     QATPFGWTAPGWDYYWGWSPAANAWMMQTVYEAYSFYRDQDYLREKIYPMLRETVRFW
                     NAFLHKDQQAQRWVSSPSYSPEHGPISIGNTYDQSLIWQLFHDFIQAAQELGLDEDLL
                     TEVKEKSDLLNPLQITQSGRIREWYEEEEQYFQNEKVEAQHRHASHLVGLYPGNLFSY
                     KGQEYIEAVRASLNDRGDGGTGWSKANKINLWARLGDGNRAHKLLAEQLKTSTLPNLW
                     CSHPPFQIDGNFGATSGMAEMLLQSHAAYLVPLAALPDAWSTGSVSGLMARGHFEVSM
                     SWEDKKLLQLTILSRSGGDLRVSYPDIEKSVIKMNQEKIKAKCMGKDCISVATAEGDL
                     VQFYF"
     gene            complement(9403..10095)
                     /locus_tag="VXB91_001700"
     CDS             complement(9403..10095)
                     /locus_tag="VXB91_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HEV0471114.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIKFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            complement(10146..10436)
                     /locus_tag="VXB91_001701"
     CDS             complement(10146..10436)
                     /locus_tag="VXB91_001701"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0471115.1"
                     /translation="MIESIRTYADYIDLYKNIFDDYFTKAEEGFKGTAMENNDSFTKL
                     KESTQKLFDAQKKRLNNEDRIETTKNNVIAKHCQTVLSFLVLTSFFVKNCVK"
     gene            complement(10630..11010)
                     /locus_tag="VXB91_001702"
     CDS             complement(10630..11010)
                     /locus_tag="VXB91_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0471116.1"
                     /translation="MKLKTLALISGIVGLVGGILLLIGPFVLLGTAVNTVATTLNGGA
                     TAGAFSGVALLLNALKIANLVLGIIAIVYYKGDNRVGAAPSVLMIVFGGVSLIPFLGW
                     VGGILVIIGGSLFLATLKKFKSEE"
BASE COUNT         3245 a         2532 c         2063 g         3237 t
ORIGIN      
        1 tttttaatgt atattaagag acaggaggaa tacaagttta tgatacgtat cgaaaacctc
       61 agtgtctcct acaaagaaac gttggcactt aaggatattt cactagtgct ccatggacca
      121 acaattaccg gcatcattgg tccaaacggc gctgggaaat caacactatt aaaaggtatg
      181 ctgggaatta tcccacatca aggtcaggca tttctcgatg acaaggaagt taaaaaatcc
      241 ttacaccgaa ttgcctatgt cgaacaaaaa atcaatatcg actacaactt tcccatcaag
      301 gtcaaggaat gcgtctcgtt aggactattt ccctctattc ctctctttcg aagtttaaag
      361 gctaaacatt ggaagaaagt gcaagaggcc cttgaaatcg tcggcctagc tgactacgct
      421 gaacgtcaaa ttagtcaact gtctggaggt caattccagc gggtcttgat tgccagatgt
      481 ttggtgcagg aagccgacta tatcctcttg gatgaaccct ttgctgggat tgactctgtc
      541 agtgaggaaa tcatcatgaa tacgctgaga gatttgaaaa aagctgggaa gacggttctc
      601 atcgttcacc acgacctcag caagattccc cactacttcg atcaagtctt acttgtcaat
      661 cgagaagtga ttgcctttgg tccaacaaaa gaaactttta ccgaaaccaa tctaaaagaa
      721 gcttacggta atcaactctt tttcaatgga ggtgacctat gattgcagaa tttatcgatg
      781 gattgcaaaa attccatttc ctacaaaatg ccttgataac agctattgtc gtcgggattg
      841 tagctggagc tgtgggatgt ttcattattc tacgcgggat gtcactcatg ggagatgcca
      901 tttcacatgc tgtcttacca ggtgtagccc tctccttcat cttgggcctt gacttcttta
      961 tcggagccat tgtctttgga ttgctagctg ccatcatcat tacctacatc aaaggaaact
     1021 cgattatcaa aagcgatacc gccatcggca ttaccttttc ttctttctta gccctcggta
     1081 tcatcttgat tggtgtcgct aaaagttcaa ctgacctttt ccatatcctt tttggtaata
     1141 tcctggccgt ccaagatacg gatatgttta ttactatggg tgtgggggca gccatcctct
     1201 tgttaatctg gattttcttc aagcaactct tgataacttc ctttgatgaa ctcttggcta
     1261 aagccatggg aatgcctgtc aatttctatc actaccttct catggtactc ctgactctcg
     1321 tgtctgtgac agccatgcaa agtgtcggaa ctatcctgat tgtagccatg ctgattaccc
     1381 cagctgcaac tgcttatctg tatgctaata gtctgaaaag catgattttc ctttcctcaa
     1441 ccttcggagc tactgcttca gttttgggac tctttattgg ctatagtttt aatgttgcgg
     1501 caggttctag tatcgtgctt acagctgcta gtttctttct cattagcttc tttatcgctc
     1561 ccaaacaacg atatttgaaa ctgaaaaata aacatttgtt aaaataaggg gcaaagccct
     1621 aataaattgg aggatctaat gaaaaaatta ggtacattac tcgttctctt tctttctgca
     1681 atcattcttg tagcatgtgc tagcggaaaa aaagatacaa cttctggtca aaaactaaaa
     1741 gttgttgcta caaactcaat catcgctgat attactaaaa atattgctgg tgacaaaatt
     1801 gaccttcata gtatcgttcc gattgggcaa gacccacacg aatacgaacc acttcctgaa
     1861 gacgttaaga aaacttctga ggctgatttg attttctata acggtatcaa ccttgaaaca
     1921 ggtggcaatg cttggtttac aaaattggta gaaaatgcca agaaaactga aaacaaagac
     1981 tacttcgcag tcagcgacgg cgttgatgtt atctaccttg aaggtcaaaa tgaaaaagga
     2041 aaagaagacc cacacgcttg gcttaacctt gaaaacggta ttatttttgc taaaaatatc
     2101 gccaaacaat tgagcgccaa agaccctaac aataaagaat tctatgaaaa aaatctcaaa
     2161 gaatatactg ataagttaga caaacttgat aaagaaagta aggataaatt taataagatc
     2221 cctgctgaaa agaaactcat tgtaaccagc gaaggagcat tcaaatactt ctctaaagcc
     2281 tatggtgtcc caagtgccta catctgggaa atcaatactg aagaagaagg aactcctgaa
     2341 caaatcaaga ccttggttga aaaacttcgc caaacaaaag ttccatcact ctttgtagaa
     2401 tcaagtgtgg atgaccgtcc aatgaaaact gtttctcaag acacaaacat cccaatctac
     2461 gcacaaatct ttactgactc tatcgcagaa caaggtaaag aaggcgacag ctactacagc
     2521 atgatgaaat acaaccttga caagattgct gaaggattgg caaaataagc ctctgaaaaa
     2581 cgtcattctc atgtgagctg gcgttttttc tatgcccaca tttccggtca aatcattgga
     2641 aaattctgac tgtttcagat acaatggaag aaaaaagatt ggagtatcct atggtaactt
     2701 ttctcggaaa tcctgtgagc tttacaggta aacaactaca aggcggcgac aaggcgcttg
     2761 atttttctct tactacaaca gatctttcta aaaaatctct ggctgatttt gatggcaaga
     2821 aaaaagtcct gagtgtcgtt ccttctatcg atacaggcat ctgctcaact caaacacgtc
     2881 gttttaatga agaattagct ggactggaca acacggtcgt attgactgtt tcaatggacc
     2941 taccttttgc tcaaaaacgt tggtgcggtg ctgaaggcct tgacaatgcc attatgcttt
     3001 cagactactt tgaccattct ttcgggcgcg attatgccct cttgatcaac gaatggcacc
     3061 tattagcacg cgcagtcttt gtcctcgata ctgacaatac gattcgctac gttgaatacg
     3121 tggataatat caattctgag ccaaacttcg aagccgcaat tgcagctgct aaagccctat
     3181 agaaaaaatc ctctgtcaca aagagttccc tgctctttga aacggaggat ttttgaatat
     3241 taataaatag aagttcaatc agctaaaaat aactacctta ctctacagat ttcagggctt
     3301 ctaacatatc aacctttctc agataataat tgacgaagaa accaagcaag gtcaaaatga
     3361 tgcttactgc tgccactggg attacataga cttcccagcc tacctgcgga taaaagagaa
     3421 tagtcgcagg cgaaatcatt tgaatcaaaa attggtgtaa atagaaacca gctaccagac
     3481 caagtacgat tcccacaagg gacagcacaa tcgtctcacg gtaaatgtag agggtgactt
     3541 cattattatg aaaaccgaga accttgatag tggagagttc acggattctc tcagctacgt
     3601 tgatattggt cagattgtaa aggatgacaa tagctaatag aaccgatacg atgaccaaga
     3661 tggtcatggt ctgattgagt gagctagcga tagagtcgaa gagtcgaatg gctgaagcat
     3721 tttggacaac gctggacacc gcagattgat tcataagcaa gcccgcctga ctttcgatac
     3781 tagttgcact ggtatccctt aatgagacca gataagtgtt ggcttggggt agctgtccgt
     3841 aaagttgctc atagctagcc tgactcatat aaataaagtg accaacgtag ttctcagtaa
     3901 tagcagcgac ctttagttcc ttaccttcaa tttctaaagt ctgcccaacc ttgacacctg
     3961 ccagctgggc gagtttagct gtaataacga tgccatcttt taatgtcagc tcctgctgat
     4021 gatgttgaag atggataaag ggagtcaaat cttccttctc tatcatcata agagtaatgt
     4081 tttgaagacc agccttgcct ttgaaatcct tgtctagcgt tttagaatag attttctggt
     4141 aggctagtat ctcctgccct ttcaacactt ctgctagctc taccttgtcc tgattggtcg
     4201 cactaggagt ttcagagaca agcatctgat actgttggat ttgttgaaac tgtttagacg
     4261 gaactcctgc tacagaagat tggattccca aacctgcaaa gagcagagct acagaacctg
     4321 ccacaccaaa gattgtcatc aacattctct gcttataacg aaagatgttg cgggctgtta
     4381 ccttatgagt aaaactgaga cgacgccaga taaaaccgat acgctccaat aagattttag
     4441 ctcctttgac aggaggttta ggaagtagaa gctgggctgc ttcggcatga agttccctcc
     4501 aagccaccag atagactggt aacacactcg ccaaccaact caagacaaga gctagtaagc
     4561 tataggtcca atagaactga atctgggttt ctcccaccac tatgcctttt gtaatgacac
     4621 ttgaaattac actggctagc aaataatgac caagtatact acctagagcc gttccgacag
     4681 tcccagctac tagtccataa aggagaaact tggtgataat atccttacta cggtaaccca
     4741 aggccttaaa aatccctgca tgagttcgct cttcgtctac aaagcgagtc atggtcgtaa
     4801 aggtcaccat ggatgctacg gcataaagta ccacaggaaa gatattgccc actgctcgaa
     4861 tactggatga agcattgcta tacataagat agccctgacc acctggcatg gtctgacgat
     4921 tatagacctg ataccttggc tccgccaaat cgtccaagac ttgctgatgt ttttctaatt
     4981 tttccttttc ttgggctaga ttttgttcag cttgctttag tttgtcctct tccttgccca
     5041 attcctgctt ggcttgggta agttgagcac tagcctgctc tctctgaact tgaggaaaca
     5101 aggctagttg actttcttga gcctgtatac gagcttgagc agctgctaaa cgacgcttgc
     5161 cttcctgcaa attagtctga gccttgtcaa gggtctcttg ccccttgtct agagactctt
     5221 gtccttcttt tttcaaaagt tgcagacgta ccttgccatt atctgataaa gtttgttcaa
     5281 ggtcttcctg atgttgcttg gatttttctt cataagctga tgaaaaggca tttaaacctg
     5341 ctaaatcttg atatttcaaa cgagctatat tgtagacttt ctgatcaaac tgactaggta
     5401 aaatcacccc ataggctgtc agagtcccac ttccacttcc tgcgtagccc atatctcgct
     5461 gggagaggat ttcagccgaa tccacaaaac cagtaatggt ataagtatgg tcttttaaag
     5521 aggaatgacc ctcttctttt tctttaaaac taatctcctg tcccacgctg tattggcctt
     5581 gcaaatgagt ggccaaagcg atttccttgt ctgactgagg aagtcgtccc tttcttagct
     5641 gaaaggttga aattcgctct ggtttggagt acagccgaat ggcatcctgc ccattatcca
     5701 tagtcacatc tgtcaaatag ccaaactcga cctctgcgcc ctccgtctgt tttagttctt
     5761 cttggtctgc ttgatccaag ccatagttag acatgactgc caaatccaag gtttgagcag
     5821 ttgttaaata agcattagct gtcgcctcca tgttgggact ggttactttg aggcctacta
     5881 aggctagaga tcccaacatc atcaggatca agatggataa aaaacgcccc ttggagcctg
     5941 tgaaggactg aattaagtcc ttccaataag tttttcgctt gatcatgcta gtactccaaa
     6001 ctgtcaatat cctgaggatg ctggttgagc accacatcct tgacactggc atcgtgcatt
     6061 tgaatcacgc gatcagcaat gggcgccaaa gctccattat gagtcacgat gatcaccgtc
     6121 gctccctttt gacgagacat gtcttggaga attttcaaaa cctgcttgcc cgtctgataa
     6181 tccaaggctc cagtcggttc atcacaaagg agaattttag gatttttggc taccgcgcgt
     6241 gcaatggaga ctcgctgttg ctcccctcca gaaagctggg ctggaaagtt attgagacga
     6301 tgagccagac ctacatctgt caagacctga tcaggattca aggcatctgt cacaatttca
     6361 gaagccagtt ccacattttc cttagctgtc agattagaaa ctagattata aaactgaaaa
     6421 acaaacccca catcatttct acggtaattg gtgcgctggt gggaactata atccgcaata
     6481 ttaacaccat caatccagat ttccccttca tcattggtat ccattccccc aagaaggtta
     6541 agaactgttg acttgcctgc acctgaagca ccaaggataa taaccagctc ccccttttca
     6601 atctcaaaat tcacatcaca attggccaca atctccgtgt ccccaacctg ataacgcttg
     6661 taacagtgtt tcatctcaat ataagccatc agacccaccc tctatcaaac aaattatact
     6721 cctcgaaaat ctctcttcaa accacgtcag cttccatctg caacctcaaa acactgtttt
     6781 gagcaacctg cggctagctt cctagtttgt gctctttgat tttcattgag tattacttcc
     6841 tattatcatt ataacgtttt ttcaactagt tgaaaactgc ttatattctt aaatccttat
     6901 taaaaggcag tttcaaatta ctgccttata acatcttctt aaaaataaaa ttgaacaaga
     6961 tcaccttctg ctgttgccac cgaaatacaa tctttcccca tgcatttcgc ttttattttt
     7021 tcttgattca ttttaatcac actcttctca atatctggat aagaaactcg caaatctcct
     7081 ccactccttg ataaaatggt caactgtaag agttttttat cttcccagct catgctcact
     7141 tcaaaatgtc cacgtgccat taagcctgaa acagaacctg ttgaccaagc atcaggtagg
     7201 gcagctagag gtaccagata agctgcatga gactggagta acatttctgc catgccacta
     7261 gtagcaccaa aattaccatc tatctgaaaa ggaggatggc tacaccaaag atttggcaag
     7321 gtggatgtct ttaactgctc tgccaataat ttatgggctc gattgccatc tcccaaacgc
     7381 gcccagagat tgatcttatt agccttggac cagcctgtgc cgccatctcc acgatcattg
     7441 aggctagcac gtaccgcttc aatatactct tgtcccttgt agctaaagag attgccagga
     7501 tagagtccca ctagatggga agcgtgccga tgctgggcct ccactttctc attttgaaaa
     7561 tactgctctt cctcctcata ccactccctg attcgaccag attgagtgat ttgcaaagga
     7621 tttagtaaat cagacttctc cttaacctca gtcaacaagt cctcatccag tcccaattcc
     7681 tgagcagcct gaataaaatc atgaaataac tgccaaatca gagattggtc ataagtattg
     7741 ccaatcgaaa tcggcccatg ttctggggaa taagacggag aagacaccca acgctgcgcc
     7801 tgctgatcct tatgtaaaaa ggcattccaa aaacgaaccg tttccctcaa catgggataa
     7861 attttctccc tgagatagtc ttggtcccta taaaatgaat aggcttcata aacggtttgc
     7921 atcatccacg cattggcagc tggtgaccaa ccccaatagt aatcccaacc aggtgccgtc
     7981 caaccaaagg gagtcgcttg agtatgaacc aaccaaccat tctcctcacc tttctgagag
     8041 acgattcctg catactttac agccgctaga cgaccataga cacgcaaatc atctacatag
     8101 ttgatgactg gaaagaccgt ctctaggaga ttggtaacat aggctggcca ataattcatc
     8161 tgcagattga catttaagtg atagtccgaa ttccaaggag gattgtcgac cgcattccag
     8221 actccctgta ggttagctgg tagagcatct gggcagtctc tggacgaact aatcaataaa
     8281 taccgtccat actggaagaa cagctcctcc aaagcctgcc cttcttgtgg cttataattt
     8341 tttaacaaat catctgtagt gaatgcgtca acattagctt ccaaatccaa ttgaacacgc
     8401 tggaataagg cttggtagtc ctcgatatgc cttgatttca attgggtata gcccttttct
     8461 ttagctgtgt ccaccaagtc tatcacctgt tgctctaaat ctagtttctt gcgataattg
     8521 ctagcaggat tttgggcaaa atccgtctta gcggccaaga agagattggc ataactggct
     8581 cctgatatct gaaccctatc tgaccaaact ctaatatctc catccgtttc ccaagctaga
     8641 taactagcaa accgcagatc attatcctta actcttccct tcatcaagat atgagaatca
     8701 gtaatatcca acttacactc cttgtaatca gatttttcct gctcatactt tccatcagaa
     8761 gccaaatcac aggtcaagga tagttctata gtaaaatcta gagtttccgc cccttcctta
     8821 gtaaaacgct gaaccaagag atcatctgga aaactcgcaa aagcttcacg ttcaaatcgc
     8881 gttcccttat agacataaga agtcgtcaca agtgccttac taatattcag ctgtctctga
     8941 tagtccgtca cctgagacaa agtcgtacct tgctggctga actcaatgtg aatatcccca
     9001 aaagacagat aggtcccata ttgactcgtt tttggcccaa ttaggtgctg ctcagccagt
     9061 tccttagcca gattgtaatc tctcttctcc aaagcctgcc gaatctcagc taaaaaaaca
     9121 tactgatcct gaagatttcc accctgataa tctgaactat caggaagtgg acctccagac
     9181 cagagacttt tttcattaaa ttgaatccgt tcagccccta taaggccaaa tacttttgct
     9241 cctaaagaac cattgcctat cggtaaagct tcttcttccc aacccatgta agtggttgaa
     9301 actggttgct tgtaggccag tacataatct tgttttttat tccttatcat acttccatac
     9361 taacataaaa agcctagaaa tcaattctag acttacaatt ttttattttc caaggtagta
     9421 ttcagaaacg acgttcaatt tttcgtcgaa ttcgaatacc aatggtggga agttagggat
     9481 ttccacgtcc atgatctcgt catctgacaa acctttgatg tgttttacaa gggcacggat
     9541 tgagttaccg tgagctccta cgaatacgtt tttaccatct ttaagagctg gagcgatttt
     9601 atcttcccag aatggaagag cacgttccaa agtcactttc aagttttcag catctgggat
     9661 tactgagtcg tcaagtgaag cataacgacg gtctgtgtga gctgagtgct catcatcacg
     9721 gtccatattt ggaggcaata catcgtatga acgacgccag atgtgaactt gctcatcacc
     9781 aaattgttca gcagcttcag ctttattttt accagtcaaa ccaccgtagt gacgttcgtt
     9841 caagcgccat gatttttcaa ctggaaccca caattggtca gaagcttcaa gagccaagtt
     9901 agttgttttg atagcacgtt tcaatactga agtgtaagct tggtcaaatt tgataccagc
     9961 ttctttgatc aatttaccag cgtcaatcgc ttgttgtgta cctttttcag acaaatcaac
    10021 atcagcccaa ccagtgaaaa ggttagcttt gttccattca gactcaccgt ggcgagcaaa
    10081 aaccaatttt accattagat ggattctcct ttaaattttc cgaggtttcc cctcgtttat
    10141 ctattctatt ttacacaatt tttcacaaaa aagctagtca aaaccaaaaa ggaaaggact
    10201 gtttgacaat gtttggcaat cacattgttt ttagttgttt ctattctatc ttcattattt
    10261 aacctttttt tctgcgcatc gaataatttt tgagttgact cttttagttt agtaaacgag
    10321 tcattatttt ccatagctgt gcctttgaaa ccttcctcag ctttagtaaa ataatcatca
    10381 aaaatatttt tataaagatc tatataatct gcataagtgc gtattgattc aatcacatcg
    10441 tctgttacaa ccggtgtatc gaaagtgatt gtttcttttg aactattgga tgttgctact
    10501 gtcttctcat cattacttgt tgaagtatcc tttgaacttt atgttccaca tgcaactaga
    10561 agaaaaagag ataatagagc tactcctata ccgataaact tttttgttct tttcatgcta
    10621 aaataccttt tattcttctg atttgaattt cttcaatgtt gcaaggaata gagatcctcc
    10681 gataataaca agaatccccc caacccatcc taagaatgga atgagactaa ctccaccaaa
    10741 aacaatcatt agtacagacg gagctgcacc tacacgatta tctcctttat agtaaacaat
    10801 agcaatgata ccaagaacaa gatttgcaat cttcaaggca ttcaagagta aggcaacacc
    10861 tgaaaaagcc cctgcagtag ctcctccatt aagagttgta gcaactgtgt ttaccgctgt
    10921 tcccaacaag acaaaaggac caataagaag taaaattcct cccacaagac cgacgatacc
    10981 actaattaaa gcaagtgttt ttaatttcat aataaaatct ccttttttat ttttttcaaa
    11041 taaaattgta tcatatttgc ttttaaaaaa agtattt
//
LOCUS       DAVLBE010000059        10915 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.059, whole genome shotgun sequence.
ACCESSION   DAVLBE010000059 DAVLBE010000000
VERSION     DAVLBE010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10915)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10915)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10915
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.059"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            408..569
                     /locus_tag="VXB91_001703"
     CDS             408..569
                     /locus_tag="VXB91_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0471117.1"
                     /translation="MNNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQEMKNSFD
                     MAKTQIETD"
     gene            661..1509
                     /locus_tag="VXB91_001704"
     CDS             661..1509
                     /locus_tag="VXB91_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEV0471118.1"
                     /translation="MSKEKIKVYLYTRVSTSIQIEGYSLGAQKSRMKAFAIYNDYEIV
                     GEYEDAGKSGKSIEGRIQFNRMMEDIKSGKDGVSFVLVFKLSRFARNAADVLSTLQIM
                     QDYGVNLICVEDGIDSSKDAGKLMISVLSAVAEIERENIRIQTMEGCIQKAREGKWNG
                     GFAPYGYKLEDGKLFINEEEAVAIRTIFDQYVNTTIGANGISKYLENHGIRKIPRQNG
                     KNPLFDAGLIRKILKNPVYNGKIAFGRRTLEKVHGTRNEYKQVEQDEYLISEGIHEAI
                     VSDEVW"
     gene            1555..2340
                     /locus_tag="VXB91_001705"
     CDS             1555..2340
                     /locus_tag="VXB91_001705"
                     /inference="COORDINATES: protein motif:HMM:NF024800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase zinc beta ribbon domain-containing
                     protein"
                     /protein_id="HEV0471119.1"
                     /translation="MNKGKDTRTHLLSGIVKCPICGVGMFGNKCIKKKKDGTKYKDFY
                     YYGCKHRQMIRGHKCTFSKQIREELLDDAVAEVIVKIVSNPKFASMMQEKINMKVDTS
                     EIEKEIDNYQKELRKSHSTKFKLIEEIDNLDVEDKHYKRRKQDLDDRLYRMYDKIDEL
                     ESSLIDAKAKKQTIEAEKLTGDNIYKVLIYFDKLYKVMNDVERRQLISALISEIQVYE
                     EKQSNGQWLKSITFKLPIIEENLNIGLDNDEQVECVSLLEKRS"
     gene            2608..3174
                     /locus_tag="VXB91_001706"
     CDS             2608..3174
                     /locus_tag="VXB91_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0471120.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGVEV
                     EYFNPKNIPDYMEIIFNGNIVPLSRFMFDPGENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKAYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
     gene            3497..3685
                     /locus_tag="VXB91_001707"
     CDS             3497..3685
                     /locus_tag="VXB91_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HEV0471121.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            3747..4562
                     /locus_tag="VXB91_001708"
     CDS             3747..4562
                     /locus_tag="VXB91_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEV0471122.1"
                     /translation="MVVYIRQSKLPSEVSINKYNAQVGAYLQGEEVILYQSFSEIKEL
                     TSEDIVVDYIMETRALLKMMGLNVPVHDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNETHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYGLS
                     PLKSINFHRARWKEMVKPYFEKMKFLKSNRMLFSKINMVDNQYKKHQNEQGGI"
     gene            4562..5416
                     /locus_tag="VXB91_001709"
     CDS             4562..5416
                     /locus_tag="VXB91_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HEV0471123.1"
                     /translation="MLGAIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGMWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRFYFGGYCR
                     EYEQSINDNPTECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQETVPQAIIAFL
                     ESRDFEDAIRNAISLGGDSDTLAAITCSIAEAAYGIPDWIKDKAYSYLDEPLKDVVRR
                     WENRIKAY"
     gene            5528..6412
                     /locus_tag="VXB91_001710"
     CDS             5528..6412
                     /locus_tag="VXB91_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEV0471124.1"
                     /translation="MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKVL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVVANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKED"
     gene            6575..8314
                     /locus_tag="VXB91_001711"
     CDS             6575..8314
                     /locus_tag="VXB91_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HEV0471125.1"
                     /translation="MELSAIYHGPESEYAYLYKDKKLHIRIRTKKGDIESINLHYGDP
                     FIFMEEFYQDTKEMVKITSGTLFDHWQVEVSVDFARIQYLFELRDTEGQNILYGDKGC
                     VENSLENLHAIGNGFKLPYLHEIDACKVPDWVSNTVWYQIFPERFANGNALLNPEGTL
                     DWDSSVTPKSDDFFGGDLQGIIDHMDYLQDLGITGLYLCPIFESTSNHKYNTTDYFEI
                     DRHFGDKETFRELVDQAHHRGMKVMLDAVFNHIASQSLQWKNVVKNGEQSAYKDWFHI
                     QQFPVTTEKLVNKRDLPYHVFGFEDYMPKLNTANPEVKNYLLKVATYWIEEFNIDAWR
                     LDVANEIDHQFWKDFRKAVLAKNPDLYILGEVWHTSQPWLNGDEFHAVMNYPLSDSIK
                     DYFLRGIKKTDQFIDEINGESMYYKQQISEVMFNLLDSHDTERILWTANEDVQLVKSA
                     LAFLFLQKGTPCIYYGTELALTGGPDPDCRRCMPWERVSSDNDMLNFMKRLIKIRKYA
                     SVIISHGKYSLQEINSDLVALEWKYEGRILKAIFNQSTEDYLLEKEAVALASNCQELD
                     NQLVISPDGFMIF"
     gene            8400..8717
                     /locus_tag="VXB91_001712"
     CDS             8400..8717
                     /locus_tag="VXB91_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000995815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0471126.1"
                     /translation="MNCRGHETRQRIVRDFEVQPKVHIKLLANQQKHSDAVATIEDEY
                     YVFIAESKIDGKKEVIQCCMGAARDFLELINHKGLPLFNPLVGDSHVNNRQEYDNTGS
                     GNL"
     gene            8763..9044
                     /locus_tag="VXB91_001713"
     CDS             8763..9044
                     /locus_tag="VXB91_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0471127.1"
                     /translation="MWLIILWNAKPDTPLFNFKDEVIKYKTYEPFESSIKRVNTTIKN
                     GSKGKTLTEMINGYRADNDIRDEICNFNILKNKIRDMKDQQGNTMESYF"
     gene            9489..9965
                     /locus_tag="VXB91_001714"
     CDS             9489..9965
                     /locus_tag="VXB91_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0471128.1"
                     /translation="MIGKNIKSLRKTHDLTQHEFARIVGISRNSLSRYENGTSSVSTE
                     LIDIICQKFNVSYVDIVGEDKMLNPVEDYELTLKIEIVKERGANLLSRLYRYQDSQGI
                     SIDDESNPWILMSDDLSDLIHTNIYLVETFDEIERYSGYLDGIERMLEISEKRMVA"
     gene            9965..10726
                     /locus_tag="VXB91_001715"
     CDS             9965..10726
                     /locus_tag="VXB91_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HEV0471129.1"
                     /translation="MEIQDYTDSEFKHALARNLRSLTRGKKSSKQPIAILLGGQSGAG
                     KTTIHRIKQKEFQGNIVIIDGDSFRSQHPHYLELQQEYGKDSVEYTKDFAGKMVESLV
                     TKLSSLGYNLLIEGTLRTIDVPKKTAQLLKNKGYEVQLALIATKPELSYLSTLIRYEE
                     LYIINPNQARATPKEHHDFIVNHLVDNTRKLEELAIFERIQIYQRDRSCVYDSKENTT
                     SAADVLQELFFGEWSQVEKEMLQVGEKRLNELLEK"
BASE COUNT         3868 a         1517 c         2273 g         3257 t
ORIGIN      
        1 aattttgtta catcaagata aatattttct gatggtcaaa ttttaaaaag attaataact
       61 ttcgataaat tttgaacctt aacaattgaa tagaccaaga caagacgtta attatttttg
      121 gagcgtaata acctatccgt caagatcttt cggctgaata attcggcaaa aaaagttctg
      181 ctaaacaaaa agaaagtgag cgataagtaa gagtttgaat atagggaggg ataccctatc
      241 cgctatgaag aaaatgagga taatgatact tctaaggttg aagccggctc atccggaata
      301 gaggcggagg tgagattcct atgttgctaa tccaaagcac ttgtcaatgt caaaaaactt
      361 aattaaacaa ataattatta gatataaaac tttagaggag gtatatattg aacaatgact
      421 ggaatggatt ggctgattta atagcaaatc tgattgcaaa atatgctggt gctttagatt
      481 tagataatct acccgatcca acgccagcaa aaaatcaaga gatgaaaaat agttttgaca
      541 tggcaaaaac acaaattgag acggactaat aaaagtgtta taatatactt gaaatgatag
      601 tccaaactta aattaaaaaa attatatatg atatagaaaa attatattga ggttaatact
      661 atgtcaaaag aaaaaataaa agtatacctc tatacacgag tatctacgtc aatacagata
      721 gaggggtatt cgttaggggc acaaaaatca cgaatgaaag cttttgctat ttacaacgat
      781 tatgaaattg ttggagagta tgaagatgcc gggaagtctg gcaagtctat tgaaggtaga
      841 atacagttca atcgaatgat ggaagatata aaatctggaa aagatggagt atcttttgtt
      901 cttgtgttta agttatcaag atttgcaaga aatgccgctg atgttctttc tacacttcag
      961 ataatgcagg attatggagt taatcttatc tgcgttgaag atggcattga ttcatctaaa
     1021 gatgctggga aactaatgat ttctgtttta tcagctgtgg ctgaaataga aagagaaaac
     1081 atccgtattc aaacaatgga aggttgcatt caaaaagcaa gggaaggaaa atggaatggt
     1141 ggctttgctc cgtatggata taaacttgaa gacggcaagc tgtttataaa tgaggaagag
     1201 gcagttgcaa taagaacgat tttcgaccag tatgtaaata ctacgatagg agccaatggg
     1261 atatctaaat acttagagaa tcatggaatt agaaaaatcc caagacagaa tggtaagaat
     1321 cctttgtttg atgcaggtct tataagaaag atattaaaga atcctgtata taatgggaaa
     1381 atagcatttg gaagaagaac tttagaaaaa gttcatggta caagaaatga atataagcag
     1441 gttgaacaag atgaatatct aatatctgaa gggatacatg aagctatagt ttccgatgaa
     1501 gtttggtaag ctgctcaggt taagctaaaa tctcaagcaa agaaatatga gcatgtgaat
     1561 aaaggaaaag atacacgcac acacttgctt tctggaattg taaaatgccc gatatgtgga
     1621 gtgggaatgt ttgggaacaa gtgtatcaag aaaaagaaag atggcacaaa gtataaagat
     1681 ttttattact atggttgtaa acataggcag atgataagag gtcataagtg tacattcagt
     1741 aagcaaatta gagaagaatt gttagatgat gctgttgcag aggtgattgt caagatagta
     1801 agtaatccga aatttgcttc tatgatgcaa gaaaaaatca acatgaaggt ggatacctct
     1861 gaaatagaaa aagaaataga taattaccaa aaggaattga gaaagagtca ttctacaaag
     1921 tttaagctaa ttgaggaaat agataattta gatgttgaag ataagcatta taagagaagg
     1981 aaacaggatt tagatgatag actatatcgt atgtatgaca aaatagatga attagaatca
     2041 tcactaattg atgcgaaagc aaagaaacag actattgaag ctgaaaagct tacaggagat
     2101 aacatatata aggttctgat ctattttgat aagctctata aagtcatgaa tgatgtagag
     2161 cgtaggcagt taatttcagc tttgatttct gaaattcaag tttatgaaga aaaacaatct
     2221 aacggacaat ggctaaaatc cattactttt aagctaccaa ttatagaaga aaatctcaac
     2281 ataggtttgg acaatgatga acaagttgaa tgtgtaagtt tattagagaa acgtagttaa
     2341 tcctcaaaag gttccccgaa ccttttgagt cccactgacg catcacgctg aggcggtatc
     2401 gctgtttgta cgagttgaag catcagcaaa gtaaaagtag atgttcagcc aatgcgacga
     2461 ggtgagaccg aaggtcgata aggtgtgttc tgggtatagg actcgtaaag taagtaggaa
     2521 atatgatgag atgatacaga gagcctgaat tggtcaggtg acgtgcttat ttacattagc
     2581 ctgataatga aaatggagag attatcgatg gttatattgg aattgtacca aaatgattat
     2641 tctaaagatt tagtagcatt tgattccata gaagatggga aagcctttgt agctcaaatc
     2701 ccgggataca ctctggaaac agaagatggt gttgaagtgg agtattttaa tcctaaaaac
     2761 ataccggatt atatggaaat tatttttaac ggaaatattg ttcctttatc tagatttatg
     2821 ttcgatcctg gggaaaatgt aaacattatt tggaaagaga tttcaaattt atccctcaaa
     2881 aatgatagag tgatcgaagg atattcaaaa attgatgcat atgtcgttaa caaccatgaa
     2941 gttaaagcct atgtcgaaac aagagaaacg aactatcgta aagcaaaaga cttcttagaa
     3001 agccgcggat atgaaatcga cagaagcttt ttcggaagtg aagacggtga agcgattctt
     3061 tacagaaaaa aagggatcga agtttggcat ttcttgtgtc acttagaccc aatgtttgta
     3121 gagattgaag atgtagaagg atatgttaaa gaagaagttg gagagattca atagtcaacc
     3181 aaagttcctt gtgagtatat acctttgcta gtaaaagagt caaaacgtta taacgaaggg
     3241 gggggaagaa aacccttgag tgtaagtctt tttcttgttt agagggaaag tattagagta
     3301 gccgctcata atttatacta gatttgataa ctgatttgag acagatttta tttctataaa
     3361 tattgtgaaa attttttaat accaaagatt taaagttact gtgttaaaaa tcctctccac
     3421 ttttaaacta atgtattata aaagccagtt gacacaagtg ttacacctgt gatagaatta
     3481 acttgaggtg atgaaaatgg caaccgataa aaatagaata atgattagct tggatgataa
     3541 aaatctagag aaacttgaaa atttagtaga agatgctaga gatagaaggg gaatgcgact
     3601 aacaaagtcc caggttattg aattactcct aaataccgtt gattatttcg atgatattat
     3661 gggggctatt tactcaaaaa aataagagca aaattgctat tattttttac aaattggtgt
     3721 aacactagtg atataggagt gatgaaatgg ttgtttatat tagacaaagt aaattaccaa
     3781 gtgaggtttc aattaataaa tacaatgctc aagtaggtgc ctacttacaa ggagaagaag
     3841 ttattttata tcaatctttt tctgaaataa aagagttaac aagtgaagat atagttgtag
     3901 attatataat ggagactaga gcattactaa aaatgatggg cttaaacgtt ccggttcatg
     3961 actatcctat tgagcttaaa gagttttatg gtcgaaagat ttatgctggt attttaggag
     4021 agattgtgaa tatacctgat aattggggaa aatttattaa gcctaaagct ggttcaaaag
     4081 tctttactgg aagagttgtt aatgaaaccc atgatttaat aggtattggt ctacctttcg
     4141 actatcctat atggattagt gaggttgtag aattcatagc tgaatggcgt tgttttgtgt
     4201 tagatggtcg cgtattagat gttcgaccct atacaggtga ttatcatgca caatttgatg
     4261 caagtgtaat tgatgaagcg atatcatgtt ggaaagatgc gccaatagct tatggactag
     4321 atatcggtgt tactcgcgat ggcagaacac ttgttgttga agtaaatgat ggttatgcat
     4381 tgggaaatta tggcctatct cctttaaaat caatcaattt tcatagagct aggtggaaag
     4441 aaatggtaaa accctatttt gaaaaaatga aatttttaaa atccaacagg atgttatttt
     4501 ctaaaataaa tatggtagat aaccaatata aaaagcatca aaatgaacaa ggaggaatct
     4561 gatgcttgga gcaattattg gagatattgt cggttctgtt tacgaatgga acaatatcaa
     4621 aacaaaggac tttcctttat ttcggaagga ctgctttttt acagatgaca cggttatgac
     4681 ctgtgctgtt gcagaagcaa ttatgaatgg tggacaaaaa gacgatttca ttgacgcgat
     4741 gaagaaatat ggcagaatgt atccgaatgc tgattacggt gctcggttta atgcatggct
     4801 aaacagcgat aaccgtgagc cttataatag ctttgggaat ggatcagcta tgcgtatttc
     4861 tccatgtgct tggatcatgg actgtggttt ttatgcgaaa actggtatgt ggccatcatc
     4921 tagaggactt acgagtcttt ctgcagaggt aactcataat catccagaag gtgtcaaagg
     4981 cgctatggct acagctgatg ctatctttct atgtcgtttt tactttggtg gttattgtag
     5041 agagtacgag caatcaatta acgacaatcc tacagagtgt aaaagacgaa ttaaggatta
     5101 tatagaaaaa gaatacgatt acaatctatc tcaaacttta gatgaaatcc gtcctaacta
     5161 tcgttttaac gaaacatgtc aggaaactgt ccctcaagcc attatcgcct ttcttgaaag
     5221 tagagacttc gaagatgcga taagaaatgc catctcactt ggtggcgaca gtgatactct
     5281 cgcagcaatc acttgtagca tagcagaggc agcttacggt attcctgatt ggatcaagga
     5341 taaggcctat tcttacttgg atgaaccctt aaaggatgta gttaggcgat gggaaaatag
     5401 aataaaagcg tattaatctc cagtacgtca gatttctctt ttctgtattt tcattgtata
     5461 ataggattac atttacttgc atgcgacgaa atgtaaacat ttctgtttaa aattaaggat
     5521 aaaatcaatg aaaaaagcaa tggtaattat caaccctact tctggtggcg agaaggcttt
     5581 ggattacaaa gaaaagctgg agaataaagc aaaagaatac tttgaatatg ttgaaaccaa
     5641 aattaccgaa aaagtgctgg atgcaacaca ttttgctgaa gaagcttctc gtgagcagta
     5701 tgatgcagtg gttgtgtttg gtggagatgg aactgtcaat gaagtcattt caggtattga
     5761 tgagagagac tacattccta agttagggat tatcccaggc ggtacgggta acctcattac
     5821 aaaacttttg gaaatcaatc aagacatcga tggcgcaatt gacgaactag attttgattt
     5881 aaccaataag attgatatcg gtaaagcaaa tgacaactat tttggttata tctttagtat
     5941 cggttctctg cctgaggcga ttcacaatgt tgaaatagag gacaaaacaa aattcggtat
     6001 tttaacctat gctgtaaata ccatgaagtc tgtcatgaca gatcaggtct ttaacattaa
     6061 ggttgagaca gaaaatggaa attatgttgg tgaagctagc catgttttgg tccttttgac
     6121 aaattacttc gctgataaga aaatctttga agaaaacaag gacggctatg ccaacatttt
     6181 gattctgaaa gatgcctcta tattctccaa attatccgtc attcctgatt tattaaaagg
     6241 ggatgttgtc gcaaatgata atatcgagta tatcaaagcg cgtaatatta aaatctcttc
     6301 agatagtgaa ttggagtcag atgttgacgg agataaatca gataacctac ctgtagaaat
     6361 caaagtccta gctcagcgag tagaagtatt ttcaaaaccg aaagaggatt agtatataga
     6421 gaaagccttt tttaaggctt tttgtatact ttaaaagata gttcctttaa caacggacat
     6481 tccttgcaaa tagtttacaa aaatagtata ctggatttat tgagtttgaa aacgtttgcg
     6541 taaaatttga atgaatactt taggagacaa attgatggaa ttgagtgcta tttaccatgg
     6601 gcctgagtcg gagtatgcct atctttataa ggataagaaa ctccatattc gaattcgaac
     6661 taagaaaggg gacattgaaa gcatcaactt gcactatggg gaccctttta tctttatgga
     6721 ggagttttat caggatacaa aagaaatggt caagataact tctggtacct tatttgacca
     6781 ttggcaggtt gaagtgtcag ttgactttgc acgtatccag tatctctttg agctcagaga
     6841 tacagaaggt caaaatattt tgtatggcga taaagggtgt gtggaaaatt ctctagaaaa
     6901 tcttcatgca attgggaatg gatttaagtt gccttatctt catgagattg atgcctgcaa
     6961 ggttcctgac tgggtttcaa atacggtatg gtatcagata tttcctgaaa gatttgccaa
     7021 tggcaatgct ctattaaacc cagaagggac tttagactgg gattcatctg tcacacctaa
     7081 gagcgatgat ttctttggtg gtgatttaca ggggattatt gatcatatgg attacttgca
     7141 agacttgggt attactggac tatatctttg tcccatcttt gaatctacaa gcaatcacaa
     7201 gtacaatacg acagattact ttgaaattga ccgtcatttt ggagacaagg agacctttcg
     7261 ggaactggtg gatcaagcgc atcatcgtgg catgaaagtc atgctggatg cggtatttaa
     7321 tcatattgct tcgcaatctc ttcaatggaa aaatgtcgtc aaaaatggtg aacagtctgc
     7381 ttataaggat tggttccata ttcaacaatt cccagtgaca actgaaaagc tagttaataa
     7441 gagagactta ccctatcatg tttttggttt cgaggactat atgcctaagc taaatacagc
     7501 caatccagag gtcaagaatt atcttttaaa ggttgcgact tattggattg aagagtttaa
     7561 tatcgatgct tggcgtttgg atgtggctaa tgagattgac catcagttct ggaaggattt
     7621 tcgtaaggca gttttagcta aaaatcctga tctttatatc ctaggagaag tctggcatac
     7681 atctcagcct tggctaaatg gagatgagtt ccatgccgtc atgaattatc ctttatctga
     7741 tagtatcaag gactatttct tacgaggaat taagaagaca gaccagttca tcgatgaaat
     7801 caatggagag tctatgtatt acaagcagca gatttcagag gtcatgttta atctcttgga
     7861 ttcacatgat acagagcgaa tcctgtggac ggccaatgaa gatgttcaac tggttaaatc
     7921 agccttagcc tttctctttt tacaaaaagg aacaccgtgc atttattacg gaaccgagct
     7981 agccttgact ggaggaccag atccagattg tcgtcgttgt atgccttggg aacgtgtatc
     8041 aagtgacaat gatatgctga actttatgaa gaggctgatt aagattcgga aatacgcgtc
     8101 agtaatcatt tcgcatggca agtatagcct tcaagaaatc aactctgatc tagtagctct
     8161 ggaatggaaa tacgaaggac ggatcctcaa agcaatattc aaccaatcaa cagaagatta
     8221 tcttttagag aaagaagcag tagcactagc aagcaattgc caagaattgg ataatcagct
     8281 tgtcatctct ccagatggat ttatgatttt ctaaaaacta gttgatgaag attatggtac
     8341 atttcatacc ttatatagta taataaggct agttactaaa cttgtaaagg agaacttaaa
     8401 tgaattgtag aggacatgaa acaagacaaa gaattgttag agattttgaa gttcagccta
     8461 aagtacatat taagctgtta gcaaatcaac aaaaacatag tgatgcagta gcaactattg
     8521 aagatgaata ttatgtattt atcgctgaga gtaaaattga tggcaagaag gaagttattc
     8581 agtgttgcat gggtgcggca agggattttt tagaactaat taatcacaaa gggctacctc
     8641 tttttaatcc gcttgtaggt gattctcatg taaataatag acaagaatat gacaatacag
     8701 ggagtggaaa tttataacct gaaaagtgga atgaaactgc aaagcagctt tataatgcta
     8761 taatgtggtt gattatttta tggaatgcta agccggatac acctttattt aattttaaag
     8821 acgaagtaat taagtataaa acatatgagc cttttgaaag cagtataaaa agagtaaata
     8881 ctactataaa gaatggtagt aaagggaaaa ctctgactga gatgattaat ggctacagag
     8941 cggataacga tattagagat gaaatttgta actttaatat tctgaaaaat aaaattcgtg
     9001 atatgaaaga ccaacaagga aatacaatgg aatcttactt ttagttattg ttgaattttg
     9061 ggtattctat aaaatatcct aattgagatt taaatagtag actatacaat atagttaaaa
     9121 tatcagtaaa aacaacactt tattgaggta ttggatacgc tttgctaata gcctaataat
     9181 cacatgtgga gtgttgctac aacgaaaaag gcgataatcc ttgatttcaa actattttat
     9241 aagcattttg tctttgtaga taaaggcaat tttgacaata aaaatcctaa aaggtgaatc
     9301 gttatagatg tatttgtaga tatcgtttgc gcatcgaaaa aattaataca agaataaata
     9361 tttatggctc tttaggtgac ttttatagaa gtaaagttta ggatagaaaa acaagaaata
     9421 atgcaccatt tttggtgcat tatgcttttt tatgctataa ttgaattata aaaataaagg
     9481 agtttgccat gattggaaag aacataaaat ccttacgtaa aacacatgac ttaacacaac
     9541 acgaatttgc acggattgta ggtatttcac gaaatagtct gagtcgttat gaaaatggaa
     9601 cgagttcagt ctctaccgaa ttaatagaca tcatttgtca gaagtttaat gtatcttatg
     9661 tcgatatcgt aggagaagat aaaatgctca atcctgttga agattatgaa ttgactttaa
     9721 aaattgaaat tgtgaaagaa agaggtgcta atctattatc tcgactctat cgctatcaag
     9781 atagtcaggg aattagcatt gatgatgaat ctaatccttg gattttaatg agtgatgatc
     9841 tttctgattt gattcatacg aatatctatt tagtagaaac ttttgatgaa atagagagat
     9901 atagtggcta tttggatgga attgaacgta tgttagagat atctgaaaag cggatggtag
     9961 cttaatggaa atccaagatt atactgatag tgaattcaaa catgctttag caaggaatct
    10021 tcgttcactg acaagaggaa aaaagtccag taagcaacct atagcgattt tgcttggagg
    10081 tcaaagtggt gccggtaaga ctacaattca tcgtattaaa cagaaagaat ttcaaggaaa
    10141 tattgttatc atagatggtg atagttttcg ttctcagcat ccacactatt tagaactgca
    10201 gcaagaatat ggcaaagaca gtgtagaata taccaaagat tttgcaggaa aaatggtaga
    10261 gtctttagta acaaaattga gtagtttggg atacaatctt ttgatcgagg gaactttacg
    10321 aacaattgat gttccaaaga aaacggcaca actcttgaaa aataagggat atgaagtaca
    10381 attggcctta attgcgacaa agcctgaatt gtcgtatcta agtactctta tccgttatga
    10441 agaactgtac attatcaatc caaatcaagc acgcgcaact ccaaaagaac atcatgattt
    10501 cattgtaaat catctagttg ataacacacg aaaattggaa gaactagcta tctttgaaag
    10561 aattcaaatt taccaacgag atagaagttg tgtatatgat tcaaaagaaa atacaacttc
    10621 agcagcagat gttcttcaag agttattctt tggggagtgg agtcaggtag agaaggagat
    10681 gttgcaggtg ggggaaaaga gacttaatga attacttgaa aaataaacaa ttgatatttt
    10741 taggagaata gaaatgagag ggtttaataa caagataaag tctgtttatc aagaactaac
    10801 aaattccaaa gagaaattcg gtagctttca caagacttta attcatttgc atacacctgt
    10861 ttcttatgat tacaagctat tttctaattg gactgcaacg aaatatagaa aaatt
//
LOCUS       DAVLBE010000060        10864 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.060, whole genome shotgun sequence.
ACCESSION   DAVLBE010000060 DAVLBE010000000
VERSION     DAVLBE010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10864)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10864)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10864
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.060"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            116..280
                     /locus_tag="VXB91_001716"
     CDS             116..280
                     /locus_tag="VXB91_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEV0471130.1"
                     /translation="MGIIANVFAGLVGAYAGQSLLGSWGPSIAGMALLPSIVGAAIVI
                     TVVSFFTGRK"
     gene            364..930
                     /gene="amaP"
                     /locus_tag="VXB91_001717"
     CDS             364..930
                     /gene="amaP"
                     /locus_tag="VXB91_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HEV0471131.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            942..1112
                     /locus_tag="VXB91_001718"
     CDS             942..1112
                     /locus_tag="VXB91_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HEV0471132.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            1151..1759
                     /locus_tag="VXB91_001719"
     CDS             1151..1759
                     /locus_tag="VXB91_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEV0471133.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            1790..1993
                     /locus_tag="VXB91_001720"
     CDS             1790..1993
                     /locus_tag="VXB91_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEV0471134.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLSGDDK"
     gene            complement(2103..2381)
                     /locus_tag="VXB91_001721"
                     /pseudo
     CDS             complement(2103..2381)
                     /locus_tag="VXB91_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007895264.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(3145..3915)
                     /locus_tag="VXB91_001722"
     CDS             complement(3145..3915)
                     /locus_tag="VXB91_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HEV0471135.1"
                     /translation="MVEIIYFLIIIIASGLGSISGMGGGIIIKPLMDSFGYHSVSDIA
                     FYSSFSVFIMAIISTTKRFSQSKEIKWRLIFTVSFSSVLGGFLGHLIFQVLLSQLSVR
                     LVSIVQMILLFVMLLVSFVLTDFKKTYQFDKIGFYMICGLLLGLISSFLGIGGGPLNV
                     SLLMVFFSISIKEATMYSLAIIFFSQLSHLATIVVVTGLNQYHLAPVPVIFLASICGG
                     VLGTVVSKVLPENWVRYCFKGMLFFVMGMTLYNLFHIL"
     gene            complement(3930..4778)
                     /locus_tag="VXB91_001723"
     CDS             complement(3930..4778)
                     /locus_tag="VXB91_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formylglycine-generating enzyme family protein"
                     /protein_id="HEV0471136.1"
                     /translation="MKMKKIKGGTFMMGTNSEEGFLDDFEDPQVAVSVKDFSIADTPV
                     TNQEFAQFVKETGYKTLAERQEWSFVFILFVPEAEREGYPHPAGAPWWLQVPNACWKH
                     PYGENSNLVGLEDHPVVHVALEDALAFCNWSGMSLPTEAQWEYAARGGRQSEYPWGDT
                     LLEGGYYHANTWQGRFPYENTGLDGFIGTAPVYEFLPNDFGLYQMIGNVWEWCRNPRY
                     TLLASFNEDDYELPKYGIQDEEYAIRGGSFLCHCSYCNRYRVAARNGCISTSTSSHLG
                     FRCLKE"
     gene            complement(4775..6250)
                     /locus_tag="VXB91_001724"
     CDS             complement(4775..6250)
                     /locus_tag="VXB91_001724"
                     /EC_number="3.1.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arylsulfatase"
                     /protein_id="HEV0471137.1"
                     /translation="MVQTKQPNIILIVVDQMRADALSLNSKDKLVSTPTLDMMASVGY
                     NFENAYSPVPSCVPARAALLTGLDQDKSGRVGYQDEVPWNFTNTLPKVFKDMGYQTEC
                     IGKMHVFPSRQRLGFDHVLLHDGYLHVDRKYDKAYGSQFDYASDYLAFLKGKVGYDVD
                     LIDDGMDCNSWEARPWDKDEKLHPTNWVVSESISFLQRRDPTVPFFLKMSFEKPHAPL
                     NPPKYYFDMYMERLPQFLDLHIGNWEVLEKQIPSIYALRGKLKEDDQRRMVAAYFGLI
                     THIDHQISRFLTALKEFRHDKDTIIWFVSDHGDQLGEHYLFRKGYPYQGSIHIPSFIY
                     DPAGLIAGNRGTIKQLVKIQDIFPSLVDLAGGTTTDELDGRSVKNLLFGQYEGWRTEF
                     HGEHALGKDSSQYILTDQWKFIWFPVLNHYQLFDMKKDPHEMNDLYPSEKYQPIVRQM
                     KKKLVNFLRYREEGFVVDEELVPVELSKITPTLTKTGDSQS"
     gene            complement(6573..7928)
                     /locus_tag="VXB91_001725"
     CDS             complement(6573..7928)
                     /locus_tag="VXB91_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV0471138.1"
                     /translation="MNTMLDKMQEKLSPIAMKVGNQKFLVALRDSFVGTMPVIMTGSI
                     ALLLNAFLVDLPQQFHLESITKTFQWLVDINNLVFKGSIPIVSLLFIYCLGVNIAKIY
                     KVDTVSAGLVSLASFVISIGSTVTKSFPLANVGDVKLNQILQGIDNLAFDGKNLMVTI
                     GNVIPGNHINARGYFTAMMIGFLASIIFCKVMKKNWVIKLPDSVPPAIAKPFTSIIPG
                     FMAMYIVAILTYVFHLLSNDLLIDWVYKVLQTPLLGLSQSFFAVILMIFLNKLFWFFG
                     LHGGNVLAPIMEGLFGVAMLANLDAFQKGEPIPYIWTSGSFGAFVWFGGLGLVLAILI
                     FSRNSHYRKVAKLGLAPVLFNIGEPVNYGLPVVLNPLLFIPFVLSPVFMATVAYWATS
                     WGLVSPVTQNVTWVMPPILYGFFSTAFDWHAIILSVVCLIISVLTYFPFVKMADKTEL
                     S"
     gene            complement(7938..8255)
                     /locus_tag="VXB91_001726"
     CDS             complement(7938..8255)
                     /locus_tag="VXB91_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV0471139.1"
                     /translation="MNESNLESAMGLIMYGGEAKSNAMEAIQAAKKGDFSKANRRLAD
                     ANAALLQAHKAQTEMLTREAQGEETSISLLMVHAQDHLMTSLTFVDLAKEVVEVYERF
                     EKN"
     gene            complement(8272..8589)
                     /locus_tag="VXB91_001727"
     CDS             complement(8272..8589)
                     /locus_tag="VXB91_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0471140.1"
                     /translation="MAKVTIMLACAAGMSTSLLVTKMQKAAEDKGLDAEIFAVPAPEA
                     EEIVATKEVNVLLLGPQVRYLLGDFQEKLKDRQIPVAVIPMTDYGMMNGSKVLDLAES
                     LLD"
     gene            complement(8604..9500)
                     /locus_tag="VXB91_001728"
     CDS             complement(8604..9500)
                     /locus_tag="VXB91_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HEV0471141.1"
                     /translation="MKRLISANPSEILQMNAEELKQSILASEGRVVLSENVVTRETFV
                     GDITNSEIARAFGADMILLNCVDVFEPKIYALDSSGDDVIHRLHQLVACPIGVNLEPI
                     DPSAKMLEETQEIVAGRVASVETLNRIEELGFDFVCLTGNPGTGVSNREIIKAVQTAK
                     ENFSGLIIAGKMHGAGVNEPVAELSVAEQLLEAGADVILVPAVGTVPAFHDQELREVV
                     DLVHSKGGLVLSAIGTSQETSDTDTIKEIALRNKICGVDIQHIGDAGYGGLATVDNIY
                     ALSKAIRGVRHTVSRLARSVNR"
     gene            complement(9503..10765)
                     /locus_tag="VXB91_001729"
     CDS             complement(9503..10765)
                     /locus_tag="VXB91_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV0471142.1"
                     /translation="MEKLLQEKLLPVAARLGNNKALVSIRDGITLTIPLLLIGSLLMV
                     IASFPIPGWEKYLGDIGVADYLWKGVDSSFGLLGLVASFGIAYFMARQYKVDGIPAGI
                     VSLSSFITVTPFIRGEAGAGMPTAFMASKGLFVAMILGLINGYIYQWFINHNIQIKMP
                     DGVPPAVSKSFSAIIPGAVTIVGWLIVYATLDKLSLPNLHEIAQVALGGPLGLLGNNV
                     IGLLILIFLNSSFWFVGLHGGNVVNAVMKPLWLANLDANKVAYQTGETLPNIFTSVFM
                     DNFVFIGGGGATIGLVLALGYLAHKKKASKQLKTLAPITVIPGLFNINEPAMFGVPIV
                     LNILLLVPFILAPMFNLLVAWGAMASGLVPLTYTDPGWTMPPVISGLLATGSISGSLL
                     QIVLIVLDVLLYLPFVIAIEKRFKLLED"
BASE COUNT         3724 a         2185 c         1683 g         3272 t
ORIGIN      
        1 agaaattgat tttttgatat taaaataaaa aaggagggta ggcagtgttg tgatcaatta
       61 ttgctggagg tcttattggt ctcttggcag gtaaaatcac taaaaaagta gttctatggg
      121 aatcatcgca aatgtattcg ctggtttagt cggggcatat gcaggacaat ctcttttagg
      181 tagttggggt ccatcaatcg ctggaatggc tttgctccca tctattgtag gtgcagcgat
      241 tgtgattact gtagtgtcat tctttacagg tagaaagtaa acttttcgcc agtaaagtta
      301 gcaaactatt tttaaatcaa tgacgggaaa aatagtttaa atgttaaatc gaaaggattg
      361 tatatgtcaa aagcaaagaa aatatgtttc attattttct gtattttaat cttgacaatt
      421 ttccttcctg ttttgataga ttatcatcaa gttagtgatc taggtattca tctacttagc
      481 tggagacaga actccgtagt tgaattctat cttgctagat atgtcttttg ggggacagtg
      541 gttctatcaa ctttagtttt attatccatt ttagttgtga tgttttatcc taaacgttac
      601 ttggaaatcc aacttgaaac taaaaacgat acattaaaat taaagaattc ggcaatcgaa
      661 ggttttgtta gaagtttggt gagtgatcat agattgatca agaacccaac tgttcatgta
      721 aatttacgaa aaaataaatg tttcgttcat gtagaaggta aaattcttcc ttcagacaac
      781 atcgctgaca gatgccaaat aattcaaaat gaaataacta atggattgaa gcagtttttt
      841 ggtattgagc gtcaagtaaa acttgaagtt gcagtaaaaa attaccaacc aaaacctcaa
      901 aacaaaaaga ctgttagtcg tgtgaagtaa ggaagtaaaa aatggaatgg cttaaacaat
      961 atcgatatcc aattatcgct ggtctcatag gcgtatttct ggcttgtttg attgtctcct
     1021 ttggcttctt caaaacaata tttgtattga ttttaggagc actgggagtt gcagctggat
     1081 tatatatcga aaaaaactat atagataaat aaaaaaataa aaattactaa tttaattaaa
     1141 ggagtttcat atgtcaaacg aaaaaaacac aaacactaac gtagaaaaga aagatgctac
     1201 tgttgtagct cacgaaatca aaggggaact tacttacgaa gataaagtta tccaaaaaat
     1261 cattggtctt tcactagaaa acgtttcagg tcttttggga atcgatggtg gtttcttctc
     1321 aaatcttaaa gaaaaaatcg ttaacagcga tgacgtaaca agtggtgtta acgtagaagt
     1381 tggtaaaaca caagttgcag ttgacttaaa cgttattgtt gagtaccaaa aaaatgttcc
     1441 agctttatat tcagaaatca gagaaatcgt atcttcagaa gttgctaaaa tgactgactt
     1501 ggaaattgtt gaaatcaacg taaacgttgt cgacatcaaa actaaagaac agcatgaagc
     1561 agactcagta agccttcaag atcgcgtatc tgacgttgct gaatcaacag gagaattcac
     1621 ttcagaacaa ttcgaaaaag ctaaatctgg tcttggatct ggtttctcaa ctgttcaaga
     1681 aaaagttagc gaaggtgtag aagctgttaa aggtgcagca aatggtgtag tatctcacga
     1741 aaacactcgt gtaaactaag ataaaataaa tataacagga gaaattatca tgtcagtaga
     1801 agaaaaatta aatcaagcta aaggttctat taaagaaggt gttgggaaag ccatcggtga
     1861 tgaaaaaatg gaaaaagaag gagcagctga aaaagttgtt tctaaagtaa aagaagtcgc
     1921 cgaagatgcc aaagacgctg tagaaggtgc tgtagaaggt gttaaaaaca tgttgagtgg
     1981 cgacgataaa taaggttaaa agttacttta tctttttagt aacattagtc aaaagagtct
     2041 gagtcaagat gattctcaga aaacaaaaag ctagagattc ccaattgcgg aactctagct
     2101 ttttaatttt gcctctttct cttattatat ttcagcaggt tgttggccat gagtatgaat
     2161 cccatgtcaa ttctcacttg acgcttacct ctcagatgac atctcttata acccaaacaa
     2221 acctttatct gcccaaagac agatttcata tcaatcttac gtttagcgaa aatttgtcta
     2281 cccttggaag ataaaagtgc ctgatattct ttagttttta aacactggta acgttcattc
     2341 atatacagtc ccttttgagg ggctgattca ggttcataat cgcagtcaac attgatttca
     2401 aggctgtttg ctttctatct cccctttttc atgatatatt ttcgtacagg tgcttcaata
     2461 gtttctatag taaaatgaac caaaaatagt acacgttgcg gtataatgtt cttgtggcat
     2521 attcattaga ttttcgtaaa aagttctctc ctatttgtga gcgaacaggt atagtcaatt
     2581 gattgtcagt ttgaagacca agagtcgtaa ggcaaaggat atggcagaat ccatccaagg
     2641 gtggctggca caatttctag tgaacctctt taaatctatt acgtttgact gtggaaaaga
     2701 gttttcaaaa tggaaagata tttccaatca tcacgatagt gagagctttt ttgcgaatct
     2761 aggatgtcca agatagcggt gtctcaacga acattcaaat agacttttaa ggtgtcatga
     2821 cttgccaaag cagacagatt tcaacgaagt cagtcaagaa ttttaggctg ggcaagaact
     2881 caatttcagg agaaaatgaa ataaatattc ccacaataaa acgcatagta tcaaagtttt
     2941 tccaacacct gatattatgc attttttaat tttaaagact ttttcccagc ctcaagaaat
     3001 cacatcccac ctaaatcctt tggataccaa atacctcatc aggttatttt ctgagttggt
     3061 aagactgtct agcttaattt gacaaatgga gggcgttaaa tccagttttt acaggaagtc
     3121 tatttaaata ttttcacact gaccttacaa aatatgaaat aaattatata aagtcattcc
     3181 catgacaaag aataacatcc ctttaaaaca gtatcttacc caattttcag gtaagacttt
     3241 tgatacaacc gtccccaata cccctccgca tatagaagca agaaaaataa ctggaacagg
     3301 tgctaaatga tactgattta aacctgtaac cacaacaatt gtagccaaat gagacagctg
     3361 ggaaaagaaa ataattgcaa gagaatacat cgttgcttct tttatcgaaa tagaaaaaaa
     3421 caccatcaat aaagatacat tgagcggacc tccaccaatc cctaaaaaac tagaaatcaa
     3481 gcccaataga agaccacaaa tcatatagaa tcctatctta tcaaattgat aagttttttt
     3541 aaaatctgtt aaaacaaatg atacaagtag catcacaaat agtaaaatca tttgaacaat
     3601 ggatactagc cgtactgata attgagataa caaaacttga aaaataagat gacctagaaa
     3661 tcctcctaaa acagaagaaa aggataccgt aaaaatcaat ctccatttta tctctttact
     3721 ttgtgaaaat cttttggttg ttgaaataat cgccattata aaaacagaga aactagaata
     3781 aaaagcaata tcactgaccg aatggtatcc aaaactatcc ataagtggct taattataat
     3841 tccaccaccc atgcctgata tagaacccaa tccactagct attataatga ttagaaaata
     3901 aataatctca accacttttt aagtccatcc tattctttca aacatctaaa acctagatgg
     3961 ctactagtgg aagtagaaat acatccattt ctagcagcta ctcggtatcg attacaataa
     4021 gaacaatgac ataaaaagga acctcctctg atagcatact cctcatcttg tatcccatat
     4081 tttggcaact catagtcatc ttcattaaaa ctagctaata aggtatatct cggattgcga
     4141 caccattccc aaacattccc aatcatttga tatagaccaa aatcattagg taaaaattca
     4201 tagacaggag ccgttcctat aaatccatct aagccagtat tttcataagg aaatcttcct
     4261 tgccaagtat tggcatgata atatccacct tctaaaagag tatctcccca aggatattca
     4321 gattgtcttc ctcctctagc agcgtattcc cactgtgctt cagtcggtaa agacattccg
     4381 ctccaattac agaaagccaa tgcatcttct aaagcaacat gaactactgg atggtcttct
     4441 aaacccacta gattactgtt ctcaccgtag ggatgtttcc agcaagcgtt cggaacttgt
     4501 aaccaccacg gagccccggc aggatgagga tatccctccc tttctgcctc cggaacgaac
     4561 aatataaaaa caaaagacca ctcttgtcgc tcagctagtg ttttatagcc tgtttctttc
     4621 acaaattgag caaattcttg attcgtaact ggagtatccg caatggaaaa atcctttaca
     4681 ctaacagcga cttgaggatc ttcaaaatca tctaaaaagc cctcttcaga atttgttccc
     4741 atcataaatg tcccaccctt gatttttttc attttcatga ttgactatcc cccgttttcg
     4801 ttagagttgg cgttatttta gaaagttcaa caggaactaa ctcttcatcc acaacaaaac
     4861 cttcttctct atatctaaga aagtttacta attttttctt catctgacga acaataggtt
     4921 ggtatttttc acttggatac aaatcattca tttcatgcgg atcttttttc atatcaaata
     4981 actgataatg atttaaaaca ggaaaccaga taaatttcca ctggtctgtc aaaatatatt
     5041 gactagaatc ttttcctaaa gcatgttcac catgaaattc tgttcgccac ccctcgtact
     5101 gtccaaataa taaattctta acactccgtc catctagttc atctgtagta gttcctcctg
     5161 ccaaatccac gagtgaagga aaaatatctt gaattttcac taattgcttg attgttcccc
     5221 tattaccagc tatcaatcca gccggatcgt aaataaacga aggaatgtgg atacttccct
     5281 gataaggata tccctttcta aacagataat gttcaccaag ctgatctcca tgatccgaaa
     5341 caaaccagat aatcgtatct ttatcatgac gaaattcttt tagggcagtc aaaaagcgac
     5401 taatttgatg gtctatatga gtaatcaatc caaaataagc agcaaccatt cttctttgat
     5461 catcttcctt taatttccct cttaaagcat aaatagacgg aatttgcttt tctaatactt
     5521 cccaattccc gatatgcaaa tcgagaaatt gaggcaagcg ttccatatac atatcaaaat
     5581 agtattttgg gggatttaat ggagcatgtg gtttttcaaa agacattttg agaaaaaaag
     5641 gaaccgttgg atctcttctt tgtaaaaatg aaatggactc actcacaacc cagtttgttg
     5701 gatgtaactt ttcatcttta tcccaaggtc tagcttccca agaattacaa tccattccgt
     5761 catcaatcaa atcaacatca taaccaactt taccctttaa aaaggctaga tagtcactag
     5821 cataatcaaa ttgacttcca taagccttat catactttct atcaacatgt agatacccat
     5881 cgtgaagtaa gacatgatca aacccaagtc tctgtctgga aggaaaaaca tgcatcttac
     5941 caatacactc tgtttgataa cccatatctt taaagacttt tggaagagta ttagtaaaat
     6001 tccaaggcac ctcatcttga taaccaacac gtccactttt atcttggtct aagccagtca
     6061 ataaagctgc cctagcagga acgcaagaag gaactggaga ataggcattt tcaaaattat
     6121 aacctacact agccatcata tctaatgttg gagtgctaac tagcttatcc ttactattca
     6181 aggataaggc gtctgctctc atttgatcta caacaatcaa aataatattt ggctgttttg
     6241 tctgaaccat aaaatctcct ttctaatatg gcaaaagagg cacaagaaga tatctacctt
     6301 tactgcaccc ctttctatat caatctctct atataaaaca ataacattct tgttatgttt
     6361 tatataaaaa tgaactaaaa tatgactaaa tcgattagga aattcaaatc attttctagt
     6421 actgttttag aagttacagt gtactattcc aacttcaata aactataaac ctttgtctat
     6481 taacaatttt agtggagata agaaatccta cacctaactc atcttacacg taatctattt
     6541 ctattttatc acaaaaaacg caagtaagac cattaactca attcagtttt atctgccatt
     6601 ttcacaaatg ggaaataagt caagacacta ataatcaaac aaacaactga taagatgatg
     6661 gcatgccaat caaatgctgt agagaagaaa ccatataaaa ttggaggcat tacccaagta
     6721 acattttgtg taacaggtga aacaagaccc cagcttgttg cccagtaagc taccgttgcc
     6781 atgaaaaccg ggctaagtac aaatggtata aatagcaaag gattcaagac aactggtaaa
     6841 ccataattga ccggctcacc aatattaaac agaactggtg ctagaccaag tttagcaact
     6901 tttcgataat gactgtttct tgaaaaaatt aaaatagcaa gtactaatcc taatcctcca
     6961 aaccagacaa acgccccaaa agacccactt gtccatatat aaggaatcgg ttcacctttt
     7021 tggaaagcat ccagattcgc taacatagca actccaaata gcccttccat gatgggagcc
     7081 aatacatttc ctccatggag accaaaaaac cagaataact tattcaaaaa gatcatcaga
     7141 ataactgcaa agaaactttg agacaaacct agtaatggcg tttgtaacac cttgtaaacc
     7201 caatcaatca ataagtcatt gctaagtaaa tggaaaacat aagtcaagat ggctactata
     7261 tacatcgcca taaatcctgg aatgatagaa gtgaacggct tagcaatcgc agggggaact
     7321 gaatctggta acttgattac ccagttcttt ttcattactt tacagaaaat aatagaggct
     7381 aaaaatccaa tcatcatggc tgtaaagtat cctctggcat taatatggtt tcctggaatc
     7441 acattcccaa tagttaccat cagattttta ccatcaaatg ctagattatc aattccttgt
     7501 aagatttgat ttaatttcac atctcctaca tttgccaaag ggaaactctt tgtaactgta
     7561 cttccaatcg aaatgacaaa cgaagcaagt gataccaaac cagcagaaac tgtatcaacc
     7621 ttgtaaatct tagcgatatt cactcccaag caatagatga acaataagga aacaattggt
     7681 atacttccct tgaataccaa attattgatg tcaacaagcc actgaaaggt tttcgtaata
     7741 ctttctaggt gaaattgttg tggtaaatcc actagaaaag catttaataa caaagcaatg
     7801 gaacctgtca taataacagg catagtcccc acaaatgaat cacgtaaagc aactaaaaac
     7861 ttctgattcc caactttcat tgcaattgga gaaagttttt cttgcatttt atccaacatt
     7921 gtattcatag caaattccta atttttttca aatcgttcgt atacttctac cacttctttc
     7981 gccaagtcaa caaaggtcag actcgtcatt aaatgatctt gcgcgtgtac catcaagagg
     8041 ctaattgaag tttcttcccc ctgtgcctct cttgtcaaca tttctgtttg agccttatgc
     8101 gcctgtaata aggcagcatt cgcatcagct aatcttcgat tggctttaga gaaatcccct
     8161 ttttttgctg cctgaatagc ctccatagca ttacttttgg cttccccacc atacataatt
     8221 agccccattg cagattctaa attactttca ttcatagcat tctcctcaat cttagtctaa
     8281 taaactttca gctaaatcta agactttaga accattcatc attccataat ctgtcatcgg
     8341 aataaccgcc acaggaatct gtctatcttt tagtttttct tgaaagtccc ctagtaaata
     8401 gcgaacttga gggcctaaaa gcaacacatt tacttccttt gttgctacaa tttcttctgc
     8461 ttcaggagct ggaactgcaa aaatttctgc atccaacccc ttatcttctg ctgccttttg
     8521 catctttgtc actagcagac ttgtactcat acctgctgca catgctaaca taattgttac
     8581 tttagccata gcttactcct ttatcaccta tttactgacc tagccaagcg agatactgta
     8641 tgtctcactc ctctaattgc cttgctcaat gcataaatat tatcgactgt tgccagtccc
     8701 ccatatcctg cgtcacctat atgttgaata tcaactccac aaattttatt tctaagtgca
     8761 atttccttga tagtatctgt atcagatgtt tcttggctag taccaatagc actcagtact
     8821 agcccaccct tactatgaac gagatcaacg acttcacgca actcttggtc atgaaaggct
     8881 ggaacggttc caactgctgg aacaagtatc acatccgcac ctgcttccaa caattgctct
     8941 gctacagaaa gctctgccac aggctcattc actcctgccc cgtgcatctt acctgcaata
     9001 atcaaaccag aaaagttttc cttagcagtt tgaacagcct taatgatttc tcgattgcta
     9061 actcctgttc caggatttcc agtcaaacag acaaagtcaa aacctaactc ctctattcga
     9121 ttcaatgttt caacactagc aacacgacct gcaacaattt cctgtgtttc ctctagcatc
     9181 tttgcagatg ggtcaatcgg ttccaaattt acaccaattg gacaagcaac aagctggtgt
     9241 aagcgatgaa taacatcatc acctgaacta tccaaagcat aaattttagg ctcaaaaaca
     9301 tcaacacaat tcaataaaat catatcagct ccaaaagctc tagcaatttc agaattagtt
     9361 atatccccaa caaatgtctc acgagtaact acattttcag atagaacaac tctaccttca
     9421 cttgctaaaa tactttgttt taattcttca gcattcatct gtaatatctc agatggattt
     9481 gcactaatta aacgtttcat tctcaatcct ccaataactt aaaccgtttt tcaatagcta
     9541 ttacaaatgg taaataaagt aagacatcca aaacaatcaa tacaatttgt aataatgaac
     9601 cagaaatact tcctgtagca agtaaaccac ttataacagg tggcatagtc caacctggat
     9661 ctgtataagt tagcggaacc aaacctgatg ccattgctcc ccacgctact agtaagttaa
     9721 acattggagc taagataaat ggaactagta acaaaatgtt caaaacaata ggaacgccaa
     9781 acattgctgg ttcatttata ttaaataatc caggtataac agttataggt gccaaagttt
     9841 ttagttgttt actagctttc ttcttatgtg ctaaatatcc taacgcaaga actaaaccta
     9901 tggttgcacc accgccacct atgaatacaa aattatccat aaatacgcta gtaaaaatat
     9961 ttggaagagt ttctccagtt tgataagcta ctttatttgc atctagatta gctaaccata
    10021 acggtttcat aactgcatta acaacatttc ctccgtgtaa tcctacaaac caaaaactac
    10081 tattaaggaa aattaagata agaagaccaa taacattatt tcctaaaagt ccaagtggac
    10141 ctcccaaagc tacttgagca atttcatgaa gattaggtaa acttaattta tctaaagttg
    10201 cataaacaat caaccaacca acaatagtca ctgcaccagg aataatggca ctaaagcttt
    10261 tagatactgc tggtggaaca ccatccggca tttttatctg tatattatga tttataaacc
    10321 attggtagat atagccatta atcaatccta aaatcatagc aacaaataaa ccttttgatg
    10381 ccatgaaagc ggtaggcatt cctgctccag cctctcctct aatgaaaggc gtaactgtaa
    10441 taaaagatga taatgacaca ataccagcag gaataccatc aactttgtat tgtctagcca
    10501 taaagtaagc gataccaaaa ctagctacaa gaccaagtaa tccaaaacta ctatcaacac
    10561 ccttccataa atagtcagca acaccaatat cacccagata tttttcccat cctggaatag
    10621 gaaaacttgc aataaccatt agtaatgaac ctatcaacaa taaaggtata gttagagtaa
    10681 taccgtctcg aatagaaacc aacgctttat tattacccaa tctagccgct actggaagta
    10741 acttttcttg taataatttt tccataacct tttcctctta aatatatttt attatcaaaa
    10801 gttatcaatt atctttattt tttgacgtca agttgttatt tgattatctt ttgttattta
    10861 tatt
//
LOCUS       DAVLBE010000061        10746 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.061, whole genome shotgun sequence.
ACCESSION   DAVLBE010000061 DAVLBE010000000
VERSION     DAVLBE010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10746)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10746)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10746
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.061"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(105..1529)
                     /locus_tag="VXB91_001730"
     CDS             complement(105..1529)
                     /locus_tag="VXB91_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HEV0471143.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAVERAAYLHKTAAILERDKEEIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEAASKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMFKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVADKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     GLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVAWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
     gene            complement(2074..4353)
                     /gene="pulA"
                     /locus_tag="VXB91_001731"
     CDS             complement(2074..4353)
                     /gene="pulA"
                     /locus_tag="VXB91_001731"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HEV0471144.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKAYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPDGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLAPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGSYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTGAFSY
                     SSYDEIYHHVFVHSAIEHSGYLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(4465..6423)
                     /gene="ligA"
                     /locus_tag="VXB91_001732"
     CDS             complement(4465..6423)
                     /gene="ligA"
                     /locus_tag="VXB91_001732"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HEV0471145.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVADSEYDRLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQVRQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KVSQLLLQYFHSIENLSQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSISKKTDLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(6516..7694)
                     /locus_tag="VXB91_001733"
     CDS             complement(6516..7694)
                     /locus_tag="VXB91_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV0471146.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSILVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQAIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LNMTLLLDSLTFFIAFVLVAFLPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FLLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGSIIGALLASKIKANI
                     YNLLILLALTGVGVFMMGLPLPTFLSFSGNLVCELFMTIFNIHFFTQVQTKVESEFLG
                     RVLSTIFTLAILFMPIAKGFMTVLPSVHLSSFLIIGSGVIILSCISFIYVRTHFEKLI
                     "
     gene            complement(7774..8637)
                     /locus_tag="VXB91_001734"
     CDS             complement(7774..8637)
                     /locus_tag="VXB91_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEV0471147.1"
                     /translation="MEHLGKVFREFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFHNHEHVSMMAQIIPLYYSNDIAGFQKLQREQLEK
                     SKSSTTSLYFELNWILLQGLICQRDATYDMKQDDLDKVADYLFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISRHKRLVLILALNCYQHCLEHSSFYNANYFE
                     AYTEKIIDKGIKLYERNVFHYLKGFALYQKGQCKEGCKQMQKAMHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            complement(8640..10541)
                     /locus_tag="VXB91_001735"
     CDS             complement(8640..10541)
                     /locus_tag="VXB91_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV0471148.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFDDLRRTDKQLR
                     QMELEMGEKSGEDLDKLMSDYDRLSENFRQAGGFTYEADIRAILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETISWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKYSLDRYVGNYSRFVELKEQKLATEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKAANMTFQSEKTSGNVVLTVENTAI
                     GYDGEVLSQPINLDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     HVLELSENGSTLYLGDYDYYVEKKATAEMSQTEEASTSNQAKEASPVNDYQAQKESQK
                     EVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSDQV"
BASE COUNT         3233 a         2366 c         1908 g         3239 t
ORIGIN      
        1 gtttcaatct attataatac caaaaagttc gtattttttc tataattatt attattttat
       61 agcaaaaaaa taaaaccagg aaaacaattt cctggtttta cacgttattt cacatcaaaa
      121 acaatggatt tgacatttgt catcgcttca atgctatatt taattccttg cactccagct
      181 ccagaacctt tgacaccaag gaatgggaaa ttatctggac cacgctgggt tttattatta
      241 atgtggactg tacctacttc aagtttttca gcaatttcaa aggctttttt gaaatcattt
      301 gtaaagactg atgattgaag gccgaattca gattcgttgg caaaggcaat agcttcctct
      361 acactagcca cacgaatgat tggtaaaaca ggaccaaatg gctcttccca tgccactttc
      421 atatcttttg taacttggtc aaaaagcact ggccagagaa gattgccctc acgtttgatt
      481 ggtgtaagag cctgagcttc tttttcttgt gcatcctcaa tcaagcccca aatgaagtcg
      541 gctgaagcat tgtcaataac aggtgtaata tcagcattgt caaatggatc accaactgtt
      601 aatttagaaa cttcttcctg aagcaaagta gctaatttat ctgctacact ttcgagaaca
      661 atgacacgtt taatggccgt gcaacgttgt cctgagtagc taaaggctcc cgcaacaatt
      721 tgcttggcag catgttccaa atctgcatct tctagtacaa gagctgcatc tttcccacca
      781 agttccaaca tgataggacg cataccagct aaacgaccaa tacgttctcc aataggagtt
      841 gaacctgtaa agttgatgaa gttgacttct ttgtgctcaa tgatataatc cccaatttct
      901 gaaccacgac ctgtaatggt gttgaaaaca cctgccggaa tccctgcttc ttcaaatgct
      961 ttagccaaca agagtccaga aatggaacct tgtgttggtg gcttaaacat gaccacattc
     1021 cctgcaatca aggcaggtgc aattttagaa gcagataaat taactggata attaaaggga
     1081 gcaatcgcta gcacgatacc aactggttca cgacggacaa cagccagttt gtttttactt
     1141 gctgcctcaa aaccaccacc ttccattgct tgtccagtga tacggagacc ttcctcagca
     1201 gcataacgaa tcaagtctgc tgtacgcact acttctccaa ttgctgcttt aatccctttt
     1261 gctacttctt tggcaaggat agtaccaatt tcttccttat cgcgttctaa aatagctgct
     1321 gttttatgta aataagccgc acgttcaact gctgataaag ctcgccatgc tggcagggct
     1381 gcacgcgcag cttgcatagc ctcatcagct tcagtctgag tcatggctgg aactgtaccc
     1441 aattcttctt gattgattgg tgaataaatc gtaatttctt gttcagatga tttccatttt
     1501 ccatttacta aattctgata tcttgtcaaa ttcttgtcct cctgaaaatg attaagatat
     1561 attttaccaa attttcagaa aatcacaacc ctttttgcaa aatttttgag attattttca
     1621 caaacttgat ttttcaaagt atactcaata aaaataaaaa aaatccacta cgtcaaggcg
     1681 aggctaatgt ggtttgaaga aattttcgaa gagcgtgaat gagtatcatc tatagtaaaa
     1741 taaaaaaact gaacaatttg gttggggaca gccaaaccaa tttctcacaa tgtttcagaa
     1801 acaagggtgt gctactccaa tttcagccta ctataactgt catagattgc tgaaacaaag
     1861 tctaggtaaa agtcttcata ataaaaagac ctcctatcaa gtgttcaaaa actttgatag
     1921 gaggtcttgt tttgtgaaaa tatttatcaa attttctata caagtgagct gttagccagg
     1981 ttctttctat tctttcaatt tcaatgaatg gattttttac taatactcat aactgggaat
     2041 ttgtctgtgt aaaaatagcg agatagatgg tatttataaa acactcaaga cagctagact
     2101 aatatcattt aaaacattat cttcttttga gcgactgttg gttaccaaca tagctaaatt
     2161 tcctgcattt tcaaattgat agggttctga tttagcattc acaaccacca agaggtgttc
     2221 tttgccgtga acttcataga taaggtagcc gctatgttca atcgcagaat gcacaaagac
     2281 atgatggtaa atttcatcat agctagagta agaaaaggca ccagtttttg tcttcaatcg
     2341 gatgacttga cggataaact caatactgtc ttgacgctca ttaatcaagt tccagttcac
     2401 ttggttcaca ctgtcaggag cattatagct attcatcgca cgctctctat catcatgggt
     2461 caactcacca ttttcaccag tcgcaaccag tttggtacga ccaaattctt gaccgatttc
     2521 cataaaggcc atcccctgca tgagcagatt catggctgtg gcagtttcga ccttgcgcat
     2581 gatttgctct gaactttggt ctggatgaag ggttgccaat aaatcgtgaa gattgtaatt
     2641 gtcatgggct tctacatagt taagcacctg atttggatgt gtatagcttc ctaattcacg
     2701 acttcctagg attgctttag ctagaattgg ctctgtcgca gcaccactga caaaacctga
     2761 cttgatagca ccataaactt ctcccccttt gacagcatcg cgctgattgt cattaaagaa
     2821 accaatattt ggcatctggt aggcattgtc cttcttggcc ttatcataag gggcaagacc
     2881 tgttcccata tcccatcctt ctccatagag gataatgttg gagtcgattt catccaagct
     2941 ttgacgaatc atctgcatgg tcttgacatc atgaatcccc atcaagtcaa aacggaagcc
     3001 gtcaatatta tattcctgca cccagtatag aagagaatca atcatatact tgcgaaacat
     3061 ttcgtgttca ctggctgttt catttccaac acccgttcca ttctggaagg taccatctgg
     3121 attcatacga taatagtaat cagggactgt tgtttggaat ggtgcatcaa caactgagaa
     3181 ggtatggtta tagactacat ccataatgac tccaataccc gcatcgtgat aagcttgaac
     3241 catcaccttc aaatcacgaa tgacctgagc tggatcatct ggattagttg aaaaactagt
     3301 ttctggcgcg ttatagtttt gtggatcata accccagttg taggttacat ttccatcctc
     3361 atcgtattct ttatgacggt ctgcaattgg ttgcaattga acataattgt agcccagctt
     3421 cttgatgtaa tcaaaagcag ttgactggcc gtattggtta actgttccag cctgagcagc
     3481 acccaagaaa gttcctcgaa gatgttcatc tacacccgat gtaggtgatt tagtcaaatc
     3541 acgaatatgc atttcacaga taactgcctt acatggattt tccaagcgcc aagtagcctc
     3601 cgaaccgtgc ttaacctcga agttttcaac ttgcttttct acatggctca gaatagctga
     3661 acgtttgcca tcagggctgg tcgcgattgt ataaggatca cgtgtcagtg tttggtgatg
     3721 agggaattgg acttgatact gataagcctt acctaccaaa tcttcctcaa catccaaact
     3781 ccagacaccg attgtattgt ccttatgatt ataagagtag ctattgcctc ttttcatctc
     3841 aaaagtcttc caaacgggtg catcattagc agctgattca taaacgacaa cttgcacttc
     3901 tgtcgctgta ggtgaccaga gggaaaaatg agcctgattg tcctctacac ggcaacccaa
     3961 ttctccttgg taaccccaat gatggtcaaa actagcactg ttaatggcct tatcaaaggc
     4021 aaaaggattt tgatttttat agaaaggact ggcaatagca ggattttcag agtaataaat
     4081 cctatcatcg ccttccaaaa tccagacctc tgttaatagg ggatagtgat taaaacggat
     4141 agaatattct ttactagttt gacctgtatg aaccacaaaa ttcaagcttt ctataacatg
     4201 tgaacttggg tgttcaaagc taaataaagc tccaaaataa tcttctttgt aggttagcaa
     4261 atcaattcgt tgatcctgac tttttacaaa ggagcaagtg tcatattctc cattcttacg
     4321 atggtaatga atgcgcatag ggtagttata cattttttat ttttcctttt tactttgttt
     4381 ctatttcact aataaatttt tgtcaatctc gtctcaatta acagacatag tcatattctc
     4441 taaactctgt ttttaaacga tccattacaa actttctagc catgcctcat ctctgacctg
     4501 gataccaagt tcttgtgctt tttgcagttt acttccagcg tctgcaccta ccacgacgag
     4561 gtcggtcttt ttagaaatac tacctgtcac tttggcaccc agactttcga gtttactttt
     4621 agcttctgag cgcttgagtc gttccaattt tcctgtcaat accacggtca aacctgacaa
     4681 ggccgcatcc gctactaccg tctgtccttt atagtccaga ttgaccccag tttctttcaa
     4741 ttctctgagc agaatttcag agccttctgt cgcaaaataa gtctgaagac ttttggcaat
     4801 cacgccacct agactttcaa tactagccac ttcctctgaa tctgcctgag acagattttc
     4861 aattgaatgg aaatattgaa gtaaaagctg actaaccttg cttccgacat gacgaattcc
     4921 caaaccaaat aagagcttct cggcagaatt ttcctttgat gcttggatag cctgatacag
     4981 tttagcagcg gacttttcct taaccccctc taaaaggagg aaatcctctt cttgcaaacg
     5041 ataaatatcc gccacatcct tgactaaatt agcagcaaaa agcttctcaa caatagatgg
     5101 accaaggcct gtaatattca tagcatcacg agaagcaaag tgaatcaagc cttccatgat
     5161 ttgagcaggg caacgcggat tgatacaacg tagggccact tcatcttcaa agtgcaacaa
     5221 gtcagagtta caacttggac agtttgtagg gatatctagt ttttcttcag aaacccgttt
     5281 ggactctacc acacgtaaaa cggcagggat gatgtcacca gccttatata caatgaccgt
     5341 atcgtctttt cggatatctt tttcagcaat ataatctaca ttgtgcaggg tcgcacggct
     5401 aacagtcgta ccggcaagtt gtactggtgt tagattagca gttggagtta caacaccggt
     5461 acggccaact gtccagtcaa ctgataagag ttgagcttct ttttcttcgg cagggaactt
     5521 gtaggctact gcccactttg gagccttaac tgtaaaacca agttcttctt gacttgctag
     5581 gtcgttgacc ttgattacca ctccatcaat atcgtaaggc agattttccc gttcctgtcc
     5641 tacttcttgg ataaaattcc agatttcatc tatgttttca gccaagattc gcttaggatt
     5701 gaccacaaaa cctagttgtt ctaggtactt caaacccttt tcttggctat cacgagttga
     5761 agggctggct tcttgataga gaaacgttgc aagattacgc ttggcaacta ctgctgtatc
     5821 caactgacgc agagttcctg ctgccgcatt acgaggatta gcaaattcag gctctccatt
     5881 ttcttggcgc acttggttaa cttggtcaaa ggaagcgcgt ggcatgtaac attccccacg
     5941 aactgtgata tctagttctt ctggcaaagt caaagggatg tccttaacac gcttgaggtt
     6001 ttctgtgata ttttcaccaa ttgaaccatc tccacgtgtt accccagcaa ccaaaatccc
     6061 cttttcataa gtcagcgaga tagataagcc atcgattttc agctcacaaa tataggtcgg
     6121 atgagccact tccttacgaa cacgcgcatc aaaagcatct agctcctcac gtgaaaaagc
     6181 atcctgcaaa ctataaagag gatactgatg actgtatttt tcaaaaccat ctaaaacctt
     6241 gccaccaaca cgatgagtcg gactgtctgc tagcacttgc tctggataag cagtttctaa
     6301 ctcgaccaac tcacggtaaa ggcggtcata ctcactgtct gcaaccgagg gattatcgct
     6361 ggtatagtac tcagtcgcat agcgattgag caaagcgact aactcattca ttcttttatt
     6421 cataagacca ttttaccata aaacaagccc tcctcacaaa cgagaagggc ggaaaaaaca
     6481 cttagtttga aattattttt gaaactcaag caaccttata tcaatttttc aaaatgagtt
     6541 cgaacataaa taaacgatat acaagacaag atgataacac cacttccaat tatcaggaaa
     6601 gaagagagat gtacacttgg caagactgtc ataaatcctt ttgcaatagg cataaataga
     6661 atagctaagg taaaaattgt actcagtact cttccaagaa attcgctctc aaccttggtt
     6721 tgtacttgag taaaaaagtg aatattaaaa atcgtcataa acaattcaca aactaaattt
     6781 ccagaaaagg aaagaaaagt tggaagtggt aatcccatca taaaaactcc gacacctgtc
     6841 aaagccagta aaatcaaaag attataaata ttagctttaa ttttactagc tagaagagcc
     6901 ccaatgatgg aaccaatagc ccccatagtt aaaatacttg cataggctcc ttctgacccg
     6961 taaagctgat tcgaaaaggg aagtagaaat tcaaaagctg caaaaaagaa attaacgctg
     7021 gaagctacca gcaaaaggaa gaaaatttct tgctgatgcc agatatagtg taacccatcc
     7081 ttgatatcta caaaaatatc tctcccagta aaagcctttt tctcttgaac ttttgcttcc
     7141 tcttttggaa ggaaagccac tagaacaaaa gcaatgaaaa aagtcagcga gtctagcagt
     7201 agcgtcatat tgagacttgc aaactgtaaa acaaggaagg aaagaacagg agagctaaca
     7261 cctacaacct gcaaaaccag ctctaagcga gaattataga tcacaatctc atctttctcc
     7321 accacttcag ttatgatagc tttattggct gtgcgagaaa aggcaaaagc aatagcctgc
     7381 acaatgttag caacaatcaa agcgccaatc atccagctat cattccttat gaaagaaata
     7441 gccagacaaa gaatcccaca aacaagatct gccgtcatta aaatcttacg acgagaaaaa
     7501 cggtctgaaa taactccgcc aaagggattg acgagaatag atgtgacgag ctcagaaatc
     7561 tgatacattc ctaaaactgt ctgtcctata gtccccatag aagccaacca gacactattt
     7621 ccataatcat agagcatatt tcccatttta ttgatagccc cacggctaat caactgcact
     7681 gcatagcgat tcatattaaa gctcctctca aattttgaaa ctattgtatc aaaaccgaaa
     7741 ggagcttttt attttttccc ttatttggga aaattaactt ttgacaaatt tttcgtagtg
     7801 ttcctgataa taggctactt gctctggaag acctaacaca tcaaaaatat gcatggcctt
     7861 ttgcatctgc ttacagcctt ctttacactg tcctttttga tataaggcaa aaccttttaa
     7921 ataatggaaa acattacgct cataaagctt aatacctttg tcaataatct tctctgtata
     7981 agcctcaaaa tagttggcat tataaaaaga agaatgctct aaacaatgct ggtaacaatt
     8041 gagggccaaa atcaaaacta atctcttatg gcgactaatc tcttggtaaa attcctccct
     8101 ctccataact tctctaccaa tccgagtgac atagtctaca tcgtagaaac tatagaggtt
     8161 accgaaaaga atcaactcat acatggtcca ttcttctgtt ttgaagagat aatctgctac
     8221 cttatccaaa tcatcctgct tcatatcata agtcgcatct ctttgacaaa tcagaccttg
     8281 tagcaaaatc cagttcagct caaaataaag ggaagtcgtc gaactcttag acttttcaag
     8341 ttgttctctt tgaagctttt gaaaacctgc aatatcgttt gaatagtaaa gtgggataat
     8401 ctgtgccatc atagacacat gttcatgatt atgaaaattc cttgccttat ccatgaaatt
     8461 ttcgattgtt acatgaatgt tatccaaaat ctcaaagaaa cgggagactg ccaggtcaga
     8521 ctccccaagc tcaaagcgag ataactgaga ggtagagcag gattcgcctg ctgcttcctt
     8581 taaagaataa tttccacttg ttcgaaattc acgaaatact tttccaagat gttccatctt
     8641 tacacctgat ctgataattc ttcccactca agcatagctt cttcctgacg atggctgatt
     8701 ttgtccagct cagcctgtaa ttccatgagt ttgtcggcat cgtttgtttc caacatttgt
     8761 tcagaaatgg cttggctttg actttctagc tcttcaattt cagcttctag actttcgatt
     8821 tgtcgcatga gtttgcgaac ttctttttga ctttctttct gggcctgata gtcattgact
     8881 ggacttgctt cctttgcttg attgctagtt gaagcttcct cagtctgact catttctgct
     8941 gttgctttct tctcaacata gtagtcgtaa tctccaaggt agagagttga accattctca
     9001 gacaattcca aaacatgagt tgccacacga ttgataaagt aacgatcatg actgacaaaa
     9061 agcaaggtac catcaaagtc aatcaaggca ttttctagca cttccttact atcaatatcc
     9121 aagtggttgg tcggctcatc cagaatcaaa aagttattgt tttccataga caatttagct
     9181 aaaagcaaac gagctttttc gccaccagat agcatgccga ctgatttttt aacatcatct
     9241 cctgagaaaa ggaaggcccc aagacggttg cggatttcaa cttctggtgt cagtttgaaa
     9301 tcattccaga gttcatccag caccgtatta cttggtgtca gcttgctttg ggtttggtca
     9361 tagtaaccaa cctcaacatt agcgccaaag cgcttttcac ctttgataaa aggaatctgg
     9421 tccacaatag acttgataaa ggttgacttg ccgataccat ttggaccaac gatagcgaca
     9481 gcattcatct tacgaagatc taggttgata ggttgtgaca aaacttcccc gtcataacca
     9541 atagcagtat tttcaacagt caaaacaaca ttgcccgacg ttttttcaga ctggaaggtc
     9601 atgttggctg ctttcttgcc agcttcaggc ttgtccaaac gctccatttt ttctagttgt
     9661 ttacggcgag attgagcacg tttggtcgtt gaagcacgaa ctagattgcg attgacaaag
     9721 tcttccagag cagcgatttc cttctgttgc ttttcatagt tttttgcctc agtagctagc
     9781 ttttgctcct tcaactcaac aaaacgagag taattcccca catagcgatc caaggaatac
     9841 ttggtcaaat ctagcgtaat tgtcgcaacc ttgtccaaga aataacggtc gtggctgacg
     9901 ataatgaggg caccgctata gtttaccaag taattctcta gccaggagat ggtttcaata
     9961 tccaagtggt tagttggctc gtccaagacc aagagattgg gcttttcaag gagcatttta
    10021 gctagagcca aacgagtatt ttgaccacca gaaagctcag caattttcat ctgccacata
    10081 gactcgtcaa acttgaatcc attcaaaatc gctcgaatat cagcttcata ggtaaagcca
    10141 cctgcttggc gaaaattttc agataagcgg tcataatctg acatcagttt atccaaatcc
    10201 tcaccagact tttcacccat ctccagctcc atctgacgca gttgtttatc tgtccgacgt
    10261 aagtcatcaa agacatgaag catctcatca tagatggtat tttcagactc aaaacggcta
    10321 tcttgagcta ggtaagacag agaaatatct tttttcttat tgatttctcc actagttggc
    10381 tcctcttctc caactaaaat cttcaaaaga gtagacttac ctgcaccatt tttcccaaca
    10441 agggcaatcc gatctcgttc atcaacctgc aggttgatat tatcgaaaag aacctctcct
    10501 gcaaaagaac gttcaatttt attagcttgt aaaataatca tacaagtagt atagcatgtt
    10561 tccctaaggc attcaagata atcgtaagtc ttttagtaca acttttataa cataaaataa
    10621 actaaattat gtatatttta tattagattc cttcactatc ttgttggatt ttctaaccag
    10681 ctaatcttgt ttcaaatagt tatcgcacaa gcctattatt taattctttt cattatttac
    10741 gtacgc
//
LOCUS       DAVLBE010000062        10694 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.062, whole genome shotgun sequence.
ACCESSION   DAVLBE010000062 DAVLBE010000000
VERSION     DAVLBE010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10694)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10694)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10694
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.062"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            <1..1960
                     /locus_tag="VXB91_001736"
     CDS             <1..1960
                     /locus_tag="VXB91_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="peptidase M26"
                     /protein_id="HEV0471149.1"
                     /translation="EALLLGLTYLERWYDFKYRDTKAKDLVMYHLDFFGKSNSSALDN
                     VIELGKSGYNNLLAKNNVITYNVLLAKNYKTNNLFDALEKYRKAFVPDKTNNEWFKEQ
                     TKAYIVEEKSTIKEVSDKQSIAGSPYSIGVYDRLTSPSWKYPSMVLPLLTLPEKSVFI
                     IANISTIGFGAYDRYRSKEHPAGTDLNDYVEKKAKEAAVRFRDHYDYWYRILDDKNKE
                     KLYRSVLVYDAFRFGTDEKEDKDTYQATFETNHPAIKHFFGPAGNNVVHNSNGAYATG
                     DAFYYMAYRMLDKDGAVTYTHEMTHNSDREIYLGGYGRRNGLGPEFYAKGLLQAPDHP
                     NDPTVTINSILKYDQSEESTRLQVADPTQRFGSVDDLNKYMHNMFDVIYMLEILEGKA
                     VAKLDTNQKYDLLRKIENEYKPDPDGNSVYATNVVRRLKPEELTKLTTFNSLIEHDII
                     TRRGYVDEATYKRNGYYTINLFSPIYSALSSKIGTPGDLMGRRIAFELLAAKGYKDGM
                     VPYISNQYEKEAKAQGKVITSYGKQIGLVTDEIVLSKVFNNQYNSWIDFKKDMYKERE
                     DKFGKLNKVSFIDPNGSWARQQKVTIDNINRLEKMIEDAVKFDAEDEVAKLYPETNSR
                     VLKLKKAIFKAYLDQTGDFRSSIFENKK"
     gene            2004..7217
                     /locus_tag="VXB91_001737"
     CDS             2004..7217
                     /locus_tag="VXB91_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEV0471150.1"
                     /translation="MSLLKKDKFSIRKIKGIVGSVFLGSLLFAPSVVGASTYHYLDYS
                     SLTQTERDQLKQGRPDESKESYALDYEKDALPNTGSSQSIMTALGLLAIGSLIVIITK
                     DNRNKKIATFLIVGATGLVTLSTASALNLNANIHESGRDGVLQISGYRYVGYLELDDK
                     TVSSVSPASTVSPVEQPKVVTEKGEPEVHEKPDYTQPIGANLVEPEVHEKLAYTEPVG
                     TTGVDENGNLIEPPVNDIPEYTEPVGTTGVDENGNLIEPPVSDIPEYTEPISTVSEVA
                     SEREELPSLHTDIRTETIPKTTIEESDPSKFIGDDSVRQVGEDGERQIVTSYEELHGK
                     KISDPVETVTILKEMKPKILVKGTKEKPKEKTAPVLTLDRTNTNVLNRSATLSYHLVN
                     TDGVTINKITATIKDGNEIVKTVDLTSEQLDKQVEDLKFYKDYKIETTMTYDRGKGEE
                     TATLEEKPLRLDLKKVEIKNIASTNLVKVNDDGTETPSDFMTEKPSDEDVKKMYLKIT
                     SRDNKVTRLAVDKIEEVTEEGKKLYKITAEAQDLIQHTDPTKVRNKYVHYIEKPVPKV
                     DDVYYNFKELVDAMNADKNGTFKIGADLNATNVPTPNKQYVPGTFKGHLSSVDGKQYT
                     IHNIARPLFDRVENGSVKNINLGNVDINMPWADGIAPVANMVKNATVEDVKVTGNVVA
                     NNNIAGIVNKIDSGGQLTNVAFIGNLTGVGDKGQYMAGIAGEIWRGNLAKAYVEADIV
                     ANRARIGGLVAKTDNGNDSMGIGKYGSIRKSVTKGTIKTKVLFETGGFINSNLPFGKL
                     EDNISMMRVENGEEFFGSSDLDYDGGYFTNGWLERNFVVKGVSSGKHSYKRSRDKIKE
                     ISQDEANKRIANFGLTADKYEINEPVVNRLNRLTRREDEYKSTQDYKSERDLAYRNIE
                     KLQPFYNKEWIVNQGNKLAEDSNLAKKEVLSVTGMKDGQFVTDLSDIDKIMVHYADGT
                     KEEMDVTKNTDSKVQQVREYSVSGLGDVVYTPNMVVKNRDKLIADVKSQLSSVELISQ
                     EVRDLMSRRDKPAENTDERKNGYIKDLYLEESFAEVKQNLDKLVKSLVENEDHQLNGD
                     EAAIKSLLKKVETNKAKIMMALTYLNRYYDIKYGDISIKNIMMFKPDFYGKTPSVIDR
                     LINIGSSEKNLKGDRTQDAYREIIAGNTGKSNLRNFLEYNMRLFTEDKDINDWFIHSA
                     KNVYVSEPKTTNTELKDKRHRVFDGLDNGVHGRMILPLLTLKDAHMFLISTYNTMAYS
                     SFEKYGKHTEEARNEFKTKIDEVAHAQQTYLDFWSRLALPNVRDRLLKSQNMVPTPVW
                     DNQTYNGSPVGRRGFDSKGNPIAPIRELYGPTWRHHDRDWRMGAMASIFPNPNNDDKV
                     LFMVTDMISPFGISAFTHETTHVNDRMLYFGGHKHRQGTDVEAYAQGMLQTPDSSTTN
                     GEYGALGINMAYHRPNDGNQWYNPDPDKLKTRDDIDRYMRNYNEAMMLLDHVEADAVL
                     PKIKGDNSKWFKKIDKEMRSKIQYNDLLGPNQWDSIRDLKDEEKVMTLSSVNDLVDNN
                     FMTKHGNPGNGRYRPEDFTPNSAYVNVNMMAGIYGGNTSQGAPGSLSFKHNAFRMWGY
                     YGYENGFISYVSNKYKAEADKNNHGLLSDKLIINKVSKGNFNTLEEWKRHWYGEVLAK
                     AKKGFEAIDIDGVHISNYDELRPLFDKAVEEDLKKPDDFSHTVALKSKVFKALLKNTD
                     GFFNKLFKEDI"
     gene            7471..8322
                     /gene="ylqF"
                     /locus_tag="VXB91_001738"
     CDS             7471..8322
                     /gene="ylqF"
                     /locus_tag="VXB91_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HEV0471151.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQGIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEEAPVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EDLDGND"
     gene            8309..9088
                     /locus_tag="VXB91_001739"
     CDS             8309..9088
                     /locus_tag="VXB91_001739"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HEV0471152.1"
                     /translation="MATIKEIKEFLVTVKELESPIFLELEKDNRSGVQKEISKRKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIVGIDEVGRGPLAGPVVAAAVILPKNCKIKG
                     LNDSKKIPKKKHLEIFQAVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFPGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKES"
     gene            9104..10654
                     /locus_tag="VXB91_001740"
     CDS             9104..10654
                     /locus_tag="VXB91_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HEV0471153.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLIVGIIVGSFRF
                     LIEKGFHLIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMPDNIPPMTLDQYWIYLVMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFILIIPVGIFLPQIIGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGALVGVICVNLGLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNVLITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
BASE COUNT         3666 a         1755 c         2178 g         3095 t
ORIGIN      
        1 agaagcttta cttctaggat taacatactt agagcgttgg tacgacttca aatatcgtga
       61 tacaaaagcg aaagatttag tcatgtacca cttggatttc ttcggtaaat caaatagttc
      121 agcgttagat aatgttatcg aactaggtaa atcgggatat aataacttac tagcaaaaaa
      181 taatgttata acttataatg ttttattagc gaaaaattat aagactaata atttatttga
      241 tgcattagag aaatatagaa aagcatttgt accagataaa acaaataatg agtggtttaa
      301 agaacaaact aaagcatata ttgtagaaga aaaatctact attaaagagg taagtgataa
      361 gcaatcaata gctggtagtc catattcaat tggagtatat gatagattaa ctagcccatc
      421 ttggaaatat ccaagtatgg tgttgccgct attaacatta cctgaaaaat cggtgtttat
      481 tatagccaac atttcgacta taggtttcgg tgcttatgat agatatagaa gtaaagaaca
      541 tccagcagga actgatttaa atgactatgt tgagaaaaaa gctaaagaag cggctgttag
      601 atttagagat cactatgatt attggtatag aatactagat gataaaaata aagaaaaatt
      661 atatagaagt gttctagtct atgatgcatt tagatttggt acagatgaaa aagaagataa
      721 agatacatat caagcaactt ttgaaactaa tcatccagct ataaaacatt tcttcggtcc
      781 agcgggaaat aatgttgttc ataattctaa tggagcatat gctacagggg atgcattcta
      841 ttatatggca tatcgcatgc ttgataaaga tggtgcggta acttatacac acgaaatgac
      901 acataactca gatagagaaa tttatcttgg aggctatgga agacgaaatg gacttggacc
      961 agagttttat gctaaaggac tgctacaagc tcctgatcat cctaatgatc caacagtcac
     1021 tattaattcc atattaaaat atgatcaatc agaagaatca acaaggcttc aagtagcaga
     1081 tccaactcaa cgatttggaa gtgttgatga tctaaataag tatatgcata atatgtttga
     1141 tgtaatatac atgcttgaaa tactagaagg taaagctgta gctaaattag atacaaatca
     1201 aaaatatgat ttattaagaa aaatagaaaa tgaatataaa cctgatcctg atggaaattc
     1261 tgtttatgca acgaatgttg tacgtagatt aaaaccagaa gaacttacta aattaactac
     1321 atttaacagt ttgatagaac atgatattat aacaagaaga ggttatgtag atgaagcaac
     1381 ttataagcgg aatggctact atacaattaa tctattctca ccaatttatt cagcattgag
     1441 cagtaaaata ggaacaccag gagatttaat gggacgacgt attgcatttg agttattggc
     1501 agccaagggg tacaaagacg gtatggttcc atatatttct aatcagtatg aaaaagaagc
     1561 gaaagctcaa ggaaaagtta ttacatcata tggtaaacaa ataggtttag ttactgatga
     1621 aattgttctt tcaaaagtat ttaataacca gtataattct tggatagatt tcaagaaaga
     1681 tatgtataaa gaaagagaag ataaatttgg aaagttaaat aaagttagtt ttatcgatcc
     1741 aaacggttct tgggctcgac aacagaaagt gactattgat aatattaata gacttgaaaa
     1801 aatgattgaa gatgcagtaa aatttgatgc tgaggatgaa gttgccaaat tatatcctga
     1861 gacaaatagt agagttctta aactgaaaaa agcaatcttt aaagcttatc ttgaccaaac
     1921 cggtgatttt agaagttcaa tttttgagaa taaaaaatag tgtttactat taggaaataa
     1981 aaagtgaagg tggaggatta gaattgtcat tattaaaaaa agataaattt tccattcgga
     2041 aaataaaggg tattgttggt tcggtattct tggggagtct tttatttgca ccgtcagttg
     2101 ttggtgcatc gacttatcat tacttagatt atagtagttt gacacaaact gaacgtgatc
     2161 aactcaaaca aggtagacct gatgaatcca aagagtcata tgctttggat tatgaaaaag
     2221 acgcactacc aaacacagga agttctcaat ctattatgac tgcattgggt ttgttagcta
     2281 tcgggagtct tattgtgatt atcacaaaag ataatagaaa taaaaaaata gctacatttt
     2341 tgattgtagg ggcgacaggt ttagttacac tatcaactgc ttcagcactt aatttgaatg
     2401 ctaacatcca tgagtctgga cgtgatggtg tgttgcaaat ttctggttac agatatgttg
     2461 gttacttgga gcttgatgat aaaactgttt cgtcggtttc tccagcatca actgtttcgc
     2521 cagttgagca acccaaagtt gtaacagaga aaggcgaacc ggaagttcat gagaagcctg
     2581 actatacgca accaataggt gcaaaccttg ttgagcctga agttcatgag aaactagcat
     2641 acactgaacc agtagggaca acaggagtag atgaaaatgg aaacttgatt gaaccacctg
     2701 ttaacgacat cccagaatat actgagccag taggtacaac aggagtggat gaaaatggaa
     2761 acttgattga gccacctgtt agcgacattc cagagtatac tgaaccaata tctacagttt
     2821 cagaagttgc atcagaaaga gaagagttgc cttctttaca taccgatatt cggacagaga
     2881 ctattcctaa aaccactata gaagaatctg atcctagcaa atttataggc gatgattctg
     2941 ttagacaagt tggtgaggat ggcgaacgtc aaattgttac tagctatgaa gagttacatg
     3001 gcaaaaaaat cagtgaccca gttgaaacag taactatttt gaaagaaatg aagcctaaaa
     3061 ttcttgtaaa aggtaccaaa gaaaaaccta aagaaaaaac ggctcctgtt ttgaccttag
     3121 atagaacaaa tacaaatgta ttaaaccgat ccgcaactct ttcttatcat ttagttaata
     3181 cagatggagt cacaatcaat aaaattactg cgacaattaa agatggaaat gaaattgtca
     3241 aaacagtaga tttgacttca gagcaattag ataagcaggt agaagattta aaattctaca
     3301 aggactataa gatagagacc actatgacct atgaccgtgg caagggagaa gaaactgcaa
     3361 cattagaaga gaaaccactt cgcttggatt tgaaaaaagt tgaaattaaa aatatcgcat
     3421 ctactaattt agtgaaggta aatgacgatg gtactgaaac acctagtgat tttatgactg
     3481 aaaaaccttc agatgaagat gtgaagaaaa tgtacttaaa aattactagt cgtgataata
     3541 aagtaacacg tttagcagtt gataaaattg aagaagtgac tgaagaaggt aagaaacttt
     3601 ataaaatcac tgccgaagct caagatttga ttcaacatac agacccaacg aaggttcgta
     3661 acaagtatgt tcattatatt gaaaaaccag ttccaaaagt tgatgacgtt tattataact
     3721 ttaaagagtt agtagatgcc atgaatgctg ataaaaatgg tacatttaaa atcggagcag
     3781 atttgaatgc aacgaatgta ccaacaccta acaaacaata tgttccaggt acgtttaagg
     3841 gacatctatc aagtgttgat ggtaaacaat atacaattca taacattgcc cgtcccttat
     3901 ttgaccgtgt tgaaaatggt tctgtgaaaa atattaattt aggtaatgtg gatatcaata
     3961 tgccttgggc tgacggaata gcacctgttg ccaatatggt gaaaaatgca actgttgaag
     4021 atgttaaggt aactggtaat gtagttgcta ataacaatat tgcgggtatc gtcaataaaa
     4081 tcgatagtgg tggtcagttg acaaatgtag ccttcatcgg taatcttaca ggtgttggtg
     4141 ataaaggtca atatatggct ggcattgccg gtgagatttg gagaggtaat cttgcaaaag
     4201 catatgtcga ggctgatatt gttgctaaca gagcccgtat aggtggttta gttgctaaaa
     4261 cagataatgg taacgactct atgggaattg gtaaatacgg ttcaattcgt aaatcagtca
     4321 ccaaaggaac cattaagact aaagttttgt ttgaaacagg tggatttatc aatagcaatc
     4381 ttccttttgg taaacttgaa gataatattt caatgatgag agttgaaaat ggtgaagagt
     4441 tctttggttc ttccgatttg gactacgatg gtggttattt cacaaatggc tggttagagc
     4501 gtaactttgt tgtcaaaggt gtcagttcag gtaagcattc atacaaacgt tctcgtgaca
     4561 aaattaaaga aattagtcaa gatgaagcta ataagagaat tgcaaatttt ggacttactg
     4621 ctgataaata cgaaatcaac gaacctgtgg tcaatcgctt aaatcgttta accagaagag
     4681 aagatgaata taagtcaact caagactaca aatccgaacg tgatttagct tatcgtaata
     4741 ttgagaaact tcaaccattt tataataaag aatggattgt caaccaaggt aacaaacttg
     4801 cagaagattc aaacttagct aagaaagaag tcctttctgt tacggggatg aaggatggtc
     4861 aattcgtgac cgatttatca gatattgata agattatggt tcactatgct gatggtacta
     4921 aggaagaaat ggatgttact aagaatactg attctaaagt ccaacaagtg cgtgaatata
     4981 gtgtatctgg tcttggtgat gttgtttata caccgaatat ggttgttaaa aatcgtgata
     5041 aattgattgc tgatgttaaa tctcaattat caagtgtgga attgatttca caagaagtaa
     5101 gagatttaat gagtagacgt gataaacctg cagagaatac ggatgaacgt aagaatggtt
     5161 atattaaaga tctatactta gaagaaagct ttgccgaagt gaagcaaaat ctagataagt
     5221 tagtcaaatc cttggtcgaa aatgaagacc atcaattgaa tggtgatgaa gctgcgataa
     5281 aatcacttct caagaaagtg gaaaccaata aagctaaaat catgatggct ctgacttatc
     5341 tcaatcgtta ctatgatatc aaatacggtg acataagtat aaaaaacatc atgatgttca
     5401 aacctgattt ttatggtaaa acaccaagtg ttattgacag actcatcaac atcggttcaa
     5461 gtgaaaagaa cttgaaaggg gatcggactc aggatgctta ccgtgaaatc atcgcaggta
     5521 atactggtaa aagtaatttg cgtaacttct tagaatacaa catgcgtctg tttacagagg
     5581 ataaagacat caatgattgg tttatccact cagctaagaa tgtttatgtt tcagaaccta
     5641 agacaacaaa tacagagttg aaagataaac gtcatcgtgt gttcgatggt ttagataacg
     5701 gtgttcatgg tcgtatgatt ttaccacttc taacgcttaa agatgcccat atgttcttaa
     5761 tttcaacata taacacgatg gcgtacagtt catttgagaa atatggaaaa catacagaag
     5821 aagctcgtaa tgagttcaaa actaagattg atgaagttgc acatgctcaa caaacttatt
     5881 tagatttctg gtccagatta gctctgccta atgttcgtga tagacttctt aagagtcaaa
     5941 atatggtacc gacaccagtt tgggataacc agacctacaa tggttctcct gtaggtcgtc
     6001 gaggatttga cagtaaaggt aaccctatag ctccaattcg tgaattatat ggtccaacat
     6061 ggcgacacca tgatagagac tggcgtatgg gcgctatggc atcaatattc cctaatccaa
     6121 ataatgatga caaggtcttg tttatggtga cggatatgat tagcccattt ggtatttcag
     6181 cctttactca cgaaacaaca cacgtaaacg atagaatgct ttacttcggt ggtcataagc
     6241 atcgtcaagg tacagacgtt gaagcctatg ctcaaggtat gttgcaaaca cctgacagct
     6301 caacgactaa tggtgaatac ggcgcacttg gaattaacat ggcttaccat cgtccaaatg
     6361 atggtaacca atggtacaac ccagatcctg acaaattaaa gacacgtgat gacattgacc
     6421 gctacatgag aaactacaat gaagctatga tgttgcttga tcatgtagaa gctgatgctg
     6481 tacttcctaa aattaaagga gacaatagta agtggttcaa gaagattgac aaagaaatgc
     6541 gctctaagat tcagtataat gatcttttag gtccaaacca atgggatagt atccgtgatt
     6601 tgaaagatga agaaaaggta atgactttat ctagcgtcaa tgatttagtg gataataact
     6661 tcatgacaaa acatggaaat ccaggtaatg gacgttatag accagaagat tttacaccaa
     6721 actcagctta cgtaaatgtc aatatgatgg caggaattta cggtgggaat acgagtcaag
     6781 gtgctcctgg ttcattatca tttaagcaca atgctttccg tatgtggggc tattatggtt
     6841 atgaaaatgg ctttattagt tatgtatcaa ataaatacaa agcagaagca gataaaaaca
     6901 accacggttt actaagcgat aagctaataa ttaataaagt atcgaaagga aactttaata
     6961 ctcttgaaga gtggaagaga cattggtacg gggaagttct tgctaaagct aagaaaggtt
     7021 ttgaggctat cgatattgat ggcgtccata tcagtaacta tgatgagtta aggcctttat
     7081 ttgataaagc agttgaagaa gatttgaaga aaccagatga cttctctcac actgttgctc
     7141 ttaaatctaa ggtcttcaaa gcccttctta aaaacacaga cggtttcttt aataaactgt
     7201 ttaaagaaga catttaaatg tttagaatat agaaggaaca gttttttgct ccctctgaaa
     7261 agtcatcatt tgatggcttt tttctatata gggtacttga aaggctatca tcggacaaaa
     7321 taaagaaggc atgatataat ataaggtaga tttctatgcc ataaaacaaa aaactgtttg
     7381 aacatcattc atttgagaac cctttatgtt caaacgatag taaaataaaa taggatctct
     7441 aaacccttgc tacgaaagga aaaaaactca atggctacta ttcaatggtt tcctggtcac
     7501 atgtctaaag cgcgtcgaca ggtgcaggaa aatttaaaat ttgttgattt tgtaacgatt
     7561 ttggtggatg cacgcttacc tctatctagt caaaatccta tgttgaccaa gattgttggt
     7621 gataaaccaa aactcttgat tttaaataag gcggatttgg ctgatccagc aatgaccaag
     7681 gaatggcgtc agtattttga atcacaagga atccaaactc tggctatcaa ctccaaggag
     7741 caagtgactg taaaagttgt aacagatgcg gccaagaagc tcatggctga taagattgct
     7801 cgccagaaag aacgtgggat tcagattgaa accttgcgta ctatgattat cgggattcca
     7861 aacgctggta aatcaactct gatgaaccgt ttggctggta aaaagattgc tgttgttgga
     7921 aacaagccag gggtcacaaa aggtcaacaa tggcttaaaa ccaataaaga cctggaaatc
     7981 ttggatacac cggggattct ctggcctaag tttgaggatg aaactgttgc acttaagttg
     8041 gcattgactg gagctatcaa ggatcagttg cttcctatgg atgaggttac catttttggt
     8101 atcaattatt tcaaagaaca ttatccagaa aagctggctg aacgcttcaa acaaatgaaa
     8161 attgaagaag aagcgcctgt gattattatg gatatgaccc gcgccctcgg tttccgtgat
     8221 gactatgacc gtttttacag tctcttcgtg aaggaagtcc gtgatggcaa actcggtaac
     8281 tataccttag atacattgga agacctcgat ggcaacgatt aaagaaatca aagaattcct
     8341 tgtgacagtc aaggagttag aaagccctat ttttttagag cttgaaaagg ataatcgctc
     8401 aggagttcaa aaggaaatca gcaagcgtaa aagagccatt caagctgaat tagatgaaaa
     8461 tttgcgcttg gaatccatgc tttcttatga aaaagaactt tataagcaag gattgacctt
     8521 aattgtaggt attgatgagg ttggtcgtgg tcctcttgct ggtcctgtag tcgctgcggc
     8581 cgtcatttta cctaaaaatt gtaagattaa aggtctcaac gacagcaaga aaattcctaa
     8641 aaagaaacat ctggagattt tccaagccgt tcaagaccaa gccttgtcga ttggaattgg
     8701 tatcatagat aatcaggtca tcgaccaagt caacatctat gaagcaacca aactagccat
     8761 gcaagaagca atctcccagc tcagccctca accagagcac cttttgattg atgccatgaa
     8821 actggacttg cccatttcac aaacctccat tatcaaagga gatgccaact ccctctctat
     8881 cgcagcagca tctatagtag ccaaggtaac acgtgatgaa ttgatgaagg aatacgatca
     8941 gcagttccct ggctatgatt tcgctactaa tgcaggatat ggcacagcta aacatctgga
     9001 aggcctcaca aaactaggag ttaccccaat tcaccgaacc agctttgaac ccgttaaatc
     9061 actggtttta ggtaaaaaag aaagttaatt gaaaggaaat accatggagg aacagtcgga
     9121 aatagtccgt tctaagaaag aattcgcctt tgcatccagc actatactat cccaagttgg
     9181 tcgaggaatc attgtcggcc tcatcgttgg aattatcgtc ggatcctttc gtttcttaat
     9241 tgaaaagggc ttccacctga tacaaggagt ttatcaagat caagggtact tagtgcgcaa
     9301 tctttttgta ctggttttgt tttatatact catctgttgg ctcagtgcca aactaacacg
     9361 gtcagaaaaa gatattaaag gctcaggaat tcctcaagtc gaagccgaac tgaaaggcct
     9421 catgtccctc aactggtggg gcattctttg gaaaaaatat gtgctaggta ttcttgctat
     9481 tgccagtgga ctcatgctgg gtcgagaggg acccagtatt caacttggag cagttggtgg
     9541 taaaggaatt gccaagtggc tcaaatccag tccagtagag gaacgttcct tgattgccag
     9601 tggagctgca gcaggtttag ccgcagcctt taatgctcct attgcagcac ttctctttgt
     9661 tgtagaagaa gtctatcacc atttttcgcg ctttttctgg gtctcaactc tagcagccag
     9721 catcgtagca aactttgtgt ctctactcat gttcggtttg acaccagtat tggatatgcc
     9781 agataacatt cctcccatga ccctagatca gtattggata tatctcgtca tgggaatttt
     9841 ccttggattt tcaggttttc tctatgagaa agctgtatta aacgttggaa gagtttatga
     9901 cttgattggt caaaaaatcc atttggatag ggcttattat cccatcttgg cttttatcct
     9961 tatcatacca gtcggaatct tcttacctca aatcattggt ggcggaaatc agcttgtcct
    10021 ttctttaact gaacaaaatt ttagtttcca agttttatta gcttactttt taatccgctt
    10081 tatttggagt atgattagct atggaagtgg actgccagga ggaattttcc tccccatttt
    10141 agctcttggt tctttgcttg gtgccttagt tggtgttatc tgtgtcaatc ttggacttgt
    10201 cagtcaagag caattcccta tatttgtcat tctaggaatg agtggctatt ttggagccat
    10261 atcaaaagct cccttaaccg ctatgatcct cgtaactgag atggtaggag atattcgcaa
    10321 ccttatgcca cttggtcttg tcactcttgt ttcttatatt atcatggatt tgctcaaagg
    10381 tacgccagtc tatgaagcca tgctggaaaa aatgcttcca gaagaagtat ctagcgaagg
    10441 agaagttaca cttatcgaaa taccagtttc tgataaaatt gctgggaaac aagttcatga
    10501 actcaactta ccacacaacg tcctcatcac aactcaagtc cataatggca agagccaaac
    10561 agttaacggc tcaaccagaa tgtatctggg tgatatgatt cacctggtta ttccaaaaag
    10621 tgaaattgga aaagtcaaag atttgttgtt gtagtatgat catttacata atttatgtta
    10681 tgtaaatgat cagt
//
LOCUS       DAVLBE010000063        10639 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.063, whole genome shotgun sequence.
ACCESSION   DAVLBE010000063 DAVLBE010000000
VERSION     DAVLBE010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10639)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10639)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10639
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.063"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            69..566
                     /locus_tag="VXB91_001741"
     CDS             69..566
                     /locus_tag="VXB91_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HEV0471154.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTTWDFTM
                     FEEKS"
     gene            566..2221
                     /gene="dnaX"
                     /locus_tag="VXB91_001742"
     CDS             566..2221
                     /gene="dnaX"
                     /locus_tag="VXB91_001742"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HEV0471155.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYAPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVSLADIK
                     SSLQPKIYAEMMTVRLAEIKPEPALSGAVENEIATLRQEVARLKQELSNVGAVPKQVA
                     PAPSRPATGKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLVGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQTEKEVEESLIPEGFEFLADKVKVEED"
     gene            2249..2443
                     /locus_tag="VXB91_001743"
     CDS             2249..2443
                     /locus_tag="VXB91_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HEV0471156.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            2593..3363
                     /gene="sufC"
                     /locus_tag="VXB91_001744"
     CDS             2593..3363
                     /gene="sufC"
                     /locus_tag="VXB91_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HEV0471157.1"
                     /translation="MSVLEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEGDEKISVREFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            3391..4653
                     /gene="sufD"
                     /locus_tag="VXB91_001745"
     CDS             3391..4653
                     /gene="sufD"
                     /locus_tag="VXB91_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HEV0471158.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFH
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKISYLERLESRGEGSDKATANITVEVIARSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLIGNGSHADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            4664..5890
                     /locus_tag="VXB91_001746"
     CDS             4664..5890
                     /locus_tag="VXB91_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEV0471159.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATASYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVAR
                     FAEEILTEGDQVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVVNPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQSASWKELPWKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAVEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLEVPATARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            5877..6317
                     /locus_tag="VXB91_001747"
     CDS             5877..6317
                     /locus_tag="VXB91_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HEV0471160.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQISLNNPTCGDVI
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDAVLGKTKQEILELATIFSEMVQGQ
                     KDERQDQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            6371..7783
                     /gene="sufB"
                     /locus_tag="VXB91_001748"
     CDS             6371..7783
                     /gene="sufB"
                     /locus_tag="VXB91_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HEV0471161.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVIRELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFNQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(7982..9223)
                     /locus_tag="VXB91_001749"
     CDS             complement(7982..9223)
                     /locus_tag="VXB91_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEV0471162.1"
                     /translation="MKKIFLTLLTVSLLGGASTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITVYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFVDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKTPVQDGKEDTVTAVAPEDIYLIERV
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYEDKDLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            9326..10435
                     /locus_tag="VXB91_001750"
     CDS             9326..10435
                     /locus_tag="VXB91_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEV0471163.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVSVLNTIMIP
                     FLLGGFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
BASE COUNT         3147 a         1946 c         2318 g         3228 t
ORIGIN      
        1 aaaatccttt gtttactaaa caagggattt ttcttttgtc tctgctcctt ttttgatata
       61 atagttctat gttaaaatca gaaaaacaat cacgttatca aatgttaaat gaagaattgt
      121 ccttcctatt ggaaggcgaa accaatgttt tggctaatct ttccaacgcc agtgctctca
      181 taaaatcacg ttttcctaat accgtatttg caggctttta tttgttcgat ggaaaggaat
      241 tggttttagg ccccttccaa ggaggtgttt cctgcatccg tattgcacta ggcaagggtg
      301 tttgtggtga ggcagctcac tttcaggaaa ctgttattgt tggagatgtg acgacctatc
      361 tcaactatat ttcttgtgat agtctagcta aaagtgaaat tgtggtgccg atgatgaaga
      421 atggtcagtt acttggagtt ctggatctgg attcttcaga gattgaggat tacgatgcta
      481 tggatcgaga ttatttggaa caatttgtcg ctattttgct tgaaaagaca acatgggact
      541 ttacgatgtt tgaggaaaaa tcttaatgta tcaagcactt tatcgaaaat atagaagtca
      601 aaacttctcc cagttagttg gtcaagaagt tgtggctaag actcttaaac aagcggtgga
      661 gcaagagaaa ataagtcacg cttatctttt ttctggtcct cgtggaacgg gaaaaaccag
      721 tgttgctaaa atctttgcca aggctatgaa ctgtcccaat caagtgggtg gcgaaccttg
      781 caataactgc tatatttgtc aagcagtgac ggacggtagt ttagaagatg tcattgaaat
      841 ggatgcagct tctaataatg gggtagatga aattcgcgaa attcgtgata aatctaccta
      901 tgcgcctagc cttgctcgtt ataaggttta tatcatagat gaggttcaca tgctgtctac
      961 aggggctttt aatgccctcc taaagacgct ggaagaacca acacagaatg tagtctttat
     1021 tttggccact actgaattgc acaagattcc tgctactatt ctatcccgtg tgcaacgttt
     1081 tgagtttaaa tcaattaaga cacaggatat taaggaacat attcactata tcttagaaaa
     1141 agaaaatatc agttctgaac cagaggctgt ggaaatcatt gccaggcggg cggaaggtgg
     1201 aatgcgggac gccttgtcta ttttggatca agccctgagt ttgacacagg gaaatgagct
     1261 gacgactgct atctctgaag aaattactgg caccattagc ctatcagcct tggatgatta
     1321 tgtggcggcc ttgtctcaac aggatgttcc caaagctttg tcttgcttga atcttctttt
     1381 tgacaatggt aagagcatga ctcgttttgt gaccgatctt ttgcactatt taagagactt
     1441 gttaattgtt caaacagggg gagaaaatac tcatcatagt tcagtctttg tagaaaattt
     1501 ggcacttcct caaaaaaatc tgtttgaaat gattcgctta gcaacagtga gtttagcaga
     1561 tattaagtct agtttgcagc ccaagattta tgctgaaatg atgaccgtcc gtttggcgga
     1621 aatcaagccc gaaccagctc tatcaggagc ggttgaaaat gaaattgcta cgctgagaca
     1681 ggaagttgcc cgtctcaaac aagagctttc taatgtaggt gcggttccta aacaagttgc
     1741 accagctcct agtcgaccag ctacgggcaa aacagtctat cgtgtcgatc gcaataaagt
     1801 gcaatctatc ttacaagagg ccgtcgaaaa tcctgattta gcacgtcaaa atctaattcg
     1861 tttgcagaat gcctggggag aggtaattga aagtctaggt gggccggaca aggctctgct
     1921 agttggttct caaccggttg ctgccaatga acaccatgct attcttgctt ttgagtctaa
     1981 cttcaatgct ggtcaaacta tgaaacgaga caatctcaat accatgtttg gtaatatcct
     2041 cagtcaggcg gcaggttttt cacctgagat tttagctatt tccatggagg aatggaaaga
     2101 agttcgcgca gccttttcag ccaaagccaa atcttctcaa actgaaaaag aagtagaaga
     2161 aagcctgatt ccagaaggat ttgaattttt ggctgataaa gtgaaggtag aggaagacta
     2221 aagaaagatt tcatgataca ataagtttat gaataaacaa caatttatta ttatggcgct
     2281 gtttacagct gctgagacct attttttcaa tgaagcctgg atgactggcc gctatattat
     2341 ggcagccttt tgggcaattt tactctttag aaatttccga gtcagttatg tgatgggcaa
     2401 aatcgttgat gtcatcgatc agcattttaa taggaaagac tagccctcag cttccagaca
     2461 aaatcaaagc cttttaggct tttttttgtt atactagaaa agtatattta tagaattttt
     2521 gctctatttc tggggaaatc agacgttttt ctagtaagta ctgtaaaagt tttgaaaaag
     2581 aaaggaacta tcatgtcagt attagagatt aaagatcttc acgttgagat tgaaggaaaa
     2641 gaaattttaa aaggggttaa cctgaccctg aaaacaggag aaattgccgc tatcatggga
     2701 ccaaatggta caggtaaatc gactctttct gccgctatca tgggaaatcc aaactatgaa
     2761 gtaactaaag gtgaagtttt gtttgatggc gtaaacatcc ttgagttgga agtggatgag
     2821 cgtgcgcgta tgggactttt ccttgctatg caatacccat cagaaatccc tggaattacc
     2881 aatgctgagt ttcttcgtgc cgctatgaat gcgggtaaag aaggtgatga gaagatttca
     2941 gttcgtgagt ttattactaa gctagatgaa aaaatggaat tgctcaacat gaaagaagaa
     3001 atggcagagc gttacctcaa cgaaggcttc tctggtggtg agaaaaaacg caatgaaatt
     3061 cttcaacttt tgatgttgga gccaacattt gctcttttgg acgagattga ctcaggtctt
     3121 gatattgacg ctcttaaagt tgtgtctaaa ggtgtcaatg ccatgcgtgg tgaaggtttt
     3181 ggtgctatga tcatcactca ctaccaacgt cttttgaact atatcacacc tgatgtggta
     3241 cacgtgatga tggaaggtcg tgttgtcctt tctggtggtc cagaattggc tgcgcgtttg
     3301 gaacgtgaag gatacgcaaa attagctgaa gaacttggct acgactacaa ggaagaattg
     3361 taatttcctc gtatctttta ggagaagtaa atgactagag aaaatattaa acttttttca
     3421 gaaatgcacg ctgaaccaag ctggttggct gatctccgtc aaaaagcttt tgacaagatt
     3481 gagactttgg aattaccagt tattgagcgt gtcaaattcc accgttggaa tctgggtgat
     3541 ggaacgatta cagaaaatga gccatcagca aatgttccag atttcacagc tttagatcat
     3601 cacttgaagt tggtgcaagt aggaactcaa actgttttcg aacaaactcc agttgagtta
     3661 gctgaacagg gtgttgtctt cacagacttt cactcagctt tagaagaaat tccagagctg
     3721 atcgaagaat tcttcatgtc atctgttaag tatgatgatg acaagttggc ggcttaccac
     3781 acagcttact ttaacagtgg tgctgtactc tatattccag ataacgtaga aatcacagag
     3841 ccaattgaag gaattttcta ccaagatagc gatagcaatg tgccgtttaa caagcatatt
     3901 atgattatcg ctggtaaaaa ttctaagatt agttatctgg agcgtttaga gtcacgcggt
     3961 gaaggaagtg acaaagcaac tgccaatatc acagtggaag tgattgcacg ttctggtgcg
     4021 caagtcaagt ttgctgctat tgaccgtcta ggtgaaaacg tcactgccta cattagccgt
     4081 cgtggtaaat taggcaacga tgcaagtatt gactgggcta tcggtgtcat gaacgaagga
     4141 aatgtcgttg ctgattttga tagtgacttg attggtaatg gtagccatgc tgacctcaag
     4201 gttgtagctc tttcaagtgg tcgtcaggta caagggattg atactcgtgt aactaactat
     4261 ggctgcaact ctatcggaaa tatcctacaa catggggtta tccttgaaaa agcaactttg
     4321 actttcaatg gtatcggcca catcatcaag ggtgctaagg gagcagatgc ccaacaagag
     4381 agccgtgttc tcatgctttc agaccaagcg cgttcagatg ctaacccaat tcttttgatt
     4441 gatgaaaatg acgtcactgc aggacatgca gcctctattg gtcaggtaga tccagaagat
     4501 atgtactacc tcatgagtcg tggattggat aaggcaactg cagagcgttt ggttgttcgt
     4561 ggtttccttg gatctgttat cgtggagatt ccagtcaagg aagttcgtga tgaaatgatt
     4621 gcaactatcg aagagaaatt gtcaaaacgc taaggggaag cctatgttag atgtagaagc
     4681 gattcgcaag gattttccaa ttttagatca gattgtcaat gatgaacctc tggtctatct
     4741 ggacaatgct gcgacgacac aaaaaccact agtagttctg aaagctatta acagttacta
     4801 tgagcaggac aatgccaatg ttcaccgtgg tgtccatacc ttagcggaac gagcgacagc
     4861 ttcttatgaa gctgctcgtg aaaccattcg taagtttatt aatgcaggct ctacaaagga
     4921 agttctcttt accagaggaa cgacaaccag ccttaactgg gtggcacgct ttgctgagga
     4981 aattctcact gagggagacc aggtcttgat ttcagtaatg gaacaccatt ctaatatcat
     5041 tccatggcag gaagcttgtc gaaagactgg agcagagctt gtctatgtct atcttaaaga
     5101 cggtgccttg gatatggagg atttgcgagc taaattgact gataaggtta aatttgtttc
     5161 cctagctcat gcctccaatg ttcttggtgt ggtcaatccg atcaaggaaa tcactcaatt
     5221 agcccaccaa gttggggcaa tcatggtagt ggatggtgct caatctacac ctcatatgaa
     5281 gattgatgtc caggacttgg atctggactt tttcgccttt tcgggtcaca agatggctgg
     5341 tccgactggt atcggtgtcc tttacggcaa agaaaagtat cttgagcaaa tgtctccagt
     5401 agaatttggc ggcgagatga ttgattttgt ctacgagcaa tctgctagtt ggaaggaatt
     5461 gccttggaaa tttgaggctg gaacgccaaa tatggcagga gctattggac ttgcgactgc
     5521 agttgattat ctggaaaaga ttggtatgga tgccgttgaa gctcatgaac aggaattgat
     5581 tgcgtacgtc tatccaaaac tgcaggcaat tgagggattg accatttacg gttctcagga
     5641 tttggctcaa cgttcgggtg ttattgcctt taacctaggt gatctccatc ctcacgatct
     5701 tgcgacagct ctggattatg aaggagtggc tgttcgtgct ggtcaccatt gtgcgcaacc
     5761 cttgcttcag tatttggaag tcccagcaac agctcgtgca agtttttata tctataatac
     5821 caaggcagat tgcgacaaac tagtcgatgc cctacaaaag acaaaggagt ttttcaatgg
     5881 cactttctaa actagatagc ctttatatgg cagtggtagc agaccattcg aaaaatccac
     5941 atcaccaagg gaagttagaa gacgctgagc aaatcagtct caacaatccg acttgtggag
     6001 atgtcatcaa tctctctgtc aagtttgatg cagaggaccg tttggaagat attgcttttc
     6061 taaattcagg atgcacgatt tcaactgctt ctgctagtat gatgacagat gccgttttag
     6121 gaaaaaccaa acaagaaatt ttagaactgg cgactatttt ttctgaaatg gttcaagggc
     6181 aaaaagatga gcgtcaagac caacttggag acgcggcatt cttgtcaggt gttgccaaat
     6241 tccctcaaag aatcaagtgt gcaaccctag cttggaatgc ccttaagaaa acaattgaaa
     6301 atcaagaaaa acagtaagac aagtttcttt tgtcttatga attattagaa atgaagaaag
     6361 aaaggatatt atggctgaag aaagagtaga accaaaacca attgaccttg gtgaatataa
     6421 atttggtttc catgacgatg tagagcctgt cttatcgaca ggaaaaggac tcaacgaagg
     6481 tgttattcgt gaattatctg ctgctaaggg tgagcctgag tggatgttgg agttccgttt
     6541 gaagtcttat gaaaccttca aaaaaatgcc catgcaaact tggggagcag acttgtcaga
     6601 gattgacttt gatgacttaa tctactacca aaaaccatct gacaaaccag cccgttcttg
     6661 ggatgatgta cctgaaaaga ttaaagaaac ctttgaacgt atcgggattc cagaagctga
     6721 acgtgcttat ttagcagggg cttctgccca gtacgagtca gaagtggttt accacaacat
     6781 gaaggaagag ttccaaaaat taggtattat ctttacagat acagattccg cactcaagga
     6841 atacccagac ttatttaatc aatactttgc gaagttggta ccgccgacag ataacaagtt
     6901 ggcagccctc aactcagcag tatggtcggg tggaactttt atctacgtgc caaaaggtgt
     6961 caaggtagat attccacttc aaacttattt ccgtatcaat aacgaaaata taggtcagtt
     7021 cgaacgtacc ttgattatcg ttgatgaggg agcaagcgtc cactacgtag aaggatgtac
     7081 agcaccaaca tattcaagca atagcttaca cgctgccatt gtagaaattt ttgctttgga
     7141 cggagcttat atgcgttata caactatcca aaactggtct gataacgtct ataacttggt
     7201 aacaaagcgt gctaaggctc aaaaggatgc cactgttgag tggattgatg gaaacttggg
     7261 tgccaaaacg actatgaaat atccatctgt ttaccttgat ggagaaggag cgcgtggtac
     7321 catgctctct atcgcctttg ctaatgcagg gcaacaccaa gacacgggtg ctaagatgat
     7381 tcacaatgct ccacatacca gctcgtctat tgtgtctaaa tccatcgcta aaggtggagg
     7441 aaaggttgac taccgtggac aagtcacctt taacaagaac tctaagaaat ctgtttccca
     7501 cattgaatgt gataccatta tcatggatga cttgtcagca tcagatacta ttccatttaa
     7561 tgaaattcac aactcgcaag tggctttgga acacgaagcc aaagtatcta agatttcaga
     7621 agagcaattg tattatctca tgagccgtgg attgtcagaa tctgaggcaa ctgaaatgat
     7681 tgtcatggga tttgtagaac cctttacaaa agaacttcca atggaatacg cagttgagct
     7741 gaaccgcttg attagctatg aaatggaggg atcagttgga taaaatttga ttttatactc
     7801 ttcgaaaatc tcttcaaacc acgtcagcat cgccttaccg tatgtatggt tactgacttc
     7861 gtcagtttca tctacaacct caaaacagtg ttttgagcaa cctgcggcta gcttcctagt
     7921 ttgttctttg attttgaaga tgaacttgta tcaaaaaatc gcggtttaaa atcgcgattt
     7981 tttataattt ctcgttaaca aagcggacaa actgattcca ccaaactttt aagaagaagg
     8041 ctttttcaat tttcttgtct gctaccattt cgaaactagg gcgctctgtg gtgatgtaac
     8101 cttgaccaat caagtccttg tcttcataag tcaaatggcc aaccactgtt ccagcttcaa
     8161 gtggtgctgg gattgctttg gaatcaggtg tgaattgaac agattgggaa gattgattcc
     8221 caacacgttc tattagatag atatcctctg gagccactgc agttactgta tcttcttttc
     8281 catcttgtac aggggttttg ctatcttgat aggcatcgcc ttgttgaacg attttgcgaa
     8341 gtgtaaatgt agaagaaata taatccatta gggaagatgt agctgtaaat cgagcgtaag
     8401 gattattgtc ttgatgatct gcatttaaaa caactgtgat gactctcatg cctttttcga
     8461 cagtagtacc aacaaaagac tctccagcct tatctgttgt tcctgttttt agcccatcaa
     8521 aaccaccacg gtaagcaggc ataccttcta acatgtagtt ggttgaagtg attgtcatcc
     8581 cagcaaaagt agaagaaggt tttttggtga tttctaagac ttgtgggtat tttttgatga
     8641 ggttgcgagc aacgatagcg acatcataag cactaagctt attttcctca tcttttttag
     8701 aacctgggta aatgttatcc cctagagttt cattgttaag acctgtcgta ttgacaacag
     8761 tggcatcctg aattccccat tccaagagtt ttgcccgcat catatcgacg aaatcttttt
     8821 ctgagccagc aattttctca gctagggcaa tagcggcgct gttggcacta gataccagag
     8881 ttgcttcaag caactcttcg acagtataat tacgggcctc cataggaata ttactggctt
     8941 cagaatttgt cgtcaattga taaggataat cagaaatatc tacaggagtg gagagggtaa
     9001 tacttccgtt ttccaaagct tcatagacca gataaacagt aatcaatttt gttatggaag
     9061 caatttcgac aggttgcgtt gcatccttct catagagaat tttaccagta tttgcctcaa
     9121 cagcaatcgc atgtttagcg gcaatggtaa aatcttgagc aacagcagta gaagcacccc
     9181 ctaaaagaga gacagttaac aaagttaaaa atattttttt catagtagtc ttattctatc
     9241 ataaagaaaa aaaatattct tgctttaata attcatctgt taagcttttt gaaaatatgg
     9301 taaaataaag tgagggaggt aactcatgtt tcgtagaaat aaattatttt tttggaccac
     9361 agaaatttta ctcttaacca tcatctttta cctatggaga cagatgggat ctttgattaa
     9421 cccttttgtt agcgtgctta atacaattat gattccattt ttattagggg gctttcttta
     9481 ttatttgaca aaccctattg ttactttctt aaataaagtc tgtaaactca atcgtttgct
     9541 tggtatttta attaccttgt gtactttggt ctggggaatg gtcataggtg ttgtctatct
     9601 cttacctatt ttgattaatc agttatctag tttgattata tctagtcaaa ctatttatag
     9661 tcgagtacaa gacttaatca tagacttatc taattatcct gcgctccaga atttggatgt
     9721 agaagctaca attcagcagt taaacttatc ctatgttgat attcttcaaa atatcctaaa
     9781 tagcgtatca aatagtgtgg ggagcgtctt gtcagctctt atcagtactg ttttgatttt
     9841 gattatgact ccagtttttt tggtttattt cttattagat ggacataaat tcttgcccat
     9901 gcttgaaaga acgattctaa agagggatcg cttgcatatt gcaggcttat taaagaattt
     9961 aaatgcgacg attgctcgct atattagtgg agtttcgatt gacgcaatca ttataggttg
    10021 tttggcttat attggctata gtattattgg tttaaaatat gctttagttt ttgccatttt
    10081 ttctggtgta gccaatttaa ttccttatgt ggggccaagt attggtttga ttcctatgat
    10141 catcgcaaat atattcactg atccccatag actgctgatt gcagtgattt atatgcttgt
    10201 tgttcagcag gtagatggca atatcttata tcctcgaatt gtaggaagtg ttatgaaggt
    10261 tcatccaatc acgattttag ttttactttt gttgtcaagc aatatctatg gtgtagttgg
    10321 aatgattgtc gcagtgccaa cctattctat cttgaaagaa atttctaagt tcttatcccg
    10381 tttgtatgaa aatcataaaa taatgaaaga acgagaaaga gaattagcta agtaaaagtc
    10441 aggagaaccc tgatttttct ttactggaag tggcctttag attagaagac tgaaaataag
    10501 ttaaagtctt aaactaattt tcacagctaa gaatagtaga agttaatctg ataaaaatcg
    10561 aaaaaaccag tggaattccg tgtcagggta agttccactg gttttcatag tctattaaag
    10621 ttcgaatgaa acctattta
//
LOCUS       DAVLBE010000064        10020 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.064, whole genome shotgun sequence.
ACCESSION   DAVLBE010000064 DAVLBE010000000
VERSION     DAVLBE010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10020)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10020)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10020
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.064"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            178..390
                     /locus_tag="VXB91_001751"
                     /pseudo
     CDS             178..390
                     /locus_tag="VXB91_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            290..736
                     /locus_tag="VXB91_001752"
     CDS             290..736
                     /locus_tag="VXB91_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEV0471164.1"
                     /translation="MRKHGLISKSTSKGYYQVAIPFMRLFCLVLVSIDYINCLSETTD
                     KNWHKSDRIFVTNTGKPVHSSILSKSLQRANERLKKPIPKHLSPHIFRHTTISILSEN
                     KIPLKTITDRVGHSDSEVTTSIYTHVTKNMKDEAINVLDKVMKKIF"
     gene            complement(874..2178)
                     /gene="eno"
                     /locus_tag="VXB91_001753"
     CDS             complement(874..2178)
                     /gene="eno"
                     /locus_tag="VXB91_001753"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HEV0471165.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
     gene            2342..2788
                     /locus_tag="VXB91_001754"
     CDS             2342..2788
                     /locus_tag="VXB91_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HEV0471166.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAKPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPFGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            complement(2785..3588)
                     /locus_tag="VXB91_001755"
     CDS             complement(2785..3588)
                     /locus_tag="VXB91_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HEV0471167.1"
                     /translation="MKIVIAPDSFKESLTAQQVAEAIKRGFQQSIADVECLLCPVGDG
                     GEGTVDAIRHSLDLKEKWIQVTDPFGQKEAMRYFQKGELALFEVADLVGLGKIPLEKR
                     NPLQIQTCGIGELILHLISKGIKDIYIGVGGTASNDGGLGIAAGLCAFAQASIVSGID
                     TCLDLINFDKKVSDADLVVVGEGRLDSQSFAGKAPIGVAKRTPVGVPVIAICGSLAED
                     LPPLPFENIQAVFSILEKSEPLEDSLKNASLYLERTAANIGHLLNMCKI"
     gene            complement(3597..3926)
                     /locus_tag="VXB91_001756"
     CDS             complement(3597..3926)
                     /locus_tag="VXB91_001756"
                     /inference="COORDINATES: protein motif:HMM:NF012905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HEV0471168.1"
                     /translation="MERLAKSLGIAYFTANQLEVKEGLLTGKLVGQIISPQVKKETLE
                     KWRKKLKLSKERTVAIGDGVNNLLMLKSAELGIAFCSKEMLKKEIPHHVDKRDFLEVL
                     PLIDCLE"
     gene            complement(3871..4242)
                     /locus_tag="VXB91_001757"
     CDS             complement(3871..4242)
                     /locus_tag="VXB91_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family phosphatase"
                     /protein_id="HEV0471169.1"
                     /translation="MSQVKGLCVLDVDGTLILEEVIDLLGREAGHEAEISQITSRAMR
                     GELVFESSLRKRVSLLEGLPILVFDNVFNSIHLSLNVPEFISILQKNGILVGLVSGGF
                     TPIVGEISKIPWYCLFHCQPA"
     gene            complement(4301..5734)
                     /gene="glgA"
                     /locus_tag="VXB91_001758"
     CDS             complement(4301..5734)
                     /gene="glgA"
                     /locus_tag="VXB91_001758"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HEV0471170.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGNQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYCWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGLERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWFAQIYPDKLSANITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            complement(5731..6870)
                     /gene="glgD"
                     /locus_tag="VXB91_001759"
     CDS             complement(5731..6870)
                     /gene="glgD"
                     /locus_tag="VXB91_001759"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HEV0471171.1"
                     /translation="MKIDKYSAILGNTVGFHDMSTLTDHRPVASLPFGGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTLLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAETFNMSTDIFVVDTPWLIEHLEEEAKKEHPEK
                     LRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVSTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GEGAQVEYAILDKGVEVELGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            complement(6860..8002)
                     /locus_tag="VXB91_001760"
     CDS             complement(6860..8002)
                     /locus_tag="VXB91_001760"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HEV0471172.1"
                     /translation="MKNEMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGINSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEA
                     SRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDF
                     GKNVIPNYLESGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYS
                     RNLISPPNFLGANAHVEDSLVVDGCFVDGTVKHSILSTGAQVREGAEVLDSVIMSGAI
                     IGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVATDED"
     gene            complement(7992..9920)
                     /gene="glgB"
                     /locus_tag="VXB91_001761"
     CDS             complement(7992..9920)
                     /gene="glgB"
                     /locus_tag="VXB91_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HEV0471173.1"
                     /translation="MDNREALKTFMTGENFYLQHYLGAHREELNGEHGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRNDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPF
                     AVRYEARPGTGAILTELREKKWKDGLWLARRKRWGFEERPVNIYEVHAGSWKRNSDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDVYHLDGIRVDAVSNMLYLDYDDAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPDVMMIAEESSSATKITGMKEIGGLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNLEDPMNAKMKYFTSQLNQFYKDH
                     RCLWEIDTSYDGIEIIDADNRDQSVLSFIRKGKKGEMLVCIFNMVPVERKDFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTNKNQKGVENEK"
BASE COUNT         3038 a         2212 c         1773 g         2997 t
ORIGIN      
        1 cgatgacgag cgactttttt gaagcttggt ttcagaaatt tctcttacca acattaaccg
       61 caccattggt tattatatta aaacgaagta agaataggac aaatcgatca ggacagtaaa
      121 atctaattct aacaatgttt tagaagtaga ggtgtactat tctagtttca atctactata
      181 ttaatggaca atgcaagatt ccatagaatg gggaagctag aactcttgtg tgaagagttt
      241 gggcataaac ttttacctct tcctccctac tcgcctgagt acaatcttat tgagaaaaca
      301 tgggctcata tcaaaaagca cctcaaaagg gtattaccaa gttgcaatac cttttatgag
      361 gctcttttgt cttgttcttg tttcaattga ctatataaat tgtctaagcg aaacaaccga
      421 taagaattgg cacaaaagcg accgtatttt tgttaccaat acaggaaaac cagttcatag
      481 ttctatcttg agcaagtctc tccagcgagc aaacgaacgc cttaaaaaac caattcccaa
      541 acatctgtcc cctcacatct tcagacacac cactattagc atcttatcag aaaataaaat
      601 tcctttaaaa acaatcacgg acagggttgg tcattccgac tctgaagtca ctacttccat
      661 ctacacccac gtcacaaaga acatgaaaga tgaagcaatc aatgtactgg ataaagttat
      721 gaaaaagatt ttttaaaaag ttttgtccct tttttgtcct ctaaatacaa aaatagccct
      781 tcggataaaa tccgaggggc tagaaacgtt gttaaatcaa cggccgaact tttgaatttc
      841 atggttcggg ataaaatagt tcactgaact attttatttt ttaaggttgt agaatgattt
      901 caatccacga tattcagcta cttcaccaag ttggtcttcg atacgaagca attggttgta
      961 tttagcgatg cggtctgtac gtgaaagtga accagtcttg atttgtcctg cgttagttgc
     1021 aactgcaata tcagcgattg ttgaatcttc agtttcacct gaacggtgtg atacaacagc
     1081 agtgtaacca gcttctttag ccatttcgat agcttcaaaa gtttcagtaa gagtaccgat
     1141 ttggttaact ttgataagga ttgagttagc agcaccttct tggataccac gtgcaaggta
     1201 gtcagtgttt gttacgaaga agtcgtcacc aacaagttgt actttcttac caagacgttc
     1261 agtaagagct ttccaaccat cccagtcgtt ttcatccata ccatcttcaa tagtgatgat
     1321 tgggtatttg ttaaccaatt cttcaaggta gtcgatttgt tctgcagatg tacgaacagc
     1381 agcaccttca ccttcaaatt tagtgtagtc gtaaacttta cgttctttat cgtagaattc
     1441 tgatgaagca cagtcaaatc cgataaatac gtctttacct ggtacatatc cagcagcttc
     1501 aatcgcagca aggatagttt caacaccatc ttcagttcct tcgaaacgag gagcgaatcc
     1561 accttcgtca cctacggcag tttccaaacc acgtgattta aggattttct taagagcgtg
     1621 gaagatttca gcaccgtaac gaagggcttc tttaaatgtt ggcgcaccaa ctggcaagat
     1681 catgaactct tggaaagcga ttggagcgtc agagtgagaa ccaccgttga tgatgttcat
     1741 cattggagtt ggaagaactt tagtgttgaa tccaccaagg tagctgtaaa gtgggatttc
     1801 aaggtagtca gcagcagcac gagctacagc gatagacaca ccgaggattg cattcgcacc
     1861 caatttacct ttgttaggag taccgtcaag tgcaatcata gcacggtcaa tagcttgttg
     1921 atcacgtaca tcgtagccaa tgatagcttc agcaatgatg ttgtttacgt tgtcaacagc
     1981 tttttgtgta ccaagaccac cgtaacgaga tttgtcaccg tcgcgaagtt caactgcttc
     2041 gtgttcacca gtagaagctc ctgatggaac cataccacgt ccgaaagcac ctgattcagt
     2101 gtaaacttct acttcaagtg ttgggttacc gcgtgagtct aggacttcgc gagcgtaaac
     2161 atcagtaata attgacattt tttactctcc ttatgagtta aattttttac acctctataa
     2221 taccttaaaa cccctccttt ttcaagaaaa aacgttatct ttgtgcaact tttccttaac
     2281 tttataaagt aatcgctttc ttttgtctgt tttattctaa cttttatgat atactgtttt
     2341 catgacagat ttatcaaaac aattacttga aaaagctcat ggtgggttaa aaataaatcc
     2401 ggatgagcaa agacgctatc ttggtacttt tgaggaaaga gttcttggat atgtagatat
     2461 tgacacagca aatagccctc agttagaaaa aggcttttta tttattttag aaaaccttca
     2521 ggaaaaagca aagccactat ttgtgaagat ttcaccaact atcgaatttg ataagcaagt
     2581 tttctactta aaagaagcaa aagaaactga tagtcaagcc accatagtat ctgaagagca
     2641 tattacttct ccttttggcc tggttattca tagcaatgca ccagttcaag tagaagaaaa
     2701 agaccttcga cttgcttttc caaaactttg ggaagttaaa aaggaagaac cagccaaaac
     2761 atccttatgg aagaaatggt ttagctaaat cttgcacata tttaataagt gcccaatatt
     2821 ggcagccgtg cgctccagat agagactggc atttttcaaa ctatcttcta aaggttcact
     2881 tttctccaaa atagaaaaga cagcttggat attttcaaat ggtaggggag gtaaatcttc
     2941 agcaagacta ccgcaaatag caataacagg aactccaaca ggggttcttt ttgcaacacc
     3001 tataggcgct ttcccagcaa agctttgact atcaagtctt ccttctccaa caacaaccaa
     3061 gtcagcatct gaaactttct tatcaaagtt gattaagtcc aagcaggtat caattccaga
     3121 cacgatactt gcctgagcaa aggcacacaa accagcagca atccccagtc ctccatcatt
     3181 actggccgtg ccaccaacac cgatataaat atctttaatc cctttagaaa tgagatggag
     3241 aatcaactct ccaataccac aagtttggat ttgaagtgga tttcgtttct ctagcggaat
     3301 ttttccaaga ccaaccaagt cagctacttc aaatagtgcc agttcccctt tttgaaaata
     3361 gcgcatggct tctttttgtc caaaagggtc tgtcacttgg atccattttt cttttaggtc
     3421 aagagaatgt cggatagcat ctacagtacc ttctccccca tcaccaacag ggcagaggag
     3481 acattctaca tctgctatcg attgttggaa gcctcttttt attgcttcag ctacctgttg
     3541 agctgtcaag ctttccttaa acgaatccgg tgcaattaca atcttcatat tttccctcat
     3601 tctaaacagt caatcaaagg aagaacttct aaaaaatccc tcttgtcaac atgatgtggt
     3661 atttcttttt tgagcatttc tttggaacaa aaggcgattc ctaactccgc cgacttcaac
     3721 attaatagat tattaacccc atcaccgatt gccaccgttc tttctttaga aagttttagt
     3781 ttctttctcc atttttccag agtttctttt ttgacctggg gacttataat ttgtccaact
     3841 aattttcctg ttaaaagacc ttctttgact tcaagctggt tggcagtgaa ataggcaata
     3901 ccaagggatt ttgctaatct ctccaactat tggtgtaaat ccaccagaca ccagaccaac
     3961 taggatgcca ttcttttgga gaatagagat gaactctggg acatttagcg atagatgaat
     4021 tgagttgaag acgttatcaa agaccaaaat aggaagacct tccaacaagg acactctttt
     4081 tcttaaactg ctttcaaaga ccaactctcc tcgcattgct cgacttgtaa tctgcgaaat
     4141 ttccgcctca tgacctgcct ctctccctaa aagatcaatc acttcttcta ggattaaggt
     4201 tccatctaca tccaaaacac acaagccttt tacttgagac atcagttctc ctctctaaac
     4261 agcctaaaaa tcgtatgaag tcatcatacg attttatcta ttaattaact aaactatggt
     4321 acaagtcaag gtatgacttg caggctgtat cccatgagaa gtcactctcc atagcttgtt
     4381 tttgtaggtt tctccaaatg tctggatggt ttctatacaa gtccaatgct gtttggaaag
     4441 tccaatttaa ccaataagga gatagattgt caaagctaaa gccagtaccg cttccttcga
     4501 ttggattgaa agcgcgaact gtatctcgca agcctccaac ttcatggacc aatggcaagg
     4561 ttccataacg catagccatc atttgagaca agccacacgg ttcaaaacga cttggcatga
     4621 ggaagaggtc acaagcagcg tagatttcct gagcaagttt gacatcaaaa gtgatatttg
     4681 ctgatagctt gtctgggtaa atctgagcaa accatgagaa agctccttca aaggctggat
     4741 cgccagttcc caaaagaaca atctgaacat cttcttgcaa gatatggtga agactttcga
     4801 ccaccacatc aaaacctttt tgacgtgtca aacgagaaac aattcccacc agtggaacgt
     4861 ctgctctaac aggcaagcca actctttctt gcaattttgc cttatttttg gctttcccag
     4921 acaaatcttc ctgattgaaa tgatagtcta aaagagcatc cgtctgagga ttataaagat
     4981 cagcatcaat cccattcacg ataccagata ctttaccaga ctccatttta agaatctgat
     5041 ccaaattaca tccaaactga ctagtcataa tttcatgagc atagctaggt gaaacggttg
     5101 aaacacggtt cgcatagaga atacctgcct tcatccagtt cagacagttg ttccatcgaa
     5161 gggtgccatc agcgtaacgt tcaaggccaa ctccaaacaa atcacccaac attccttctg
     5221 aaaattgtcc ttggaattct aaattatgaa tggttaaaac tgtttcaatg tcctcatagg
     5281 cttgaatcca acagtatttt tccttcaaca agaaaggaat catagctgta tggtagtcat
     5341 gaacatggag aagatcagga ataaagtcaa tcctttccat agcctcaatg gcagccagtt
     5401 ggaaaaaggc aaagcgttct ccgtcatcaa aatcaccgta aacatgacca cggaagaaat
     5461 aatattgatt gtcaataaag tagaaggtta caccatttaa tactgttttc ttaattccac
     5521 aatactgtct acgccaacca acgctcacct caaaatgaag cacatcttca atctgatttc
     5581 caaatttagc ctctaccata tcatagtagg gtaaaatcac tgcaacttcg tgcccagctt
     5641 ttaccagtga ttttggaaga gcgccaatga cgtctcccaa accacctgtt tttgaaaagg
     5701 gtgcaccctc tgctgctaca aataaaattt tcatgaatga atatcctctg ttactttagc
     5761 acctttctta accacaactg gatgttctgc agttcctcga atcacaacac caagctcaac
     5821 ttcaacccct ttgtccaaga tagcatattc gacctgagcc ccttctccaa taacaacacg
     5881 agggaagagc aggctatctt taaccaagct atccttatgg acatgaatat tacgtgatag
     5941 aacagaatta gctacttgac cttcaataat actaccagag gcaaactgag aagtgcttac
     6001 cttagatgta ttagcatagt aagttggctc ttcgtttttg acctttgtat aaatcttttg
     6061 gtttggtgag aaaagagaat agaatttttg tgattcaagc atatcgatat tcgcttgata
     6121 ataagattta acagagtgaa tattggctag atagcccgtg tactcgtagg caaaagctcc
     6181 ctcttttaca gccaaatccc gtaaaacata gcgcaatttc tctggatgtt cttttttagc
     6241 ttcttcttcc aagtgttcaa tcaaccaagg tgtatcaacg acaaagatat ctgtagacat
     6301 attgaacgtt tcagctgttg acttgctatc aaagagttta tgagaaagaa catggtctgt
     6361 ttcatctaca tccaagattg catttacttc tgaaatatct ttcttagcta gttttttata
     6421 aactacagtg ataggctctt ttgttgtact atgtaggtgg aaaacttggt tcaaatcaat
     6481 gttaataaga acatcgcagt tgagggcaac cgtttggttt gagccagaac gtttcaaata
     6541 agtaagaagc tgttggtagt attcttttcc aactgtacta ctttctacac gggtattgta
     6601 aattcctaga tagtaatggc taagaagggt tgataagccc cactcgcgcc ctgaacgaat
     6661 atggtcaaag actgagctga tattatcctg ctggaaaata ccaaagacac tacgaacacc
     6721 tgcattagca aggcttgaaa gtgggaagtc aatcaaacga tatttcccac caaatggcaa
     6781 acttgctact ggacggtggt ccgtcaatgt cgacatatcg tgaaaaccaa ctgtatttcc
     6841 taaaatggca gaatatttat caatcttcat ctgttgctac ccccactact tcattatatc
     6901 ctacaacttg tacttcatct gttccatcaa tttcgacacc gtcagaaata atcgcacctt
     6961 caccaataat ggcacgttta atcttagctc cttgaccaat gatagctcca ctcatgataa
     7021 ctgaatcaag gacttccgct ccttcgcgaa cttgcgcgcc tgttgaaagg atagaatgtt
     7081 taacagttcc atcaacgaaa catccgtcta caactaatga gtcttccaca tgagcatttg
     7141 ccccgaggaa gtttggtggt gaaatcaagt ttcttgagta aatcttccat tgacggttac
     7201 gactatccaa ggcattttct ggagaaatat actccatgtt cgcttcccaa agtgactcaa
     7261 tagtaccaac atctttccaa taaccactaa attcataagc ataaacactt tcacctgact
     7321 caaggtaatt tggaatgaca tttttaccaa agtctgacat gccaaccttg ctcttttcag
     7381 cagcgactaa catattacga aggcgttgcc aatcaaaaat gtagattccc atagaagctt
     7441 ttgtagattt aggttgagct ggtttttctt caaattcaac aatacgattg ttagcatctg
     7501 tgttcatgat accaaaacgg cttgcttctt taagagggac gtctaaaact gctactgtca
     7561 agctggcatt attatcctta tgagactgga gcatatcatc atagtccatt ttgtagatgt
     7621 gatccccaga caaaatcaag acatactcag gattgacact gtcgatatag tcgatatttt
     7681 ggtaaatagc gtgactagtc ccctcaaacc aacgatttcc ttcacttgca gaataaggtt
     7741 gaagaataga gacacctgaa ttaataccgt ctagtcccca gcttgaacca ttcccaatat
     7801 ggttgttgag agcaagtggt tgatactgtg taacgacccc aacattatga atccctgagt
     7861 tggcacagtt tgatagggca aagtcaatga tacggtagcg cccaccaaat tgcacagctg
     7921 gttttgcgat gctttgagtg agtttaccga gacgagttcc ttgcccacca gcaagaatca
     7981 aagctaacat ttcatttttc attttctact cctttttggt ttttatttgt gacggtttta
     8041 gtagatttca agcgacgttt gattttccat acacttgctc ccatagccgg tagggtaaag
     8101 gttaaggtct gctcataatc tttccatagt ccttcttgcg tttgaacagt ttgattatgt
     8161 tctttccaaa cgcctcccca ctcttccaac tcagtattcc atacttcttc gtaaattcct
     8221 gcaacgggta gtccgattgt aaaatctttc cgctcaacag gtaccatgtt aaagatacag
     8281 actaacattt ctcccttttt acccttacga ataaaggaaa gaacactctg gtctcgatta
     8341 tccgcatcaa tgatttcaat accatcatag ctggtatcga tttcccacag acagcgatga
     8401 tctttgtaaa actggtttag ctgagaagtg aaatacttca tcttagcatt cattgggtct
     8461 tctaggttag accattccaa ctgttcttca gatttccatt ctaggaattg accgtattcg
     8521 ctacccatga agagcaattt cttaccagga tgacaaattt ggtacgtata gagattgcgc
     8581 aagcctgcga attgattgta acgatctccc cacatcttat gcatcatact cttcttgcca
     8641 tgaaccactt catcgtgcga gaatggcaag agataattct ccttgaaaac atacataaag
     8701 ctgaaagtca ccaggttaaa gtcatattta cgatagatcg gatcttcttc gtagaaacgg
     8761 aggatatcat tcatccagcc catgttccat ttgtagtcaa atcctagacc accaatctct
     8821 ttcattcccg taatcttggt cgcagacgaa ctttcttctg caatcatcat cacatctgga
     8881 tattctaact taataacctc attcaagcgc tgaaggaaat aataaccttc atagttgaga
     8941 tttccgccat ctttattagg tgtccatgga gcatcatcat agtccaaata gagcatgttg
     9001 ctaacagcat ccacacgaat accatccaaa tgatagacat caatccaatg cttaatgcaa
     9061 gaaattaaga aggactggac ttcatttttt ccaaggtcaa aattaagggc accccaacca
     9121 tggttatgag ccttattatg gtcttggtat tcaaaagtcg gtgtcccatc ataataggct
     9181 aaggcatcat cgttgatggt aaagtgacct ggtacccagt ccacaataac cccaatatta
     9241 tgggtatgac actcctcgac aaaatcttga aactcctctg gtcggccata agcatgctct
     9301 aaagcgaagt aacccataag ctgatacccc caactcaagc ccaaaggatg ggacatcaag
     9361 ggcataaact caatatgagt atagttcatt tcaacgagat aaggaatgag ttcatccttg
     9421 agctgggcaa aactataagg actgccatca gaatttcttt tccatgatcc agcgtgaact
     9481 tcataaatat tgacaggacg ctcttcaaag ccccaacgtt ttcttcgtgc cagccaaagt
     9541 ccatccttcc atttcttctc acgaagctct gttaagattg cccctgttcc tggacgagcc
     9601 tcatacctga cagcaaaagg gtcaatcttc atcagttgat gaccattttg acgtgtgaca
     9661 tgatatttgt aaatatgccc ttcttgagcc atattggtaa agacttccca gaccccaaaa
     9721 tcatttctta ccattggaat ctgattttca atccagttgg taaaatcacc aaccaagtga
     9781 acagcctgag cattaggtgc ccaaacacgg aaggtatagc catgctctcc atttagttct
     9841 tccctatgtg ctcctagata atgttggaga taaaaatttt cacccgtcat aaaggttttt
     9901 aatgcttctc tattatccat atactcccct tctcctgtaa gcgttttcta tgtttttatt
     9961 atactacctt tttagagaag attcaagtaa attactatac ttctttaatt attttgaaaa
//
LOCUS       DAVLBE010000065         9758 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.065, whole genome shotgun sequence.
ACCESSION   DAVLBE010000065 DAVLBE010000000
VERSION     DAVLBE010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9758)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9758)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9758
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.065"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(162..1925)
                     /locus_tag="VXB91_001762"
     CDS             complement(162..1925)
                     /locus_tag="VXB91_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HEV0471174.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINFLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFEFMKKLTGAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDKYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPLLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVMTCASFFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMNRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     AQEDPEYTDLLLKKALEFFEF"
     gene            complement(1934..2524)
                     /locus_tag="VXB91_001763"
     CDS             complement(1934..2524)
                     /locus_tag="VXB91_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HEV0471175.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAE
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGGLDLSQLFD"
     gene            complement(2622..3113)
                     /gene="rocS"
                     /locus_tag="VXB91_001764"
     CDS             complement(2622..3113)
                     /gene="rocS"
                     /locus_tag="VXB91_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HEV0471176.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            complement(3190..3882)
                     /locus_tag="VXB91_001765"
     CDS             complement(3190..3882)
                     /locus_tag="VXB91_001765"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HEV0471177.1"
                     /translation="MKIGIIAAMPEELAYLVQHLYNVQEQVVLGNTYHTGTIASHEVV
                     LVESGIGKVMSAMSVAILADHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHTLNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLAFLKALD"
     gene            complement(3899..4213)
                     /locus_tag="VXB91_001766"
     CDS             complement(3899..4213)
                     /locus_tag="VXB91_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="foldase"
                     /protein_id="HEV0471178.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKNHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAVIFLLILLVLAMK
                     LL"
     gene            complement(4225..4770)
                     /locus_tag="VXB91_001767"
     CDS             complement(4225..4770)
                     /locus_tag="VXB91_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV0471179.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTAQRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELQKK"
     gene            complement(4780..6159)
                     /gene="glmU"
                     /locus_tag="VXB91_001768"
     CDS             complement(4780..6159)
                     /gene="glmU"
                     /locus_tag="VXB91_001768"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HEV0471180.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAGQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDVEIAPEVQIEA
                     NVTLKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGDNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPKNQ"
     gene            6303..7103
                     /locus_tag="VXB91_001769"
     CDS             6303..7103
                     /locus_tag="VXB91_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HEV0471181.1"
                     /translation="MRKQIHPLILFSFLGIMMFILIINRPLNDNQSFKTKSNIAQIEA
                     QALKHLDKPIIDLSGWQRPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDK
                     AYKSHITELQKRNVPVAVYAYVAGKSVQEMEKAAEVFYNAASPYSPSYYWLDVEDKTM
                     SNMNEGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSVWIPSYGSDSGFLES
                     SPKTDLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            7198..8040
                     /locus_tag="VXB91_001770"
     CDS             7198..8040
                     /locus_tag="VXB91_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HEV0471182.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDFKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYALNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDFLGTFFPIGIGAGATLIVFSKLMDYALNNYHSR
                     VYHFIIGIVLSSTLLILIPNAGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            8040..8522
                     /locus_tag="VXB91_001771"
     CDS             8040..8522
                     /locus_tag="VXB91_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HEV0471183.1"
                     /translation="MAKKVKIKKTLVEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMIPQKDLEKTTGYIHGANN
                     PVGIRQKHNYPIFIDKIALDLDQMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            8522..9142
                     /locus_tag="VXB91_001772"
     CDS             8522..9142
                     /locus_tag="VXB91_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEV0471184.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPESIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLYTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPAERILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTLNTWNDTSYQS"
     gene            complement(9396..9491)
                     /locus_tag="VXB91_001773"
                     /pseudo
     CDS             complement(9396..9491)
                     /locus_tag="VXB91_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         2981 a         2074 c         1689 g         3014 t
ORIGIN      
        1 agaagttata gtgtagcatt ccaacttcaa agcactataa agtaaattga aacaagaaca
       61 atacaaacaa ttctcgtaaa cggattgcaa ccacaaaaaa gcaagcattc acaagaatac
      121 ttacctatca tgggaggaac aaccgttcct cttttttatt actaaaattc aaagaattcc
      181 aatgcttttt tcaagagcaa atccgtatat tctggatctt cttgggctac ttctatttcc
      241 cgctgaactt tttccaaatc atctgtaatc actccatcta ctcctaagtg aagagatttg
      301 ctgatagctt ctgaatcatt gacagtccag acataaagtt tctgatccgt tgtccatagt
      361 ttgcttacaa aatattcatc caaggttgag tactccatag tatatcctgt cgctcttgtt
      421 ttaggaaaga cagaattgta gggcatgatg aaataaactg gcagttcggc atcatactgt
      481 cttacttttt cgacaacatg gtagtctaaa gactggattt gatgtccata aatcttgagc
      541 tttgcagcat aacgggctaa aaagcggttc atcatgtctg gactatcttt tttactggtt
      601 ttaatttcaa ttagtaattt ttgaccaagt tcgttggctc gactgagata atcttcaaag
      661 cttgaaattt tagtctggta gccattttca aaaatatcaa tccctttaag ctcctccaag
      721 tttaagtctt gaggactttt attgatacct gctagatttt tcaagttagc atcatgcatc
      781 atgacaaact gcccatcttt tgtttcctgc acgtccgtct ccaccaagtc tggtttgagt
      841 tgtgctgtag tttccaagga ctctactgta ttttgaatcc catttgcatt ggaaacccct
      901 cggtgagaaa taagttgagg tagatgaacc atgggagcct ccagataaat ataaccttct
      961 aaggcaaaga aaaaactggc acaagtcatg acaccccatc gcacgatgtg atctttttct
     1021 ctcctaggaa gcatatccag ctcctttcct gtcaaaaatg aaacaaattt aaccaaaaaa
     1081 taagtcagag ccatataata gagattttta atcacgacaa aattcaaaat accaagaatc
     1141 agagactctc tctgagtgat atcatctacc aaagtttgag ccaataataa aggaatcaaa
     1201 ggaagataaa ataataaatg tgctttgagc aagatgtaaa ataaattcca agcataaaaa
     1261 gtaactctct tcttggtttt ctccaagcta aacatcactg cttctcgaac agtcagctga
     1321 tcatatacaa tcttcggaag ggcaaacatc aatctgacag agacatagag aaagataaga
     1381 gatagaagta ggatgctcag ccaccacatc caatatttat cttctaaata agcttggata
     1441 aactctggaa tgacgatttt attaagataa taaatcttca gcattttccg tataaaagga
     1501 aacagcatag ctatatagaa aaagataaac aaggctttag cgccagttag ctttttcata
     1561 aattcaaaac tttcatggaa aaccttgcgg atatactcaa ttagccttcg cttttcatta
     1621 tagaggagat gacgagcacc aataaagagg agtcctattt gaaaataagc aaccagaaag
     1681 ttaattacaa tcaaggctaa aaaagctaga ctaatcaatg gagaatgagt aaggatggct
     1741 aagacattgt tataggaaat aaaaagataa cctgtctgat ctaataagaa gctagccaac
     1801 catgaattga atggtaccca caaatactcc actatcataa aaatcaagaa aaatagaaag
     1861 aggattttat caagattgag gtaaatctgt ttaagaccca attttttagg tttttcaggt
     1921 ttcataggca ctcctagtca aataattgag acaagtccaa gccaccaaaa ggattgtttg
     1981 ataagctact ttctgtctct aacaattccc tagcttgatc cgactctaag aaggattcgt
     2041 aaacacgcgc cgtcatccga gcatcctcta aactattatg agactgacct tgaaatccaa
     2101 gaaatgaggc aacagtttgc aatttgagat tggcaatacc atgtaaatct gaactccgac
     2161 gttcaaaagc ttcatcatac aaatccacct tgtactgttg gctatagtct aaaccatgct
     2221 ctgctaaaat aggtaaatca cttttagcag cattgtagcc tatcatcagc aaagaaccca
     2281 caaactcttg gaattcttct aagactttct caactggagg agcatctttt aaggtctcag
     2341 ctgtaatccc ggtcaaacca ttgataaagc tttttagagg gacgctggta tgaacatagg
     2401 aatcataggc atcgatttcc cgaccatctc taaaacgcac tgccgatact tgaatcaagt
     2461 gtgtttgtcc ttcgtgctga ttaaattcta aatcaaaagc aatgtaatct tctaatcgtt
     2521 ccattctgta cctctcctct actgtctctg ttctaatcaa ctatactatt cacaaacaaa
     2581 agaagccatc aggttagcat ttaacctaaa cagctccttg attatcctcc aaataaacga
     2641 gcaaaaaagc cttttttagt ggattggact tcttcttttg cttggtccag ctctagctta
     2701 agattttctt gatccttcat ggcttgaagg gtcaattgtt gttgctgatc taattgtttg
     2761 tctttctcag caatctgacg gtctttgata cgcatctgct cgtctttttc tgataactga
     2821 cgatccttgg cttttaattg ttcataaaga cgaagaattt ctgcattctt ctcatccact
     2881 agaatctcca tcagttcacg ttgtttgaca tcttcactga caggttcatc ttcaaaaatc
     2941 gtttttttat agatttcttc tagcttaatc aagccacttc tggtaacaac tgttacccct
     3001 ttgtcatttt tatctgtgtc ttcttctggt aattctttga cacggttatt gattgcttgg
     3061 cgagataatc ctaagacctc tgcaatctca ctgacggtca tttcaatact cataatatcc
     3121 tctgaaacgt tttctagctt ttctttactt aaatcttatc ataagctaga aaaactgtca
     3181 aatttccgct taatctaaag ccttcaaaaa ggccaacaag acttgggcag agcgacgtcc
     3241 agcttcgata ataaactcat caaaaaagat gtttgcttca tggttggcat tgtcactcat
     3301 agctcggatg actaagactg ggagattgag ggtatgcgct gcttgagcaa tagctgcccc
     3361 ctccatctcc acggctaaaa cttctgggaa atgggactta atcgcttcta tcttgtcatt
     3421 tcctgcaaca aaactatctc ctgtagcaat caaaccaaga tgccagtttt ggtccaattg
     3481 agataaactc tcttggattt gagcaacaaa ggttttgtct gattcgaaat aaagcggttg
     3541 ttgcgccatt tgtccataag catagccaaa agctgtgaca tccacgtcat gataggctaa
     3601 tttgtcagca atcacgacat ccccaacagc gataccttct gctactgccc cagctgaacc
     3661 cgtattaata agggcatcca cctggaaatg atcagccaaa atcgccacac tcatagcaga
     3721 catgacctta ccaattccac tttctacaag aacgacttca tgagaagcaa tggttcctgt
     3781 atgataggta ttccccaaaa caacttgctc ctggacatta tataaatgct ggaccagata
     3841 agccagttct tctggcatag cagcaataat tcctattttc atttcaattc cttttctatt
     3901 acaaaagttt cattgctaaa acaagcaaaa tcaagagaaa gatgaccgcg aataagattt
     3961 tattcaactt agaattgaag acatttctct tggtattttc aatgcgacgg cttttatgaa
     4021 tagatggttc gacctgaatc ttcaaggttt cctggctaaa accatgattc ttaggattgg
     4081 cataaccaaa acgggaagaa gaggttggta aaatcttagt ctcctcatta tcatctagca
     4141 aaggaggacc tgaaattttt tcgcctctat tagctctttc aatcatttca tccgttaata
     4201 aagatttacc catactgacc tcctctattt tttctgcaac tcccaatact gaacagccat
     4261 aattgtcttg gcatcacaaa tatgacctga ttggattaat tctttcgctt cttctaagct
     4321 cacttcaagg acttccaagg tttcatcctc atcctgcgga cgcggatttt ccacttttgt
     4381 caaatcgctt gctaaatata gttttaactt ctcattacaa aagccaatag ctgaataaaa
     4441 atcgtacaag agttctaatt tccctgtata ggctgtttct tcctctaatt cacgaagggc
     4501 agctgccaca ggggctgtgt tttctcctac ttccaatttt ccggctggaa tttcgtaaga
     4561 gacagcctcg atagctttgc ggtactgctt gaccaagatc agtttttgtt catccgttac
     4621 tgctaaaaca cagacagccc cattgtggaa aatcaaatcc cgttgggcag ttcccttgcc
     4681 ttctggtaat tcaacctgat cttggaccag tttaaatatt ggtccttgat agatttcttt
     4741 tcggctaagc gttttttctt caaactccat gataggctcc tactggttct taggatgatg
     4801 aggaagacgt gttgcatatt cgtctttatt gatctgacga ccgcgaccaa tagcaatagc
     4861 atctgctggc acgtctttag taatagttga accagcacca acgagggaat tgtcaccaag
     4921 ttctactggt gcaataatgg ttgaatttga accaacaaag acattgtctc caatgactgt
     4981 cttgtatttg tttttgccgt cataattgac tgtaatagtt ccagcaccga aattaacgtt
     5041 gcttcccact tcacagtttc cgatataagt caaatgacca gccttggtat tctcaccgat
     5101 tgaagatcct ttcacctcaa caaagttacc aatatgaact tgggcaccca gacttgaatt
     5161 tggacgaatg tgagcataag gaccgactgt cacaccgtct gcaacactac tttcctcaat
     5221 catagaattg gtaatgaccg ctcctgctcc gatagtgctg tccactacat aagtaccgtt
     5281 tgtcaaaaca gtctcagcac caattttcgt ttgccctttc aaggtaacat tggcttcgat
     5341 ttgaacttcc ggagcaatct caacatcaat atcgatataa gttgcttctg gattgacaaa
     5401 gctaacaccg ttgaccatat gtttatgatt gatgcgacga cgcataactg actcagctgt
     5461 cgcaagcgcc acacggtcat ttaccccaag actttcatca aaatctttca aagtataagc
     5521 gccaactttt tcaccagttt cacggaaaat accaatgacg tctgtaatat agtattcgcc
     5581 ttgagcgtta ttggtattga tatttttcaa agcctcaaac aaacgctcgt tgtcaaagac
     5641 gtatgttcca gtgttgattt ccttgatttg cttttcaaaa tctgtagcat ccttctgctc
     5701 aacaatacga agaacctcag cattgtcatt acgaacaatt cgtccatagc caaaaggatt
     5761 atccgtttca gcagtcaaga tagtggccac atttttatga ttgatatgga aatcaatcaa
     5821 gtttttcaag ctttcaccag tgattaaagg agtatctcct gcaatgacca aggtgtgtcc
     5881 tgacaaacct tctaagatag gttctgtcat cataactgca tgaccagttc ccaactgttc
     5941 agattgagtc acaaattctg tctgtccagc caagacctcc tcaaccaatt ctgccttgtg
     6001 tcctacaact gttactgtct tttcaggttg gatagctccc acactacgga aaacatgttc
     6061 caacatagaa atacccgcaa ccttgtgcaa aacttttggc aaatcagatt tcatgcgagt
     6121 ccctttaccc gctgctaaaa taatggcaaa atttgacata atcttctctt ttctgtagaa
     6181 attccctttt attataccat atttcaaatc attccgcact cttgaatgaa aaaatgctct
     6241 aaagtctctt ccttaaccca tttttttgat tttttttgat ttttagggta gaattataag
     6301 atatgagaaa acaaattcat ccacttattt tatttagttt tttggggatt atgatgttca
     6361 ttttaatcat caatcgccca cttaatgaca accaatcgtt taaaacaaaa tccaatatag
     6421 cacagattga agcacaggct ttgaaacact tagacaaacc gattattgac ctctctggct
     6481 ggcagcgtcc tgaagaaatc aactacgatg ccctctcaca aaatatttca ggtgctattg
     6541 ttcgtgttca cagtggtgct caaacgacaa aagaaaatga tgcttcattt atcaatggaa
     6601 tagacaaggc ctataagagt catatcactg aacttcaaaa gcggaatgtc ccagttgctg
     6661 tctacgctta tgtagctgga aaaagtgtcc aagaaatgga aaaggctgcc gaagttttct
     6721 acaatgctgc ctctccttac agccctagtt actattggct tgacgtggaa gacaaaacca
     6781 tgtctaatat gaacgaaggt gtcgaaaact ttcgagcaaa actagcatca ctaggtgcta
     6841 aaaacatcgg catctacgtt ggtgtctact tcatggaaga acacagtatt gatacaggca
     6901 agtttacctc tgtttggatt ccgtcctacg gctcagactc aggatttttg gagagcagtc
     6961 ctaaaactga tttagattat gatattcacc aatacacatc taaaggaaaa attgccggct
     7021 ttgaccacga tttagatatc aacgttatct ctcccttaaa aaataaagaa gaaacctttc
     7081 gaaaactttt tttaaaacct taaaagcatt tgtttatcat ttgctttttc tttttgtgtc
     7141 tgattgtgat acaatatagt aaggattttt tgaaatagaa atagttggag gaaatatatg
     7201 ctctcatggt tagcacgcgt tattaaaggg attgtaattg ctcttggatt tatcctaccg
     7261 ggaatttccg gaggggttct agcagcaatc ttaggaatct atgaacgaat gattggcttt
     7321 ctggcccatc cctttaaaga ctttaaagaa aatgttttgt actttattcc agttgccatc
     7381 ggtatgcttc tgggaatcgg cttattttcc tacccgattg aatacctgct tgaaaattat
     7441 caggtttttg tattatggag ctttgcggga gctattatcg gtacagttcc tagcctcctc
     7501 aaagaatcaa ctcgagaatc tgaccgagac aagattgatt tagcttggtt atggacaacc
     7561 tttatcattt ctggattagg actctatgcc ttaaattttg tcgttggaac cttaagcgcc
     7621 agctttctta acttcgtcct agcaggcgca ctattggccc ttggcgtctt ggttcctggc
     7681 ctcagcccat caaatttact tttgattttg ggactctatg ctcctatgtt gactggtttt
     7741 aaaacttttg atttcttggg aaccttcttt ccgattggaa ttggtgcagg tgcaactctc
     7801 atcgtttttt caaaattgat ggattatgcc ttaaacaact accactcacg tgtctatcat
     7861 ttcatcatcg gtatcgtcct atcaagtacc cttttgatct taattccaaa tgcaggaaac
     7921 gctgaaagta tccaatacac aggactttca cttgtcggtt atgtcatcat cgccttcttc
     7981 tttgcgctgg gaatctggct tggtatttgg atgagtcaat tggaggataa atataaataa
     8041 tggcaaaaaa agttaaaatc aaaaaaacat tggtggaaca aatcctatct aaagcagcta
     8101 tccctcatca ggggattcaa atcaatgccc tagaaggaga gcttcctcaa ggttatgaac
     8161 gagatcagat tttcaaaacc ttggcgcttt tgggagacaa gaccggaccg attatcggaa
     8221 ttgtccctat cactcagcac ttgtctgaaa agaaactagc taaaatttct ggcaataaaa
     8281 aagtgagcat gattccacaa aaggacttag aaaaaacaac tggttacatt catggagcca
     8341 ataatcctgt cggaattcgt cagaaacaca attatcccat ttttatcgat aaaattgctc
     8401 tagatttgga tcaaatgatt gtctctgcag gcgaagtcgg acacagcatt atcgtcgcgc
     8461 cacaagactt ggctagcttt gtaaaggcag actttgtaga tattttggag gacatcaagt
     8521 aatgaaactc tactttgtcc gccacggtcg taccctctgg aaccaagaag gtcgttttca
     8581 aggtgctagt ggtgattctc ctcttcttcc tgaatccatt gaaaccctaa aacgacttgg
     8641 tcagtatctc aaggaaattc cttttgatca gatttattca agtgatttac ctcgagcggt
     8701 caaatctgct gagattatcc aaagtcaact ctataccccc tgttctttag aaatcgttcc
     8761 taatctccgt gaatggcaac ttgggaagtt agaaggtttg aaaattgcaa ccttggaagc
     8821 tatttacccg caacaaatcc aggcttttcg ttcaaatctt gctcaatttg acactcgaat
     8881 gttcggagcc gaatccctct atagtacaac tcaacggacc atccaattta tcaaatcatt
     8941 aaaagatagt ccagctgaac gtattctaat tgtcggacac ggcgccaatc ttactgccag
     9001 tcttcgtact ctcctaggct ataaagaacc acttcttcgt aaagatggcg gtctagcaaa
     9061 tgccagcctg accattatag aaacccatga ttttgaaaca ttcactctca atacttggaa
     9121 tgatacttct tatcaatcat aattatagcc tagccttctg aactagaacc ataggagata
     9181 tagtcagttg aaacaaaaat aagataaaag agcctcgtaa aaaggtattg caacttgcca
     9241 ataccttttt tgatatgaac acgtgtcttc tcaacaggat tgtagagcaa aatgaaataa
     9301 gaactgaata atatgatttg agaatttaaa tcaatttata agaatgtttt agaagcagtt
     9361 atgtactatt ttagattcac ttttctatac taagatgagt agggaggaaa aggtaaaagt
     9421 ttatgcccaa actcttcaca taagaactct agcttaccca ttctatggaa tcttgcatta
     9481 tccattaaaa cttccagact catacccttc taaaatctat tcaaaccacg tcagcttcac
     9541 attatatatg ttggttacct cacaagtttt atctgcaacc tcaaagctgt tctttgagca
     9601 gcctacagct agcttcctag tttaatcttt gcttttcact gagtatcaag ttaaaaaatg
     9661 aggctggtca aaaagtcttt aaaataaaaa aaacgcatat tatcaggtgt taaatgaact
     9721 gcaccccaaa agttagacag aaaaaatcta acttttgg
//
LOCUS       DAVLBE010000066         9474 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.066, whole genome shotgun sequence.
ACCESSION   DAVLBE010000066 DAVLBE010000000
VERSION     DAVLBE010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9474)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9474)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9474
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.066"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(86..1909)
                     /gene="dnaK"
                     /locus_tag="VXB91_001774"
     CDS             complement(86..1909)
                     /gene="dnaK"
                     /locus_tag="VXB91_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HEV0471185.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKTKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            complement(2389..2913)
                     /gene="grpE"
                     /locus_tag="VXB91_001775"
     CDS             complement(2389..2913)
                     /gene="grpE"
                     /locus_tag="VXB91_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HEV0471186.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSELDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LGMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(2940..3974)
                     /gene="hrcA"
                     /locus_tag="VXB91_001776"
     CDS             complement(2940..3974)
                     /gene="hrcA"
                     /locus_tag="VXB91_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HEV0471187.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFDRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVNLLNFANLAAYQFFDQPQKVALEIREGLREDQMQNVRVADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQINVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(4138..4647)
                     /locus_tag="VXB91_001777"
     CDS             complement(4138..4647)
                     /locus_tag="VXB91_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001088691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HEV0471188.1"
                     /translation="MNSRVEFRIFTIVDLDKKEEYLHEMHLKGWRYRTSRFGLFYFEQ
                     GQPDDVIYRIYDSRFLKEHKRELQDFRDRGWELIGAGSCSILRKSSSDLLPEDQVYMS
                     KGLKWEVMRSRLRSCIATFLGGLVVCMSLFREDLSMSFFLIFVLYAFLISYLIHGYFR
                     LKRKYRVDE"
     gene            5255..7588
                     /locus_tag="VXB91_001778"
     CDS             5255..7588
                     /locus_tag="VXB91_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEV0471189.1"
                     /translation="MVEFIKSKKEMSEEDIKANFITPAIVSKGWKNGEHIAYEEYFTD
                     GRIEVRGDKARRKEGKKSDYSLYYQFGTRIAIVEAKDNKHSVRAGLQQAIEYGEILDV
                     PFVYSSNGDGFIEHDRITREERELELDEFPTREELFSRMTKEKGLTYEITEAISTPYY
                     TDAFSMKTPRYYQQIAINRTIETVARGQKRVMFVMATGTGKTFMAFQIIHRLRKAGLA
                     KRVLFLADRNILVDQTMAEDFKPFEKVMTKITPKLLTAPEKLNSFEIYLGLYQQLTGE
                     DGTETHYQKFDKDFFDLIVIDEAHRGSAKENSNWRKIIDYFSSATQIGMTATPKETKN
                     ASNTEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVDGYRPETGKVDTNGQLIED
                     RYYGRKDFDKTIVIDDRTQRVAKFVSDYMKQNNARFDKTIVFCVDIDHAERMRAALVK
                     ENLDLVQEDYRYVMQVTGDNAEGKAQLDNFMDVNSNFPAMVTTSKLLTTGVNAKTCRL
                     IVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFFTIIDFRNVTNLFADPDFDGEPVKVLE
                     TGAKTVSGSTPGFVDEEGDPVEKYIVTDKQVTILNSTVQVLDENGKLITESLTDYTRK
                     NILGSYATLNDFITVWHTADKKKLILDELYKKGVYLDAIRESEGISEQEIDDFDLLLK
                     LAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILLNKYMDKGIGELESIETLKLP
                     EFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA"
     gene            7601..9064
                     /locus_tag="VXB91_001779"
     CDS             7601..9064
                     /locus_tag="VXB91_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEV0471190.1"
                     /translation="MSITSFVKRIQDITRNDAGVNGDAQRIEQMSWLLFLKIYDSREM
                     VWELEEDEYESIIPEELKWRNWAHAQNGERVLTGDELLDFVNNKLFKELKELEITSIM
                     PIRKTIVKSAFEDANNYMKNGVLLRQVINVIDEVDFNSPEDRHSFNDIYEKILKDIQN
                     AGNSGEFYTPRAATDFIAEVLNPKLGESMADLACGTGGFLTSTLNRLSSQRKTSEDTK
                     KYNTAVFGIEKKAFPHLLAVTNLFLHEIDDPKIVHGNTLEKNVREYTDDEKFDIIMMN
                     PPFGGSELETIKNNFPAELRSSETADLFMAVIMYRLKENGRVGVILPDGFLFGEGVKT
                     RLKQKLVDEFNLHTIIRLPHSVFAPYTGIHTNILFFDKTKKTEETWFYRLDMPDGYKN
                     FSKTKPMKSEHFNPVRDWWENREEILEGKFYKSKSFTPSELAELNYNLDQCGFPKEEE
                     EILNPFELIQNYQAERATLNHKIDNVLADILQLLEDK"
     gene            9064..>9474
                     /locus_tag="VXB91_001780"
     CDS             9064..>9474
                     /locus_tag="VXB91_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV0471191.1"
                     /translation="MTPEQLKASILQRAMEGKLVPQNPNDEPASELLKRIKAEKEKLI
                     SEGKIKRDKKETEIFRGDDGKHYGKFADGSTQEIDVPYDIPDTWEWVRIKSIYWNFGQ
                     NKPEKSFRYIDTSSIDRKKNIINYKNLQYLSPEQA"
BASE COUNT         2943 a         1774 c         1863 g         2894 t
ORIGIN      
        1 tgttctatag ttatcagctt gattacaaaa atcattataa acttttcgtg tattttttag
       61 atactcttca tccaatacac tcatcttact tttccgtaaa ctctccgtct acgacgtcat
      121 cgcctgcgtt ccctgttgct tgtgcgcctt ctgctccttc ttgagcttgt tgcgctgctg
      181 cggcttgttc gtagagttta acagcaagtc cttgagcttt ttcgttcaat gcttcaagtt
      241 ttgttttcat gtcgtccaag ttgttgtctt cttgagcttt cttaaggtca tcaagggcag
      301 cttgggcagc gtcacgttct gcgtcgaagc ctttaccttc agtttccttg attgtctttt
      361 cagtcgcaaa gattgcttgg tctacttcat tacgaaggtc tacttcttct ttacgtttct
      421 tatcggcttc agcgtttgct tctgcatctt tcatcatgcg gtcgatttct tcgtcagtca
      481 aacctgagtt cgattggatg acaatagttt gttctttttg agttccaagg tctttggcct
      541 taacagacac gataccgttc ttgtcgatgt caaatgttac ttcgatttga ggaattccac
      601 gaggtgcagc tgggatatca gtcaattgga agcgtccaag agtcttgtta tctgctgcca
      661 ttgggcgttc accttgaaga acgtggatat caacggctgg ttggttgtct gctgctgttg
      721 agaagacttg tgatttagat gttgggattg tagtgttgcg atcgataagt tttgtaaata
      781 ctccacccat tgtttcgata ccaagtgaca atggcgttac atcaagaagg acaacgtcct
      841 tgacatcacc agtaatcaca ccaccttgga tagccgcacc catagcaact acttcatcag
      901 ggtttactga tttgtttggt tctttaccag tttcagcttt aacagcttca acaacggcag
      961 ggatacgagt tgaaccacca acaaggataa cttcgtcgat ttctgacaag ctcaaacctg
     1021 catctgaaag ggcttgacga actggaactt ttgtacgttc aacaaggtca cgagtcaaat
     1081 cgtcaaattt cgcacgagtc aaagtcattt ccaagtgaag aggtccagcc tcacctgcag
     1141 tgataaatgg caagctgatt tgtgttgaag ttacaccaga aaggtctttc ttcgcttttt
     1201 cagccgcatc tttcaaacgt tgcattgcca tcttgtcagt agacaagtcg ataccgtttt
     1261 ctttcttgaa ttctgctacc aagtggtcaa tgattttttg gtcaaagtcg tcaccaccaa
     1321 gtttgttgtc ccctgcagtt gacaatacgt cgaagacacc gtcacccaat tcaaggatag
     1381 agacgtcgaa tgtaccacca ccaaggtcaa ataccaagat tttttcttct ttgtcagtct
     1441 tgtccaaacc ataagcaaga gctgctgcag ttggttcgtt aacaatacgt tctacttcaa
     1501 gaccagcaat tttaccagcg tcttttgttg cttgacgttg agcgtcgttg aagtaagccg
     1561 gaactgtgat aacagctttg gttactttct caccaaggta gtcttcagcg tagcctttca
     1621 agtattgaag gatcatagct gagatttctt gtggagtgta ttcttttcca tttgcagaaa
     1681 ctttttcaga agttcccatc ttagatttga tagagataac tgtatctggg tttgtaactg
     1741 cttgacgttt tgcagcatca ccaacgatga tttctccgtt tttgaatgag actacagatg
     1801 gagttgtgcg gtttccttct gggtttgcga tgattttgct ttcagttcct tcaagaactg
     1861 caactgctga gtttgttgta cctaagtcaa taccgataat tttagacatg tgtttttctc
     1921 cttgttagtt aattttctat ttttcttttt gatactcttc ttaagtggcg acgccgtcag
     1981 agcttgactt cgtcagtctc ttttactaaa ctttgagcct aaggtctcaa aatttgcgca
     2041 aatagcgcca cggcgaagag tatcgtcttt ggttcgcttc gctcactatt acaaagcaaa
     2101 acatatttta tctttcttca tagtttattg tcgtttcgga caagttttct attatgtaaa
     2161 ttgcgacacg aggagtcgaa atcgatttta tttcgacgac gagttagtaa ggaagctagg
     2221 caaacgccat agcaattgcc gttttctgac gagttgcttt agctaccgtc agaattgccg
     2281 aatcgaacac gccctaagct ctgagtaaaa aagatagatt ttcttgtgtt catcgaacac
     2341 ttcgtcaatc tcctattttt actgcgagct ttttacgggc tttgtatctt agttatacac
     2401 cactaccatt gctgggcgta ggatgcggtc atggagtttg tagccttttt gaaagacttg
     2461 ggcgatggta tctactgggt gttcatcgtc tgctgggaga gtttggatgg ccatatggta
     2521 gttatggtca aattcgccat ctgctgcgat ttcttcaatt ccttcttctt tcaaagcgtg
     2581 aatcaagctt tcttgcacca tccccaagcc cttcttcaca tcatctgtca aaccttcaac
     2641 tgcaagtgca cgctcaaggt tgtcaagaga tggtaagatt gcttttgcca agtcctggct
     2701 acgataacgt tgcaagtttt gacgttcttc attggcacgg cgttggatat tttgcatttc
     2761 tgcatgagcg cgaagatatt tgttttcgaa ctcatctgca cgttcatttg ccaagtccaa
     2821 ctcagacttt tcaggagttg tttcttcagc tgtttccaca acttcctctt cttgaacttc
     2881 ttctacttct tcatttttta tatcttgggc catgttcgcc tcctttaatg atttcaatct
     2941 taatgtactt cgtaatgatt actgctgagg tagcggtaaa aatctgtcaa cttcatggtc
     3001 aaaacacggt tgaccacatt gatttgattg attagctgtt ggtaatccag attaactgga
     3061 ccgataatgg ctagaattcc aactccccga taaggaatga ggaacttact actaatcacc
     3121 gctaggtcag ctaaacagga ctcttgaccg tctgcaacac gaacattttg catctgatcc
     3181 tcacgcaacc cctcacgaat ctccaaggcc accttttgcg gttggtcaaa gaactgatag
     3241 gctgctagat tggcaaaatt caagagattg accttgcccg ccatcacaat gttttcgttg
     3301 aacatttcct taaagatgtg ttcaaagaga tcgatgacat tatccgttgt tgtaaagtaa
     3361 cgctggataa tctgcggaat ctccgtccga atcttgtagt gaatatctaa aacggtgtga
     3421 ccgaggaaac gttcctgaat gatgctcttc agtttcagca aatcctcctg caagaagttc
     3481 cttggaatca gaaactgact agtaaccgtt cgcgactcgt ctagggtaaa taccgccaag
     3541 gctgtatgtt gccccaaaac aacgatatca aaggctgtca aacgttgcct gctcggctca
     3601 acatccagtg ccactaccgt acagccactc aggtctgtta gcaagttagc agcctcttgc
     3661 agaatatcct ccaatttgaa gaattcctga tcaaaggctt tgacaatctc atatacctca
     3721 ttttcagcca gtcggtcaaa atccagtgag tgtttcacat agtactgaaa accagcaaca
     3781 cttggcatcc gaccgcttga agtatgagcc ttctcaagca acccttgttt ttctagttcc
     3841 gccatgtcat tacgaatggt tgcactgcta gagttaatag actcttgcaa ggcttttgat
     3901 ccgacaggtt cgtgcgtttt ggtaaagatg tcaataatca gatttaaaat atcctgctga
     3961 cgctctgtaa ccatctcatc actcctctct gtctgatcaa ttagcactca atgcatccaa
     4021 gtgctaactt atgattctat tatacaccct tagaagagaa tgtcaagaca aaaactcaaa
     4081 aaattagcac tcttttataa agagtgctaa aaatcaatct gaagacctag aaccttgcta
     4141 ttcatctact cggtatttcc tttttagtct gaaataacca tgaattagat aagaaatcag
     4201 aaaagcatat aaaacaaaaa taagaaagaa agacatagaa agatcctctc taaacaaact
     4261 catacaaaca acaagaccac ctaagaaagt agctatacag gaacgaagtc tagatcgcat
     4321 aacttcccat ttgagcccct tactcatata gacttgatcc tctggaagta aatcagaaga
     4381 cgatttacga agaatcgaac aagaacctgc tcctatcaat tcccaacctc tatctctaaa
     4441 atcttgcagt tcacgcttat gctctttaag aaatctagaa tcatagatac gatagataac
     4501 atcgtccggt tgaccttgct caaaatagaa caaaccaaaa cgactagttc tatacctcca
     4561 acctttcaaa tgcatctcat gtaaatattc ttctttcttg tccaaatcaa caatggtgaa
     4621 aatccgaaat tctactctgc tattcattgt cttaccccaa aattagaaaa catgcctagc
     4681 gttatttatt agataattct ttccactttt gactcaatct ccaaaaaata taagaaatct
     4741 gaatcgcaaa aactatcaat aaaacccaat ctattatgaa aatcaaaaac acttcccaac
     4801 tgaaagaact acctccagtg acaaactttg agaaaaacgg tagtagagct aaaaagagaa
     4861 gcaaaatagg aagcatccgc attgttaaaa tccttttggc ataaaaaaat ctttatttaa
     4921 actaaaatat tatggcaaaa tttacgccag tttttgaacg gctgatgtag atattttata
     4981 ctttcaaaat gtttaaatgt gattatttat ttttgaaaaa tagctcacca gcccgactga
     5041 aagtgcttat agaatgataa taagtcgcct gccgaaaaca gcgaaaaata gcagtgttat
     5101 gcggagataa tctgacgcga tgcgaaagta tattgcatac ttattttcaa caatttagca
     5161 gagtattttt ataagtgtga tataatagaa gtataatttg ttctgatagt ttattttatg
     5221 gagaagtaga tttttagaat gcggaggatt caatatggtt gagtttataa agtctaagaa
     5281 agaaatgagt gaggaggata ttaaagcaaa tttcatcact cctgctattg tatccaaagg
     5341 atggaaaaat ggtgagcata tcgcttacga agaatacttc actgatggtc gaattgaagt
     5401 tagaggagat aaggctcgtc gtaaagaagg aaaaaaatca gactattcac tgtattacca
     5461 atttggaact cgaattgcaa ttgttgaggc aaaggataat aaacacagcg ttcgagcagg
     5521 attacaacaa gctattgaat atggagagat tttagatgtt ccatttgttt attcttcgaa
     5581 tggtgatggc tttattgaac acgaccgtat cacgagagaa gaacgtgagc tggagttaga
     5641 cgaattccct actcgtgaag aattattttc tcgtatgacg aaggaaaaag gattgacgta
     5701 cgaaattaca gaagctatct caactccata ctatacagac gccttctcaa tgaaaacgcc
     5761 acgctattat cagcaaatag ctatcaaccg tactattgaa acagttgcca gaggacaaaa
     5821 acgagtaatg tttgtgatgg caacaggaac ggggaaaacg ttcatggctt ttcaaattat
     5881 tcatcgcctt cgaaaagctg gtttggctaa acgagtttta ttcttagcgg atagaaacat
     5941 cttagtagac caaacgatgg ctgaagactt taagccattc gaaaaggtaa tgacgaaaat
     6001 tacaccaaaa cttttgactg ctcctgaaaa attaaattct tttgaaattt atctagggct
     6061 ttatcagcaa ctaactggtg aagatggaac tgaaacacat tatcaaaaat ttgataaaga
     6121 cttctttgat ttaatcgtaa ttgatgaagc gcaccgtggt tcagctaagg aaaacagtaa
     6181 ctggcgtaag ataattgatt atttcagttc tgcgacacag attgggatga ccgctactcc
     6241 taaagaaacc aagaatgctt ccaatacgga atactttggt gagccaatct atacttatag
     6301 tttaaaacag ggaatcgagg atggtttttt ggctccatat cgtgttatga gggttaattt
     6361 agatgtggat gtggatggtt atcgtccaga aactggaaaa gttgatacta acggacaatt
     6421 aatagaagat aggtactacg gcaggaaaga ttttgataaa accattgtca ttgatgatag
     6481 aacgcaaaga gttgccaagt ttgtttctga ttatatgaag caaaacaatg cacgatttga
     6541 taaaacaatt gttttttgtg ttgatattga ccatgccgag cgaatgcgtg ctgcacttgt
     6601 aaaagagaat ctagacttag tccaagaaga ctatcgttat gtcatgcaag taactggtga
     6661 caacgctgaa ggaaaagctc aactggataa ctttatggat gtcaattcta attttcccgc
     6721 tatggtaaca acgtctaaat tattaacgac aggagttaat gctaaaacat gtcgtttgat
     6781 tgttttagac tctaatatcc aatccatgac tgaatttaaa caaattattg gtcgtggcac
     6841 acgtctttat cctcaaaagg ggaaagaatt ttttacgatt attgattttc gaaatgttac
     6901 caatttgttt gctgaccctg attttgatgg tgagccagtg aaggtgctgg aaacaggtgc
     6961 gaaaacagtc agtggttcca cgcccggttt cgtagatgag gaaggtgacc cagtagaaaa
     7021 atatatcgtt acagacaagc aggttaccat tcttaattct actgttcaag tattggatga
     7081 aaacgggaaa ctgattaccg aaagcctgac cgactacact cggaagaata tcttaggtag
     7141 ctacgccact ttgaacgatt ttatcacagt ttggcatacg gcggataaaa agaagcttat
     7201 cttagacgaa ctttataaaa aaggagttta tctagatgct attcgagagt cggagggaat
     7261 atcagaacaa gaaatcgatg attttgattt actcctaaaa cttgcctatg gtcaaaaaga
     7321 attaaccaaa acggaacgta tcaataagct caaacaaagc ggatatttat ataaatatag
     7381 tgaggaagcg cgtgctgttt tggaaatttt actgaacaaa tacatggata aaggtattgg
     7441 agaactcgaa agcattgaaa cattaaaact tccagaattt cagatatatg gtggaacctt
     7501 caaaatcatc aatacttatt ttggagataa aaaacgatat ttacaagcaa ttaaagaatt
     7561 ggagcaagag ctatttacag tagcttaatg aaaggaaagt atgtcaatta catcatttgt
     7621 aaaaagaatt caagatatca ctcgaaacga tgctggtgtt aatggtgatg ctcaacgtat
     7681 tgagcaaatg tcttggttat tattcttaaa aatttatgat agccgtgaaa tggtttggga
     7741 attagaagaa gacgagtatg agtcaattat cccagaggaa ttaaaatggc gaaattgggc
     7801 tcatgctcaa aatggggaac gggtattgac aggcgatgaa ttacttgatt ttgtcaataa
     7861 caagttattc aaagagttga aagagcttga aataacttca attatgccta ttcgaaaaac
     7921 gattgttaaa tcagcttttg aagatgcgaa caactatatg aaaaatggcg tcttgttacg
     7981 ccaagtcatc aatgttattg atgaagttga tttcaatagc cctgaagatc gtcattcgtt
     8041 taatgatatt tacgaaaaaa ttcttaaaga tattcaaaat gctgggaact caggagaatt
     8101 ttatacgcca cgtgcagcga ctgattttat tgccgaagtt cttaacccaa aacttggaga
     8161 atcaatggca gaccttgctt gcggaacagg aggcttcttg acttcgactc tgaaccgttt
     8221 aagtagtcaa cgtaaaacta gtgaagatac caaaaaatat aatacagctg tttttggtat
     8281 tgaaaagaaa gcatttcctc atcttttagc agttacaaat ctgtttcttc acgaaattga
     8341 tgaccctaaa attgttcatg gaaatacttt ggagaaaaat gttcgtgaat atacggatga
     8401 tgaaaaattt gacattatta tgatgaatcc accttttgga gggtcagaat tagaaacaat
     8461 aaaaaataac tttccagcag aattacggag ttctgaaaca gctgatttat ttatggctgt
     8521 cattatgtat cgtttgaaag aaaatggtcg tgttggagtt attttacctg atggttttct
     8581 atttggtgaa ggtgtaaaaa ctcgcttgaa acaaaaactg gtagatgagt tcaacttgca
     8641 tacgattatt aggttgcctc atagtgtctt tgcaccgtat acaggaatcc atacgaacat
     8701 tcttttcttt gataaaacaa agaaaacaga agaaacttgg ttttatcgtt tagatatgcc
     8761 agatggttat aaaaatttct cgaaaactaa gccgatgaag tcagaacact tcaatcctgt
     8821 tcgtgactgg tgggaaaatc gtgaagagat tctggaaggt aagttctaca aatctaaatc
     8881 atttacacct agtgaattgg ctgagttgaa ttataattta gaccagtgtg gctttccaaa
     8941 agaggaagag gaaatcttaa atccctttga gttgattcag aattatcaag cggaaagagc
     9001 aactttaaat cataagattg ataatgtatt agctgatatt ttgcagttgt tggaggacaa
     9061 ataatgacac cagaacaact taaagcaagt attctccaaa gagcgatgga agggaaatta
     9121 gtgccgcaaa atcccaatga cgaacctgca agtgaattat taaagagaat taaagctgaa
     9181 aaagaaaaac ttatcagtga aggaaaaatc aaacgagata aaaaggaaac tgagatattt
     9241 cgtggtgatg atgggaaaca ttatgggaag tttgctgatg gaagtactca agaaattgat
     9301 gttccttatg atattcctga tacttgggag tgggtgagga taaaatcaat ttattggaat
     9361 tttgggcaaa ataagccaga gaaatccttt aggtatatag atacgtctag tattgataga
     9421 aaaaagaaca taatcaacta caaaaatcta caatatcttt cacctgaaca agcg
//
LOCUS       DAVLBE010000067         9148 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.067, whole genome shotgun sequence.
ACCESSION   DAVLBE010000067 DAVLBE010000000
VERSION     DAVLBE010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9148)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9148)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9148
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.067"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(44..376)
                     /locus_tag="VXB91_001781"
     CDS             complement(44..376)
                     /locus_tag="VXB91_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HEV0471192.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGAYLSKRACQGICVALAMSSGT
                     FIALAGAAVLTKKLINYIKVGGLGGWLIGAAAGKIAYCIGYGALNRGCDISGNPYPWD
                     GFISATVR"
     gene            complement(432..1334)
                     /locus_tag="VXB91_001782"
     CDS             complement(432..1334)
                     /locus_tag="VXB91_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0471193.1"
                     /translation="MMRKLIVFLLMLPLFVLWLELHVLVNNLLLNLESPLDFVISMSL
                     AFCSLILSKIVLDILYALKDLYKKEALITIFPFIFIGRKKVNVRFSPYFSFHRKSLSP
                     DDLRSRIIWSFILEIAIILVFILKIPFVIIMLTTIFFWTIMDINHLVFNKTEFLFNQN
                     KWEKEDSFESDLTNTLKDKIQKSDLSYSDLMSLQLYDAMNQSTFLTDSELFEDILSKI
                     EDSHNTLLCTGLVELLLYEISISNNNNWQEKVDKIRIQLIRINQLDFFYYTSWLRQNF
                     DFCMNREYHKMKSRKLLLSNKKIV"
     gene            complement(1340..1657)
                     /locus_tag="VXB91_001783"
     CDS             complement(1340..1657)
                     /locus_tag="VXB91_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0471194.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGDWNTFKNNIKGLARASSGFRF
                     AARETGLWAAIWSTRVYSYTYVVSAFAPILGSVAAVNAALAVIGGISVAGITYALWTR
                     KFY"
     gene            complement(1802..3154)
                     /locus_tag="VXB91_001784"
     CDS             complement(1802..3154)
                     /locus_tag="VXB91_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family efflux transporter periplasmic
                     adaptor subunit"
                     /protein_id="HEV0471195.1"
                     /translation="MKLYNKSELRYSRIFFDKRPPAFAFILIISTAIILSGALVGAAY
                     IPKNYIVKANGNSVITGTEFLSAIGSGKVVTLHKSEGDMVNAGDVIISLSSGQEGLQA
                     SSLNKQLEKLRAKEAIFQKFEQSLNEKYNHLSNSGEEQEYYGKVEYYLSQLNSENYNN
                     GTQYSKIQDEYTKLNKITAERNQLDADLQALQNELLQLQQQGDSPSLSDTTSADNKAK
                     LETKISEITTKIEALKTNITSKNSEIDSQQSNIKDMNRTYNDPTSQAYNIYAQLVSEL
                     GTARSNNNKSITELEANLGVATGQDKAHSILAPNEGTLHYLLPLKQGMSIQQGQTIAE
                     VSGKEKGYYVEAFVLASDISRVSKGAKADVAITGVNSQKYGTLKGQVRQIDSGTISQE
                     TKEGNISLYKVMIELETLTLKHGSETVVLQKDMPVEVRIVYDKETYLDWILEMLSFKQ
                     "
     gene            complement(3151..3618)
                     /locus_tag="VXB91_001785"
     CDS             complement(3151..3618)
                     /locus_tag="VXB91_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEV0471196.1"
                     /translation="MAKLEVKDNKKLVLKSVICKKLHDTKVEDVDQEINKFHQHLQLL
                     KAQIFGPLIVKSCGTTIHDDGLITTDFEFYIQAHNAQQYSNIYDVQDSISVPYCLYVR
                     FEDSPEYLQYAYSKLDLYVYENDIQTDGIVYTVYVNSSPEKMVVDIFRPIVSL"
     gene            complement(3611..5830)
                     /locus_tag="VXB91_001786"
     CDS             complement(3611..5830)
                     /locus_tag="VXB91_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001856353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="HEV0471197.1"
                     /translation="MLKKYPCTMQHDQSDCAAAVVSTVLLSYKKELSIMKIREIIGTD
                     MYGTTVSGIVSGLNKLNFTVKAVRVALEDLTPKLTFPAILQVKNDLGQNHFVVLHSIK
                     RNSKFYVADPASGIRKMSSDELGEIYQGITLFMVPNSDFERGKLKGKGLLDLFGRLIF
                     NQKGLISTVILASFVLSIIGILSSLFSKVIMDEVIPYALKNSLYMFLIVFGIVSFLQT
                     LLSAFRQHVLLFLSRKIDIPVLMGYYDHIIHLPYSFFGSRRVGDVLTRFQDAMTIKNV
                     FTSVSISLVMDITLSVISAVVLWTINQSLFLILVFMVIVNIILIYCFKKPYKKINHEQ
                     MEANGLLNSQLIESIRNIDTIKSQHDEEQRLNKIEEKFVHTLEIGYKEGVLQNIQSTI
                     SSMTSTMGGLLFMGVGALFIIDGKMTIGDLLVFQTLSQYFTEPIQNLVGLQLTFQEVQ
                     VAVSRLQELMEVDREDIALDYSIRDFTLCDDIEFKDVTFAYGSRPPVIKDFNLRIKQG
                     EKIAFVGESGAGKSTLVRLLLRFINPSEGKIRIGENDLSDLDYGKLRKKISYIPQTIE
                     LFTGTIIDNLKIGNPSVTYEDMVRVCRIVGIHDTIQRLQNRYGSFVEEGGQNFSGGEK
                     QRLAIARALLSKADLYIFDEATSNLDSFSEQIIQDLIFNKIMDKTTIVVAHRLSTILR
                     CDKICFLENGTIMEYGTHEELMAKNGKYARMVGLQSVQVNQQIQSQAVLDTEEVTYG"
     gene            6296..7159
                     /locus_tag="VXB91_001787"
     CDS             6296..7159
                     /locus_tag="VXB91_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001268160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0471198.1"
                     /translation="MRYDFGKVYKEIRESKGLTQEEVCGGVLSRTSLSKIESGKTTPK
                     YENMEFLLRQINMSFEEFEYICQLYQPSQRTEIMQTYLNMRSIIGTSDLVNLFQKCQD
                     YLKTHHDLPIEEIRDMLEVVIYLRQHGAGELSKHAEQVVKKLWKKIEKQDTWYESDLK
                     ILNTILFSFPIEYLHLITGKILQRLEVYKNYQHLYDLRMTILLNLSTLYLYNQDKNMC
                     KQICYTLLEDAKNKKSYDRLAICYVRIGICRDDAKLIQKGFSLLELTEETSILSHLKK
                     EVEIYYQAKER"
     gene            complement(7448..8839)
                     /gene="argH"
                     /locus_tag="VXB91_001788"
     CDS             complement(7448..8839)
                     /gene="argH"
                     /locus_tag="VXB91_001788"
                     /EC_number="4.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001107608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HEV0471199.1"
                     /translation="MAKNTKLWGGRFEGTVEDWVERFGASISFDQKLAKFDVIGSLAH
                     VQMLGQTGILSLEESEKIQVGLKELLEELEAGQLDFDIANEDIHMNMEVLLTEKIGPL
                     AGKLHTARSRNDQVATDMHLYLKEQLGYVLDKLAHLKGVLLDLAENHVATIMPGYTHL
                     QHAQPISFAYHLMAYYNMFQRDSERFEFNQKHTDLCPLGAAALAGTTFPIDRQLSSDL
                     LEFKQPYTNSLDAVSDRDFILEFLSNASILMMHMSRFCEEMINWCSFEYQFITLSDTF
                     TTGSSIMPQKKNPDMAELIRGKTGRVYGHLFGLLTVMKSLPLAYNKDLQEDKEGMFDT
                     VETILNSLDVLAGMLSSLQVNKEKMQESTEKDFSNATELADYLAGKGLPFREAHEVVG
                     RLVLDSIKSAKNLQDWTLEELQTYHSLITEDIYVYLQPKTAVQRRNSLGGTGFDQVEY
                     QIAVAKKANEAKK"
     gene            complement(8868..9148)
                     /locus_tag="VXB91_001789"
                     /pseudo
     CDS             complement(8868..9148)
                     /locus_tag="VXB91_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031904.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="argininosuccinate synthase"
BASE COUNT         2950 a         1876 c         1342 g         2980 t
ORIGIN      
        1 caacatacga taatatgtat ttttcgaatc ttatctacat tattcatctt actgtcgcag
       61 atataaatcc atcccaagga taagggttcc cgctaatatc acaacctcta ttaagagcac
      121 catatccaat acagtaagct atttttcctg ctgctgcacc aataagccag cctccaagac
      181 ctccaacctt aatatagttt attagttttt tggttaaaac tgcagctcca gctaatgcta
      241 taaaagttcc tgaactcata gctaaagcta cgcaaattcc ttgacaagca cgcttgctta
      301 aataagctcc cccatcaaga tacatcattt cttcttcatc aatcacaaca taattatttg
      361 gtaatacaag ttccatttgt tttctcctcc ttagttgaaa ttgtttcatt tgttttacaa
      421 ataggacgaa cttaaactat ctttttatta ctcagtaata atttccgaga tttcatttta
      481 tgatactctc tattcataca gaaatcaaaa ttttgcctta accaacttgt ataatagaaa
      541 aaatctaatt gatttattct gatgagctgt attctaattt tatcaacctt ttcttgccag
      601 ttgttattgt tactaataga aatctcatac agcagtaact cgacaagacc tgtacacaga
      661 agggtgttat gagaatcttc aattttactc agaatatcct caaaaagttc actatccgtt
      721 aaaaaggtgg attgattcat cgcatcatac agctgaagag acattaagtc agaataactg
      781 agatctgatt tttgtatttt atcctttaac gtatttgtca aatcactttc aaacgaatct
      841 tctttttccc atttattttg attgaaaaga aattccgtct tattaaaaac gagatgattg
      901 atatccatta tagtccaaaa aaatattgta gtaagcataa tgatgacaaa aggaattttt
      961 aaaataaata ctaggataat agcaatttca agaataaaac tccatataat cctagatctt
     1021 aaatcatcag gcgacaaact tttacgatgg aatgaaaaat agggcgagaa cctcacattt
     1081 actttcttcc tgcctataaa aataaaagga aaaatcgtaa taagagcttc tttcttgtac
     1141 aaatctttca atgcgtatag tatgtctaaa actatttttg ataaaatcaa actacagaaa
     1201 gcaagactca tactaatcac aaaatcaagg ggagattcta gattcaatag taagttattc
     1261 actaggacat gcaactctag ccacaagaca aaaagaggga gcattagtaa gaaaacaatt
     1321 agtttacgca ttataacaat tagtaaaatt tacgcgtcca taaagcatac gtaattcctg
     1381 caactgaaat acctccaatt acagccaatg ccgcattaac agctgctact gaccctagta
     1441 ttggagcgaa agcagaaaca acataagtat aagaatacac tcttgtagac catattgcag
     1501 cccataaacc agtttctctt gcggcaaacc taaatcctga ggaagctctc gctaaacctt
     1561 ttatattatt tttaaatgtg ttccagtctc ccccatcaag gtacatcatc tcttcttcat
     1621 caatcacaac ataattattt ggtaatacaa gttccatttg ttttctcctt tttattaagc
     1681 atggttagga tggtttccta acaagtaatc gtcgtctgtg tttctatcac ttagctacct
     1741 agataagata tcctttctct accttatttg tttttatagg ttacctaagg tttaaaacca
     1801 attattgctt gaaacttaac atttctaaaa tccaatcaag ataggtttct ttatcataga
     1861 caatccgcac ttcaactggc atatcctttt ggaggacgac tgtctcactt ccatgtttta
     1921 gagttaaggt ttctaattct atcatgactt tataaagact aatattgcct tctttcgttt
     1981 cttgggaaat tgttcctgaa tcaatctgtc tgacttgtcc ctttagtgtt ccatattttt
     2041 gactatttac accagtaata gcaacatcag cttttgctcc tttcgaaaca cgagaaatat
     2101 cactcgcaag tacaaaagct tctacatagt aacctttttc tttccctgaa acttctgcta
     2161 tcgtttgccc ctgctgaata gacattcctt gtttcaaagg taacagataa tgcagagtac
     2221 cttcatttgg cgctaatata ctatgagctt tatcttgacc tgttgccact ccaagattag
     2281 cctcaagctc tgtaatactt ttattgttgt ttgaacgagc agtacctaac tcactaacta
     2341 attgagcata aatattataa gcctgagaag ttggatcatt ataggtacgg ttcatatcct
     2401 taatattgct ttgttgacta tcaatctcgc tattcttaga agtaatattt gtttttaatg
     2461 cttcgatttt tgttgttatt tctgatatct tagtttctaa cttagctttg ttatcagctg
     2521 atgtcgtatc tgatagagaa ggtgagtctc cttgctgttg aagttgaagc aattcatttt
     2581 gtagagcttg caagtcggca tctaactgat ttctttcagc tgttatttta ttcaacttcg
     2641 tatattcatc ctgaatcttt gaatactggg taccattatt ataattttcc gaatttaact
     2701 gagataggta gtattcaact ttcccataat attcctgttc ttcaccagaa ttagataaat
     2761 gattgtattt ctcatttaat gattgttcaa atttttgaaa gatagcttct tttgcacgta
     2821 acttctccaa ttgtttattt aaagagctcg cttgtaaacc ttcttgccca cttgataacg
     2881 aaataatgac atctccagca tttaccatat ctccttctga cttatgtaaa gtaactacct
     2941 tccctgaacc aattgctgat aggaactctg tacctgttat aactgaattt ccattcgctt
     3001 ttacaatata gtttttgggt atataagctg cgccaaccaa tgcaccgctt aagataatag
     3061 cagttgaaat aatgagaata aacgcaaaag ctggtggtct cttatcaaag aaaatacgag
     3121 aataacgtaa ttctgattta ttatataatt tcataggctt acaattggtc taaaaatatc
     3181 tactaccatt ttttcaggag aagaattaac ataaactgta tagacaatcc catccgtttg
     3241 aatatcattt tcatagacat atagatccaa tttagaatac gcatactgta gatactctgg
     3301 actgtcttca aaacgaacat ataaacaata tggaacagag atagaatcct gtacatcata
     3361 aatgttactg tactgttgag cattatgagc ttgaatataa aactcaaaat cagtcgttat
     3421 taatccatca tcatgaatag tagtaccaca actttttaca attaatggac caaaaatttg
     3481 tgcttttaac aactgcaaat gttgatgaaa tttattaatt tcctgatcta catcttctac
     3541 ttttgtatca tgtaactttt tacagataac tgactttagt accagttttt tattatcttt
     3601 tacctctaac ttagccataa gtaacctcct ctgtatctaa cacagcctgt gactgaattt
     3661 gttgattcac ttgaacgctc tgcaaaccaa ccattctagc atactttcca tttttcgcca
     3721 ttagttcttc atgagtacca tattccataa tagtcccatt ttctaaaaag catatcttat
     3781 cacatcgaag aattgtagac agcctgtggg ctactacaat tgttgtctta tccattattt
     3841 tattaaagat taaatcctga ataatctgtt cactaaatga atctaagtta gaggttgcct
     3901 catcaaatat atacaaatca gctttactca gtagtgctct tgcaatagcc aatcgttgtt
     3961 tctctccacc cgagaaattt tgaccgcctt cttctacaaa ggagccataa cgattttgaa
     4021 gacgttgaat cgtatcatga ataccaacaa tacgacaaac tctcaccata tcctcatatg
     4081 taacagaagg attaccaatt tttagattat caataattgt ccctgtaaag agttctatgg
     4141 tctgaggaat gtaggaaatt ttcttacgta gtttaccata gtcaagatct gataagtcat
     4201 tttctcctat acgaattttc ccctcactcg gatttataaa tcttaataac aaacgaacta
     4261 gcgtactttt tcctgctccg ctttctccaa caaaagctat tttttctcct tgtttaattc
     4321 gcaaattaaa gtccttgata acaggagggc gtgaaccata ggcaaatgtt acatctttaa
     4381 attcaatgtc atcacataag gtgaagtctc taatactata atccaaggca atgtcttcac
     4441 gatctacttc catcaattct tgaagccgac taaccgcaac ctgtacctct tgaaaggtta
     4501 actgcaagcc aactaaattc tgaataggtt ctgtaaaata ttgacttaat gtctgaaaaa
     4561 ccaagaggtc cccaatagtc atttttccat caatgataaa taaggcgccc actcccataa
     4621 ataataaccc acccatggtt gaggtcattg aagatattgt agattgaata ttctgcaaaa
     4681 caccctcttt ataaccaatt tctaaagtat gaacaaattt ttcttcaatt ttgtttaaac
     4741 gttgttcctc atcatgctga gacttaatgg tatcaatgtt acgaatagat tcaattaact
     4801 gtgaattaag aagtccattt gcttccattt gttcatgatt aattttttta taaggctttt
     4861 taaaacagta tataagaatg atgttaacaa taaccataaa aactaatatc agaaataaag
     4921 attgattaat agtccaaagg acaaccgcac taataactga caaggtgata tccatgacta
     4981 atgaaataga gactgacgta aacacattct ttatcgtcat cgcatcttga aatcttgtta
     5041 aaacatcacc aactctacga cttccaaaaa aactataagg aagatgaata atatggtcat
     5101 aatatcccat taaaaccggt atatcaattt ttcgagatag aaacaaaaga acgtgctgac
     5161 gaaatgcaga tagaagagtc tgtaagaacg acactattcc aaatactatc aaaaacatat
     5221 acagactatt ttttaaagca tatggaatca cctcgtccat gataactttt gaaaagagac
     5281 tcgataaaat accaatgata cttaaaacaa aggaagctaa tatgactgta ctaatcaatc
     5341 ctttttgatt aaaaattaac cttccaaata aatcaagaag tccttttccc tttagtttcc
     5401 ctctttcaaa atccgaattt ggaaccataa aaagagtaat accttgataa atttctccca
     5461 gttcgtcact tgacatcttg cgtatgccac tagcagggtc tgctacgtag aacttactat
     5521 tccttttgat actatgtagt accacaaaat gattttgacc taaatcattc ttaacttgaa
     5581 gaatcgcagg aaatgttaat tttggagtca aatcttccag tgctactcga acagctttta
     5641 ctgtaaaatt caacttattc agacctgaaa caataccact gacagtcgtt ccatacatgt
     5701 ctgtaccaat aatttcccta atcttcatga ttgatagttc ctttttgtaa gataaaagaa
     5761 ctgttgaaac aactgccgca gcacaatctg actggtcatg ttgcatcgta caaggatatt
     5821 tttttaacat agaaatactc aattctttag aattaatcta acttttcttt gatgtcaccc
     5881 aaacctcaat cactgcccag tagttcttga attaatttat tttcaaccgt atcattcttt
     5941 gttcttgata tctttccaag cattgtagta cagcagattt ttgcccaagg actgagcctc
     6001 ctttaacaac tcaaactccc ttacattata tcggccagcc ccatggaaag attatagcca
     6061 gactaatcaa tgatataata catactagaa tacaaaatat ttttttattc atactttttc
     6121 tcctatcttt attttctacc tacatagtac ctcttattaa gctcatttta aaattacgtt
     6181 aacttttttc acaaatttat ttcgactttc ttttttactt tttacattgc tatgatacaa
     6241 tatttttaac aaaattttat tgtttgttaa cttttttcac gaaaaggaga aaatcatgcg
     6301 ttatgatttc ggaaaggtct ataaagaaat acgtgagtca aaggggctga cccaagaaga
     6361 ggtctgtggg ggtgttctct caagaaccag cttatcaaaa atcgaaagtg gcaagacaac
     6421 cccaaaatat gaaaatatgg aatttcttct ccgtcaaatc aatatgagtt ttgaagagtt
     6481 tgaatatatc tgtcaacttt atcaaccaag tcaacgcaca gagattatgc aaacctatct
     6541 caatatgcgt tccattatcg ggaccagcga tcttgtcaat ttatttcaaa aatgccaaga
     6601 ctacctcaag acccaccacg atctccctat agaagaaatc agagatatgc ttgaagttgt
     6661 tatttatctc cgtcaacacg gggcagggga actatcaaaa cacgcagaac aggttgtcaa
     6721 aaaactttgg aaaaaaattg aaaaacaaga tacatggtat gagagtgatc taaaaatcct
     6781 caataccatt cttttcagtt ttcccattga atacctccat ctcatcactg gaaaaatatt
     6841 gcaacgccta gaagtctata aaaactatca acatttatat gacttgcgaa tgacaattct
     6901 attaaacctt tccacactct atctatacaa tcaagataaa aacatgtgta agcaaatctg
     6961 ctacacttta ctggaggacg ccaagaataa gaaaagctac gataggctgg ctatctgcta
     7021 tgtccgtatt gggatttgta gggatgatgc gaaacttatc caaaaagggt tctcccttct
     7081 ggagctaacc gaggaaactt ctatactgtc tcatctcaaa aaagaagtag agatctatta
     7141 ccaagcgaag gaaagataaa aaagccgagg gatttcctcg actctttaca tattatttgt
     7201 tcgttagttc ttaataccag ccattgttaa accagaagtt tttagctctg ccaagccaca
     7261 tagtgtgttt actactatgt gtccatgtca ccatgaatcg ccgaacgatt taacgagaaa
     7321 gtatgacttt tacgtttatc ccaactcaat tatgacattt ttttcaaaag tcaatatatc
     7381 tcactttttc aacgacaaga aagaggctgc caatcgacca acctcttatt ctgaacccat
     7441 cactccatca ctttttagct tcattcgctt tcttagcgac tgcaatctgg tattcgactt
     7501 ggtcaaaccc tgtgcctccc aaggaatttc gtctttgaac agcagtttta ggttgcaagt
     7561 agacatagat atcctcggta atgagagaat gataggtttg taattcctcc aaagtccaat
     7621 cttgaagatt tttagcagac ttgatagagt ctagcactaa tcttcccaca acctcatgag
     7681 cttctctaaa tggcaagcct ttccctgcca aataatctgc caactcagtt gcatttgaaa
     7741 agtccttctc tgttgattct tgcatttttt ccttgtttac ctgcaaacta gataacatac
     7801 ctgccaacac atcgagggaa tttaaaatcg tttcgaccgt atcaaacatt ccttccttat
     7861 cttcttgcaa atccttatta taagctaaag gcaaggactt catgactgtc aacagtccaa
     7921 acaaatgccc ataaactctg ccagtctttc ctcgaatcaa ctcagccata tctggatttt
     7981 tcttttgggg cataatagag gaacctgttg taaacgtatc tgacaaggta atgaattggt
     8041 actcaaaact acaccaattg atcatttctt cgcaaaaacg actcatatgc atcatgagta
     8101 tgctggcatt tgatagaaat tctaagataa aatcgcggtc actaacagca tccaaagaat
     8161 ttgtataagg ttgcttaaac tccagcaaat cgctagacaa ttggcgatca atggggaaag
     8221 tcgttcctgc caaagctgcc gcacctaaag ggcataggtc tgtatgcttc tggttaaatt
     8281 caaaacgttc actgtctctt tgaaacatat tgtagtaagc catcaggtgg taggcaaaac
     8341 taataggctg ggcatgttgc agatgggtat agcccggcat gatcgtcgcc acatgatttt
     8401 ccgccaagtc taataaaaca cccttaagat gagccagttt atctaggaca tagcctagtt
     8461 gttccttgag atacaagtgc atatctgtcg caacttggtc atttcgagaa cgagccgtat
     8521 gtaacttccc tgcaagggga ccaatttttt ctgtcagcaa cacttccata ttcatatgaa
     8581 tatcttcgtt tgcgatatca aagtcaagtt gacctgcctc tagctcttct aaaagctctt
     8641 tcaagcctac ttgaatcttt tctgactcct ccaaactcaa aatgcccgtc tgacccaaca
     8701 tctgaacgtg ggctaaagaa ccaatcacat caaatttagc taatttctgg tcaaaagata
     8761 tactcgcacc aaagcgctct acccagtctt cgacagtacc ttcaaagcga ccaccccata
     8821 attttgtatt cttagccata tcacatccac ctctctatcc aatcgtccta tttggcgctt
     8881 ttttgaacct cagaatgaac cttggttgga agtccccata actcaataaa gccaacagcc
     8941 gcatcttggt caaaggtatc tgcactagta tacgtcgcca aattttcatc gtaaagagaa
     9001 tttggtgatt tccgagccac gacctgagcg ctccccctta tacagtttga cttttgcagt
     9061 cccattgaca actttttgag tctctttaat ataagcaatc aaggcttgtg tagccgaact
     9121 aaaccacaaa gcattataaa tgagattt
//
LOCUS       DAVLBE010000068         8961 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.068, whole genome shotgun sequence.
ACCESSION   DAVLBE010000068 DAVLBE010000000
VERSION     DAVLBE010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8961)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8961)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8961
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.068"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            <1..620
                     /locus_tag="VXB91_001790"
     CDS             <1..620
                     /locus_tag="VXB91_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEV0471200.1"
                     /translation="QGLMKVLNLQAKMRQKRKYSSHKGDVGKKAENLIQGQFEGSKTM
                     EQCYTDVTEFAIPASTQKLYLSPVLDGFNSEIIAYNLSTSPNLEQVQTMLEQAFTEKH
                     YENTILHSDQGWQYQHDSYHQFLEGKGIQASMSRKGNSQDNGMMESFFGILKSEMFYG
                     YEKSFQSLKQLEQAIVDYIDYYNNKRIKVKLKGLSPVQYRTKSFG"
     gene            complement(748..951)
                     /locus_tag="VXB91_001791"
     CDS             complement(748..951)
                     /locus_tag="VXB91_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0471201.1"
                     /translation="MIKLYSPYAFLSKYLGAILLSFFCYYAKEIGCNNLTLSVWNDNE
                     GALRFYQRQGMKPQETTMEMIID"
     gene            complement(944..2026)
                     /locus_tag="VXB91_001792"
     CDS             complement(944..2026)
                     /locus_tag="VXB91_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEV0471202.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTVFETAEFDNLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            complement(2152..2934)
                     /locus_tag="VXB91_001793"
     CDS             complement(2152..2934)
                     /locus_tag="VXB91_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HEV0471203.1"
                     /translation="MVYTSLSSKDSNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            complement(2934..4277)
                     /locus_tag="VXB91_001794"
     CDS             complement(2934..4277)
                     /locus_tag="VXB91_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HEV0471204.1"
                     /translation="MNLKTTLGLLAGRSSHFVLSRLGRGSTLPGKVALQFDKDILQSL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILDAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGAYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGADSQLIKQGFDKSRAVFGRQETFHIGDKECTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
     gene            complement(4376..5692)
                     /locus_tag="VXB91_001795"
     CDS             complement(4376..5692)
                     /locus_tag="VXB91_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HEV0471205.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYATVAGTGVDIFDAEAHFLS
                     NKVIEIQAGDEKKELTAETIVINTGAVSNVLPIPGLATSKNIFDSTGIQSLDKLPEKL
                     GILGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYMEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDVNGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            5885..7111
                     /locus_tag="VXB91_001796"
     CDS             5885..7111
                     /locus_tag="VXB91_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HEV0471206.1"
                     /translation="MKSNRYIIAFAGVILHLMLGSTYAWSVYRNPIIEKTGWDQASVA
                     FAFSLAIFCLGLSAAFMGRLVEKFGPKVMGSLSAFLYAGGNILTGFAIDRQELWLLYL
                     AYGILGGLGLGAGYITPVSTIIKWFPDKRGLATGLAIMGFGFASLLTSPIAQHLIAGV
                     GIVETFYILGASYFIIMLLASQFIKRPNEQELAILSSSGKEKTASLTQGMAANQALKS
                     NRFYMLWIIFFINIACGLGLISAASPMAQEMAGLSTSHAAVMVGVLGIFNGFGRLLWA
                     SLSDYIGRPLTFSILLLVNLFFSLSLWLFTDSVLFVVAMSILMTCYGAGFSLIPAYLS
                     DIFGTKELAALHGYILTAWAMAGLAGPILLAETYKMAHSYTQTLFVFLILYSIALALS
                     YYLGRSIKKESQKPLT"
     gene            7310..8884
                     /locus_tag="VXB91_001797"
     CDS             7310..8884
                     /locus_tag="VXB91_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV0471207.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRIEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQDIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVAPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNT
                     LSEKQTGFVIRNKGDK"
BASE COUNT         2590 a         1733 c         1981 g         2657 t
ORIGIN      
        1 ttcaaggctt gatgaaagta ctcaatttac aagctaaaat gcgacagaaa cgaaaatatt
       61 cttctcataa aggagacgtt ggtaagaaag cagagaatct cattcaaggc caatttgaag
      121 gctctaaaac aatggaacag tgctacacag atgtgactga atttgccatt ccagcaagta
      181 ctcaaaagct ttacttatca ccagttttag atggctttaa tagcgaaatt atcgcctata
      241 atctttcaac ttcacccaac ttagaacaag tacaaacaat gttggaacag gcattcacag
      301 agaagcacta cgagaatacg attctccata gtgaccaagg ctggcaatat caacacgatt
      361 cttatcatca gtttcttgag ggtaagggaa ttcaagcatc catgtcacgc aagggaaaca
      421 gccaagacaa cggtatgatg gagtccttct ttgggattct gaaatcggaa atgttttacg
      481 gttatgagaa gtcgtttcag tcgcttaagc aattggaaca agctattgta gactatattg
      541 attactacaa caataaacga attaaggtaa aactaaaagg acttagtcct gtgcaataca
      601 gaactaaatc cttcggataa attaattgtc taactgtttg ggggcagtac attttaacac
      661 ttgatactat gcgttttatt gtgggaagat tttcctcatt ttctagtgaa attgaacttt
      721 ttctaacatc ttttgataga tgacttctta atcaattatc atttccattg ttgtttcttg
      781 gggtttcatc ccttgtcttt gataaaagcg gagagcaccc tcgttatcat tccagacact
      841 tagggttaga ttattgcagc caatttcttt agcataatag cagaaaaatg acaataaaat
      901 agcccctaga tattttgaaa ggaaagcata ggggctatat agtttaatca aaataaagca
      961 aatctttgct ggtgcttgta aagaggtcga agccatcctt ggtaacaaca ccgcagtctt
     1021 caatacgaac accgacttta ccagggatat agatacctgg ttcaacagag aagcacatgc
     1081 cttcttcgat gaccatgtcg tttccttcca tgatagatgg gaattcatgg acatccatac
     1141 cgataccatg cccgagacgg tggttgaagt actcaccata accagctttt tcgatgacct
     1201 cacgggcagc gcggtccact tcatgagcag tcacacctgg cttgataaag tcaagagcag
     1261 cttgttgggc ttcaagagtc aagttgtaaa tatctttctt gaattggtct ggtttgccga
     1321 cagcgactgt acgagtcata tctgacgcat agccattgac cagaacaccc aggtcaaaga
     1381 ggagaagagc atcattttca accttattag ctgctggaat gccgtgtgga ttcgcagcat
     1441 tatcaccagt caagaccatg gtatcaaagc tcatttcata accttcacgt ttcatggcaa
     1501 agtcgatttg tgcgatgata tctgtctcag tcttatcaag agaaatattg tcaaaaccaa
     1561 catgaacagc cttgtcagca taaagacctg caaccatcat tttttgcact tcatcagctg
     1621 atttgatgag gcgcatgcgt tggatacgag gagtgaggtt gtcaaactca gcagtctcaa
     1681 aaactgtttt caaaccatgg tatttggtca agatgagatt gtcaaactca acagcgacac
     1741 gtttgaagtc aagttgtgga agagcatgtt tgattttttg ccatggattt tcagaatcga
     1801 catagcccac tactgggaag gaaacggtgc tacttgcacg ttctacttca agagctggga
     1861 caaagaggag aggttcctga tccgctagga caaagaggaa catttggcgt tcatggggat
     1921 cactgtaaaa accagtgagg taattgattg tgacggggtc agatacgaca gcgacgtcta
     1981 gtttttctga ttcaagatat gttaggattt gttgtaattt agacatatgc taccttcttt
     2041 ctacccctct attttggcaa aaaatgagag aaaatgcaag ggagaagggt aaaagaaaag
     2101 acaaaaaact ccgacaagat aacggagttc tttgatatca ttttcctttg tttaagaaaa
     2161 gtcagccttg cttttgacgt cactgtactc ttcagcgatt tcttggctga gaatgtcctc
     2221 ataggcaggg agttggatgt cctgaccata tttcttcttg agggcagtag taactaggcg
     2281 ataagccaga ttggcattac gagagaggat aggcccgtgg aagtaggaac caaagacatt
     2341 cttataatga accccttcac cgaccttttc ttcgttgttt ccatttccat agacaacctg
     2401 tcccagcggt ttttggtcat cagagaggaa ggtacgacct tggtgatttt caaatccata
     2461 gtaggtttca tcgaaatctt cattgtgaat cttgatgtca ccgataaaac ggttattggt
     2521 ctggttgagc gtgtagtgtc ccatgacccc tagcccttcg atacgttttc ctgaagcttc
     2581 aacataatat tgacccaata gttggaaacc accgcagata gccagaacta caccgtcgtt
     2641 ttggatgtag ttgtcaatgc tctctttttt agcaggtagg tcgtctgcaa tgatactttg
     2701 ttcaaagtct tgaccaccac cgaaaaaggc gatgtcgtag tgattttcat caaagtcatc
     2761 atggagagaa acgatgtcaa cggtcacatg ggctcccagt ttttcagcca catacttgag
     2821 catgaggatg tttccattgt ccccgtaggt attcatgaga tttccgtaga ggtgggcaat
     2881 gttgagctga taggggtaat tgctatcttt tgaggaaagt gaagtataaa ccattagttc
     2941 atctcctttc taacaatctg acgactagcc agcagttcac gaaattccag catggcagta
     3001 taagttgcca gaatataggc atgcttgcag tcttgattct caatggtctt gagaacttgc
     3061 tccagattac tcgtttcagt gattttctca gctggatagc cagtcactcg gaggcgacga
     3121 gcgatttcag aatgacgaac accgccagcg ttgatttcag gaatgtccat gtcagtgatt
     3181 tgctcaaagt ctgcatccca gatccagcta gtgtcaattc catctgcata gttggcatta
     3241 aggaggacag ataggctaaa tggataaggt gctagtttga tcatttcgat agcttgggtt
     3301 gcaccgactg gatttttaat caagacaagg gtacattcct tgtcaccgat atgaaaggtt
     3361 tcttggcgtc caaagacagc acggctcttg tcaaatccct gtttgatgag ttgggaatct
     3421 gcgccgagga aacgggcgat ggccacagca gctagggcgt tatagatatt atagagcccg
     3481 ccgatttgga taccgtattc ttggccgtct atgacaaagc gagagcgatt gttggtcaac
     3541 tcaaccagtt ttgtcaaacg atagtcgaga tcaggacgtt tacatccaca accttcacag
     3601 atataggcac ccaagtttgc ataggtatta tgctcatatt tgaggatgcc ttggcagtca
     3661 ggacagagaa tcccttcggt attgtagtga gcaagttggg ctggtccttt ttccaagtca
     3721 aaaccaaaat actctatagg gtttggaata gttggcttgt agaaaagtgg actgtctccg
     3781 ttaaggagaa cagtagcagt tggaactttt cgaatggcat ccaatatcat gttataggta
     3841 gtatagattt caccgaaacg gtccatctgg tcacggaaga tattagtaat gacaaaaaga
     3901 ctaggctgga tatagtcaca gatacgagat agactggctt cgtcaatttc gaggacggca
     3961 atatttttcc cagtttttga agatttggct gttaggaagg ttgttgcaat ccctgtaatc
     4021 atgttggcac cgcttgggtt ggttagaact tgaccataaa cctcttttaa aatgccgaca
     4081 gtgagggcag ttgtcagggt ttttccattt gttccagtga caacgacaat ctcgtagttc
     4141 ttagctaggc tttgtaaaat atctttatca aattgaaggg cgactttccc tgggagcgta
     4201 cttccacgtc caagacggct taaaacgaag tgggaagaac gcccagcaag aaggcccaaa
     4261 gtagttttta agttcatgtt tctattatat cacaaaagag ggaaaagaca gatttggtgt
     4321 ttcgtagaag taaaaacagc ccaaagaggg ctgtcagtta agatgagatt tcaacttaaa
     4381 tcgcaaacaa gtcattcaag ttctcagcca aggttgggtg agtgaagatt tgttttgtga
     4441 agtaagtgta aggaatcttg ttgtccatag caacagtaat gatgttgatg atttcttgag
     4501 aaccttctga gaagatgctt gcaccaagaa tttcttttgt ttcagtatta acaacagctt
     4561 tgaaagctcc gcgaaggtct ccatttacgt gaccacgagg catggctgca acagggattt
     4621 ctttcactgc gtatggaagt ttcaaatcag ctgcttggct ttcagtcaaa ccaacttgtg
     4681 aaagtgcagg tgtgatgaac atagtatttg gcacattgag acggtcctca agtgtgtagc
     4741 tgccatctcc agcaaggtag ctgtaaacaa cacggaagtc atcaagtgaa atgtaagtaa
     4801 attgaaggcc accgttgaca tctccaactg caaagacacc aggaacgttt gtttgacagt
     4861 gtttgtctac tttaatagca ccacgttcag ttagttcaat atctgtattt tcaagttgaa
     4921 gtggttctac atttggtttg cgtccagttg cgtagagaag ggcgtcgaaa cggtaagttt
     4981 cgtcttcagt tacgacaagc acttggtcac catcgttttt gatttcagta gtatggatat
     5041 tttgaagcaa ttcaatgcca tcttcttcca tgtattgttt agcaagagct gcgatggaag
     5101 gttctgcacg aggtaggaat gtatccaagg catctaggac tgtgaccttg cttccaagtt
     5161 tgttgtaaag gccggcaaat tcaagaccga tatttccgcc accaaggatt ccaagttttt
     5221 caggtaattt gtccaagctt tggatacctg ttgagtcaaa gatgtttttg cttgtagcaa
     5281 gtccaggaat tggcaagacg tttgaaacag caccagtgtt gatgacgatt gtttcagcag
     5341 tcagttcttt cttttcatca ccagcttgga tttcgatgac tttatttgaa aggaagtgag
     5401 cttccgcatc aaagatatct acgcctgtac cagcaacagt cgcatagttt ttaccgttga
     5461 ggcgaccagt gatcgtgttt ttagtagcaa tcacttcttc aaaagacaag tccttttcag
     5521 cagcaactag caaggtttta gttgggatac aaccaatgtt gatacaagtt ccaccgtaca
     5581 tagccttgct gcgttcaacg agggcaactt ttttgccagc tgaagccaat ttacctgcta
     5641 gtgttttacc agctttacca aatccaataa caattaaatc gtatgttaac atttatcttc
     5701 ctcctattcg aatttcattc tagcacaaga aaaaaacttt tgcacaattc tgctacggaa
     5761 aagacagaaa aagataaaaa cgctttccag acaaaaaact agtaattttt tgacaagctt
     5821 gataaactaa aatcctatct atttttatat aagaaagaat aaatgttcga aaataggagg
     5881 ttttatgaaa tcgaatcgtt atattattgc ctttgctggg gtcattttac acttaatgct
     5941 gggttcgact tatgcttgga gtgtttatcg taaccctatt attgaaaaaa cgggatggga
     6001 tcaggcttct gttgccttcg cctttagtct agcaatcttt tgtttgggct tatcggctgc
     6061 atttatgggg cgtttggtag aaaaatttgg tccgaaagtc atggggagtc tatctgcttt
     6121 tctatacgca ggtggaaata tcttaacagg atttgcaata gaccgtcagg aactgtggtt
     6181 gttgtatcta gcttatggca ttttaggtgg gcttggtttg ggagcaggct atattacccc
     6241 tgtgtcaacg attataaaat ggtttcctga taaacgtggt ctcgcaacag gtttagcgat
     6301 tatggggttt ggttttgctt ctttattgac tagtcccata gcgcaacacc tcatcgcagg
     6361 ggtagggatt gtagaaactt tttatatttt aggagcaagt tactttatta tcatgctcct
     6421 agcttcacaa ttcattaagc gtccaaatga gcaagagctt gcaattttat cttcttcagg
     6481 gaaagaaaaa acagcctctt tgacgcaagg aatggctgca aatcaggctc taaaaagcaa
     6541 tcggttttat atgctttgga ttattttctt tatcaacata gcttgtggtt taggcttaat
     6601 ttcagcggca tcgccaatgg cacaggagat ggctggcttg tctacaagtc atgcagcagt
     6661 aatggtgggt gttttgggga ttttcaatgg atttggtcgc ttgctctggg cgagtttgtc
     6721 tgactatatc ggtcgccctc taacctttag tatattactg cttgtcaatc ttttcttttc
     6781 tctctcactt tggctcttta cagattccgt tttatttgta gttgctatgt ctattttgat
     6841 gacttgctat ggagctggtt tttctttgat tccagcttat ctcagtgata tttttggaac
     6901 caaggaattg gccgctctgc atggttatat tttaacagct tgggcaatgg ctggtttagc
     6961 gggacctatt ttattagcag agacttataa aatggctcat tcgtacacac aaaccttgtt
     7021 cgtttttctc attttataca gtatcgcctt ggctttgtct tattatctag gtcgttcaat
     7081 caaaaaagaa agtcaaaaac cgcttacatg attttctgta gaaatggggc tatcttttgc
     7141 tctggtcttg tgttatacta gataggttgc aaagaaaaca gtacttttct tttgtggaaa
     7201 agaagcaaca cgattttata tctagttata tgaaaatacg tcataaaaag aaaagtataa
     7261 actaagccct atagggtggc ttcgcaccac ctttagaaag aagaataacg tgaaatttaa
     7321 tgaattaaac ttgtctgctg atttgctagc agaaattgaa aaagctggtt ttgtagaagc
     7381 tagtcctatc caagaacaaa ctattccttt ggcccttgaa ggcaaggatg ttatcggtca
     7441 agctcagact ggtacaggaa aaactgcagc ctttggcttg cctacccttg aaaaaatccg
     7501 tatagaagaa gcgactattc aagccttggt catcgctcca actcgtgaac tagctgtcca
     7561 aagtcaagaa gaactcttcc gctttggtcg tagtaaggga gtcaaagtcc gttcagtata
     7621 tggcggatca agcattgaaa aacaaattaa ggctcttaaa tctggtgccc atatcgtggt
     7681 gggaactcca ggtcgcctct tggacttgat taaacgcaag gccttgaaat tacaagacat
     7741 tgaaaccctt atccttgacg aagcggatga aatgcttaac atgggcttcc ttgaagacat
     7801 cgaagccatt atttcccgtg tacctgagaa ccgtcaaact ttgcttttct cagcaactat
     7861 gccagatgcc atcaaacgta tcggtgttca gtttatgaaa gcccctgaac atgtcaagat
     7921 tgcggctaag gaattgacaa cagaattggt tgaccagtac tatatccgtg ttaaggaaca
     7981 agaaaaattt gacaccatga ctcgtctcat ggatgtggca caaccagaac tcgctattgt
     8041 atttggtcgt accaaacgcc gtgtggatga attgactcgt ggtttgaaaa ttcgtggctt
     8101 ccgtgcagaa ggaattcatg gcgacctaga ccaaaacaaa cgtcttcgtg tccttcgtga
     8161 ctttaaaaat ggcaatcttg atgttttggt tgcgacagac gttgcagcgc gtggtttgga
     8221 tatttcaggt gtgacccatg tctacaacta cgatattcca caagatcctg agagttatgt
     8281 tcaccgtatc ggtcgtacag gtcgtgctgg taagtcaggt caatctatta cttttgttgc
     8341 tccaaacgaa atgggttacc ttcaaatcat tgaaaacttg actaagaaac gcatgaaagg
     8401 tctcaaacct gcaagtgtag aagaatcctt ccaatcaaaa aaacaggtag ctctcaagaa
     8461 aatcgaacgt gattttgcag atgaaaccat tcgtgccaac tttgagaaat ttggtaagga
     8521 tgctcgcaaa ttggctgctg agtttactcc agaagaattg gcaatgtata tcttgagtct
     8581 gacagtccaa gacccagata gccttccaga agtggagatt gcacgtgaaa aaccactacc
     8641 gtttaaacca tcaggtaatg gtttcggtgg taaagctaag ggaggtcgtg gaggccgtcg
     8701 tggggacgac cgtcgagagc gtgatcgtcg tggcaatggt cgccgtgatg agttcaaaaa
     8761 aggaagtcgt ggcaacgatc gttttgataa ggaaaaacgt taccgtaagg ataataaaaa
     8821 accacgcaat actttaagcg aaaagcaaac aggctttgtt attcgtaaca aaggtgataa
     8881 ataagaaaaa gcggttcaaa atgaatcgct tttttatata aggagaccga atgtgaaaaa
     8941 gacaaataaa attattatat t
//
LOCUS       DAVLBE010000069         8952 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.069, whole genome shotgun sequence.
ACCESSION   DAVLBE010000069 DAVLBE010000000
VERSION     DAVLBE010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8952)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8952)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8952
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.069"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            122..277
                     /locus_tag="VXB91_001798"
                     /pseudo
     CDS             122..277
                     /locus_tag="VXB91_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
     gene            477..3752
                     /gene="rexB"
                     /locus_tag="VXB91_001799"
     CDS             477..3752
                     /gene="rexB"
                     /locus_tag="VXB91_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HEV0471208.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLECLSQQASFSITVTRFAQMARYLVLNDLPAKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMSFLDLENLTDEDKRADLLLIFEKVTAYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQITLVIDGFTRFSAEEERVVDLLHGKGVEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLL
                     RTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQIFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAENLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERQNLNQATEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDLQGLENPAIPTSPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLRPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGKQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKY
                     QGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLEKLDLADGKRLVGEKLKQAWFEKIREE
                     LNR"
     gene            3749..7399
                     /gene="addA"
                     /locus_tag="VXB91_001800"
     CDS             3749..7399
                     /gene="addA"
                     /locus_tag="VXB91_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HEV0471209.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMAERILDQLARGVEISQLFISTFTVKAATELKERLEKKISKKIQET
                     DDVDLKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLPDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKESFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SESFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEIGSLNQEFDSQAYQAVLARVVAISKEKNGRALTNASRKADLKPLADAYNEERKTQ
                     FTKLGQLSDQIAILDYQERYHGDTWKLAKTFQSFMSDFVEAYRQRKRQENAFEFADIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQEGKLILLKANFRSSSEVLSATNDVFERLMDQEVG
                     EINYDNKHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKVHENLYEKLVNAQKMAS
                     SQKGLIHTALAEKLKQFMDILASWRLYAKTHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLASVAVAPPKDAVELMTIH
                     KSKGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLEVKQYPAAK
                     NGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIGEDQLTREAIGELETKSPLQ
                     DSSQADNRQSDTIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQRIDLSQQLTLASLTETLK
                     QVQTSQAVRDKINLDKILAFFDTVLGQEILANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
     gene            7614..8792
                     /locus_tag="VXB91_001801"
     CDS             7614..8792
                     /locus_tag="VXB91_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0471210.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSLIFNGIGRSNC
                     VCGNAIKYAYELFNGVTGQRLFPIGSDCVRHFHRLSLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSDFDERLLKWLWEKGVFKPNRGNQFAPERDYQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERAIKAKQYQKELE
                     KDQRIASQDPIERKQKQTWLLNSYFRELPEEKARFSRLLLEYRKSGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDHRSSAQGSWIEGILLNCLKPFLERLVI
                     "
BASE COUNT         2774 a         1869 c         1897 g         2412 t
ORIGIN      
        1 tagattgaaa taagatacga acagcttgat tagggaaatc aaattaattt ctagaaatat
       61 tttagcatcc acggtgtact attatagttt caatttacta tagttcaatc attctatcaa
      121 gaatattgaa tatataaagg cacgtaatat taaaacttct tctgatatcg aattagagtc
      181 cgatgttgat ggcgataaat cagacaatct accagtcgac attaagatac tgggacaaca
      241 cattgaagtg tattccgtac ctaagaaaca atcataaaac tcaaagcctt gttaccgagg
      301 cttttttatt atgtgatttt cagtagccag acttattcta tctaatacaa gtaaagctaa
      361 gtatttaaga tttagcagat gatgaagaaa agaaaggatg gcctaaatat tttaacagat
      421 ttacgaggct aatcatggta taatataggg tgatgaaaaa ttccaacgag gctgagatga
      481 aattacttta tactgatatt cggacttctt tgacagaaat tctaacaaga gaggcagaag
      541 agctagttgc agctggcaag cgggtcttct acattgcccc caactctctt tcttttgaaa
      601 aggaacgcgc cgtgctggaa tgcttgtccc agcaggcttc tttttcgatt accgtcacgc
      661 gctttgctca aatggctcgt tatctggtct tgaatgattt accagctaaa actactcttg
      721 atgatatcgg tcttgggttg gccttttaca aatgccttgc cgaactcgat cccaaggact
      781 tgcgtgttta tggcgctatt aagcaggatc ctcaattgat ccagcagtta attgagcttt
      841 atcatgagat gaccaaatcc cagatgagtt ttttggactt ggagaattta acagatgagg
      901 ataagagggc ggatttactc ttgatttttg agaaagtaac agcctatctt aatcaaggtc
      961 agttagccca gggaagtcag ttgtcccatt tgattgaggc tattgagaat gacaaggtaa
     1021 gtagtgattt taatcaaatc accttggtca ttgacggctt tactcgtttt tctgctgagg
     1081 aagagcgggt tgtggactta cttcacggca aaggtgttga gattgttatc ggggcttatg
     1141 ctagtaagaa agcctatacc agtcctttta gcgagggcaa tctctaccaa gccagcgtaa
     1201 aatttctcca tcatctggct tctaaatacc aaacgcctgc tcaggactgt tctcaaactc
     1261 atgagaagat ggatagtttt gacaaggcct ctcgtttgtt ggagtcttct tatgactttt
     1321 cagaactcgc tttggatgtc gatgagaaag accgtgaaaa tttacaaatc tggtcttgtt
     1381 tgacgcaaaa ggaggagttg gagctagtag cccgtagtat tcgtcagaaa ttacatgaga
     1441 actcagacct gagctacaag cattttcgta ttctcttggg ggatgtagct tcttaccagt
     1501 tatctctcaa aaccattttt gaccagtatc agattccttt ttatcttggt agaagcgaag
     1561 ccatggctca tcatcccttg actcagtttg tcgagtctat tttagcttta aaacgttacc
     1621 gttttcgtca ggaggatttg attaatcttc ttagaactga tttgtatact gacctcagtc
     1681 agtctgatat tgatgctttt gagcaatata tccgctatct tggtatcaat ggcttgccag
     1741 cctttcagca aatcttcacc aaatcccacc atggaaaatt taatcttgag cgtttgaatg
     1801 tcctccgcct gagaatttta gcacctcttg aaaccctctt tgccagccga aaacaaaagg
     1861 ctgaaaacct cctacaaaaa tggagtgtct ttctaaaaga aggagctgtg accaagcagt
     1921 tacaagattt gacaaccact ttggaagctg tagaacagga aagacaagcc gaagtttgga
     1981 aggctttctg ccatgtttta gaacaatttg cgactgtttt tgctggttca caggttagtc
     2041 tggaagactt cctagccttg ctccattctg gaatgagttt gtcccaatac cgtaccattc
     2101 cagcaacagt ggacactgtt ctggtgcaga gttacgattt gattgcacca ttgactgctg
     2161 actttgtcta tgctattgga ctaactcagg acaatttacc aaaaatttct caaaacacca
     2221 gtcttctgac agatgaagaa aggcaaaacc taaaccaagc gaccgaagaa ggcgttcaat
     2281 tactgattgc cagcagtgaa aatctcaaga aaaatcgcta cactatgctt tccttggtca
     2341 attctgctcg taagcagttg ttcttgtcgg ctccaagcct ttttaacgaa agtgaaagta
     2401 aggaatctgc ctatcttcaa gagttgatcc attttggatt taggcggaga gagaagagga
     2461 tgaatcacaa aggactgtct aaggaggata tggggtccta tcacagtctt ttgtctagtc
     2521 tggttgccta tcaccagcag ggtgagatga gcgatactga gcaagatttg acttttgtca
     2581 aggttctgtc gcgtgtcata ggtaaaaaac tagatctgca aggtctggaa aatccagcta
     2641 tcccaaccag tccaagcagc aagaccttag ccaaggacac cttgcaagct ctctatcctg
     2701 ccaaacagga gttttacctg tctacgtcgg gtttgacaga gttttatcgc aatgaataca
     2761 gttatttcct acgctacgtt ttaggcttgc aggaggaatt acgtttgcgt cctgatgccc
     2821 gtagtcacgg gaatttcttg catcgtatct ttgaacgcgc cttacagttg cctaatgaag
     2881 attcctttga ccaacgtcta gaacaagcta ttcaagaaac cagtcaagaa cgcgaatttg
     2941 aagctattta tcaagaaagt ttggaagccc agtttaccaa ggaagttttg cttgatgttg
     3001 cacggacgac tggacatatt ctccgacaca atccagccat cgaaaccatc aaagaagaag
     3061 caaattttgg tggaaaagac caagccttta ttcaattaga caatggacgc agtgtctttg
     3121 tacgaggcaa ggtggaccgg attgaccgtt tgaaagctaa tggagcgata ggagtagtag
     3181 actacaaatc cagtctgact cagttccagt ttcctcattt ctttaatggg ctcaattctc
     3241 agttaccaac ctatcttgct gccctaaaaa gagaagggaa gcagaacttt ttcggcgcca
     3301 tgtacttgga aatggctgaa cctgtccaat ctctgatggc ggtaaaaagt ctggcaggag
     3361 cagtggtaga agccagcaaa tctatgaaat accaagggct cttcttggaa aaagaaagca
     3421 gttatttagg cgaattttat aacaaaaaca aggctaatca actgacagat gaggaatttc
     3481 agctcctact ggactacaat gcctatcttt acaagaaagc tgctgagaag attttagcag
     3541 gccggttcgc catcaatcct tatactgaaa atggcagaag cattgcccca tacgtccagc
     3601 aacatcaggc tattacaggc tttgaagcca attaccatct gggccaagcc cgtttcctag
     3661 aaaaattgga cctagctgat ggcaagcgtc tggtcggaga aaaactcaag caagcttggt
     3721 ttgaaaaaat aagagaggag ttaaatcgat gaagcttatt ccctttttaa gtgaggagga
     3781 gattcaaaaa ctgcaagaag cagaagcaaa ttcgagcaag gaacagaaga aaactgccga
     3841 acaaatcgaa gctatctaca cttctggtca gaatatcctg gtctcagcat cggctggttc
     3901 tggaaagacc tttgtcatgg cagagcgcat tctggaccaa ttggcgcgtg gtgtcgaaat
     3961 ttctcaactc tttatctcaa cctttaccgt caaggctgca actgaactta aagaacgttt
     4021 agagaaaaaa atcagcaaga aaatccaaga aacagatgat gtcgatctca aacaacactt
     4081 gggtcgccag ttggcagacc tacccaacgc tgccatcgga accatggact ctttcacaca
     4141 aaaattcctt ggcaaacatg gttatctgcc tgatattgca cctaatttcc gtattttaca
     4201 aaaccaaagc gagcaacttc ttctcgaaaa cgaagtcttt catgaggtct ttgaagcgca
     4261 ttaccaaggt aaacagaaag agagctttag tcatttgctg aaaaactttg ctgggcgtgg
     4321 caaggacgaa cggggtctgc ggcagcaagt ctataaaatc tatgacttcc tccaatccac
     4381 cagtaatcct caaaagtggc tgagtgaatc tttcctcaaa ggctttgaga aagctgattt
     4441 taccagtgaa aaagaaaaac tgactgagca aatcaaacaa gccctctggg atttggaaag
     4501 ctttttccgt taccatctgg ataacgatgc caaggagttt gcaaaggctg cctatttaga
     4561 aaatgttcag ttaattctgg atgaaattgg ctccctaaat caggagttcg atagtcaggc
     4621 ttatcaggca gtacttgcgc gtgttgtcgc catctctaag gagaaaaacg gtcgtgctct
     4681 gactaatgcc agccgtaagg ctgatttgaa gcccctggct gatgcctaca acgaagagag
     4741 aaagacccag tttactaaac taggacaatt atcagaccag atagcgattc tcgactatca
     4801 agaacgttat catggagaca cttggaaact agctaaaacc ttccaatctt tcatgagcga
     4861 ttttgtagag gcttatcgtc agagaaaacg acaggaaaat gcctttgaat tcgctgatat
     4921 cagccattac accattgaga ttttagagaa tttcccacaa gttcgtgagt cttatcagga
     4981 gcgcttccat gaagtcatgg tcgatgagta tcaggatacc aaccatattc aagaacggat
     5041 gctggaattg ttgtctaatg gccacaatcg ctttatggtg ggagatatca agcaatccat
     5101 ctatcgtttc cgtcaggcag acccgcagat tttcaatgag aaattccaac gctatgcgca
     5161 aaatccccaa gaaggcaagc tcattctcct caaggcaaat ttccgtagta gttcagaagt
     5221 gctgtcagca accaatgatg tctttgaacg tctcatggac caagaggtcg gcgaaatcaa
     5281 ctatgataac aagcaccagc ttgtttttgc caataccaaa ctgactccca atccagacaa
     5341 caaggcagaa tttctcctct acgacaagga cgatacaggt gaggaagaag agagtcaaac
     5401 agaaacgaaa ctaacaggcg aaatgcgctt agttatcaag gagattctga aacttcatca
     5461 agaaaaaggt gttgccttta aggaaattgc ccttctgacc tccagccgca gtcgtaatga
     5521 ccagattctc ctcgccctgt ctgagtacgg aattcctgtc aaaactgacg gagagcaaaa
     5581 caattatctc caatccctag aagtgcaagt catgctagac actcttcgtg tcattcacaa
     5641 tcccctgcaa gactacgcct tggttgccct tatgaagtct ccaatgtttg gttttgatga
     5701 ggatgagcta gcacgtttgt cccttcagaa agcagaggat aaagtccacg aaaatctcta
     5761 tgagaaactg gtcaatgcac aaaaaatggc aagtagtcaa aaaggcttga ttcacacagc
     5821 tctagctgaa aaactaaagc aattcatgga tatcctagct tcttggcgct tgtatgccaa
     5881 aacccactct ctctatgact tgatttggaa gatttacaac gaccgttttt attatgacta
     5941 tgttggggct ttgccgaatg gtcctgctag gcaggccaat ctctatgccc tagcactgcg
     6001 tgctgatcaa tttgaaaaga gcaatttcaa aggtttgtcg cgttttattc gtatgattga
     6061 ccaagtctta gaagcccagc acgatttggc aagcgtggcc gtcgcaccgc caaaagatgc
     6121 agtagagctc atgaccatcc acaagagtaa agggctggag tttccttacg tctttatcct
     6181 caatatggat caagatttca acaagcaaga ctctatgtca gaagtcattc tcagtcgtca
     6241 gaatggtctt ggtgtcaaat atattgccaa gatggagaca ggggcagtag aagaccacta
     6301 tcctaaaacc atcaaactct ccattcctag tctgacctat aggcagaacg aagaggaatt
     6361 acagctagca agctattctg agcagatgcg tttgctgtat gttgctatga cgcgggctga
     6421 gaaaaagctc tatcttgtcg gcaagggttc tcgtgaaaag ctggaagtca agcaataccc
     6481 agcagccaaa aatgggaaac taaatagcaa tactagactg caagcacgga atttccaaga
     6541 ttggctttgg gctatcagta aagtgtttac taaggacaag ctcaacttta gttatcgttt
     6601 tattggcgaa gatcagttga ccagagaagc tatcggagag ttggaaacca agagtcctct
     6661 ccaagatagc tcccaagcag acaatcgtca gtcagatacc atcaaagaag ctctggaaat
     6721 gctgaaggag gtggaagttt ataatactct tcaccgcgca gctattgaac ttcctagtgt
     6781 tcaaacccca agtcaaatca agaaattcta cgaaccagtt atggatatgg aaggtgtcga
     6841 gattgctggt caaggtcagt cagtaggcaa gaaaatcagc ttcgatttgc cagatttttc
     6901 aaccaaagaa aaggtaactg gagctgagat tggtagtgct actcacgaac tcatgcagag
     6961 aattgacctc agccagcaac taacccttgc tagcctaaca gaaacactca aacaagttca
     7021 aactagccaa gctgtcagag acaagatcaa tcttgataaa attcttgctt tctttgacac
     7081 agtactcggt caggaaattc ttgctaatac cgaccatctc tatcgcgagc aacctttctc
     7141 catgctcaaa cgagaccaaa agagtcagga agactttgtt gtccgtggta tccttgatgg
     7201 ctatctgctt tacgaaaaca aaattgttct gttcgactac aagacagacc gctatgatga
     7261 accaagtcaa ctcgtagacc gctatcgtgg tcagttagct ctatacgaag aggctttatc
     7321 acgagcctat tcgattgaaa atattgaaaa atacttgatt ttactcggta aagacgaggt
     7381 tcaagttgta aaagtataac ttatactctt tgaaaatctc ttcaaaccac gtcagcttcg
     7441 ccttgctgta tatatggtta ctgacttcgt cagttctatc cacaacctca aaacagtgtt
     7501 ttgagctgac ttcgtcagtt ctatctacaa cctcaaaaca gtgttttgag ctgattgcgg
     7561 ctagctttct agtttgctct ttgattttta ttgagtatta gaaaggagac ctcatgacac
     7621 ttccagttag aaaatccctg cacgatgcag ttttacaggc ttcgaaagcg gatacttggg
     7681 aacaagctac caaggaatgg aatgaagttt ccttgatttt taacggtatc ggccgtagca
     7741 attgtgtctg tggaaatgcc atcaaatacg cttatgaact ctttaacggt gtcacaggcc
     7801 aacgcctctt tccaattggt agcgactgtg ttcgtcattt tcatcgattg tcccttgacc
     7861 agcaattgga agaggaagaa aaactgctca gaaaggttga aaatctaacc agaaaagctc
     7921 agaaaaagga aaaaatcaag gtcaataaaa gtgactttga cgagcgactt ctaaaatggc
     7981 tctgggaaaa aggtgttttc aaacccaatc gtggcaatca atttgcgcct gagagagact
     8041 accagctttt cctagaagtc tttcagggag gaagttggac caaggcggaa ccaaagaaaa
     8101 aggctcggat ggaagaagtc cttgaaaagt gtatcaaacc ctttttactt gggaaatcgg
     8161 atgaccaact ctaccttgtc aagctaggca aggagaaaat tgactacgaa caagaactcc
     8221 gtatccaggc agagaaagaa cgcaagaaga gggataaaat cgccaagcaa tatgcagaca
     8281 atctggttct agccatggga cccgcagagc gtgcttatca agattacttt ggctttacag
     8341 agaccctgac tcaagaagaa cgcaagtggg aaaaaattct ttttggtaaa aatagagcag
     8401 aacgggctat caaggccaaa caataccaaa aagagctgga aaaagaccaa cgaattgcca
     8461 gtcaggatcc aattgaaaga aaacagaagc agacttggct cctcaattcc tattttcgtg
     8521 agcttcctga agaaaaagct cgattttcta ggctcttatt agaatatcga aaaagtggtg
     8581 aagtaccctt ttcaactgaa tacctgtccg atcatctcat cgactttttc tataaaatga
     8641 aagcctttga atttgaaatc gcaccagaac aagtccgaga ttttctaaaa aaaagcctgc
     8701 aggaagacca tcgctcatca gcacaaggaa gctggataga aggaattctc ctcaactgcc
     8761 tcaaaccatt tttagaacga ttagtgatat gagtaacacc taccgtgtaa atttcatggt
     8821 aggtgttatt gtacccccaa ataatataaa acaaagtatg aaagcgcatc tcaattttaa
     8881 gacttttttg taaattaaga gtataattaa ggtatactgc cttttctata gataatagat
     8941 aatacactaa ta
//
LOCUS       DAVLBE010000070         8402 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.070, whole genome shotgun sequence.
ACCESSION   DAVLBE010000070 DAVLBE010000000
VERSION     DAVLBE010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8402)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8402)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8402
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.070"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            1..973
                     /locus_tag="VXB91_001802"
                     /pseudo
     CDS             1..973
                     /locus_tag="VXB91_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153874.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            999..1643
                     /locus_tag="VXB91_001803"
     CDS             999..1643
                     /locus_tag="VXB91_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
                     /protein_id="HEV0471211.1"
                     /translation="MLRAGVLDANDGIISIAGVVIGVASATTNIWIIFLSGFTAILAG
                     AFSMAGGEYVSVSTPKDTEEAAVSREKLLLDQDRELAKKSLYAAYIQNGEFKTSAQLL
                     TNKIFLKNPLKALVEEKYGIEYEEFTNPWHAAISSFVAFFLRSLPPMLSVTIFPSDYR
                     IPATVLIVGVALLLTGYTSARLGKAPTKTAMIRNLAIGLLTMGVTFLLEQLFSI"
     gene            complement(1685..3673)
                     /locus_tag="VXB91_001804"
     CDS             complement(1685..3673)
                     /locus_tag="VXB91_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0471212.1"
                     /translation="MFRLTNKLAVSNLIKNRKLYYPFALAVLLAVTVTYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHL
                     ISMTFKELVVFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQTKVVITVLV
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKKGRFLPLQTILGSISLGIGYYLAL
                     TVKDPLTALTTFFIAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSSESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDKGYKIKEKEVFRYTYFAVANQEGTKLTIFEKGQNRVQPKTVFMVFDQK
                     DYENMTGQKLSLSGNEVGLFAKNDGLKGQKALTLNDHQFSVKEEFTKDFIVNHVPNKF
                     NILTTDYNYLVVPDLQAFLDQFPDSAIYNQFYGGMNVDASEEEQLKVAEEYENYLNQF
                     NAQLDTEGSYVYGSNLADASSQMSALFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQTINKQVLTVFFLPLLFAFIHLAFAYHMLSLILKVIGV
                     LDTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
     gene            complement(3675..4433)
                     /locus_tag="VXB91_001805"
     CDS             complement(3675..4433)
                     /locus_tag="VXB91_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0471213.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPSRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVVTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSAALLDVFDEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQMFQEISDTLTVMASEVN"
     gene            4861..5052
                     /locus_tag="VXB91_001806"
     CDS             4861..5052
                     /locus_tag="VXB91_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0471214.1"
                     /translation="MKHKEHILIGLLYLLSPFIGQLLVEHTHFIGTEFTGTAYVICWL
                     SVVISIHHFSKNVLSQQQK"
     gene            complement(5406..5678)
                     /locus_tag="VXB91_001807"
     CDS             complement(5406..5678)
                     /locus_tag="VXB91_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEV0471215.1"
                     /translation="MNSKFYKMRRNRMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGWFW"
     gene            complement(5737..6186)
                     /locus_tag="VXB91_001808"
     CDS             complement(5737..6186)
                     /locus_tag="VXB91_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HEV0471216.1"
                     /translation="MKLTDYVKQVSLEDFGRAFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQKLGMEVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPLKLYRCQSCQQRYQRKRRIDTKRYRCGLCRGKLLLINQPED"
     gene            complement(6173..8302)
                     /locus_tag="VXB91_001809"
     CDS             complement(6173..8302)
                     /locus_tag="VXB91_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HEV0471217.1"
                     /translation="MDKKYEKISQDLGVTLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIVDLEKEAEKFVCEGFATGKEALTGAVDI
                     LVEALSEDVTLRSMTYQEVLRHSKLTSQAKDESLDEKQVFQIYYDFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFATRFKVKNAYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNVNTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRSQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYAAVKELFKCL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGQKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVAVGD
                     LVTVWVKKIDTEREKVNLSLLAPNETD"
BASE COUNT         2546 a         1765 c         1652 g         2439 t
ORIGIN      
        1 agccaaacat ttgacaatcg atagccgtcg cttaatcgaa agatggaaaa aagaaggaaa
       61 atcaaataga gaaattgcct ctctacttgg aaaagctcct caaactatcc acactgaaat
      121 caagcgtagg acagtccgac aatgtcttgg aaaagggcgc ttcaaagagg tttattctgc
      181 cgactatgct caacagtctt atgaaaataa tcgcaagcac tcggtcaaga gatcaagcgt
      241 gaccaaggaa ctaaaggaaa agattctcca ctatcataac caaaaatttt cgcctgaaat
      301 gatggttatg gctaaagggg ttaacgtggg aatttcaacc atttactatt ggattcatca
      361 tggaaaattg gggttaagca agcaggatct gctttaccct agaaaaggaa aagcgcttaa
      421 gaaacaggct agcaccaact ttaaacctgc tggtcaatcc atcgaacagc ggcctgaagc
      481 tatcaatctt cgcttggaga atgggcatta tgagattgat acggttctac ttacgagatc
      541 gaaaaactac tgcttgcttg tcttgacgga tcgaaagagt agacatcaga tcatccgatt
      601 gattccaaat aaaagtgctg aggtggtcaa tcaggctcta aaactcatct taaaacaaca
      661 caagattctt tccatcacgg cagataatgg aacggaattc aatcgcttgt ttgatatatt
      721 ttctgaggag cacatctatt atgcgcaccc ctatgcctct tgggaaaggg gaactaatga
      781 gaatcacaac aggctcattc gtagatagtt acctaaggga accaagaaaa tgactcccaa
      841 agaagtcgca ttcatcgaaa agtggattaa caactatcct aaaaaatgct tggactacaa
      901 gtcacccaga gaagacttct ggatggctaa cttgaacttg aaatttagcg tcagaaacaa
      961 atcacgaaat tgattcaaat tttgcaggtc gtttaaatat cctgcgtgcg ggtgttcttg
     1021 atgctaacga tggaattatt tccattgctg gtgtggttat cggagttgcc agtgccacga
     1081 ccaatatctg gattatcttt ttatcaggtt ttacggctat cttagctggt gccttttcaa
     1141 tggctggtgg agaatatgta tccgtttcaa ctccaaaaga taccgaggaa gctgccgttt
     1201 cgcgagaaaa actcttgcta gaccaagata gggaactagc caaaaaatcc ctctatgctg
     1261 cttatatcca aaatggagaa ttcaaaactt ctgcccaact cttgaccaat aagatctttc
     1321 ttaaaaatcc actcaaggct ctggtagagg aaaaatatgg gattgagtat gaagaattta
     1381 ccaatccttg gcacgctgcc atttctagct tcgttgcctt tttccttaga agtttgcctc
     1441 caatgctgtc agtgaccatt tttccaagtg attaccgcat ccctgctacc gtccttattg
     1501 tcggtgtggc ccttcttctc actggttaca caagtgctag acttggaaaa gccccaacca
     1561 aaacagctat gattcggaac cttgctattg gtctcttgac catgggagtt accttcctgc
     1621 tcgaacaact tttcagcatt tagaatacaa gaaatacctc gattttgaag tcgaggtatc
     1681 ttttttacat ttgcacaatc ttgcgataac ttcttgaagt aatcatgaaa atcagcacat
     1741 aggcgatgag gaagatagcg cagatagaca aggtcacaat caacatcata gtcgtatcca
     1801 gtacaccaat cacttttaaa atcaggctaa gcatatggta ggcaaaggcg agatgtatga
     1861 aggcaaagag caaaggaagg aagaaaacag ttaaaacctg tttgttgatg gtttgcttga
     1921 tttgcttttg gtccaaaccg actttctgca agataataaa gcgttcacgg tcttcgtagc
     1981 cttcagaaat ttgtttgtag tagatgacca gaacagttcc gaccataaag ataatggata
     2041 ggaaaatacc gataaagaag acaccaccaa agagggcact catctgagaa ctagcatctg
     2101 ctagattgct accataaaca tagctacctt ctgtgtctaa ttgagcatta aattgattga
     2161 ggtagttttc atactcctca gcgaccttga gttgttcttc ttcgctggca tctacattca
     2221 taccaccgta aaactgatta tagatagccg aatctgggaa ttgatccaaa aaggcttgta
     2281 aatcaggaac aacaaggtaa ttgtaatcag tagtcaagat attaaactta tttggaacat
     2341 ggttgacaat aaaatcttta gtaaattctt ctttgacaga aaattgatga tcatttagag
     2401 ttagagcttt ctgtcctttc agtccgtcat ttttggcaaa gagaccgacc tcatttcctg
     2461 atagagacag tttttgacca gtcatatttt cataatcttt ttggtcaaat accatgaaaa
     2521 ctgtttttgg ttggacacgg ttttgtcctt tttcaaaaat agttaacttg gttccttctt
     2581 gattcgcaac agcaaagtaa gtgtaacgaa atacttcttt ttctttaatc ttataacctt
     2641 tgtcacttgc aaactggctc aagagtttgt ccaagtcttc tttttcaaca ttttgccctg
     2701 aaaccccaaa atcatgagga tttagaactt ttttaaagct ttctgaggaa ttgaaaatgc
     2761 ttgtcgctgc tgacatggtt accaaaacca ttgttgacaa gatagcgatg gtggctagtc
     2821 caactgcatt tttcttcata cggaaaatca agttagaaac agatatgagg ttatttggtt
     2881 ggtaatagta tttcttattt ttctttaaga tttggaggaa aacggtaatc cctgcattaa
     2941 acaagagata agtcccaaag ataaccagta aaacagctat gaagaaggtt gttaaggctg
     3001 taagaggatc ttttaccgta agggcgagat aatagccaat tcctaaactt atggaaccaa
     3061 gaatggtttg gagaggaagg aagcgacctt ttttctctcc actagctttc tcacgagaga
     3121 gctggagggc attcatacgg gcgattcgaa gggcattcag gaacatgagg cctaggaaaa
     3181 tcaaaccgaa gacaacaagc actgtaatga caactttcgt ctggaaggta gcaaccagct
     3241 caaccttcaa tttcattagt ttgagcagga aagcgaaaat taacttgtca aacaaggctc
     3301 caataccgat acccgctcca acagttagaa tcccaaatac cactaactcc ttaaaggtca
     3361 tactgataag atgacgcttc tccaagccca acatgccata aattcctagt tccttggaac
     3421 ggttcttcat gacaaaacta ttggcataga gaacgataat ggctgacgca agggtgacga
     3481 caaacatacc aaatccaagt gtagcctgaa tggttgttcc tccacggatt tccgcaatct
     3541 taggattgaa ggttagagag taaaagagat aggtgacagt gactgccaag agaacagcca
     3601 gcgcaaaagg atagtagagt ttgcggtttt taatcaagtt cgataccgct aacttattgg
     3661 ttaatcgaaa catactaatt cacctcgctt gccatgacag tcaaggtatc agagatttct
     3721 tggaacatct gacgttctgt cttctctcca cggtagattt gattgtaaag aatgccgtct
     3781 ttgataaaga gtacacgttt agctctgcta gctgctgctg ttgagtgggt taccatgaga
     3841 atggtttggc cgcgctcatt gatttcatca aagacatcaa gtaaggctgc agatgacttg
     3901 gagtcaagag ctcctgtcgg ttcgtccgca aggagaattt caggttctgt gatgatggcg
     3961 cgggctactg ctacacgctg tttctgacca ccagaaatct cgtaagggta cttctcttgt
     4021 aattggttta ttcccagatt ctcagctgtc accaccaatt tcttcatcat ctctgtaata
     4081 ggtcttcttg acaagacaag cggaagcaag atattgtcct ttacagatag agtatctagc
     4141 aagttaaagt cttggaagac aaagcccaac ttttcacgac ggaagctaga ggcctgtgaa
     4201 tttttaatgg ttgcggtgtc agttccattc aagtaaacct gaccacgact tggtttatcc
     4261 agcatagcta gaatattgag aagagttgat ttaccagaac cagactcacc catgatggca
     4321 acgtagtcac ccttttcgac ggtaaagtga atatccttga gggcttctac ttggttgccc
     4381 tgaaaacgtg ttttataaat tttttgaacg tgttttacat ctaaaagtgt catgagaatc
     4441 tcctttctta atatcccatc aaatgaaatg tagcttgcat catagtgcat cccagctgaa
     4501 cgcgctcaat ttctttgtga cttggttttc tagttttctt atgtaagatt tgtttcatga
     4561 tgttactcct ttgttcttta tgagtctagt ttacatcaaa aaaagaccgc ttgccataac
     4621 ctaaccttac aaaagagact ttaatcttac atttttgtaa gattgggtga aatataagca
     4681 aaattactta gaaaatgatt tgatttccta tttttaaagt tgtaaaatat aagtgtgaaa
     4741 aggcttactt tgaaaaggag gaagcgggaa ctaacatttt agtaaggtta cctagataac
     4801 ataccattca atttaacact tgcaagtcgt tcaacctata aggaaagaag gtgcgcttta
     4861 atgaaacaca aagaacatat actcatcgga cttctctatc tgctctctcc attcatcggt
     4921 cagctcttag ttgaacacac acactttatc ggtacagaat ttaccggcac tgcttatgtt
     4981 atttgctggt tatcagttgt tatcagcatc caccattttt ccaaaaatgt attgtctcag
     5041 cagcaaaaat agattaaaaa actgagttta aattactgct tttataataa aatgaaataa
     5101 gaacaggaca aatcgatcag gatagtcaaa tcgatttcta acaatgtttt agaagtagag
     5161 gtgtcctatt ctagttccaa tccactatag tttgtggatg aagctggcga aatattatta
     5221 atactattca aaaatcaaag tgcaaactat gtcaacttca cattgccgac taaattacag
     5281 cctgtggctg gcttcctagt ttgcactttg atttttattg agtataaaag taaaaaagct
     5341 ttaaatcaag cagtttagac tattgattta aagctttttg cttattccaa atcttctgta
     5401 gaacctcacc aaaaccagcc ttcattgtcg tcaatggctt gggcttcttt gcgtttacgt
     5461 gggcctgttc cgtacatttc tgcttcgatt tcttccttgg taggcatgat agaagctagg
     5521 atgatataga taatcacgcc aagtccaaag tttgcaactg taaaaatagc aaacaagaaa
     5581 cgaactaggg taacatcaaa attccacttg tctgacagac ctgccagaac tcctgaaatc
     5641 atgcgattgc gtctcatttt ataaaattta ctgttcatga tatttcctct ttctgctagg
     5701 ttagacatag tatatcacgg ggaggctcgg ctttcatcag tcctcaggct gatttatcag
     5761 aagcaattta cctcgacaaa gtccacagcg atagcgtttg gtatcaatcc tacgcttgcg
     5821 ctgatacctt tgctggcagg attgacaacg ataaagcttg agtggtttag agttactatt
     5881 gggcaaggat ggtacaaacc gtaatccatc cactgctttc aaaagttcct taaaatcccg
     5941 atccttgtgt tgatagccct tcccttggaa ataaaggtga taatgacaga gttcatgtcg
     6001 gacaattttc ctaaaaacct ccatacccag tttctgataa accttgggat taaaatccag
     6061 atgcccatct ttggggaaaa atcgcccacc tgtcgaacgt agacgcctat tccactggac
     6121 atgatggata aaagctctcc cgaagtcttc tagtgaaacc tgcttgacat aatcagtcag
     6181 tttcatttgg agcgaggagc gacagattaa ctttttcacg ttcagtatca attttcttga
     6241 cccaaacggt caccaaatct ccaactgcca ccacttgact agggtgtttg ataaacttgc
     6301 gactcatatg agaaatatga atcaagccgt cctcgtgaat cccgatatca acgaaggcac
     6361 cgaagtcaac aacgttacgc acaacacctt ctagcttctg acctaccact aggtctttga
     6421 tatctaggac atcttggcga agcacaggtg cgtcaaagga atcacggaaa tctcgacctg
     6481 gtttgagaag atctgcaatg atatctttaa gggtttctgg accgaggtct agctcttgag
     6541 ccatttcctt gactgaaagc gacttgagtt tgctttgggc ctcttcattc agatccttaa
     6601 tgtccaagca tttgaagagt tccttaacgg cagcgtaatt ttctgggtga actcctgtat
     6661 tatcaaggat attgctactt tcagggatac ggaggaaacc agcagcctgt tcaaaagcct
     6721 tggcccccaa acgaggaact ttcttgattt gggagcgtga agtgattttt ccctcttcct
     6781 cacggtattt gacgatattt tcagaaatgg ttttattgag tccagctacg tgtgaaagaa
     6841 gagctgggct agctgtattg acattgacac caacttggtt aaccactgta tcgacaacaa
     6901 agtccagact ctcagatagt ttcttctgac tgacatcgtg ttggtattga ccgacaccaa
     6961 ttgacttagg atcgattttg accaattccg caagaggatc ttgcaaacga cgggcgatag
     7021 aaatggcaga gcgtttttca acggtcaagt ctggaaactc ctgacgagca agttcgctgg
     7081 cagaatagac agaagcacca ctttcattaa cgataacata gctgacttca gggaaatctt
     7141 tcagaacttc cgctacaaaa gcttcacttt cacgactggc cgttccattt ccaatggcaa
     7201 taatctctac accgtattga ccaattaaat ctgctaaatc tttcttggct tcttcgattt
     7261 gacgagctga tgctggttta acaggataaa taacctgagt tgtcagcatt tttcctgttg
     7321 catccacgac agctagcttg gcacctgtac gaaaggctgg gtcaaaccca agaaccacgc
     7381 gccctttcag tggagcaacc aagaggagat tgcgcagatt gtcagaaaaa agttggatag
     7441 ctccctcttc agctttctca gttaattctg tccgaatacg acgctcaata gcaggcaaga
     7501 cctttttctt aacggattgc tgaacaactt catcaatata agcatttttc accttgaaac
     7561 gagtagcaaa gaaggcaaga atacggtccg tcgcatgttc aaaaccgatc ttcaagacac
     7621 caagtttctc cccacgattg agagccaagg tacgatagcc ttgcatagtt ccaactgtct
     7681 ctgaaaaatc ataataaatc tgaaaaacct gcttttcatc aagactttca tccttggctt
     7741 gagaagtgag tttagagtgt ctcagcactt cctgataagt catagaacgc aaggtcacat
     7801 cttccgataa ggcttcgacc aaaatatcaa ctgcaccggt caaggcttcc ttgccagtcg
     7861 caaatccttc acagacgaac ttttcagctt ctttctctaa gtcaactata ttctgcaaaa
     7921 tcaaacgagc aagaggaaag agtccagctt cacgggcaat ggttgccttg gtacgacgct
     7981 tttccttata aggaagatag agttcttcaa cgtctgctaa tttttcggca actaagatag
     8041 cttcttccaa ttccttggtc aacttacctt gttcttgaat cttagctaag acagcttcct
     8101 tacggtcatt gagatttgtc agacttttat ccaaatcaat aatagcctta atcgccacct
     8161 catccagact accagtcatg tccttgcgat aacgcgcgat aaagggaata gtcgcccctt
     8221 cagctgtcaa acttagaacg gtatcaattt gctttaacgt cactcccaaa tcctgagaga
     8281 ttttttcata ttttttatcc ataaatctat tataccacaa gctggaaggc tttctccaat
     8341 ccttttcata ctcaataaaa atcaaaaagc aaactaggaa gctagccgta ggctgctcaa
     8401 aa
//
LOCUS       DAVLBE010000071         8312 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.071, whole genome shotgun sequence.
ACCESSION   DAVLBE010000071 DAVLBE010000000
VERSION     DAVLBE010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8312)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8312)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8312
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.071"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            <1..241
                     /locus_tag="VXB91_001810"
     CDS             <1..241
                     /locus_tag="VXB91_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="phosphate uptake regulator PhoU"
                     /protein_id="HEV0471218.1"
                     /translation="CYREEQSGCLDMVVIQKQNEIEELSTNIEKKIMNYIFEDDGNVS
                     EVIGALDIIHHLDKIAHTTQSIYKWIMYRKYGNIN"
     gene            254..1729
                     /gene="galT"
                     /locus_tag="VXB91_001811"
     CDS             254..1729
                     /gene="galT"
                     /locus_tag="VXB91_001811"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEV0471219.1"
                     /translation="MKTIIDNFVDRVIEYGMYNEIDKIYVKNRVLALIGEEGTDRISD
                     ENDLKQIKDYLVEIALKNGKIKDLIEEKECLGAELMNFIVPLPSRLNDIFWSSYDISP
                     QEAVEEFYKLSKDSDYIKTSAIAKNIEFRASTKYGELEITINLSKPEKDPKTIAAEKL
                     VKATNYPKCLLCMENEGYQGRINYPARSNHRIIRLKLGDEVWGFQYSPYLYFNEHAIF
                     LNSQHVPMAITSKTFEQLLEIVDILPGYFAGSNSDLPISGGSILSHNHYQGGKHIFPM
                     EKAKFESEFRFKDFEDVNAGIVKWPMSVIRLQSENKNRLLDLATKILNKWREYSDLEV
                     DIIAMTEDVPHHTVTPIARKVDGRYELDIVLRDNHTTEQYPDGVFHPHQDVQHIKKEN
                     IGLIEVMGLAILPPRLKPELEEVGKYLLGEDNAIADYHLEWADQLKEKYPRINKEEVN
                     SVVQHEAGQVFARVLEDAGVYKNTPSGHEAFMRFVKSVGIN"
     gene            1742..2722
                     /gene="galE"
                     /locus_tag="VXB91_001812"
     CDS             1742..2722
                     /gene="galE"
                     /locus_tag="VXB91_001812"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEV0471220.1"
                     /translation="MAILVTGGAGYIGSHTVVELLNLGKEVIIVDNLSNSSILVLDRI
                     EAITGIRPVFYELDVCDKPALRKVFEQESIDAAIHFAGYKAVGESVQKPVMYYKNNIM
                     STLALVEVMSEFNVKKIVFSSSATVYGINNQSPLIETMQTSATNPYGYTKVMLEQILK
                     DVHVADSEWSIALLRYFNPIGAHESGLIGEDPSGLPNNLMPYIAQVAVGKLSELSVFG
                     NDYDTLDGTGVRDYIHVVDLAIGHIKALEKVSEKTDVYIYNLGSGEGTSVLQLVNTFE
                     SVNKIPIPYKIVPRRSGDVATCYANADKAYKELNWRTTKSIEDMCRDTWN"
     gene            2931..3590
                     /locus_tag="VXB91_001813"
     CDS             2931..3590
                     /locus_tag="VXB91_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HEV0471221.1"
                     /translation="MKNLTKIKFKENGEFNHFPGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIHMRITEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVCFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVPYHEKF
                     K"
     gene            3615..4682
                     /locus_tag="VXB91_001814"
     CDS             3615..4682
                     /locus_tag="VXB91_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV0471222.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDVKEMPKDWT
                     ELASKYKGKYSIYGLQGGTGRAILASILVRYLDEKGDLGVSEKGWGVAKEYFANAYTL
                     QKGESSVVKALDKESPIQYGMIWGSGALIGQKEQNVEFKVMTPEIGVPFVTEQTMVLS
                     TSKKQALAKEFIDWFGQSEIQVEYSKKFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVK"
     gene            4785..5795
                     /locus_tag="VXB91_001815"
     CDS             4785..5795
                     /locus_tag="VXB91_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0471223.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            5807..7498
                     /locus_tag="VXB91_001816"
     CDS             5807..7498
                     /locus_tag="VXB91_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV0471224.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDSNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            7501..8211
                     /locus_tag="VXB91_001817"
     CDS             7501..8211
                     /locus_tag="VXB91_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HEV0471225.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
BASE COUNT         2816 a         1154 c         1638 g         2704 t
ORIGIN      
        1 ttgttataga gaggaacaat ctggatgttt agatatggtt gttatacaaa aacagaatga
       61 gatagaagag cttagtacaa atattgaaaa gaaaataatg aattacatat ttgaagatga
      121 tgggaatgtt tctgaagtaa ttggtgcttt agatattatt catcaccttg ataaaattgc
      181 tcatactacg caatcaattt ataaatggat aatgtataga aaatatggga acataaatta
      241 gaaagaaaaa tatatgaaaa caattattga taattttgtt gatagagtaa ttgaatacgg
      301 aatgtataat gaaattgaca aaatatatgt gaaaaataga gtactagcgt taataggtga
      361 ggagggaact gatcgcattt ccgatgaaaa tgacctgaaa caaataaaag attacttagt
      421 ggaaatcgcc ttaaaaaacg gtaaaattaa agatttaatc gaggaaaagg aatgtttagg
      481 agcagagtta atgaatttca tagttccttt acctagtcga ttaaatgata ttttttggag
      541 ttcatatgat atatcacctc aagaagcagt tgaagagttt tataagttaa gtaaagatag
      601 tgattatatt aaaacttctg ctattgctaa gaatattgag tttcgagcat caactaaata
      661 cggagagcta gagattacga taaatttgtc aaaacccgaa aaagatccaa aaacaattgc
      721 tgctgaaaaa ttagtaaaag ccactaatta tcccaaatgt ttactatgta tggaaaatga
      781 aggatatcag gggcgaataa attatccagc acgttcgaat catagaatta ttcgattgaa
      841 acttggtgac gaagtatggg gattccaata ttctccctac ttatacttta atgagcatgc
      901 gatattttta aatagtcaac atgtaccaat ggctattacc tctaaaacat ttgaacaatt
      961 attggagatt gttgatattt tgccaggata ttttgctggt tcaaattctg atcttcctat
     1021 ctcaggaggc tccattctta gtcataacca ctaccaggga gggaaacata ttttcccaat
     1081 ggaaaaagca aaatttgaga gtgaatttcg ttttaaagac tttgaggatg ttaatgctgg
     1141 tattgtaaaa tggccaatgt cagtaattag gttacaaagt gaaaataaaa atcgcttgtt
     1201 agatttagct actaaaattc taaataagtg gagagaatat tcagatttag aagtagacat
     1261 cattgctatg actgaagatg tcccacacca tacggtgact cctattgctc gtaaagtgga
     1321 cgggagatat gaattagata ttgttctaag agataatcat actactgaac agtacccaga
     1381 tggtgttttc catcctcatc aagatgtaca acatattaaa aaggaaaata tcgggttaat
     1441 cgaagtgatg ggacttgcga tattaccacc tcgtttgaaa ccagagttag aagaagttgg
     1501 aaaatatctt ttaggagagg ataacgcaat tgcggattat catttagaat gggccgacca
     1561 attgaaagaa aaatatcctc gcattaataa agaagaggtt aatagcgtag ttcaacacga
     1621 agcaggacaa gtgtttgcga gagttctgga agatgcagga gtttataaga atacaccgtc
     1681 tgggcatgaa gcgtttatga gatttgttaa gtcggttgga attaattagg aggaaacaaa
     1741 aatggcaata ttggtaacag gcggagctgg ttatattggt agccataccg tagtagaatt
     1801 actaaattta ggaaaggaag tcatcattgt cgacaacctt tcgaactcta gcatcttggt
     1861 gctagaccgt attgaagcaa ttacaggaat acgtcccgtg ttttacgaat tagatgtttg
     1921 tgataaacca gcattgagaa aggtatttga acaagaatcg attgatgctg caattcattt
     1981 tgcaggttat aaagctgtcg gagaatccgt gcaaaagcct gtgatgtact acaaaaataa
     2041 tattatgagt acattggcac ttgttgaagt gatgtcagaa tttaatgtta aaaagattgt
     2101 cttttcttca agtgcgactg tatatggaat taacaatcag tcacctctaa ttgagacgat
     2161 gcaaacaagt gcgacaaatc cttatgggta tacgaaagtg atgcttgagc aaattttaaa
     2221 agatgttcat gtggcagatt cagaatggag tattgcgttg cttcgttatt tcaatccaat
     2281 tggtgctcat gagtctggtt tgattgggga agatccctca ggacttccta acaacttgat
     2341 gccttatatt gcacaagtag cggtaggtaa gctatcagag ctaagtgtgt tcggaaatga
     2401 ttatgatacg cttgatggta ctggtgtgcg tgattatatc catgtagtag atttagcaat
     2461 aggacatata aaagctttag aaaaagtatc tgaaaaaaca gatgtttata tctataacct
     2521 aggctcggga gaaggcacta gtgtattaca acttgtaaat acatttgaaa gtgttaataa
     2581 gatccctatt ccttataaaa tagttccaag acgttcagga gacgttgcaa cttgttatgc
     2641 aaatgcagac aaagcatata aggaattaaa ttggaggaca acaaaatcga ttgaagacat
     2701 gtgtagagat acatggaatt agcaatcaaa aaatcccaat ggctataatt gatgatactg
     2761 tctatatgag tgctgtattt tggaaaaatt acttaacctt ttaatgaaat gcatatttaa
     2821 tgaaagataa attaaaaaaa atgtttgaca gcgcttgaca aaggaaacgg tttcattgta
     2881 taatgtaaac atagtgacac cgatgtcaat ataaaaaaga aggtctttat atgaaaaact
     2941 taacaaaaat taagttcaaa gaaaatgggg aatttaatca tttccctggg aatacagttg
     3001 tagcaaatct ttatactaaa caagatttga tggaagttgt tgatattatt caatcacgtt
     3061 atagagaatt accatttatc gataagttta ctttaactcc aaggaattct attcacatga
     3121 ctgtaattga attgttgtgc catgaaaatc gtgaaacgga gttttggagc agtaatcttc
     3181 ctctagatac acctttacag gaaatacatg attactttgc taaacaactt gaaatttttc
     3241 cattgttgga tgaagaaatt catatgcgta taactgaaat gggaaaacaa aacatactag
     3301 ttgaacctgc agatgaagct tctgcaaaga gattagaaga aattcgtact tatgtctcag
     3361 aaaaagcagg tgtttgtttc cctaatcatg atagatatca attccatatt tcaattgggt
     3421 atcttcggat tcctctaacc gaagaggagg aagaagagtt tactaaagtc agagcagaat
     3481 taactgaaat tttattagag aagattccaa ctattactgt aaaccgtatt gactatactg
     3541 tatttgaaga tatgagacaa tttgttccat atcacgaaaa atttaaataa aataataaaa
     3601 aaggagaact tatcatgaaa aaaatgaaag tttggtctac tgtacttgca acgggagttg
     3661 ctcttactac acttgctgct tgctctggag gttcaaattc tacgactgct tcttcatctg
     3721 aagaaaaagc tgataaaagt caagaattag ttatctattc gaactcagtc tcaaatggtc
     3781 gtggtgattg gttaactgct aaagcaaaag aagctggttt taatataaaa atggttgata
     3841 tcgctggcgc tcaattagca gaccgtgtta ttgctgagaa gaataatgca gttgcagata
     3901 tggtatttgg aattggtgct gttgactcaa ataaaattag agatcaaaaa ttactagtac
     3961 agtacaagcc taaatggtta gataaaattg atcaatcttt atcagataaa gataattatt
     4021 ataatcctgt gattgttcaa ccattagttt taattggggc gcctgatgta aaagaaatgc
     4081 ctaaagactg gacagagtta gctagtaagt ataaaggtaa atattcaatt tatggtcttc
     4141 aaggtggtac aggacgggca attctagcaa gtatcttagt tcgttacctt gatgaaaaag
     4201 gagatttagg cgtatcagaa aaaggatggg gagttgcaaa agaatacttt gcaaatgcct
     4261 atactcttca aaaaggtgaa agctcagttg ttaaagcgtt agataaagaa agcccaattc
     4321 aatacggtat gatctggggt tctggagcgt taatcggaca aaaagaacaa aatgttgaat
     4381 tcaaagttat gactcctgag attggtgtac catttgtaac tgaacaaact atggttttaa
     4441 gcactagtaa aaaacaagcg ttagctaaag aatttattga ttggtttggt caatcagaaa
     4501 ttcaagtaga atatagtaaa aaatttggat ctattcctgc aaataaagat gccctaaaag
     4561 agttacctga agatacgaaa aaatttgttg atcaagtgaa accacaaaat attgactggg
     4621 aagctgttgg aaagcatttg gatgaatggg tagaaaaagc tgaattagaa tacgtaaaat
     4681 aagaaataag agttattttt tatgtccaag tctctctatt atttctaaat ttaaggaaga
     4741 aataaagaga ggcttttggt ttagtaatag agggagttag tgagatgatt aaatttgata
     4801 atattcaaat taaatatggt gattttgttg caattgataa tctgaattta gatatacatg
     4861 aaggggaatt ctttacattt cttgggcctt caggatgtgg taaatcaact actttgagag
     4921 cattggtagg ttttttagat ccatcatcag gaagtattga agttaatgga acagatgtca
     4981 ctcatttgga acctgaaaag cgtggaattg gtattgtatt tcaatcttat gcgctatttc
     5041 caactatgac tgtttttgat aatattgcat ttggtttaaa agttaagaag gtagctccag
     5101 atgttattaa agctaaagta tcagcagtgg cagcaaaaat taagatctct gatcaacagt
     5161 tacagcgtaa tgtatcagaa ttatctgggg gtcaacaaca aagggtagca ttggctcgtg
     5221 ctctggttct tgaacctaaa attctttgtc tagatgaacc attgtcaaac cttgacgcaa
     5281 aattacgtgt agatttgaga aaagagttga aaagacttca aaaagagtta ggtattacta
     5341 ctttatatgt tactcatgat caagaggaag ccttgacttt atctgataga attgcagtct
     5401 ttaacaatgg atacatcgaa caggtcggta caccagtaga gatttatcat aattctcaaa
     5461 ctgaatttgt atgtgatttt attggagata ttaatgtttt gaccgatgaa acagtccacg
     5521 aagtattact gaaaaataca agcgttttct tagaggataa aaaaggttac attcgattag
     5581 agaaagttcg attcaatcgt gaaactgaac aagattttat tctaaaaggg acaattattg
     5641 atgttgagtt ttctggagtt acaattcact atacaataaa agtttctgaa agtcagattc
     5701 ttaatgtaac aagtattgat agtcaggctg ctattagatc tgtcggagaa agtgtggaat
     5761 tatttatcac accatcagac gttctgcaat tttaaggagg tgcagtatgc gtcataaatt
     5821 aaatttaaaa gattggctta ttcgtttagg gttaatctgg ttcttagtaa catttattat
     5881 ttatccaaac tttgatctag tagtgaatgt atttgtaaaa ggaggagaat tttcccttga
     5941 tgctgtacat cgtgttctaa aatctcagag ggcacttcag agtattatga acagttttaa
     6001 gttagcattt tcactcatta ttacagttaa tgtcgtaggt attctttgtg ttctatttac
     6061 agagtacttt gatattaaag gtgctaaaat tttaaaatta ggttatatga cctctttaat
     6121 ttatggagga gtggttttag cgactggata taaatttgtc tatggtcctt atggattgat
     6181 tacaaaattt ttacaaaatg ttatcccttc tttagactct aactggttta ttgggtatgg
     6241 tgcagtctta ttcattatga cattttcagg aactgctaat catacattgt ttttaacaaa
     6301 tacaattcga agcgttgact atcacactat tgaggctgct cgaaatatgg gagcaaaacc
     6361 atttactgtt ttccgaaaag tagtgttacc aaccttaatt ccaactctat ttgcacttac
     6421 tattatggtt tttcttagtg gtttatctgc agtagcagca cccatgattg ttggtggtaa
     6481 agaatttcaa actataaatc caatgattat tacatttgca gggatgggga attctcgtga
     6541 tttagctgcc ttacttgcaa ttattttagg tattgcaact acaattttgc ttactatcat
     6601 gaataagata gaaaaaggtg gaaattatat ttctatctct aagactaaag cgcctcttaa
     6661 aaaacaaaaa attgcgtcta agccttggaa tatcattgct cacattgtag catatggatt
     6721 gttcacagtt ttcatgcttc cactaatttt tatagtatta tactcattta cagatccagt
     6781 tgcaattcaa acaggtaact taacattatc aaactttact ttagaaaatt atcgcttatt
     6841 ctttagtaat agtgcggcat tctctccatt cttggtcagc tttatttatt ctattattgc
     6901 tgcgacaaca gcaacaattc tcgcagttgt atttgctcgt gttgtcagaa aacataaatc
     6961 tcgttttgat ttcttatttg aatatggtgc tctacttcct tggttactac caagtacact
     7021 tttagcagta agtttattat ttacttttaa tcagccacaa tttcttgtct tgaatcagat
     7081 tttggtaggt agtttggtaa ttctacttat tgcatatata gttgtaaaaa tcccattttc
     7141 ttatagaatg gtacgtgcta ttttatttag tgttgatgat gagatggaag atgcagcaag
     7201 aagtatgggt gcttcacctt tttatactat gatgaaggtt atcattccat ttattttacc
     7261 ggttgttctc tctgttattg ctttaaactt taactcttta ttaactgact tcgacttatc
     7321 tgtattcctt taccatcccc tagctcaacc attaggtatt acgattcgat ctgcaggtga
     7381 tgaaacagca acatctaatg cacaagctct ggtatttgtt tatacaattg ttctgatgat
     7441 catttctgga acggtattat acttcacaca aagaccgggg cgtaaagtaa ggaaataatc
     7501 atgacagcca ctagtcttgg gttatcaaat attgaaatag ttgtcaggat tgttttatca
     7561 gtagtcattg gtagtataat tggtttagag agagggagca aatcccagcc tgcaggcatc
     7621 cgaacttata gtattgtttg tctagctgca tgtttgatta tgatgacgaa tgaatacgta
     7681 tcttataaat ttgggacagg agatcctaca cgattaggag ctcaagttat atcaggtgtg
     7741 ggttttctag gcgctggaac gattcttatt acagataaaa agaaaattac aggtctgaca
     7801 actgcagcag gcatttgggc ttcggcagga attggattag ctattggagt aggtttttat
     7861 gagggagctc ttttagtagc catttctgtt tggggtgtga tatccatgtt ccaaccacta
     7921 aaaaaatatc tgcaaaatcg ttctaaaatg attgaattgt atatagtggt taaatctaca
     7981 gaagcctata atcgtgtatt ggtttattgt gcagaaaatg gtatcagaat gaccgattca
     8041 agaacagcgt ttggagatgt taattctgac agaattgaat actttgatgt tccggacaaa
     8101 aaaatagcgt catttattac tctggaatta tcaggtagat ttgaacatct tcgactgatg
     8161 gaagaaattg ctaatattgt aggtgttatt tatgtcgaag aaattagctg aaatttagta
     8221 aacaaaggga cagatgtttt tgtccttttg ttttttagat gttttaatca tctaattttt
     8281 gagtagattt ttgctcagag gtttttatga aa
//
LOCUS       DAVLBE010000072         8045 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.072, whole genome shotgun sequence.
ACCESSION   DAVLBE010000072 DAVLBE010000000
VERSION     DAVLBE010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8045)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8045)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8045
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.072"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            53..1534
                     /locus_tag="VXB91_001818"
     CDS             53..1534
                     /locus_tag="VXB91_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0471226.1"
                     /translation="MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKD
                     DLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQ
                     AESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSE
                     KYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFME
                     VDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESL
                     FMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEF
                     ILFDQKGNTIRNFQNIFPKFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHL
                     VINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSP
                     YDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
     gene            1896..2897
                     /locus_tag="VXB91_001819"
     CDS             1896..2897
                     /locus_tag="VXB91_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV0471227.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLKKVEQ
                     AIKTLNYIPDYYARGMKKNRTETIAIIVPSIWHPFFSEFAMHVENEVYKRNNKLLLCS
                     INGTNREQDYLEMLRHNKVDGVVAITYSPIEHYLTSGIPFVSIDRTYSDIAIPCVSSD
                     NDAGGREAAKQLISKGCQHLAFVGGHNTTINETKRRRISFEKYVQEHKIPLSIFDLDE
                     KVTDYYGKLESFLEENSSIDGIFTINDFTALDVIEILEKNGKRIPHDVQIIGYDGIKM
                     AGDRDYLLSTIEQPLEEMAKEAVRILFDIIDGKTVNLQTILPVKFVEGKTTKNENKS"
     gene            3048..3965
                     /locus_tag="VXB91_001820"
     CDS             3048..3965
                     /locus_tag="VXB91_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001084977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0471228.1"
                     /translation="MNSKAKQVSLWERIKKQKLLLLMTVPGLVLTFIFKYIPMYGVLI
                     AFKDYNPLKGILGSDWIGFSEFTKFISSPNFGILLANTLKLSIYGLLLGFLPPIILAI
                     MLNQLLSEKVKKRIQLILYAPNFISVVVIVGMIFLFFSVGGPINNFLSMFGMKADFLT
                     NPDFFRPLYIFSGIWQGMGWASTLYTATLVNVDPALVEAVRLDGANIFQRIWHIDIPA
                     LKPIMVIQFVLAAGGIMNVGYEKAFLMQTSLNLPTSEIISTYVYKVGLVSGDYSYSTA
                     VGLFNAVINVVLLVAVNQIVKRMNNGEGI"
     gene            3976..4866
                     /locus_tag="VXB91_001821"
     CDS             3976..4866
                     /locus_tag="VXB91_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV0471229.1"
                     /translation="MKNSIMDTKFDRRILLLNKIIIVFIVLMTLLPLLYIVVASFMDP
                     KVLVSRGISFNPADWTVEGYQRVFSDQSILRGFINSLLYSFGFAALTVLLSVFTAYPL
                     SKKDLVGRRWINYFLIVTMFFGGGLVPTYLLVKELGMLNTPWAIIVPGAVNVWNIILA
                     RAYFQGLPEELVEAAVIDGANDLQIFFKIMLPLAKPIMFVLFLYAFVGQWNSYFDAMI
                     YIKDPNLEPLQLVLRKILIQSQPGQDMIGAQAAMNEMKRLAELIKYATIVISSLPLIV
                     MYPFFQKYFDKGIMAGSLKG"
     gene            4895..6511
                     /locus_tag="VXB91_001822"
     CDS             4895..6511
                     /locus_tag="VXB91_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV0471230.1"
                     /translation="MKFKTFSKSAVLLTASLAVLAACGSKNTASSPDYKLEGVTFPLQ
                     EKKTLKFMTASSPLSPKDPNEKLILQRLEKETGVHIDWTNYQSDFAEKRNLDISSGDL
                     PDAIHNDGASDVDLMNWAKKGVIIPVENLIDKYMPNLKKILDEKPEYKALMTAPDGHI
                     YSFPWIEELGDGKESIHSVNDMAWINKDWLKKLGLEMPKTTDDLIKVLEAFKNGDPNG
                     NGEADEIPFSFISGNGNEDFKFLFAAFGIGDNDDHLVVGNDGKVDFTADNDNYKEGVK
                     FIRQLQEKGLIDKEAFEHDWNSYIAKGHDQKFGVYFTWDKNNVTGSNESYDVLPVLAG
                     PSGQKHVARTNGMGFARDKMVITSVNKNLELTAKWIDAQYAPLQSVQNNWGTYGDDKQ
                     QNIFELDQASNSLKHLPLNGTAPAELRQKTEVGGPLAILDSYYGKVTTMPDDAKWRLD
                     LIKEYYVPYMSNDNNYPRVFMTQEDLDKIAHIEADMNDYIYRKRAEWIVNGNIDTEWD
                     DYKKELEKYGLSDYLAIKQKYYDQYQANKN"
     gene            6521..7840
                     /locus_tag="VXB91_001823"
     CDS             6521..7840
                     /locus_tag="VXB91_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEV0471231.1"
                     /translation="MGDKKYTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEETGVRQVQNMAFSDDGIHFEKIEQNPVATGSDLPDELIA
                     ADFRDPKLFEKDGRYYSVVAAKHKNNVGCIVLLGSDNLVEWQFESIFLKGVEHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWGEKCFIPESVQEIDH
                     GQDFYAPQTLLDDQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDIDYLEFGYDSNAQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
BASE COUNT         2701 a         1265 c         1530 g         2549 t
ORIGIN      
        1 gtataattgc aagaggttta atccgataat ttataaagag agaaagatat tcatgagaga
       61 tttattatct aaaaaaagtc ataggcaatt agaattatta gaattattat ttgaacataa
      121 acgttggttt catcgttctg aactagcaga gttattaaat tgtacagaac gtgcagtcaa
      181 agatgatcta tcccatgtta aatctgcttt tcctgacttg atttttcatt cttctactaa
      241 tggtatacgc attattaata ccgatgatag tgatattgaa atggtttacc atcatttctt
      301 taaacattca actcattttt cgattttaga attcatcttc tttaatgaag gttgtcaagc
      361 tgagagtatt tgtaaagaat tttatatcag ttcatcttcg ctctatcgta ttattagcca
      421 aatcaataaa gtgattaaaa ggcaatttca atttgaagtc agtctgaccc ctgttcaaat
      481 cattggaaat gagagagaca ttcgttactt ttttgcacaa tatttttcag aaaaatatta
      541 tttcctagaa tggccatttg aaaatttttc atcagagcca ctatctcaat tgttagaatt
      601 ggtttataag gaaacaagct ttccaatgaa tttgtcaacg catagaatgc taaagttgct
      661 cctagttacg aacctatata gaataaagtt tggtcatttt atggaagtag ataaagattc
      721 ttttaacgac caaagtttgg attttttaat gcaggcagaa ggaatagaag gtgttgctca
      781 gagttttgaa tcagaataca atatctcttt agatgaagaa gttgtttgcc aattatttgt
      841 gtcttacttt caaaaaatgt ttttcataga tgaaagtctc tttatgaaat gcgtaaaaaa
      901 ggatagttat gttgaaaaat cttaccatct attgagtgat tttattgatc agatttcagt
      961 caagtatcag attgaaatgg agaataagga taatctgatt tggcatctgc ataataccgc
     1021 acatctgtat cgtcaagagt tgtttactga gtttatttta tttgatcaaa aagggaatac
     1081 aatcaggaac tttcaaaata tttttccaaa atttgtttca gatataaaaa aagagctttc
     1141 tcactattta gagactcttg aggtttgttc tagttcaatg atggtaaatc atctatctta
     1201 taccttcatc actcatacca aacatttggt gattaatttg ctacaaaatc agcctaaact
     1261 aaaggtttta gttatgagta attttgatca gtatcatgca aaattcgttg cagagacact
     1321 ttcttattac tgtagcaata attttgaact ggaagtttgg actgaattag aattatcaaa
     1381 ggaatcttta gaagattcac cttatgatat cattatttct aattttatta ttcctcctat
     1441 tgaaaataag agactcatct attcaaataa tataaacacg gtctcactca tatacttgtt
     1501 aaatgccatg atgtttattc gattagatga gtaaccaaaa ataacaaaaa aacgctattt
     1561 cgcgtttgaa ctgtacctca aaagttagac agaaaaaatc taatttttgg ggtgtttttg
     1621 ttaagaaaag accttcaatc atttaagcaa aatgtacatc tagatttata gccctctaaa
     1681 actcttgctt tttttgtaga agatacgaaa aaagccataa aaccaaggct tttcctgttt
     1741 tatgtagatg tttacacatg aaaattgaag tattttcaaa agctaattgg agtgatttta
     1801 ttcatgatgg gataaatgat ctggccaaaa atgattgaga aatagttgct taaaaagcat
     1861 ttgcatgata ctatatattg aaaggaggtg ataatatggt agaacaaaga aaatcaatta
     1921 ccatgaaaga tgttgcttta gaagcaggag ttagtgttgg aactgtttca cgtgtaatta
     1981 ataaagaaaa aggcattaaa gaagtaactt tgaaaaaagt ggaacaagcg attaaaactt
     2041 tgaattacat tccagattac tatgctagag gaatgaaaaa aaatcgaaca gaaacgattg
     2101 caatcattgt accaagtatc tggcatccct tcttttcaga atttgctatg catgtggaaa
     2161 atgaagtcta taagagaaat aacaaattac tcttatgttc tataaatggt acaaatagag
     2221 agcaagacta tctggagatg ttgcgtcata ataaagttga tggagtggtt gccattacct
     2281 atagtccaat tgaacattac ttgacgtcag gaattccctt tgttagtatt gaccgcacat
     2341 actcagatat tgccattcct tgtgtttcat cagataatga tgcaggtgga agagaagcag
     2401 ctaaacaatt aattagtaaa ggatgtcagc atttagcctt tgtgggcgga cataatacaa
     2461 ccattaatga aaccaaacgt cgtagaattt catttgaaaa gtatgtccaa gagcataaaa
     2521 tacctcttag tatttttgat ttggatgaga aagttactga ctattatgga aagctagaga
     2581 gtttcttgga agaaaattct tctatagatg gaatttttac aatcaacgat tttacagctt
     2641 tggatgtgat tgaaatacta gaaaaaaatg gcaaacgtat tcctcatgat gtccaaatta
     2701 ttggatacga tggaattaaa atggctggag atagagatta tctactttca actattgaac
     2761 aaccattgga agaaatggca aaagaagcgg ttcgtatttt gtttgatata attgatggaa
     2821 agactgttaa tttgcagaca atcctaccag taaaatttgt tgaaggaaaa acaacaaaaa
     2881 atgaaaataa gtcttgacag aaagcgctat caatgataga atgaattcag ataaaaagat
     2941 ttatttttaa aacaaaaatg aaacgtttca aaaaaagaaa taaaaagaca gcgccaagcg
     3001 ctatctttta tagaaaaaat gaaacgtttc aaaaaaagga ggttgctatg aatagcaaag
     3061 cgaagcaagt ttctctttgg gaaagaatca agaaacaaaa actcttgtta ttgatgactg
     3121 tccccggttt agttttaacc tttatcttta aatacatccc tatgtatggg gttttaatcg
     3181 catttaaaga ttacaatcct ttaaaaggaa ttttagggag tgattggatt ggtttttctg
     3241 agtttacaaa attcatatcc tctcccaact ttggtatctt gttagccaac acattaaaat
     3301 taagtatcta tggtttattg cttggctttt taccaccaat cattcttgcg attatgctca
     3361 atcaactctt gagtgaaaaa gtcaaaaaac gaattcagct cattttatac gcaccaaact
     3421 ttatctcagt cgttgttatt gtcggtatga ttttcctctt cttttcagtg ggaggaccaa
     3481 tcaacaattt tctttctatg tttggaatga aggctgactt cttgacaaat ccagacttct
     3541 ttagaccctt atacatcttt agtggtatct ggcaaggaat gggctgggct tcaacgctct
     3601 acacggcaac attggtaaat gtagatccag ccttagtaga agcagttcga ctggatggag
     3661 ccaatatctt ccaacgaatc tggcacattg atattccagc tcttaagcct attatggtta
     3721 tccaatttgt tttagctgca ggtggaatta tgaatgtcgg atatgaaaaa gcattcttga
     3781 tgcagacatc gttaaatttg ccaacttctg aaattatctc gacatatgtc tataaagttg
     3841 gtcttgtatc aggagactat tcttactcaa cagcggttgg tttgtttaat gcagtgatta
     3901 acgtagtatt gcttgttgca gttaaccaaa tcgttaaacg catgaataat ggtgaaggaa
     3961 tttaaggagg aaagtatgaa aaattcgatt atggatacaa aatttgatag acgtatctta
     4021 ctcttaaata aaatcattat tgtctttatc gttttgatga ctttgcttcc tttactttat
     4081 atcgtcgtag catcctttat ggatcctaag gttctggtta gtagagggat tagctttaat
     4141 ccagccgatt ggactgtaga aggttaccag cgtgtattca gtgaccaatc tattctaaga
     4201 ggttttatca attctctact atactctttt ggatttgcag ctttaacagt attgctatct
     4261 gtgtttacag cttatcctct ttctaagaaa gacttggttg gacgtcgttg gattaactac
     4321 ttcttgattg tgactatgtt ctttggtggt ggtttagtcc caacttactt gctcgtaaaa
     4381 gaattgggaa tgctcaatac tccatgggct atcattgttc caggtgctgt caatgtttgg
     4441 aatattattc ttgctagggc ctatttccaa ggattgcctg aagaattagt tgaagctgct
     4501 gtcattgatg gagcgaatga cttgcagatt ttctttaaaa tcatgcttcc tcttgcaaaa
     4561 ccaattatgt ttgttctctt cctctatgct tttgtaggac agtggaactc atactttgat
     4621 gcaatgattt atatcaagga tccaaacttg gaaccattgc aacttgtact tcgtaaaatt
     4681 ctcattcaga gccaaccagg tcaagacatg attggagcac aagcggctat gaatgaaatg
     4741 aaacgtttag ctgaattgat taaatacgca actattgtca tttccagctt gccattgatt
     4801 gttatgtatc cattcttcca aaaatacttt gataaaggaa ttatggctgg ttcacttaaa
     4861 ggataaaaaa agaaaaaata aaaggagttt tctcatgaaa ttcaaaacat tctcaaaatc
     4921 agcagttttg ttgacagcta gtttagcagt acttgcagcc tgtggctcaa aaaatacagc
     4981 ttcaagtcca gattataagt tggaaggtgt aacattcccg cttcaagaaa agaaaacatt
     5041 gaagtttatg acagccagtt caccgttatc tcctaaagac ccaaatgaaa agttaatttt
     5101 gcaacgtttg gagaaggaaa ctggcgttca tattgactgg accaactacc aatccgactt
     5161 tgcagaaaaa cgtaacttgg atatttctag tggtgattta ccagatgcta tccacaacga
     5221 cggagcttca gatgtggact tgatgaactg ggctaaaaaa ggtgttatta ttccagttga
     5281 aaatttgatt gataaataca tgccaaatct taagaaaatt ttggatgaga aaccagagta
     5341 caaggccttg atgacagcac ctgatgggca catttactca ttcccatgga ttgaagagct
     5401 tggagatggt aaagagtcta ttcacagcgt caacgatatg gcttggatta acaaagattg
     5461 gcttaagaaa cttggtcttg aaatgccaaa aactactgat gatttgatta aagtcctaga
     5521 agctttcaaa aacggggatc caaatggaaa tggagaggct gatgaaattc cattttcatt
     5581 tattagtggt aacggaaacg aagattttaa attcctattt gctgcatttg gtatagggga
     5641 taacgatgat catttagtag taggaaatga tggcaaagtt gatttcacag cagataacga
     5701 taactataaa gaaggtgtca aatttatccg tcaattgcaa gaaaaaggct tgattgataa
     5761 agaagctttc gaacatgatt ggaatagtta cattgctaaa ggtcatgatc agaaatttgg
     5821 tgtttacttt acatgggata agaataatgt tactggaagt aacgaaagtt atgatgtttt
     5881 accagtactt gctggaccaa gtggtcaaaa acacgtagct cgtacaaacg gtatgggatt
     5941 tgcacgtgac aagatggtta ttaccagtgt aaacaaaaac ctagaattga cagctaaatg
     6001 gattgatgca caatacgctc cactccaatc tgtgcaaaat aactggggaa cttacggaga
     6061 tgacaaacaa caaaacattt ttgaattgga tcaagcgtca aatagtctaa aacacttacc
     6121 actaaacgga actgcaccag cagaacttcg tcaaaagact gaagtaggag gaccactagc
     6181 tattctagat tcatactatg gtaaagtaac aaccatgcct gatgatgcca aatggcgttt
     6241 ggatcttatc aaagaatatt atgttcctta catgagcaat gacaataact atccaagagt
     6301 ctttatgaca caggaagatt tggacaagat tgcccatatc gaagcagata tgaatgacta
     6361 tatctaccgt aaacgtgctg aatggattgt aaatggcaat attgatactg agtgggatga
     6421 ttacaagaaa gaacttgaaa aatacggact ttctgattac ctcgctatta aacaaaaata
     6481 ctacgatcaa taccaagcaa acaaaaacta gaggttgatt atgggagata agaaatacac
     6541 agtagaaaaa gccaatcgtt ttatagcaga aaataaacat ctcgttaata ctcaatataa
     6601 gcctgaagaa catttttcag ctgagattgg ttggatcaat gatccaaatg gatttgtcta
     6661 ttttcgtgga gaataccatc tcttttatca attctatcca tatgatagtg tttgggggcc
     6721 tatgcactgg ggacatgcta aaagtaagga cttggtgact tgggagcact tgccagtggc
     6781 acttgctcct gaccaagatt atgaccgaaa tggttgtttc tcaggctctg ccattgtcaa
     6841 ggatgatcgc ctctggctca tgtacactgg acatatcgaa gaagaaaccg gtgtccgcca
     6901 agtgcaaaat atggcatttt cagatgacgg gattcacttt gaaaagattg aacaaaatcc
     6961 agttgcaact ggatcagact tgccagatga gttgattgct gctgattttc gtgatccaaa
     7021 actctttgaa aaagatggac gctattactc cgtagtagct gccaaacaca agaataatgt
     7081 gggctgtatc gttctactag ggtccgataa cctagtagaa tggcagttcg aatccatctt
     7141 tttaaaaggg gtagaacacc aaggctttat gtgggaatgc ccagattact tcgagttaga
     7201 tgggaaagat tgccttatta tgtcacccat gcgttatcag cgtgagggag actcatatca
     7261 taacatcaac tcatcgcttt tgttcacggg taaggtagat tggggagaaa aatgttttat
     7321 cccagaatca gttcaagaaa ttgatcatgg ccaagacttc tatgcgcctc aaacattgtt
     7381 ggacgatcaa aatcgtcgta tcctgattgc ttggatgcag acatgggggc gtacccttcc
     7441 aacccatgac caagaacaca aatgggcatg tgccatgact ttacctagaa ttttaagatt
     7501 ggaagatggc aaactaagac aattccctgt taaaaaaggc caatatcaaa tccaaataga
     7561 taaagattgt cattaccact taggaaatga tatagattat cttgaatttg gttatgatag
     7621 taatgcgcag caagtttaca ttgatcgtag ccatcttatt caaaaaattc taggtgaaga
     7681 agaacaggac actagtcgac ggtatgtaga tattgaagct aaagaattgg aagttgttct
     7741 agataaaaat tccatcgaga tttttgtcaa tcaaggtgaa gcaagcttga ctgcaactta
     7801 ttacttaacg gtgccagctg agctatcacg aattgattaa aaattaagtt atttctccta
     7861 aagaaaaagt tctctttcta aaatagtgga aagaggactt tttgtgtttt gggtatataa
     7921 gcttagttta tggtatttgt aaaattggtg ttggattatg atttaagcta gttttctaaa
     7981 gaatttgaaa aaaattttat ttaagcaaaa aaaacccttg gttccaaggc ttttcctgtt
     8041 gtatt
//
LOCUS       DAVLBE010000073         7851 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.073, whole genome shotgun sequence.
ACCESSION   DAVLBE010000073 DAVLBE010000000
VERSION     DAVLBE010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7851)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7851)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7851
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.073"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(16..204)
                     /locus_tag="VXB91_001824"
     CDS             complement(16..204)
                     /locus_tag="VXB91_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001828711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="blpT protein"
                     /protein_id="HEV0471232.1"
                     /translation="MLYYRERVHQIKEDAHMEDKKLIQLLSKLNKSYQNCKQVTADDI
                     RLQELLNTTMQELKKQKS"
     gene            325..867
                     /locus_tag="VXB91_001825"
     CDS             325..867
                     /locus_tag="VXB91_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HEV0471233.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVDDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNQLDQEVLDDD
                     LVLPIENGALDLAESVSDNILLNIPIKVLTAEEEAGQGFVSGNDWQIMTEEEYQAQQA
                     VKKEENSPFAGLQGLFDGDE"
     gene            867..1496
                     /gene="nth"
                     /locus_tag="VXB91_001826"
     CDS             867..1496
                     /gene="nth"
                     /locus_tag="VXB91_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HEV0471234.1"
                     /translation="MVLSKKRARKVLEEIIALFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            1707..2228
                     /gene="pyrR"
                     /locus_tag="VXB91_001827"
     CDS             1707..2228
                     /gene="pyrR"
                     /locus_tag="VXB91_001827"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HEV0471235.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            2247..3170
                     /locus_tag="VXB91_001828"
     CDS             2247..3170
                     /locus_tag="VXB91_001828"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HEV0471236.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGAELFFAGPEEWRSQEFADYGQFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            3220..4299
                     /gene="carA"
                     /locus_tag="VXB91_001829"
     CDS             3220..4299
                     /gene="carA"
                     /locus_tag="VXB91_001829"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HEV0471237.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            4611..7787
                     /gene="carB"
                     /locus_tag="VXB91_001830"
     CDS             4611..7787
                     /gene="carB"
                     /locus_tag="VXB91_001830"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HEV0471238.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKERPDALLPTLGGQTGLNMAMEL
                     SKNGILDELGVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVHHNEIPELAAVSDDALIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDQVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIRSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKDVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
BASE COUNT         2283 a         1592 c         1767 g         2209 t
ORIGIN      
        1 ttaagatact gttgttcaac ttttctgttt tttgagctct tgcatagtag tgtttagcag
       61 ctcttgtagt cgaatatcat ctgccgtaac ctgtttacag ttttggtagc ttttatttaa
      121 cttggatagg agttgaatga gtttcttgtc ttccatgtga gcatcctcct tgatctgatg
      181 tactctttcc ctatagtata gcactaaaaa ataaaactat catagtaaat atgttaaaat
      241 ttgaatttta attacaaagt ttggtgtgct gatttgtagc cttttcatgg tataatcaag
      301 agagtaaatc tttatggagg aagtatgaaa ttaaatattc aagaaattcg taagcagtct
      361 gaaggtttga actttgaaca aacgttagat ttagttgatg acctgcgtgc acgtaatcaa
      421 gaaattttag atgtaaaaga tatccttgca gttgggaaag tacaatatga agaccgtatg
      481 tatttcttag attatcaact atcttatacc attgttcttg cttcgagtcg cagtatggag
      541 ccagttgagt tagttgaatc ttatccagtc acggaagttt tcatggaagg cgcaactaac
      601 cagctagatc aagaagtttt agatgatgac ttggtcttgc ccatcgaaaa tggggcgctt
      661 gaccttgctg agagtgtatc agacaatatc ctgctaaaca ttcctatcaa ggtcttgacg
      721 gctgaagaag aagctggtca aggatttgtc tcaggaaatg actggcaaat catgacagag
      781 gaagaatacc aagctcaaca agcagtaaag aaagaagaaa acagtccttt tgctggctta
      841 caaggactat ttgacggaga tgaataatgg tcttgtcaaa aaaacgagca cgaaaggtgc
      901 tagaagaaat cattgccctc ttcccagatg ccaagcctag tcttgatttt accaatcatt
      961 ttgaactcct ggttgcggtc atgttatcag cccagacgac agatgcagcg gtaaataagg
     1021 ccacaccagg tctctttgtt gcctttccaa caccccaagc tatgtctgta gcgacagaga
     1081 gtgagattgc ttcacatatt tctcgcttgg gattgtatcg gaataaagct aaattcctta
     1141 aaaaatgtgc ccaacagtta ctagacgatt ttgatggtca agtccctcag acacgtgaag
     1201 aattggagag tttggcaggt gttggtcgca agacagccaa tgttgtcatg agtgtaggat
     1261 ttgggattcc agcctttgca gtggatactc atgtggagcg tatttgcaaa caccacgata
     1321 ttgtcaaaaa atcagcgacg ccacttgagg tggaaaagcg ggtcatggat atcttgccgc
     1381 ctgagcagtg gttagctgcc catcaggcca tgatttattt tggaagagcc atttgccatc
     1441 caaaaaatcc agagtgtgac cagtacccac aattatatga ttttagcaat ttgtaagatg
     1501 ctacattgaa actttttgct tgattttaag catgctttgt gctatagtaa atgataacta
     1561 aatattcctt taaacctgtc ccgtgaggca ggcaaggagc gcgataaagt agaagggtga
     1621 agtctacact gtgtgcagta gggctcgctt ggctataaat ttcaagtctc cttgtttaag
     1681 gagacttttc tttttggagg tttgtcatga aaacaaaaga agttgtagac gaattgaccg
     1741 tcaaacgagc gattacgcgt attacttatg agattatcga acgcaacaaa gatttgaata
     1801 agatcgtctt ggctggtatt aaaactcgtg gtgtctttat tgcccaccga atccaagaac
     1861 gtttgaagca gttagaaaat ctttcagttc ctgttgtgga attggatact aaacctttcc
     1921 gtgatgatgt taaaagtgga gaagatactt ctttggtttc tgtcgatgtg acagaccgcg
     1981 aagttatctt ggtggatgat gtgctctata caggtcgtac catccgtgct gctattgata
     2041 atattgtcgg tcatggtcgt cctgcgcgtg tgagtttagc agttctagtc gatcgtggac
     2101 atagagaatt gccaatccgt ccagattacg ttggaaaaaa tatcccaacc agtcgttctg
     2161 aagaaatcat cgtagagatg acagaacttg atgaccaaga cagagttctg attactgaag
     2221 aagcttagaa agttaaagga gtagccatgt cagaaaatca acaagcattg aaccatgtgg
     2281 tgtccatgga agacctcact gtcgatcaag taatgaaatt gatcaagcga ggaattgagt
     2341 ttaaaaatgg agcccagctt ccctatgaag accatccgat tgtttccaat ctcttctttg
     2401 aggattctac acggacacat aagtcctttg aagtcgcaga gattaaactt ggattggaac
     2461 gacttgactt tgatgtgaag actagttcgg ttaataaggg tgagacactt tatgacacca
     2521 ttttgactct gtctgcttta ggagtggatg tctgtgtgat tcgccatcca gaggtcgact
     2581 actatagaga attgattgct agtccaacga ttacgacttc catcatcaat ggtggagatg
     2641 gttcgggcca acaccctagc cagagcttgc ttgatttgat gaccatttat gaggaatttg
     2701 gccactttga gggtcttaaa gttgctattg caggtgactt ggatcactca cgcgttgcca
     2761 aatccaatat gcagattttg aaacgcttgg gagctgaact ctttttcgct ggacctgagg
     2821 aatggagaag tcaagagttt gcagactatg gacagtttgt aaccattgat gaaatcattg
     2881 atcaggttga tgtcatgatg tttctccgtg tgcaacacga acgccatgat agtggagctg
     2941 tattttcaaa agaagactac catgcccaac atggcttgac tcaagaacgt tacgatcgtt
     3001 tgaaagaaac agcaatcctc atgcacccag ctccaatcaa tcgtgatgta gaaatagcag
     3061 accacttggt tgaagcacca aaatcacgga ttgtccaaca aatgaccaat ggtgtctttg
     3121 ttcgaatggc aatcttagaa tccgtactag cgagtagaaa cgccaactaa aacacaagac
     3181 gttaaaagac gccagtgagc gtccacgaga ggtgaaaata tgacaaaaag aattctagta
     3241 ttagaagatg gcacagtttt tgaaggcaag gccttcggag cagatattga tgtaacaggc
     3301 gaaatcgtct ttaatacagg gatgaccggc taccaagaat ccattacaga ccagtcttat
     3361 aatggacaaa tcttgacctt tacttatcct ttggtaggaa attatggtat taatcgtgat
     3421 gattatgaat ccattattcc aacttgtaag ggagtcgttg tttttgaaga agcgcgtaga
     3481 gctagcaact ggcgcaacca aatgaccttg gatgaatttt tgaaagccaa gaaaattcca
     3541 gggatttcag gaattgatac gcgtgctctt accaagatta tccgtaagca tggtactatg
     3601 cgtgcaacct tgacccatgt tggggacagt atggaccatg tgacggacca gctccaagca
     3661 acagttttac cgacagacaa tatcaaacag gtttctacta aaacgtctta tccagctcca
     3721 ggagttggtt tgagcgtggt gctagtggac tttggtctca agcactcaat cctacgtgaa
     3781 ctttctaaac gcaactgtaa cgtgacagtt gttccttatt cgacaacggc tgaagaaatt
     3841 ctccatctca atcctgatgg agttatgttg tcaaatggtc caggtaaccc agaagacgtt
     3901 ccacaagcac tcgacatgat tcgcggtgta caaggaaaaa ttccaatctt tggtatttgt
     3961 atgggacacc aactctttgc aatggcaaac ggggctaaga cctataagat gaagtttggc
     4021 catcgtggat tcaaccatgc ggtacgtgaa atcgcaacag gacgagtaga cttcaccagc
     4081 cagaaccatg gttatgcagt cagccgcgag gatttgccag agcacttgat tattacccac
     4141 gaagaaatca atgacaagtc agtggaaggt gtgcgccaca gataccaacc tgctttctct
     4201 gttcaatacc acccagatgc agctcctggg ccacacgacg ctagctacct atttgacgag
     4261 tttatcgaga tgatggaagt ttttaaacaa tcaaactaag aacgagtaaa agctcgtcgg
     4321 agaatttatg taactgaaca cggacggaaa gctcagaatt tagagaaacc aacttggatt
     4381 gtcaatcctt ccttgatttc ttaaaattca atcgctttct attcgtcctt tgtatcttat
     4441 ttaatgtcgc cctgagaggc gacgaataga aaggagaaga tacattgttc gcggaagtga
     4501 acacgcccta agaactgtgt gaaaaagata aacatcgtct tgacgctgaa ggcgtctgcg
     4561 ccgagtttcc tattttcact gtgttcttta cgggctttgt atcataaact atgcctaaac
     4621 gtactgatat tcaaaaaatt atggtgattg gttctggtcc gattattatt ggtcaggctg
     4681 ctgagtttga ctacgctggg acccaggctt gcttgtcgtt gaaagaggaa ggttatgagg
     4741 ttgttttggt taactcaaat cctgcaacca tcatgacgga caaggaaatt gctgacaagg
     4801 tttacattga accgattaca cttgagtttg tgacacgtat tcttcgtaag gaacgtccag
     4861 atgccttgct accaacactc ggtggtcaga caggtctcaa catggccatg gaattatcta
     4921 aaaatggtat cctagacgag cttggcgttg aacttctggg taccaaatta tctgccattg
     4981 accaagcgga ggaccgtgac ctctttaaac aattgatgga agagcttgag caacccattc
     5041 cagaatctga aattgttaac acagtagaag aagcagttgc ctttgcagcg acaattggct
     5101 acccagtcat cgttcgtcca gcctttaccc ttggtggtac tggtggtggt atgtgtgcca
     5161 acgaaaaaga attgcgtgaa atcactgaaa atggtttgaa attgtcacct gttacccaat
     5221 gtttgattga gcgttcgatt gccggtttta aggaaattga atacgaagtg atgcgtgact
     5281 cagctgacaa tgccttggtt gtttgtaaca tggaaaactt tgacccagtt gggattcaca
     5341 caggggattc cattgtattt gcccctgcgc aaaccatgtc agactatgaa aaccaaatgc
     5401 ttcgtgatgc gagcttgagc attattcgcg ccctcaagat tgaaggtgga tgtaatgttc
     5461 agctagctct tgatcctaac agcttcaagt attatgttat cgaagtaaac cctcgtgtat
     5521 cacgttcgtc agcccttgct tctaaagcga caggatatcc gattgctaag ttggctgcca
     5581 agattgcagt aggtttgacc ttggatgagg ttataaaccc agttacaggt tcaacctatg
     5641 ccatgtttga accagccctt gactacgtag ttgctaagat tccacgtttc ccatttgaca
     5701 agtttgaaaa gggtgaacgc cgtctcggta cacaaatgaa ggcgactgga gaagtcatgg
     5761 caatcggtcg taacatcgag gaatctcttc tcaaggcctg ccgctccctt gaaattgggg
     5821 tgcaccacaa tgaaatacct gaacttgcag cagtttctga tgatgccttg attgaaaagg
     5881 ttgtcaaagc ccaagatgac cgtctcttct acgtatcaga agccattcgt cgtggctaca
     5941 cacctgaaga aattgcagag cttacaaaaa ttgatatctt ctatcttgat aaactcttgc
     6001 atatctttga aattgagcaa gaattgggtg ctcatccaca agatctagaa gttttgaaaa
     6061 cagccaaact taatggtttc tcagaccgta agattgctga actctgggga acgactgatg
     6121 atcaagttcg ccaacttcgc ttggaaaaca agattgttcc agtttataag atggtagata
     6181 cttgtgcggc agagttcgac tctgaaacgc catatttcta ttcaacctat ggttgggaaa
     6241 atgaatctat cagatctgat aaagaatctg tacttgtcct aggttcaggt ccaatccgta
     6301 tcggtcaagg ggttgagttt gactacgcaa ccgttcactc tgttaaggct atccaggcag
     6361 ctggttatga agctatcatc atgaactcaa acccagagac cgtttcaaca gacttctctg
     6421 tatcagataa gctttacttt gagccattga cattcgaaga tgttatgaac gtcattgact
     6481 tggaacaacc aaagggagtt atcgttcagt ttggtggtca aacagccatc aaccttgcgg
     6541 agccattggc aaaagcaggt gtgaccatcc ttggtacaca ggttgctgac ctagaccgtg
     6601 ccgaagaccg tgacctcttc gagcaagctc tcaaagaatt ggatattcca cagccaccag
     6661 gacaaacggc taccaatgaa gaagaagcag ctcttgcagc tcgtaagatt ggcttcccag
     6721 ttcttgtccg cccatcttat gtacttggtg gacgtgccat ggaaatcgtt gaaaacgaag
     6781 aagaccttcg ttcttacatg cgaactgctg ttaaggctag tccagatcac ccagttcttg
     6841 tcgactctta tatcgttggg caagagtgcg aagttgatgc catttcagat ggtaaagatg
     6901 tgctcattcc tggtatcatg gagcatatcg aacgtgctgg tgtccactca ggtgactcaa
     6961 tggctgttta cccaccacaa accttgtcgc aaaaggttca ggagaccatc gcagactaca
     7021 ccaaacgctt agcaatcggt cttcactgcc ttggaatgat gaacatccag tttgttatca
     7081 aggatgaaaa agtctacgtt attgaggtca atccacgtgc cagccgtact gttccattcc
     7141 tatctaaggt aaccaatatt cctatggctc aagtagcgac caagctcatt cttggtcaaa
     7201 gtttatcaga acttggctac caaaatggac tttaccctga aagcacccgt gttcatatca
     7261 aggcacctgt cttctccttt accaaactag ctaaggtaga cagcttgctc ggtcctgaaa
     7321 tgaagtcaac aggtgaagtt atgggttctg atgctacttt ggaaaaagct ctctataaag
     7381 cctttgaagc ttcttatcta cacttgccaa cttttggtaa tgtcgtcttt accatcgctg
     7441 atgatgccaa agaagaagcc ttgaacttgg ctcgtcgttt ccaaaacatt ggttatggaa
     7501 tccttgcgac agaagggaca gcagccttct ttgctagtca tggcttgcaa gcccaacctg
     7561 ttggtaagat tggtgatgac gataaggata tcccaagttt tgtacgcaaa ggaagaattc
     7621 aagctatcat taacacagta ggaacaaaac gaactgctga cgaagatggt gagcaaattc
     7681 gtcgttcagc cattgaacac ggggtgcccc tcttcacagc gctagataca gctaatgcca
     7741 tgcttaaggt acttgaaagt cgtagctttg ttacagaagc gatttaaata gaaaaataag
     7801 atatagcaga ctgaatttag aacagtacac aggaatacta aaatatttct a
//
LOCUS       DAVLBE010000074         7777 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.074, whole genome shotgun sequence.
ACCESSION   DAVLBE010000074 DAVLBE010000000
VERSION     DAVLBE010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7777)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7777)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7777
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.074"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(145..441)
                     /locus_tag="VXB91_001831"
     CDS             complement(145..441)
                     /locus_tag="VXB91_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uberolysin/carnocyclin family circular
                     bacteriocin"
                     /protein_id="HEV0471239.1"
                     /translation="MKSKRMEFHNKFLIVSAMLAVISWLSLGVVSFPMLAGTLGISTK
                     AAATVVNLISAYSTVTAVISIVGAITGVGSIGSGIAATVLYILKKKGAAKAALW"
     gene            complement(984..1877)
                     /locus_tag="VXB91_001832"
     CDS             complement(984..1877)
                     /locus_tag="VXB91_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0471240.1"
                     /translation="MDELKREIGYKIKTIRRSCGKTQIDICGDESELTIRQLARIENG
                     QALATLPKLLLIADKLGVSLQNIVDVKVIEIPKGFLKLKDELIHSQTYADKGRIERKE
                     AILEEIYENYYENLPEEEQLIVDVTQARFDIYGSSDVTYGLGLVEEYFQQLLKKKYFS
                     VNDLLIIELYFFCCAMGLEDKEHFEELAQKVLLCSEYEDKASLVQMEKVLLSLFIQIQ
                     TEDSLIYIQTFEKIIAKTRHVFYRPHLFLLKAKYALFVDKNILEAESFYEKAISLAEL
                     LDDQVLVQRILAEKQIDFPTT"
     gene            complement(2628..2858)
                     /gene="blpU"
                     /locus_tag="VXB91_001833"
     CDS             complement(2628..2858)
                     /gene="blpU"
                     /locus_tag="VXB91_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HEV0471241.1"
                     /translation="MNTKKMSQFEIMDTEMLACVEGGGCNWGDFAKAGVGGGAVRGLQ
                     LGIKTRTWQGAATGAAGGAILGGVAYAATCWW"
     gene            complement(3061..3351)
                     /locus_tag="VXB91_001834"
                     /pseudo
     CDS             complement(3061..3351)
                     /locus_tag="VXB91_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(3397..3630)
                     /locus_tag="VXB91_001835"
     CDS             complement(3397..3630)
                     /locus_tag="VXB91_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEV0471242.1"
                     /translation="MTEKEIFDRIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQNVGDVVKIIQGK"
     gene            complement(3636..4628)
                     /gene="plsX"
                     /locus_tag="VXB91_001836"
     CDS             complement(3636..4628)
                     /gene="plsX"
                     /locus_tag="VXB91_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HEV0471243.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLAADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRAKLGALLLKDSLSGLKKQLN
                     YSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE"
     gene            complement(4625..5395)
                     /gene="recO"
                     /locus_tag="VXB91_001837"
     CDS             complement(4625..5395)
                     /gene="recO"
                     /locus_tag="VXB91_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HEV0471244.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKRMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDKRRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            complement(5392..6561)
                     /locus_tag="VXB91_001838"
     CDS             complement(5392..6561)
                     /locus_tag="VXB91_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV0471245.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQVISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKAVILNYPANPTGITYSREQLEALAAVLRKYEIFVVCDEVYSELTYTGEAH
                     VSLGTMLRDQAIIINGLSKSHAMTGWRLGLIFAPATFTAQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            6710..7720
                     /locus_tag="VXB91_001839"
     CDS             6710..7720
                     /locus_tag="VXB91_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family protein"
                     /protein_id="HEV0471246.1"
                     /translation="MSFLSKNGAGILACLLISILSWYLGGFFPVIGAPVFAIFIGMLL
                     HPFLSSYKQLDAGLTFSSKKLLQYAVVLLGFGLNISQVFAVGQSSLPVILSTISIALI
                     IAYLFQRFFALDTKLATLVGVGSSICGGSAIAATAPVIHAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNEGFALFAGTAVNDTSSVTAAASAWDSLYQSNTLESATIVKLT
                     RTLAIIPITLFLSYWQSRQQENKQSLQLKKVFPLFILYFILASLLTTLLTSLGVSSSF
                     FTPLKQLSKFLIVMAMSAIGLKTNLVAMVKSSGKSIVLGAICWIAIILTTLGMQTLIG
                     IF"
BASE COUNT         2258 a         1809 c         1234 g         2476 t
ORIGIN      
        1 aaataatttc ccttgaaaag gaagatagct tttaaaatag attgacaaac ttatgataac
       61 aaaaaacaaa agggttatcc caataaaatt aagataacct aaaatacttt cacattcttt
      121 tttagaaagt attttcatct agttctacca tagagctgct ttagcagcac ctttcttttt
      181 caatatataa agaactgttg ctgcaatacc cgaaccaata gaacctactc ctgtgattgc
      241 acctacaatt gaaattactg ctgtaactgt actataagca ctaatcaaat tgactacagt
      301 agcagcagct tttgtcgaaa ttcctaatgt cccagccaac ataggaaaag aaacaacacc
      361 taagcttaac caactaatga ctgctaacat tgctgaaaca ataagaaatt tattatgaaa
      421 ttccattctt ttagatttca ttttagtgta ctccttttgt atattatgta tgttttattg
      481 agagttaatt cgcacatgtt gtattcctaa ctctcttcaa atgttcgtct atattttata
      541 ctacttttat taacatatct ataataaata aattactact acattttcct agattatcaa
      601 attactttta tatcactaag actcaataaa agataatgtc tatttaactt ttatacgatt
      661 actacctcct ttttagttta cacttcctac atcataaata aacatactca accctcacaa
      721 tctccaaata actcttctat atcattgaaa attgagtttc atcctctata ctaatgtagg
      781 aaacctatta aaacattcct ttaatccaat ataagaatac cttgttccat taatctctac
      841 ccgatattat agatagaacc agactcctat acttaaaagg acaaataacg ttccaaccat
      901 aataaacctc ctttcttttt gagaacgttt tctttatagg tttagtatag caaaaacatg
      961 aaaaaaacaa cctgacttag aagtcaggtt gttgggaaat ctatctgttt ttctgctaaa
     1021 attctctgaa ctaatacctg atcgtctagc aattctgcta gagaaatcgc cttttcatag
     1081 aaactttctg cctctaaaat attcttgtct acaaataaag catattttgc ctttagcaaa
     1141 aatagatgag gtcggtaaaa aacatgtctt gttttagcaa taattttctc aaatgtttga
     1201 atatatatca gactatcttc tgtctgaatt tggataaata ggctcagaag aactttttcc
     1261 atttgaacta ggctagcctt atcttcatat tctgaacata gcaatacttt ttgagctaac
     1321 tcctcaaaat gttctttatc ttctaatccc atagcacaac aaaagaaata caattcaata
     1381 atcaacaaat catttacaga aaaatatttc ttttttaata actgctggaa atattcttcc
     1441 actaacccta aaccgtaggt cacatctgaa ctaccataaa tatcaaaacg agcttgtgtc
     1501 acatccacaa ttaactgctc ttcctcaggc aaattctcat aatagttttc atatatttcc
     1561 tcaagtatag cttcttttcg ttcgattctt cccttatcag cgtaggtttg agaatgaatc
     1621 agctcatctt tgagttttag gaatcctttt ggaatctcta taaccttaac atccacaata
     1681 ttctgtaatg atactccaag tttatccgca atcaataata atttaggaag tgttgctaaa
     1741 gcttgcccat tttcaatacg tgctagctga cgaatcgtca actctgattc atcaccacaa
     1801 atatctatct gagtttttcc acaagatcgc ctaatagttt tgattttata accaatttca
     1861 cgtttcaact catccatagt aatactcctt aagttgatta caaagatttc tttttcttcc
     1921 taattctttt gtcaatcata tataaaacga taagcgaaaa cagcggtaga acaatataac
     1981 tcttttcact cattatcagc tgaaatccca gggttgctag tatcttaaag atgaaaatat
     2041 tcatcaaaaa tagaaaaaca aatactaaaa aatattttaa aaccttcttc atttcttttc
     2101 ttcaactttc ctaatttcta cacctatttt atcgaaaata tatataaaac tccaaataaa
     2161 cacttcgact gcactttttt tggcaaaaaa tagacagaac aaacatccta tctactaaaa
     2221 atatgatatg aaaggaaatt gattttttac tgtcacccta ggcaagcttg aaacaaataa
     2281 atcattgata gtaacactta cgacatccta tttattactt caatttctaa tgtctctgct
     2341 atttctaagc tacctctggt atgatctatt cctagtcaga atagataaca ccgttctaaa
     2401 ttacgattca tagttactcc ttttttgact cgttactata agactcctct ttacatgcgc
     2461 aaaataattt tgattcagat tcatcattta tagttttgat tattttttaa cagatttttc
     2521 tgttttcttc tccgaagact ttaaaaattt ttttctaatt aaatcatcca tataaggacc
     2581 aaatatacca actactaaac caataataaa acttttaaaa tccataatta ccaccaacat
     2641 gtcgctgcat aggccacacc tccaagtata gctcctcccg cagcaccagt tgctgcacct
     2701 tgccatgttc ttgttttaat tcctagctga agacctcgta ctgctcctcc tccaacacct
     2761 gctttggcaa aatctcccca attgcatccg ccaccttcaa cgcaagcaag catctcagta
     2821 tccataattt caaattgtga catctttttt gtattcataa cgaatacctc ttttttattt
     2881 ttaatatttg tcttgttaca aacttgacaa gtttagtata acagtatcta ttaatttttt
     2941 tcatccaaat cttgaattgg catcgaaacg tcttgaatta gcttttttgt ttcaaaatca
     3001 tctctatttt taaaaaagat gttttctaat cactttttta ctattagact tcctgcaaaa
     3061 ctagaatcct agttcatgat tgataatgcc agcaatcaaa ttcattcgta atccgaagtg
     3121 tttacgatga tttcgatagg ttgttgaaat cattttaaac gtttttactt tggcaaagat
     3181 gttctcaacc ttgcttctct ccttggatag cgcatggtta taggctttat cttcagctgt
     3241 tagcggcttg agtttgctgg atttacgtgg agtttgtgct tgaagatata tcttcatgag
     3301 cccttgataa ccactgtcag ccaagatttt accagcttgt ccgatatttc tcatttctaa
     3361 aaaccatcta cttccgttga cttggaactc cgattactat tttccttgaa tgattttaac
     3421 cacatctcct acgttttgga gttggtcaat ttcttcatcg ctgatttcga tactaaattc
     3481 atcttccaga gtcaagataa actccatcaa gtcaacagaa tccgcatcca aatcgtcttt
     3541 cagactcaag gattctgtca cgacaaagtc ctctccctgt cgctcttgga taatggtcac
     3601 aatacggtca aaaatttctt tttctgtcat ctcttttatt ctcctgaaaa ttcacgcgca
     3661 gtctgggcaa ccacgtctgt ttctagcatg gtacggatct gacgaatcgt actataaaca
     3721 gccttggcat cgcttgagcc atgagtcttg acaacaggtg ccttaacacc aaacaagacc
     3781 gctccaccaa catctgaata attgagctgt tttttcaaac cactgaggct gtccttgaga
     3841 aggagggcac ctagtttcgc tcgaagacca ccacctgtaa tagctgtctt gagcaagccc
     3901 atgattccca tagctgtccc ttcgatggat ttgagcacag cgtttcccgt gaaaccatct
     3961 gccacaacaa catctgcaac gccattcatc aaatcacgcg cttccacgtt tccgataaag
     4021 ttcaaacttt catcagccgc cagtaattca taagtttcct tacgaagcgg gtcgcccttg
     4081 ctactctctg ttccgttgtt gagcaaacca acgcgtggtt gcgcaatgcc acggacattt
     4141 ttagcataga aggaacctag aaccgcatat tgatggaggt gctgggctgt attttctgca
     4201 ttggcaccaa ggtctagcat gtcaaaacct tttccatcaa cggtaggcaa ggtagacatg
     4261 agtccaggac ggtcgatatt cttgatacga cccacgatga agaatcctgc tgccaacaag
     4321 gcacctgtat tcccagccga aaggacagcg tctgcttcac catctttgac agccttggct
     4381 gccaatacca tactggcatt tttcttattc ctaatagctc tcgtaggttc atcatccgaa
     4441 tcaatcttct catccgtatg gataatgctg acgcgctctg tcgctgtcag atattgcttg
     4501 attttagctt catctccgta aagttgaacc tcgatatctg aaaagtcaga tagggcttga
     4561 ttgacaccct caacaatggc ctgaggtgcg taatcgcccc ccatggcatc tactgcgatt
     4621 tttttcattt cttttcctct tttagtaatt gtccccagtc tgctagggaa tcaataaatt
     4681 tctttgattt taggtgaatc ccaacgtact cttcatatag ttgatccata aattggcgta
     4741 gctcttgctt gattccaggc ttgagcgaaa tggtctccaa agtctcaaaa tcaatagctt
     4801 gaaattgatt gagcagatag gggatattgg gattgagatg acaacgtctc ttatcctcat
     4861 gataatgctc tggacagagg caggctccat atttgaaaga aaagtcaaaa gcctgaccaa
     4921 cccgatggca gaagacacac tcattaaaat tgaggctgat tccaaatcga gtcaaaattt
     4981 gaatttcaaa aatattggtc aaaacctgat aatccaagcc tgcttccatc aactccaaag
     5041 tcttttgcaa aaaagcaaac aagggagcat cctgctgatt gtcctgcaaa ctagcatctg
     5101 caagagctgc cacataggtc gcataggcca tgacaaagag gtcactatta atcttgggaa
     5161 aagtcatgac ctcatgatag tcttcgatgt aactgagtcc gtcatcattg attcgcaaga
     5221 gaaatcgtgc cagcaccaag ggctgaataa caggcgccag cttagactga ccagcgtgtt
     5281 tgacaaaaaa catgcgtttg ccaacctgct ctgtaaaaat tttgacgagc ttgtcatcct
     5341 cacgaaaatt gcgattgtaa agcaccaagc cttgactcgt gatagactga atcatgcttc
     5401 tctcatgtac tcctcaagtc gtttcatggc ttctttgata gtctccatgc tggctgcata
     5461 agataggcgg acgtagcctt ccccgtaacg tccaaaggct gcaccaggga taaaggcaac
     5521 ggccttcttc tgagcaaaat ccttcagaaa agcaaaggag tcttgattgt agcccgctgg
     5581 aattttagca aaaatataga aggcaccgtc tggtttgata atctcaaaac caagagcagt
     5641 cattttttcg atgatatagt cccgacgttg gatatattcc ttcttcatgg gctccgcatc
     5701 gtttttacca gccgtcaagg cttctactgc agcatgttgc gccatggtat ttgcggcagt
     5761 gaccaagtac tggtgactct tgattaactg ggctgtgaag gtcgcaggag cgaaaatcag
     5821 ccccaaacgc caacctgtca tggcatgcga tttagacaaa ccattgataa taatagcctg
     5881 gtctctcaac atcgttccta gagacacatg ggcttcgcct gtgtaggtca attctgagta
     5941 aacctcatca cagacaacaa aaatttcgta cttgcgtaaa acagctgcca aggcctctaa
     6001 ctgctctcga ctgtaggtaa ttcctgtcgg attggctgga tagttgagaa taaccgcctt
     6061 gagcttatca ccctgctcca aaatggcctt ctccaacatc tcaggagtca agacaaaacc
     6121 attttcagtc gtatcaatct caacaatttc tgccccaact aagttaacaa tcggttcata
     6181 gcctggataa gcaggagctg gcaaaagtac cttgtctccc tcttccaaaa tagccgtcaa
     6241 agtcgcagat aaagcctctg tcgccccaat tgtaaccaag atttcatttt caggagcata
     6301 gtccagttgg tacttttcct taacaaagtc actggctgcc tgacgtagag tcagcagacc
     6361 actcatccct gtatagtagg attggttctg atcaatcgct cgcttggccg cctccttgac
     6421 atggtctggc gttgtaaaat caggttcccc caaggtcaaa cgcaagaccc caggaatctc
     6481 cgaaataacc tggtcaaact gacgaatcaa cgaaacttga attttatcta actgtttatt
     6541 aaagcgctta gttaagtcca tagatacctc ctactttcaa aacgtatctc tattatacta
     6601 caaaagcccc ccgaccgcaa aaatacatta gagaatagct ttccactttc tattttactt
     6661 ttcctgttta taggtctata atggtaatag attttatttg gaggttttta tgtcatttct
     6721 atcaaaaaat ggagcaggta tcttggcctg ccttctcatt tccatcctat cttggtactt
     6781 aggaggattc ttccctgtga ttggcgcgcc cgtttttgcc attttcatag gcatgctcct
     6841 acatcccttt ctctcgtcct ataaacaact ggatgctggt ttgaccttta gttccaagaa
     6901 gttgctccaa tatgccgttg tcttgcttgg ttttggtctc aatatctcgc aggtcttcgc
     6961 agttggccaa tcttcactcc ctgtcatcct gtccactatc tcaatagctc tgattattgc
     7021 ctacctcttc cagcgtttct ttgcactgga tacaaaactg gctaccttgg ttggagtagg
     7081 ttcttctatc tgtgggggtt ctgccattgc agcgacagcg cctgttatcc atgctaagga
     7141 aaaggaagta gcccaagcca tttccgttat ctttttcttc aatgtcttgg ctgcgctcat
     7201 ctttccaacc ctcggcacct ggcttcatct atccaatgaa ggcttcgccc tctttgcagg
     7261 gactgcggtc aacgacactt cctctgtaac ggctgccgcc agcgcttggg acagtcttta
     7321 ccaaagcaat accctcgagt ctgcaaccat tgttaaactc acacgtactt tggccattat
     7381 ccctatcacg ctctttctat cctactggca aagtcgccaa caagaaaaca agcaaagcct
     7441 acaactgaaa aaagtcttcc cactttttat cctttacttt atccttgcct ctctcctcac
     7501 tacactactc acctctctag gtgtgtccag tagtttcttt acccctctca aacaactctc
     7561 taaattcctt attgtcatgg ccatgagtgc tatcggtctc aaaaccaatc tggtcgctat
     7621 ggtcaaatcc agtggaaaat ccattgttct tggagccatc tgctggattg ccatcatcct
     7681 caccactctt ggtatgcaga cccttatcgg cattttctaa cactcttcga aaatctcttc
     7741 aaaccacgtc aacgtcgcct tgccgtaggt atatgtt
//
LOCUS       DAVLBE010000075         7175 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.075, whole genome shotgun sequence.
ACCESSION   DAVLBE010000075 DAVLBE010000000
VERSION     DAVLBE010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7175)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7175)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7175
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.075"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(54..479)
                     /locus_tag="VXB91_001840"
                     /pseudo
     CDS             complement(54..479)
                     /locus_tag="VXB91_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007897432.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(555..767)
                     /locus_tag="VXB91_001841"
     CDS             complement(555..767)
                     /locus_tag="VXB91_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001827253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0471247.1"
                     /translation="MIQPLLHADETSYRVLENDSHLTYYWTFLSGKAENQAITLYHHD
                     QRRSGSVVQEFLGDYSGYVHCDMLRQ"
     gene            complement(776..1081)
                     /locus_tag="VXB91_001842"
     CDS             complement(776..1081)
                     /locus_tag="VXB91_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000484476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase zinc-finger binding
                     domain-containing protein"
                     /protein_id="HEV0471248.1"
                     /translation="MFPVETEEITYKRKKSKGKRQAILAQFDSEEVHHQVEESICPDC
                     QDDLKEIGASLQRQELVFIPAQLKRVDHIQHAYKCQTCSKNNPSDKIVKAPIPKAPL"
     gene            complement(1068..1262)
                     /locus_tag="VXB91_001843"
     CDS             complement(1068..1262)
                     /locus_tag="VXB91_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0471249.1"
                     /translation="MKIIQQQSAIIDSLTNELSLLCEQVAYLTQKLSGKSSEKSVCPF
                     GQLNLFEEESPSEKDGDVPS"
     gene            complement(1432..1782)
                     /gene="tnpB"
                     /locus_tag="VXB91_001844"
     CDS             complement(1432..1782)
                     /gene="tnpB"
                     /locus_tag="VXB91_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEV0471250.1"
                     /translation="MTIHLSSLGQVYLVCGKTDMRQGIDSLAYLVKTHFELDPFSGQV
                     FLFCGGRKDRFKALYWDGQGFWLLYKRFENGRLTWPSTEKDVKALTPEQVDWLMKGFS
                     ITPKINLSESRDFY"
     gene            complement(1763..1948)
                     /locus_tag="VXB91_001845"
                     /pseudo
     CDS             complement(1763..1948)
                     /locus_tag="VXB91_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136123.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(2252..3814)
                     /gene="guaA"
                     /locus_tag="VXB91_001846"
     CDS             complement(2252..3814)
                     /gene="guaA"
                     /locus_tag="VXB91_001846"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HEV0471251.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIREIGVFSELKSHK
                     ISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CLYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            3956..4654
                     /locus_tag="VXB91_001847"
     CDS             3956..4654
                     /locus_tag="VXB91_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV0471252.1"
                     /translation="MLPAYMKIHDQIKKDIDEHRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERRVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKHGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQVSYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(4697..5593)
                     /locus_tag="VXB91_001848"
     CDS             complement(4697..5593)
                     /locus_tag="VXB91_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEV0471253.1"
                     /translation="MSNSLKGTLLTVVAGIAWGLSGTSGQYLMAHGISALVLTNLRLL
                     IAGGILMLLAYATAKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIIFAIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSALTYALYIILPIALIKKWGSSLVIGVGMVIAGLVALPFTGVLQADIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAVFFAFLIMNEQFYPIDF
                     IGMAMILFAVTLISLKDLFLEK"
     gene            complement(5602..6537)
                     /locus_tag="VXB91_001849"
     CDS             complement(5602..6537)
                     /locus_tag="VXB91_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HEV0471254.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSDPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKFGPVELAVPTVRGVEAGIVHDPKARLLGRHAGSAGLFSTI
                     KDLQIFLEHYLADDFARDLNQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(6534..>7175)
                     /locus_tag="VXB91_001850"
     CDS             complement(6534..>7175)
                     /locus_tag="VXB91_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proteinase"
                     /protein_id="HEV0471255.1"
                     /translation="LGMKALLEESAFLSLGDQTGLEKLVLEEAPSMRTRKVEGRKKLA
                     RLIVKVENPLEIEGILSKTDSIHRLYKGQNGYAFEIFSPEDDLILIHAEDDIASLVEV
                     GEKPEFQTDLASISLSKFEISMELHLPTDIESFLESSEIGASLDFIPAQGQDLTVDNT
                     VTWDLSMLKFLVNELDIASLRQKFESTEYFIPKSEKFFLCKDRNNVELWFEEV"
BASE COUNT         2189 a         1554 c         1326 g         2106 t
ORIGIN      
        1 ctcgcttttt taaactgagc ttaggctaaa agagtccact ggactctttt actccgtccc
       61 ataaccaatg atttaatggc gcattcagct agattattgg aaaggaccag atgtccgtct
      121 ttcaaaatag tcttaaaggt ttctttatac ttgaggctat acttgaggct gtattcaatt
      181 gcccttccta gttttgaacc cgataaaact gactgacgcc ggcaccaagc aaagaaatct
      241 tccattaggg gttggagatg ttcttgacgt ttctgtagtc gttcatcagc tggcaaagcc
      301 tcccagtttc tttccaagga aaataactga ttacaataag ctaaaccttt agctcctaag
      361 gatgatttat tcgcttgctt gggggtcgct tcaaaaaact tccttctcac atgtacccaa
      421 catccaacaa gttcagcttc ttccagttga caataagctt ctagcggttc gcagtttacc
      481 aagcttagcg tcgccttgct cctaaacctt ggactgctat cgcataggca gaactagagg
      541 actaaagtcc taagttactg ccgcaacata tcacaatgca catagccaga ataatctcct
      601 aggaattctt gcactaccga accactccga cgctgatcat ggtggtacag cgtgattgct
      661 tgattctcag ctttcccaga caaaaaggtc caatagtagg tcagatggct atcattctct
      721 agaacccgat aggaggtttc atctgcatga agtaagggct gaatcaatag tctcgttata
      781 aaggggcttt aggaatagga gcttttacaa ttttatcact tggattattc ttactgcatg
      841 tttggcattt gtaagcgtgt tggatatgat ccactctttt taattgcgca ggaataaaga
      901 ccaattcttg tcgttgaagg ctcgctccaa tctcttttaa atcgtcctga caatcagggc
      961 aaatgctctc ttctacttga tgatgaactt cttctgaatc aaattgggca agaatagctt
     1021 gacgtttccc tttagatttc ttacgtttgt aggtaatttc ctctgtttca actgggaaca
     1081 tctccatctt tctcagatgg agactcttcc tcaaaaaggt tgagttgtcc aaaagggcaa
     1141 acacttttct cagaggattt tccagagagc ttttgcgtta gataagccac ttgttcacac
     1201 agaagggaaa gttcattagt gagactatca attatagcac tctgttgttg aatgattttc
     1261 aatcttctcc catagacttt cctccttatt tcctaacttt attatatagt gtattgaatc
     1321 tataacagta caccttgact gctaaaatat ttctataaat taatttgact ttcctgatag
     1381 agatgttcat atcttatttc aattcactat actaaaaaga aagtcctcat ttcaatagaa
     1441 atcacgactt tctgataaat ttattttggg agtgatagaa aagcccttca taagccaatc
     1501 tacttgttca ggtgtgagag ctttgacatc cttttctgta ctgggccaag tcagtctgcc
     1561 gttctcaaag cgtttatata gtagccaaaa tccttgacca tcccagtaaa gggctttaaa
     1621 gcggtcttta cgtccaccac aaaagagaaa aacttgaccg gagaaaggat ccaattcaaa
     1681 gtgggtttta accagataag ccagtgaatc gattccttgt ctcatatcag tcttcccaca
     1741 cacgagatag acctgcccta ggctagatag atgaattgtc atagagcaac accttatcca
     1801 aaagctgttc taccatttcg agattgagag attgaaaaaa acttacttca agcttgccaa
     1861 tacgaattta aagcagaata tcatttctct ttttagaatc aaaaggacga gattgtggaa
     1921 tctctacagg aacaataggt tgtggcatta aaatatcctc caatagtttt actttactaa
     1981 tagtatacag gaggaactcc atgaatgata gataccttgt tatgacgcgc ttactatatt
     2041 agaaagttgg ctctctaatt aaattaattc tcattatata tatcaaaaga ccgcagtttg
     2101 aaaactacgg tctaattttt tgtccaaatg taaatcactt ggaactatta ttcaatttat
     2161 tctttttagt aaatgttccc gttttaatcc cagttacagt ttttaatcct ctgtaaccgt
     2221 tgattttaca aagcttttaa tttttttgcg attactccca ctcaactgtt gcaggtggtt
     2281 tacttgtaat atcgtagacg atacggttaa catgatccac ttcatttacg atacgtactg
     2341 agattttttg aagtacttcc catggaattt tggcaaaatc agcagtcata ccatcgatag
     2401 aagtgatagc acggattgca atcgtgtagt catacgtacg accgtcaccc ataacaccga
     2461 ctgaacgaac gcctgtgtta acagtgaagt attgccaaat atcgcggtca agtccagctt
     2521 tagcgatttc ttcacgaaga atagcgtctg attcacgaac ggtttcaagt ttctcttcag
     2581 tgatttcacc catgacacgg atagcaagtc ctggtcctgg gaatggttgg cgccatacga
     2641 tatggtctgg cataccaagc tctgtaccaa gagcacgaac ttcatccttg taaagagtat
     2701 tgagtggttc aatcaattca aactgcatat cttctggaag accacctacg ttgtggtgtg
     2761 acttgatagt ttgagctgta tccgtaccag actcgataac atctgtatat aaagtacctt
     2821 gagcaaggaa tttcacatct ttgagcttgc ttgcttcgtc atcgaataca tagacaaact
     2881 cgttaccgat gattttacgt ttttgttcag gatcagaaac gccagcaagt ttgtcaagga
     2941 aacgtttagc agcgtctgct ttgacgatat tcaaaccaaa cttaccaccg agcatgtcca
     3001 taacttgatc agcttcgcct ttacgaagaa gaccgtggtc tacgaagata cagatcaatt
     3061 gatcgccaat cgctttttgg agaagaaccc caacgacaga tgagtcaaca ccacctgata
     3121 gaccaagaag gacacgttta tcaccgacgg tttcacgaat ttttttgatc tgcatgtcaa
     3181 tgaaattatc cattgaccag tcacctttag ccttacaaat gttaagggca aagttacgaa
     3241 ggatatcatt tccgtataca gaatgacgaa cttctgggtg gaattggata ccgtaaatgt
     3301 gtttatctgg gttttcgatg gctgcgtata ggcagtcagc tgatgtacct gtacgaacaa
     3361 agtcagcagg aatctcagta accgcatcac catggctcat caaaacagtc tgttcatcag
     3421 gtgttgattc aaaaagcgct gatggtgtgt gagttagggt tgattgaccg tattcacgat
     3481 ttccagcatc acctgcagga acaacttttc ctccaagttt atgggtcaat aactgcatac
     3541 cataacagat tcccaaaatt ggaattccga gttcgaagat ttctgggtca atatcaaatg
     3601 aaccatcttc atatacagaa tttggaccac ctgatagaat aattcctaca ggattgactt
     3661 cacgaacttc agcagctgaa attttatggc tttttagttc tgaaaaaaca ccaatctcac
     3721 ggatacggcg tgaaatcagc tggttgtact ggctaccata gtccaatacg atgatttttt
     3781 ctacatcttg caaatcagtt gaaatgttgc tcatcttttt cctttctcaa aagaaatatc
     3841 ttttctcaat attctatcac aaataagggc gaattaccaa ctaaacaagg cgaagtttga
     3901 ctttttctag tttattgggg tacaatagag aaaagataga aatgaagtga aaaatatgct
     3961 acctgcttat atgaaaatcc atgatcagat aaaaaaggat attgacgagc accgttgggc
     4021 tattggtgag aggcttccca gtgaaagaga tttagctgag cagtttgcgg tcagtcgcat
     4081 gaccctccgc caagccgtat ctctattagt cgaagaaggc gtcttagagc gccgtgtagg
     4141 aagcggcacc tttgtttcca gtactcgagt acaagaaaag atgcgaggga caaccagttt
     4201 tactgaaatt gtcaaatccc aaggtaaagt tccctctagc cagctcattt cctacaaaaa
     4261 aaccattccc aatgagcaag aagttgccaa gctaggaatt tttccaacgg acaatattat
     4321 ccgaatggag cgggtccgct atgccgacca agttccccta gtttatgaag ttgcttctat
     4381 tcctgaaaaa ttcattaagg actttaaaaa agaagaaatc accagtcatt tcttccaaac
     4441 cttgcaaaaa catggctatc gtatcggcaa atctcaacag accatctatg ctcgccttgc
     4501 taaagaaaag attgcccact atttggaagt tgaaaaagga catgctattc ttggattgac
     4561 ccaggtttcc tacctagaag atggtactgc ttttgaatac gtaaaaagtc aatatgtagg
     4621 cgaacgcttt gaattttatc ttgaaaataa ttagattacc acgcaaaaac tctctgtcac
     4681 ggacaaagag tcttttttat ttttctaaga ataaatcttt caaagaaatc aaagttacag
     4741 caaacaatat cattgccata ccaataaaat caatgggata aaattgttca ttcattatta
     4801 agaaggcaaa gaaaaccgcc gatattggct caattgaagc caacaagctt gacttgaccg
     4861 gtcctatcag actggctcct ttaaggaaag ctgtataggc aaagacagtc ccgataagga
     4921 taatgcctgc aaacgcaagg agaaaatcaa gactagtcgg gatatcggcc tgtagaaccc
     4981 ctgtaaaagg aagggcgacc aaacctgcta tgaccatccc cacaccaatg accaagctgc
     5041 tcccccactt tttaatcaag gctatgggta aaatgatata caaagcataa gtcaaggcag
     5101 aaaagagacc ccagaacagg ccagcaggtg tcatggataa ctggtccaac tgcccatgtg
     5161 ttgcgatcag gaaggttcct ccgatggcga atatgatgga aactatctct cccagtgtcg
     5221 gtgccaccct atccttgata cagctataaa ttaaaattcc gacaggacaa acatactgaa
     5281 gcaccgtcgc tgttcccgca ttggtctcct gaatagcaga cagataggcg aattggttga
     5341 gaaaaagacc aatcagagca aaaataagaa gagacagcaa actctttcta tcctttaaaa
     5401 agaccagtat tttatccttt gcagtagcat aagccaagag catgagaatt ccaccagcga
     5461 ttaaaagacg caagttggtc aagaccagag ccgaaattcc gtgtgccatt aggtattggc
     5521 cactcgttcc tgacaacccc caagcaatac cagccacaac tgttagtaaa gtccctttta
     5581 aactatttga catgtctctc cttactcttc tttgcgaatc aagttcatca cttgattgcg
     5641 gtctaatatc cattgagctc tctcgtcctt ttcataggta cgattcgata ggaaaatagt
     5701 ggcttcttgc ttctgacgat tccacatgat aaaggtacct gtatagcccg tatggtctag
     5761 ccaatctcct tccaaattcc atgctaaaga acgttccttg tcatccaaag gagaaaaatt
     5821 ttgatttaag tctcttgcaa aatcatctgc taaatagtgt tctaaaaaga tttgtaaatc
     5881 ctttatagtc gaaaataaac cagcactccc agcatgtcta cccaggagac gagccttggg
     5941 atcatgcact atgcctgcct ctacacctct aactgttgga acagcaagct caactggccc
     6001 aaacttggtt tccgtcattc cccaaggttt ccagacttga tcctttaaaa tcacatccaa
     6061 atcttgatta aaaattcttt ccaaaataaa gcccaacagc aaaaaatgga catccgaata
     6121 aagaaaggct ggctgacttc gtctgttgag atgaaacatc gcttccttta attcaggggc
     6181 tgttaaaaga tcacgattag gaataaaagg atcaaggtct gttgcatgag tcaagagctg
     6241 gcgaatagtg atgtctggat aatcactctc aggtaaaaaa tctattacca gtctatcaat
     6301 atctaattga cctatttccc acaagaaggt acaaactgtg ccaaccccaa caaccttgct
     6361 gacactagct aggtcataaa ctagtcctgc ctcagtctgc aagccatgct ctgggtcact
     6421 ctggcctaaa tagaactctg tccattgatt gtccttaaaa tacgcaaaag aggctccggg
     6481 ataaattcct gcctcgattt gttcttctat ttttttaata atcttggtcc acttcatact
     6541 tcttcaaacc acaattcaac attatttcta tctttacaaa ggaagaattt ttcagactta
     6601 ggaataaaat attcagtaga ctcaaacttc tggcgaagac ttgctatgtc taattcattg
     6661 accaagaact tgagcataga taagtcccag gtaaccgtat tgtccacagt caaatcctgc
     6721 ccctgagctg gaataaaatc aagggatgcc ccaatttcag atgattccaa gaaactttcg
     6781 atatcagttg ggagatgtaa ttccatagaa atctcaaatt tacttaaaga aattgatgcc
     6841 aaatctgttt gaaattcagg cttttctcct acttctacta gacttgctat gtcatcttcc
     6901 gcatgaatca aaatcaaatc atcttctggt gagaaaattt caaaagcgta gccattttga
     6961 cctttatata atcgatgaat cgaatctgtt ttagataaga ttccttcaat ttctaaggga
     7021 ttttccacct tgacaatcaa tctagctagt ttttttcttc cctctacctt acgagtacgc
     7081 atactgggag cttcttctaa aaccagcttt tcaagacccg tttggtcacc tagtgacaga
     7141 aaggccgatt cttctaacaa ggccttcatt ccaag
//
LOCUS       DAVLBE010000076         6958 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.076, whole genome shotgun sequence.
ACCESSION   DAVLBE010000076 DAVLBE010000000
VERSION     DAVLBE010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6958)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6958)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6958
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.076"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            1..380
                     /locus_tag="VXB91_001851"
                     /pseudo
     CDS             1..380
                     /locus_tag="VXB91_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
     gene            547..747
                     /locus_tag="VXB91_001852"
     CDS             547..747
                     /locus_tag="VXB91_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0471256.1"
                     /translation="MVASASASSTSTQAQEQVDKSELRALSQELDQRLKALATVSDPK
                     IDATKAVLLDAQKAPEDSALTE"
     gene            789..1194
                     /locus_tag="VXB91_001853"
                     /pseudo
     CDS             789..1194
                     /locus_tag="VXB91_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377663.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1425..2132
                     /gene="ccdA2"
                     /locus_tag="VXB91_001854"
     CDS             1425..2132
                     /gene="ccdA2"
                     /locus_tag="VXB91_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEV0471257.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLPVYAGILLDDQESAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYGMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDSNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLALASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            2143..2700
                     /gene="sdbB"
                     /locus_tag="VXB91_001855"
     CDS             2143..2700
                     /gene="sdbB"
                     /locus_tag="VXB91_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HEV0471258.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGEEETKKTQAAQQPKQQTTVQQIA
                     VGKDAPNFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKIVEQFPQWFQEQGYKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAEAAFKEMN"
     gene            3074..4465
                     /locus_tag="VXB91_001856"
     CDS             3074..4465
                     /locus_tag="VXB91_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEV0471259.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPAWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGIAFPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIMAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKIPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLIMLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
     gene            4608..5525
                     /gene="adcAII"
                     /locus_tag="VXB91_001857"
     CDS             4608..5525
                     /gene="adcAII"
                     /locus_tag="VXB91_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HEV0471260.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDADVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLESDPQNDKTYLENLEENMSILAEELK"
     gene            5533..>6958
                     /gene="phtD"
                     /locus_tag="VXB91_001858"
     CDS             5533..>6958
                     /gene="phtD"
                     /locus_tag="VXB91_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtD"
                     /protein_id="HEV0471261.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRHQAGQVKKESNRVSYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVIKVDGKYYVYLKDAAHADNIRTKEEIKRQKQER
                     SHNHNSRADNAVAAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKNEL
                     SASELAAAEAYWNGKQGSRPSSSSSYNANPVQPRLSENHNLTVTPTYHQNQGENISSL
                     LRELYAKPLSERHVESDGLIFDPAQITSRTARGVAVPHGNHYHFIPYEQMSELEKRIA
                     RIIPLRYRSNHWVRDSRPEQPSPQSTPEPSPSPQPAPNPQPAPSNPIDEKLVKEAVRK
                     VGDGYVFEKNGVSRYIPAKNLSAETAAGIDSKLAKQESLSHKLGAKKTDLPSSDREFY
                     NKAYDLLARIHQDLLDNKGRQVDFE"
BASE COUNT         2158 a         1284 c         1457 g         2059 t
ORIGIN      
        1 aactaccatc cactatgcgc tcaaagcgat gggttacact cgaaaaaaag aaccacacct
       61 actatgaaca agacccagaa aaagtagcct tatttcttaa gaattttaat agtttaaagc
      121 acctagcacc tgtttagatt gatgaaacag gattcgatac ttatttttat cgagaatatg
      181 gtcgctcatt aaaaggtcag ttaagaagag gcaaagtatc tggaagaaga tatcagagga
      241 tttctttggt tgcaggtcta acaaatggtg aattaatcgc tccaatgact tacgaagaga
      301 tgatgacgag cgactttttt gaagtatggt ttcagaagtt tctcttacca acattaacca
      361 caccatcggt tattatagta aaatgaaata agaacaggac aaatcgatca ggacagtaaa
      421 atcgaattct aacaatgttt tagaagtcca tatgtactat tctagtttca atataccata
      481 actgttccta gtcaacctgc aagccctgtc ccagctccaa gctcagctcc gactcaagat
      541 cctagagtgg tagcaagcgc ttcggctagc tcaacgagca cacaagctca agagcaagtt
      601 gacaagtctg aacttcgtgc cttgagtcaa gagttagacc aacgcttgaa agctttggca
      661 acagtatctg atccgaaaat cgatgcaacc aaggctgtcc tcctagatgc tcaaaaagct
      721 ccggaagata gtgccttgac agagtaaggt ctgcatactg cagtagagtc tgtgaaggct
      781 gggctgcctt ggactctctc aaagatgtga aagcaaatgc tagcgacagc aagcctacac
      841 aggacaagaa ggatgcaaaa caaggaacgg aagatagtaa ggattcagat aagatgactg
      901 aaacaaactc agttccagca ggagtgattg tggtcagtct acttgccctc ctaggcgtga
      961 ttgccttctg gctaattcgc cgtaagaaag agtcagaaat ccagcaatta agcacggaat
     1021 tgaccaaggt tctaggacag ctagatgcag aaaaaagcgg ataaaaaagt ccttaccaaa
     1081 gcccaaaacc ttctccaaga aacccttgat ttcgtgaaag aagaaaatgg ctcagcagag
     1141 acagaaacta aactagtaga ggagcttaaa gcaatccttg acaaactcaa gtaaaacatg
     1201 atttatgaaa tgtcagacct aaaagacatt ttcgttcaca aaagcagcga cgagtaatcc
     1261 ttgtcgttgc tttttggcta ttttggggga taagatccgc cttgactagc aaaagaaaag
     1321 attggtccaa tagtgcccga tacgattttg cgtagcagaa agcttacaaa taaaattgaa
     1381 tatagtaaaa taggattaga attattaaga aagttggttc tttattggaa acgatagtat
     1441 ttttaatctc tgtttttcta gcaggtgttt tatccttttt ttctccttgt atttttcctc
     1501 ttctgccagt ctatgctggg attttattgg atgatcaaga aagtgcaaaa agcttttctt
     1561 tgtttgggag aaaggttctc tggtcaggct tgattcgaac actttgcttt atcgctggta
     1621 tctctctcat tttctttatt ctaggctttg gtgctggtta ctttggtcat attctctatg
     1681 caaattggtt tcgatatggc atgggagcta ttattatcat tttgggtctt caccagatgg
     1741 aaatttttca tttgaagaaa ttagaagttc aaaaaagttt tacctttaaa aaatcagact
     1801 ctaatcgtta ttggtcagct tttttacttg gtattacctt tagctttggt tggacacctt
     1861 gtattggtcc agttttaagt tctgttttag cacttgcggc ttctggaggc aatggcgctt
     1921 ggcaaggagc gatttatact ctcatttaca ctctgggcat ggcccttcct ttcttggtat
     1981 tggcactagc ttcaggtcta gtcatgccat attttagtaa aatcaagcgt catatgatgc
     2041 tactaaagaa aattggtggt ttcctcattg ttttaatggg aattttgtta ctattaggac
     2101 aagtaaatgt tctagctgga atttttgaat aaaggaggac aaatgaaaaa agtaatgttt
     2161 gctggcttaa gtctcttgtc attagttgta ttgatggcct gtggtgagga agaaactaaa
     2221 aagactcaag cagcacaaca gccaaaacaa caaacgactg tacaacaaat tgctgttgga
     2281 aaagatgctc caaacttcac attgcaatcc atggatggca aagaagttaa gttatctgat
     2341 tttaagggta aaaaggttta cttgaagttt tgggcttcat ggtgtggtcc atgcaagaaa
     2401 agtatgccag agttgatgga actagcggcg aaaccagatc gtgatttcga aattcttact
     2461 gtcattgcac caggaattca aggtgaaaaa attgttgagc aattcccaca atggttccag
     2521 gaacaaggat ataaggatat cccagttctt tatgatacca aagcaaccac cttccaagct
     2581 tatcaaattc gaagcattcc tacagaatat ttaattgata gccaaggaaa gattggaaag
     2641 attcaatttg gtgctatcag taatgcggat gcagaagcag catttaaaga aatgaactag
     2701 aatcgataaa atctgattac aagatgtagt cagattttgg taacttctaa aactaacttc
     2761 cagtttccca caacctagct tttagtatga gaaaaacgcg tgacatcagt ggaaatccgt
     2821 cttagactaa cttccactgg ttttcttttt cttgatatat aagggttcaa aagcgaaaag
     2881 actcagaaaa agtgcacgac aaatagccct aaaacagagt cgtcttagag taacttccag
     2941 ttttgggaga gagatggaag ttactttgag aagttacggt agtcagattt ttttagaaaa
     3001 acattttata aatattcaca tatctcctat atttatggta aaatagaatc atcagtttat
     3061 tttggagtca aagatgaata tatttagaac aaagaatgtt agtttagata aaacagagat
     3121 gcataggcat ttgaagttat gggatttgat tttgctgggt atcggagcca tggtagggac
     3181 aggcgtcttt acaatcacag gtactgcagc tgcaacactt gctggcccag ccctagtgat
     3241 ttcaatcgtt atttctgcct tgtgtgtggg attatcagcc ctcttttttg cagaatttgc
     3301 ctcgcgagta cccgctacag gaggtgccta tagttacctc tatgctatct taggagaatt
     3361 ccctgcctgg ttggctggtt ggttaaccat gatggagttc atgacagcca tatcaggcgt
     3421 agcttcgggt tgggcagctt attttaaagg cttgctctct caatacggga tagcctttcc
     3481 tcaggcttta aatggtacct ttaatcctca agcagggaca tttgttgatt tattgcctat
     3541 tcttgtcttg gtcttggtga cttcgcttgt tttactaaat gccaaggcag ccttacgctt
     3601 taattcgatt ctagttattt tgaaattttc cgctttagct ctctttgttt tagtaggaat
     3661 ttggaatatt aagtttgata attggagcaa ttttgctcct tacggttttg gacaaatcta
     3721 tggagctagc actggtatta tggctggtgc gtccttgatg ttcttcggtt ttttgggatt
     3781 tgaatccatc tctatggctg tagatgaagt caagactcct caaaaaaata ttcctagagg
     3841 gattgtctta tcgctttcta tcgtaaccat tctctatgcc ttggtgaccc ttgttttgac
     3901 tggtgtggtt cactatagtc atttaaatgt cgatgatgcc gttgcctttg cccttcgtag
     3961 tgttgggatt agttgggcag ccaactatgt gtcattagtg gctatcttga ccttgattac
     4021 agtttgtatt tcgatgacct atgccctatc gcgtatgatt tacagtttag cacgtgacgg
     4081 cttagtgcct gctgccttta aggaactgac gaagactagc aagataccaa agaatgctac
     4141 tatcttgaca ggtctagctt cagcagtagc agcaggaatg ttcccactag ccagtattgc
     4201 agccttttta aatatttgta ccttagccta cttgatcatg ttggcttatg gtctgattcg
     4261 cttacggaaa gaaaaaggaa tgcccaaagc tggggaattt aaaacaccat tggtacctct
     4321 gttaccaatt ttatcgatca tcatttgttt atccttcatg ttacagtata atatgaatac
     4381 ctggattgct ttcctagttg cgttgttagt aggaagtatt atttacttca cttatggcta
     4441 taagcattct accatagaag aataaagtga aagtctattg agttgttgac actcagcaga
     4501 tttttatatg tgaaagaaat ttcaaatttt ttctaaaaat atcttgacag attaaatttt
     4561 caggagtaga atatttacta gttaattaaa tggttaagga gttgttcatg aagaaacaaa
     4621 atttattttt agtcctgtta agtgtctttc ttttgtgctt gggggcttgt ggtcaaaagg
     4681 aaagtcagac aggaaagggg atgaaaattg tgaccagttt ttatcctatc tacgctatgg
     4741 ttaaggaagt atctggtgac ttgaatgatg ttcggatgat tcagtcaagt agtggtattc
     4801 actcctttga accttcggca aatgatatcg cagccatcta tgatgcagat gtctttgttt
     4861 accattctca tacactcgaa tcttgggcag gaagtctgga tccaaatcta aaaaaatcca
     4921 aagtgaaggt cttagaggct tctgagggaa tgaccttgga acgtgtccct ggactagagg
     4981 atgtggaagc aggggatgga gttgatgaaa aaacgctcta tgaccctcac acatggctag
     5041 atcctgaaaa agctggagaa gaagcccaaa ttatcgctga taaactttca gaggtggata
     5101 gtgagcataa agagacttat caaaaaaatg cgcaagcctt tatcaaaaaa gctcaggaat
     5161 tgactaagaa attccaacca aaatttgaaa aagcgactca gaaaacattt gtaacacaac
     5221 atacagcctt ttcttatcta gcgaagagat ttgggcttaa tcaacttggt attgcaggta
     5281 tctctcctga acaagaacca agtccacgac aactaacaga aattcaggaa tttgttaaga
     5341 cctataaggt taaaacgatt tttacagaaa gtaacgcttc ttcaaaagta gctgaaactc
     5401 ttgtcaaatc aacaggtgtg ggtcttaaaa ctctgaatcc tttagagtca gacccacaaa
     5461 atgacaagac ctatttagaa aatcttgaag aaaatatgag tattctagca gaagaattaa
     5521 agtgaggaaa gaatgaaaat caataaaaaa tatctagcag gttcagtggc agtccttgcc
     5581 ctaagtgttt gttcctatga acttggtcgt caccaagctg gtcaggttaa gaaagagtct
     5641 aatcgagttt cttatataga tggtgatcag gctggtcaaa aggcagaaaa tttgacacca
     5701 gatgaagtca gtaagagaga ggggatcaac gccgaacaaa ttgttatcaa gattacggat
     5761 caaggttatg tgacctctca tggagaccat tatcattact ataatggcaa ggttccttat
     5821 gatgccatca tcagtgaaga acttctcatg aaagatccga attatcagtt gaaggattca
     5881 gacattgtca atgaaatcaa gggtggctat gtgattaagg tagacggaaa atactatgtt
     5941 taccttaaag atgcggccca tgcggacaat attcggacaa aagaagagat taaacgtcag
     6001 aagcaggaac gcagtcataa tcataactca agagcagata atgctgttgc tgcagccaga
     6061 gcccagggac gctacaccac agatgatggt tatatcttta atgcttctga tatcattgag
     6121 gacacgggtg atgcttatat cgttcctcac ggcgaccatt accattacat tcctaagaat
     6181 gagttatcag ctagcgagtt agctgctgca gaagcctatt ggaatgggaa gcagggatct
     6241 cgtccttctt caagttctag ttataatgca aatccagttc aaccaagatt gtcagagaac
     6301 cacaatctga ctgtcactcc aacttatcat caaaatcaag gggaaaacat ttcaagcctt
     6361 ttacgtgaat tgtatgctaa acccttatca gaacgccatg tggaatctga tggccttatt
     6421 ttcgacccag cgcaaatcac aagtcgaacc gccagaggtg tagctgtccc tcatggtaac
     6481 cattaccact ttatccctta tgaacaaatg tctgaattgg aaaaacgaat tgctcgtatt
     6541 attccccttc gttatcgttc aaaccattgg gtacgagatt caagaccaga acaaccaagt
     6601 ccacaatcga ctccagaacc tagtccaagt ccgcaacctg caccaaatcc tcaaccagct
     6661 ccaagcaatc caattgatga gaaattggtc aaagaagctg ttcgaaaagt aggcgatggt
     6721 tatgtctttg agaagaatgg agtttctcgt tatatcccag ccaagaatct ttcagcagaa
     6781 acagcagcag gcattgatag caaactggcc aagcaggaaa gtttatctca taagctagga
     6841 gctaagaaaa ctgacctccc atctagtgat agagaatttt acaataaggc ttatgactta
     6901 ctagcaagaa ttcaccaaga tttacttgat aataaaggtc gacaagttga ttttgagg
//
LOCUS       DAVLBE010000077         6931 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.077, whole genome shotgun sequence.
ACCESSION   DAVLBE010000077 DAVLBE010000000
VERSION     DAVLBE010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6931)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6931)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6931
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.077"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(77..352)
                     /locus_tag="VXB91_001859"
     CDS             complement(77..352)
                     /locus_tag="VXB91_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HEV0471262.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
     gene            complement(459..1298)
                     /locus_tag="VXB91_001860"
     CDS             complement(459..1298)
                     /locus_tag="VXB91_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEV0471263.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVTVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILSHVEEVKNHTELYIGV
                     STLENLVKGGRISRVTGLLSSLLNIRVVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            1440..2288
                     /locus_tag="VXB91_001861"
     CDS             1440..2288
                     /locus_tag="VXB91_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEV0471264.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSAWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFISGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
     gene            complement(2381..3298)
                     /locus_tag="VXB91_001862"
     CDS             complement(2381..3298)
                     /locus_tag="VXB91_001862"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HEV0471265.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRTIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVDQLKADEEVTRNWS"
     gene            3735..3940
                     /locus_tag="VXB91_001863"
                     /pseudo
     CDS             3735..3940
                     /locus_tag="VXB91_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844775.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            complement(4251..4544)
                     /gene="rpmA"
                     /locus_tag="VXB91_001864"
     CDS             complement(4251..4544)
                     /gene="rpmA"
                     /locus_tag="VXB91_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HEV0471266.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(4561..4905)
                     /locus_tag="VXB91_001865"
     CDS             complement(4561..4905)
                     /locus_tag="VXB91_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HEV0471267.1"
                     /translation="MIQAVFERAEDGELRSAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENY
                     SEFVQTRVITEN"
     gene            complement(4921..5235)
                     /gene="rplU"
                     /locus_tag="VXB91_001866"
     CDS             complement(4921..5235)
                     /gene="rplU"
                     /locus_tag="VXB91_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HEV0471268.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYVEKLNVEAGQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     misc_feature    complement(5271..5358)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(5417..6121)
                     /locus_tag="VXB91_001867"
     CDS             complement(5417..6121)
                     /locus_tag="VXB91_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004241810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HEV0471269.1"
                     /translation="MGGKMRLLPIRKISRQSKRLALFLTFCAGYVDAYTFIVRGNTLV
                     AGQTGNVVFLSVELIKNNVSDVRDKVLTLLAFMMGVFLLTIYKEKLRIVKKPILSLIP
                     LAILSIIIAFVPQTVDNIYLVPPLAFCMGLVTTAFGEVSGIAYNNAFMTGNIKRTMLA
                     FGDYFRTKHTPFLREGFIFVSLLSSFVLGVVFSAYLTIFYHEKTILGVPIMMSVFYLS
                     MLFASWQKKVKEKASF"
     gene            6523..6822
                     /locus_tag="VXB91_001868"
     CDS             6523..6822
                     /locus_tag="VXB91_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HEV0471270.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF"
BASE COUNT         2182 a         1407 c         1158 g         2184 t
ORIGIN      
        1 tattactaga tttcataatt aaaaagccta ctgaccaagc tagaaagctt gatacaatag
       61 gctttttaaa gactgattat ttaacagcgt ctttaagagc tttaccagct ttgaatgctg
      121 gtactttaga agctgcaatt gtcatttctt taccagtttg tgggttgcga cctttacgtt
      181 ctgcgcgctc acgaacttca aagttaccaa aaccgatcaa ctgaactttt tcaccagctg
      241 caagatagtc agctactgct gcaaatacag cttcaactgc tgctgctgag tctttcttag
      301 tcaattctgt agcttctgct actttagcga tcaaatcttg tttgtttgcc atgttaatga
      361 ttcctccaaa taatttctaa ttaacaaata taatcatatc ctaaaatccc ttttaggtca
      421 agttaaaaac gctatttctt cccattttat ttattttttt aggagtggta acgtatcaaa
      481 atagcccaag cgttctcacc cgtgtgagtt tgaataatgg aacccgtttc caaaacagaa
      541 attggctttt caacataagc ttgtaagctt tctttcatct cttttgccca atcatcacta
      601 ccagaatatg aaattccaat ctctgctaca gcacgttcag aaagcgatgt tatcaactca
      661 tctaaccatt ttttaaatgt tttagttcca cgacctttaa ccattggctg caattcatgg
      721 tctttcattt gcatgacaac acggatattg agaagagagc tcaacaagcc agttacacgg
      781 ctaattcgtc cacctttgac aagattttcc aaagttgaaa caccaatata aagctctgta
      841 tggtttttaa cctcttctac atgagataaa attgcctcca tatctttacc ttcttgagct
      901 aacttcgcag cctcaacaac ttggaatttc agggcttggt cagtgaagga actatcaaca
      961 acagtcacat ctgcagtaga taggctagca ccttggcgtg ctgcttctac cgtacccgaa
     1021 agagcatggg acatatgaat agcaagaatc tggccaccat ctttgcatag gtcttcaaaa
     1081 atctcagcaa agacacctac aggtggctga cttgttttcg gaagattctt actttcttgc
     1141 atcaactgaa gaaatttacc ttcttctttc aaatccgcat cagaataaac aacattatca
     1201 atcattacag ataatggaac aattgtaata tctaattgct ttactagttc aggttcaata
     1261 gtaacagatg aatcggttac aatcttaatt tttgtcatag tatcaatctt tctattttag
     1321 gattcagatt ggtttcctta cttctaatta tatcaaaaaa aagattaaaa atcctaatgg
     1381 agtcaatcaa attttccgta aaatttgata taatcaactt ataagaaaag aggtgtccta
     1441 tgattaaaaa aatttacccc atttttacca ttttactagg tgctgctatt tatgcttttg
     1501 gactgactta ttttgtagtt ccccatcatc tctttgaagg aggggcgaca ggcattaccc
     1561 tcatcacctt ttatcttttt aaaatccctg tttccctcat gaacctgctg attaatattc
     1621 cccttttcat cctagcttgg aagatctttg gagccaaatc cctctattct agtttactag
     1681 gaaccttagc tttgtccgcc tggttagctt tttttgagca tattcccctt catattgatc
     1741 ttcaaggtga tttactaatc acagccctta tagcgggaat cctattggga attggccttg
     1801 gaattatttt taatgctgga ggtacaactg gcggaactga tattctagct cgtattctca
     1861 acaaatacac tcatatatcc ataggaaaac tgctctttat cttagatttt tgtattctca
     1921 tgttgattct cctaatcttc aaggatttga gattggtttc ctacacgctt ttgtttgatt
     1981 ttattgtttc tcgtgttatt gatttgattg gtgaaggagg atatgccggc aaaggcttta
     2041 tgattatcac aaaacgtcct gaccaacttg ctaaggcgat taatgatgac ctcggaagag
     2101 gtgttacttt tatttctggt caaggctact atagtaaaga aaatttgaaa atcatctact
     2161 gtattgtcgg aagaaatgaa attgtgaaaa cgaaggaaat gattcatcga atcgatcctc
     2221 aagcctttat aactattaca gaagcccatg aaatcctagg agaaggcttc acctttgaaa
     2281 aagaataaaa agaggtaatg tcgtgacctc aaaagttaga ctaaatcatc tatcttttgg
     2341 gttacagaca acctcttttt tgttttattt actcaagctc ttaagaccaa ttccgagtta
     2401 cttcttcatc agcctttaac tgatccacta attggtcaac tgagtcaaat ttggtcatat
     2461 cacgaatgcg atcaagccaa taaaccatga cggtttcccc ataaatatct tgattaaaat
     2521 caaaaatatt gacttcaaaa cgtgcttctt ctccatcaaa ggtcacattt ttcccgacac
     2581 tagccatagc acgatacttc tgtctttgaa tctcaacatc aacgacataa acgccatctg
     2641 ctggcatata agtacggtct aaaagcacta aattcgctgt cggataacca attgtacgac
     2701 cacgagcatt accatgaacc accatacctc ttgatggaag cggtgccccc aaaagttttc
     2761 ctgcttcttt cacatttcca tctaaaatag cttgacggat acgagttgaa ctaatctttc
     2821 ctttctcatc ttctacaggt ggaacaatga taacttctcc atcaaagtaa tcctttaaat
     2881 cttctgctgt ttttttgtca gaaccaaatg tataatcaaa acctgcaaca ataattttgg
     2941 cattcatagc cttgatataa gttgcaaaga attcttgtgc agtgagacta gcgaattgac
     3001 tactaaaatc aaggagatat aattcttcta caccttcgcg ctttaatttt ctttcacgtt
     3061 cagcagggtt caaaatatgc aaaaacaaat ctggatgata aggctctaaa gcgatctttg
     3121 gagattcatt aaaggtcata acgacgatag gcaataaatc ctttctcgca gccttgttgg
     3181 caacacgaaa taattcttga tgccccttat gtatgccatc aaaatagccg agaacaacga
     3241 ctgaatcaga tggtgtgcca atatcttttt ggttttttat aggaatagta ataatcataa
     3301 aataattata tcatagcgat agctatttct ggaacagaaa atctgaaatg ttgttttttt
     3361 cacatgaagt gtacctgttt tcaaaaagca ctttattcta tcgttgctta actatgaact
     3421 ttgcaatatt cttctcaaaa acttgtagga catcttcaaa attttgcaag gagtgattag
     3481 acttgttcgg taaccataaa gtgtcatact atgttatgta tgaaaaagca atgcaactaa
     3541 ctcctgagaa ctttaaatta ctaattggtg ccaaaaaggt agaatttaga atcgaggtac
     3601 acctatggct gtaaaattta caaaatgaga caacttgggc aagatgtttg aagaatttcc
     3661 taaactccct gatttgaagc aagtcacttt ccctgatgac aaagaaaaaa gccaaaacag
     3721 caaagaaaaa ctagatgact gctttccaac aactcccatc tagtgtgctt cagactgggc
     3781 tatttttctc tccatctgtt agcttggatt ctcagaccgt ttcagctaaa gaatatcttt
     3841 tcccttatca gaaggaacgg ctcaaaccat tcagacaagt gaagggacga caagccaata
     3901 tttgaaacca gatagcagtt cttatagtca attgaaataa aatctgaaga aatcgagtag
     3961 gaaactcata tcaattttta acagtgttct attccagatt catactcaat gaaaattaaa
     4021 gtgcaaacta ggaagttagc cgcaggctgt acttgagtac ggcaaggtga aattgacgtg
     4081 gtttgaattt gattttcgaa gagtatcaat ccactataca tattaaaaag tatgggtatc
     4141 aaaataaaaa aacaggctct ccgaaaactc ggaaagcctt attttaagct gtttctagct
     4201 tcctcacctt tacatttcaa ggttcgggat aaaaggttca atgaaccttt ttattttgcg
     4261 attgggtaaa cagaaacttg ttttttatcg cgtcctttac gttcaaagcg tactacgcct
     4321 tcaactttag cgaacaaagt atcgtctcca ccacgaccaa cgtttacacc tggatagatg
     4381 tgtgtaccac gttgacggta aaggattgat ccacctgtta cagtttgtcc gtcagctgct
     4441 ttagctccaa gacgttttgc ttgtgaatca cgtccgtttg atgtagaacc tccacctttt
     4501 ttgtgggcga aaagttgcaa gttgttaaga gtcattttta acataatgtt ttcctccgtg
     4561 ttagttttct gtgataactc tggtttggac gaactcagaa tagttctccg ataagtttgc
     4621 catacctaag aaaaatgatt caaagaataa ctgggtcatt tctctctggt gtgaaggaag
     4681 atcttttggt atttcaacca tcagatagcc accttcatct tcgtttaatt ctaggattgg
     4741 ttcatagcct gcaaatttct caatagaatt gataaagtta atggcaagcg tagaaaccga
     4801 tgcacacacg acatctaagc cgtattcgcc actctcggcg tgtccagtaa tttccgcact
     4861 cctcagctcg ccatcttcgg ctctctcaaa gactgcctgt atcatgtgtt ctccttaaaa
     4921 ttaagcgttg attgcgttga tgacaacttt tgtatatggt tgacggtgac cttgtttacg
     4981 gtggctacct tttttaggtt tgtacttgta agtaaccact ttcttttgtt ttccttgttt
     5041 ttcaacagtt ccaactacag tagctccagc aacaagtgga gttccgacaa cagtgttttc
     5101 accaccaaca agaacaactt cgttaaaagt aacttcttga ccagcttcaa cgttcaattt
     5161 ttcaacgtaa actgcttgac caacttcaac tttaacttgt tttccgccag ttttgataat
     5221 tgcgtatgtg ctcattatgc acctcctatg atttttatgg gtttccccga ttttttgtga
     5281 agactcgcct agcatcgtgg gacgaaccac ttaaacttga ataatcaagc aacgatgttc
     5341 gtgcggttgc acaggatcgt gcatagtcaa ctcttcaagt atagcatatc tcctattttc
     5401 ttacaagtaa taacacctaa aatgaagctt tttcttttac ttttttctgc caagaggcaa
     5461 aaagcatgct gaggtaaaaa acgctcatca taataggaac accaagaatg gtcttttcat
     5521 gatagaaaat cgtcaaatag gctgaaaaga caacgccaag gacaaaacta ctaagcaggc
     5581 taacaaatat gaatccttca cgcaaaaaag gagtgtgctt ggttcggaaa taatctccaa
     5641 aagccagcat ggtccgtttg atattccctg tcataaaagc gttattatag gcaatacccg
     5701 acacttctcc aaaagcagtt gtcaccagtc ccatacagaa ggccaagggc ggcactagat
     5761 agatattatc cacagtttgc ggcacaaaag caataatgat tgataagatt gccaagggaa
     5821 tcaaggacag aataggtttt ttcacaattc tcaatttttc cttataaatc gttaataaaa
     5881 agactcccat cataaacgct agcaaggtga gaaccttgtc cctaacatcc gaaacattat
     5941 ttttaattaa ttctactgaa agaaagacaa catttccagt ttgtccagct acaagggtat
     6001 tcccgcgaac aataaaagtg taagcatcca catatccagc acaaaacgtc aaaaaaagtg
     6061 ctaacctttt agactgacgt gatatttttc ttataggtaa taacctcatt ttacctccca
     6121 ttgtattttc tcttagaaat attgtaccat tttctttcta aaaaatcgta ggctaccatt
     6181 tagattttac tattagcata aaaataataa tagacaacta tttatccaaa aatagataga
     6241 tgtaacatgt ttgcaaacaa agcatacgaa cctttagtaa aatcatttcc atgaaactag
     6301 aatagagccc tcttagcaaa aatcattatt ttaatttatt tctaatcact ccttgacata
     6361 aataactctc accaataaaa gactatgtct taaaaaaatg gtataataaa atcaatactt
     6421 gggcttgatg gctatgctac taataacaat taggagagaa aatcaggcac ttgttaacaa
     6481 caaggattat ccccttgaga tgaaaggaac tttagaaatc ttatgatgaa catgcaaaac
     6541 atgatgcgtc aagcacaaaa acttcaaaaa caaatggaac aaagccaagc tgaacttgct
     6601 gctatgcaat ttgttggcaa atctgctcaa gatcttgtcc aagcgacctt aactggcgat
     6661 aagaaagttg tcagcattga tttcaatcca gctgtcgttg acccagagga ccttgagact
     6721 ctttctgata tgaccgttca agccatcaac tctgctcttg aacaaatcga tgaaactacc
     6781 aagaaaaaac tgggtgcttt cgctgggaaa ttacctttct aaaaacaagg agctagaaca
     6841 atgcttgtcg ataacaaagg ctaagaaagg tgcaaaaatg actctataat atttgtagtg
     6901 ggtaaatccc ctatagatat tatggagcct a
//
LOCUS       DAVLBE010000078         6823 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.078, whole genome shotgun sequence.
ACCESSION   DAVLBE010000078 DAVLBE010000000
VERSION     DAVLBE010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6823)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6823)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6823
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.078"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            <1..378
                     /locus_tag="VXB91_001869"
     CDS             <1..378
                     /locus_tag="VXB91_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HEV0471271.1"
                     /translation="RGKVSGRRYQRISLVAGLTNGELIAPMTYEEMMTSDFFEAWFQK
                     FLLPTLTTPSVIIMDNARFHRMGKLELLCEEFGHKLLPLPPYSPEYNPIEKTWAHIKK
                     HLKKVLPSCNTFYEALLSCSCFN"
     gene            464..1414
                     /locus_tag="VXB91_001870"
     CDS             464..1414
                     /locus_tag="VXB91_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEV0471272.1"
                     /translation="MGKKRWARNGSESNDASYAQVVSLYDDTSISVSNNETDKVLTGS
                     LYTETNEQGLTIPSSLLKNWNEQTGKNLTTNDLIGKSVSASIVESAAETSKIAQFQTK
                     IVRVINDEDDMEDSNSFMLSHQMETILKEAGFTKAVSYFILELKDPSQTKVVTEELQK
                     NKKYTVLSQQRVLDIVITFIRVIQGLLIVLSSQAIVVAAVMIGIIIYINIMQRSKEIG
                     VMKAVGYQNRGVKGIFIYEAIWIVGIALLLAFLVAQGVGSLANAIVSHFYPSITKVFE
                     LNLLSVLGTLVFALLLGYVSAYFPARKISKMDPVESLRYE"
     gene            1591..2598
                     /gene="gap"
                     /locus_tag="VXB91_001871"
     CDS             1591..2598
                     /gene="gap"
                     /locus_tag="VXB91_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HEV0471273.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFVKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHDVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(2666..3502)
                     /locus_tag="VXB91_001872"
     CDS             complement(2666..3502)
                     /locus_tag="VXB91_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEV0471274.1"
                     /translation="MTVKQLLEEQLLIPRKIRHFLRIKKHILINQEEVRWNEIVNPGD
                     VCQLTFDEEDYPQKTIPWGNPDLVQEVYQDQHLIIVNKPEGMKTHGNQPNEIALLNHV
                     STYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISREYWALVDGNINRK
                     ELVFRDKIGRDRHDRRKRIVDAKNGKYAETHVSRLKQFSNKTSLAHCKLKTGRTHQIR
                     VHLLHHNLPILGDPLYNSKSKTSRLMLHAFRLSFTHPLTLERLTFTTLSNTFEKELKK
                     NG"
     gene            3628..5823
                     /locus_tag="VXB91_001873"
     CDS             3628..5823
                     /locus_tag="VXB91_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEV0471275.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVELTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLKNMVAAGYI
                     DKNQETEAAEVDMTSQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQIVYENTSLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEAGWALNKQLDNHTMQYNSYKVDNYAGI
                     KTSREVPMYQALAESLNLPAVATVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIASHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYIMAGKTGTTEAVFNPEYTSDQWVIGYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
     gene            5876..6028
                     /gene="rpmG"
                     /locus_tag="VXB91_001874"
     CDS             5876..6028
                     /gene="rpmG"
                     /locus_tag="VXB91_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEV0471276.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            6038..6214
                     /gene="secE"
                     /locus_tag="VXB91_001875"
     CDS             6038..6214
                     /gene="secE"
                     /locus_tag="VXB91_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HEV0471277.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            6269..6805
                     /gene="nusG"
                     /locus_tag="VXB91_001876"
     CDS             6269..6805
                     /gene="nusG"
                     /locus_tag="VXB91_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HEV0471278.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAEL"
BASE COUNT         2123 a         1190 c         1480 g         2030 t
ORIGIN      
        1 agaggtaaag tatctggaag aagatatcag aggatttctt tggttgcagg tctaacaaat
       61 ggtgagttaa tcgctccaat gacttacgaa gagatgatga cgagcgactt ttttgaagct
      121 tggtttcaga agtttctctt accaacatta accacaccat cggttattat tatggataat
      181 gcaagattcc atagaatggg taagttagaa cttttatgcg aggagtttgg gcataaactt
      241 ttacctcttc ctccctactc acctgagtac aatcctattg agaaaacatg ggctcatatc
      301 aaaaagcacc tcaaaaaggt attaccaagt tgcaatacct tttatgaggc tcttttgtcc
      361 tgctcttgtt tcaattgact atagttcacg gatacagttg ggaaagaagc tattaaatat
      421 ttggagagtc cttttgggat gaacatgtca aatattacta tagatgggca agaaaagatg
      481 ggcaagaaat ggatctgagt caaacgatgc ttcttatgct caagtagtga gtctttatga
      541 tgatacaagt atctctgtta gtaataatga gacggacaaa gtgttgactg gatccctcta
      601 tactgaaaca aatgaacagg gattaacgat tccaagcagt ttactaaaaa attggaatga
      661 acagacagga aaaaatttga caactaatga tcttattggc aaatcagtct cagccagcat
      721 tgtagaaagt gctgccgaaa ctagtaagat tgctcaattt caaacgaaga ttgtacgtgt
      781 aatcaatgat gaagatgaca tggaggacag caacagtttc atgctgtctc atcaaatgga
      841 aacgattttg aaagaggctg gatttacgaa agctgtatct tattttatct tggaactcaa
      901 agatccatca cagacaaaag tagtaacaga agaattacag aaaaataaga agtatactgt
      961 gctttctcaa cagagagttc ttgatattgt gattaccttt attcgtgtta ttcagggatt
     1021 attgattgtg ctttcatcac aagctattgt ggtagcagcg gttatgattg gtatcattat
     1081 ttacatcaat atcatgcaac gttccaagga aataggtgtc atgaaagcag ttggttatca
     1141 gaatcgtggt gtcaaaggaa tttttattta cgaggctatc tggattgtag gcatcgcctt
     1201 gctgctggca tttttggttg cacaaggggt gggaagtttg gcgaatgcga ttgtaagtca
     1261 cttttaccca tccatcacta aggtttttga attaaatctt ttatctgttt taggaactct
     1321 agttttcgct ctattacttg gttatgtctc agcctacttc ccggcgcgta agattagtaa
     1381 aatggatcct gtagaatcgt tacgctatga ataataaggg attccttgat ttacagtctt
     1441 aaaaagaaac tcacatagaa aaacaatggc catacttgca attcaactca aatagttgta
     1501 taataggttt gttgaaaggt gatttgtagt gattcaagtt actcttttca caataaaaat
     1561 ttcatgattt tcataaggag gaaatcacta atggtagtta aagttggtat taacggtttc
     1621 ggacgtatcg gtcgtcttgc tttccgtcgt atccaaaacg tagaaggtgt tgaagttaca
     1681 cgcatcaacg accttacaga tccagttatg cttgcacact tgttgaaata cgacacaact
     1741 caaggtcgtt tcgacggtac tgttgaagtt aaagaaggtg gattcgaagt taacggtaaa
     1801 ttcgttaaag tttctgctga acgtgatcca gagcaaatcg actgggctac tgacggtgta
     1861 gaaatcgttc ttgaagctac tggtttcttt gctaagaaag aagcagctga aaaacacctt
     1921 aaaggtggag ctaaaaaagt tgttatcact gctcctggtg gaaacgacgt taaaacagtt
     1981 gtattcaaca ctaaccacga cgttcttgac ggtactgaaa cagttatctc aggtgcttca
     2041 tgtactacaa actgcttggc tccaatggct aaagctcttc aagataactt tggtgttgtt
     2101 gaaggattga tgactactat ccacgcttac actggtgacc aaatgatcct tgacggacca
     2161 caccgtggtg gtgaccttcg ccgtgctcgc gctggtgctg caaacatcgt tcctaactca
     2221 actggtgctg caaaagctat cggtcttgta atcccagaat tgaatggtaa acttgatgga
     2281 tctgcacaac gcgttccaac tccaactgga tcagttactg aattggtagc agttcttgaa
     2341 aagaacgtta ctgttgatga agtgaacgca gctatgaaag cagcttcaaa cgaatcatac
     2401 ggttacacag aagatccaat cgtatcttca gatatcgtag gtatgtctta cggttcattg
     2461 tttgacgcaa ctcaaactaa agttcttgac gttgacggta aacaattggt taaagttgta
     2521 tcatggtacg acaacgaaat gtcatacact gcacaacttg ttcgtactct tgaatacttc
     2581 gcaaagattg ctaaataatt cttgagttga tagaaagcaa ggctttgtgg tcttgctttt
     2641 ttatatggaa aaatggatga cacgatcatc cattcttttt taattctttt tcaaatgtat
     2701 ttgaaagggt agtgaaagtt agcctctcta aagtaagtgg gtgggtaaag gaaagtcgga
     2761 aggcatgaag cataagccgg cttgtctttg atttactatt atagagaggg tctcccagga
     2821 taggaagatt atgatgcaaa aggtgcacac gaatctgatg ggttcgccct gtctttagct
     2881 tgcaatgagc caaggaagtc ttgtttgaga attgctttaa tctgcttaca tgcgtttcag
     2941 catatttccc attttttgca tcaactattc tttttctacg atcatggcga tcacgtccaa
     3001 ttttgtctct gaaaacaagt tcttttctgt tgatatttcc atcaactaga gcccaatatt
     3061 ctctagaaat ctcttttttc tccaataagc gattgagaat gggcaggata aaaggatttt
     3121 tggcaaagag aactaagcca ctggtttcca tgtccagacg atgaacgaca tagcaggttt
     3181 ggccaacata ggtactgaca tggttaagaa gggcaatttc gtttggttga ttaccatgcg
     3241 ttttcatccc ctctggtttg tttacaataa tcaagtgttg atcttgataa acttcctgca
     3301 ctaagtctgg gttgccccaa gggatcgtct tttggggata atcttcctcg tcaaaagtca
     3361 actggcaaac atctccagga tttacgattt cgttccagcg gacttcttct tgatttatca
     3421 aaatatgttt cttgattctc aaaaaatgac ggatttttct agggatgagg agttgttcct
     3481 caagtaattg ctttaccgtc atttgaggta gagaggcggg taatgtaaat gtgaattgca
     3541 tacagatatt gtaacaaaaa aagccctatt tggataggaa atagctaaat tcttgtcttc
     3601 ctatgatgaa gatgataaaa taaacgcatg aaattagata aattatttga gaaatttctt
     3661 tctcttttta aaaaagaaac aagtgaacta gaggactctg attctactat cttacgtcgc
     3721 tctcgtagtg atcgaaaaaa attagcccaa gtaggtccga ttcgaaaatt ctggcgtcgt
     3781 tatcatctaa caaagattat ccttatacta ggtttgagtg caggcttgct agttggaatc
     3841 tatttgtttg ctgtagccaa gtcgaccaat gtcaatgatt tgcaaaatgc cttgaaaact
     3901 cggactctta tttttgaccg tgaagaaaaa gaggctggtg ccttgtctgg tcaaaaggga
     3961 acctatgttg agctgactga catcagtaaa aacttgcaga atgctgttat tgcgacagaa
     4021 gaccgttctt tctataaaaa tgacgggatt aactatggcc gtttcttctt ggctattgtc
     4081 actgctggac gttcaggtgg tggctctacc attacccaac agctggctaa aaacgcctat
     4141 ttatcgcagg atcaaactgt tgagagaaaa gcgaaagaat ttttccttgc cttagaatta
     4201 agcaaaaaat atagtaagga gcaaattcta accatgtacc ttaacaacgc ttattttgga
     4261 aatggtgtgt ggggtgtaga agatgcgagt aagaaatact ttggagtttc tgcatcagaa
     4321 gtgagtctgg atcaagctgc gactctggca gggatgctca aggggccgga actgtataat
     4381 cccttgaatt ccgtagaaga ttctactaat cggcgcgata ctgtcttgaa gaatatggtt
     4441 gcagcaggat atattgataa aaaccaagaa accgaagctg ctgaagttga tatgacttcg
     4501 caattgcacg ataagtatga aggaaaaatc tcagattacc gttacccctc ttattttgat
     4561 gcggtggtta atgaagctgt ttccaagtat aatctaacag aggaagagat tgtcaataat
     4621 ggctaccgca tttacacaga gctggaccaa aactaccaag caaatatgca gattgtttat
     4681 gaaaacacat cgctatttcc gagggcagag gatggaacgt ttgctcaatc aggaagtgta
     4741 gctctcgaac cgaaaacagg gggagttcgt ggagttgtcg gtcaagttgc tgacaatgat
     4801 aaaactggat tccggaattt caactatgca acccaatcaa agcgtagtcc tggttctaca
     4861 attaagcctt tagttgttta tacgccagca gttgaagcag gctgggcttt gaataagcag
     4921 ttggataacc ataccatgca gtataacagc tataaggttg ataactatgc agggatcaaa
     4981 acgagtcgag aagttcctat gtatcaagcc ttggcagaat cgcttaatct acctgctgtt
     5041 gccactgtta atgatttggg tgttgacaag gcttttgagg caggcgaaaa attcggactc
     5101 aacatggaaa aggtcgaccg tgttcttggt gtcgccttgg gaagcggtgt tgaaaccaac
     5161 cctcttcaaa tggctcaagc atacgctgcc tttgcaaatg aaggtttaat gcctgaagct
     5221 cattttatta gtagaattga aaatgctagt ggacaagtta ttgcgagtca taaaaattca
     5281 caaaaacggg tgattgataa gtctgtagct gacaagatga ccagtatgat gttggggact
     5341 ttcaccaacg gtaccggtat tagttcatcg cctgcagact atattatggc agggaaaact
     5401 ggaacaactg aagcagtttt caatccggag tacacaagtg accagtgggt aattggttat
     5461 actccggatg tagtgattag ccactggctt ggctttccta ccactgatga aaatcactat
     5521 ctagctggct ctacttcaaa cggtgcagct catgtcttta gaaacattgc caataccatt
     5581 ttaccttata cgccaggaag tacctttacg gttgaaaatg cttataagca aaatggaatt
     5641 gcaccagcca atacaaaaag acaagtacaa accaatgata atagccagac agatgataat
     5701 ttgtctgata ttcgagggcg tgcgcaaagt ctagtagatg aggctagccg ggctatctca
     5761 gatgcgaaga ttaaggaaaa ggctcaaaca atatgggatt cgatagtcaa tctatttcgt
     5821 taagatgctt gtcaaagcct agctttcttg ttataatgga taagatggag gcgttatggc
     5881 actaaaaaaa gcaagcctag cttgtgcggt ttgtggttcg agaaactatt caatcaagat
     5941 cagcggaaac cccaagccta cacgactaga agtaaataaa ttttgtaagc attgtggcaa
     6001 gtacactaca cacagagaaa cgagatagga gagagcgatg cgttttattg gagatatttt
     6061 tagacttctt aaagacacaa catggccaac tcgcaaggaa agctggagag attttcgttc
     6121 tatcatggaa tacacagctt tctttgtagt aattatttac atttttgacc agttgattgt
     6181 ttcaggtttg attcgattta ttaacatttt ttagaagatt agtggagtta attacactag
     6241 aaatcttcta tttatgaaag gaaatatcat ggatagtttt gataaaggat ggtttgtttt
     6301 acaaacttat tctggttatg aaaataaggt gaaagaaaat ctattacaac gtgcacaaac
     6361 ctacaatatg ttggataata ttctacgcgt tgaaattcca acacaaacag tgcaagttga
     6421 aaaaaatgga aagagaaaag aagtagaaga aaatcgcttt ccaggttatg ttcttgtaga
     6481 aatggtcatg acagatgaag cttggtttgt tgttcgaaac acaccaaatg ttacaggatt
     6541 tgtcggatca cacgggaaca gatcaaaacc aactccatta ttggaacaag aaattcgtga
     6601 cattttggta tctatgggac aaactgttca agaatttgat ttcgatgttg agattggtca
     6661 aactgtacgt attattgatg gtgcttttgc agactacact ggtaagatta cagaaattga
     6721 taataacaaa gtgaaaatga ttatctctat gtttggtaat gacacagttg cagaagtaaa
     6781 cctaaaccaa atcgcagaat tataaccctg agagaggctg gag
//
LOCUS       DAVLBE010000079         6521 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.079, whole genome shotgun sequence.
ACCESSION   DAVLBE010000079 DAVLBE010000000
VERSION     DAVLBE010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6521)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6521)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6521
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.079"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            173..1456
                     /locus_tag="VXB91_001877"
     CDS             173..1456
                     /locus_tag="VXB91_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HEV0471279.1"
                     /translation="MKQESTVDLLLDVDQRPSDGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMIATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLKANWFE
                     IPGFYLPFSTGGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLIGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
     gene            complement(1651..3222)
                     /gene="ffh"
                     /locus_tag="VXB91_001878"
     CDS             complement(1651..3222)
                     /gene="ffh"
                     /locus_tag="VXB91_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HEV0471280.1"
                     /translation="MAFESLTERLQNVFKSLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKALAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTPEERENPD
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(3234..3566)
                     /locus_tag="VXB91_001879"
     CDS             complement(3234..3566)
                     /locus_tag="VXB91_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009660419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HEV0471281.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDNFLQEQIEI
                     LTSIDNRE"
     gene            complement(3657..4034)
                     /locus_tag="VXB91_001880"
     CDS             complement(3657..4034)
                     /locus_tag="VXB91_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HEV0471282.1"
                     /translation="MKIRMRNTIQFDEQLEVIDQLYDVEVHEKGDYSYLLFYNEEKEK
                     VVIKFHGQELVMSRFSNPKTIMRFLKDSDSLAYIPTPMGMQEFIIQTNRYQVDGQKIE
                     LDYQLQNQEGHPFASYQLEITWG"
     gene            4106..5410
                     /locus_tag="VXB91_001881"
     CDS             4106..5410
                     /locus_tag="VXB91_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEV0471283.1"
                     /translation="MNEKVFRDPVHNYIHVNNQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTMTAALLHDLGHGAYS
                     HTFENLFDTDHEAITQEIIQNPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPIENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPEDKDFFARTSPHLLPFFEKNVTLTD
                     YLALDDGVMNTYFQLWMTSPDKILADLSHRFVNRKVFKSITFSQEDQDQLASMRKLVE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESENPRTQIEILQKNGELAELSSLSPIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLHLIENDHFTPNKN"
     gene            5423..6229
                     /gene="yidA"
                     /locus_tag="VXB91_001882"
     CDS             5423..6229
                     /gene="yidA"
                     /locus_tag="VXB91_001882"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HEV0471284.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDQGDYVVTFNGALVQETATGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGTYTVHESTLVSMPIFYRTPEEMAGKEIVKCMFIDEPE
                     ILDAAIEKIPAEFYEHYSINKSAPFYLELLKKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRAMLEVVGNPVVMENGNPEIKKIAKYITKTNDESGVAHAIRTWVL"
BASE COUNT         1854 a         1513 c         1199 g         1955 t
ORIGIN      
        1 ttttttctgc tatactatcc taagcaaagg tttttaatgt catcccgtga ggtgacgaag
       61 acgcagaaat atttgaaact ctttaaagtc tagattttag agaagtctta ctctgagggc
      121 ctattgctgt aaaataatgg gctcttttct gatgcccaaa agtgaggttt atatgaaaca
      181 agaatcaact gttgatttgt tactagacgt tgaccaacgt ccttcggatg gaaaaggaat
      241 tctccttagc ttccaacacg ttttcgccat gtttggtgcg accatcttgg taccattgat
      301 tttgggaatg cctgtatctg ttgccctttt tgcttcaggt gttggaacac tcatctacat
      361 gattgctact ggttttaaag ttccagttta tctaggttct tcatttgcct ttatcacagc
      421 tatgtcactg gctatgaaag aaatgggggg ggatgtatct gctgcccaaa caggggttat
      481 cttgactggt ttggtctatg tccttgttgc taccagcatc cgatttgtag gaacaaaatg
      541 gattgataaa ctcttgccac caatcattat cggtcctatg atcatcgtta tcggtcttgg
      601 acttgcaggt tcagctgtta ccaatgcagg tcttgtagca gacggaaatt ggaaaaatgc
      661 tctggtagcc gttgttactt tcctaattgc tgcctttatc aatacaaaag gaaaaggctt
      721 cctacgaatc attccattcc tctttgccat tatcggtggt taccttttcg cactaactct
      781 tggcttggtt gactttacac cagttcttaa agccaactgg ttcgaaattc ctggtttcta
      841 cttgccattt agcacaggtg gtgcctttaa agagtacaat ctttactttg gtccagaagc
      901 catcgctatc ttgccaatcg ctatcgtaac aatttctgaa catatcggag accatactgt
      961 tttgggtcaa atctgtggcc gtcaattctt aaaagaacca ggtcttcacc gtactcttat
     1021 tggtgacggt atcgcaactt ctgtttctgc cttccttggt ggaccagcca atacaactta
     1081 cggagaaaat acaggggtta tcggtatgac tcgtatcgct tctgtctcag ttatccgtaa
     1141 cgctgccttc atcgcgattg ccctcagctt ccttggtaaa ttcactgcct tgatttcaac
     1201 tattccaaac gctgtacttg gtggtatgtc aatccttctc tatggggtta tcgccagcaa
     1261 tggtttgaaa gtcttgatta aagaacgtgt tgatttcgct caaatgcgaa acctcatcat
     1321 cgcaagtgct atgttggttc ttggacttgg aggagctatc cttaaacttg gtccagttac
     1381 actttcaggt actgcccttt cagccatgac aggaatcatc ttgaacttga tcttgccata
     1441 cgaaaataaa gactaagagt ctaaatacac ctaatccact cagacagctg agtggatttt
     1501 tcgtatatca taataaaagt gtcttaacaa aattattaaa atcaaaaaac gtataatatc
     1561 agatattcta aaaccttgat actgtacgtt ttatcataga aatttttact ttattttctc
     1621 atcaaatgag atttgcatca atctcttgtc ttacttgcgt ttcttcttcg ctttcttcat
     1681 tttgttagcc atacgtttca tggactgttt catggcaaat tcaccaattt tacctttcaa
     1741 accgccacca aacatctggc tcatatctgg cattcctgct cctccgagag ctgataagtc
     1801 aggcataccg ccttgtccca tcattccttc aagggcagac atatccattc ctcccatatt
     1861 tggcatattt ttaggaaggt tatttggatt aatccccatt tgcttcatca ttttattcat
     1921 atccccagac ataacaccct gcatgagctg tttagcctgg ttaaagtcct tgataaattt
     1981 attgacttcg acgaatgtat ttccagaacc agcagcaata cgacggcgac ggcttggatt
     2041 taacaaatct gggttttcac gttcttcagg tgtcatcgaa gacacaatgg cacgtttacg
     2101 agcaatctgg cgttcatcca ccttcatgtt ttgaagtgct ggattgttgg ccatacctgg
     2161 aatcatcttg agcaagtctt ccatcggccc catattttgc acctgatcta attgatcgat
     2221 gaaatcatta aaatcaaagg tgttttcgcg catcttctca gccatttcaa gggctttttg
     2281 ttcatcgtat tcctgagaag ctttctcaat caaagtgagc atatccccca tgccaaggat
     2341 acggctagac atacggtctg ggtggaaggt ttcgatatct gtaatttttt cacctgtacc
     2401 agtgaacttg attggttttc cagtgatgtg acgaaccgat agagccgcac caccacgagt
     2461 atcgccatca atcttggtaa ggatgacccc agtcacttcc aactgagcat taaactcacg
     2521 cgcaacattg gctgcttcct gaccaatcat ggcatcaacg acgaggagaa tttcatttgg
     2581 ttgagccaat gctttcacat cacgaagctc attcatgagg agctcatcaa tttgcaaacg
     2641 acccgcagta tcaatcaaga catagtcgtt atgattagtt tgggcttgct ccaaaccttg
     2701 acgtacaatc tcaacagctg gtacttctgt tccaagtgca aagacaggca catcaatctg
     2761 ttgtcccaaa gtcttaagct ggtcaatggc agctggacga taaatatccg ccgcaatcat
     2821 caaaggacga gcattttctt ctttcttgag tttgttggcc aatttaccag caaaggttgt
     2881 tttaccagcc ccttgtaaac caaccatcat gatgatggtt ggaatcttag gtgacttgat
     2941 aatttctgcc gtatcagaac ctaaaacggc tgtcagttcc tcatcaacga ttttaataat
     3001 ctgttgcgca ggattaagtg tatcaatgac ctcatgcccg actgcacgct cacgaacttt
     3061 cttgataaag tcctttacaa caggcaaagc aacgtcggcc tcaagcaagg ccaagcgaat
     3121 ttctttggtt gcctcttgga catcagattc agagattttt ccttttttac gtagactttt
     3181 aaagacgttc tgcaaacgtt ctgttaaact ttcaaatgcc atttttcttc ctcttattct
     3241 ctattatcaa tgcttgttaa aatttctatc tgctcctgca gaaagttatc cttgggatag
     3301 cgctccaaaa tctgatcaaa aatctgactg cggacaatat agtccgagta catgtgcaat
     3361 ttcatctcat aatcttccag aatcttttct gttcgcttga tattgtcata gacagcctga
     3421 cgactgacac cgaactcctc ggcaatttca gcaaggctgt aatcatcagc gtagtagagc
     3481 tcgatataat tcatttgctt atctgtcaaa agcgccgcat aaaattcaaa gagcgcattc
     3541 atacgattgg ttttttcgat ttccataact tttattatac caaaaattag cctaatctac
     3601 cacactagga agccgatcca agaagataga tagctaaatt tgaaaaagac ataagcctag
     3661 ccccaagtaa tttccaattg atagctggca aagggatgtc cctcttgatt ttgtagttga
     3721 taatctagtt caatcttttg cccatccact tgataacgat tcgtttggat aataaactcc
     3781 tgcataccca taggtgtggg aatataggct aaactatcac tatcctttag aaagcgcata
     3841 atggtcttgg gattggaaaa tcgactcatc acaagttctt gaccatgaaa tttaatcact
     3901 actttttcct tttcctcatt atagaaaagc aggtagctat aatctccttt ttcatgcact
     3961 tccacatcat aaagctggtc aatcacttcc aactgctcat caaactgaat tgtatttcgc
     4021 atccgaatct tcacatcagg ccctctttct tgtctcttgt cctactattt taccaaaaag
     4081 agcaggattt tgctataatg gtcatatgaa cgaaaaagta ttccgtgacc ctgttcacaa
     4141 ctacatccat gtcaataatc aaatcatcta tgacttgatt aatacaaaag aatttcagcg
     4201 tttgcgccgg atcaaacaac tgggaacttc cagttatacc ttccacggtg gagaacacag
     4261 tcgcttctct cactgtctag gagtctatga aattgcacga cgcatcacag agattttcga
     4321 agaaaaatat cctgaggaat ggaatcctgc cgagtctctc ttgaccatga ccgctgctct
     4381 cctacacgac cttgggcatg gtgcctactc ccatactttt gaaaatctct ttgatacaga
     4441 ccatgaagcc attactcagg agattattca aaatcctgag acagagattc accaagtcct
     4501 gctacaagtg gcacctgatt tcccagaaaa ggtggccagt gtcattgacc atacctatcc
     4561 taataagcag gtcgtgcagc tcatttctag tcagattgac gcagatcgca tggactatct
     4621 cttgcgcgac tcctatttta caggagcatc ctatggggaa tttgacctga ctcgaatcct
     4681 ccgagtcatt cgtcctatcg aaaatggtat cgcctttcag cgcaatggca tgcacgccat
     4741 cgaagactac gtcctcagtc gctaccagat gtacatgcag gtttatttcc accccgcaac
     4801 acgcgccatg gaagttctcc tacagaatct tctcaaacgc gccaaggaac tctatcctga
     4861 ggacaaggat ttctttgccc gaacttctcc acacctcctg cctttcttcg aaaaaaatgt
     4921 gaccttgact gactatctgg ctctggatga tggcgtgatg aatacctact tccagctttg
     4981 gatgaccagt cctgacaaga ttcttgcaga tttatcgcat cgctttgtca accgcaaggt
     5041 ctttaaatcc attacctttt cacaagaaga ccaagaccaa ctcgctagca tgagaaaatt
     5101 ggttgaggac atcggctttg atcccgacta ctatactgcc attcataaga actttgacct
     5161 cccttatgat atttaccgtc ccgaatctga aaatccaagg acacagattg agattttaca
     5221 aaaaaatgga gaactggcag aactctctag cctgtcccct atcgtccaat cccttgctgg
     5281 aagtcgccac ggagataatc gcttttattt cccgaaagaa atgttagacc aaaacagcat
     5341 cttcgcaagc atcacccagc aatttttaca cttgattgag aacgatcatt ttaccccaaa
     5401 taaaaactaa aagaggaaat ttatgagtat taaactaatc gccgtcgata ttgacggaac
     5461 cctagtcaac agccaaaagg aaatcactcc tgaagtcttt tctgccatcc aagatgccaa
     5521 agaagctggt gtcaaagtcg tgattgcaac tggccgcccc atcgcaggtg ttgccaaact
     5581 tctggacgac ttgcagttga gagaccaagg tgactatgtg gtgaccttca atggtgccct
     5641 tgtccaagaa actgctactg gccatgagat tatcagcgaa tccttgacct atgaggatta
     5701 tctggatatg gaattcctca gtcgcaagct cggtgtccac atgcatgcca ttaccaagga
     5761 cggtatctat actgcaaatc gcaatatcgg aacatacact gtacacgaat caaccctcgt
     5821 cagcatgcct atcttctacc gtacccctga agaaatggct ggcaaggaaa ttgtcaagtg
     5881 tatgttcatc gatgaaccag aaattctcga tgctgcgatt gaaaaaatac cagccgaatt
     5941 ttacgagcac tactctatca acaaatctgc tcctttctac ctcgaactcc ttaaaaagaa
     6001 tgtagacaag ggttcagcta ttactcactt ggctgaaaaa ctcggattga ccaaagatga
     6061 aaccatggca atcggtgacg aagaaaatga ccgtgccatg ctggaagtcg ttggaaaccc
     6121 cgttgtcatg gaaaatggaa atccagaaat caaaaaaatc gccaaataca tcactaaaac
     6181 aaatgacgaa tccggcgttg cccacgccat ccgaacatgg gtactgtaaa agtatcattt
     6241 ttcaataaga attgattagc aataaaatcc aatgaatttt tttagcaaac tatttaattt
     6301 aaaacaaaat aatcataata gagacacaaa ttctgattgt aacaattttt acctaaacga
     6361 tttagaatgt ggccttactc ctgggcaact catactcata gattggactc aaaaaacagg
     6421 gagaaattat aatttcccaa gatattttaa atactctctt caaattgacc ctgaatctac
     6481 acacaatcaa ttatacaaat taggatactt cactaaaaat a
//
LOCUS       DAVLBE010000080         6054 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.080, whole genome shotgun sequence.
ACCESSION   DAVLBE010000080 DAVLBE010000000
VERSION     DAVLBE010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6054)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6054)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6054
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.080"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            137..902
                     /locus_tag="VXB91_001883"
                     /pseudo
     CDS             137..902
                     /locus_tag="VXB91_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812989.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            918..1397
                     /locus_tag="VXB91_001884"
     CDS             918..1397
                     /locus_tag="VXB91_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0471285.1"
                     /translation="MKLNKQKNRMIYVLSNFLYAISVSIIYALNGIVLLVIVSKLGIP
                     GDLGLDFIVAIVVNTILLVLFYFLLSYIFYLYKLKSGLVFGILVALLLFIPNILNTMM
                     MNTSNDLFIKAIELLPFYSLPVFVASNTMSISQYLVVITTIILLYFFTLKKSKKYSF"
     gene            1783..1992
                     /locus_tag="VXB91_001885"
     CDS             1783..1992
                     /locus_tag="VXB91_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0471286.1"
                     /translation="MAKNLKLKLARVERDLTQGQLAEAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
     gene            1982..2470
                     /locus_tag="VXB91_001886"
     CDS             1982..2470
                     /locus_tag="VXB91_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0471287.1"
                     /translation="MKNRFYYYQLLDEREEQLFNKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYIIYLPWIFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            2586..4046
                     /locus_tag="VXB91_001887"
     CDS             2586..4046
                     /locus_tag="VXB91_001887"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HEV0471288.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIHNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEDLRFSDSDIAYLESLGYHGAFLDYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGDQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DETGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISDMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            4043..4867
                     /gene="nadE"
                     /locus_tag="VXB91_001888"
     CDS             4043..4867
                     /gene="nadE"
                     /locus_tag="VXB91_001888"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HEV0471289.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGRLAQLAMEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            5217..5768
                     /locus_tag="VXB91_001889"
     CDS             5217..5768
                     /locus_tag="VXB91_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0471290.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSAENLTYVTWD
                     PHPDIEITRNSIRNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGHGMMTEALKAILDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
BASE COUNT         1890 a         1024 c         1295 g         1845 t
ORIGIN      
        1 ttaaactcaa taagaatcaa agagcaaacc atgaatatta atggaggaat aaaaaatgta
       61 agttataaat gtaagtaagc attatggtca ttcaatcatt ctcaaagata taaattttgc
      121 acttaacaag ggtgaaattg ttggtctagt agggagaaat ggagttggta agagtacgtt
      181 gatgaaaatt cttgttcaaa ataatcaacc gacttcaggt aatattataa acagtgataa
      241 tgttgggtat ttaatcgaag aaccaaaatt atttttatct aaaacaggtt tagagaattt
      301 aaaatatttg tcaaatttat atggtgttga ctacaatcaa gaaagattta gaagtttgat
      361 ccaagagtta gatttgactc agtctattaa taaaaaagta aagacctatt ctttgggtac
      421 aaaacaaaaa ttagctttgc ttctaactct cgttacggaa cctgatatat tgattttaga
      481 tgaaccgact aatggtttag atattgaatc atcacaaata gttttagcgg ttctaaaaaa
      541 aattagcttt aaatgaaaac gtgggaattt taatatcgag tcataaatta gaagacattg
      601 aagaaatttg tgagagggtt cttttcttgg agagcgggct tttgacattt caaaaagtag
      661 gaaaagatag tcataatttc ttgtttgaga tagctttttc atcagctaca gatagagaca
      721 ttttcattac caaacaagaa tttggggata ttgttcagga agagggattg agaattacta
      781 tgtctgggaa tattcaaaat agtgagcttt ttaaattttt taacgaaaac tctattaaag
      841 tagttgattt tgaaactaaa aaagagacgc ttaaagatat ttacctaaat cgttcaaaat
      901 aaaggaaggt tataatcatg aaattaaata aacagaagaa tcggatgatt tacgtcttgt
      961 ctaattttct atatgccatc tcagtttcca ttatttatgc tttgaatggc attgtgttac
     1021 tagtcatagt aagtaaattg ggtattccag gtgatttagg attagatttt atagtagcta
     1081 ttgtagtcaa tacaattttg ttagtcctgt tttattttct attatcttac attttttatt
     1141 tatacaaatt gaaaagtggc ttggtatttg gtattttagt agctttacta ctctttatcc
     1201 ctaatatatt aaatacgatg atgatgaata ctagtaatga tttgtttatc aaagcaattg
     1261 aacttcttcc tttttattct ttacctgtat ttgtggcttc aaatacgatg tctattagtc
     1321 agtatcttgt ggtaatcact acaatcattt tattgtactt tttcactctc aagaaaagca
     1381 agaagtattc attttagttt catttagtat tattttgcat acctaaaata caataaaaaa
     1441 atcagtcatc ttggtatgct cctgctttca ctattcaaca cgtttttgac ttatactagg
     1501 ctcatttcca aaagcattat ataatagtga tatgaaacca actaaactaa acaagaaata
     1561 taagcaataa aaactcgttt aaaagatcct actaaagcta atactaaata aaaataaaag
     1621 agtaaactag gaagtttatt tcaaacaacc taaaatactg attttcggct gaagataata
     1681 ctggagtgca aattaatggg gttataataa atagctgata gcttgtgttg gttttggatt
     1741 ttttaagagt agatgagtat taaaactata aggaggacga aggtggctaa aaatttaaaa
     1801 ttaaaattag ctcgggtaga gcgtgattta acacaaggtc aactggcaga ggctgtcggg
     1861 gtgacgcgcc agactattgg tttgatagaa gcggggaaat acaatcccag tctctcgctc
     1921 tgccagtcca tttgcagatg tttagggaaa accctagacc aactattttg ggaggaagaa
     1981 gatgaaaaat agattttatt attatcaatt actagacgaa agagaagaac aactgttcaa
     2041 taaagcgggc tctgaaagtt tctatatctg catcgctttg tcgctcctat cttatatcat
     2101 ttcagtatta gcaccaagcc tttttaattc taatatgctg ctaatcgtta tcatcatagg
     2161 gacattttac tttttcaatc gtgcccgtta tctgggagtg acctactata gtcgttttca
     2221 ttttacgatt ttgggttgtt ttttcctaac cttggctatt acggctcttt tgatgttgca
     2281 gaattatcaa ttcaacatag aaatttatca gcacaatcct ttgaatttta aatacctgtc
     2341 tgcttgggtc attacttata tcatttacct tccgtggatc tttattggca atcttggtct
     2401 taagagctat ggcgaatggg ctcagaaaaa atttgaacaa gatatggatg aattggagag
     2461 tggagaatag cttgttactc ttttctcaat ccagctaaaa tgtgatataa tagtactaat
     2521 ttattggaat acatgaaagt tcttgaaaat tttcatgggt ttctagctaa ggaagtagga
     2581 aaagtatgta tccagatgat agtttgacat tgcacacgga cttgtaccag atcaacatga
     2641 tgcaggttta ctttgaccaa gggattcaca ataagaaggc ggtctttgag gtgtatttcc
     2701 gccaacagcc ttttaagaac ggctatgcgg tttttgcagg tttggaaaga attgtgaact
     2761 atcttgaaga cttgcgtttt tcagatagtg atatagccta tttggagtcg cttggttatc
     2821 atggggcgtt cttggattac cttcgcaatt tcaagttgga gttgaccgtt cgttctgccc
     2881 aagaagggga tttggttttt gctaatgaac cgattgtgca ggtggaagga cctctagccc
     2941 aatgtcagtt ggtcgaaacg gctcttttga acatcgtcaa ctaccagacc ttggtggcga
     3001 cgaaggcagc tcgtattcgt tcggttatcg aagatgaacc cttgatggag tttgggacac
     3061 gtcgggctca agaaatggat gcggccatct ggggaacacg cgcagctgtg attggtggcg
     3121 ccaatggaac tagcaacgtg cgtgcgggta agctctttga cattcctgtt ttgggaaccc
     3181 atgcccatgc cttggtacag gtttatggca atgactatga agctttcaag gcttacgctg
     3241 cgacccacaa aaattgtgtc tttcttgtgg atacctatga cacccttcgc atcggtgtac
     3301 cagctgccat tcaggtggcg cgtgagctgg gtgatcagat taactttatg ggtgtgcgga
     3361 ttgactctgg ggatattgcc tacatttcta agaaagtccg tcagcaactg gacgaggctg
     3421 gatttacaga ggctaagatt tatgcttcta atgatttgga cgaaaatact atcctcaatc
     3481 tcaagatgca aaaggccaag attgatgtct ggggcgtggg taccaagctg attacagcct
     3541 atgaccagcc agctcttggt gcagtttaca agattgttgc aatcgaagat gaaactggtc
     3601 agatgcgcaa tacgattaag ctgtctaata atgctgaaaa agtttctacg ccaggtaaga
     3661 agcaggtgtg gcgcattacc agtcgtgaaa aaggcaagtc agaaggcgac tatatcactt
     3721 atgatggtgt ggatattagc gacatgacag aaatcaagat gttccatccg acctatacat
     3781 acatcaagaa gacggttcgt aattttgatg ccgttcctct cttggtggat atcttcaaag
     3841 aaggaatatt agtttacaac ttgcctagtt tgactgacat tcaggattat gcccgtaaag
     3901 aatttgacaa gttgtgggat gagtataagc gtgtgctcaa tccgcagcac tatccagtgg
     3961 atttggcgcg tgatgtatgg caagataaga tggacttgat tgataagatg cgcaaggaag
     4021 cccttggtga aggagaagaa gaatgagttt gcaagaaacg attatccaag agctgggtgt
     4081 caaaccagtg attgatgccc aggaagaaat ccgtcgttct attgatttct taaaaagata
     4141 tctgaaaaaa catcccttcc taaaaacctt tgtactaggg atttctgggg gacaagactc
     4201 aaccttggca gggcgtttgg cgcaattagc tatggaagaa ctgcgagctg aaacgggaga
     4261 cgatagctac aaatttatcg ctgtccgcct gccatacgga gtgcaagctg atgaagcaga
     4321 tgctcaaaaa gctctagcct tcatccagcc agatgtcagc ttggttgtga atatcaagga
     4381 atcagctgat gccatgacag ctgcagttga agcgacaggt agtcctgttt cagacttcaa
     4441 caaggggaat atcaaggcac gttgccgtat gattgctcag tatgcccttg ctggttccca
     4501 tagcggagcg gtcattggaa cagaccacgc cgcggaaaat atcacaggtt tctttaccaa
     4561 gtttggtgac ggcggtgcgg atattctccc tctttaccgc ctcaataaac gccaaggaaa
     4621 acagctcttg cagaaacttg gcgcagagcc agccctttat gaaaaaatcc caacggcaga
     4681 cctagaagaa gataaaccag gcctagctga cgaagtcgca cttggagtca cctacgcaga
     4741 gattgacgac tacctagaag gcaaaacaat cagcccagaa gctcaagcga ccattgaaaa
     4801 ctggtggcac aaaggccaac acaaacgcca cttacccatc actgtatttg atgacttttg
     4861 ggagtaaaaa ggtccggggg acctttttag cttcttgccc tgaaattaaa aagcaagaaa
     4921 aacctccact ggaggttttc agcctctcat cttaaaataa gaaagtgaga gaaggtctgg
     4981 gggatcttga accccgagtt tagaaataag aaaatgaggc agattcggta actcgaagag
     5041 ttcgatttca tcgtcttacc cctgcaacga tgactaggtt tgaaaaagct tgctagatcg
     5101 catttcaaac caggcagcga ttgcgtcaag aaattagaag acaaactcgt tttctagctg
     5161 ttactgagtt gagccttttt actacgagca tagaaataag gaagtgaggt agcatcatga
     5221 aatctattgg tacgcaaata ttacagacag aacgtttgat tttaagaaga tttgtggaga
     5281 gtgatgcaga agctatgttt caaaattggg cttcatccgc tgagaatctg acctatgtta
     5341 cctgggatcc ccatcctgat atcgaaatca ctcgaaactc gattcgcaat tgggttgctt
     5401 cctatactaa tctcaactat tataaatggg ccatttgtct aaaagaaaac ccagagcaag
     5461 tgataggaga tatcagcatt gttaagatag acgaggctga tttaagctgt gaaatcggct
     5521 atgtgctagg caaggcttac tggggacatg gtatgatgac agaggccttg aaagctatct
     5581 tggacttttg ttttactcaa gcaggttttc aaaaggtcag agcacgttat gccagtctca
     5641 acccagcttc aggtcgtgtc atggaaaagg ctggaatgtc ctatctacaa accattgtta
     5701 atggtgtaga gagaaaaggc tatcttgcgg atcttattta ttatggtata agtagggaag
     5761 aatgttgaat tctattttct gtttctatcg aagtcaacta tttattgtaa atataataat
     5821 tagcattcca agtttatttg aaactttaaa atagcatatt gattagtaca agacagatgt
     5881 tctagttcct tctttaatct ggtttagtat tagttaaaaa atcgctttaa gcttgtaact
     5941 aagagggacc taatcgacta gattctccag ccgaacaggt ggtaatgtac tttttatagt
     6001 gtaatcctag ctgttgttaa atttaaaata gaatcctcta tcgagttagg gaat
//
LOCUS       DAVLBE010000081         5911 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.081, whole genome shotgun sequence.
ACCESSION   DAVLBE010000081 DAVLBE010000000
VERSION     DAVLBE010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5911)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5911)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5911
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.081"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(<1..693)
                     /locus_tag="VXB91_001890"
     CDS             complement(<1..693)
                     /locus_tag="VXB91_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-binding factor A"
                     /protein_id="HEV0471291.1"
                     /translation="MSDVKEEVSSLSEKQLRQIDVEYAELNDSDIIERLAYLEINNNE
                     KRIVISDIEPTKEIMSVSDQIFEIQKNFQKIKNMFELFISDVSDFLSIKNKLESKELE
                     IEEADVNRFMIHLLSSGKLFVDFNENQIKQKYSKDSEEFDCIHGFASYQYDTNFAYRF
                     CHSLRNYSQHTDLPINEVKAVSPDDETVIIDFYIDLDYLLNSNFKWKKLKGELIKLNQ
                     ETSKIDAIALVKE"
     gene            complement(695..1252)
                     /locus_tag="VXB91_001891"
     CDS             complement(695..1252)
                     /locus_tag="VXB91_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0471292.1"
                     /translation="MARTELPDQIETERLVLRVRTVADAEDIFDYASLPEVAYPAGFP
                     PVKTLEDEIYYLEHILPERNQKENLPAGYGIVVKGTDKIVGSVDFNHRHEDDVLEIGY
                     TLHPDYWGRGYVPEAARALIDLAFKDLGLHKIELTCFGYNLQSKRVAEKLGFTLEARI
                     RDRKDAQGNCCDSLIYGLLKSEWEE"
     gene            complement(1239..1688)
                     /locus_tag="VXB91_001892"
     CDS             complement(1239..1688)
                     /locus_tag="VXB91_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase"
                     /protein_id="HEV0471293.1"
                     /translation="MIGVVARENAAEQIKQYQKFTVNISDETSMLAMEQAGFISHQEK
                     LERLGVHYEISERTQTPILDACPLVLDCRVDRIVEEDGICHIFAKILERLVAPELLDE
                     KGHFKNQLFAPTYFMGDGYQRVYRYLDKRVDMKGSFIKKARKKDGKN"
     gene            complement(2101..2496)
                     /locus_tag="VXB91_001893"
     CDS             complement(2101..2496)
                     /locus_tag="VXB91_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEV0471294.1"
                     /translation="MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQSAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASDFK
                     NWTEKELLALKGIGPATIKKLKENGIKFK"
     gene            complement(2592..2846)
                     /locus_tag="VXB91_001894"
     CDS             complement(2592..2846)
                     /locus_tag="VXB91_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HEV0471295.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKAGKGFHDLPEGLFGERNY"
     gene            complement(2856..4190)
                     /locus_tag="VXB91_001895"
     CDS             complement(2856..4190)
                     /locus_tag="VXB91_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HEV0471296.1"
                     /translation="MADERIHVLRDILLELHNGASPESVQERFDATFAGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVSDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYESMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTIAKSLPEVSISSVKEAFEAFATEFESMIFKEESIL
                     LMILLESFTQDDWLQIAEESDAYGYAIIRPSEKWVPERQSFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKDDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKTIMKGLREGTKDKY
                     EMWFKSESRGKFVHITYAAVHDEDGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            complement(4190..4423)
                     /locus_tag="VXB91_001896"
     CDS             complement(4190..4423)
                     /locus_tag="VXB91_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HEV0471297.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLAGTPMDKIVRTLEANGYEVIGLD"
     gene            complement(4691..4879)
                     /locus_tag="VXB91_001897"
     CDS             complement(4691..4879)
                     /locus_tag="VXB91_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0471298.1"
                     /translation="MRLGGSLGQRRENEIFFGLLAILFIKPIIGIVKFFWMIISFAVQ
                     LLFYKILFKILDWLFKLI"
     gene            complement(4839..5021)
                     /locus_tag="VXB91_001898"
     CDS             complement(4839..5021)
                     /locus_tag="VXB91_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0471299.1"
                     /translation="MNPIKAFDKIYGNYFLTVQGVKVMKTIKKADHVVVGLGKLFIAD
                     KLMDTARWLIRPEERE"
     gene            complement(5023..5802)
                     /locus_tag="VXB91_001899"
     CDS             complement(5023..5802)
                     /locus_tag="VXB91_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0471300.1"
                     /translation="MAEQDLAMQVLQQVVKLPVVKVDRSKFLVDKFSKELDPKDIPTL
                     LEQGTTTLLSQEILDRVANACIRDNVLLASGTSVLAGLAGGLAMAITIPADVAQFYAF
                     SLKLAQELGYIYGYEDLWASREELSEDAQNTLLLYLGVMLGVNGTAALLCAGGITIAK
                     QVMKTVPNKALTKTLWYPILKKVLKIFGVNLTKGGLAKGIGKFIPILGGIIAGGLTFA
                     TMKPMGESLQKELSKLVNYSEVQYQEDVETIRKEAEIIKGE"
BASE COUNT         1727 a         1349 c         1021 g         1814 t
ORIGIN      
        1 ttctttcact agagctatag cgtcaatctt agatgtttct tggtttagtt ttatcaactc
       61 ccctttcaat tttttccatt taaagttgga atttaaaaga taatctaaat caatatagaa
      121 atctattata acagtctcat catctgggct aacagctttt acctcattta ttggtaagtc
      181 agtatgttgc gaataatttc tcaaagaatg gcaaaatcga taagcaaaat tggtatcata
      241 ctgatagctt gcaaaaccat gtatacaatc aaactcctca ctatctttgg aatatttttg
      301 tttaatttgg ttttcgttaa aatcgacaaa caattttcca ctggataata aatgaatcat
      361 gaaacgattt acatctgcct cttcaatttc taattccttt gactcaagtt tatttttaat
      421 acttaaaaaa tccgagacat ctgaaataaa caattcgaac atattcttga ttttttgaaa
      481 attcttttga atctcaaaaa tttggtccga gactgacatt atttccttgg ttggttcaat
      541 atcagagatg acaatacgtt tttcattgtt gttaatttct aaataagcta atcgctcgat
      601 aatatcacta tcatttaatt cagcatactc aacatcaatt tggcgtaact gcttctcaga
      661 tagagagctt acttcctctt ttacatcgct catcttattc ctcccactcg ctcttcagca
      721 agccatatat cagactgtca cagcagttgc cttgagcatc tttgcggtct cttatgcgag
      781 cttcgagggt aaagccaagc ttttccgcga ctcgtttact ttgaaggtta tatccaaagc
      841 aagttagttc aatcttgtga agacccaaat ctttaaaggc taagtcaatc aaggcacgcg
      901 cagcttctgg cacataacct cgcccccaat agtctgggtg taaggtatag ccgatttcca
      961 gcacatcatc ttcatggcga tggttgaaat cgacagagcc aacgatctta tccgttcctt
     1021 tgacgacaat cccgtagcct gctgggagat tttccttttg attacgctcc ggaagaatgt
     1081 gctccagata ataaatctca tcttccaagg tcttgactgg aggaaaacct gctggatagg
     1141 cgacctctgg caaactagca tagtcaaaga tatcctcagc atccgccaca gtacggactc
     1201 gtaaaacgag acgttctgtt tcgatttgat ctggcagctc agttcttgcc atccttcttc
     1261 ctcgcttttt tgatgaaact gcccttcata tctacacgct tatccagata gcgataaacg
     1321 cgctgatatc catctcccat gaaataggtt ggggcaaaca gttgattttt aaaatgtccc
     1381 ttttcatcca ggagttctgg ggcaacaagt cgctcaagaa tcttggcaaa gatgtggcaa
     1441 ataccgtctt cctcaacaat cctatctacc ctacaatcta aaacaagtgg acaggcgtct
     1501 aaaataggag tctgagttcg ttcagaaatt tcataatgca ctcccaaacg ttccaatttc
     1561 tcctgatgac tgataaaacc agcctgctcc atcgcaagca tagaagtttc atcagaaata
     1621 ttcacagtaa atttttgata ctgtttgatc tgctctgcgg cattctctct cgcaacgact
     1681 ccaatcacaa cccaatctcc tagactataa gaggaactac aggtcgtgat gttatagcca
     1741 aaattctaat cttgatatcc taaaataaaa acaggaaaac cataatatag tttacttgtg
     1801 ttaaaagatt gcttcataac aacccccttt gactaagacg taaaagaaaa gccctgccat
     1861 ctacatgaca gggacgaatg tgtttatccg cggtaccacc caatttcggg cagttgcccg
     1921 caactctcgt ctttaaagca aaaagacact tttatttcat tttttcagtc attagcaacc
     1981 agttttgaca catttgtgga cttctcagcg ccgccacttt ctgtaaaatg tgggattcaa
     2041 aacacctcta atggctctat tgtagcaagt ttttctcgga aatgcaaggc tcaagaaaaa
     2101 ttacttgaac ttgatgccat tttctttcaa tttcttgatg gtagctgggc cgattccttt
     2161 caaggcaagg agttcttttt cagtccagtt tttgaaatct gaagcagact tgattccttc
     2221 atcatagaaa gtcttggcac gatcaagtgg aagtccaccc aagtttgctg caaaatcttc
     2281 tacagaatta gctacttttt gagcttgctc tttggtagct tctactgctt gttcaacttt
     2341 tttagaaaca gccttaccag ctgcgcttgc tgactgttct gcacgcttca cgactttttt
     2401 tgtctcatct acaaccttag tcacagtact tgaaaaggca cctgcgcgac ggaggccatt
     2461 tcgtaattgt tttttacgat tgagtttctt tgacatgata aaatcctttc aataaaaaat
     2521 ccctgctctg acaaggattt aacataaaca ttctatcaag attttagtga aaaatcaaga
     2581 atctttctcg tttaataatt tcgctcacca aacaagcctt ctggcaaatc atggaatccc
     2641 ttgcctgctt tgaagttttc aaacttacca agcaagaact gataagcatc caagcgactc
     2701 tcgtagcgaa tcatggcatc tttggcacgc tcgtcctggt cttcttcgta aactttttga
     2761 ctttccttgt gcgccatgtc gttaatcatg atttgggtat tgacccaagc ttcaaattcc
     2821 ttcataaatt cttgttcgta actcattttt tctccttatt ctaatccacg aaaatagtcc
     2881 gtatcaatct cacggtaggg ctggatatcc tgaacatact ccaacactcc ttggaattct
     2941 ccgtcttcat cgtgtactgc agcataggtg atgtggacaa acttacctcg cgactcagac
     3001 ttgaaccaca tttcatactt gtccttggtc ccctcacgaa gccccttcat gatagttttg
     3061 accttgtcca agtacttagg cggatggcag agttcgacat tgcgcccgac ttgagacggc
     3121 gtccgtttga aaatcatctc atcagctggc gtattgtcat tgtaatactg gaaaatatca
     3181 tctttattga caaaggtaat ctccataggg aggtgattga ggatgagatt ggcctgctcg
     3241 actgaaagat agccattacc aaaagcctgt tgactatggc ggtccagcac agcttccttt
     3301 tccttagggg taaaggtaat ggtaaaatgg ccttctggcg tatctatgac ttgttgaact
     3361 tgaccttctg ccgtatctag ctgtacaggc tcctctgcaa tcttttcctc aataaagctc
     3421 tgtcgttctg gcacccattt ctctgacgga cggatgatgg catagccata ggcatcgctc
     3481 tcctccgcaa tctgaagcca gtcatcctga gtaaaagact caaggagaat catgaggagg
     3541 atggactctt ccttgaaaat catactttca aactctgtcg caaaagcttc aaaagcttcc
     3601 tttacactgc taattgacac ttctggtagt gacttggcta tcgttagagc tgtttgaaag
     3661 agttccctaa tctgatcatc cactccccac ataactttgg gaggtgaatc gtgtccatag
     3721 cgctccatga taggaaagaa gagttcttcc ttacgttggt aatggatgtc aaattgaccc
     3781 acaagtccca tctgacgcac caaaccctta cgcatctccg ccagcatttc ctcgtcttcc
     3841 atagactcat aggtatctaa caatctacga atgcgaatca aggccgcacg gagagccaga
     3901 ttttcttctt tgaagacacg aactgggtga cctggatgct cagtatctga aacttcgaca
     3961 cctttgatag catttttaaa aagattggca tggacatcac agagttccat aacatcttca
     4021 aaggtgacac ctgagtctga gttcatcagc tcgtgctcca taagggaaat ctcaatggct
     4081 gagacacccg caaaggtcgc atcaaaacgc tcctgaaccg actcaggaga ggcgccatta
     4141 tgcaattcta ataaaatatc ccgtaggaca tgaatccgtt catctgccat tagtctaatc
     4201 caatcacttc gtagccattc gcttccagtg tgcgtacaat cttgtccata ggagttcctg
     4261 ctagcttaga accttgttta agtgatactt tacgaccaac tgtattgcgc atcaagggat
     4321 tggcaagggg tttaaaaccc agctccacta gaatttccaa gacttctgga tgcttgtcca
     4381 ccacttctgc aacaggaatt gacacatcga tgatattgtc catgacgacc tccattatat
     4441 gttctaatac tcaatgaaaa tcaaagagca aactagaaag ctagccgcag gttgctcaaa
     4501 acaccgtttt gaggttgtgg atagaactga cgaagtcagt aacatatata ctgcaaggtg
     4561 aagctgacgt ggtttgaaga gattttcgaa gagtataaaa tgattttact gcttatatta
     4621 taccatatgg agagagatta aaaaactagc agtggagttc ctgctagctc tctgcgactt
     4681 ggattaccat ctagataagt ttaaagagcc aatccaatat cttaaataat atcttgtaaa
     4741 acagcaattg aactgcaaag gaaatgatca tccaaaagaa tttcacaatc ccaataatcg
     4801 gtttgataaa aagaatagca agaagaccaa aaaaaatttc attctctctc ctctggccta
     4861 atgagccacc gagccgtatc cattagctta tctgcaataa aaagttttcc cagaccaaca
     4921 acgacatggt cagctttctt tatcgttttc atcactttta caccttgcac ggtcaaaaag
     4981 taattaccat aaattttatc aaaagctttg ataggattca tattactctc ctttaatgat
     5041 ttcagcctct tttcggattg tttcaacatc ttcttgatat tgaacttcac tatagttgac
     5101 tagcttggat aattctttct gcaagctttc ccccattggt ttcatagttg caaaggttaa
     5161 accacctgca atgataccac ccaagatagg aataaatttc cctattcctt tggccagccc
     5221 tcccttggta agattcacac caaatatttt taagactttt ttcaaaatag ggtaccaaag
     5281 cgtctttgtt aaagctttat taggcactgt tttcattacc tgtttggcaa ttgttatacc
     5341 accagcacat agcaaagcag cggttccatt cacccctaac attacgccta gataaagcaa
     5401 gagggtattt tgagcatctt cactcaactc ctcgcgtgaa gcccaaagat cctcataacc
     5461 ataaatataa cctaattctt gagccaattt cagagagaaa gcataaaatt gagccacatc
     5521 agctggaatg gtaattgcca tagcaagccc tccagctaat cctgccaaaa cagaagtccc
     5581 actcgctaat aatacattgt cccgaataca agcattagct acacgatcta atatttcttg
     5641 agatagaaga gtcgttgtac cttgttccaa taaggtagga atatcttttg gatccaattc
     5701 tttggaaaac ttatccacta aaaatttcga acgatcaacc ttaacaacag gtagtttcac
     5761 cacttgttgc aatacttgca tagctaagtc ttgttcagcc atatacaaac tccttatttc
     5821 ttttttacac cttatcatat tatatttcct acaaaaaaag cattttctaa ttagataaca
     5881 ttaaaaaata cagaacccct tttttatagt a
//
LOCUS       DAVLBE010000082         5319 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.082, whole genome shotgun sequence.
ACCESSION   DAVLBE010000082 DAVLBE010000000
VERSION     DAVLBE010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5319)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5319)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5319
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.082"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            <1..1636
                     /locus_tag="VXB91_001900"
     CDS             <1..1636
                     /locus_tag="VXB91_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0471301.1"
                     /translation="KFLDKLIINSNLSGAESIALKSVITLTSGAIFYFVSGMFSHILG
                     FRLETNLRKRGIDGLEKASFRFFDLNPSGQIRKIIDDNAAQTHQVVAHMIPDSSQAII
                     TPVLVLALGFIVSIRVGIILLALTIIGGLILGAMMGEQEFMKIYQESLSKLSAETVEY
                     VRGMQVVKIFKANVESFKSFYKAIKDYSKYAYDYSLSCKRPYVLYQWLFFGLIAILII
                     PIVYFMTSLASAKVILLELIMILFLSGVLFVSFMRMMWYSMYISQGNYAVDTLEALYE
                     DMQKDKLVHGNVNNFKNYNIEFENVSFAYNDKAVIENLSFNLEEGKSYALVGSSGSGK
                     STVAKLISGFYNVNKGSIKIGGIAISEYSDEALIKAISFVFQDSKLFKKSIYDNVALA
                     NKDATKDDVMRALKLAGCDLILDKFPERENTIIGSKGVYLSGGEKQRIAIARAILKDS
                     KIIIMDEASASIDPDNEFELQKAFKNLMKDKTVIMIAHRLSTIKDLDEIIVMDSGKII
                     ERGSDKELMSKDTRYKSLQEMFNSANEWRVSNERVL"
     gene            1620..3341
                     /locus_tag="VXB91_001901"
     CDS             1620..3341
                     /locus_tag="VXB91_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019214631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0471302.1"
                     /translation="MKEFYKKRFALTDGGARNLSKATLASFFVYCINMLPAILLMIFA
                     QEVLENMGKSNGFYIVFSVLTLIAMYILLSIEYDKLYNTTYQESADLRIRTAENLSKL
                     PLSYFSKHDISDISQTIMADIEGIEHAMSHSIPKVGGMVLFFPLISVMMLAGNVKMGL
                     AVIIPSILSFIFIPLSKKYQVNGQNRYYDVLRKNSESFQENIEMQMEIKAYNLSKDIK
                     DDLYKKMEDSERVHLKAEVTTILTLSISSIFSFISLAVVIFVGVNLIINKEINSLYLI
                     GYLLAAMKIKDSLDASKEGLMEIFYLSPKIERLKEIQNQDLQEGDDYSLKKFDIDLKD
                     VEFAYNKDAKVLNGVSFKAKQGEVTALVGASGCGKTTILKLISRLYDYDKGQILIDGK
                     DIKEISTESLFDKVSIVFQDVVLFNQSIMENIRIGKQDASDEEVKRAAKLANCTDFIE
                     KMDKGFDTVIGENGAELSGGERQRLSIARAFLKDAPILILDEITASLDVNNEKKIQES
                     LNNLVKDKTVVIISHRMKSIENADKIVVLQNGRVESEGKHEELLQKSKIYKNLIEKTK
                     MAEEFIY"
     gene            3352..3936
                     /locus_tag="VXB91_001902"
     CDS             3352..3936
                     /locus_tag="VXB91_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEV0471303.1"
                     /translation="MDNKKLKVKDLVSIGVFGVIYFAFMFGVGMMGLIPILFLIYPTV
                     LAIVAGTVVMLFMAKVQKPWALFIFGMISPLVMFAAGHTYVVVVLSLIVMIIAELIRK
                     IGNYNSFKYNMLSYAIFSTWICSSLMQMLLAKEKYMEWSLMTMGKDYVDVLEKLITYP
                     HMALVALGAFLGGILGAYIGKALLKKHFEKAGIV"
     gene            3936..4631
                     /locus_tag="VXB91_001903"
     CDS             3936..4631
                     /locus_tag="VXB91_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEV0471304.1"
                     /translation="MSTFSSNAPFNPNPISKILVVFITGLTVMHSINIRFELAIVCLI
                     GILLYLNGYKKTLFKWIILCGILYSLPNFMVLSELNPIVKMFLSIPIVIRMFILPFMA
                     ASFMIKTSDVGAIISSMDKLKISKNVSIPIAVMFRFFPSFKEEKKNIKMAMRVRGISF
                     KNPVKYLEYVSMPLLIISSNISDDIAKAAETKAIENPIAKTRYIRVKIQLIDFVYVLA
                     VAGLIVGGLIWLK"
     gene            4619..>5319
                     /locus_tag="VXB91_001904"
     CDS             4619..>5319
                     /locus_tag="VXB91_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0471305.1"
                     /translation="MVEIKNLSLDYGEEHILDDISLSIAEGECVLFTGKSGNGKSSLI
                     NSINGLAVRYDNAKTKGEIIIDGKNIKNLELYQISMLVSTVFQNPKTYFFNVNTTLEL
                     LFYLENIGLAREEMDRRLKDMLKIFPIKNLLNRNIFNLSGGEKQILCIAASYIAGTKI
                     IVMDEPSSNLDIKSINVLAKMLKILKEKGISIIVAEHRIYYLMDIVDRVFLIDKGKLK
                     KTYTRSEFLKLDKNE"
BASE COUNT         1912 a          696 c         1000 g         1711 t
ORIGIN      
        1 caaatttcta gataagttaa taattaattc aaacttatcc ggtgcagaga gtatagcatt
       61 aaaatctgtt attacactaa caagtggagc gatattttat tttgtctcag gaatgttttc
      121 acatatcttg ggatttaggc ttgaaacaaa tttaagaaaa aggggaatcg atggtctgga
      181 aaaagcaagt tttaggttct ttgacttaaa tccatctggt caaataagaa agatcataga
      241 tgataatgca gcacaaactc atcaggtggt agcacacatg attcccgata gttctcaggc
      301 aataatcaca cccgtacttg tacttgcact tggctttata gtaagtataa gggttggcat
      361 aattttgctt gctcttacta taattggtgg cttaatttta ggggcaatga tgggcgagca
      421 agaatttatg aagatatacc aagaatccct atctaaacta agtgctgaaa ctgttgagta
      481 cgtgagagga atgcaagttg taaaaatatt taaagcaaat gtagagtctt ttaaaagctt
      541 ttataaggcg ataaaagatt actcaaagta tgcttatgat tattccctat cttgtaaaag
      601 gccttatgtt ttgtatcaat ggttattttt tggactgatt gcaattttaa ttattcctat
      661 agtttatttt atgactagct tagctagcgc aaaggtgatt ttacttgagc ttatcatgat
      721 tttattttta tcaggagttc tctttgtttc attcatgaga atgatgtggt actccatgta
      781 tatttctcaa ggaaattatg cagtagatac tttagaggcg ctttacgaag atatgcaaaa
      841 agacaaatta gtgcatggta atgtcaataa ttttaaaaac tataatatag aatttgagaa
      901 tgttagcttt gcttataatg ataaagctgt cattgaaaat ttatccttta atttagaaga
      961 aggaaagtcc tacgcacttg tcggttcatc tggatcaggc aaatcaacag tagcaaaact
     1021 tatatcaggt ttttacaatg ttaataaagg aagcataaag ataggcggga tagcaataag
     1081 tgaatattct gacgaagcct taattaaagc catttccttt gtttttcaag attcaaaatt
     1141 attcaagaag agcatttatg ataatgtagc tttagctaat aaagatgcga cgaaagatga
     1201 cgttatgaga gccttaaaat tagcaggatg cgatttaata ttagacaaat tcccagaaag
     1261 agaaaataca atcataggct caaaaggtgt ttatttatcc ggtggagaaa aacaaagaat
     1321 tgcaattgct agagcaattt taaaggattc caaaattatt attatggatg aagcatcagc
     1381 atctattgac ccagataacg agtttgaatt gcaaaaagct tttaaaaatc ttatgaagga
     1441 taaaacagtt atcatgattg cacacaggct atctacaatt aaagaccttg atgaaattat
     1501 tgtcatggat agtggaaaaa ttatagaaag agggtctgac aaagaattaa tgtcaaaaga
     1561 tacaaggtat aagagcctgc aagagatgtt taacagtgcg aatgaatgga gggtttcaaa
     1621 tgaaagagtt ttataaaaaa agatttgctc ttacagatgg aggagcaaga aatttaagta
     1681 aagcaacact ggcttcattt ttcgtttatt gtataaacat gcttcctgcc atattactta
     1741 tgatttttgc tcaggaagtt ttggaaaata tgggcaaaag caatggcttt tatatagtat
     1801 tctcagtttt gactttgata gcaatgtata ttttgctttc tatcgaatac gataaattat
     1861 ataacacaac ctatcaagaa agtgcagatt taagaataag gacagcggag aatttatcaa
     1921 aattacctct atcttacttt tctaaacatg acatttccga catttcacaa acaatcatgg
     1981 ctgatattga aggcatagag catgcaatga gccactcaat accaaaggtg ggcggcatgg
     2041 tactgttttt cccattaata tctgtaatga tgctagcggg caatgtcaag atgggtttag
     2101 ctgtaattat tccatctatt ttaagcttta tatttatacc tttatctaaa aaatatcagg
     2161 ttaatggaca gaatagatat tatgatgtct taagaaaaaa ctcagaaagc tttcaagaaa
     2221 atatcgaaat gcaaatggag attaaagcat ataatttatc gaaggatatt aaagatgact
     2281 tatataaaaa aatggaagat agtgagagag tacacttaaa ggcagaagta actacaattt
     2341 taactttgtc tatatcttca atatttagct ttatatctct tgctgttgtg atatttgtcg
     2401 gcgtaaatct aattattaat aaagagataa attctctcta ccttatagga tatttactag
     2461 ctgctatgaa gataaaagac tctttagatg catctaaaga gggcttgatg gaaatatttt
     2521 atttatcgcc caaaatagaa agattaaaag aaattcaaaa tcaagattta caagaaggcg
     2581 atgactatag cttaaaaaaa tttgatattg atctaaaaga tgttgagttt gcctacaata
     2641 aagacgcaaa agttttaaat ggtgtaagtt ttaaagctaa gcagggagag gtcactgctt
     2701 tggtaggtgc aagtggctgc ggtaaaacaa ctatcttgaa acttatatca agactttatg
     2761 attatgacaa gggacaaatc ttaatcgatg gcaaagatat aaaagaaata tcaacagaat
     2821 ctctttttga taaggtctct atagttttcc aagatgtggt tctctttaat caaagcatta
     2881 tggaaaatat tagaatcgga aagcaagatg caagtgacga agaggttaaa agagcagcaa
     2941 aacttgcaaa ttgcacagat tttatagaaa aaatggataa aggtttcgat acagttattg
     3001 gtgagaacgg agctgagcta tcaggaggag aaagacaaag attatcaata gccagagcct
     3061 tcttaaaaga tgcgccgata ttgatcttag atgagataac agcaagcctt gatgttaaca
     3121 acgagaaaaa gattcaagag tctttaaata atttagttaa agataaaact gttgtaatca
     3181 tttcacatag aatgaaatcc atagaaaatg cagacaagat agtagttctt caaaacggaa
     3241 gagtagaaag cgaaggtaag catgaagagc ttttacaaaa atcaaaaatt tacaaaaatt
     3301 taatagaaaa gacaaaaatg gcagaagaat ttatttatta ggaggactac aatggataat
     3361 aaaaaattaa aagtaaaaga tttagtaagt atcggtgttt ttggcgtaat ttattttgcc
     3421 ttcatgtttg gagttggtat gatgggcttg attccaatat tgttcttaat atacccgaca
     3481 gtattagcca tagttgcagg aactgttgtt atgttattta tggctaaggt tcaaaagcca
     3541 tgggcactat ttatatttgg tatgatatca ccacttgtga tgtttgcagc tggtcatacc
     3601 tacgtagttg tggttttatc acttatagta atgataatag cagaattaat tagaaagatt
     3661 ggtaattata attcatttaa atacaatatg ctttcttatg caatcttcag cacatggata
     3721 tgtagctctt taatgcaaat gcttttagca aaagaaaaat atatggagtg gtctttgatg
     3781 acgatgggaa aagattatgt tgatgtatta gaaaagttaa taacttatcc tcacatggct
     3841 ttagtagcct taggtgcttt cttaggagga attcttggag catatatagg caaggctcta
     3901 ttgaaaaaac actttgaaaa agcaggcatt gtataatgtc tactttttct tcaaatgctc
     3961 cctttaatcc caatccgatc tctaagatat tagtcgtatt tatcacaggc ttaactgtta
     4021 tgcatagcat aaacatccgt tttgagctgg caattgtttg tcttattggt attttgcttt
     4081 atttgaatgg atacaaaaaa acacttttca aatggattat attgtgtggg atactttact
     4141 ccttgcctaa ttttatggtg ttatctgaat taaaccctat agttaagatg tttttgagta
     4201 tacctattgt tattagaatg tttattttac catttatggc agcaagcttt atgataaaga
     4261 cctcggatgt aggcgcaata atttcatcga tggataagct taagatttca aagaatgtat
     4321 ccatacctat tgcggttatg tttagattct tcccatcttt taaggaggag aagaaaaaca
     4381 tcaaaatggc tatgagagta agagggataa gttttaaaaa cccagtcaaa tatcttgaat
     4441 atgtttctat gccactactc attatatcat ctaatatatc agatgacatt gcaaaagcgg
     4501 cagaaacaaa ggcaatagaa aatccaattg ccaagaccag atacattcgc gtaaagatac
     4561 agctaattga ttttgtttat gttttagcgg ttgctggact tattgtggga ggcttaatat
     4621 ggttgaaata aaaaatttaa gtcttgatta tggtgaagag catatattag atgatatatc
     4681 actatccata gccgagggag agtgcgtgct atttacagga aaaagtggaa atggtaagtc
     4741 atctttaata aattcaatca atggactagc tgtaaggtat gataacgcaa agacaaaggg
     4801 cgaaataatt attgatggta agaatataaa aaatttggaa ctttatcaaa tctcaatgct
     4861 tgtttcaact gtttttcaaa atcctaagac atattttttt aatgtcaata cgacattaga
     4921 attattattt tatttggaaa atatcggtct tgcaagagaa gagatggaca ggcgtttgaa
     4981 ggatatgctt aagatattcc cgataaaaaa tcttttgaac agaaatatat ttaatctatc
     5041 cggcggtgaa aaacaaattc tttgcattgc agcttcttat atagcaggta caaagattat
     5101 agttatggat gagccttcat cgaatttaga tattaaaagc ataaatgttt tggcaaagat
     5161 gctaaagata ttaaaagaga aaggcataag cataattgtt gcagagcata gaatttatta
     5221 tttgatggac atagttgacc gtgtattttt aatagataaa ggaaagctta aaaaaactta
     5281 tactagaagt gaatttttaa agctagataa aaatgaatt
//
LOCUS       DAVLBE010000083         5226 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.083, whole genome shotgun sequence.
ACCESSION   DAVLBE010000083 DAVLBE010000000
VERSION     DAVLBE010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5226)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5226)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5226
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.083"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(374..1102)
                     /locus_tag="VXB91_001905"
     CDS             complement(374..1102)
                     /locus_tag="VXB91_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV0471306.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            1260..2669
                     /locus_tag="VXB91_001906"
     CDS             1260..2669
                     /locus_tag="VXB91_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEV0471307.1"
                     /translation="MKKKLVFPNLFWWGAASSGPQTEGQYGKVHENVMDYWFKTHPED
                     FFDNVGPLVASNFFHTYTEDFHLMKEIGVNSFRTSIQWSRLIKNLETGEPDPKGIAFY
                     NAIIEEAKKNQMDLVMNLHHFDLPVELLQKYGGWESKHVVELFVKFAKTAFTCFGDKV
                     HYWTTFNEPMVIPEAGYLYAFHYPNLKGKGKEAVQVIYNLNLASAKVIQLYRSLELDG
                     KIGIILNLTPAYPRSNSPEDLEASRFTDDFFNKVFLNPAVKGTFPERLVKQLERDGVL
                     WSHTEKELQLMKSNTVDFLGVNYYHPKRVQAQANPEEYQTPWMPDQYFKEYEWPERRM
                     NPYRGWEIFPKSIYDIAMIVKEEYGNIPWFISENGMGVENEARFIDENGVIDDVYRIE
                     FYEEHLRWLHKAIEEGSHCFGYHAWTAFDCWSWNNAYKNRYGFISVDLETQKRTIKSS
                     GRWYRKVSDNNGFEVEIEE"
     gene            2687..3982
                     /locus_tag="VXB91_001907"
     CDS             2687..3982
                     /locus_tag="VXB91_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV0471308.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTRFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPLAA
                     SMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVNRSFSVLLPVMTVISLFGVVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            3987..4295
                     /locus_tag="VXB91_001908"
     CDS             3987..4295
                     /locus_tag="VXB91_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0471309.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNIPVDTIDMRDYGMMNGAKVLEQALAWIGEIR
                     "
     gene            4292..4600
                     /locus_tag="VXB91_001909"
     CDS             4292..4600
                     /locus_tag="VXB91_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV0471310.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEAHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
BASE COUNT         1763 a          879 c          947 g         1637 t
ORIGIN      
        1 ttgaacaaat aaattgggag attgaaattc atttctagca atttgttaga agtcacagtc
       61 tactattcta acctcagtat actatatgtg ttacaagaaa agactcaaaa acttctcgtc
      121 agtgtaagaa tatttgaaac actatttaaa actaaataac tataagaagt agatcaggtg
      181 aacaatttca gtacctactc tataagctat acgaagatat ttttcaacat gatggataaa
      241 acgatcactc ttttaaagcc atcttattta gaaaagagaa accatttaag catagatggg
      301 accttcttgc cctgttttaa atttttctta aactagagtc tgtaaaagat tggcttcatt
      361 ttcacatttt ctcctaggag gaatgtcgta atgcaaaaga attaaattca aataaatcat
      421 agcgatgacg actaatcgag tactcaaacg gagttccgtt atccaaataa gccacttgtt
      481 ctacttcaaa taccggttcc gttggaagga gctgcaagta atgttgctca ttttctgaac
      541 tagaagaagc tcgtaagatt tttgtagcac tggcaatatg caatcctaac tttccttcaa
      601 tgtaattgta aatcgatttt tgtaaaatat cttcagtaat acctggaata acatcggtac
      661 tcatataagt ttgttccaga acataaggtt taccgtcaat aatacgcagg cggtaaatat
      721 tataaactgg actctgcaaa gcgacctgta gtttttctgc taaaaattca tttgcaaatt
      781 ctaatttgaa gtgaataatc ctcgagtcaa ttgtagaatg agcatcttca gatatttttg
      841 tcagtccccg gatatctctt tctggaacga ttaattttct ttttgagctg ccacgagaga
      901 gaacaaaggt tccctgccca cgttttctaa aaattaagcc ctcagaaact aacaagtcta
      961 aagctttttt gatcgtcatt cgactacagg caaactgttt agctaatgtc atttcatcag
     1021 gtaattgttc gttcatggta tatttattac aaagaatctt ttcacgaatc tcattgtaaa
     1081 taaataaata ttttgtactc atttaatctg gttctctcta taatattcta atagtagtat
     1141 aacaaagttc aagaaatgag gcaaacacaa gatatgtatc aacaattttt aaaaatgtct
     1201 agacaaattt taaaattatg ctatacttta tgtatagaat aatagaaagg aggttgagca
     1261 tgaaaaaaaa gttagtattt cctaatctgt tttggtgggg agcagcttct agcggacctc
     1321 agacagaagg tcaatatgga aaagtacatg aaaatgtgat ggactactgg ttcaaaacgc
     1381 atccagaaga ttttttcgat aatgtcggac ctcttgtagc cagtaacttt tttcatactt
     1441 acaccgaaga tttccacttg atgaaggaaa ttggagttaa ttctttccgc acttccatcc
     1501 aatggagtcg actcatcaag aatttagaga caggtgagcc tgatccaaaa ggtattgctt
     1561 tctacaatgc catcattgaa gaagctaaaa agaaccagat ggatcttgtg atgaatttac
     1621 atcattttga tttaccagtg gaacttcttc aaaaatacgg tggttgggaa agcaaacatg
     1681 tagtggagtt attcgtgaag tttgccaaga ctgctttcac atgctttgga gataaggttc
     1741 attactggac aactttcaat gagccaatgg tcattccaga agcaggatac ttatatgctt
     1801 tccattatcc aaatctaaaa ggaaagggaa aagaggccgt acaagtcatc tataatctaa
     1861 accttgctag tgcaaaagtg attcaactat atcgctcatt agaacttgat ggaaagattg
     1921 ggattatttt aaacttgaca cctgcttatc caagaagtaa ttctccagaa gacttagaag
     1981 caagtcgatt tacagatgac ttctttaaca aagtcttctt gaatccagct gttaaaggaa
     2041 ctttcccaga aagattggta aaacagctag agagagatgg cgtgttatgg agtcataccg
     2101 aaaaagagct tcaactgatg aaatcaaata cggttgattt tcttggagta aactactacc
     2161 atccaaaacg tgttcaagca caagcaaatc ctgaggaata tcagacgccc tggatgccag
     2221 accaatactt caaagagtat gaatggccgg agcgtcgcat gaatccatat cgtggttggg
     2281 aaatttttcc gaaatccatt tatgatattg ctatgattgt gaaggaagaa tatggtaata
     2341 tcccatggtt tatcagtgaa aacggaatgg gtgttgaaaa cgaagcacgg tttatcgatg
     2401 aaaatggagt tatcgatgac gtgtatcgta ttgaatttta tgaagaacat ttaagatggc
     2461 tacataaagc cattgaagag ggaagtcact gttttggata ccacgcttgg accgcatttg
     2521 attgctggtc ttggaataat gcatataaga atcgttacgg atttatctcc gttgatttag
     2581 aaacgcaaaa gagaaccatc aagagctcag gaagatggta tcgcaaagta agtgacaata
     2641 acggttttga agtagaaatt gaggagtaaa gagaggagat attcatatga aaaactcaaa
     2701 atttatagac caatttgcca cctttgctgg taaactaggg aaccaaattc atttaaaaac
     2761 cctaagagat gcattcgtaa cagtaatgcc attatatatt ttggcaggtt taatcgttct
     2821 tttgaacaac acggtattta agtggatttt ccaaggggat acattaacaa gattccaata
     2881 ttggggaata acaattgcaa acggtacttt aagtatttca ggtatgatta ttgctgtaat
     2941 ggttggttat ttcttagcta aaaacagaga tttcgaaaac ccgttagcag catcaatgct
     3001 atcattagtt tctttaattg tgatgatgcc aaatacagtt tctgtagttc ctgacggagc
     3061 aaaagatgct gtaaacattt caggtgttct ttcattcaac aacacaggta caggcgcaat
     3121 gttcgccggg gttatcgtag cgattattgc aacagaatta ttcattgaat tatcaaatgt
     3181 taaagcttta caaatgaacc ttggtgaaaa tattccacca gctgttaata gatcatttag
     3241 cgtattactt ccagtcatga ccgtcatctc cttatttggg gttgtttcag cattattatt
     3301 caatataact ggaatgaact taatctcaat cattacaatc tttattcaag aaccaattcg
     3361 tcatattggt acaagcttaa tcggggtcat tattatttac tctttaggaa atatgttatg
     3421 gctatttggt attcaccaag cagttattta cagtgccatc ctagaaccat tactattaat
     3481 taacattact gaaaacatca ctgcagcaaa taatggacaa gccattccac acatcatcaa
     3541 cctatcacaa atacaaacat tcgctttaat gggtggtagt ggatctacat tatgtttatt
     3601 aatagcaaca ttcttagtga gtcgcaatgc tgtctctaaa aacgtggcta aattatcttt
     3661 tggacctggt atcttcaata tcaatgaacc agtattattc ggttacccaa tcgtttataa
     3721 catttcatta gctattccat ttatcacagt tccagtcctt ggtattttaa tcagctactt
     3781 agcaacagtt acaggattca tgagtcctgc atttatacaa gttccttgga ctacaccagt
     3841 attcttaaat gcatggttag caacagcagg ggacgtgaga gcagttctag ttcaattcat
     3901 catctttgca cttggagttc ttctatacat tccatttatc aaagttaatg acaaagttgt
     3961 tgaacaagaa atggaaggtt aagattatga aacaaatttt attagtatgt aatgcgggaa
     4021 tgtcgacaag tatgcttgtt aaaaaaatgc aacaaagtgc gactgaacgt gggattgaaa
     4081 tctctatcca agcaaaatca atgacagaag ctaaaaagaa tatccatgaa gcagatgtca
     4141 ttctaattgg gccacaaatt cgttatgagt tacttgctgt gaaagaaatt gcaggaaata
     4201 tccctgtaga taccattgat atgcgggatt acggaatgat gaatggagca aaagttctgg
     4261 aacaagcact tgcatggata ggagaaataa gatgacagaa gaaatggaat atatctgttt
     4321 tcagctcatt gccaatagtg gagcagccaa atcatccttt attgaagcca tccaactagc
     4381 taaggcagga aatttaaaag aagcgaaaat taaagttgaa gaagcggaag actccttagt
     4441 agaagcgcac aagattcact ctaatctcat acaaaaagaa gctactggag aaaaaatagg
     4501 attctccttg ctatttatgc atgcagaaga ccaaatggct tcaacagaga ttattcagtt
     4561 gctatctaaa gaattcatcg atctctatca aaataaatag gaacactgtc attcccatct
     4621 gtctttatta atgacgacta cattgtagga acctccaaaa gttggacaaa atgattgaaa
     4681 ggattggatc ctgcattaca caagatccaa tccttttctt ttactctagt ttttataata
     4741 tgttgaatct agaatagtcc actgtagttt ctaaaaaatt gctggaaatg gatgttaagc
     4801 tccaatttat ttgtttatat cttatttcag tttactatac tagcttatta ttctagtgaa
     4861 aaattgaatg agccactatt tatttaatat gtatgatgag ggaatgactc aaaaacttct
     4921 tgtcgatata agaatatctg agatagtatt ttaaaacgaa aggactataa aagctcattt
     4981 ccttcgcact tattttatag agatctatca ttatactctt tagaaatcaa aaagcaacac
     5041 accttgtcat cgttttatcg taaatctgtt aatgaggggg ctagtcttat ctgcaatctc
     5101 aaatcagtgt tttgagctga atggcactcg ttttctagtt tgctctttga ttttaattgg
     5161 gccttagtaa atactactct taaattaaac tatagtgaat tgaaataaga tgtgaacaac
     5221 tctatc
//
LOCUS       DAVLBE010000084         5055 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.084, whole genome shotgun sequence.
ACCESSION   DAVLBE010000084 DAVLBE010000000
VERSION     DAVLBE010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5055)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5055)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5055
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.084"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            185..1730
                     /locus_tag="VXB91_001910"
     rRNA            185..1730
                     /locus_tag="VXB91_001910"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            1782..1854
                     /locus_tag="VXB91_001911"
     tRNA            1782..1854
                     /locus_tag="VXB91_001911"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1815..1817,aa:Ala,seq:tgc)
     gene            1979..4880
                     /locus_tag="VXB91_001912"
     rRNA            1979..4880
                     /locus_tag="VXB91_001912"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            4957..>5055
                     /gene="rrf"
                     /locus_tag="VXB91_001913"
     rRNA            4957..>5055
                     /gene="rrf"
                     /locus_tag="VXB91_001913"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         1425 a         1025 c         1487 g         1118 t
ORIGIN      
        1 gttgacaagt gaaagtggct gtgatatact aatatagttg tcgcttgaga gaagcaagtg
       61 acaaagacct ttgaaaactg aacaagacga accaatgtgc agggcgctac aacataagtt
      121 gtagtactga acaatgaaaa aacaataaat ctgtcagtga cagaaatgag taagaactca
      181 aacttttaat gagagtttga tcctggctca ggacgaacgc tggcggcgtg cctaatacat
      241 gcaagtagaa cgctgaagga ggagcttgct tctctggatg agttgcgaac gggtgagtaa
      301 cgcgtaggta acctgcctgg tagcggggga taactattgg aaacgatagc taataccgca
      361 taagagtaga tgttgcatga catttgctta aaaggtgcac ttgcatcact accagatgga
      421 cctgcgttgt attagctagt tggtggggta agggctcacc aaggcgacga tacatagccg
      481 acctgagagg gtgatcggcc acactgggac tgagacacgg cccagactcc tacgggaggc
      541 agcagtaggg aatcttcggc aatggacgga agtctgaccg agcaacgccg cgtgagtgaa
      601 gaaggttttc ggatcgtaaa gctctgttgt aagagaagaa cgagtgtgag agtggaaagt
      661 tcacactgtg acggtatctt accagaaagg gacggctaac tacgtgccag cagccgcggt
      721 aatacgtagg tcccgagcgt tgtccggatt tattgggcgt aaagcgagcg caggcggtta
      781 gataagtctg aagttaaagg ctgtggctta accatagtag gctttggaaa ctgtttaact
      841 tgagtgcaag aggggagagt ggaattccat gtgtagcggt gaaatgcgta gatatatgga
      901 ggaacaccgg tggcgaaagc ggctctctgg cttgtaactg acgctgaggc tcgaaagcgt
      961 ggggagcaaa caggattaga taccctggta gtccacgctg taaacgatga gtgctaggtg
     1021 ttagaccctt tccggggttt agtgccgtag ctaacgcatt aagcactccg cctggggagt
     1081 acgaccgcaa ggttgaaact caaaggaatt gacgggggcc cgcacaagcg gtggagcatg
     1141 tggtttaatt cgaagcaacg cgaagaacct taccaggtct tgacatccct ctgaccgctc
     1201 tagagataga gttttccttc gggacagagg tgacaggtgg tgcatggttg tcgtcagctc
     1261 gtgtcgtgag atgttgggtt aagtcccgca acgagcgcaa cccctattgt tagttgccat
     1321 cattcagttg ggcactctag cgagactgcc ggtaataaac cggaggaagg tggggatgac
     1381 gtcaaatcat catgcccctt atgacctggg ctacacacgt gctacaatgg ctggtacaac
     1441 gagtcgcaag ccggtgacgg caagctaatc tcttaaagcc agtctcagtt cggattgtag
     1501 gctgcaactc gcctacatga agtcggaatc gctagtaatc gcggatcagc acgccgcggt
     1561 gaatacgttc ccgggccttg tacacaccgc ccgtcacacc acgagagttt gtaacacccg
     1621 aagtcggtga ggtaaccgta aggagccagc cgcctaaggt gggatagatg attggggtga
     1681 agtcgtaaca aggtagccgt atcggaaggt gcggctggat cacctccttt ctaaggataa
     1741 ggaactgcgc attggtcttg tttagtcttg agaggtcttg tggggcctta gctcagctgg
     1801 gagagcgcct gctttgcacg caggaggtca gcggttcgat cccgctaggc tccattggtg
     1861 agagatcacc aagtaatgca cattgaaaat tgaatatcta tatcaaatag taacaagaaa
     1921 ataaaccgaa aacgctgtag tattaataag agtttatgac tgaaaggtca gaaaataagg
     1981 ttaagttaat aagggcgcac ggtggatgcc ttggcactag gagccgacga aggacgtgac
     2041 aaacgacgat atgccttggg tagctgtaag taagcgatga tccagggatt tccgaatggg
     2101 ggaacccaac aggtaatacc tgttacctac atctgttaag gatgtgagga ggaagacgca
     2161 gtgaactgaa acatctaagt agctgcagga agagaaagca aaagcgattg ccttagtagc
     2221 ggcgagcgaa acggcagaag ggcaaaccga agagtttact cttcggggtt gtaggactgc
     2281 aatgtggact caaagattat agaagaatga tttgggaaga tcagccaaag agagtaatag
     2341 cctcgtattt aaaatagtct ttgtacttag cagtatcctg agtacggcgg gacacgtgaa
     2401 atcccgtcgg aatctgggag gaccatctcc caaccctaaa tactccctag tgaccgatag
     2461 tgaaccagta ccgtgaggga aaggtgaaaa gcaccccggg aggggagtga aatagaacct
     2521 gaaaccgtgt gcctacaaca agttcgagcc cgttaatggg tgagagcgtg ccttttgtag
     2581 aatgaaccgg cgagttacgt tatgatgcga ggttaagttg aagagacgga gccgtaggga
     2641 aaccgagtct gaatagggcg ccttagtatc atgacgtaga cccgaaacca tgtgacctac
     2701 ccatgagcag gttgaaggtg cggtaagacg cactggagga ccgaaccagg gcacgttgaa
     2761 aagtgcttgg atgacttgtg ggtagcggag aaattccaaa cgaacttgga gatagctggt
     2821 tctctccgaa atagctttag ggctagcgtc gacattagag attcttggag gtagagcact
     2881 gtttgggtga ggggtccatc ccggattacc aatctcagat aaactccgaa tgccaatgaa
     2941 ttatggtcgg cagtcagact gcgagtgcta agatccgtag tcgaaaggga aacagcccag
     3001 accaccagct aaggtcccaa aataattgtt aagtggaaaa ggatgtgggg ttgcacagac
     3061 aactaggatg ttagcttaga agcagctatt cattcaaaga gtgcgtaata gctcactagt
     3121 cgagtgaccc tgcgccgaaa atgtaccggg gctaaaacaa tttaccgaag ctgtggatac
     3181 ctttataggt atggtaggag agcgttctat gtgtgatgaa ggtataccgt gaggagtgct
     3241 ggaacgcata gaagtgagaa tgccggtatg agtagcgaaa gacaggtgag aatcctgtcc
     3301 accgtaagac taaggtttcc aggggaaggc tcgtccgccc tgggttagtc gggacctaag
     3361 gagagaccga aaggtgtatc cgatggacaa caggttgata ttcctgtact agagtatgta
     3421 gtgatggagg gacgcagtag gctaactaaa gcagacgatt ggaagagtct gtctaagcag
     3481 tgaggtgtga attgagtcaa atgcttaatt ctataacatt gagctgtgat ggggagcgaa
     3541 gtttagtagc gaagttagtg acgtcacact gccaagaaaa gcttctagcg tttaaacata
     3601 ctctacccgt accgcaaacc gacacaggta gtcgaggcga gtagcctcag gtgagcgaga
     3661 gaactctcgt taaggaactc ggcaaaatga ccccgtaact tcgggagaag gggtgctgac
     3721 ttaaagtcag ccgcagtgaa taggcccaag caactgttta tcaaaaacac agctctctgc
     3781 taaatcgtaa gatgatgtat agggggtgac gcctgcccgg tgctggaagg ttaagaggag
     3841 tgcttagcgt aagcgaaggt atgaattgaa gccccagtaa acggcggccg taactataac
     3901 ggtcctaagg tagcgaaatt ccttgtcggg taagttccga cccgcacgaa aggcgtaatg
     3961 atttgggcac tgtctcaacg agagactcgg tgaaatttta gtacctgtga agatgcaggt
     4021 tacccgcgac aggacggaaa gaccccatgg agctttactg cagtttgata ttgagtgtct
     4081 gtaccacatg tacaggatag gtaggagtct aagagatcgg gacgccagtt tcgaaggaga
     4141 cgctgttggg atactaccct tgtgttatgg ccactctaac ccagataggt gatccctatc
     4201 ggagacagtg tctgacgggc agtttgactg gggcggtcgc ctcctaaaag gtaacggagg
     4261 cgcccaaagg ttccctcaga atggttggaa atcattcgca gagtgtaaag gtataaggga
     4321 gcttgactgc gagagctaca actcgagcag ggacgaaagt cgggcttagt gatccggtgg
     4381 ttccgtatgg aagggccatc gctcaacgga taaaagctac cctggggata acaggcttat
     4441 ctcccccaag agttcacatc gacggggagg tttggcacct cgatgtcggc tcgtcgcatc
     4501 ctggggctgt agtcggtccc aagggttggg ctgttcgccc attaaagcgg cacgcgagct
     4561 gggttcagaa cgtcgtgaga cagttcggtc cctatccgtc gcgggcgtag gaaatttgag
     4621 aggatctgct cctagtacga gaggaccaga gtggacttac cgctggtgta ccagttgtct
     4681 tgccaaaggc atcgctgggt agctatgtag ggaagggata aacgctgaaa gcatctaagt
     4741 gtgaaaccca cctcaagatg agatttccca tgattatata tcagtaagag ccctgagaga
     4801 tgatcaggta gataggttag aagtggaagt gtggcgacac atgtagcgga ctaatactaa
     4861 tagctcgagg acttatccaa agtaactgag aatatgaaag cgaacggttt tcttaagttg
     4921 aatagatatt caattttgag taggtattac tcagagttaa gtgacgatag cctaggagat
     4981 acacctgtac ccatgccgaa cacagaagtt aagccctaga acgccggaag tagttggggg
     5041 ttgccccctg tgaga
//
LOCUS       DAVLBE010000085         4896 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.085, whole genome shotgun sequence.
ACCESSION   DAVLBE010000085 DAVLBE010000000
VERSION     DAVLBE010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4896)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4896)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4896
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.085"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            120..701
                     /locus_tag="VXB91_001914"
                     /pseudo
     CDS             120..701
                     /locus_tag="VXB91_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018164186.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
     gene            858..1226
                     /locus_tag="VXB91_001915"
     CDS             858..1226
                     /locus_tag="VXB91_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV0471311.1"
                     /translation="MAVGLSYEDPAVKLLNDGANIKVVYPKEGTVFLPASAAIVKKAK
                     NMENDKKFIDFIISQEVQDTLGTTTTNRPVRKNAKTSENMKPIDKIKTLTEDYDYVIK
                     NKSDIVKKYNEVFTDIQSKQ"
     gene            1301..2329
                     /locus_tag="VXB91_001916"
     CDS             1301..2329
                     /locus_tag="VXB91_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0471312.1"
                     /translation="MNITIPKGSLFTLLGPSGCGKTTLLRMIAGFNSIKDGEFYFDDT
                     KINNMEPSKRNIGMVFQNYAIFPHLTVRDNVAFGLKQKKVPKEELIQQTNKYLELMQI
                     AQYADRKPDKLSGGQQQRVTLACALAVNPSVLLMDEPLSNLEAKLRLDMRQAIREIQH
                     EVGITTVYVTHDQEEAMAISDQIAVMKDGVIQQIGRPKELYHKPANEFVATFIGRTNI
                     IPANLEKRSDGAYIVFSDGYALRMPALDQVEEQAIHVSIRPEEFIKDESGDIEGTISD
                     SVYLGLNTEYFIETGFASKIQVSEESTFEEDLQKDNRIRLRINTQKLNIFSADGSQNL
                     IKGVNHGM"
     gene            2319..3955
                     /locus_tag="VXB91_001917"
                     /pseudo
     CDS             2319..3955
                     /locus_tag="VXB91_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
     gene            complement(4058..4750)
                     /locus_tag="VXB91_001918"
     CDS             complement(4058..4750)
                     /locus_tag="VXB91_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEV0471313.1"
                     /translation="MVKVRLYLIRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEMIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGREKMEEGSI"
BASE COUNT         1538 a         1041 c          848 g         1469 t
ORIGIN      
        1 gtgtactgtt atagattcaa tacactatag aatagaattg taggttttaa aaacgcttac
       61 attgttttaa aataaactta aataacacaa cggagatatc catcatgaaa aagaaataga
      121 tgtattatgc tgcttgttct tctaatgaat ctgccgatga cagttcatct gataaaggag
      181 acggtggttc gctagtcgtt tattcaccaa actcagaagg cttaattgga gcaactattc
      241 ctgcctttga agaaaaatat ggtatcaaaa tagaactgat tcaagctggt actggagaac
      301 ttttcaaaaa actagagtca gaaaaagaag ttcctgtagc tgatgttatc tttggtggtt
      361 cttatacaca atatgctacc cacggagaac tctttgaaaa ctatatttca aaagaaaatg
      421 ataatgttat caaagaatat caaaacacaa ctggcttctc tactccttat acactagatg
      481 gtagtgtttt aatcgtcaac cctgatttaa ctaaaggcat gaacatcgaa ggatatagcg
      541 accttctcaa acctgaacta aaaggaaaaa tcgcaactgc tgacccagca aactcttcta
      601 gcgcctttgc tcaattaaca aatatgctac aagctcaagg tggttacaaa gatgataagg
      661 cttggtctta tgtaaaagat cttttcacac ttattgatgg catagtgaaa tgaaataaga
      721 acaggacaaa ttaatcagga cagtcaaatc gatttctaac aatgttttag aagtagaggt
      781 gtactattct agtttcaata cactataaaa tcggttcaag ttcatctggt gtctataaag
      841 cagtcgttga tggagaaatg gctgttggtc tctcttatga ggatccagca gttaaactct
      901 taaatgacgg agctaacatt aaagtagtct atccaaaaga aggaaccgtc ttcctacctg
      961 ctagtgctgc tatcgttaaa aaagctaaaa atatggaaaa tgacaagaaa tttatcgatt
     1021 ttattatctc tcaagaagta caagatacac ttggtacaac cactactaac cgtcctgttc
     1081 gtaaaaatgc taaaacaagc gaaaacatga aaccaattga caaaatcaaa acactcactg
     1141 aagattatga ttatgtcatc aagaataaat cagatatcgt taagaaatac aacgaagtct
     1201 ttacagatat ccaatctaaa cagtaaaaaa ggttcactat gagtgagatc aaaattatta
     1261 acgccaaaaa atctaccacg atgtccctgt tattgagaat ttgaacatta caattccaaa
     1321 aggaagtctc tttacccttc ttggaccttc aggatgtggg aaaacgaccc ttcttcgtat
     1381 gattgcaggt ttcaacagta tcaaagatgg agaattttac ttcgatgata caaaaatcaa
     1441 taatatggaa cccagcaaac gcaatatcgg gatggttttc caaaactacg ctattttccc
     1501 acatttgact gtccgagaca acgttgcttt tggtcttaag caaaagaagg ttccaaaaga
     1561 agaattgatt caacagacca acaagtatct tgaactcatg caaattgctc aatatgcgga
     1621 tcgaaagccc gataaactca gtggtggaca acaacaacgt gtcaccttgg catgcgcctt
     1681 agcggttaat ccaagtgttc tcctcatgga cgagccactt agtaatctgg aggccaaact
     1741 tcgcttggat atgcgtcaag ccatccgaga aatccaacac gaagtgggaa ttacaactgt
     1801 ttatgtaacc cacgaccaag aagaagccat ggctatttca gatcaaattg ctgttatgaa
     1861 agatggggtg atccaacaaa tcggccgacc aaaagaactc tatcataaac cagctaatga
     1921 gtttgtggca acctttatcg gacgcacaaa tattatccct gccaatcttg aaaaacggag
     1981 cgacggcgct tatatcgtct tttcagatgg ctatgccctt cgaatgccag ctcttgatca
     2041 ggttgaggag caagctattc atgtaagcat tcgtcccgaa gagtttatca aagatgaatc
     2101 tggagatatt gaaggaacta ttagcgatag cgtctatctt ggactaaata cggagtattt
     2161 cattgagaca ggttttgcct caaaaattca agttagtgaa gaatcaactt ttgaagaaga
     2221 tctacaaaaa gacaatcgta ttcgtctacg aatcaatacg caaaaattaa acatcttttc
     2281 tgcagatggt tcccaaaacc tgataaaagg agtcaaccat ggaatgtaaa aaactaaata
     2341 tttggacagc ctcctctttc ttcatctttc ttacctatct tgtctttctc gtttatccta
     2401 tcattaccgt gctcaagtaa gcacttatac atgaaggata attctcacta gctaattttg
     2461 tcactttctt tagtaaagtc tactactctg agacactagt caacagtttc aaggtttcca
     2521 ttaccgctac tgtcacttcc ttagttgtag gaaccctatt agcttatctc ttctctatgt
     2581 atgacttcaa gggggagaaa tttctacaaa tattgattat cattgcttcc atgtcagctc
     2641 ctttcgtagg agcctactcc tgggttctct tgctaggacg aaatggggtc atcactaaat
     2701 ttttgacaaa tgcccttcat cttccagcta tcgatattta tggattcaaa ggaattgtac
     2761 ttgtctttac actgcaacta ttcccactgg tatttctata tgttgctgga acaatgaaca
     2821 gtattgacaa ttctctactt gaagcagctg aaagcatggg ggtccttcgg atttaagcgt
     2881 atcgtaacgg ttgttttacc tctcctagtt ccaaccttac tagcagctcc ttgcttgtat
     2941 ttatgagagc attctcagac tttggaacgc ctatgttgat tggcgaagga tatcggactt
     3001 tccctgtcct gatttatacc caatttatta gcgaggttgg aggaaattct gcttttgcaa
     3061 ttatggcgat tatcattgcc ttggcaattt tccttatcca aaaacacatt gcaaaccgct
     3121 acagtttcag catgaatctg ctccatccaa ttgagcctaa aaaaactaca aaaggaaaaa
     3181 tagctgccat ttatgcaaca gtctacggaa ttatctttat ctctgtttta cctcaaatct
     3241 acttaattta tacctctttc ctaaaaacat caggtatggt atctgttaaa ggttattctc
     3301 caaacagtta caaggtagct ttccatcgta tgggatctgc tattttcaat accattcgta
     3361 tccctttgat tgccttagtt ctagttgttc tatttgcgac atttatctcc tacctagccg
     3421 ttagaaaacg gaatttgttt acaaacttaa ttgacagcct cagtatggta ccttatattg
     3481 taccaggaac cgttctaggg attgccttca tttctctggt ctatttggaa gtggatttct
     3541 tatgattaca gggactgctt tcatcttgat tatgtctcta tctgccagaa aattacctta
     3601 tactattcgc tcatctgttg ctagcttaca acaaatagca ccaagtattg aagaagctgc
     3661 tgaaagctta ggaagtagtc gtctcaatat ctttgctaag attacaactc caatgatgct
     3721 atcggatatt atttctggag ccatcctatc ttgggtcaca ctgatttcag aactctctac
     3781 ttctatcctc ctctacaatg tcaaaacaag aacaatgact gtagctattt atacagaggt
     3841 tctcagagga aattacggtg tagccgcagc cttgtcaact atcctgactg ttctaacagt
     3901 aggttccttg ctcttgttta tgaaaatctc taaaagcaat agcattacac tttagttttc
     3961 cacatcaaaa acagccgaaa ggagtaccct cggctgtttt ttcttatctt gatattctta
     4021 tcaaatccct agctcatggc aagcaagtct agactgatta aatagagcct tcttccatct
     4081 tctcacgtcc tagctctcgg taactacggt caccgacaac ttcaacccta aactgaccgt
     4141 cctcatattc aagaatcgtc acgctaccat tatctagacc atgcggatgc atgccattaa
     4201 tcagataaac aatggttcca atagtcattc catggctgac aacaagggcg ttacctccac
     4261 cttgatcttc catttctttt gcaatcattt caaagccttc cttgattcgg ccactgagtt
     4321 tttcccagcc ttcagcccaa ccagctgtat cgacctctac caagccctca gccagttcag
     4381 cataagacaa ttggtgaacg tggtccacat taaagatacg aggaataatg cccatgaaaa
     4441 gatcgccatc ataggctcca tcaaaactac cgaaacacca ttctctgata cgcttgtcca
     4501 tgcgataagg gattttcccc tgcaagccaa gttcttcaag gataattccc atggtctgaa
     4561 tggtacgacc agaatcactc gaataagcgc gctcaaactg tagatcagat tctcgcaaac
     4621 caattcctaa ctcttgaatc cctcgttcac cttcagcagt taagggagta tcgctccaac
     4681 cttgcgcgcg accaatcgtg ttaaacatgg tcttgccatg acgtatcaaa tacaatcgta
     4741 cttttaccat tttccgtcct ccgtttgctt ctattatatc atgaatgata aaataaaagc
     4801 cacccataca ggcgactttt gaaggagatt attatgaaaa agtttaggag ttcattaaat
     4861 aaagatatta gatgaaaatc aaattcaaac taattc
//
LOCUS       DAVLBE010000086         4713 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.086, whole genome shotgun sequence.
ACCESSION   DAVLBE010000086 DAVLBE010000000
VERSION     DAVLBE010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4713)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4713)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4713
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.086"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            <1..321
                     /locus_tag="VXB91_001919"
     CDS             <1..321
                     /locus_tag="VXB91_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HEV0471314.1"
                     /translation="IYIVENQEIFVWFNKINPSLDSIFSTYELKMQDATISSSELEFL
                     CDLLLYKTLDQGRYNVDGPLVLARYLLGCEFEVKNLRMIISALQNTIPFESIKERIRP
                     HYGS"
     gene            311..631
                     /locus_tag="VXB91_001920"
     CDS             311..631
                     /locus_tag="VXB91_001920"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HEV0471315.1"
                     /translation="MEANKYKIGIIGSHDIILPFSMIGFDIFSAYQEQEAINTLRKLA
                     QSDYGVIYITEDIASMILDTIRHYDSQVVPAIILLPTHKQGLNLGLKRIEDNVEKAVG
                     HNIL"
     gene            694..2469
                     /locus_tag="VXB91_001921"
     CDS             694..2469
                     /locus_tag="VXB91_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HEV0471316.1"
                     /translation="MTQGKIIKVSGPLVIASGMQEANIQDICRVGKLGLIGEIIEMRR
                     DQASIQVYEETSGLGPGEPVVTTGEPLSVELGPGLISQMFDGIQRPLDRFKLATHNDF
                     LVRGVEVPSLDRDIKWHFDSTIAIGQKVSTGDILGTVKETEVVNHKIMVPYGVSGEVV
                     SIASGDFTIDEVVYEIKKLDGSFYKGTLMQKWPVRKARPVSKRLIPEEPLITGQRVID
                     AFFPVTKGGAAAVPGPFGAGKTVVQHQVAKFANVDIVIYVGCGERGNEMTDVLNEFPE
                     LIDPNTGQSIMQRTVLIANTSNMPVAAREASIYTGITMAEYFRDMGYSVAIMADSTSR
                     WAEALREMSGRLEEMPGDEGYPAYLGSRIAEYYERAGRSQVLGLPEREGTITAIGAVS
                     PPGGDISEPVTQNTLRIVKVFWGLDAPLAQRRHFPAINWLTSYSLYKDSVGTYIDGKE
                     KTDWNSKITRAMNYLQRESSLEEIVRLVGIDSLSDNERLTMEIAKQIREDYLQQNAFD
                     SVDTFTSFAKQEAMLSNILTFADQANHALELGSYFTEIMEGTVAVRDRMARSKYVSED
                     RLDEIKIISNEITHQIHLILETGGL"
     gene            2470..3855
                     /locus_tag="VXB91_001922"
     CDS             2470..3855
                     /locus_tag="VXB91_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000111247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HEV0471317.1"
                     /translation="MSVIKEYRTASEVVGPLMIVEQVNNVSYNELVEIQLHNGEIRRG
                     QVLEIHEDKAMVQLFEGSSGINLEKSKIRFAGHALELAVSEDMVGRIFNGMGKPIDGG
                     PDLIPEKYLDIDGQAINPVSRDYPDEFIQTGISSIDHLNTLVRGQKLPVFSGSGLPHN
                     ELAAQIARQATVLNSDENFAVVFAAMGITFEEAEFFMEELRKTGAIDRSVLFMNLAND
                     PAIERIATPRIALTAAEYLAFEKDMHVLVIMTDMTNYCEALREVSAARREVPGRRGYP
                     GYLYTNLSTLYERAGRLVGKKGSVTQIPILTMPEDDITHPIPDLTGYITEGQIILSHE
                     LYNQGYRPPINVLPSLSRLKDKGSGEGKTRGDHAPTMNQLFAAYAQGKKVEELAVVLG
                     ESALSDVDKLYVRFTKRFEEEYINQGFYKNRNIEDTLNLGWELLSILPRTELKRIKDD
                     LLDKYLPLVEV"
     gene            3878..4489
                     /locus_tag="VXB91_001923"
     CDS             3878..4489
                     /locus_tag="VXB91_001923"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000251933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HEV0471318.1"
                     /translation="MVRLNVKPTRMELNNLKERLTTAERGHKLLKDKRDELMRRFISL
                     IRENNQLRKEVESYLIDNLKSFAVAKSLKNSQMVEELFSIPSKEIELFVEKENIMSVT
                     VPRMHMNITSQNENSEYSYLSSNSEMDDVFATMNSLIYKLLRLAEVEKTCQLMADEIE
                     KTRRRVNGLEYSIIPNLSETIHYIELKLEEAERANLVRIMKVK"
BASE COUNT         1548 a          676 c          998 g         1491 t
ORIGIN      
        1 atatacattg tagaaaatca agaaatattt gtgtggttca ataaaataaa tccaagctta
       61 gattcaatct tttcaactta cgaattgaag atgcaggacg caacaatttc atcttctgag
      121 ttagaatttt tatgtgattt actattgtat aaaactttag atcaaggaag gtataatgta
      181 gatgggccgt tagttcttgc tagatattta ttgggatgtg agtttgaagt aaagaatctt
      241 agaatgatca tatcagctct tcaaaataca attccttttg aatcaataaa agaaaggata
      301 cgcccgcatt atggaagcta ataagtataa aattggcata attggtagcc atgatattat
      361 tttacccttt agcatgattg ggtttgatat attttctgcc tatcaagaac aagaagctat
      421 aaatactcta agaaaattag ctcaatctga ttatggtgtc atttatatca ctgaagacat
      481 tgcttcaatg atattagata caattcgcca ttatgattct caagttgtgc ctgctattat
      541 tttattaccg actcataaac aaggtttaaa tttaggatta aaacgtatag aggataatgt
      601 agagaaagca gtaggacaca atattttata ataatgtaca aaattgtctg taatattatt
      661 ctataatttt tggacttagt aaggagaata actttgactc aagggaagat tataaaagta
      721 tcgggacctc tagttattgc atcaggtatg caggaggcta atattcaaga tatttgccgt
      781 gtaggtaagc tagggttaat cggtgaaatt attgaaatga gaagagatca ggcatctatc
      841 caagtctatg aagaaacatc tggtcttggt ccgggagaac ctgttgttac aactggagaa
      901 cctctctcgg ttgaattagg gccaggattg atttctcaaa tgtttgatgg catacaacgc
      961 ccattagatc gatttaaatt ggctactcat aatgattttc tagttcgtgg ggtagaagtt
     1021 ccaagtttgg atagagatat taagtggcat tttgattcca ctatagcaat tggtcaaaaa
     1081 gtgagtacgg gtgatattct tggaactgtc aaggaaaccg aggtagttaa tcataaaatt
     1141 atggttcctt atggagtatc tggagaagtc gtttctattg catctggcga ttttacaatt
     1201 gatgaagttg tatatgaaat aaaaaaattg gacggtagtt tctataaagg aacgcttatg
     1261 caaaaatggc ctgtccgcaa ggcgcgtcct gtttctaaac gtttaattcc agaagaacca
     1321 ttaatcacag gtcaacgagt tattgatgca ttctttccag taaccaaagg gggagctgca
     1381 gcagttcctg gaccgtttgg agcaggaaag acagttgtac aacaccaagt agctaaattt
     1441 gccaatgttg atattgttat ttatgtcggt tgtggagaac gtggaaatga aatgacggat
     1501 gtactgaatg agtttcctga gttgattgac cctaataccg gacaatcaat tatgcaacgg
     1561 acagttctga ttgctaatac ttcaaatatg cctgttgctg ctcgtgaggc ttcaatttat
     1621 acaggaatta ccatggctga gtattttcgt gatatgggct actctgtcgc cattatggct
     1681 gattcaactt cacgttgggc agaagcgcta cgtgaaatgt caggacgtct agaagaaatg
     1741 cctggtgatg agggttatcc tgcttatctg ggaagtcgta tcgctgaata ttatgaaaga
     1801 gcaggacgtt ctcaggttct agggcttcca gaacgtgaag gaacgattac tgctattgga
     1861 gctgtatcgc cacctggtgg agatatttca gaaccagtta ctcaaaacac tttacggatt
     1921 gtgaaagttt tttgggggct tgatgctccg ttggcacagc gacgtcattt tcctgcaatt
     1981 aactggctta catcttattc actatataaa gacagtgtgg gcacttatat agatggtaaa
     2041 gagaagacag attggaatag taaaataact cgtgcgatga actacttaca acgggaatct
     2101 agtttagagg aaattgttcg tcttgttgga attgattctc tgtctgataa tgaacgacta
     2161 acgatggaaa ttgctaaaca aattcgagaa gattatttgc aacagaacgc ttttgattcg
     2221 gtagatacat tcacttcgtt tgcaaaacaa gaagcaatgc taagtaatat tctcactttt
     2281 gctgatcagg caaatcatgc tttagagttg ggttcttact ttacagagat tatggaaggt
     2341 accgtggcag ttcgagaccg tatggcgaga agtaaatatg tttcagaaga tagattagat
     2401 gaaatcaaaa ttatatcaaa tgagattaca catcaaattc atttgatatt agaaacagga
     2461 ggtctataaa tgagtgttat aaaagaatac agaactgcta gtgaagttgt tgggcctctt
     2521 atgattgttg aacaagtaaa taatgtgtct tacaatgagt tagttgaaat tcaacttcat
     2581 aatggagaaa ttcgtcgtgg acaagtttta gagatccacg aagataaagc aatggttcag
     2641 ctttttgaag gatctagtgg aataaattta gaaaagtcta aaattcgttt tgctggtcat
     2701 gcattagaat tggctgtatc tgaggatatg gttggtcgta tttttaatgg gatgggaaaa
     2761 ccaattgatg gtggaccaga tttaattcca gagaaatatt tagatattga tggtcaagct
     2821 attaatcctg tatctagaga ttatccagat gaatttattc agacagggat ctcctctatt
     2881 gatcatttga atactcttgt acgtggtcaa aaattaccag tattttcagg ttcgggctta
     2941 cctcataatg aattagctgc tcagatagca agacaagcga ctgttttaaa ttctgatgaa
     3001 aattttgcgg ttgtatttgc agcaatgggt attacttttg aagaagctga gttttttatg
     3061 gaagaactca gaaaaacagg agcgatcgat cgttcggttt tatttatgaa cttggcaaat
     3121 gatcctgcaa ttgagcgtat tgcaactccc cgcattgctt taactgcggc agagtatcta
     3181 gcttttgaaa aagatatgca cgttctagtt atcatgacgg atatgactaa ctattgtgaa
     3241 gcgttacgtg aagtctcggc agctcgccgt gaagttccag ggagacgagg ctatccggga
     3301 tatttatata caaatttatc aactctatac gaaagggctg gtcgcttagt tggtaaaaaa
     3361 ggttcggtga cacagattcc tattttaaca atgccagaag atgacataac acatccaatt
     3421 cctgatttaa ctggatacat tactgaaggg caaattattt tgtcgcatga gttgtataat
     3481 caaggttatc gtccaccaat caatgtttta ccttctctct ctcgattaaa agataaggga
     3541 tctggagaag gtaaaactcg tggagatcat gctccaacta tgaatcaact gtttgcagcc
     3601 tatgcccaag ggaaaaaggt tgaagagtta gcagtagtat taggagaatc ggctttatct
     3661 gatgtagata aattgtatgt gaggtttaca aagcgttttg aagaagagta cataaaccaa
     3721 ggattttata aaaatcgaaa tatagaagat acgttgaatc ttgggtggga attactatca
     3781 attcttccta gaacagagtt aaaacgtatc aaagatgatt tgcttgataa atacttacct
     3841 ttggtagaag tttaatccgg aaatggagtg attatctatg gtacgtttga atgtaaaacc
     3901 aactcgtatg gaattgaata acttaaagga acgtttgaca acagctgaac gtggacataa
     3961 gttattaaag gataaaagag atgaattgat gaggcgattt atttctttga ttcgtgagaa
     4021 taatcaactt cggaaagaag tggaaagtta tctaattgat aatctaaaat cctttgcagt
     4081 tgctaaatca ttaaagaatt ctcaaatggt ggaggaatta ttttcaattc catcgaaaga
     4141 aattgaatta tttgttgaga aagaaaatat catgagtgta acagttccta gaatgcatat
     4201 gaatattact tctcaaaatg agaacagtga atacagctat ttatcttcta atagtgaaat
     4261 ggatgatgta tttgctacaa tgaatagttt aatttataaa ttactaagac tggcagaagt
     4321 tgaaaaaacg tgtcagttaa tggctgatga aatagaaaaa acacgtagac gtgtaaatgg
     4381 tttagaatac tcgattattc caaacttgtc ggaaactatt cattatatag aattgaaact
     4441 agaggaggca gaaagagcca atttagttcg tattatgaaa gtgaagtaga tcctttattt
     4501 agattattaa ttagatgaac aaatatcagc ttggataagg ctttaagcct ttctaagctt
     4561 tttttattga cagtatcagg atatcttttt caaaattttg gtttgttaga taatgaaaat
     4621 gtttctacta atctagattt aggattagta aatcgtaaat gtaattatat agaaagtaag
     4681 tgcgtcataa caaggtatct atcattcatg gag
//
LOCUS       DAVLBE010000087         4699 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.087, whole genome shotgun sequence.
ACCESSION   DAVLBE010000087 DAVLBE010000000
VERSION     DAVLBE010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4699)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4699)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4699
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.087"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(188..259)
                     /locus_tag="VXB91_001924"
     tRNA            complement(188..259)
                     /locus_tag="VXB91_001924"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(224..226),aa:Arg,seq:cct)
     gene            complement(301..648)
                     /gene="rplS"
                     /locus_tag="VXB91_001925"
     CDS             complement(301..648)
                     /gene="rplS"
                     /locus_tag="VXB91_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HEV0471319.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            complement(767..1096)
                     /gene="crcB"
                     /locus_tag="VXB91_001926"
     CDS             complement(767..1096)
                     /gene="crcB"
                     /locus_tag="VXB91_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEV0471320.1"
                     /translation="MVIVYLAIACGLGALVRYFFSRYNQASKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVA
                     IFLGILL"
     gene            complement(1090..1464)
                     /gene="crcB"
                     /locus_tag="VXB91_001927"
     CDS             complement(1090..1464)
                     /gene="crcB"
                     /locus_tag="VXB91_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEV0471321.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIYLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYLSLI
                     LYLLLSIGGGLLLAYYLGRKKW"
     gene            complement(1461..1727)
                     /locus_tag="VXB91_001928"
     CDS             complement(1461..1727)
                     /locus_tag="VXB91_001928"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HEV0471322.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREAVIFEKVRSRVEDKRYQETIVATFSDILKRSRDYQDQNIK"
     gene            complement(1843..2286)
                     /locus_tag="VXB91_001929"
     CDS             complement(1843..2286)
                     /locus_tag="VXB91_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HEV0471323.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSTGAEKGSECVKVDLSAEEEDIERLEQFAEELAAKVG"
     gene            2390..3325
                     /locus_tag="VXB91_001930"
     CDS             2390..3325
                     /locus_tag="VXB91_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HEV0471324.1"
                     /translation="MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQKILKQYNITDAETAAIVGAPGRIDRVSLWGIFVEQADGHYRVRLRSKVHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            3379..3663
                     /locus_tag="VXB91_001931"
     CDS             3379..3663
                     /locus_tag="VXB91_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HEV0471325.1"
                     /translation="MARKETMAERKYCKMKKDIHPEYRPVVFMDTTTGYQFLSGSTKR
                     SNETVEFEGETYPLIRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(3720..3938)
                     /locus_tag="VXB91_001932"
     CDS             complement(3720..3938)
                     /locus_tag="VXB91_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0471326.1"
                     /translation="MSISPRFETLEQAIASKDLEKVREAFKKMNSTWTINESVVRDNS
                     IAHYGRVETAISFLPSSMEIEPTDESGT"
     gene            complement(3935..4686)
                     /locus_tag="VXB91_001933"
                     /pseudo
     CDS             complement(3935..4686)
                     /locus_tag="VXB91_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         1457 a         1014 c          833 g         1395 t
ORIGIN      
        1 agaacttgac gattttgaat aaattgacta tacaaacatt tatatactcg atatagtctc
       61 aattttatct gatgattgcc caaatttttc aataataaaa cgcataatat tatggagaca
      121 atcccctata ttatgcgttc ttttaatatc aaagactttt tgacaaactt cttcgatatc
      181 taattactgc cccctgcagg aatcgaacct gcaactactc cttaggaggg agttgttata
      241 tccattgaac taagggagct agataaaaac tctgctgaaa agcagagttt tttagtcgaa
      301 ttaacgacgg atttctttga tacgagctgc cttaccttga agagcacgca agtagtacaa
      361 tttcgcacga cgtactttac cgtaacgaac aacttcgatt ttttcaacac gtggagtgtg
      421 gattgggaag atacgctcaa cacctacacc gttagagatt ttacgaactg tgtagttttc
      481 tgagattcca gcacctttac gtgcgataac aacaccttca aaaatctgga tacgttcacg
      541 gttaccttcg acaactttcg catgtacacg aacagtgtca ccaggacgga atgatgggat
      601 atctgtacga agttgacctt cagtcaagct ttggattaat ggattcattt tattctccta
      661 tctttgtcaa tcttgaggaa tcttcctcag cggataaact gtatttttgt gcgtccatta
      721 cacacaagat atagtttacc aaatttctaa aaaaaagtaa agaaatttat agcaaaattc
      781 ctaaaaaaat cgcaaccaaa ccacctatgt aagtcaaagt caggtaagaa taaaagacct
      841 tcttatcact tagcagtctt tgaagttcgt cattcaaggt cgaaaaagtt gttaaaccgc
      901 cacaaaatcc tgttgctaga atagcatata cttccttaga ctctacatga ttgtagaata
      961 ctccaattaa aaaacaacct aaaagattag ctatgagcgt tccgagtggc aatttagaag
     1021 cttgattata gcgagaaaag aaataccgta cgagtgctcc caagccacag gcgattgcaa
     1081 gatagacgat taccatttct tcctccccaa atagtaagct aaaagcaggc ctccaccgat
     1141 actcaaaagc aaatacagta tcaaactaag ataacgccct gtatcaagca gcttcacagt
     1201 atcaagcatt aggctggaaa aagttgttaa acctccgcaa aaacccgtcc ccagtgctaa
     1261 aatcaagccc ttactagtcc ccttatagac cagatagccc ttgacaagat aaatcaagca
     1321 gaaaattccc agatagttga caaagagagt gccccaaggg aaatctggac tggctggtaa
     1381 ccaagtggaa actaggtagc ggacaagtcc gcccaacata gcagctagaa aaatccctag
     1441 cggataaaat tgttcttttt tcatttgata ttttgatcct gataatcacg cgaacgtttg
     1501 agtatgtccg aaaaagtcgc gacaatagtc tcctgatagc gcttgtcctc tacacgactt
     1561 ctaacctttt caaaaataac tgcttctctc ttagtatcta aaatcggttt ccctgaagcc
     1621 ttcttataag cgacaactcc ttcaactaag tgcattcgtt cttctaacag tttgacaatt
     1681 tggtcgtcga tttgatcgat ttcttgacga ataatatcta aatccataca gtctcctcct
     1741 ttatttgaat tattgtatca aaaagccatc aattaggcta gtaaaatccc aactctcgat
     1801 aagaaaaatg cactgattga ttacatcagc gcacttttat gcttatccta ctttagcagc
     1861 caattcttct gcgaattgtt ccaagcgttc aatatcttct tcctcggcag aaagatcaac
     1921 tttaacacac tctgaacctt tttctgctcc tgttgacaca aagacacggt caaagtcatc
     1981 aacagcctta caaaattcat cgtagaaggt atctcctgag ccgaccactc cgtagatttt
     2041 gccattcaag ttgagatctg ctaggtcttc gtagaagtcc atcatctcat ctggcaattc
     2101 accatcacca taagtatagg tcgcaacgat agcgatgtct gcttccaaga agtctgaagc
     2161 gtcaacagtt gtacattcat caacatcaac atccaagccc aagtcacgta atttgtctgc
     2221 tacaatatct gcaatttctt cggtattacc ggtcatactg gcaaatacaa tttttgctaa
     2281 tgccatatcg tcctcctcaa tttatctttc tccattatat cacatctttt tcattttaaa
     2341 aataaaaatt cttgtgctac aatgaaatga gaaagaattg aggttattta tggagatttg
     2401 ccaacaaatt ttagaaaaaa ttaaagaata cgacaccatt atcattcatc gtcatatgaa
     2461 accagaccct gatgccttgg gaagtcaggt gggattgaaa gccttgctag aacatcattt
     2521 cccagaaaaa accatcaaag ccgtcggttt tgatgaacca actcttactt ggatggctga
     2581 gatggatctt gttgaagata gagcctacca aggcgcactt gtcatcgtct gtgatacagc
     2641 taatactgct cgtatcgatg ataagcgcta tagtcaaggt gattttctca ttaagattga
     2701 ccaccatcca aatgatgatg tatacggtga cctgtcttgg gtcgatacta gttcaagtag
     2761 cgctagcgag atgattaccc tatttgccca aacaacccaa ctagccttgg cagatcgcga
     2821 tgctgagttg ctctttgcag gaattgtcgg tgatacaggt cgcttcctct acccttctac
     2881 cactgcacgg actcttcgcc tggctgctta tttgagagaa cataactttg actttgcggc
     2941 tctcactcgc aaaatggaca ctatgagcta caaaattgct aaactgcaag gctacatcta
     3001 cgaccatctg gaagtggatg aaaatggtgc tgctcgcgtt atcctgagtc agaaaatctt
     3061 gaaacaatac aatataaccg atgctgaaac tgcggccatt gtaggtgcac ctggacgcat
     3121 tgacagagtg agtctctggg gaatttttgt cgaacaggct gatggccact accgagttcg
     3181 cttacgcagt aaagtccatc ctatcaatga aattgccaag gagcatgatg gtggaggcca
     3241 ccctctagca agtggtgcta attcctatag cctagaagaa aacgaaatca tctaccaaaa
     3301 gttaaaaaac ttgcttaaaa actgataaaa tacttgccaa acttttcaga atctgataga
     3361 ctagtatagt aacaatctat ggctcgcaaa gagaccatgg cagaaaggaa atattgcaaa
     3421 atgaaaaaag atatccatcc agaatatcgc ccagttgtct tcatggacac aactactggt
     3481 taccaattcc ttagcggttc aacaaaacgc tctaacgaaa cagttgagtt cgaaggcgaa
     3541 acttacccat tgatccgtgt ggaaatttca tcagactcac acccattcta cactggacgt
     3601 caaaagttca ctcaagcaga tggacgcgtg gatcgtttca acaaaaaata cggtctcaaa
     3661 taatgataag agaacagttt tggctgttct tttttgtttc ttgaaatcaa ctgctgtttt
     3721 catgttccag actcatctgt aggttcgatt tccatgctac taggcaggaa ggaaatagct
     3781 gtttcaacac gtccataatg agctatacta ttgtcacgaa ccacactttc attgatggtc
     3841 caagtggaat tcattttctt aaaagcttct cggacttttt ccaaatcttt ggaggcaatg
     3901 gcctgctcta aggtttcaaa acgaggactt atactcatct gctttcaaaa agcattctag
     3961 tccatctccg attaccgatg gactttatca cctccttctc cagtccttgt atgacatctt
     4021 gaagttgatt catgacatct tccaaagttc gaaaggcttt attcttaaat ccacgtttac
     4081 gaatctcttt ccacacttgt tcaatgggtt catctctggt gtgtatggag gaataaaggt
     4141 aaaatcaata ttagtcggaa tatttaaggt acttgattta tgccatatag cattgtccat
     4201 aacgagtaaa aggataagct tgtgaaagct cttctaaaaa ggcgttcatc cacactcctt
     4261 tttataaacc tgaaataagg catcaattgt aacaaattct cctgcctctg tagccttcaa
     4321 atgacgggca agaaaggctt tctcttcctc aactgtcata tatgcatggt tacgaccacc
     4381 acgtgtttct tgaaggagag agtcgagtcc gaactcctca tattttttta cgtttcgcca
     4441 aatcgttgtt tgattacagt ctaaaagctc tataatctct ttataagatt tgcccatcag
     4501 acgaaatata gtagattgaa actagaatag tacacctcta cttctaaaac attgttagaa
     4561 atcaatttgt cctgttcttg tttcatttta ctatagaacg atttgaaggc gtttataata
     4621 tttagctgta cgagagtctt ttaaaagtgt tttgatggtt tggatttctt ctttagttga
     4681 tttcatatta ctattatat
//
LOCUS       DAVLBE010000088         4632 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.088, whole genome shotgun sequence.
ACCESSION   DAVLBE010000088 DAVLBE010000000
VERSION     DAVLBE010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4632)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4632)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4632
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.088"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            221..2830
                     /locus_tag="VXB91_001934"
     CDS             221..2830
                     /locus_tag="VXB91_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000386153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase"
                     /protein_id="HEV0471327.1"
                     /translation="MDYNFNLEHPFFFTNNDYSTDTSIKYQVSLPFNWHEVMNNDEWV
                     YQYPIGKFVERQGWKIHISSEYNSSHELLQDVAKICHEMRIPFKHLSTEDKFIMRNGK
                     LVSRGFSGKFITCYPNQNELESVLQRLESALKQYNGPYILSDKRWDEAPIYLRYGVFR
                     PSRDDEKKVAIDELIVGDEVVKDERLPVFKIPKGIVPPDFLNKWLDKKDKKQGDFPFI
                     IDNAIRFSNSGGIYNARLKEDGKKIILKEARPYTGLGFDGTYSSEKLASECKALKILN
                     EWSETPKIYWHGKIWEHTFLGIEHMKGVPLNRWVTNNFPLYEVVDKTKDYLLRVSKIV
                     EKLIDLTNKFHSENVYHQDLHLGNILVKDEDEISIIDWEQAVFSNDEKVVHKVAAPGF
                     RAWRETLPSEIDWYGIRQIAHYLYMPLVTTSDLTYNYVSQTRIEGKKLFESLGYTREH
                     IDYVESLLSYLDSKCPQIENISRKKVLKSMHEIRTIESEQDIQDFIIKLLRGFTLTYG
                     QWRKEFQSRFFPVHYYGLNFNQGIAFSDLAILWSYQQLAKKVKNFKFDDYYEIRTQVI
                     NEAVNNFKKSSLSGLFDGKIGTIWLIYEFGEIDRAVELFTTHFIEIFENSQNKNLYSG
                     QAGILLVGLYFLSKGEIDNKLGEEILIRLREYTLNYIENPETFCKVGASDVQSNDPYE
                     NFGGLLYGHAGVAWLFGEAYKLTGESIYKNGLELAVDKELVAYKVDSNNSLQYSQGHR
                     LLPYLATGSAGLLLLINRNKEILSSKYLKYLTSLERATDVVFCVLPGLFNGFCGLEVA
                     NNIYSDIDDNFSGQKKLIEQLYRYLCVIEEGFVIAGDNGLKITTDIASGFAGVAIGLV
                     SIMDNKLTILPQI"
     gene            2863..>4632
                     /locus_tag="VXB91_001935"
     CDS             2863..>4632
                     /locus_tag="VXB91_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S9 family peptidase"
                     /protein_id="HEV0471328.1"
                     /translation="MNQSNEIFLNTIQEKTHYKRSISSSFQELKKWNSLIFRRGRYWY
                     QFDNWSIPNTGVIKEWYVEDNDWIPKVSSSSLDNSNSLKIVFDVEKYTLPDDSILQDV
                     RISSDESYIVLVVSSLRSTNLIGIKKYTMEELFIIEDISVESSFYLGKFGVMYTRSKE
                     YGRPSKLFYKSFDSFTEEELFEENECSFRLKIVHIDSNNCFVKSVDFQKGRIFLYSFD
                     RTGFVRHSYTETVAPTPRDIALFSTEKAQYFLGISSTEEKKDQLILRETSSGDRVSIT
                     IPYQDRARRVHCIGRYILLDCSNAANSVFYLATFKNNSLRELSVNKITFDEKTTLYEN
                     SFSDRVLLFLERRTFYEKILSFDLIENTLKTEFERPIIKSNNTKYFSKVIWTKKDSYD
                     VSIPISLFWKSEDTDELPRRKKCILSVYGAYGKNDNSDLDEIMLSIIDAGFIYAIVHV
                     RGGGYLGGEWYRSGKALNKWNSIRDFIEGVNYLRENDVIDSKRLGLITSSAGGIIAGA
                     VLNEEKNLLQSILLFSPFINPYDTLQNPNDPLSKTEIAEWGDIRAPEVKAYIKSYSPM
                     QNIEKARDSNTVIVNILGEKDPYI"
BASE COUNT         1608 a          578 c          934 g         1512 t
ORIGIN      
        1 cgttgcggta actggagtgc ttttagttgg gaaaattgtt aattcattta aattgtaaac
       61 tttagagatt ctctggagtt atggatgtcg ttccaatatg tgcacgttgg aatgttagtg
      121 cttatatggg gagaatccaa aggattctcc ctttttattt aaataagtct gtctagctat
      181 agatatatta agtttgataa aatttcttgg agattttgtt atggattata atttcaattt
      241 ggagcatcct ttctttttca ctaataatga ttatagtaca gatactagca taaagtacca
      301 agtaagtctg ccttttaatt ggcacgaagt aatgaataat gatgagtggg tttatcaata
      361 ccctattgga aaatttgttg aaagacaagg gtggaaaata cacattagtt cagagtataa
      421 cagttcacat gaattgttac aagatgtagc aaaaatttgc catgaaatgc gaattccatt
      481 taaacatctt agtacagaag acaaatttat catgcgaaac gggaaattgg ttagtcgagg
      541 attttctggt aaatttatta catgttatcc aaatcaaaat gaattagagt cggttttgca
      601 aaggttagaa agtgccttaa agcaatataa tgggccatat attttaagcg ataaacgttg
      661 ggatgaagca ccaatatatc tgaggtatgg tgtgtttagg ccgtcaaggg atgatgaaaa
      721 gaaggttgct attgatgaat taattgttgg cgatgaagtt gttaaagatg aacgtttacc
      781 agtatttaaa attccaaaag gtatagtgcc ccctgacttt ttgaataaat ggcttgacaa
      841 gaaagataaa aaacagggag actttccctt tattatagat aatgcaatta gattttcaaa
      901 cagtggtggg atatataatg ctaggctaaa agaagatggg aaaaaaataa ttttaaaaga
      961 ggctagaccg tatacaggtc taggatttga tggtacttat tcttcagaga aattagcttc
     1021 ggagtgcaaa gcactaaaaa ttctaaatga atggagtgag acgcctaaaa tatactggca
     1081 cggtaagatc tgggagcaca ccttcttagg aattgaacat atgaagggcg ttccactaaa
     1141 tagatgggtt accaataatt ttcctttata tgaagttgtt gataagacca aagattatct
     1201 attgagagtt tcaaagatag tagaaaaact catcgattta acgaataagt ttcattctga
     1261 aaatgtatat catcaagatt tacatttagg aaatatcttg gttaaggatg aagatgagat
     1321 tagtataata gactgggaac aggctgtctt ttcaaatgat gaaaaagttg tacataaagt
     1381 tgcagcccct ggttttagag catggcgaga aacacttccc agtgagatag attggtatgg
     1441 tattagacaa atagctcatt atttatacat gccactagta actacatcgg atttgacata
     1501 caactatgta agtcaaacca ggatagaagg aaaaaaacta tttgagtctt tgggttatac
     1561 aagagaacat atagattatg tagaaagttt attgtcatat ctagattcta aatgtccaca
     1621 gattgagaat atttccagga aaaaagtttt aaaatccatg catgagatta gaactatcga
     1681 gagtgagcaa gatatacaag attttattat aaaattattg agagggttta cgctaactta
     1741 tggacagtgg cgtaaagaat ttcaatcaag attcttccca gttcattatt atggtctgaa
     1801 ttttaatcaa ggaattgcgt tttcagattt agctatcctt tggagttatc aacaactagc
     1861 taagaaagta aaaaatttca agtttgatga ctattatgag attcgaacac aggttattaa
     1921 tgaggcagta aataatttta agaaatcgtc cctttctggt ctttttgatg gtaaaattgg
     1981 tacaatctgg ctcatttatg aatttgggga gatagatcgg gcagttgaac tttttacaac
     2041 tcattttata gagatatttg agaattcaca aaataaaaat ttatatagtg ggcaggctgg
     2101 aattttactg gttggactgt attttcttag taaaggggaa attgataata aactaggaga
     2161 agaaatacta attaggctta gagaatatac tttaaattat atagaaaatc cagaaacttt
     2221 ttgtaaagtt ggcgctagtg atgttcagag taatgatcct tatgagaatt ttggtggatt
     2281 actatatggt cacgcagggg tagcttggct cttcggtgaa gcttataaat taactggtga
     2341 aagtatctat aaaaatggtc tagaattggc tgtagataaa gaattagttg cttataaagt
     2401 agatagtaat aattcattgc agtacagcca aggtcataga ttactaccat atctagcaac
     2461 tggaagtgct ggcctgcttt tacttattaa tagaaataaa gaaatcttgt caagcaaata
     2521 cttaaaatat ttaacttctt tagagagggc aactgatgta gttttttgtg tattaccagg
     2581 tttatttaac ggattttgtg gtcttgaagt tgctaataat atatatagtg atatcgatga
     2641 taacttttca ggacaaaaga aattaattga acaactttat agatatttgt gtgtaattga
     2701 agaaggattt gttattgcgg gagataatgg tttaaagata acaacagata ttgcttcggg
     2761 atttgcgggt gttgcaattg gattggtatc aataatggat aataaattga cgattcttcc
     2821 tcaaatataa tatttagata ccattattaa ggggtcatac ttgtgaatca gagtaatgaa
     2881 atatttttaa atacaataca ggaaaaaaca cactataaga ggtctatctc ttcatcattt
     2941 caggaattaa aaaaatggaa ttctttgata tttaggagag ggcgatattg gtaccaattt
     3001 gataattgga gtatacccaa tactggtgta ataaaggaat ggtatgtcga agataatgac
     3061 tggattccta aggttagttc ttccagttta gacaattcaa attcacttaa aattgtcttt
     3121 gatgtggaaa aatatacttt gccagatgat agtatcttac aggatgttag gatttcatct
     3181 gatgagagtt atatagtttt ggttgtatcc tcactgcgta gcactaattt aattggaata
     3241 aaaaaatata ctatggaaga gttatttatc attgaagata tttcagtaga aagttcgttc
     3301 tatttgggta aattcggtgt tatgtatact cgctccaaag agtacgggag gccaagtaag
     3361 ttattctata aatcttttga tagctttaca gaagaggaac tgtttgaaga aaacgaatgc
     3421 tcttttcgat taaaaatagt ccacattgat agcaataatt gttttgtaaa gtcagtagac
     3481 tttcagaaag gcaggatttt tctatacagt ttcgaccgga cgggttttgt tagacactct
     3541 tacacagaaa cggtagcccc aacacctaga gatatcgctc tatttagtac agaaaaagca
     3601 cagtactttc ttgggatctc ttcaactgaa gaaaagaaag atcaactaat tctaagggaa
     3661 acttcttcgg gagacagagt ttctattact ataccatatc aagatagggc tagaagagtt
     3721 cactgtatag gacgttatat ccttttagac tgttcaaacg cagcgaattc cgtcttttat
     3781 cttgctacat ttaaaaataa tagtttgagg gagttgagtg ttaataagat aacatttgat
     3841 gaaaagacaa cactttatga aaattcattt tctgatcgtg ttcttctgtt tttagagagg
     3901 agaacttttt acgaaaaaat acttagtttt gatttaatag aaaatacatt aaaaactgaa
     3961 tttgaaagac ccatcataaa atcgaataat actaaatatt tttctaaggt gatttggact
     4021 aaaaaagaca gttatgatgt aagcataccg atttctttat tttggaaaag tgaagatacg
     4081 gatgagctcc caagaagaaa aaaatgtatt ctaagtgtct atggggctta tggtaagaat
     4141 gataattctg atttagatga aattatgtta tctataatag atgcaggttt tatttatgct
     4201 atagttcatg taagaggtgg aggctatttg ggtggtgaat ggtatcgctc aggaaaggcg
     4261 ttaaacaaat ggaattctat cagagatttt attgagggag taaattattt aagggaaaat
     4321 gatgtaattg acagtaagcg attaggttta ataacttcta gtgcaggtgg aataattgct
     4381 ggtgcggtgt tgaacgagga aaaaaattta ttgcaaagca ttctcttatt ttcgccattt
     4441 ataaatcctt atgatacact tcagaatcca aatgatcctc tttctaagac cgaaatagca
     4501 gagtggggag atattagagc ccctgaagta aaggcttata taaagtcata ttcgcctatg
     4561 caaaatattg aaaaggcacg agactcaaat actgttatag ttaatatttt gggtgagaaa
     4621 gacccatata tt
//
LOCUS       DAVLBE010000089         4489 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.089, whole genome shotgun sequence.
ACCESSION   DAVLBE010000089 DAVLBE010000000
VERSION     DAVLBE010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4489)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4489)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4489
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.089"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(59..292)
                     /locus_tag="VXB91_001936"
     CDS             complement(59..292)
                     /locus_tag="VXB91_001936"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0471329.1"
                     /translation="MFSQLHMREEQVLLAQDYALETARAEGLEQGLERGKVEGRAERK
                     LFAFLDIVRQGLLTSEVASQQLGMSVSEFEALL"
     gene            complement(285..401)
                     /locus_tag="VXB91_001937"
                     /pseudo
     CDS             complement(285..401)
                     /locus_tag="VXB91_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233180.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
     gene            complement(616..966)
                     /locus_tag="VXB91_001938"
     CDS             complement(616..966)
                     /locus_tag="VXB91_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HEV0471330.1"
                     /translation="MLRHPGISPTNDLIAKKIFSNPEITCQFIRDMLDLPAKNVTILE
                     GSDIHVLLSMPYSVQDFYTSIDVLAELDNGTQVIIEIQVHHQNFFINHLWTYLCSQVN
                     QNLEKIRQREGDTH"
     gene            1222..3855
                     /gene="polA"
                     /locus_tag="VXB91_001939"
     CDS             1222..3855
                     /gene="polA"
                     /locus_tag="VXB91_001939"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HEV0471331.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDH
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEYGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNVSSADVAKGLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCEDKLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVETEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIVVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYMQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDNVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPDIKNYMDEVVREARDKGYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEMKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            3940..4377
                     /locus_tag="VXB91_001940"
     CDS             3940..4377
                     /locus_tag="VXB91_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HEV0471332.1"
                     /translation="MSQEFINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLPDVARDFLKADA
                     KIFWAQLGLESLEAKEILRDGGCDDIVMNRCIKREHTRLIEEA"
BASE COUNT         1224 a          833 c         1079 g         1353 t
ORIGIN      
        1 aaataggctc cataatatcc ataggggatt tacccactat ggatattatg gagccatttt
       61 acaacagtgc ctcaaattca gatactgaca tacctaattg ctggctggca acctcagaag
      121 tcagaagacc ttggcgtact atgtctagga aggcaaaaag tttcctttct gcccttcctt
      181 caactttccc acgctctagt ccttgttcaa ggccttcagc cctagcagtt tccaaggcat
      241 agtcctgtgc taacaagact tgttcttctc gcatatgtag ttgactaaac attttcctgt
      301 cctcctcgga ccagctcttg tagtccagca gttgatttgc ttggctaatg gctcgttgcg
      361 gttgctgggt aaagggcttg ttgccgaaaa actccaacca tggcttgcga accttgtctt
      421 tgctggtttc tctgtatttt ttaattccaa gaatgccatc ttaaccagat ggttttcctg
      481 tccattgttg gtaatcgcca atacctcacc tgttgtgtct tcgcgcatac taaagctatg
      541 aaaagccagg tcatctgaga aataattact atccacgata gcaatggcgt aaacaggagc
      601 gatgtgtttg tagctctagt gagtatcacc ttctcgctga cgaatttttt caagattttg
      661 attaacctga ctgcacaggt aagtccacaa gtgattgatg aaaaaattct gatgatggac
      721 ttgaatctca ataattactt gagtaccgtt atccaactcc gccaagacgt ctatactggt
      781 ataaaaatcc tgcaccgagt aaggcatgga gagtaatacg tgaatatcgc ttccctccaa
      841 aatggtcaca ttttttgctg gcaagtccag catatcgcga ataaattgac aagtgatttc
      901 tggattgctg aatattttct tagcaatcaa atcattagtt gggctgatgc ccggatgtct
      961 gagaatcctc ctattcctcc ttctatagtg agttgaaata agatgtgaat aactctatca
     1021 ggaaagtcaa attaatttat agaaatattt tagcagtcaa ggtgtactat tatagattca
     1081 atatattata ttatagcaca tttttaaatc taggtttact aaattctctg gctctatcta
     1141 tttattcgga aaaagtttga aaaatacttg ctctagctct tcccaatggt attttttgat
     1201 tctttccttt ataatgggtg tatggataag aaaaaattat tattgattga tgggtcttct
     1261 gtagcttttc gggcgttttt tgcgctgtat cagcagttgg accgttttaa gaatgcggct
     1321 ggtttgcata ccaatgcgat ttatggtttt cagttgatgt tgagtcattt gttggagcgg
     1381 gttgagccga gtcatatttt ggtggctttt gatgcgggaa agacgacctt ccggacagag
     1441 atgtatgcgg actataaggg tggtcgggcc aagactcctg atgagtttcg tgagcaattt
     1501 cctttcattc gtgagttgct ggatcatatg gggattcgtc actatgagct ggctcagtat
     1561 gaggcggatg acatcattgg gacgctggat aagctagcag agcaggatgg ttttgatatt
     1621 accattgtca gtggggacaa ggatttgatt cagctgacgg atgagcatac ggtggttgaa
     1681 atttccaaga aaggtgtggc tgagtttgag gcctttacgc cagattacct catggaagaa
     1741 atgggcctca caccagctca gtttatcgat ctcaaggcgc tcatgggtga taagtcggat
     1801 aatatccctg gggtgaccaa agtcggtgaa aagacgggta ttaagctctt gctggagtat
     1861 ggttcgcttg aggggattta tgaaaatatt gatggaatga agacttctaa gatgaaggaa
     1921 aatctcatca atgacaagga acaggccttt ttgtctaaaa cactagcgac cattgatacc
     1981 aaggcaccga ttgcgattgg tttagaggac ttggtctata gtggtccaga tgttgaaaat
     2041 cttgggaaat tttacgatga gatgggattc aaacagctca agcaggcttt aaatgtgtcg
     2101 tcagctgatg tggctaaggg tttggatttt actattgttg accaaatcag tcaagatatg
     2161 ctgagtgaag agtctatctt ccactttgag ctttttggtg agaattacca tacggataat
     2221 ttggttggat ttgcctggtc ttgtgaggat aagctctatg ccacagacaa gcttgagctg
     2281 ttgcaagacc cgattttcaa ggatttctta gaaaaaacat ctctgagagt ttatgacttt
     2341 aagaaggtta aagttctttt gcaacgtttt ggtgtggatt tgcaggcgcc tgcttttgac
     2401 atccgtttgg ctaaatacct cctttcgact gtggaggaca atgaaattgc gaccatcgct
     2461 agtctttatg gtcagactta cttggttgat gatgaaactt tctacggtaa gggtgttaaa
     2521 aaggccattc ctgaacgtga gaaattcttg gaacacttag cttgtaaact tgctgttttg
     2581 gtagaaacag agcctatttt acttgaaaaa ctcagcgaaa atgggcaatt agagcttctt
     2641 tatgatatgg agcaacctct ggcttttgtt cttgccaaga tggaaattgc tgggattgtg
     2701 gtcaagaaag agaccttgct tgagatgcag gctgaaaatg agcttgtcat tgaaaaactg
     2761 actcaagaga tttacgagct ggctggtgag gagtttaatg tcaactcgcc taagcagttg
     2821 ggcgtgcttc tctttgagaa attgggactt cctctagaat acactaagaa aaccaagaca
     2881 ggttattcga cagcagtgga tgtgttggag cgtctcgctc ctattgctcc gattgttaag
     2941 aaaatcctgg attaccgtca aattgctaag attcaatcta cttatgtaat tggcttgcag
     3001 gactggattt tggctgatgg aaagattcat actcgctata tgcaggattt gacccagacc
     3061 gggcgtttgt ctagtgtgga tccaaacttg caaaatattc ctgcccgatt ggaacaaggg
     3121 cgcttgattc ggaaggcttt tgtgccagag tgggaggata gtgtgctact cagctctgac
     3181 tattcacaga ttgaattgcg cgttttggcg catatttcta aggatgagca cttgattaag
     3241 gccttccaag agggggcaga tatccatact tcgacagcca tgcgggtctt tggcattgag
     3301 cgtcctgata atgtgactgc aaatgaccgt cgcaatgcca aggcagttaa ctttggagtg
     3361 gtttatggga tttcagactt tggcttgtct aataatttgg gaattagtcg taaggaagcc
     3421 aaagcctaca ttgataccta ctttgaacgt tttccagata ttaaaaacta catggatgaa
     3481 gtggtgcggg aggcgcgtga taagggctat gtagagaccc tctttaagcg tcgccgtgag
     3541 ttgccagata tcaattcgcg caacttcaat attcgtggtt ttgcggagcg aactgctatc
     3601 aactcaccta tccagggttc ggcagcagat attctcaaga ttgccatgat tcagctggat
     3661 aaagccttgg ttgcaggtgg ttatcagact aagatgctgt tacaagtgca cgatgaaatc
     3721 gtccttgaag tgcctaaatc tgaattggta gagatgaaaa aattggtgaa acaaaccatg
     3781 gaagaagcca ttcaactcag tgttcctctt atcgcagatg agaatgaagg ggcaacctgg
     3841 tacgaggcta aataaaaagg gggctagtcc tccttttttg tagtataatt ctgcaaacct
     3901 tttcaaaatg tgctatactg atgaaaaagg aggatttcta tgagtcaaga atttatcaat
     3961 ccaagtgatg gcgtgattcg tcagtatctc gcaacgagta aaacccttgc tgtggtgggt
     4021 ttgtctgacc gtgaagaaac aaccagcaat cgagtaacaa aggaaatgca ggctcggggc
     4081 tataaaatca tcccagtcaa tcccaaggcg gcaggtggcg aaatcttggg tgaaaaggct
     4141 tatgctagcc tcgctgaaat tccttttcct gtagatattg tcaatgttta tcgtcgcagt
     4201 gaatttctgc ccgatgtggc gcgtgatttt ctcaaagctg atgccaagat tttttgggca
     4261 cagctaggac ttgaaagttt agaagcgaaa gagattttgc gtgatggtgg atgtgatgat
     4321 atcgtgatga atcgctgtat caagagagaa catactcgct tgattgagga agcataagaa
     4381 aaaggtagct gatgggctac cttttgtgtt atactcaatg aaaatcaaag agcacactag
     4441 caaactagga aactagccgc gggctgctca aaacaccgtt ttgaggttg
//
LOCUS       DAVLBE010000090         4256 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.090, whole genome shotgun sequence.
ACCESSION   DAVLBE010000090 DAVLBE010000000
VERSION     DAVLBE010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4256)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4256)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4256
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.090"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(19..732)
                     /gene="rsmG"
                     /locus_tag="VXB91_001941"
     CDS             complement(19..732)
                     /gene="rsmG"
                     /locus_tag="VXB91_001941"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HEV0471333.1"
                     /translation="MKPETFYNLLAEQNLPLSDQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            826..1386
                     /locus_tag="VXB91_001942"
     CDS             826..1386
                     /locus_tag="VXB91_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEV0471334.1"
                     /translation="MTWIILGVIALIVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTPEEEKSVPKVDFSGLGD"
     gene            1388..2287
                     /gene="htpX"
                     /locus_tag="VXB91_001943"
     CDS             1388..2287
                     /gene="htpX"
                     /locus_tag="VXB91_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HEV0471335.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRVFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALASAITMLSSMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGFQKLFYTHPPISERIERLKHM"
     gene            complement(2436..3995)
                     /locus_tag="VXB91_001944"
     CDS             complement(2436..3995)
                     /locus_tag="VXB91_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV0471336.1"
                     /translation="MHYRHSRKGNSMIKINHLTITQNKDLRDLVSDLSMTIQDGEKVA
                     IIGEEGNGKSTLLKTLMGEDLSDFTIKGDIQSDYQSLAYIPQKLPEELKKKTLHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQEIGNLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYDSYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQNVETALRATKDSTAGR
                     LLAKKMKTVLSQEKRYEKAAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLS
                     IDDRVLVQKLQLTVRGQEKIGIIGPNGVGKSTLLAKLQRLLNDKREISLGFMPQDYHK
                     KLQLDLSPIAYLSKTGEKEELQKIQSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRFLKEVCSIIYRMTE
                     HGLKLVNLEDL"
BASE COUNT         1186 a          803 c          900 g         1367 t
ORIGIN      
        1 atttgtttac taaaaaattt aaagtgggcg tttatttggc ataccagcct tacgtggata
       61 tttatttggt gtttcttttt tcttttctac cactgtgata tagcgcggat ctctattcgg
      121 tagggcgtag ctgagattgt cttcgacctt actaaaaagg agattgaggg cattcttagc
      181 ttctaacaac tcctcaggcg cattgctagc cttgagtgct aatagtttgc caccaacctt
      241 aaggtaggga atagtcaatt cagataggac ctgcatacgg gcaaccgcac gagctgttac
      301 aaaatcatat tgagcacgga agttcttgtc ttgggcaaaa tcttcggcac gtccgtggta
      361 gaaatgaact ccgttcaaat ccagttcttg agccaagagt tgtaggaagt tgatgcgctt
      421 attgagtgaa tcaataatgg tcacatctaa ctccggatag agaattttca ttggtagact
      481 aggaaatcct gccccagccc cgatatcaag aagtttgata gtttcattgg gaatcaaacc
      541 ttgaagaatg ggtgcaatcg aatcgtaaaa atgtttgaga taaacttctt ccttgtccgt
      601 aatcgccgtc aaattaatct tctcattcca ctcgaccaag agctcaaaat aacgttcaaa
      661 ttgttctttt tgctggtccg aaagtggaag attctgctcg gcaagcaagt tgtaaaatgt
      721 ttctggtttc atagttattt ccttctttag tatcatctta ttttaccaca atcattaaaa
      781 atttgatata ctggtactaa tctaaaagta gaaaggactt atatcatgac ttggattatt
      841 cttggagtta tcgctcttat tgttattttt gtgattgtta gctataacgg tttggttaaa
      901 aatcgtatgc aaaccaagga ggcttggagt cagattgatg ttcagttgaa acgtcgaaat
      961 gacctcttgc caaacttgat tgagactgta aaaggttatg ccaaatatga aggttctacc
     1021 cttgaaaagg tggcagaact acgtaaccaa gtggcggcag cgacttcacc agcagaagct
     1081 atgaaagcca gtgatgccct cactcgtcaa gtttcaggta tttttgcagt tgcagaaagc
     1141 tatccagatt tgaaagctag tgctaacttt gttaaattgc aagaggagtt gacaaacaca
     1201 gaaaataaaa tttcttactc tcgtcaactc tataacagtg ttgtcagcaa ctacaatgta
     1261 aaattagaaa ctttcccgag caatattatc gctggaatgt ttggatttaa agcggcagat
     1321 ttccttcaaa cacctgaaga ggaaaagtcg gttcctaaag ttgattttag cggtttaggt
     1381 gactaagatg ttgtttgatc aaattgcaag caataaacga aaaacctgga ttttgttgct
     1441 ggtatttttc ctactcttag ctcttgttgg ttatgcggtt ggttatctct ttataagatc
     1501 tggacttggt ggtttggtta tcgcactgat tatcggcttt atctacgctt tgtctatgat
     1561 ttttcaatcg acagagattg tcatgtccat gaatggagcg cgtgaggtgg atgagcaaac
     1621 ggcaccagac ctctaccatg tagtggaaga tatggctctg gtcgctcaga ttcctatgcc
     1681 ccgtgttttc atcattgatg atccagcctt aaatgccttt gcgacaggtt ctaatcctca
     1741 aaatgcggct gttgctgcga cttcaggtct actagctatc atgaatcgtg aagaactaga
     1801 agctgttatg ggacatgaag tcagtcatat tcgtaattat gatatccgta tttcgactat
     1861 tgcagttgcc cttgctagtg ctatcaccat gctttctagt atggcaggtc gtatgatgtg
     1921 gtggggtgga gcaggtcgca gacgaagtga tgatgaccga gatggaaatg gtcttgaaat
     1981 cattatgcta gtggtttccc tactagctat tgtactggca cctctcgctg caaccttggt
     2041 tcagctcgct atttctcgtc agagggaatt tctggcagat gcatctagtg tcgagctgac
     2101 tcgcaatccc cagggaatga ttaatgccct agataagttg gacaatagca aacctatgag
     2161 tcgccacgtc gatgatgcta gcagtgccct ttatatcaat gatcccaaga aaggtggggg
     2221 gttccaaaaa ctcttttata cccacccacc tatctcagaa cggattgaac gtttaaaaca
     2281 tatgtaaaat gaaggctgga aaaaagtctt taaaatctga aaaacgcata atatcaggtg
     2341 tgaaaacttg atattatgcg ttttactatg ggaagattta cttctttttc tcctaaaatt
     2401 gtgtttttgc cccacctatc tgctatgttg caaatttata aatcttctaa attaactagc
     2461 ttcaaaccgt gttctgtcat gcgatagatg atcgagcaga cttcttttaa gaaacgacgg
     2521 tcatgcgaaa cagtgatgag accgccagga taagtggcaa agagttttct gatttggggt
     2581 tgagaagtgg gagaaaagtt tcgtgtgggt tcatccagca ggagaaagtt tggtttgcgc
     2641 aggactaaat ccaaaagcag gagttttccc tgttgtccgc cagataagga gcgaatttga
     2701 tgctgcattt ctggataact gaaattgaga ctagctaggt gagattggat tttctgtagt
     2761 tcctcttttt ccccagtttt actgagatag gctattgggg ataaatccaa ttgcagtttt
     2821 ttgtggtaat cttgtggcat aaaaccaagt gaaatctctc ttttatcatt cagaagtctc
     2881 tgtaacttgg ctaacagagt tgatttccca acaccatttg gcccgataat accgattttt
     2941 tcttggccac ggacagttag ttgtagtttt tgaaccaaaa ctcggtcgtc aatggacaaa
     3001 ttttcttttt ccagttggac taagacttta gaagctggta atggttggat gtctgaaaag
     3061 aaaagttgga tttgttcctc ttcaagtggt ttttgagtca tggactgagc tgccttttcg
     3121 tagcgttttt cttgtgagag gacagttttc atctttttag ccaataggcg accggcagta
     3181 ctatctttgg tagctcgaag cgcagtttct acattttgct taactctccg atgtttttcc
     3241 atggttttat cgtaggctct ttggttgtta gcagcttgct gactttgttt ggcaaaatta
     3301 gcctttctct gctcactata gctatcatag tctaaatgct ctactagcgt ttccgcttct
     3361 ttacggtgtt tgaccagtcg caagtgaaca atagtgtctg ccgtttcaga aagaaagtct
     3421 tcatcatggg aaatgaaaat aacggtttgc ctggtctttt gaatctggcc ttttagccaa
     3481 tcaactgtct caaggtctag gtcatttgaa ggttcatcta aaaatagaat ctcaaagggt
     3541 ttggctaact catggataag ctgaattttc aaagcttctc cccctgatag attgccaatc
     3601 tcttggtcac ttgcgaaacg attgctatca aaatgcaatt cctccgccaa acgatagagg
     3661 atactgtagt ctaaatcaat agaatctaaa aagaagtagt cgtgtaaagt tttctttttc
     3721 agctcctcgg gaagtttttg aggaatgtag gccagtgact gatagtcaga ttggatgtct
     3781 cccttgatag tgaaatcaga caaatcttcc cccattaaag ttttaagtaa ggttgattta
     3841 ccatttcctt cttcgccaat aatagctacc ttttccccgt cttgtatggt catgcttagg
     3901 tcagagacaa ggtctcgtaa atctttgttt tgtgtgatgg tcaggtgatt gatttttatc
     3961 atactattgc cctttctaga atgtcgatag tgcataacaa aaagctctac tttacctagt
     4021 agagcccaaa gtctatgtca aaaaaactct attaacatgc cagaaaaaga gcataaaaga
     4081 gcacacaaaa agagacaaaa acaagatcta ctaaataaag gttctttatt tgatagactt
     4141 agttgttcat gtctccctta cctccgagta ttagtatctt tatattatac ctttaaggaa
     4201 attttgtcaa cagaaaactg gaaattctat gctctaaaat ccaaaaacag gtccat
//
LOCUS       DAVLBE010000091         4136 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.091, whole genome shotgun sequence.
ACCESSION   DAVLBE010000091 DAVLBE010000000
VERSION     DAVLBE010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4136)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4136)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4136
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.091"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            720..1712
                     /locus_tag="VXB91_001945"
     CDS             720..1712
                     /locus_tag="VXB91_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0471337.1"
                     /translation="MAMIEVEHLQKHFVKIVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQDNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPNSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQKIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYEGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
     gene            1714..2532
                     /locus_tag="VXB91_001946"
     CDS             1714..2532
                     /locus_tag="VXB91_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HEV0471338.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVLYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            2534..3319
                     /locus_tag="VXB91_001947"
     CDS             2534..3319
                     /locus_tag="VXB91_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0471339.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLAQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLMLISLVFFVISLKLWDKGLDSYESAGS"
     gene            3417..3635
                     /locus_tag="VXB91_001948"
     CDS             3417..3635
                     /locus_tag="VXB91_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HEV0471340.1"
                     /translation="MKDLPEWFGIPESTQAYIEGTTTLQVWTAYQESDLTGFVRLSYS
                     SEDCAEIDCLGVKKLIKVEKLGANCLLL"
     gene            3620..3781
                     /locus_tag="VXB91_001949"
     CDS             3620..3781
                     /locus_tag="VXB91_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEV0471341.1"
                     /translation="MLATLESEARKKVGYLQVKTVAEGSNKDYDRTNDFYRGLGFKKL
                     EIFSQLWNP"
BASE COUNT         1154 a          703 c          895 g         1384 t
ORIGIN      
        1 gctatatatt atggtatcga atcttcatca gaatgataaa attaatcaat taatatctga
       61 ttacaaacag aatatgaaag ctttttatat cactattgaa aaatttatac gagatgatga
      121 aagccttaag tgttatttta caaaggttat ttcaagtcgt tccaaggtaa caagtctaga
      181 tcagattgaa gctgataaaa cgatacaaag aaaatattca agtgagctaa aaaaatttat
      241 tggattttat aatgagatta tttgtgagga aaatagtttc ctacatgtac gaaagaggtg
      301 gtcgagttgg tttaggtagt cggtgcgtga gttgataatt ctcagggtat ggacttcttt
      361 ttcatgaatg aggtaaaaga gcaggtattg tttagagaca atcattctga gcatattttc
      421 tggatagagg gagtatccga ttttatgatc aaagttaata ccgccctctg gtgagaagat
      481 gagtaggttg gtaatttaaa ctattaaaca gaatttttga ttaaaagtat tatttcatga
      541 gagaaatcct aatttcacaa tctataggca aacgcttgca tttcgttttt tattggacta
      601 taataggttg gtataaagcc ttctgtagta ataaaatgta gaaggtgtag aaagtaagga
      661 tttagaatat ttgtagttaa aaacacaatg ttgctattcc ttacgatagg gagatagata
      721 tggcaatgat agaagtggaa catcttcaga aacattttgt gaagattgtt aaggaaccgg
      781 gcttgaaggg ggctttgcgc tcctttattc atcctgaaaa gcagaccttt gaagcggtca
      841 aggatttgac ctttgaggtt ccaaaagggc agattttagg atttatcggg gcaaatggtg
      901 ctgggaagtc gacaaccatt aaaatgctga caggaatttt gaaaccaaca tctggttttt
      961 gtcggattaa cggcaagatt ccccaggaca atcggcaaga ttatgtcaaa gatattggcg
     1021 tagtctttgg acaacgcacc cagctatggt gggatttggc tctgcaagag acctacactg
     1081 tcttaaaaga gatttatgat gtgccaaact cgctctttca taagcgtatg gactttttga
     1141 atgaagtctt ggatttgaag gactttatca aggatcccgt gcggactctt tcactgggac
     1201 aacggatgcg agcggatatt gcggcctcct tgctccacaa tcccaaggtt ctttttttag
     1261 atgagccgac cattggtttg gacgtttcgg ttaaggataa tattcgtcgg gcaattactc
     1321 agatcaatca agaggaagaa actaccattc ttttgaccac tcacgatttg agtgatattg
     1381 agcaactttg tgatcggatt ttcatgattg acaaggggca aaagattttt gatggaacgg
     1441 tgagccaact caaggagacc tttggtaaga tgaagactct ctcttttgaa ctgctaccag
     1501 gtcaaagtca tctcgtctct cactatgaag gtctgtctga tatgaccatt gatagacaag
     1561 gaaacagcct caacattgaa tttgatagtt ctcgctacca gtcagctgac attatcaagc
     1621 aaaccctatc tgattttgaa atccgcgatt tgaagatggt ggatacggat attgaggata
     1681 ttatccgtcg cttctaccga aaggagctct aggatgatca aattgtggag acgttataaa
     1741 ccctttatca atgcaggggt tcaggagttg attacttacc gagtcaactt tattctctat
     1801 cggattggcg atgtcatggg ggcttttgtg gccttttatc tctggaaggc tgtctttgat
     1861 tcttcgcaag agtctttgat tcagggcttc agtatggcgg atatcaccct ctacatcatc
     1921 atgagttttg tgaccaatct tctgactaga tccgattcgt cctttatgat tggggaggag
     1981 gtcaaggatg gctccattat catgcgtttg ttgcgaccag tgcattttgc ggcctcctat
     2041 cttttcaccg agcttggttc caagtggttg atttttatca gcgttggcct tccattttta
     2101 agtgtcattg tcttgatgaa aatcatatcg ggtcaaggta ttgtagaggt gctaggatta
     2161 actgtccttt atctttttag cttaacgctc gcctatctga ttaacttttt ctttaatatt
     2221 tgctttggat tttcagcctt tgtgtttaaa aatctttggg gttccaacct acttaagact
     2281 tccatagtgg cttttatgtc ggggagttta attcccttgg cattctttcc aaaggttgtt
     2341 tcagatattc tctccttttt gcctttttcg tccttgattt atactccagt tatgatcatt
     2401 gttggaaaat acgatgccag tcagattctt caggcactcc ttttgcagtt cttctggctc
     2461 ttagtgatgg tgggattgtc tcagttaatt tggaaacggg tccagtcctt tatcaccatt
     2521 caaggaggtt agtatgaaaa aatatcaacg aatgcatctg atttttatca gacaatacat
     2581 caaacaaatc atggaatata aggtggattt tgtggttggt gtcttgggag tctttctggc
     2641 tcaaggcttg aatctcttgt ttctcaatgt catctttcaa catattccat tcctagaagg
     2701 ctggaccttt caagagatag ctttcattta tggattttcc ttgattccca agggaatgga
     2761 ccatctcttt tttgacaatc tctgggcact agggcaacgc ctagtccgaa aaggagagtt
     2821 tgacaagtat ctgactcgtc ccatcaatcc tctctttcac atcctagttg aaacctttca
     2881 gattgatgcc ttgggtgaac tcttagtcgg tggtatttta ttgggaacaa cagtgaccag
     2941 cattgtttgg actcttccaa aattcctgct tttcctagtt tgtattcctt ttgcgacctt
     3001 gatttatact tctcttaaaa tcgcaacagc cagtatcgcc ttttggacta agcagtcagg
     3061 cgccatgatt tacatcttct atatgttcaa tgactttgct aagtatccga tttctattta
     3121 caattctctt cttcgttggt tgattagctt tatcgtgcct ttcgccttta cagcctacta
     3181 tccagctagc tatttcttac aggaaaagga tgtgttcttt aacgtaggag gtttgatgtt
     3241 gatttctctg gttttctttg ttatttccct taaactttgg gataagggct tagattccta
     3301 cgaaagtgcg ggttcgtaaa agctaaagta agactaaaat caagaaagga acttatgatg
     3361 tttgtaattg aagaagtcaa ggatgaaaat caaaaaaggc agttgtcgtt gaggttttga
     3421 aggatttgcc agaatggttt ggaatcccag aaagcacaca agcctatata gaaggaacca
     3481 cgacactgca agtttggacc gcctatcagg agagtgattt gactggattt gtaaggttat
     3541 cctattcgag tgaagattgt gcagagattg attgtctcgg cgtaaaaaag cttatcaagg
     3601 tagaaaaatt gggagccaat tgcttgctac tttagagagt gaagctcgta aaaaagttgg
     3661 ttatctgcag gtcaaaacag tggcagaagg ttctaataaa gattatgatc gaacaaatga
     3721 cttttatcga ggtcttggct ttaaaaagtt agagattttt tctcagctat ggaatccgta
     3781 aaatccttgt cagattttga ttaaaaagct tgaataatat tacttgacat ctattctcag
     3841 agtgccatac tgtaagtgta atcgccgatt tagctcagtt ggtagagcaa ggcactcgta
     3901 aagcctaggt tataggtaga taaacgactg aggagttgaa aaaatagata ggtagaagat
     3961 aaccgttaag ccttattctt agcggttatt tatattgttt aatagcgctg atatttcatc
     4021 aattatgcct gttttcgtgt ttctggtagt tgttcaagtt tattgctact atttttgatg
     4081 gtatgaatgt gcttataatg tatcccggtt aacgaaagtt ttggacttat actcat
//
LOCUS       DAVLBE010000092         3984 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.092, whole genome shotgun sequence.
ACCESSION   DAVLBE010000092 DAVLBE010000000
VERSION     DAVLBE010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3984)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3984)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3984
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.092"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            1..665
                     /locus_tag="VXB91_001950"
                     /pseudo
     CDS             1..665
                     /locus_tag="VXB91_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001213952.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1497..1856
                     /locus_tag="VXB91_001951"
     CDS             1497..1856
                     /locus_tag="VXB91_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0471342.1"
                     /translation="MGQEIKLIRKQFRITRQEEKQIKEMMREQKVDSFSEFLRQNLLK
                     KNYQDRIFESWFSLWQSQKFEQISRDVYEVLVVARENHQVTQEHVSILLTCVQELIAE
                     VNQVQPLSREFREKYMG"
     gene            1866..2195
                     /locus_tag="VXB91_001952"
     CDS             1866..2195
                     /locus_tag="VXB91_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000263054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HEV0471343.1"
                     /translation="MVYRYRTNLKKVFLTDPELHQLNERIAKSNCQNFSVYARKVLLN
                     PNMSFVTINTDTYDQLVFELRRIGNNINQIARAINQSHLISQDQLQELSKGVGELIKE
                     VDKEFQV"
     gene            2218..3984
                     /locus_tag="VXB91_001953"
                     /pseudo
     CDS             2218..3984
                     /locus_tag="VXB91_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050775.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
BASE COUNT         1472 a          585 c          777 g         1150 t
ORIGIN      
        1 caagaatcat gggttaatca atggttaagt gaaaatatta taagtgagaa agatggaagt
       61 tatcaacatt cactgactat aatgaaggat ttcaataatc aaaaaatagt taactatatt
      121 gctcatttca atagttatga cattttgaaa aaaggttctc acttatcagg tgcatataaa
      181 cgaaaaattt tttctaaaga aaatacacga ttttggagtt taatattaac tcgaaagaat
      241 tttcgcaaca acttgatatt ctctataaag aagttggtgt attaagtttg ggacaaaaag
      301 ttgtagccat gcttgatttt ttattagcat atagtgatta ttctaaagac ttcagaccat
      361 tgattattga tcagcctgaa gacaatctag acaatcgtta tatttacagg catttagttc
      421 agcagtttag agatgtgaaa gctcaacgtc aaattatttt agtaacacat aatgctacaa
      481 ttgtaacaaa ttctatgaca gatcaagttg ttattatgga gtcagatgga gttaacggat
      541 ggattgaatc acagggatat gttagtgaaa aatatataaa aaatcatatc atcaatcaat
      601 tagagggagg aaaagattcc ttcaagcata aaatgtctat atatgagacg gctttatcag
      661 agtagagtca gaaaaagtag gttagaaatt tagcctactt ttttctttgt ccgacaggca
      721 tagtgtacat ctgaggtcca agtcctctgt ggatatttgc tgcagatgaa accaatagcg
      781 actcctaagc ctgaatatcg tgaggtaggg gggataggaa ggaattagcg aaatcaaggt
      841 tctacaaaca gaatcgtgac ttgaagccat atatagcgga tgaggaactc taaaatccaa
      901 ataggtgtcg taacctatat acgtaaatta cgagagtaaa ctaggaaaga tgtacggctt
      961 attccgtgag cgtttaggac gtagtacaac gaatcatggg agtcagctga acacatagta
     1021 ttgaagaaat ttctgtaatg gaaatggagc gaagaagtga acaattaaat gaatacctct
     1081 ctaattaaat ttgtcaattc taattcctgg tatgaaaaga cagtgacctg aaaatgtaaa
     1141 cgatgggagc tgatcataaa tataggacgg tacatgcagt ggtgttagag attagtcctt
     1201 acttgatttg tgataacttc cccaaatttc ttctgctata cttttctcaa cttttaaaaa
     1261 tccaactaag aattttacct gggggtttgg gggcggagcc actaagttat cttatcgtta
     1321 gctgtcaaaa ctggtaggtt ttgataggct ggcgatatga tttttgggat attgtggaca
     1381 caatatctga gctcgcaaag accgaacaag gagagactga ggtctttagg aatcgtactg
     1441 acaatgtgag gcagccttac attgtcagac aagtataatg ttgaaagaat ggtaagatgg
     1501 gacaagaaat taagttaatc cgtaagcaat ttagaatcac gagacaagaa gaaaaacaga
     1561 taaaagaaat gatgagggaa caaaaagtgg atagtttctc agaatttctt cgtcaaaatt
     1621 tattgaaaaa gaattatcag gatagaattt ttgaaagttg gttctccctt tggcagtctc
     1681 aaaagtttga acagattagt cgagatgtgt atgaagttct ggttgtcgca agagaaaatc
     1741 atcaagtgac tcaagagcac gtctcaatct tattgacttg cgttcaagaa ttgattgcag
     1801 aagtgaatca agtacagcca ctcagtcgtg agtttcgtga aaaatatatg ggttaggagg
     1861 atgtaatggt ttatcgctat cgtaccaatc tcaaaaaagt atttctaact gatccagaat
     1921 tacaccaatt gaatgaacgg attgctaaga gcaattgtca aaatttttca gtctatgcca
     1981 gaaaagtttt gcttaatccc aatatgtcat ttgtcacgat taacactgat acttatgacc
     2041 agttagtttt tgaattgaga cgtattggaa ataacatcaa tcaaattgcg cgtgcgatta
     2101 atcaaagcca tctgatttct caggaccaat tacaagaatt gagtaaagga gtcggagagt
     2161 taattaagga agtggacaaa gaatttcaag tgtaggtgaa aagactgaag gagtttcatg
     2221 gtagttacta aacactttgc gacgcacgga aaaaaatatc gtaggcgttt gattaaatat
     2281 atcctcaatc cagataaaac agataatcta aaattagtat ctgattttgg catgagtaat
     2341 tacttagatt ttcctagcca tacagaaatg gtagaaatgt acaatgttaa ctttactaat
     2401 aacgacaagt tgtacgagtc cagaaatgac cgacaagaaa aacaccaaca aactattcat
     2461 gcccatcatc tcatccaatc attttctcct gaagataatc tgacacctga agaaattaac
     2521 cgcattggtt atgagaccat gatggaattg acaggaggtc gttttaagtt tatcgtagca
     2581 actcacacag acaaagatca tgttcataat cacatcctaa tcaacgctat tgaccgcaat
     2641 tcagataaaa agttgatatg gaactatgcc ttggaacgaa acctccgtat gatttcagac
     2701 cgtatttcta aaatggctgg tgcaaaaatt attgagaaac gttattctta tcgaggttat
     2761 aaaaaatata gggaatctag tcataaattt gaattgaaac aacgtcttta ttttttgatg
     2821 cagcaatcta aatagtttga tgatttttta gagaaagcaa agcagttgca tgttcagatt
     2881 gattttagtc aaaagcatag tcgattcatg atgacggatc gagcaatgac aaaacctatt
     2941 cgaggacgcc aactcagcaa acgagatcta tatgatgaag aattttttag aacgcatttt
     3001 gctaagcaag agattgaaag tcgtttagaa tttttgttga accgtgtcaa ttctttagaa
     3061 gagttaataa caaaagcaaa agaattgaat ctaaccattg acttaaaaca aaaaaatgta
     3121 acttttatcc tgaaagaaaa taatcaaaag ataagtttgg gtcatcaaaa aataagtgat
     3181 aagaaattat atgatgtcaa attttttcaa gattatttta aaaataagga agtcattgct
     3241 tcagaaggat tagagaattt acaggaacag taccatgctt tccaagaaga acgagataag
     3301 gataaagtat ccactgaaga gattgaggaa gcctttaaga catttaagaa gcctttaaga
     3361 catttaagga aaaatgagat accgttcgtg aatttgaagt ggaacttgca gagaaccaaa
     3421 tagagaagct agttgataag ggcgtctata tcaaggtgtc tttcggtgtc aaatagagcg
     3481 gtcttatttt cattcccaac tatcaattgg atattatgga agaagaaaat cataaaaaat
     3541 ataaagtcta cattcgagaa acgtcttctt actttgtcta taataaagaa aacatggata
     3601 ataattgttt catcaagggt aggaccttaa tcagacaatt gagcaacgat agccaaaaac
     3661 tcccctatag acgaccaact ttaaaaagtc ttcaagagaa gatttctgaa attaatctta
     3721 tgattgaact atctaacacg aacaaacaat accaagaaat caaagatgag cttgtattag
     3781 aaattgcaga gattgatatg aagctagaag aaacccaaga aaaaatcgcc accttaaaca
     3841 agatggcgga agtccttatc aatttgaaga gtgaagatga gatcggtaga aaattagcta
     3901 agtatgattt tgaccaaatg aacatgacgg aatcaataat gttagatcga ctcaatacat
     3961 atattttaaa attacaacag gaac
//
LOCUS       DAVLBE010000093         3929 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.093, whole genome shotgun sequence.
ACCESSION   DAVLBE010000093 DAVLBE010000000
VERSION     DAVLBE010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3929)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3929)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3929
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.093"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            153..380
                     /locus_tag="VXB91_001954"
     CDS             153..380
                     /locus_tag="VXB91_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0471344.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
     gene            668..3565
                     /gene="nanA"
                     /locus_tag="VXB91_001955"
     CDS             668..3565
                     /gene="nanA"
                     /locus_tag="VXB91_001955"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored neuraminidase NanA"
                     /protein_id="HEV0471345.1"
                     /translation="MNRSVQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGESSTLTDTEKSQPSSETELSGNNQEQERKDKQEEKIPRDYYARDLEN
                     VETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFKPDAKAPAFYNLFSVSS
                     ATKKDEYFTMAVYNNTATLEGRGSDGKQFYNNYNDAPLKVKPGQWNSVTFTVEKPTAE
                     LPKGRVRLYVNGVLSRTSLRSGNFIKDMPDVTHVQIGATKRANNTVWGSNLQIRNLTV
                     YNRALTPEEVQKRSQLFKRSDLEKKLPEGAALTEKTDIFESGRNGNPNKDGIKSYRIP
                     ALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGDRVTITNLRDNPKASD
                     PSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKKIDGKTYQILY
                     REGEKGAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGNQLLGNIYFTTN
                     KTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPH
                     KGRILIPVYTTNNVSHLNGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMN
                     NKRAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQ
                     MSAIHTMHEGKEYIILSNAGGPKRENGMVHLARVEENGELTWLKHNPIQKGEFAYNSL
                     QELGNGEYGILYEHTEKGQNAYTLSFRKFNWDFLSKDLISPTEAKVKRTREMGKGEMG
                     KGVIGLEFDSEVLVNKDPTLQLANGKTATFLTQYDSKTLLFAVDKEDIGQEIIGIAKG
                     SIESMHNLPVNLAGARVPGGVNGSKAAVHEVPEFTGGVNGTEPAVHEIAEYKGSDSLV
                     TLTTKEDYTYKAPLAQQALPETGNKESDLLASLGLTAFFLGLFTLGKKREQ"
BASE COUNT         1342 a          654 c          870 g         1063 t
ORIGIN      
        1 aaaaatgagg tataataaat ttactaacgc ttataaaaag tgatagaatc tatttttatg
       61 tatatttaaa gatagattgc tgtaaaaata gtagtagcta tgcgaaataa cagatagaga
      121 gaagggattg aagcttagaa aaggggaata atatgatatt taaggcattc aagacaaaaa
      181 agcagagaaa aagacaagtt gaactacttt tgacagtttt tttcgacagt tttctgattg
      241 atttatttct tcacttattt gggattgtcc cctttaagct ggataagatt ctgattgtga
      301 gcttgattat atttcccatt atttctacaa gtatttatgc ttatgaaaag ctatttgaaa
      361 aagtgttcga taaggattga gcaggaagta tggtgtaaat agcataggct gatgtccatc
      421 atttgcttat aaagagatat tttagtttaa ttgcagcggt gtcctggtag ataaactaga
      481 ttggcaggag tctgattgga gaaaggagag gggaaaattg gcaccaattt gagatagttt
      541 gtttagttca tttttgtcat ttaaatgaac tgtagtaaaa gaaagttaat aaaagacaaa
      601 ctaagtgcat tttctggagt aaatgtctta tttcagaaat cgggatatag atatagagag
      661 gatcagtatg aatcggagtg ttcaagaacg taagtgtcgt tatagcatta ggaaactatc
      721 ggtaggagcg gtttctatga ttgtaggagc agtggtattt ggaacgtctc ctgttttagc
      781 tcaagaaggg gcaagtgagc aacctctggc aaatgaaact caactttcgg gggagagctc
      841 aaccctaact gatacagaaa agagccagcc ttcttcagag actgaacttt ctggcaataa
      901 tcaagaacaa gaaaggaaag ataagcaaga agaaaaaatt ccaagagatt actatgcacg
      961 agatttggaa aatgtcgaaa cagtgataga aaaagaagat gttgaaacca atgcttcaaa
     1021 tggtcagaga gttgatttat caagtgaact agataaacta aagaaacttg aaaacgcaac
     1081 agttcacatg gagtttaagc cagatgccaa ggccccagca ttctataatc tcttttctgt
     1141 gtcaagtgct actaaaaaag atgagtactt cactatggca gtttacaata atactgctac
     1201 tctagagggg cgtggttcgg atgggaaaca gttttacaat aattacaacg atgcaccctt
     1261 aaaagttaaa ccaggtcagt ggaattctgt gactttcaca gttgaaaaac cgacagcaga
     1321 actacctaaa ggccgagtgc gcctctacgt aaacggggta ttatctcgaa caagtctgag
     1381 atctggcaat ttcattaaag atatgccaga tgtaacgcat gtgcaaatcg gagcaaccaa
     1441 gcgtgccaac aatacggttt gggggtcaaa tctacagatt cggaatctca ctgtgtataa
     1501 tcgtgcttta acaccagaag aggtacaaaa acgtagtcaa ctttttaaac gctcagattt
     1561 agaaaaaaaa ctacctgaag gagcggcttt aacagagaaa acggacatat tcgaaagcgg
     1621 gcgtaacggt aacccaaata aagatggaat caagagttat cgtattccag cacttctcaa
     1681 gacagataaa ggaactttga tcgcaggtgc agatgaacgc cgtctccatt cgagtgactg
     1741 gggtgatatc ggtatggtca tcagacgtag tgaagataat ggtaaaactt ggggtgaccg
     1801 agtaaccatt accaacttac gtgacaatcc aaaagcttct gacccatcga tcggttcacc
     1861 agtgaatatc gatatggtgt tggttcaaga tcctgaaacc aaacgaatct tttctatcta
     1921 tgacatgttc ccagaaggga agggaatctt tggaatgtct tcacaaaaag aagaagccta
     1981 caaaaaaatc gatggaaaaa cctatcaaat cctctaccgt gaaggagaaa agggagctta
     2041 taccattcga gaaaatggta ctgtctatac accagatggt aaggcgacag actatcgcgt
     2101 tgttgtagat cctgttaaac cagcctatag cgacaagggt gatctataca agggtaacca
     2161 attactaggc aatatctact tcacaacaaa caaaacttct ccatttagaa ttgccaagga
     2221 tagctatcta tggatgtcct acagtgatga cgacgggaag acatggtcag cgcctcaaga
     2281 tattactccg atggtcaaag ccgattggat gaaattcttg ggtgtaggtc ctggaacagg
     2341 aattgtactt cggaatgggc ctcacaaggg acggattttg ataccggttt atacgactaa
     2401 taatgtatct cacttaaatg gctcgcaatc ttctcgtgtc atctattcag atgatcatgg
     2461 aaaaacttgg catgctggag aagcggtcaa cgataaccgt caggtagacg gtcaaaagat
     2521 ccactcttct acgatgaaca ataaacgtgc gcaaaataca gaatcaacgg tggtacaact
     2581 aaacaatgga gatgttaaac tctttatgcg tggtttgact ggagatcttc aggttgctac
     2641 aagtaaagac ggaggagtga cttgggagaa ggatatcaaa cgttatccac aggttaaaga
     2701 tgtctatgtt caaatgtctg ctatccatac gatgcacgaa ggaaaagaat acatcatcct
     2761 cagtaatgca ggtggaccga aacgtgaaaa tgggatggtc cacttggcac gtgtcgaaga
     2821 aaatggtgag ttgacttggc tcaaacacaa tccaattcaa aaaggagagt ttgcctataa
     2881 ttcgctccaa gaattaggaa atggggagta tggcatcttg tatgaacata ctgaaaaagg
     2941 acaaaatgcc tataccctat catttagaaa atttaattgg gactttttga gcaaagatct
     3001 gatttctcct accgaagcga aagtgaagcg aactagagag atgggcaaag gagagatggg
     3061 caaaggagtt attggcttgg agttcgactc agaagtattg gtcaacaagg atccaaccct
     3121 tcaattggca aatggtaaaa cagcgacttt cctaacccag tatgatagca agaccttgtt
     3181 atttgcagta gataaggaag atatcggaca ggaaattatt ggtatagcta aaggaagcat
     3241 cgaaagtatg cataatcttc ctgtaaatct agcaggtgcc agagttcctg gcggagtaaa
     3301 tggtagcaaa gcagcggtgc atgaagttcc agaatttaca gggggagtta atggtacaga
     3361 gccagctgtt catgaaatcg cagagtataa gggatctgat tcgcttgtaa ctcttactac
     3421 aaaagaagat tatacttaca aagctcctct tgctcagcag gcacttcctg aaacaggaaa
     3481 caaggagagt gacctcctag cttcactagg actaacagct ttcttccttg gtctgtttac
     3541 gctagggaaa aagagagaac aataagagaa gaattctaaa catttgattt tgtaaaaata
     3601 gaaggagata gcaggttttc aagcctgcta tctttttttg atgacattca agctgatacg
     3661 aaatcataag aggtctgaaa ctactttcag ggtagtctgt tctataaaat atagtagatt
     3721 gaaataagat gtgaacaact ctaccaggaa agtcaaatta atttatagaa ttattttagc
     3781 agtcaaggtg tactgttata gattcaatat attatgcgac tattaacctt gtcttctcct
     3841 aaaattgact ttcttgtttt cttatcttgt ccactcgaaa caagtattgt aagaatttga
     3901 ttatttttga aagtactttt aatatattt
//
LOCUS       DAVLBE010000094         3879 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.094, whole genome shotgun sequence.
ACCESSION   DAVLBE010000094 DAVLBE010000000
VERSION     DAVLBE010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3879)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3879)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3879
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.094"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            <1..418
                     /locus_tag="VXB91_001956"
     CDS             <1..418
                     /locus_tag="VXB91_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HEV0471346.1"
                     /translation="KNKADQDSKPDEDKGHDEVSEPTHPESDEKENHAGLNPSADNLY
                     KPSTDTEETEEEAEDTTDEAEIPQVEHSVINAKIADAEALLEKVTDPSIRQNAMETLT
                     GLKSSLLLGTKDNNTISAEVDSLLALLKKSQPAPIQ"
     gene            628..3747
                     /gene="phtE"
                     /locus_tag="VXB91_001957"
     CDS             628..3747
                     /gene="phtE"
                     /locus_tag="VXB91_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtE"
                     /protein_id="HEV0471347.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQVSQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEKVNSNVAVARSQGRYTTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLAGKNMQPSQLSYSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELY
                     DSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPI
                     SGTGSTVSTNAKPNEVVSSLGSLSSNPSSLTTSKELSSASDGYIFNPKDIVEETATAY
                     IVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGTSHEKHEEDGYGFDANRII
                     AEDESGFVMSHGDHNHYFFKKDLTEEQIKAAQKHLEEVKTSHNGLDSLSSHEQDYPSN
                     AKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVG
                     IGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVS
                     FSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFK
                     YTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDAL
                     VRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYI
                     VEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLSETGNSTS
                     NSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTG
                     EAPQGNGENKPSENGKVSTGTVENQPTENKPADSLPEAPNEKPVKPENSTDNGMLNPE
                     GNVGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTIELRLPSGEVI
                     KKNLSDLIA"
BASE COUNT         1455 a          632 c          755 g         1037 t
ORIGIN      
        1 taaaaataag gcagaccaag acagtaaacc tgatgaagat aagggacatg atgaagtaag
       61 tgagccaact caccctgaat ctgatgaaaa agagaatcac gctggtttaa atccttcagc
      121 agataatctt tataaaccaa gcactgatac ggaagagaca gaggaagaag ctgaagatac
      181 tacagatgag gctgaaattc ctcaagtaga gcattctgtt attaacgcta agatagcaga
      241 tgcggaggcc ttgctagaaa aagtaacaga tcctagtatt agacaaaatg ctatggagac
      301 attgactggt ctaaaaagta gtcttcttct cggaacgaaa gataataaca ctatttcagc
      361 agaagtagat agtctcttgg ctttgttaaa aaaaagtcaa ccggctccta tacagtagta
      421 aaatgaatgg agcatatttt atggagaagt aacctttcgt gttacttctc ttttttagaa
      481 aaacgtaaca gaaacttgac aaaagtaatt ttaaatagta aactatttac tggttaatta
      541 aatggttaaa taaccggttt agaaaactat ttaataaagt aaaagaagtt gagaaaaaac
      601 ttcatcattt attgaaatga gggatttatg aaatttagta aaaaatatat agcagctgga
      661 tcagctgtta tcgtatcctt gagtctatgt gcctatgcac taaaccagca tcgttcgcag
      721 gaaaataagg acaataatcg tgtctcttat gtggatggca gccagtcaag tcagaaaagt
      781 gaaaacttga caccagacca ggttagccag aaagaaggaa ttcaggctga gcaaattgta
      841 atcaaaatta cagatcaggg ctatgtaacg tcacacggtg accactatca ttactataat
      901 gggaaagttc cttatgatgc cctctttagt gaagaactct tgatgaagga tccaaactat
      961 caacttaaag acgctgatat tgtcaatgaa gtcaagggtg gttatatcat caaggtcgat
     1021 ggaaaatatt atgtctacct gaaagatgca gctcatgctg ataatgttcg aactaaagat
     1081 gaaatcaatc gtcaaaaaca agaacatgtc aaagataatg agaaggttaa ctctaatgtt
     1141 gctgtagcaa ggtctcaggg acgatatacg acaaatgatg gttatgtctt taatccagct
     1201 gatattatcg aagatacggg taatgcttat atcgttcctc atggaggtca ctatcactac
     1261 attcccaaaa gcgatttatc tgctagtgaa ttagcagcag ctaaagcaca tctggctgga
     1321 aaaaatatgc aaccgagtca gttaagctat tcttcaacag ctagtgacaa taacacgcaa
     1381 tctgtagcaa aaggatcaac tagcaagcca gcaaataaat ctgaaaatct ccagagtctt
     1441 ttgaaggaac tctatgattc acctagcgcc caacgttaca gtgaatcaga tggcctggtc
     1501 tttgaccctg ctaagattat cagtcgtaca ccaaatggag ttgcgattcc gcatggcgac
     1561 cattaccact ttattcctta cagcaagctt tctgccttag aagaaaagat tgccagaatg
     1621 gtgcctatca gtggaactgg ttctacagtt tctacaaatg caaaacctaa tgaagtagtg
     1681 tctagtctag gcagtctttc aagcaatcct tcttctttaa cgacaagtaa ggagctctct
     1741 tcagcatctg atggttatat ttttaatcca aaagatatcg ttgaagaaac ggctacagct
     1801 tatattgtaa gacatggtga tcatttccat tacattccaa aatcaaatca aattgggcaa
     1861 ccgactcttc caaacaatag tctagcaaca ccttctccat ctcttccaat caatccagga
     1921 acttcacatg agaaacatga agaagatgga tacggatttg atgctaatcg tattatcgct
     1981 gaagatgaat caggttttgt catgagtcac ggagaccaca atcattattt cttcaagaag
     2041 gacttgacag aagagcaaat taaggctgcg caaaaacatt tagaggaagt taaaactagt
     2101 cataatggat tagattcttt gtcatctcat gaacaggatt atccaagtaa tgccaaagaa
     2161 atgaaagatt tagataaaaa aatcgaagaa aaaattgctg gcattatgaa acaatatggt
     2221 gtcaaacgtg aaagtattgt cgtgaataaa gaaaaaaatg cgattattta tccgcatgga
     2281 gatcaccatc atgcagatcc gattgatgaa cataaaccgg ttggaattgg tcattctcac
     2341 agtaactatg aactgtttaa acccgaagaa ggagttgcta aaaaagaagg gaataaagtt
     2401 tatactggag aagaattaac gaatgttgtt aatttgttaa aaaatagtac gtttaataat
     2461 caaaacttta ctctagccaa tggtcaaaaa cgcgtttctt ttagttttcc gcctgaattg
     2521 gagaaaaaat taggtatcaa tatgctagta aaattaataa caccagatgg aaaagtattg
     2581 gagaaagtat ctggtaaagt atttggagaa ggagtaggga atattgcaaa ctttgaatta
     2641 gatcaacctt atttaccagg acaaacattt aagtatacta tcgcttcaaa agattatcca
     2701 gaagtaagtt atgatggtac atttacagtt ccaacctctt tagcttacaa aatggccagt
     2761 caaacgattt tctatccttt ccatgcaggg gatacttatt taagagtgaa ccctcaattt
     2821 gcagtgccta aaggaactga tgctttagtc agagtgtttg atgaatttca tggaaatgct
     2881 tatttagaaa ataactataa agttggtgaa atcaaattac cgattccgaa attaaaccaa
     2941 ggaacaacca gaacggccgg aaataaaatt cctgtaacct tcatggcaaa tgcttatttg
     3001 gacaatcaat cgacttatat tgtggaagta cctatcttgg aaaaagaaaa tcaaactgat
     3061 aaaccaagta ttctaccaca atttaaaagg aataaagcac aagaaaactc aaaacttgat
     3121 gaaaaggtag aagaaccaaa gactagtgag aaggtagaaa aagaaaaact ttctgaaact
     3181 gggaatagta ctagtaattc aacgttagaa gaagttccta cagtggatcc tgtacaagaa
     3241 aaagtagcaa aatttgctga aagttatggg atgaagctag aaaatgtctt gtttaatatg
     3301 gacggaacaa ttgaattata tttaccatcg ggagaagtca ttaaaaagaa tatggcagat
     3361 tttacaggag aagcacctca aggaaatggt gaaaataaac catctgaaaa tggaaaagta
     3421 tctactggaa cagttgagaa ccaaccaaca gaaaataaac cagcagattc tttaccagag
     3481 gcaccaaacg aaaaacctgt aaaaccagaa aactcaacgg ataatggaat gttgaatcca
     3541 gaagggaatg tggggagtga ccctatgtta gatccagcat tagaggaagc tccagcagta
     3601 gatcctgtac aagaaaaatt agaaaaattt acagctagtt acggattagg cttagatagt
     3661 gttatattca atatggatgg aacgattgaa ttaagattgc caagtggaga agtgataaaa
     3721 aagaatttat ctgatctcat agcgtaagga atagcagtag aaaaagtctg aatcaaaaat
     3781 gaagttctct caaaagttag aaataaaact ctgactttgg gagaatttca ttttattatt
     3841 aatatataaa atttcttgac atacaactta aaaagaggt
//
LOCUS       DAVLBE010000095         3795 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.095, whole genome shotgun sequence.
ACCESSION   DAVLBE010000095 DAVLBE010000000
VERSION     DAVLBE010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3795)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3795)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3795
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.095"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            20..>3795
                     /locus_tag="VXB91_001958"
     CDS             20..>3795
                     /locus_tag="VXB91_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEV0471348.1"
                     /translation="MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQE
                     TAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSK
                     NERQALVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGMGNGVLVSVHALENHLLL
                     NYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDY
                     NVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQL
                     AEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYRDETIETKIDFQEEI
                     QENPDLAEGTVRVKQEGALGKKVEIVRIFSVNNEEVSREIISTSTTAPVSRIVEKGTK
                     KAQVIKEQAETGAEHKEVQSGAIVEPAIQPELPAAVLTDKGESAVQPELPEAVVSDKG
                     VPEVQPALPEAVMTDKGDPEQVEPLPEYTGVQAGAIVEPEKVEPEYAGVQAGAIVEPE
                     QVAPLPEYTGVQAGAIVEPEKVEPSKEYTGVQAGAIVEPEQIAPLPEYTGVQAGAIVE
                     PEKVEALKEYTGKIEQPSAEDTKPNNENTNTPEEMSIQKKSSALINMNFITDSSKVTG
                     VGSATFIAPNVLLTVAHNFINNSTDNTTGEFRGDKSKNVYEWVTPDGQKGTFTANNIH
                     FYNKKDYPKGFIYDLAVIKLPETTGREHVELVKNYSKVNLNDKLNVHGYPARKYTHLK
                     DATVEMEQEYANNTYGVQYQGGNPGMSGGGIFNANGEVIGVHQNGAQNRSGGLILSPT
                     QLAWIKSIIAGNEIPPVYDELYRHKDEKKDDAKDEKEVIKKLELRNISSVELYSKDGN
                     KYRHVTSLASLPSNAENYFMKVKSENFKDVMLPVTSITNDTKDNRDVYKIVASANSLI
                     QHENNNVLENYTYYLPKTQQSETGVYTSFKNLVDAMNSNPNGTFRLGATMDAREVELP
                     DGQESYVNNVFHGILVGTNNEKYYAIYNLKKPLFGELNGATVEKLSLKDVNISAKDDT
                     ATLAKEANNNTHIDNVHADGAIAGERSIGGLVSQVNNSTISNSSYTGRITNTYKTVAS
                     YQIGGLVGKLSGPRGLIDKSFASIDLSSNATQGDQSIGGIVGAVENSALISNSYAEGN
                     LNNVQRFANVGGVVGNLWDPVGGLEKSGRLSNVLSDVNVTNGNAIAGYNFNGIKANGT
                     YSNKNNKVVNVVQEDDEILTKDSTVQRGEVLEDAQIKEKKATFVSKNTIKTEDF"
BASE COUNT         1447 a          565 c          768 g         1015 t
ORIGIN      
        1 tttatttcaa ggaggaataa tggaaaagta ttttggtgaa aaacaagagc gtttttcatt
       61 tagaaaatta tcagtaggac ttgtatctgc aacgatttca agtttatttt ttatgtctgt
      121 attagctagt tcatctgtgg atgctcaaga aactgcggga gttcactata aatatgtggc
      181 agattcagag ctatcatcag aagaaaagaa gcagcttgtc tatgatattc cgacatacgt
      241 ggagaatgat gatgaaactt attatcttgt ttataagtta aattctcaaa atcaactggc
      301 ggaattacca aatactggaa gcaagaatga gaggcaagcc ctagttgctg gtgctagctt
      361 agctgctctg ggaattttaa tttttgctgt ttccaagaaa aaggttaaga ataaaacggt
      421 attacattta gtattggttg cgggaatggg aaatggtgtc ttagtttcag tccatgcttt
      481 agaaaatcat cttttgctaa attacaatac ggactatgaa ttgacctctg gagaaaaatt
      541 acctcttcct aaagagattt caggttacac ttatattgga tatatcaaag agggaaaaac
      601 gacttctgat tttgaagtaa gtaatcaaga aaaatcagca gccactccta caaaacaaca
      661 aaaggtggat tataatgtta caccaaattt tgtagaccat ccatcaacag tacaagctat
      721 tcaggaacaa acacctgttt cttcaactaa gccgacagaa gttcaagtag ttgaaaaacc
      781 tttctctact gaattaatca atccaagaaa agaagagaaa caatcttcag attctcaaga
      841 acaattagcc gaacataaga atctagaaac gaagaaagag gagaagattt ctccaaagga
      901 aaagactggg gtaaatacat taaatccaca ggatgaagtg ctatcaggtc agttgaacaa
      961 accggaactc ttatatcgtg acgaaactat agaaacaaaa atagattttc aagaagaaat
     1021 tcaagaaaat cctgatttag cagaaggaac tgtaagagta aaacaagaag gtgcattagg
     1081 taagaaagtt gaaatcgtca gaatattttc tgtaaacaat gaagaagttt cacgagaaat
     1141 tatttcaact tcaacgactg cgcctgtttc aagaatagtc gaaaaaggta ctaaaaaagc
     1201 tcaagttata aaggaacaag ctgagactgg tgcagaacat aaggaagtac agtctggagc
     1261 tattgttgaa cccgcaattc agcctgaact accagcagct gtattaaccg acaaaggtga
     1321 gtcagcagtc caaccagagt tgccagaagc tgtagtaagt gataaaggcg taccagaagt
     1381 tcaaccagcg ttaccagagg cagtcatgac tgacaagggt gatccagagc aggtagaacc
     1441 gctaccagaa tatacaggag tacaagctgg agctattgtt gaacctgaaa aagttgaacc
     1501 ggaatatgct ggagtacaag ctggcgctat tgttgaacca gagcaggtag caccactacc
     1561 agaatacaca ggggtgcaag ccggagcaat agtagaacca gaaaaagtag aaccatcaaa
     1621 agaatacaca ggggtgcagg ctggcgctat tgttgaacca gagcagatag caccactacc
     1681 agaatacaca ggggtgcaag ccggagcgat agtcgagcca gagaaagtag aagcactgaa
     1741 agaatatact ggtaaaatcg aacaacctag tgcagaagat actaaaccaa ataatgaaaa
     1801 tactaataca ccagaagaaa tgagtattca gaaaaaatct agtgcattaa ttaatatgaa
     1861 ctttattaca gattcgtcga aggttactgg agtaggatca gctactttta ttgcaccaaa
     1921 tgtactttta acagtagcac ataatttcat taataattct actgataata ctactggcga
     1981 atttagaggt gataaatcta aaaacgtata tgagtgggtg actcctgatg gacaaaaagg
     2041 aacatttact gctaacaata ttcattttta taataaaaaa gattatccaa aaggatttat
     2101 ctatgattta gcagtgatta agctacctga aacaactggc agagaacatg tagaattagt
     2161 taaaaattat tcgaaagtaa atcttaatga caaactaaat gttcatggat atccagctag
     2221 gaaatatacg cacttaaaag atgctacggt agaaatggaa caagaatatg cgaataacac
     2281 ctacggtgtt caatatcaag gtggaaatcc tggtatgagt ggtggaggaa tatttaatgc
     2341 taatggtgaa gttattggtg tgcatcaaaa tggagcacaa aatcgctcag gcggattgat
     2401 tttatctcct acacaattag cttggattaa gagtattata gcaggtaatg aaattccacc
     2461 agtatacgat gaactttatc gtcataaaga tgagaaaaaa gatgacgcta aagatgaaaa
     2521 agaagttatt aagaaattag aacttagaaa tatatcttct gtagaactat attcaaaaga
     2581 tggtaataag tatcgacatg taacttcact tgcttcttta ccaagtaatg cagaaaatta
     2641 ctttatgaaa gttaaatcag agaactttaa agatgtgatg ctaccagtta caagcattac
     2701 taatgatact aaagataata gagatgttta taagatagta gcaagtgcaa atagtctgat
     2761 acaacatgaa aataataatg tactagaaaa ttatacatac tatttaccaa aaactcagca
     2821 aagtgaaact ggggtatata catcatttaa aaatttagta gatgcaatga atagcaatcc
     2881 taatggcaca ttccgtttag gagcaactat ggatgctcgt gaagttgaac ttccagatgg
     2941 tcaagaaagt tatgtgaata atgtattcca tggaatatta gtaggaacaa ataatgagaa
     3001 atattatgct atttataatt tgaaaaaacc attatttggg gaattaaatg gtgctacagt
     3061 agaaaaactt tcactaaaag atgttaatat ttccgcaaag gacgatactg caacacttgc
     3121 gaaagaagca aataacaata ctcatattga taacgttcat gctgatggag cgatagctgg
     3181 ggaacgtagc ataggaggat tagtatcaca agttaataat tctactattt ctaacagtag
     3241 ctatacaggt agaataacta atacatataa aacagttgct agttatcaaa tcggaggttt
     3301 agtaggcaaa ctttctggtc cgaggggatt aatagataag tcgttcgcat caatcgattt
     3361 atcttcaaat gcaacacaag gagaccagtc tattggtgga atagttggtg cagtagaaaa
     3421 tagtgcgctt attagtaata gttatgctga aggaaatcta aataatgttc aacgttttgc
     3481 aaacgttggt ggagtagttg gtaatctttg ggatccggtt ggaggattag aaaaatccgg
     3541 tcgactttct aatgtactaa gcgatgttaa tgtaacgaat ggtaatgcta ttgcaggtta
     3601 taattttaat ggtataaaag caaatggcac atacagtaat aaaaataata aggttgtgaa
     3661 cgtagtacaa gaagatgatg aaatcttaac taaggattct actgttcaaa gaggagaagt
     3721 attagaagat gcacaaataa aagagaaaaa agctactttt gtatctaaaa atactattaa
     3781 aacagaagat tttaa
//
LOCUS       DAVLBE010000096         3396 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.096, whole genome shotgun sequence.
ACCESSION   DAVLBE010000096 DAVLBE010000000
VERSION     DAVLBE010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3396)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3396)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3396
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.096"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            147..1349
                     /locus_tag="VXB91_001959"
     CDS             147..1349
                     /locus_tag="VXB91_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEV0471349.1"
                     /translation="MKILFVNMFYNEAGGAQKSTKFLAEQLVKEGHEVFAYSDDAIDS
                     DIDEVINRVKIFRRRTPLFSLHYIFSAKKNPAKHFFYKIFETYNVFAKRKFINIIEEV
                     QPDIVHFNTISGMSLSIVKEAKKRNIRTVWTLRDYWLEYPWGEKDISLIKLLNRIYRP
                     FVKKSLRHLDIVTAPSAFTLNNFINKGFINPSSQKCMVIENAVIFSKGKLENIIKQKQ
                     ETKRNPEKTNFLFVGSILEIKGVFNLVKAFKKLTSPEISLKIVGKGKDLEKLQKEIES
                     DPRIQYLGFQDTETLYKTYQNSDVLVVPSAWDEPFGRVVIEGNANGLPVITSDRGGLP
                     EIVQTVGGGEIFTDESGNTLYSLLKKFVEMENYNVYYQCILENIDIYSIEKQSEKFTN
                     LYLDKEIE"
     gene            1383..2615
                     /locus_tag="VXB91_001960"
     CDS             1383..2615
                     /locus_tag="VXB91_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HEV0471350.1"
                     /translation="MKIAVAGTGYVGLSIAVLLAQHHEIKAVDIVAEKVELINQKKSP
                     IQDDYIEKYLVEKDLNLEATMDAKYAYEDAEFVVVAAPTNYDSKKNFFDTSAVEAVIQ
                     QVKKINPKAVIIIKSTIPVGFTESVQKKYQYKNILFSPEFLRESKALYDNLYPSRIIV
                     GTDLEDTYLKDKANIFASLLKEGAIKEDIDTLFMGVTEAEAVKLFANTYLALRVSYFN
                     ELDTYAEVKGLDAKAIIDGIGLDPRIGNHYNNPSFGYGGYCLPKDSKQLLANYFDVPQ
                     NMMTATVESNRTRKDFIAQRILEKAGVSETDSLDAFKNIQDIVIGIYRLTMKSNSDNF
                     RHSSIQGVMKRLKAKGVTVIIYEPTLKDGETFFGNKVVNNLDKFKEASNVIVANRFEP
                     SLEDVSNKVYSRDIFKRD"
     gene            2834..3396
                     /locus_tag="VXB91_001961"
                     /pseudo
     CDS             2834..3396
                     /locus_tag="VXB91_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         1215 a          472 c          647 g         1062 t
ORIGIN      
        1 tgtttatctc ggattttgta aacgacctta ttttacattt atcagttcag tttgttattt
       61 tatttttaat atggggaatt gggatgtata ttagcggaga gtatcgacga gtcttcgcgg
      121 ttataagaaa ataaaggagc aattttgtga aaattttatt tgtgaatatg ttttataatg
      181 aagcaggagg tgcacaaaag agcaccaaat ttctagctga acaacttgta aaagaaggac
      241 atgaggtatt tgcatactct gatgatgcca ttgattcaga tattgatgaa gttattaata
      301 gggttaagat ttttagaaga agaaccccgc tttttagtct tcactatatt ttcagtgcta
      361 agaagaatcc agctaaacat tttttctata aaatatttga aacctataat gtatttgcga
      421 aaagaaaatt tatcaatatc attgaggaag tacaaccaga tattgttcac tttaatacaa
      481 tttcaggaat gtctttatca atagttaaag aagctaaaaa gagaaatatc aggaccgttt
      541 ggaccttgcg agactattgg ctagaatatc catggggtga gaaagatatt tctcttatca
      601 aacttctaaa tagaatatat agaccttttg ttaagaaaag tttaagacac ttagacatag
      661 taacagcacc atcagcattt actttgaata attttatcaa taaaggattt attaacccat
      721 cttctcaaaa atgtatggtc attgaaaatg ctgttatatt ttcaaagggt aagttggaaa
      781 atattatcaa acaaaagcaa gaaacaaaaa gaaatccaga aaaaacgaat tttctttttg
      841 taggttctat acttgaaata aagggcgttt ttaacttagt aaaggccttt aaaaaactaa
      901 ctagtccgga aatttctttg aaaattgtag gaaaaggaaa agatttagaa aaacttcaaa
      961 aagaaattga gagtgatcct agaatacaat atttaggctt tcaagataca gaaaccctct
     1021 ataaaactta tcaaaattcg gatgtattgg tcgtcccatc tgcttgggat gaaccgtttg
     1081 gtagagttgt aattgaagga aatgcaaatg gccttcctgt catcacttca gatagaggtg
     1141 gattacctga aattgtgcaa acagtaggag gaggagaaat ttttacagat gaatcgggaa
     1201 atacattata tagtctttta aagaaatttg tagaaatgga aaactacaat gtctattacc
     1261 aatgcattct tgagaatatt gatatttatt ctatcgaaaa acaaagtgaa aagttcacta
     1321 atctgtattt agataaagaa atcgaataat aagttgtttt tgtagcagta acggaggtaa
     1381 ttatgaaaat agcggtagca ggaacaggtt atgtaggatt atcaattgct gtgttgttgg
     1441 cacaacatca cgaaataaaa gcagttgata ttgttgctga aaaagttgaa ttaatcaatc
     1501 aaaaaaagtc tccaattcag gatgattata ttgaaaaata tttagtggaa aaagatttaa
     1561 atttggaagc aactatggat gctaagtatg cttatgaaga tgcagaattt gttgttgttg
     1621 cagcaccaac aaattatgat tcgaaaaaga acttttttga tacatcagca gtagaggcgg
     1681 tcattcaaca agtaaaaaaa attaatccca aagcggtaat aattattaaa tctacaatcc
     1741 ctgttggatt cacagagtcc gttcaaaaga aatatcagta taaaaatatc ttatttagtc
     1801 cagaattttt acgcgaatct aaagcattat acgataacct gtatccaagt cgcatcattg
     1861 ttggaactga cttagaagat acttatttaa aagacaaagc taatatattt gcttccctac
     1921 taaaagaggg ggctattaaa gaagacatag atacactttt catgggagta acggaagctg
     1981 aggcagttaa attatttgcc aatacctacc ttgcgttgcg tgtttcttac tttaatgaat
     2041 tggatactta tgcagaggtg aaaggtttgg atgcaaaagc cattattgat ggtattggcc
     2101 tagatccacg tataggaaat cattataaca atccatcctt tggctacggt gggtattgtt
     2161 tacctaaaga tagtaagcag ttattagcaa attactttga tgtaccacaa aatatgatga
     2221 cagcaactgt tgaaagcaat cgaacgcgta aggattttat cgctcaacgg attttagaaa
     2281 aagctggagt atctgagact gatagtttag atgcgtttaa gaacatacaa gatattgtta
     2341 taggtattta tcgtttaaca atgaaaagta attcggataa cttccgtcac tcctctattc
     2401 aaggcgttat gaaacgattg aaagctaagg gagttacggt tatcatctat gagccaactt
     2461 tgaaggacgg ggaaacattc tttggtaata aagtggtaaa taatctagat aaatttaaag
     2521 aagctagtaa tgttattgta gccaatcgtt ttgaaccttc actagaggat gtgtctaata
     2581 aagtttatag tcgagatata tttaagcgtg actaataaat acgtccacgt gacgtaatat
     2641 ctattaaatg aataaaatat taataaacat ggcatcgata tcttttttgg acttgaattg
     2701 tcaaattaag tgcacatttt tttcatagaa aacttcataa ggtgttttcc ggttaagaca
     2761 ttttcgtggt ctattatcta agttggttta tataatagac ttcctgcgaa acaaaatatg
     2821 gtataatagt tctatgaatt atgaagcaag taaacaacta accgatgtac gatttaagcg
     2881 tcttgttggt gttcaacgca cgacttttga agagatgtta gctgtattaa aaacagctta
     2941 tcaacttaaa cacgcaaaag gtggacgaaa acctaaatta agcctagaag actttcttat
     3001 ggcgactctt caataagtgc gagaataccg cacttatgaa caaattgcgg ctgattttgg
     3061 tattcacgaa agcaacttaa tccgtcggag ctaatgggtt gaagtaactc ttgttcaaag
     3121 gtggtgttac gatttcaaga actcctctca gttctgagga cacggtaatg attgatgcga
     3181 cggaagtaaa aatcaatcgc cctaaaaaaa gaattagcga attattctgg taaaaagaaa
     3241 tttcacgcta tgaagactca agcgattgtc acaagtcaag ggagaattgt ttctttggat
     3301 atcactgtga actattgtca tgatatgaag ttgttcaaaa tgagtcgcag aaatatcgga
     3361 caagctggta aaatcttggc tgacagtggt tatcaa
//
LOCUS       DAVLBE010000097         3374 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.097, whole genome shotgun sequence.
ACCESSION   DAVLBE010000097 DAVLBE010000000
VERSION     DAVLBE010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3374)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3374)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3374
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.097"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            <1..165
                     /locus_tag="VXB91_001962"
     CDS             <1..165
                     /locus_tag="VXB91_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEV0471351.1"
                     /translation="VSFAISSKGEKMKVENISYRVDHRILFDNISFDTSSSGVTLITG
                     KNGTGKSTLL"
     gene            complement(531..1841)
                     /locus_tag="VXB91_001963"
     CDS             complement(531..1841)
                     /locus_tag="VXB91_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HEV0471352.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNVATTNGTLDVLAQHILYRTRTHPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGRTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYQKTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTTIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            2078..2950
                     /locus_tag="VXB91_001964"
     CDS             2078..2950
                     /locus_tag="VXB91_001964"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HEV0471353.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAIMLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
     gene            3081..>3374
                     /locus_tag="VXB91_001965"
     CDS             3081..>3374
                     /locus_tag="VXB91_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HEV0471354.1"
                     /translation="MAYSIDFRKKVLSYCERTGSITEASHVFQISRNTIYGWLKLKEK
                     TGELNHQVKGTKPRKVDRDRLKNYLTDNPDAYLTEIASEFGCHPTTIHYALKAM"
BASE COUNT         1052 a          574 c          752 g          996 t
ORIGIN      
        1 gtttcttttg ctattagttc aaaaggagaa aaaatgaaag tagaaaatat ttcgtatagg
       61 gtggatcatc gtatattgtt tgataatatt tcttttgata cttcgagttc aggcgtgaca
      121 ttaattactg gtaaaaatgg tacaggaaag tcaactttac tatagtagat tgaaactaga
      181 atagtacaca tctacttcta aaatattgtt agaaatcgat ttgactatcc tgatctattt
      241 gtcctgttct tatttcattt cactatatct caaattgagt atgacgaagt gcgctcccat
      301 gtcctgggaa cgcactttct tcatattttt catattcttg aatccatcga taaagactat
      361 tgggatgaat ttttaaagtt gaactaatca tttttacagg atgagattta cagcagagag
      421 tttgaaggct ttatcaaagg tttttcttgg cataatgact tttcctcgtt tccacttaat
      481 tttgtgtcta ctttattata ccaagtccac ccttaagtta gataataaat ctaacttaag
      541 gaagctagaa ggatgagaat ccaggtggtc aagagtccca aacttaagct gatggggaca
      601 cccagaataa tttgcttttt gaaggcaagg ccacgttcct ctatattggg aagtgagagt
      661 tgaatgagag aaccagctga tgaaaagggt gagatattag tagatagagc gccaataacg
      721 gtggctgttg tgagtaagtg aatatcaatc tgaggatttt gagcactgat gatagcaatg
      781 atgggaaaga gggctggagc tacaacggat agggtggaac taaagagtga catcactccg
      841 gctatcacac aaaagaacag aggtaaccag aaatgaggaa tggttgttgt catgaggtgc
      901 cctatcagtg tgactaaacc tgacttgacc gctagagaca ttagtaagct catgccgcag
      961 agcatgataa ttgtagccca gggaacctta gctaaaatgg cttcttgctt ccctaatttg
     1021 agccttaagg cgaggcagac catgagtatt gagacaaagc caatatcaaa tgttttttga
     1081 taagtagcta tccaggcgat gtttgggaaa atgagatgca acaagggaaa aagccaaacc
     1141 aaaaccatgc tgctgatcat gagcaaggtg gtttgtcttt gaaccttgct gaggagtggt
     1201 ggttggtcaa tagtcaagga tgagtttgtt cttcccttac tatagtgact gtaacaggat
     1261 aataaaagca agacgatgag tgggtagata atgctgacga taaagatatg attgccaagt
     1321 gaaaaagctt gctcttccca tcccatttgc ttaaacaggc cttgaaagac aatgcctgag
     1381 ctactggtta tcaaattagc ccctcctgaa gctccccaat tgacggcttg agctccaatc
     1441 aaagggtgtt tgtccgcttt ttgacagagg gtaatcgcta gaggacagca aacggccata
     1501 gtagtgaaaa atccagcacc taaagcagac aaaagggttg ccatcaggta taaaatcatg
     1561 tagagggcgt tagggtgggt gcgtgtgcgg tagagaatgt gttgagccaa aacatcaaga
     1621 gtaccgttag ttgttgcaac gttataaaag agagagacgc taaaaatggt aaaaaagagt
     1681 gaggttggcc aaaaatgaag aagttctttg gggcttaatc ccatgagagt ggttgcgatg
     1741 aggtaagaaa aagcaatagc cagcaggcca atattgattt tggtgcggta accaattcca
     1801 atggctagag caatggcgct aatcattatt aaatgaatca ttgaattgtc ctttcagtta
     1861 gaatatggaa ataggttggc aattttggcg ctcaaaagac cacctgtttc ctattggtac
     1921 ttgactatta tacacaaaaa aaatacaatt gtcttgacaa ttgtattgac acttgttaga
     1981 attaaaaatg aggtattcag gcttgtgatt tcctatggaa gttaatagta attgcctcta
     2041 gtgcttacaa gtgatattaa aaatagagga cttagtgatg tcaatcattt caactgattt
     2101 aacccctttt caaatagatg atacattgaa agcagccttg cgagaagatg ttcattccga
     2161 agattacagt accaatgcca tttttgatca tcatggccaa gccaaggtgt cgctttttgc
     2221 caaggaagct ggtgttttag cgggactaac cgtttttcaa agggttttta ccctatttga
     2281 tgccgaggtg accttccaga atcctcatca atttaaggat ggggatcgtt tgactagtgg
     2341 cgatttggtt ttagaaatca taggctcggt gagaagtctc ttaacatgtg aacgcgttgc
     2401 cttgaatttt ttacaacatt tatcagggat tgcttcgatg acagctgctt atgtagaagc
     2461 cttaggcgat gattgcatta aggtatttga tactcgaaaa actactccta atttacgtct
     2521 ttttgagaaa tatgccgtga gagttggcgg tggctataat catcgcttta atttatcaga
     2581 tgctatcatg ctaaaagaca atcacattgc ggcagtaggt agtgttcaga aggcaattgc
     2641 tcaagcgcgt gcctatgccc cttttgtgaa aatggtcgag gtggaagtgg aaagccttgc
     2701 tgctgccgaa gaagctgcgg cggcgggtgc tgatattatc atgttggata atatgtcatt
     2761 ggaacagatt gaacaggcca ttaccctaat tgcaggacgt tctcggattg aatgttctgg
     2821 aaatattgat atgaccacta ttagccgttt tcgtggttta gcgattgatt acgtctccag
     2881 tggtagttta acccatagtg ctaagagtct tgatttttcc atgaagggtt taacctacct
     2941 tgatgtctaa gttgtaaaat aaactaactt tttaaaggat gtctttcctc tagaacgagt
     3001 tttatgtcag atagtttaaa cgcctcttca aatatagtaa aatgaaccaa aaatagtaca
     3061 caatgtggta taatcttctt atggcatatt caatagattt tcgtaaaaaa gttctctctt
     3121 attgtgagcg aacaggtagt ataacagaag catcacacgt tttccaaatc tcacgtaata
     3181 ccatttatgg ctggttaaag ctaaaagaga aaacaggaga gctaaaccac caagtaaaag
     3241 gaacaaaacc aagaaaggtt gatagagata gacttaaaaa ctatcttact gacaatccag
     3301 acgcttattt gactgaaata gcttctgaat ttggctgtca tccaactacc atccactatg
     3361 cgctcaaagc tatg
//
LOCUS       DAVLBE010000098         3316 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.098, whole genome shotgun sequence.
ACCESSION   DAVLBE010000098 DAVLBE010000000
VERSION     DAVLBE010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3316)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3316)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3316
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.098"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(<1..422)
                     /locus_tag="VXB91_001966"
     CDS             complement(<1..422)
                     /locus_tag="VXB91_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComB"
                     /protein_id="HEV0471355.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQAT"
     gene            complement(435..2588)
                     /locus_tag="VXB91_001967"
     CDS             complement(435..2588)
                     /locus_tag="VXB91_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEV0471356.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPHKEQKNGLLSFIPI
                     LVKQRGLIANIVLATLLVTVINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEERKTVEDLSLMKGDMTFKQVYYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLIALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
BASE COUNT         1060 a          775 c          593 g          888 t
ORIGIN      
        1 gtggcttggt agccaaactt atcctcctct ggaaagtggt tctccccttc ttgcaggctc
       61 ttttgcagat actccaattg ctttttttga tcctttagca tgtccaactg actggcatag
      121 gactccgctt ggacaccctc tgccccttct tggtattgaa ccaaaagatc ccccttctta
      181 accagcttat tttcttccaa atgattgaca agaatacgat tgttgctagt tgactggata
      241 tttgcaagga tacgactggg ttcgacagta gctctagtgg acaaactcat ctccttctct
      301 gcaacagttg caaagccaag taaaaacacg agcaaaaggg ccatgggtac aatcacacta
      361 ctggaaaaat tatggtaacg acgattataa aactccgcac tttctaaaaa ttctggtttc
      421 atcctctcct ctttctagct attgaccaaa tgggcgtaaa agcctccctg tgcaagcaaa
      481 tcagcatgct ttccttcttc gacaatcttg ccctgatcca agacaaccac cttctctgtc
      541 cgctcagcaa tagtcaagcg gtgagcaatg aaaatcaagg tcttgtccaa agcaatgaga
      601 ttatcgacaa tccgcttctc tgtcaaaata tccaaactgc tagtcgcctc atccaaaatc
      661 aagaccggcg catctgtcaa gagagcacgc gccaaagcga ttctctgacg ttgaccacct
      721 gaaatccctg ccccatccga agtcaattct gtctgataat tcagtggcat gcgctcgata
      781 tcctctcgaa tctctgccaa ttcgaccgcc cgtaagatat cttcctgtgt cgtcccctcc
      841 ttggctccca aaagaagatt ctccaaaatc gttccgttaa agacataggg ctgttgaggc
      901 agatagttga tgtactggcg cagggctttt ttatcaatct gattgagatt gacaccaccc
      961 agactaatct ccccttgact tgggtcgtaa aaattaacca tcatcttggc caaagtcgtc
     1021 ttacctgacc ctgaaatccc cacaaaagcc accttagacc cttggggaac ggttaaattg
     1081 atatccgaca agacgtctcg accatagcca tacttgtaat aaacctgctt gaaggtcata
     1141 tctcccttca tcaagctcaa atcctcaact gttttcctct cctcaaactc agaagctact
     1201 agatacactt catttagacg gttattggca acctgcgctg tctgaagctt ggtttgcaga
     1261 ttgatgatat tttccaaagg attggtaaag taaaccagca aggtattata ggtaatcaac
     1321 tgccccaaac tcatcttgcc atccatgacc agaacagccc ccatccagag aatgccgaca
     1381 ttaagcaaga gatgggcaac ctttttcaga gccttttgct gactctctgc tcgactatag
     1441 gtaaaggatt tcttcagata atccacaaat tccttgtcaa ttttttggta acgctgactt
     1501 tcactggtca aggacttgat agtctcaata ccgttgatgt cctcaatgat agaagaagac
     1561 agaaccgcat tggcttccat ggtatcccga ttcatctttt caaacggctt cataaaggca
     1621 aagataatca ctgtgtagat aggaagcgcc aataaagtca tgaaaaagag attggtattt
     1681 tgtgaaaata gaacaaggga aataatgaca accgttgaca catctaggaa aatcgaaagg
     1741 atggtcgaag ccagcgcatc gatgatactg ttagcatctg taaaacgaga cacgatctcc
     1801 cctgtcctgc gtgtcgcaaa gaaggacata gggaggtgaa aaacatgctt gatataggac
     1861 aaaatcacgt caatcgacaa gcgttgcccc aaaacaagca agagatactc ctgagcgtaa
     1921 gacaagattt gctggaggat gtagacgatg actagcccaa tagaaataat ccctagtgtc
     1981 gaacgcatct gatctggcac ataggtatca atgatagact gcagataata agaacccaca
     2041 atgttaatca cggttaccaa gagtgttgcc aaaacgatat tggcaatcaa gccacgctgc
     2101 ttcactaata tagggataaa agagagcaga ccattttttt gttccttatg aggcttatag
     2161 tctggactag gtgccataaa aagagtcact cctgtccatt cttcctcaaa acgctcacgt
     2221 ggcagtttag tcaacttcac cccgggatct ggatcggcaa tatgaatgct atccttatcc
     2281 tgcccagtca ccacatagta gtggagcaat ttcccttcct taagcacatg ggcaacaaaa
     2341 ggaaaagtca aatccggcaa gtcaaaaagc gtcatatccg ccttaatggc tcgcgtctca
     2401 aaaccaatct cctctgccac cttgaccaag cccaaagccg tcgtcccatc catggtcgtc
     2461 ttagccaatt ctcgcaagtg agccaaaaaa taataactac catagtagcc aaaaaccatg
     2521 gctaatgaag ctacaccgca gtccatctga tccacttgcg gacgatagtg acgtttccca
     2581 aatttcatat tcatctcctt ttccctaata ctcaatgaaa atcaaagagc aaactaggaa
     2641 actagccgca ggctgctcaa aacactgttt tgaggttgta gataggactg acgaagtcag
     2701 tcacatatat acggcaaggc gacgttgacg tggtttgaat ttgattttcg aagagtataa
     2761 actcatctga taacaactat cttaccccaa tcactaaaca aaaactggac ttccttccca
     2821 aatgagccta tctccctccc aactgcactt tttggataaa aaaataggca gaacaaacgt
     2881 tctacctaga aaatataaga attacaagtt aacaaaaccg aaatgatttc atatcattat
     2941 taagtaaaga aaaaaatttt agtatttcta aaaactattt ataatagaca ttatagcatt
     3001 aaataaaaat ggtacagaaa acactactgt caatcttaaa tttttaaatc tcgcataatt
     3061 tgttatccca attagtaata ctgtcaatac gctgaaatag gcaaacttta tatccgatgg
     3121 attaaataaa taacaaagta aaatgctaaa acttaaggtt atatttttag ataaaagaat
     3181 atctccaaag ttcctcttat tcttatcaaa aaataatgta atcagaaaga gagaaaatcc
     3241 atattcaata agagttgcta taaatgtgaa aacaacagaa atcactgtca atattgtttc
     3301 tattttaatt gtaaaa
//
LOCUS       DAVLBE010000099         3199 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.099, whole genome shotgun sequence.
ACCESSION   DAVLBE010000099 DAVLBE010000000
VERSION     DAVLBE010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3199)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3199)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3199
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.099"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(147..758)
                     /gene="rpsD"
                     /locus_tag="VXB91_001968"
     CDS             complement(147..758)
                     /gene="rpsD"
                     /locus_tag="VXB91_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HEV0471357.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(953..2005)
                     /locus_tag="VXB91_001969"
     CDS             complement(953..2005)
                     /locus_tag="VXB91_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEV0471358.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVAKLEKDQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            complement(2002..2700)
                     /locus_tag="VXB91_001970"
     CDS             complement(2002..2700)
                     /locus_tag="VXB91_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0471359.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGCETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQT"
     gene            complement(2867..>3199)
                     /locus_tag="VXB91_001971"
     CDS             complement(2867..>3199)
                     /locus_tag="VXB91_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEV0471360.1"
                     /translation="INVKETSDTANGSLSPSNSGSGVTPMNHNHATGTTDSMPADTMT
                     SSTNTMAGENMAASANKMSDTMMSEDKAMLPNTGETQTSMASIGFLGLALAGLLGGLG
                     LKNKKEEN"
BASE COUNT          898 a          721 c          612 g          968 t
ORIGIN      
        1 tttactatat cactttggac tatatcggtc tagttatgtc taaacgatta tagctggata
       61 ctaagagaaa tcaaaaaagc actaagggag aacgtcccaa agtgcttaat atcaaggcct
      121 caaagcctat cttatttaat aaaatattac aacattttgt tgtagaattc aacgacaagt
      181 gcttcgttga tttctgggtt gatttcgtcg cgttctggca agcgagtcaa tgaaccttcc
      241 aacttttcag cgtcgaatga tacgaatgct ggacgtccaa gagtagcttc tactgcttca
      301 aggattgctg gaactttcaa tgatttttca cgaactgaga tcacttgacc tggagttacg
      361 cggtatgatg ggatatcaac gcgtttcccg tcaacaagga tgtgaccgtg gtttacgaat
      421 tgacgagctt gacgacgagt agtcgcgaga ccaagacggt aaacaacatt atccaaacga
      481 cgttccaaaa gaagcataaa gttgaaacct aggattccac ctttgatttt tgtagcttgt
      541 acgaacaagt tacggaattg tttttcacct acaccgtaag tgaaacgaag tttttgtttt
      601 tcagccaatt gcaaaccata ttctgacaat ttagaacggt tgtttggtcc gtgttgtcct
      661 ggtacatagt tacgacgtgc caattcttta cctgtacctg taagtgaaag gccaaggcga
      721 cgagcttgtt tccaagatgg tcctgtataa cgtgacatat gaatgtcctc ctgatataaa
      781 taatatttcg gtggaaatag tcacttagaa agccctgatt cgtgcagatg cccttcgcct
      841 aaacagccaa ggttacttgt cataagacac ctgttgacga gcttcatgct ttcctgctga
      901 tatttcacac taaattcatt ttaccatgaa tagctggatt tgtaaagggg ttttaggctt
      961 tattttcact accagagagg ttgagaacga gggtaaaggt acttcctaga ccgtactggc
     1021 tgctgactgt gatttcccca cccaattgat gggccaattc acgcgcaatc gcaagtccta
     1081 atccatgacc acctgtcttc atgttacgcg aagtttcgac acgataaagg cgtttgaaaa
     1141 tattttccaa atcctctggg gcaataccct gcccttcatc ggtcacactg attgaaagct
     1201 ggtccttctc cagcttagcc accacttcca gcttggttcc tggagcagaa tatttaaaag
     1261 cgttatcgac cagattcacc aagatacgag aaagcttagc ataatctccc tcaatccggg
     1321 cagactctgg gattacctgc aagtggacat ctcttctctc ctgctcaatc aaaaactgaa
     1381 attcactcat gcactcaatt aagagcttgt ccagaaaaat actgtcttta ctggtagttt
     1441 ccacctgatt tctagctgtg tttagggtca aaaaattcaa ctcctcaacc agtttattga
     1501 gcctctccgt ctggcgtcca atggttgcta gataatgagc ttgctccgac tccttgataa
     1561 taccatccaa aatcccttct accgtcgctt ggatcgaagt gataggagtc ttaatatcat
     1621 gcgacaactg ggcaatcatc aagccctttt ctcgttcgct ttcttccaag gaatcaaagc
     1681 ttacctgcaa atcatgggac atctcattaa aagtttgccc taattgctga aattctacag
     1741 gaccttgaac ctccaaattt gaaggaaaat ccttggccgc tacccgcttg gcatgctcct
     1801 tgagtttgcc caacgacgta aagactggca ataggagaaa gagactaatc ccagcaccga
     1861 caaggctggc aacgatggtc atcccaagca aaaagtaaat ctcgcctttc gcaatcagca
     1921 ttttttgaac agcccaaaaa acaaccaaaa tggttaagag ggttgaaata atatatccaa
     1981 ccaaaatata actttttagt ttcatgtttg tcctctcggt ttctctatct tatatcccaa
     2041 cccccaaact gtcttaatag tgggcgtttg gtcactacta tattttgcca gctcctgtcg
     2101 aagagcatgg atatgcacat tcaaggtatt ggtgtcatcc acgtagtctt ctttccagat
     2161 cttttcatag aggtctgtct tggagaaaac tcgctctgga ttgctagcta aaatccacag
     2221 caattcaaat gatttaacag ttaaatccag catttcttct cctatttgaa cttcatgact
     2281 actatgattc atttttagat tgccaaggga aatcagctct gtttcgcacc cacgatgaag
     2341 gcggcgcaaa atattgtgga cacgcaaaac tagctcacgt gggctaaaag gcttagcaat
     2401 aaaatcatct gctcccaagc tcaggccgta aatcttgtcc tgttcactgg tcttagcagt
     2461 aataaatagg aaaggctgct ctggtgataa gtattgaacc tcactgatta aatcataacc
     2521 atccatccga ggcatcatga catctgtgat aatcaaatca atcggttttt tcttgaacag
     2581 ctctagcgct tccagtccat catgggctac caagacctga taacctgcct gaattaagta
     2641 tctctgatga atatctgtga tttctacctc gtcgtcaacg agtaaaattg tctttcccat
     2701 ctgtctctcc tttgataaaa acagtgctat actgctttaa gtataacact atttttattg
     2761 ttttacgatg attttaatct gctattgaaa gaaagtcctg attgctgatt gagttgttaa
     2821 actaatctta gtcagcccac tatccatcat ttatttcctt agctgattag ttttcttctt
     2881 ttttgttttt caaacctaga ccaccgagta aacctgcaag cgcaagccca aggaaaccaa
     2941 tacttgccat tgatgtttga gtctcaccag tatttggtag catagcttta tcctctgaca
     3001 tcatcgtatc agacatcttg ttagcagaag cagccatgtt ttcacctgcc atcgtgttgg
     3061 tagaacttgt catggtgtca gcaggcatgc tatctgtagt acctgtagca tgattgtgat
     3121 tcatcggagt cacgccagaa ccagagttag aaggtgataa tgaaccattt gctgtgtctg
     3181 atgtttcttt aacatttat
//
LOCUS       DAVLBE010000100         2990 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.100, whole genome shotgun sequence.
ACCESSION   DAVLBE010000100 DAVLBE010000000
VERSION     DAVLBE010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2990)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2990)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2990
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.100"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(164..892)
                     /locus_tag="VXB91_001972"
                     /pseudo
     CDS             complement(164..892)
                     /locus_tag="VXB91_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
     gene            complement(1152..1463)
                     /locus_tag="VXB91_001973"
     CDS             complement(1152..1463)
                     /locus_tag="VXB91_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0471361.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYDCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCLFCFSRFNPGCQNHKERYF
                     K"
     gene            complement(1478..2764)
                     /locus_tag="VXB91_001974"
     CDS             complement(1478..2764)
                     /locus_tag="VXB91_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEV0471362.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFAAKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     ALIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMEELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYDLYDMPFGKERKSL
                     QGEIPEEFSMSAVDMSMIDHIPDMIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     LESPEKFEAIKQDLVDEMWKVAQRELATGFYYGIPSENEQLFGARRKIPEYKFVAEVV
                     SYDDAVQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDLHDAKGNKIDRAPNPMELL
                     TIKVPQPVQSGDMVRALKEGLINFYKEDGTSVTVRA"
BASE COUNT          893 a          656 c          527 g          914 t
ORIGIN      
        1 tgtttaattt gataggcttt aatacctaag ctccgacttt atcacttaaa aaataaaaaa
       61 ggacagctaa tctcttgcgc atcaagggat ttcgccattc tttaatctcg tttaagtgtt
      121 gtatatggag ctttgcataa ttttttaaaa ctaaacaact acattaagca cgaactgtga
      181 cgctggttcc atcttcctta taaagattga taagcccctc tttaagagct cgaaccatgt
      241 ctccagcttg aacaagttgt gggactttaa tagtcaatag ttccattgga tttggagcgc
      301 ggtcgatttt attgcctttg gcatcatgca aatcttcaat ataggtttca aaatgacgga
      361 aacctggacc ataaaactca acttggtccc cttcgttaat gacgttccgt tgacgaatgg
      421 ttgctgtttg tgtcgcatca tcataagaaa ccacttcagc gacaaacttg tactcaggga
      481 ttttacgacg agcaccaaac aactgctcat tttcagatgg tgtaccatag taaaatcctg
      541 tagccagttc acgttgggca accttccaca tctcgtccac caagtcttgt ttgatagctt
      601 caaacttttc aggactttca agataggcat ccacagccgc cttgtagcag ttggttactg
      661 ttgatacata gtgaatagac tccatacgtc cttcgatttt tagactgtcc acaccatttt
      721 caatcatatc tgagatatgg tcaatcatag acatatcaac ggctgacatt gaaaattctt
      781 ctggaatctc accctgcaaa ctcttacgtt ctttcccaaa tggcatatcg taaaggtcgt
      841 acttccaacg gcatgactga gaacatccac cacggttggc atcacgcata ctctagacgg
      901 attgttttga caattctaac cttttagact ttgcataata actgttaaac agtcgaaaat
      961 taccccagtt ttaacaagta gtcaaaatac cagataaagt aaaaaggggc taggaaaaaa
     1021 gtctttaaaa tcttaaaaac gcatagtatc aggtattgaa caatcttgat attatgcgtt
     1081 ttattgtggg aagatttact tcattttctc ttggaattga gttttctcct acttcaaaac
     1141 tagatgattt gctatttaaa atagcgttcc ttatgatttt ggcaacctgg attaaagcga
     1201 gaaaaacaaa agaggcaact taagctttct ttatattgct tatatgttaa tagttttaga
     1261 caaacaccac ataaaatagg cttatcctgt atcaaagata agggataagg ctcaaaaggg
     1321 tgattttcta atgaatcatg acaccgataa caagcataat actttttaca atcatagcat
     1381 tgtaaagcaa taatatccag cttgctatgg taatgaatgc atcttgtttg cttatccact
     1441 aagaaaccct gtgcctctat catttccttt tcctttctta agctcgaact gtgacgctgg
     1501 ttccatcttc cttataaaaa ttgatgagtc cttcttttaa tgcacgaacc atgtctcctg
     1561 attgaacggg ttgtgggact ttaatagtca atagttccat tggatttgga gcgcggtcga
     1621 ttttatttcc tttggcatca tgcaaatctt caatataggt ttcaaaatga cggaaacctg
     1681 gaccataaaa ctcaacttgg tccccttcgt taatgacgtt tcgttgacga atggttgctg
     1741 tttgtaccgc atcatcataa gaaaccactt cagcgacaaa cttgtactca ggaattttac
     1801 ggcgagcacc aaacaactgc tcattttcag atggtatacc gtagtagaaa cctgttgcca
     1861 attcacgttg ggcaaccttc cacatctcgt ccaccaagtc ttgtttgata gcttcaaact
     1921 tttcaggact ttcaagatag gcatccacag ccgccttgta gcagttggtt actgttgata
     1981 cgtagtgaat agacttcata cgtccttcga tttttagact gtccacacca ttttcaatca
     2041 tatctggaat gtggtcaatc atagacatgt caacggctga cattgaaaat tcttctggaa
     2101 tctcaccctg caaactctta cgttctttcc caaatggcat atcgtaaagg tcgtatttcc
     2161 aacggcatga ctgagaacat ccaccacggt tggcatcacg catactcatg tggtttgaaa
     2221 gagtacaacg tccagagtat gaaatacaca tagctccatg gacaaaggct tcaatttcaa
     2281 catctgtacg tttgcggatc tcagctaatt cttccattga aacctcacgc gctaaaacga
     2341 cacgagtcaa gcctagctct ttccagaact caagggtttc atagttagtg gcactggctt
     2401 gggtagaaag gtggatttca aggcctggtg cttcagtcgc tgcaatcata atcaaggctg
     2461 ggtcagatac gataactgct gcaatcccga tatcacgcag tttacggaac cactcaccag
     2521 caccagcttc atttccttcg tgcataacca tattagccgc tacatagacc ttggcaccat
     2581 acttggccgc aaactgcacg ccttcttcca tctgttcgaa agtaaagttt cccgcacggc
     2641 tacgaagacc ataggcctga ccaccgataa agacagcatc tgctccatac tgaacagcta
     2701 cctttagctt ctctaaagtc cctgcaggtg ataaaacctc aggacgtttt aatgtttttg
     2761 tcatgatttc tcctatttgc aatataaaag tttgacattt ttccttctca ttttatagta
     2821 aataaaggat aaaatcaagc ctagacggat tgttttgaca attctaatct tttagacttt
     2881 gcataataac tgttaaacag tcgaaaatta ccccagtttt aacaagtagt caaaaagtct
     2941 aaaaaagtaa aaaccagtat cccaagatac tgactcgtaa aaatacataa
//
LOCUS       DAVLBE010000101         2967 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.101, whole genome shotgun sequence.
ACCESSION   DAVLBE010000101 DAVLBE010000000
VERSION     DAVLBE010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2967)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2967)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2967
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.101"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(150..683)
                     /locus_tag="VXB91_001975"
     CDS             complement(150..683)
                     /locus_tag="VXB91_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HEV0471363.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
     gene            complement(772..1548)
                     /gene="recX"
                     /locus_tag="VXB91_001976"
     CDS             complement(772..1548)
                     /gene="recX"
                     /locus_tag="VXB91_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HEV0471364.1"
                     /translation="MKITKLEKKKRLYLMELDNGDKCYITEDTIVRFMLSRDKVISEE
                     ELKEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDKNIVSQVIANLKEDKW
                     INDGQYAYAIINTNQLSGDKGPYVLTQKLSQKGISKSTIEENLKEFDFSEVAQRVANK
                     LLKKYEGKLPARALQDKIIQNLTNKGFSYSDAKIAFDDLDSQVDQETTQELIFKELDK
                     QYTKYARKYEGYELKQRLTQVLARKGYDFSDIASALREYL"
     gene            1586..2941
                     /gene="rlmD"
                     /locus_tag="VXB91_001977"
     CDS             1586..2941
                     /gene="rlmD"
                     /locus_tag="VXB91_001977"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEV0471365.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCTIYNECGGCQIMHLHYDKQLEFKTDLLHQ
                     ALKKFAPAGYENYEIRPTIGMQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELK
                     DCLVQDKETQVIANRLAELLTYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNR
                     QLNLTQLVKELVKDFPEVVTVAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLNYEFSL
                     SPRAFYQLNPEQTEVLYSEAVKALDVDKEDHLIDAYCGVGTIGFAFAKKVKTLRGMDI
                     IPEAIEDAKRNAKRMGFDNTHYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLL
                     DTILTYVPEKMVYISCNVSTLARDLVRLVEVYDLHYIQSVDMFPHTARTEAVVKLIKK
                     V"
BASE COUNT          939 a          531 c          542 g          955 t
ORIGIN      
        1 ttatatattt tacgaattct gcataaatct ctttctagta atgtgttgta actctgctat
       61 aatggattta ttcctttttg tatttacaca atttatttta tactaccaaa aaaacaaggt
      121 caggattttg ttcctgacct ttgacaactt taccgattct ttagttctac atagcgcttg
      181 taccaaatgt ttacataggc ttctgagaaa ggaccacgtc cattgttaat ccaatcaaca
      241 agaattttga catgttcttt taaaatatag tccaagtcat cagaataatt cattttgcgt
      301 ttgtgacgct cgtattcttc aacgtccaag agacgttttt ccccatctgt aaaaatttta
      361 acatccaaat cgtaatcaat atacttcagt gcttcttcat ccagatagta ggggctagcc
      421 atattgcaat agtaagaagt tccattatca cgaatcatgg caatgatatt aaaccaatat
      481 ttcttgtgaa agtaaacaat agccggttct cgagtgaccc aacgacgacc atcactttcg
      541 gtaacaagtg tatgatcgtt gacaccaata atggcgtttt ctgttgtttt tagtaccatg
      601 gtgtcccgcc aagttcggtg gagactccca tcatgcttat aactttgaat tgtaataaag
      661 tcgccttctt ttggaagctt cataactaac caactttcta caatttataa gtttatcatt
      721 tactattgta ccataaaatt acctaaaatc tgtgaatttc acttggaaat attaaagata
      781 ttctctaaga gcgcttgcta tatccgaaaa atcgtagccc tttcgtgcta aaacttgagt
      841 taaacgctgc ttcagttcgt atccttcata ctttcgagca tacttagtat attgcttatc
      901 aagttccttg aagatgagtt cttgagtcgt ttcttggtca acttggctat ctaagtcgtc
      961 aaaggcaatt ttagcatcag aataagagaa gcccttgtta gtcaagttct ggataatctt
     1021 atcttgcagg gcacgagctg gaagttttcc ctcatatttt ttcaatagtt tattggctac
     1081 acgttgagca acttcagaaa aatcaaattc tttcaagttc tcttctatag tagattttga
     1141 aatccctttt tgagatagtt tctgagtcag cacataagga cccttgtctc ctgaaagttg
     1201 attggtattg atgatagcat aagcgtactg accatcatta atccacttat cttctttaag
     1261 attagcaata acttgagaaa cgatgttttt atcaatatcg tattttttca gatattctct
     1321 gacttctttt tcagtgcgtg ctttaaagga taagtggtag agagcgagat tcttaccata
     1381 agaaaattga gcaaagtctt gaatctcttt caattcctct tcgcttatca ccttatctct
     1441 cgataacata aaacgaacaa ttgtatcttc ggtgatatag catttgtcgc cattatcaag
     1501 ctccatcagg tagagtcttt ttttcttttc aagttttgtg attttcatag ctctattata
     1561 actcaaaatg tgataagata ggggtatgaa tctgaaagtg aaacaaaaaa taccattaaa
     1621 aatcaagcgc atgggaatta acggtgaggg aatcggcttt taccaaaaaa cattagtctt
     1681 tgtaccagga gctctcaaag gcgaagatat ctattgtcag attacttcta ttagacgcaa
     1741 ctttgttgaa gcaaaattac tgaaggtcaa caagaagtct aaatttcgaa ttgtgccatc
     1801 ttgtactatt tataatgaat gcggaggctg ccaaatcatg cacctgcatt atgataagca
     1861 gctggagttc aagacggact tacttcatca agcgctgaaa aaatttgctc ctgcaggata
     1921 tgaaaattat gaaattcgtc caactattgg aatgcaggaa ccaaaatatt acagagctaa
     1981 gttacaattt cagactcgaa aatttaaaaa tcaggtcaag gcgggcttat atgcacaaaa
     2041 ctctcactat ttagtagagt tgaaagactg cctggtacaa gataaggaaa cccaagtgat
     2101 tgctaatcgc ttagcagaat tacttactta tcaccagatt ccaatcacgg atgagagaaa
     2161 agttctaggt gtccgtacta ttatggtccg acgcgcgaga aagaccggac aggttcagat
     2221 tattattgtt acaaaccgcc agcttaattt aactcaattg gtaaaagagt tggttaaaga
     2281 tttcccagaa gttgtgacag tagctgttaa tacaaataca gctaaaacca gtgagatata
     2341 tggtgaaaag acagagatta tctgggggca agagagtatt caagaaggtg tactcaatta
     2401 tgaattttca ctatcccctc gagcttttta tcaactaaat cctgagcaaa cagaagtcct
     2461 ctatagcgaa gcagtaaaag cgctggatgt tgataaagaa gaccatttga ttgacgctta
     2521 ttgtggagtt ggaacgattg gatttgcctt tgcaaagaaa gttaaaacac tcagaggtat
     2581 ggatattatt ccagaagcta ttgaagatgc caagcgaaat gctaaaagaa tgggatttga
     2641 caatactcat tatgaagctg gaacggcaga agagattatt cctcgttggt acaaggaagg
     2701 ctaccgagca gatgctttga ttgttgaccc accacgtaca ggtctggatg ataagttatt
     2761 agatactatt cttacttatg taccagaaaa aatggtttat atttcttgta atgtttcgac
     2821 cttggctcgt gatttggtac gcttagtaga agtctatgat cttcattata tccagtcggt
     2881 cgatatgttc ccacatacag ctcgaactga agctgttgta aaattaataa aaaaagttta
     2941 aaaaagtagt tgacaaagtt tgaaaag
//
LOCUS       DAVLBE010000102         2722 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.102, whole genome shotgun sequence.
ACCESSION   DAVLBE010000102 DAVLBE010000000
VERSION     DAVLBE010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2722)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2722)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2722
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.102"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            67..390
                     /gene="tnpB"
                     /locus_tag="VXB91_001978"
     CDS             67..390
                     /gene="tnpB"
                     /locus_tag="VXB91_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEV0471366.1"
                     /translation="MTIHLSSLGEVYLVCGKTDMRQGIDSLAYLVKTHFELDPFSGQV
                     FLFCGGRKDRFKVLYWDGQGFWLLYKRFENGRLIWLSTEKDVKALTPEQVDWLMKGFS
                     ITPKI"
     gene            complement(545..853)
                     /locus_tag="VXB91_001979"
                     /pseudo
     CDS             complement(545..853)
                     /locus_tag="VXB91_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            844..1284
                     /locus_tag="VXB91_001980"
     CDS             844..1284
                     /locus_tag="VXB91_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0471367.1"
                     /translation="MKSPIPKAPLAHNFGSASIIAHTIHQKFNLKVPNYRQEEDWARM
                     GLPITRKEISNWHIKASQYYLEPLYNLLRERLLTQPLLHADETSYRVLESDSQLTYYW
                     TFLSGKAEKQGITLYHHDQCRSGSVVQEFLGDYSGYVHCDILRQ"
     gene            1379..1808
                     /locus_tag="VXB91_001981"
                     /pseudo
     CDS             1379..1808
                     /locus_tag="VXB91_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014295150.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1879..2037
                     /locus_tag="VXB91_001982"
     CDS             1879..2037
                     /locus_tag="VXB91_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase domain-containing protein"
                     /protein_id="HEV0471368.1"
                     /translation="MSLLETAKRHQLNSEKYLSYLLECLPNEETLVNKEVLEAYLPWT
                     KVVQEKCK"
     gene            2130..2722
                     /locus_tag="VXB91_001983"
                     /pseudo
     CDS             2130..2722
                     /locus_tag="VXB91_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          831 a          508 c          568 g          815 t
ORIGIN      
        1 aagtaagttt ttttcaatct ctcaatctcg aaatggtaga acagcttttg gataaggtgt
       61 tgctctatga caattcatct atctagccta ggggaggtct atctcgtgtg tgggaaaact
      121 gatatgagac aaggaatcga ttcactggct tatctggtta aaacccactt tgaattggat
      181 cctttctccg gtcaagtctt tctcttttgt ggtggacgta aagaccgctt taaagtcctt
      241 tactgggatg gtcaaggatt ttggctacta tataaacgct ttgagaacgg cagattgatt
      301 tggctaagta cagaaaagga tgtcaaagct ctcacaccag aacaagtaga ctggcttatg
      361 aagggctttt ctatcactcc aaaaatatag tagattgaaa ctagaatagt acacctctgc
      421 ttctaaaaca ttgttagaaa tcgattttac tgtcctgatc gatttgtcct gttcttattt
      481 cattttacta taaatccatc agaaagtcgt gatttctatt gaaatgagga ctttcttttt
      541 atactcatct gctttcaaaa agcattctag tccatctccg attaacgatg gactttatca
      601 cctccttctc cagtccttgt ataacatctt ggagttgatt catgacatct tccaaagttt
      661 aaaaggcttt attcttaaat ccacgtttac gaatctcttt ccacacttgt tcaatggggt
      721 tcatctctgg tgtgtatgga ggaataaatg caaagccaat attagtcgga atctttaagg
      781 tacttgattt atgccatata gcattgtcca taacgagtaa aagataatca tctggataag
      841 cttgtgaaat ctcctattcc taaagcccct ttagcgcata actttggctc agcttctatt
      901 atcgctcaca ccatccatca gaagtttaat ctgaaggtac ccaattatcg ccaagaagaa
      961 gattgggcta ggatgggttt accaatcaca cgtaaggaaa tctctaattg gcatatcaag
     1021 gcgagtcaat actatttgga gcccctttat aacctcttgc gagagagact attgactcag
     1081 cccttacttc atgcggatga aacttcttat agggtgctag agagtgatag tcagctgact
     1141 tactattgga cttttttgtc aggtaaagca gagaaacaag ggattacgct ttaccaccat
     1201 gatcagtgtc gaagtggttc agtagtacaa gaattcctag gagattattc tggctatgtg
     1261 cattgtgata ttttgcggca gtaacttagg actttagtcc tctagttctg cctatgcgat
     1321 agcagtccaa ggtttaggag caaggcgacg ctaagcttgg taaacttcga accgctcgtc
     1381 tgcttatcgt caactggaag aagctgaact tgttggatgt tgggcgcatg tgagaaggaa
     1441 gttttttgaa gcgccccccc aagcaagcgg ataaatcatc cttaggagct aaaggtttag
     1501 cttattgtga tcagttattt tccttggaaa gagactggga ggctttgcca gctgatgaac
     1561 gactacagaa acgtcaagaa catctccagc ccttaatgga agacttcttt gcttagtgcc
     1621 ggcgtcagtc agttttagca ggttcaaaac taggaagggc aattgaatac agcctcaagt
     1681 atgaagaaac ctttaagacc attttgaaag acggacatct ggtcctttcc aataatctag
     1741 ctgaacgcgc cattaaatca ttggttatgg gacggagtaa aagagtccag tggactcttt
     1801 tagcctaagc tcagtttaaa aaagcgaggg tggttatttt ctcaaagttt tgaaggagct
     1861 aaagcaagag ctattattat gagtttgttg gaaacagcta aacgtcatca attaaatagc
     1921 gagaaatatc tatcctatct tctagaatgt cttccaaacg aggaaactct cgtaaacaaa
     1981 gaggttttag aggcttattt accatggact aaagttgtac aagaaaagtg caaataagaa
     2041 atctccagat taggaactat ccgtgagttc tccagtctgg agatttttca atagacttcc
     2101 tgcgaaacaa aatatggtat aatagttcta tgaatgatga agcaagtaaa caactaaccg
     2161 atgcacgatt taagcgtctt gttggtgttc aacgcacgac ttttgaagag atgttagctg
     2221 tattaaaaac agcttatcaa cttaaacacg caaaaggtgg acgaaaacct aaattaagtc
     2281 tagaagacct tcttatggcc actcttcaat atgtgcgaga atatcgaact tatgaacaaa
     2341 ttgcggctgt ttttggtatt cacgaaagca acttaatccg tcggagccaa tgggttgaag
     2401 taactcttgt tcaaagtggt gttacgattt caagaactcc tctcagttct gaggacacgg
     2461 taatgattga tgcgacggaa gtaaaaatca atcgccctaa aaaaagaatt agcgaattat
     2521 tctggtaaaa agaaatttca cgctatgaag gctcaagcga ttgtcacaag tcaagggaga
     2581 attgtttctt tggatatcac tgtgaactat tgtcatgata tgaagttgtt caaaatgagt
     2641 cgcagaaata tcagacaagc tggtaaaatc ttggctgaca gtggttatca agggctcatg
     2701 aagatatatc ctcaagcaca aa
//
LOCUS       DAVLBE010000103         2647 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.103, whole genome shotgun sequence.
ACCESSION   DAVLBE010000103 DAVLBE010000000
VERSION     DAVLBE010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2647)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2647)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2647
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.103"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            217..1413
                     /gene="tuf"
                     /locus_tag="VXB91_001984"
     CDS             217..1413
                     /gene="tuf"
                     /locus_tag="VXB91_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEV0471369.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
     gene            complement(1522..2647)
                     /locus_tag="VXB91_001985"
                     /pseudo
     CDS             complement(1522..2647)
                     /locus_tag="VXB91_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
BASE COUNT          811 a          516 c          562 g          758 t
ORIGIN      
        1 ctaaaaaatg cttggactac aagtcgccaa gtgaatttct tttgggtggc taacttcaac
       61 ttgaaatttg gggttaaatt tttaccaaga ataattcaca aaaacgttgt aaaacacttg
      121 caatttagct gaaatttgat aaaatagtaa ggaaagttag actgtattgc ctactgtcta
      181 tctataaaat atattttatt ggaggctttt actcaaatgg caaaagaaaa atacgatcgt
      241 agtaaaccac atgttaacat tggtactatc ggacacgttg accacggtaa aactacccta
      301 actgcagcta tcacaactgt tttggcacgt cgcttgcctt catcagttaa ccaacctaaa
      361 gactatgcgt ctatcgatgc tgctccagaa gaacgcgaac gcggtatcac tatcaacact
      421 gcgcacgttg agtacgaaac tgaaaaacgt cactacgctc acatcgacgc tccaggacac
      481 gcggactacg ttaaaaacat gatcactggt gctgctcaaa tggacggagc tatccttgta
      541 gtagcttcaa ctgacggacc aatgccacaa actcgtgagc acatccttct ttcacgtcag
      601 gttggtgtta aacaccttat cgtcttcatg aacaaagttg acttggttga cgacgaagaa
      661 ttgcttgaat tggttgaaat ggaaatccgt gacctattgt cagaatacga cttcccaggt
      721 gacgatcttc cagttatcca aggttcagca cttaaagctc ttgaaggtga ctctaaatac
      781 gaagacatcg ttatggaatt gatgaacaca gttgatgagt atatcccaga accagaacgt
      841 gacactgaca aaccattgct tcttccagtc gaggacgtat tctcaatcac tggacgtggt
      901 acagttgctt caggacgtat cgaccgtggt atcgttaaag tcaacgacga aatcgaaatc
      961 gttggtatca aagaagaaac tcaaaaagca gttgttactg gtgttgaaat gttccgtaaa
     1021 caacttgacg aaggtcttgc tggagataac gtaggtgtcc ttcttcgtgg tgttcaacgt
     1081 gatgaaatcg aacgtggaca agttatcgct aaaccaggtt caatcaaccc acacactaaa
     1141 ttcaaaggtg aagtctacat ccttactaaa gaagaaggtg gacgtcacac tccattcttc
     1201 aacaactacc gtccacaatt ctacttccgt actactgacg ttacaggttc aatcgaactt
     1261 ccagcaggta ctgaaatggt aatgcctggt gataacgtga caatcgacgt tgagttgatt
     1321 catccaatcg ccgtagaaca aggtactaca ttctctatcc gtgagggtgg acgtactgtt
     1381 ggttcaggta tggttacaga aatcgaagct taattcgatt tagttcccag aagaacaatt
     1441 atttaagtca gacactaaaa gaatcttgct tggcaaggtt cttttttggt tctttgtcaa
     1501 ctgtagtggg ttgaaaaaaa gctaagctcg agaaaggaca aatttcgtcc tttctttttg
     1561 atgttcaggg cgatgaaaat ccgttttttg aagttttcaa agttccgaaa accaaaggca
     1621 ttgcgcttga taagtttgat gagattattg gtcgcttcca atttggcgtt tgaatagggt
     1681 agttgaaggg cgttgacgat tttctctttg tcctttagaa aggttttaaa gacagtctga
     1741 aaaagaggat gaacctgctt aagattgtcc tcaatgagtc cgaaaaattt ctccggttcc
     1801 ttattctgaa agtgaaacag caagagttga tagagctgat agtggtgttt caagtcttcc
     1861 gaataactca aaagcttgtt taaaatctct ttattggtta agtgcatacg aaaagtagga
     1921 cgataaaatc gcttatcact cagtttacga ctatcctgtt gtatgagctt ccagtagcgc
     1981 ttgatagcct tgtattcatg agactttcga tgaaactgat tcatgatttg gacacgcaca
     2041 cgactcatag tacggctaag atgttgtaca atgtgaaagc gatcaagaac gattttagca
     2101 ttcgggagtg aaacagtctg ggagactgtt tcagcctgag cctagaaatt tgaaagcgaa
     2161 gctgtttagc taagtcatag taaggactaa acatatccat agtaataatt ttgacgcgac
     2221 atcggacggc tctatcatat ttaagaaagt gatctcggat gacagcttgt gttctaccct
     2281 caagaacagt gatgatattg agattgttaa aatcttgcgc aatgaagctc atctccatct
     2341 cccgattgaa acagtcactc cccggactgt ttcaacgtcc caggacataa tctcaggaag
     2401 acgcgaaaaa tcatgctcaa agtgagaatc attgagcttg cgaatgacag ttgaagttga
     2461 gatggaaagc tgatgggcaa tatcagtcat agaaatcttt tcaattaact tttgagcaat
     2521 cttttggttg atgatacgag ggatttggtg attcttcttg acgatagaag tttcagcgac
     2581 catcattttt gaacagtgat agcacttgaa tcgacgcttt ctaaggagaa ttctagtagg
     2641 catacca
//
LOCUS       DAVLBE010000104         2485 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.104, whole genome shotgun sequence.
ACCESSION   DAVLBE010000104 DAVLBE010000000
VERSION     DAVLBE010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2485)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2485)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2485
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.104"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(70..783)
                     /locus_tag="VXB91_001986"
     CDS             complement(70..783)
                     /locus_tag="VXB91_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HEV0471370.1"
                     /translation="MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFSHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIERDYDLYAATNGITAIQTGRLAQSGLAPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            complement(1241..1621)
                     /locus_tag="VXB91_001987"
                     /pseudo
     CDS             complement(1241..1621)
                     /locus_tag="VXB91_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443785.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
     gene            complement(2038..>2485)
                     /locus_tag="VXB91_001988"
     CDS             complement(2038..>2485)
                     /locus_tag="VXB91_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HEV0471371.1"
                     /translation="RNKNGQADTNQTEKPNEEKPQTEKPEEDKEHDEVSEPTHPESDE
                     KENHAGLNPSADNLYKPSTDTEETEEEAEDTTDEAEIPQVEHSVINAKIADAEALLEK
                     VTDSSIRQNAVETLTGLKSSLLLGTKDNNTISAEVDSLLALLKESK"
BASE COUNT          754 a          502 c          395 g          834 t
ORIGIN      
        1 aacttcagac atttcaatgt actcttcaat agtaatatta gcttttttgt agtcattagc
       61 tcgtctcctt taaaatgtga tcttttcaag aatattttta tctaaacaat ccagcaagtc
      121 ttggtaagaa tagacttcgt aagtcggctg ggcttgtgtg tgattttcga ggtgatgagg
      181 attataccag atagtgtcaa tccccgcatt attgccacct tgaatgtcgg cggttagaga
      241 atctccaatc atcagcgtct tttctttact aaatccagca atttgctggc caatcttttc
      301 ataaaaaaga gcatccggct tttgagtttg caactgttct gagataaaga cttgattgaa
      361 ataaggtgct agaccagatt gagccaaacg tcctgtctga atggcagtaa tgccatttgt
      421 cgcagcatac aagtcataat cacgctcaat gaggctgtcc aagagatcat gagcgcccga
      481 tagtgtttgt ccctgctgag cgagataaaa ttggtaacgc tgggcaagaa aactaccgtc
      541 tttttcctgt ccaaaatgag aaaataaacg agaaaagcgc gtgttaacca gctcttgttt
      601 actgattttc ttcagctcca agtctttcca gagagccttg ttcataggaa cgtaataatc
      661 tttataagcc tgaatatccg caactccttc ttcttttaga agttgggtca aagccacatc
      721 ctcagcagca tcaaaatcaa gaagagtgtg gtcgaggtcg aagagtagaa atttgtagaa
      781 caatttgagg ttttcctttc tgaaaattca ttaagaacat tatatcataa agcacctcat
      841 acaattaact aatttaatca cttaaaaaaa ttcgaacact ttctatacaa ctgacagctc
      901 aaatctttca gaatagaaca atactaacta tcgagcaccc cgtattcata aatatatgtg
      961 taattctaga cctagaattc ctataaacta aatgctttca tactcttcca agtaattgat
     1021 tgccttaaat tttaattttt gaaggtttct aaagctagaa tagccccatc acaatcagtt
     1081 ttgattgatt cacaatttag aaacactata gtttcactcc tgttaaaata aaaaggaact
     1141 gcataaagca atccctttct gattttgaaa tcatttactt aacattttat agttgagata
     1201 atcaatagct tacctataaa aagagttata gtaaaattcc ttatttattg atttcaagct
     1261 ccgctaactg tgtttgaata actgacagtt ctgcaccagc ctgaagaaga gcagctgcat
     1321 tataggcacc ttctacaatt ggaaccctgt tgatgatgat acttttatca ctgaaatcag
     1381 tcaccatttt taagttcatt ttagcagaac ctaggtcaaa aaaggcaagt aaagtatctg
     1441 ctgtattttc ggaaacaacc ctatctactt aatcaaaact cgttccaatt cctccgccct
     1501 cggttcctcc tacataagta atcggaacat ctttagctac tttactaatc agttcaacaa
     1561 caccttctgc aatgtgtttg gaatgtgaaa cgataacaag accaatacca atactttcca
     1621 tcaaaccacc ccagtttcta aaatagcagt aaagagtaat cctgatgaga atgatccagg
     1681 atcaatatgt ccaagaaacc atatgctcct aagacaagag ccaacagact ggtcatcaat
     1741 aatagtattg ttcttttttt catcattact ccttaactag tgtttaactg attaattagc
     1801 cagtaaatag tttatcttta tttacactat ctgttaagat atagtaaaat aagaacagga
     1861 cagtcaaatc gatttctaac aatgttttag aagtagaggt atactattct agtttcaatc
     1921 tactatattt tgcacatttt catgaaaaaa atgagaacta gaactcacat tctgctctca
     1981 tttttcgttt tcccgttctc ctatcctgtt tttaggagtt agaaaatgct gctaccttta
     2041 cttactctcc tttaataaag ccaagagact atctacttct gctgaaatag tgttattatc
     2101 tttcgttccg agaagaagac tactttttag accagtcaat gtctccacag cattttgtct
     2161 aatactagaa tctgttactt tttctagcaa ggcctccgca tctgctatct tagcgttaat
     2221 aacagaatgc tctacttgag gaatttcagc ctcatctgta gtatcttcag cttcttcctc
     2281 tgtctcttcc gtatcagtgc ttggtttata aagattatct gctgaaggat ttaaaccagc
     2341 gtgattctct ttttcatcag attcagggtg agttggctca cttacttcat catgttcctt
     2401 atcttcctca ggtttttctg tctgaggttt ctcctcgttt ggtttttccg tttgattggt
     2461 atcagcttga ccatttttgt ttctt
//
LOCUS       DAVLBE010000105         2435 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.105, whole genome shotgun sequence.
ACCESSION   DAVLBE010000105 DAVLBE010000000
VERSION     DAVLBE010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2435)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2435)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2435
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.105"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            15..1040
                     /locus_tag="VXB91_001989"
     CDS             15..1040
                     /locus_tag="VXB91_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HEV0471372.1"
                     /translation="MKNKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDH
                     AFGQTILDKKPERVATIAWGNHDVALALGIVPVGFSKANYGVSADKGVLPWTEEKIKE
                     LNGKANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQT
                     LWRDMIKIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAAD
                     TSKFWIYTSKDPRANYLTDLGLVFPESLKEFESEDSFAKEISAEEANKINDADVIITY
                     GDDKTLEALQKDPLLGKINAIKNGAVAVIPDNTPLAASCTPTPLSINYTIEEYLNLLG
                     NACKNAK"
     gene            1030..2037
                     /locus_tag="VXB91_001990"
     CDS             1030..2037
                     /locus_tag="VXB91_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV0471373.1"
                     /translation="MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLAAFG
                     MGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGAS
                     LSVVIGLSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSM
                     ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLN
                     ALAMGDEMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISK
                     DIRTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTMKNRGVN
                     N"
     gene            2037..>2435
                     /locus_tag="VXB91_001991"
     CDS             2037..>2435
                     /locus_tag="VXB91_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HEV0471374.1"
                     /translation="MQNLIIGIQKRKNRITLFSSLFLLIIISLSFFILLIGDESYSFS
                     TLIKVLNSETVPGASFSIMEIRLPKLLAGIIAGWSFGLAGFIFQTMLRNPLASPDIIG
                     VTSSSSIAAVFCILVLKTNSLTTGIISITCG"
BASE COUNT          845 a          344 c          425 g          821 t
ORIGIN      
        1 tttaaggagt ttttatgaaa aacaaatttt ttctaatagc tattttagct atgtgtatag
       61 tttttagcgc ttgttcttct aattctgtta aaaatgaaga aaatacttct aaagagcatg
      121 cgcctgataa aatagtttta gatcatgctt tcggtcaaac tatattagat aaaaaacctg
      181 aaagagttgc aactattgct tggggaaatc atgatgtagc attagcttta ggaatagttc
      241 ctgttggatt ttcaaaagca aattacggtg taagtgctga taaaggagtt ttaccatgga
      301 cagaagaaaa aatcaaagaa ctaaatggta aagctaacct atttgacgat ttggatggac
      361 ttaactttga agcaatatca aattctaaac cagatgttat cttagcaggt tattctggta
      421 taactaaaga agattatgac actctatcaa aaattgctcc tgtagcagca tacaaatcta
      481 aaccttggca aactttatgg agagatatga ttaaaattga ttcaaaagcc ttaggtatgg
      541 aaaaagaagg tgatgagtta atcaaaaata ctgaagctcg tatatccaaa gaattagaaa
      601 aacatccaga aatcaaagga aaaatcaaag gaaaaaaagt attatttact atgattaatg
      661 ctgcagatac atcaaaattc tggatttata ctagcaaaga tccaagagca aattatttaa
      721 cagatttagg tctagttttc cctgaatcat taaaagaatt tgagagtgaa gatagttttg
      781 caaaggaaat ttctgcagaa gaagcaaata agataaatga tgctgatgta atcataactt
      841 atggtgatga taaaactctt gaagctttac aaaaagatcc tcttttaggt aaaataaatg
      901 caattaaaaa tggtgccgtt gctgtaattc cagataatac accgttagca gcctcatgca
      961 ctccaacacc actttcaata aactatacta ttgaagaata cctaaatctt ttaggaaatg
     1021 catgcaaaaa tgcgaaataa aaaacaaata aacctaggca taatttttgt aatctgccta
     1081 ggtcttctta ttacaatatt tttgtcatta aagcttggaa caaaagaaat taatatcaga
     1141 gattttttag cagcttttgg aatgggcaat acaaatgatg attttattaa atcaattata
     1201 tataaaagaa tacctagaac tatttttgca attttagcag gttctagtct tgccataagc
     1261 ggtgtattga tgcaatcagt tactagaaac ccaatagctg atccaggtat actcggtata
     1321 aacacaggag caagtcttag tgtagtaatt ggtctttctt ttttaggaat ttcatcaagc
     1381 ataagccata taagttttgc aatcattggt ggcttagtaa gtgcaatttt tgtatacgcg
     1441 attgctgtaa gcggaaaagc aggccttacc cctataaaac ttgccttatc aggaacttgt
     1501 gttagtatgg ctttaagcag ttttgtaagt tttttaattt taccgaataa taacgtctta
     1561 gacaaattta gattttggca aataggtagc cttggagcag ctacattatc ttctatatct
     1621 acactactac cttttataat tttaggtcac ttgatagcta tatttatttc atcagattta
     1681 aacgctttag ctatgggtga tgaaatggct gttggtcttg gagttaatgt taataggata
     1741 agatcacttg caataattgc aagtgtgctt ttatgttcaa gtattactgc aattggtgga
     1801 cctattggct tcgtaggtct tatagttcct cacttttgtg gcttatttat aagcaaagat
     1861 atacgcacaa tgaccatttc ttcatctttt ataggtgcag agctcttgct tatatgtgat
     1921 ataatcggcc gtatgttagg taaaccaggt gaaattgaag tagggataat tactgcaata
     1981 atcgggggtc cagtacttat ttatgtaact atgaaaaata gaggggttaa taactaatgc
     2041 aaaatttaat tataggtatt caaaaaagaa aaaatagaat aacactattt tcctcactat
     2101 ttttattaat aataatcagt ctatcatttt tcattttact tatcggagat gaaagttatt
     2161 ctttttcaac tttgattaaa gtcttaaata gtgaaactgt tcctggagct agtttttcga
     2221 ttatggaaat tagattacca aaattattag caggaattat agctggctgg tcttttggat
     2281 tggcaggatt tatctttcaa actatgttaa gaaatcctct tgcaagtcct gatataatcg
     2341 gtgtcacaag ttcttcatct attgcagcgg tcttttgcat attggtatta aaaacaaata
     2401 gtttaactac tggaattatt tcaataactt gtgga
//
LOCUS       DAVLBE010000106         2268 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.106, whole genome shotgun sequence.
ACCESSION   DAVLBE010000106 DAVLBE010000000
VERSION     DAVLBE010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2268)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2268)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2268
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.106"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(<1..1144)
                     /locus_tag="VXB91_001992"
     CDS             complement(<1..1144)
                     /locus_tag="VXB91_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element IS1167A family transposase"
                     /protein_id="HEV0471375.1"
                     /translation="MEQLHFITKLLDIKDPNIKILDIINMDTHKEIIAKLDYEAPSCP
                     DCGSLMKKYDFQKPSKIPYLETTGMPSRILLRKRRFKCYHCSKMMVAETPLVKKNHQI
                     PRIINQKIAQKLIEKISMTDIAHQLAISTSTVIRKLNDFHFEHDFSRLPKIMSWDEYA
                     FTKGKMSFIAQDFDNLNIITVLEGRTQAVIRNHFLRYDRAVRCQVKIITMDMFSPYYD
                     LAKQLFPCAKIVLDRFHIIQHLSRAMSRFRVQIMNQFERKSHEYKAIKRYWKLIQQDS
                     RKLSDKRFYRPTFRMHLTNKEILDKILSYSEDLKHHYQIYQLLLFHFQNKDPEKFFGL
                     IEDNLKQVHPIFQTVFKTFLKNKEKIVNALQLPYSNAKLEATNNLIK"
     gene            1507..2106
                     /locus_tag="VXB91_001993"
     CDS             1507..2106
                     /locus_tag="VXB91_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0471376.1"
                     /translation="MQILCYFTITVVAKPNNSGEVHLDVSIEDNQGGSGHNFSSVSSS
                     SQTAKYEETGYNNNLSLYTTIDKTSDATALLKLKLNNVDNQPATEVLSSGITVKLNAK
                     DNAGNWTSASNKKEITVKIVSAKPTYPDKILVKNPDNIKDTEKNAIIEKLKEANKNYP
                     VGAPTFAKGEGEHANDIVATYSDGTTYYVPLNDVTKYAR"
BASE COUNT          743 a          345 c          459 g          721 t
ORIGIN      
        1 gtttgatgag attattggtc gcttccaatt tggcgtttga atagggtagt tgaagggcgt
       61 tgacgatttt ctctttgttc tttagaaagg ttttaaagac agtctgaaaa ataggatgaa
      121 cctgcttcag attgtcctca atgagtccga aaaatttctc agggtctttg ttctgaaagt
      181 gaaaaagtaa gagttgatag atctgatagt ggtgtttcaa gtcttctgaa tagcttaaaa
      241 tcttgtcaag aatttcttta tttgttaagt gcatgcgaaa agtagggcga taaaaacgtt
      301 tatcgctgag tttacgacta tcctgttgga tgagtttcca gtaacgcttg atagccttgt
      361 attcatgaga ttttcgttca aactgattca taatttgaac acgaaaacga ctcatggcac
      421 ggctgagatg ttggataata tggaaacgat ctagaacgat tttagcacac ggaaaaagct
      481 gtttagccaa gtcatagtaa ggactaaaca tatccatcgt aatgattttc acttgacaac
      541 gaacggctct atcgtagcga agaaagtgat ttcggatgac agcttgtgtt ctgccttcaa
      601 gaacagtgat aatattaaga ttatcaaaat cttgcgcaat gaaactcatc tttcccttag
      661 tgaaggcata ctcatcccaa gacataatct ttggaagccg agaaaaatca tgctcaaagt
      721 gaaagtcatt gagcttgcga atgacagttg aagttgaaat ggccagctga tgggcaatat
      781 cagtcataga aattttttca attaactttt gagcaatttt ttggttgatg atacgaggga
      841 tttggtgatt tttctttacc aggggagtct cagcaaccat catttttgaa cagtgatagc
      901 acttgaaacg gcgttttcta aggagaattc tagaaggcat accagttgtt tcgaggtaag
      961 ggatcttaga cggtttttga aagtcatatt tcttcattag acttccacaa tcagggcaag
     1021 atggagcctc ataatccagc ttagcgataa tttctttgtg ggtatccata ttgatgatat
     1081 ctagaatctt gatgtttggg tctttaatat cgagcagttt tgtgataaaa tgtaattgtt
     1141 ccatatgatt ctttctaatg agttgttttg tcgcttttca ttataggtca tatgggactt
     1201 tttttctaca caaaaataag ctccataata tccatagggg atttacccac tacaaatatt
     1261 atagagccgt taatatttgg agaagaggat ggccatcttc tccattttta tgtgcagagt
     1321 tatagtgact tgatgctggg aaagtacact gtgactgcta atactcaatg aaaatcaaag
     1381 tgcaaactag gaagctagcc gcaggctgta cttgagtacg tcaaggtgaa gctgacgtgg
     1441 tttgaatttg attttcgaag agtataaaac attcctagaa gttgctttga tttccctaat
     1501 ctatttatgc aaattttatg ttattttact ataacagttg ttgctaagcc aaataatagt
     1561 ggggaagttc atttagacgt aagcattgaa gataatcagg gaggtagtgg gcataatttc
     1621 agttctgttt caagtagctc acaaacagct aaatatgaag aaactggtta taataacaat
     1681 ttatcattat atacaacgat tgataaaacg tctgatgcaa cagctctttt gaaattaaag
     1741 ttgaataatg ttgataatca acctgctact gaagttctta gttcaggaat tactgtaaaa
     1801 ttaaatgcta aagataatgc tggaaactgg acaagtgctt cgaataaaaa agaaataaca
     1861 gtaaaaattg tttctgctaa accgacatat ccagacaaaa tcttagtgaa aaatcctgat
     1921 aatataaaag atacagaaaa aaatgccatt attgaaaaat tgaaagaggc aaataaaaat
     1981 tatccagtag gagctccaac ctttgctaaa ggtgaaggag agcatgcaaa tgatattgta
     2041 gcaacttatt cagatggtac aacttattat gtaccgttaa atgatgtgac aaaatatgcg
     2101 aggtagtggc tgtaccactc acttattcac ctccccgtga tttgtagtag tgataggctt
     2161 tctaactatt attataaaac aaaataaaga gcacaacact ttttcattct gtgttgtgcc
     2221 ttgagtgaaa cgaaaggaat gaattataaa tatgaaaagt atagtcac
//
LOCUS       DAVLBE010000107         2193 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.107, whole genome shotgun sequence.
ACCESSION   DAVLBE010000107 DAVLBE010000000
VERSION     DAVLBE010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2193)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2193)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2193
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.107"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            129..1622
                     /locus_tag="VXB91_001994"
     CDS             129..1622
                     /locus_tag="VXB91_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEV0471377.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAVIVPD
                     GVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGGTDKV
                     WFYDMKADGLSLDDKRQPISDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEND
                     YDLSINKYKEIEYEKVEYEPTEVILKKINDLEKEIQAGLAELEKLLK"
     gene            1635..>2193
                     /locus_tag="VXB91_001995"
     CDS             1635..>2193
                     /locus_tag="VXB91_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV0471378.1"
                     /translation="MKKVKLGEVLSLKKGKKATVLAEQTTLSQRYIQIDDLRNNNNLK
                     FTESLNMTEALPDDILIAWDGANAGTVGYGLSGAVGSTITVLKKNERYKEKIISDYLG
                     VFLESKSQYLREHSTGATIPHLNKNILLDLQLELLGIEEQENIICILNTIKGLITKRK
                     LQLDELNLLVKSRFNEMFGDPLNNNK"
BASE COUNT          774 a          330 c          435 g          654 t
ORIGIN      
        1 gtttgaagag attttcgaag agtataaaat attcaggtga cgcatagata tagttaattg
       61 aagctttgtt tgaaatctga taaaataatg atattactaa gttttaaaaa ctaaagaaaa
      121 gggaagatat gattacaggc gaattaaaaa ataaaatcga tcagctgtgg gaaattcttt
      181 ggacagaagg aaacgcaaat cctttaacaa atattgaaca gttgacttat ctcttattta
      241 tgaaagattt ggatagtgtc gagcttggac gtgaaagtga tgctgaattt ctagggattc
      301 cttatgaggg agtttttcca aaagataaac ctgaataccg ttggtcaact tttaaaaata
      361 taggagatgc tcaggaagtt tatcgtttaa tgactcagga gatttttccg tttattaaaa
      421 atctcaaggg ggatacagat gatacagcct tttcacgata tatgcgagaa gctatttttc
      481 aaataaataa acctgctacg cttcaaaagg caatttctat cttagatgtt tttccaacta
      541 ggggattaga tgtagatttt gataatgaca aacaaagtat tactgatatc ggagatatct
      601 atgaatatct gttatcaaaa ttgtcgaccg caggtaaaaa tggacagttc cgtacacctc
      661 gtcacatcat cgatatgatg gttgagttga tgcaaccgac tatcaaagat atcatctcag
      721 atcccgctat gggttctgct ggcttcttag tatctgctag ccgttactta aagcgtaaga
      781 aagatgaatg ggaaaccaat acagataata tcaatcattt tcataatcag atgtttcatg
      841 gaaatgatac ggatacgact atgttgagac ttggggcgat gaacatgatg ctacatggag
      901 tagaaaatcc acaaatcagt taccttgact cgctgtctca agataatgaa gaagccgata
      961 aatatacttt ggttttagca aatcctcctt ttaagggctc acttgactac aattcaacct
     1021 ctaatgacct tcttgcaacc gtaaaaacca aaaaaacaga attactcttt ctttctcttt
     1081 tcttgcgaac tttaaaacca ggtggacgag cagcagttat cgtacctgat ggtgtccttt
     1141 ttggttcgtc taaagctcat aaaggaattc gtcaggaaat tgtagagaat cataagcttg
     1201 atgctgtaat ctcaatgcct agtggtgtgt tcaagcctta tgctggagtt tcaactgcca
     1261 ttctcatctt tacaaaaact ggtaatggtg gtactgacaa agtctggttt tacgatatga
     1321 aagcggatgg tttaagtttg gatgataagc gacaaccgat tagcgacaat gatattccag
     1381 atattatcga acgctttcat catcttgaaa aagaagcaga acgtcagaga acggatcaat
     1441 ctttctttgt tccagttgct gagataaagg aaaatgatta tgatttgtct atcaataaat
     1501 ataaagagat tgagtatgaa aaagttgagt atgaaccaac agaggtcatc ttaaagaaaa
     1561 tcaatgattt agaaaaagaa attcaagctg gcttggctga attagaaaaa ttactcaagt
     1621 agggaggtgg ctgtatgaaa aaagtgaagt tgggggaagt cttatctcta aaaaaaggca
     1681 agaaagccac tgtacttgct gaacaaacaa ctctaagcca acgttatatt caaatagatg
     1741 atttaagaaa taataataat ttaaaattca ctgaaagttt aaatatgact gaagcactcc
     1801 cagatgatat tctgatagca tgggatggag ctaatgcagg aacagttggt tatggattat
     1861 cgggagctgt tggtagtaca attacggtct taaaaaagaa tgagcgatac aaagaaaaaa
     1921 ttatatcaga ttacttggga gtctttttgg aaagtaaatc gcagtattta cgagaacatt
     1981 caacaggtgc aacaattcct catttaaaca agaatatatt acttgattta caattagaat
     2041 tgctaggtat cgaagaacaa gagaacatta tctgtattct taatacgatt aaagggctta
     2101 ttactaaaag aaaattgcag ttagatgaac taaacttgct cgtcaaatcc cgatttaacg
     2161 agatgtttgg ggatccttta aataataaca aga
//
LOCUS       DAVLBE010000108         1826 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.108, whole genome shotgun sequence.
ACCESSION   DAVLBE010000108 DAVLBE010000000
VERSION     DAVLBE010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1826)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1826)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1826
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.108"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            <1..573
                     /locus_tag="VXB91_001996"
     CDS             <1..573
                     /locus_tag="VXB91_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV0471379.1"
                     /translation="KDGFSAARLIILGIGFQAVTRAGTSFLLLKVARYELQEVMRWLS
                     GSLSFTKLDDIPLVLIVSIIATILVLFFNKRLEIIELGEEIAIGLGANPELSRLVLIF
                     CAVSLTAFSTSITGPIACISFLAGPIALNIGKKRSPILAGLVGILLVLLSDIFSQNIL
                     PARYPVGVVTGLLGSPYLIYLLIKMNRRNI"
     gene            573..1367
                     /locus_tag="VXB91_001997"
     CDS             573..1367
                     /locus_tag="VXB91_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0471380.1"
                     /translation="MKGLWSNNLTCGYDEKIILENINIKIPEEKISVIIGSNGCGKST
                     LIKTLSRLIKPLEGEVLLDNKSINSYKEKDLAKHIAILPQSPIIPESITVADLVSRGR
                     FPYRKPFKSLGKDDLEIINRSMVKANVEDLANNLVEELSGGQRQRVWIALALAQDTSI
                     LLLDEPTTYLDISYQIELLDLLTDLNQKYKTTICMILHDINLTARYADYLFAIKEGKL
                     VAEGKPEDILNDKLVKDIFNLEAKIIRDPISNSPLMIPIGKHHVNS"
BASE COUNT          698 a          281 c          303 g          544 t
ORIGIN      
        1 aaagatggtt tttcagcagc aagactgata atattaggta ttggttttca agctgtcaca
       61 agagcaggca cctcattttt attgttgaaa gtagcaagat atgaattaca agaagttatg
      121 agatggctca gtggctcttt atcttttaca aagttagatg acatacctct tgttctaata
      181 gtaagtatta ttgctactat attagtttta ttttttaata aaagactaga aattattgaa
      241 cttggtgaag aaatagcaat cggacttgga gcaaatcccg agctttcaag gcttgtttta
      301 attttttgcg ctgtatcttt aactgctttt tctacttcaa ttacaggacc aatagcttgt
      361 atatcttttt tagctggtcc catagcctta aatattggca agaaaagaag cccaatatta
      421 gctggattgg ttggaatttt actagttttg ttatcagaca tattctctca aaatatttta
      481 ccagctagat atccagtagg tgttgtaact ggcttgttag gttcaccata cttaatatac
      541 ttactaataa aaatgaacag gaggaatata taatgaaagg tctgtggtca aataatctta
      601 cctgcggtta tgatgaaaaa ataatcttgg aaaatataaa tataaaaata cctgaagaaa
      661 aaatatcagt tattattggg tcaaatggtt gtgggaaatc aacactcatt aaaaccttgt
      721 ctcgacttat aaagccatta gagggagaag tattgcttga taataaatca attaattctt
      781 ataaagaaaa agatttagca aaacacatag ctatattacc tcaatctcca ataatccctg
      841 aatcaataac agtagctgat cttgtaagcc gtggtcgttt cccctacaga aagcctttta
      901 agagtcttgg aaaagatgac cttgaaataa taaacagatc aatggttaag gccaatgttg
      961 aagatctagc aaataaccta gttgaagaac tttctggggg tcaaaggcaa agagtatgga
     1021 tagctctagc cctagcccaa gatacaagta tcctactttt agatgagcca actacttact
     1081 tggatatctc atatcaaata gaactattag acctcttgac tgatctaaac caaaaatata
     1141 agacaaccat ttgcatgatt ttgcacgata taaatctaac agcaagatac gctgattacc
     1201 tatttgcaat taaagaaggt aaacttgttg cagagggaaa gcctgaagat atactaaatg
     1261 ataaactagt taaagatatc tttaatcttg aagcaaaaat tatacgtgac cctatttcca
     1321 attcgcctct aatgattcct attggcaagc accatgttaa ctcttaataa ttgaatattg
     1381 gaattcattt aaaagtcgca aattttgaac tgaccctcaa aagttaggcc aaaaaactaa
     1441 ctaaaggagg tcagtttttt aatggcaaat acagcacaga atttaagata aaattagtaa
     1501 aagaatatca tgaatgaaaa ataggatata gagaataaca gcaatattaa aaagatcagg
     1561 actgataata aacaaaaaga aagtacaacg actagttcaa aagctaaaac ttcaagtaaa
     1621 aagttattca agaaaatcta gaaaatactc atcctacaaa ggacaggtag gaaaaatatc
     1681 agacaacaaa ataaaaagaa atatttatta ccgaaaaaaa ggggaaatcg agttaagtac
     1741 caacaggctc atctattcca aaaagatatt tactcgatgg aaaaactcct agaattagtg
     1801 ctacaaatat tgacaatggt atctta
//
LOCUS       DAVLBE010000109         1661 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.109, whole genome shotgun sequence.
ACCESSION   DAVLBE010000109 DAVLBE010000000
VERSION     DAVLBE010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1661)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1661)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1661
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.109"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            145..1491
                     /locus_tag="VXB91_001998"
     CDS             145..1491
                     /locus_tag="VXB91_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element ISSpn5 family transposase"
                     /protein_id="HEV0471381.1"
                     /translation="MNSLPNHHFQNKSFYQLSFDGGHLTQYGGLIFFQELFSQLKLKE
                     RISKYLVTNDQRRYCRYSDSDILVQFLFQLLTGYGTDYACKELSADAYFPKLLEGGQL
                     ASQPTLSRFLSRTDEETVHSLRCLNLELVEFFLQFHQLNQLIVDIDSTHFTTYGKQEG
                     VAYNAHYRAHGYHPLYAFEGKTGYCFNAQLRPGNRYCSEEADSFITPVLERFNQLLFR
                     MDSGFATPKLYDLIEKTGQYYLIKLKKNTVLSRLGDLSLPCPQDEDLTILPHSAYSET
                     LYQAGSWSHKRRVCQFSERKEGNLFYDVISLVTNMTSGTSQDQFQLYRGRGQAENFIK
                     EMKEGFFGDKTDSSTLIKNEVRMMMSCIAYNLYLFLKHLAGGDFQTLTIKRFRHLFLH
                     VVGKCVRTGRKQLLKLSSLYAYSELFSALYSRIRKVNLNLPVPYEPPRRKASLMMH"
BASE COUNT          491 a          359 c          325 g          486 t
ORIGIN      
        1 ctaaaaacca tccagaatcc ttgccttagc ttagatcctg gatggtttct tttttcaccc
       61 aatgggtgtt ttttactaga caaaaaagag tttccccttt atggtataag tgtagaaaaa
      121 aacacaaaaa gaaaggaaac tcacatgaac agtttaccaa atcatcactt ccaaaacaag
      181 tctttttacc aactatcttt cgatggaggt catttaaccc agtatggtgg tcttatcttt
      241 tttcaggaac ttttttccca gctgaaacta aaagagcgga tttctaagta tttagtaacg
      301 aatgaccaac gccgctactg tcgttattcg gattcagata tccttgtcca gttcctcttt
      361 caactgttaa caggttatgg aacggactat gcttgtaaag aattgtcagc tgatgcctac
      421 tttccaaaat tattggaagg agggcagctt gcttcacagc caaccttatc ccgttttctt
      481 tccagaactg acgaggaaac agtccatagt ttgcgatgcc tcaaccttga attggtcgaa
      541 ttctttttac agtttcacca gctaaaccaa ctcattgtag atatcgattc tacccatttc
      601 acaacttatg gcaagcaaga aggtgttgct tataacgccc actatcgtgc tcatggctat
      661 catcctcttt atgctttcga ggggaagaca ggttattgtt tcaatgccca gcttcgtcct
      721 ggtaatcgtt attgttctga agaggcagac agctttatca cacctgtttt agaacggttt
      781 aatcaacttc tctttcgaat ggatagtggc tttgcgaccc caaaattata cgatttaatt
      841 gaaaaaacag ggcaatacta cctcataaaa ctcaagaaaa atactgttct gagccgtctt
      901 ggagaccttt ccctcccttg cccacaggat gaggacttaa ccatcttgcc ccactccgcc
      961 tactcagaaa ctctctatca agcaggatct tggtcgcaca agcgtcgtgt ctgccagttc
     1021 tctgaacgaa aagaaggaaa cttgttctac gatgttattt ctctcgttac aaatatgacg
     1081 agtggaacaa gccaagacca gtttcagctt tatcgtggac gtggtcaagc cgagaatttc
     1141 atcaaggaga tgaaggaggg attttttggc gataaaacgg atagttcaac cttaatcaaa
     1201 aacgaagttc gtatgatgat gagctgtatc gcctacaatc tctatctttt tctcaaacat
     1261 ctagctggag gtgacttcca aactttaaca atcaaacgct tccgccatct ttttcttcac
     1321 gtggtaggaa aatgtgttcg aacaggacgc aagcagctcc tcaaattgtc tagtctctat
     1381 gcctattccg aattgttttc agcactttat tctaggatta gaaaagtcaa cctgaatctt
     1441 cctgttcctt atgaaccacc tagaagaaaa gcgtcgttaa tgatgcatta aagaacagtc
     1501 gagatgaaaa aatcgtgtga cgaaccaagg gaggagtctg cccttttgag gaaatctagc
     1561 gaggaaaaac gatactggaa cagcagaaag taaaactgac ctcatgagga ggaagaaagt
     1621 ggctcatgag gtcaggggtt ttgtaagtta catctagttg a
//
LOCUS       DAVLBE010000110         1545 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.110, whole genome shotgun sequence.
ACCESSION   DAVLBE010000110 DAVLBE010000000
VERSION     DAVLBE010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1545)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1545)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1545
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.110"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            27..1373
                     /gene="gdhA"
                     /locus_tag="VXB91_001999"
     CDS             27..1373
                     /gene="gdhA"
                     /locus_tag="VXB91_001999"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HEV0471382.1"
                     /translation="MTSAKEYIQSVFETVKARNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVVSFRVPWVDRDGKIQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHEGTVWTYAGNYDIALPCATQNEINGEAAKR
                     LVAQGVICVSEGANMPSDLDAIKVYKENGIFYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDGRLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGIV"
BASE COUNT          479 a          298 c          324 g          444 t
ORIGIN      
        1 aaatatgaca ataaaaggag aacgatatga catctgctaa agaatatatc caaagcgtgt
       61 ttgaaactgt gaaagctcgt aacgggcacg aggctgaatt cctccaagct gttgaagaat
      121 ttttcaacac tttagaacct gtatttgaaa aacaccctga gtatatcgaa gaaaatatct
      181 tggcacgtat tactgagcct gagcgcgtgg tttctttccg tgttccttgg gttgaccgtg
      241 atggaaaaat tcaagtaaac cgtggttacc gtgttcaatt caactcagct gttggaccat
      301 acaaaggtgg acttcgtttc cacccaactg taaaccaagg gatcttgaaa ttcctcggat
      361 ttgaacaaat ctttaaaaat gtcttgactg gacttcctat cggtggaggt aaaggtggat
      421 cagacttcga tcctaaaggt aaaacagatg ctgaagtgat gcgcttctgc caaagcttca
      481 tgactgaatt gcaaaaacac atcggaccat cacttgacgt acctgctggt gatatcggtg
      541 ttggtggacg tgaaattggt tacctttacg gtcaatacaa acgtcttaac caatttgatg
      601 ctggtgtctt gactggtaaa cctcttggat ttggtggtag cttgattcgt ccagaagcaa
      661 ctggttacgg tttggtttac tatactgaag aaatgctcaa agctaacggt aacagctttg
      721 ctggtaagaa agtcgttatt tcaggttctg gtaacgttgc tcaatatgct cttcaaaaag
      781 caactgaact cggtgcaact gttatttctg tttctgactc aaatggttat gtcatcgatg
      841 aaaatggtat cgacttcgat cttttggttg atgttaaaga aaaacgtcgt gctcgtttga
      901 ctgagtatgc agctgaaaaa gcaactgcaa cctaccacga aggtactgta tggacttacg
      961 ctggaaacta tgacattgct cttccatgtg ccactcaaaa cgaaatcaac ggtgaagcag
     1021 ctaaacgttt ggttgctcaa ggcgttatct gtgtatctga aggtgccaac atgccgagcg
     1081 accttgatgc catcaaagtt tacaaagaaa atggtatctt ctacggacct gcaaaagctg
     1141 ccaacgctgg tggtgtagcc gtttcagctc ttgaaatgag ccaaaacagt cttcgcctct
     1201 catggactcg tgaagaagtt gatggccgtc tcaaagacat catgacaaac atcttcaaca
     1261 cagctaaaac gacttcagaa acatacggtc ttgataaaga ctaccttgca ggagctaaca
     1321 ttgctgcctt tgaaaatgta gcaaatgcca tgattgcaca aggtattgtt taagatttat
     1381 ttactcaatc ctcaatcact acgattgggg atttttagct tgaattaaaa aattggaaaa
     1441 tctaattaaa taaaatgaaa tgaaatgaaa taaaaactga acaaattgat tgcggaattc
     1501 aaaccaattt ctaacatatt tctagaaatt aatttgactt ttcta
//
LOCUS       DAVLBE010000111         1494 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.111, whole genome shotgun sequence.
ACCESSION   DAVLBE010000111 DAVLBE010000000
VERSION     DAVLBE010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1494)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1494)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1494
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.111"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(68..155)
                     /locus_tag="VXB91_002000"
     tRNA            complement(68..155)
                     /locus_tag="VXB91_002000"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(119..121),aa:Ser,seq:gct)
     gene            complement(162..235)
                     /locus_tag="VXB91_002001"
     tRNA            complement(162..235)
                     /locus_tag="VXB91_002001"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(199..201),aa:Ile,seq:gat)
     gene            complement(271..341)
                     /locus_tag="VXB91_002002"
     tRNA            complement(271..341)
                     /locus_tag="VXB91_002002"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(307..309),aa:Gly,seq:tcc)
     gene            complement(361..433)
                     /locus_tag="VXB91_002003"
     tRNA            complement(361..433)
                     /locus_tag="VXB91_002003"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(398..400),aa:Phe,seq:gaa)
     gene            complement(437..510)
                     /locus_tag="VXB91_002004"
     tRNA            complement(437..510)
                     /locus_tag="VXB91_002004"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(474..476),aa:Met,seq:cat)
     gene            complement(521..610)
                     /locus_tag="VXB91_002005"
     tRNA            complement(521..610)
                     /locus_tag="VXB91_002005"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(572..574),aa:Ser,seq:tga)
     gene            complement(621..694)
                     /locus_tag="VXB91_002006"
     tRNA            complement(621..694)
                     /locus_tag="VXB91_002006"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(658..660),aa:Ile,seq:cat)
     gene            complement(708..781)
                     /locus_tag="VXB91_002007"
     tRNA            complement(708..781)
                     /locus_tag="VXB91_002007"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(745..747),aa:Met,seq:cat)
     gene            complement(787..860)
                     /locus_tag="VXB91_002008"
     tRNA            complement(787..860)
                     /locus_tag="VXB91_002008"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(824..826),aa:Pro,seq:tgg)
     gene            complement(876..949)
                     /locus_tag="VXB91_002009"
     tRNA            complement(876..949)
                     /locus_tag="VXB91_002009"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(913..915),aa:Arg,seq:acg)
     gene            complement(959..1044)
                     /locus_tag="VXB91_002010"
     tRNA            complement(959..1044)
                     /locus_tag="VXB91_002010"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1008..1010),aa:Leu,seq:taa)
     gene            complement(1052..1123)
                     /locus_tag="VXB91_002011"
     tRNA            complement(1052..1123)
                     /locus_tag="VXB91_002011"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1089..1091),aa:Gly,seq:gcc)
     gene            complement(1146..1218)
                     /locus_tag="VXB91_002012"
     tRNA            complement(1146..1218)
                     /locus_tag="VXB91_002012"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1183..1185),aa:Thr,seq:tgt)
     gene            complement(1237..1318)
                     /locus_tag="VXB91_002013"
     tRNA            complement(1237..1318)
                     /locus_tag="VXB91_002013"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1282..1284),aa:Leu,seq:tag)
     gene            complement(1324..1396)
                     /locus_tag="VXB91_002014"
     tRNA            complement(1324..1396)
                     /locus_tag="VXB91_002014"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1361..1363),aa:Lys,seq:ttt)
     gene            complement(1421..1493)
                     /locus_tag="VXB91_002015"
     tRNA            complement(1421..1493)
                     /locus_tag="VXB91_002015"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1458..1460),aa:Asp,seq:gtc)
BASE COUNT          412 a          419 c          330 g          333 t
ORIGIN      
        1 aagtttacgg atctgaagtt ttattgtctc taaaaacaaa aaagagagtt acaaactctc
       61 attaaaacgg agaataaggg attcgaaccc ttgcgccagt tacccgacct aacgatttag
      121 caaaccgtcc tcttcagcct cttgagtaat tctccaatta atgggcacga gtggactcga
      181 accaccgacc tcacgcttat caggcgtgcg ctctaaccac ctgagctacg cgcccaagtt
      241 aaaaaacttg gtaatttgaa caaagttcaa agcgggtgac gagaatcgaa ctcgcgacaa
      301 cagcttggaa ggctgtagtt ttaccactaa actacacccg cataaatact atcaataaaa
      361 tggcgcgaga cggaatcgaa ccgccgacac atggagcttc aatccattgc tctaccaact
      421 gagctaccga gccttattgc gggagcagga tttgaaccta cgaccttcgg gttatgagcc
      481 cgacgagcta ccgagctgct ccatcccgcg ttaatataaa aggaggatgt gggattcgaa
      541 cccacgcacg cttttacacg cctgacggtt ttcaagaccg ttcccttcag ccggacttgg
      601 gtaatcctcc aatattcaaa tggaccttgt aggacttgaa cctacgacca ctcggttatg
      661 agccgagagc tctaaccagc tgagctaaag gtccgacaag atcattatag cggcgaaggg
      721 gatcgaaccc ccgacctccc gggtatgaac cggacgctct agccagctga gctacaccgc
      781 catgaatcgg gaagacagga ttcgaacctg cgacaccttg gtcccaaacc aagtactcta
      841 ccaagctgag ctacttcccg agttaaatag aaaaatgcac cctagaggag tcgaacctct
      901 aaccgcctga ttcgtagtca ggtactctat ccagttgagc taagggtgct ccatattatg
      961 ccgaggaccg gaatcgaacc ggtacgatcg ttaccaatcg caggatttta agtcctgtgc
     1021 gtctgccagt tccgccaccc cggcctctct aagcgaacga cgggattcga acccgcgacc
     1081 cccaccttgg caaggtggtg ttctaccact gaactacgtt cgcactgttt tcttctatct
     1141 aaaaatgccg gctacatgac ttgaacacgc gaccctctga ttacaaatca gatgctctac
     1201 caactgagct aagccggctc atttgttata tcttaatgcg ggttaaggga cttgaacccc
     1261 cacgccgtta agcgccagat cctaaatctg gtgcgtctgc caattccgcc aaacccgcat
     1321 atatgacccg tactgggctc gaaccagtga cccattgatt aaaagtcaat tgctctacca
     1381 actgagctaa cgagtctaaa ataacttgcg ttaccttaaa cggtcccgac gggaatcgaa
     1441 cccgcgatct tcgccgtgac agggcgacgt gataaccgct acactacggg acct
//
LOCUS       DAVLBE010000112         1451 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.112, whole genome shotgun sequence.
ACCESSION   DAVLBE010000112 DAVLBE010000000
VERSION     DAVLBE010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1451)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1451)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1451
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.112"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            11..>1451
                     /gene="pcpA"
                     /locus_tag="VXB91_002016"
     CDS             11..>1451
                     /gene="pcpA"
                     /locus_tag="VXB91_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein PcpA"
                     /protein_id="HEV0471383.1"
                     /translation="MKKTTILSLTTAAVILAAYVPNEPILADTPSSEVIKETKVGSII
                     QQNNIKYKVLTVEGNIGTVQVGNGVTPVEFEAGQDGKPFTIPTKITVGDKVFTVTEVA
                     SQAFSYYPDETGRIVYYPSSITIPSSIKKIQKKGFHGSKAKTIIFDKGSQLEKIEDRA
                     FDFSELEEIELPASLEYIGTSAFSFSQKLKKLTFSSSSKLELISHEAFANLSNLEKLT
                     LPKSVKTLGSNLFRLTTSLKHVDVEEGNESFASVDGVLFSKDKTQLIYYPSQKNDESY
                     KTPKETKELASYSFNKNSYLKKLELNEGLEKIGTFAFADAIKLEEISLPNSLETIERL
                     AFYGNLELKELILPDNVKNFGKHVMNGLPKLKSLTIGNNINSLPSFFLSGVLDSLKEI
                     HIKNKSTEFSVKKDTFAIPETVKFYVTSEHIKDVLKSNLSTSNDIIVEKVDNIKQETD
                     VAKPKKNSNQGVVGWVKDKGLWYYLNESGS"
BASE COUNT          566 a          200 c          236 g          449 t
ORIGIN      
        1 ggaaatttaa atgaaaaaaa ctacaatatt atcattaact acagctgcag ttattttagc
       61 agcatatgtc cctaatgaac caatcctagc agatactcct agttcggaag taatcaaaga
      121 gactaaagtt ggaagtatta ttcaacaaaa taatatcaaa tataaggttc taactgtaga
      181 aggtaacata ggcactgttc aagtgggtaa tggagttact cctgtagagt ttgaagctgg
      241 tcaagatgga aaaccattca cgattcctac aaaaatcaca gtaggtgata aagtatttac
      301 cgttactgaa gtagctagtc aagcttttag ttattatcca gatgaaacag gtagaattgt
      361 ctactatcct agctctatta ctatcccatc aagcataaaa aaaatacaaa aaaaaggctt
      421 ccatggaagt aaagctaaaa ctattatttt tgacaaaggt agtcagctgg agaaaattga
      481 agatagagct tttgattttt ctgaattaga agagattgaa ttgcctgcat ctctagaata
      541 tattggaaca agtgcatttt cttttagtca aaaattgaaa aagctaacct tttcctcaag
      601 ttcaaaatta gaattaatat cacatgaggc ttttgctaat ttatcaaatt tagagaaact
      661 aacattacca aaatcggtta aaacattagg aagtaatcta tttagactca ctactagctt
      721 aaaacatgtt gatgttgaag aaggaaatga atcgtttgcc tcagttgatg gtgttttgtt
      781 ttcaaaagat aaaacccaat taatttatta tccaagtcaa aaaaatgacg aaagttataa
      841 aacgcctaag gagacaaaag aacttgcatc atattcgttt aataaaaatt cttacttgaa
      901 aaaactcgaa ttgaatgaag gtttagaaaa aattggtact tttgcatttg cagatgcgat
      961 taaacttgaa gaaattagct taccaaatag tttagaaact attgaacgtt tagcctttta
     1021 cggtaattta gaattaaaag aacttatatt accagataat gttaaaaatt ttggtaaaca
     1081 cgttatgaac ggtttaccaa aattaaaaag tttaacaatt ggtaataata tcaactcatt
     1141 gccgtccttc ttcctaagtg gcgtcttaga ttcattaaag gaaattcata ttaagaataa
     1201 aagtacagag ttttctgtga aaaaagatac atttgcaatt cctgaaactg ttaagttcta
     1261 tgtaacatca gaacatataa aagatgttct taaatcaaat ttatctacta gtaatgatat
     1321 cattgttgaa aaagtagata atataaaaca agaaactgat gtagctaaac ctaaaaagaa
     1381 ttctaatcag ggagtagttg gttgggttaa agacaaaggt ttatggtatt acttaaacga
     1441 atcaggttca a
//
LOCUS       DAVLBE010000113         1278 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.113, whole genome shotgun sequence.
ACCESSION   DAVLBE010000113 DAVLBE010000000
VERSION     DAVLBE010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1278)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1278)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1278
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.113"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(37..1277)
                     /locus_tag="VXB91_002017"
     CDS             complement(join(37..938,938..1277))
                     /locus_tag="VXB91_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEV0471384.1"
                     /translation="MVKLIDRYGIEIVKKGKNRHYSSKLKQEMMDKALLEGCSQRSIS
                     LDYALPNQGMLSFWPAQYKKNGYTIVEKTRGRPAKMGRKRKKTWEEMTELERLQEENE
                     RLRTEVAYLKKFKRVRGKGRSPRARKAETVREMVSGGFRLDFLLETARLARSTYYYQL
                     KQLDGVDKDKEIKTEIQGIDNEHKGNYGYRRIHLELRNRGFVVNHKKVQRLMRILGLT
                     ARIRRKRKYSSYQGEIGKKAENLIQRQFEASRPMEKCYTDVTEFAIPNSTQKLYLSPV
                     LDGFNSEIIAYHLSTSPNLEQVKSMLEQAFTEKYYENTILHSDQGWQYQHDSYHRFLE
                     SKGIQASMSRKGNSPDNGMMESFFGILKSEMFYGYEKNFRSLENLEQAIVDYIDYYNN
                     KRIKVKLKGLSSVQYRTKSFG"
BASE COUNT          330 a          283 c          216 g          449 t
ORIGIN      
        1 aatactgtac tgaccccaaa aaattagaca aataatttat ccaaaggatt tagttctgta
       61 ctgcacagaa ctaagtcctt ttagttttac cttaattcgt ttgttgttgt agtaatcaat
      121 gtagtccaca atagcttgtt caaggttttc taaagatcta aagttcttct cataaccata
      181 aaacatctcc gatttcaaaa tgccaaagaa agattccatc atgccgttgt ctgggctgtt
      241 gcccttgcgt gacatggatg cttgaattcc cttactctct aggaaccgat gataagaatc
      301 gtgttggtat tgccagcctt ggtcactatg gagaatcgta ttctcatagt atttctctgt
      361 aaaggcttgt tctaacatac tcttcacttg ttctaagttg ggcgaagtag aaagatgata
      421 agcaatgatt tcactgttaa aaccatctaa aactggtgat aaatagagtt tctgtgtgct
      481 atttggaatg gcaaactctg tcacatctgt atagcacttt tccattggcc tcgatgcttc
      541 gaactggcgt tgaatgagat tctctgcttt cttgccaatc tctccttggt aggaagaata
      601 cttccgttta cggcgaattc gagccgttaa accaagaatt ctcatcaacc gttgaacttt
      661 cttatgattg accacaaaac cacgattcct tagttctaaa tggattcgac gatagccata
      721 gttgccttta tgttcattat caatgccctg aatttcggtt ttaatctctt tatctttatc
      781 aaccccatcc agttgtttca actgataata gtaagtcgag cgagctaaac gtgctgtttc
      841 aagaagaaaa tctagtcgaa atcctcctga aaccatttct ctaactgtct ctgcctttct
      901 cgctctaggg cttcgtccct ttcctctaac tcttttaact tttttaggta ggccacctca
      961 gtccgtaagc gttcattctc ctcctggagt cgttctagtt ctgtcatttc ttcccaagtc
     1021 ttcttccgtt tacgtcccat tttagctggt ctccctcttg ttttctcaac aatagtatac
     1081 ccgtttttct tgtattgtgc cggccaaaat gaaagcattc cttggtttgg gagggcataa
     1141 tcaagactaa tacttctttg tgaacaacct tccagtaagg ctttatccat catttcttgt
     1201 ttcaatttag aagaatagtg acgattcttc ccttttttaa cgatttctat gccataacgg
     1261 tcaattaatt tcaccatg
//
LOCUS       DAVLBE010000114         1121 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.114, whole genome shotgun sequence.
ACCESSION   DAVLBE010000114 DAVLBE010000000
VERSION     DAVLBE010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1121)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1121)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1121
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.114"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            1..806
                     /locus_tag="VXB91_002018"
                     /pseudo
     CDS             1..806
                     /locus_tag="VXB91_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436304.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
     gene            complement(841..>1121)
                     /locus_tag="VXB91_002019"
     CDS             complement(841..>1121)
                     /locus_tag="VXB91_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0471385.1"
                     /translation="TSDFFEAWFQKFLLPTLTTPSVIIMDNARFHRMGKLELLCEEFG
                     HKLLPLPPYSPEYNPIEKTWAYIKKNLKKVLPSCNTFYEALFSCSCFN"
BASE COUNT          371 a          230 c          188 g          332 t
ORIGIN      
        1 aaattcaaac tagaattctt cttagaaaag gccgttttaa gtgctatcat tgctcaaaaa
       61 tggagctcgc tgagacttct atcgtcaaga agaatcatca aattccttgt atcatcaacc
      121 aaaagattgc tcaaaagtta attgaaaaga tttctatgac cgacattgat catcagttgt
      181 ctatttcaac ttcaactgtc attcgcaaga tcaataattt tcactttgag catgattttt
      241 cgcgtcttcc tgagattatg tcctaggacg ttgaaacagt ccggggagtg actgtttcaa
      301 tcgggagatg gagatgagct ttattgctca ggactttgat aaactcaata tcataactgt
      361 tcttgagagc agaacacaag ccatcatccg aaatcccatg aatacaaggc tatcaagcgc
      421 tactggaagc tcattcaaca agatagtcag aaactgagtg ataaacgatt ttatcgccct
      481 acttttcgta tgcacttgac taataaagaa attctagata aacttttgag ctattccgaa
      541 gacttgaaac accactataa tctctatcag ctcttgcttt tccacctctg tttcagactt
      601 tgtttaaaac cttcctcaaa gataaagaga aaatcgtcaa cgcccttcaa ttaccttatt
      661 ccaacgccaa actggaagcc accaataatc tcatcaaact tatcaagcac aatgcctttg
      721 gttttaggaa ctttgaaaac ttcaaaaaag aaaggacgaa atttgtcctt tctagatctt
      781 cgctttcttc aacccactac agttgacaaa gaaccgaaaa atgtctcgcc tctaatatag
      841 tcaattgaaa caagaacaag agaaaagagc ctcgtaaaag gtattgcaac ttggtaatac
      901 ctttttgagg ttctttttga tataagccca tgttttctca ataggattgt actcaggtga
      961 gtagggagga agaggtaaaa gtttatgccc aaactcctcg cataaaagtt ctaacttacc
     1021 cattctatgg aatcttgcat tatccataat aataaccgat ggtgtggtta atgttggtaa
     1081 gagaaacttc tgaaaccaag cttcaaaaaa gtcgctcgtc a
//
LOCUS       DAVLBE010000115         1042 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.115, whole genome shotgun sequence.
ACCESSION   DAVLBE010000115 DAVLBE010000000
VERSION     DAVLBE010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1042)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1042)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1042
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.115"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            1..1042
                     /locus_tag="VXB91_002020"
                     /pseudo
     CDS             1..1042
                     /locus_tag="VXB91_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
BASE COUNT          319 a          229 c          170 g          324 t
ORIGIN      
        1 tggtatgcct actagaattc tccttagaaa gcgtcgattc aagtgttatc actgttcaaa
       61 aatgatggtc gctgaaactt ctatcgtcaa gaagaatcac caaatccctc gtattatcaa
      121 ccaaaaaatt gcgcaaaagt taattgaaaa gatttctatg accgatattg cccatcagct
      181 ttccatctca acttcaactg ttattcgtaa gctcaatgat tttcacttta aacatgattt
      241 ttcttgtctt cctgagatta tgtcttggga tgagtatgct tttacaaagg gaaagatgag
      301 tttcattgcg caagattttg ataatcttaa tattatcact gttcttgaag gcagaacaca
      361 agctgtcatc cgaaatcact ttcttcgcta cgatagagcc gtccgatgtc gcgtcaaaat
      421 cattactatg gatatgttta gcccttacta tgacttggct aaacagcttc gctttcaaat
      481 ttctaggctc aggctgaaac agtctcccag actgtttcac tcccgaatgc taaaatcgtt
      541 cttgatcgct ttcacattgt acaacatctt agccgtgcta tgagtcgtgt gcatgtccaa
      601 atcatgaatc agtttcatcg aaaatcccat gaatacaagg ctatcaagcg ctactggaaa
      661 ctcattcaac aggatagccg taaactgagt gataagcgat tttatcgtcc tacttttcgt
      721 atgcacttaa ccaataaaga gattttaaac aagcttttga gctattcgga agacttgaaa
      781 caccactatc agctctatca gctcttgctt tttcacttcc agaacaagga accagagaaa
      841 tttttcggac ttattgagga caatcttaag caggttcatc ctctttttca gactgtcttt
      901 aaaaccttcc tcaaagataa agaaaagatt gtcaacgccc ttcaactaca ctattctaat
      961 gccaaactgg aagcgaccaa taatctcatc aaacttatca agcgcaatgc ctttggtttt
     1021 cggaactttg aaaacttcaa aa
//
LOCUS       DAVLBE010000116          869 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.116, whole genome shotgun sequence.
ACCESSION   DAVLBE010000116 DAVLBE010000000
VERSION     DAVLBE010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 869)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 869)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..869
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.116"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            <1..>869
                     /locus_tag="VXB91_002021"
     CDS             <1..>869
                     /locus_tag="VXB91_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEV0471386.1"
                     /translation="LDIKDPNIQILDIINKDTHKEIIAKLDYDAPSCPECGSQMKKYD
                     FQKPSKIPYLETTGMPTRILLRKRRFKCYHCSKMMVAETSIVKKNHQIPRIINQKIAQ
                     KLIEKISMTDIAHQLSISTSTVIRKLNDFHFKHDFSRLPEIMSWDEYAFTKGKMSFIA
                     QDFEKLDIITVLEGRTQAIIRNHFLRYDRVVRCRVKIITMDMFSPYYDLARQLFPCAK
                     IVLDRFHIVQHLSRAMSRVRVQIMNQLDRKSHEYKAIKRYWKLIQQDSRKLSDKHFYR
                     PTFRMHLTNKEIF"
BASE COUNT          272 a          182 c          149 g          266 t
ORIGIN      
        1 tactagacat taaagaccct aatatccaga ttttagacat catcaataag gatacacaca
       61 aggaaatcat cgccaaactg gactacgacg ccccatcttg ccctgagtgc ggaagtcaaa
      121 tgaagaaata tgactttcaa aaaccttcta aaattcctta tcttgaaacg actggtatgc
      181 ctactagaat tctccttaga aagcgtcgat tcaagtgcta tcactgttca aaaatgatgg
      241 tcgctgaaac ttctatcgtc aagaagaatc accaaatccc tcgtatcatc aaccaaaaga
      301 ttgctcaaaa gttaattgaa aagatttcta tgactgatat tgcccatcag ctttccatct
      361 caacttcaac tgttattcgt aagctcaatg attttcactt taaacatgat ttttcgcgtc
      421 ttcctgagat tatgtcttgg gatgagtatg cttttacaaa gggaaagatg agcttcattg
      481 cgcaagattt tgaaaagctc gatatcatca ctgttcttga gggtagaaca caagctatca
      541 ttcgaaatca ctttcttcgc tacgatagag ttgtccgatg tcgcgtcaaa attattacta
      601 tggatatgtt tagtccttac tatgacttag ctagacaact tttcccgtgt gctaaaatcg
      661 tgttggatcg ctttcacatt gtacaacatc ttagccgtgc tatgagtcgt gtgcgtgttc
      721 aaatcatgaa tcaattggat cgaaagtctc atgaatacaa ggctatcaag cgctactgga
      781 agctcataca acaggatagt cgtaaactca gcgataaaca tttttatcgc cctacttttc
      841 gtatgcattt aaccaataaa gagattttt
//
LOCUS       DAVLBE010000117          791 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.117, whole genome shotgun sequence.
ACCESSION   DAVLBE010000117 DAVLBE010000000
VERSION     DAVLBE010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..791
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.117"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(282..452)
                     /locus_tag="VXB91_002022"
     CDS             complement(282..452)
                     /locus_tag="VXB91_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0471387.1"
                     /translation="MKKENEYVILTTASLGVMIGIVFAIFLDFPVEYGISLGLLNGIV
                     LGSLIVYKNNKN"
     gene            complement(465..>791)
                     /locus_tag="VXB91_002023"
     CDS             complement(465..>791)
                     /locus_tag="VXB91_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0471388.1"
                     /translation="NTIISEMGSNISGGQRQRIALARALINNPSIVILDEATSALDTI
                     NEERITKYIQSQGCTQIIVAHRLSTIKDADVIFVMKGGKIVESGNHKYLMDLGGEYYS
                     LYTKRK"
BASE COUNT          257 a          159 c          102 g          273 t
ORIGIN      
        1 caatgaaaat caaagagcaa actaggaagc gagccgcagg ctgtacttga gtacggtaaa
       61 gcaaagctga cgtggtttga agagattttc aaagagtatt aaacaaaaag aaaaaccgct
      121 actcctaaga atagcgattt aatcatgttt ttaagctact actgtagttg ctctattatt
      181 taagtgttat gaataacttc aatatcttta aagctttttg ttagatttat aatttcaact
      241 atagccatct ctactcctta gtttacagca aaaaattatg cttaattctt attgtttttg
      301 taaacaatca gcgaacccaa tactattcca ttcaacaagc ctaaagaaat accatattca
      361 actggaaaat ctaaaaaaat tgcaaacact attccaatca tcacccctag tgaggctgtt
      421 gttaaaatta catattcatt ttctttcttc attttcttta cacctcattt cctttttgta
      481 tataagctgt agtactctcc accaagatcc attaagtact tatgatttcc tgactcaaca
      541 atcttaccac ctttcattac aaaaataaca tccgcatcct taatcgttga caatctatga
      601 gctacaatta tttgagtaca gccctgactt tgtatatact ttgttattct ttcctcatta
      661 atagtgtcta atgcactagt tgcttcatct aaaattacaa tactaggatt atttattaat
      721 gcacgtgcca gtgctatccg ttgcctttgc ccacctgaaa tatttgaccc catctctgag
      781 atgatagtat t
//
LOCUS       DAVLBE010000118          772 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.118, whole genome shotgun sequence.
ACCESSION   DAVLBE010000118 DAVLBE010000000
VERSION     DAVLBE010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 772)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 772)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..772
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.118"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            82..561
                     /locus_tag="VXB91_002024"
     CDS             82..561
                     /locus_tag="VXB91_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEV0471389.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISR
                     EEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRRYDKEPYEEVGEISHRISEGGLW
                     LDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH"
     gene            656..727
                     /locus_tag="VXB91_002025"
     tRNA            656..727
                     /locus_tag="VXB91_002025"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:689..691,aa:Glu,seq:ttc)
BASE COUNT          292 a          105 c          181 g          194 t
ORIGIN      
        1 ggagctaaag ggaacagaat ggagaaaatg gaacaaatgt gttttctaat ctgttagact
       61 gtatctagaa aggggaaaat tatgattaaa gaattgtatg aagaagtcca agggactgtg
      121 tataagtgta gaaatgaata ttaccttcat ttatgggaat tatcggattg ggaccaagaa
      181 ggcatgctct gcttacatga attgattagt agagaagaag gactggtaga cgatattcca
      241 cgtttaagga aatatttcaa aaccaagttt cgaaatcgaa ttttagacta tatccgtaag
      301 caggaaagtc agaagcgtag atacgataaa gaaccctatg aagaagtggg tgagatcagt
      361 catcgtataa gtgagggggg tctctggcta gatgattatt atctctttca tgaaacacta
      421 agagattata gaaacaaaca aagtaaagag aaacaagaag aactagaacg cgtcttaagc
      481 aatgaacgat ttcgagggcg tcaaagagta ttaagagact tacgcattgt gtttaaggag
      541 tttactatcc gtacccacta gtaagtcatg caaaaaaaaa tgaaaaaaat tagaaaaagt
      601 agttgacaaa gtttgaaaag actgtataat agtaagagtt gaaaataaca actcaggtcc
      661 gttggtcaag gggttaagac accgcctttt cacggcggta acacgggttc gaatcccgta
      721 cggactatgg tatgttgcgt caggaccact tgatgaaaaa aagtttaaaa aa
//
LOCUS       DAVLBE010000119          635 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.119, whole genome shotgun sequence.
ACCESSION   DAVLBE010000119 DAVLBE010000000
VERSION     DAVLBE010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 635)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 635)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..635
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.119"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            194..412
                     /locus_tag="VXB91_002026"
     CDS             194..412
                     /locus_tag="VXB91_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001859328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HEV0471390.1"
                     /translation="MKKISVTVIGYFEINIDENITDILYVNGTAILYPYLRSIVSIVS
                     AIDSSEAMLLPTINVLELLDKSQPFEEE"
BASE COUNT          209 a           77 c          119 g          230 t
ORIGIN      
        1 tgcggctagt ttcctagttt gctctttggt tttcattgag tataacacat tgttagaagt
       61 tggtttaaat ttcctaatca gtttgttcac atttaccttc gatatattat atcccatagt
      121 taaggttggt catacagatg attatagcca tggagccgta aaacttagtg tttctttagt
      181 tgacaaagat gccatgaaaa aaatatctgt aactgtaata ggatattttg aaataaatat
      241 agatgaaaat atcaccgata ttctatacgt aaatggtact gctattcttt atccttattt
      301 acgttctatt gtttcaatag tttcggcaat tgatagcagt gaagcaatgt tgctacctac
      361 cattaatgtt ttagagttac tagataaatc tcaacctttt gaagaagaat aatttattag
      421 ctcactaaat tgagggtaag gaaaagtaaa agcagtaaga aaaatgtctt gcattataca
      481 gcaacttttt gggaatgagt agatggattg aataaaattt gattaagagt ggatgattta
      541 tctgtagatt attattggac agttagtctt gaagtagtct aagaattagg ttataatcag
      601 tagaagcctt gctaataatg aggaggttag tttat
//
LOCUS       DAVLBE010000120          629 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.120, whole genome shotgun sequence.
ACCESSION   DAVLBE010000120 DAVLBE010000000
VERSION     DAVLBE010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 629)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 629)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..629
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.120"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            <1..>629
                     /gene="phtB"
                     /locus_tag="VXB91_002027"
     CDS             <1..>629
                     /gene="phtB"
                     /locus_tag="VXB91_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtB"
                     /protein_id="HEV0471391.1"
                     /translation="LKDVSSDKVKLVDDILAFLAPIRHPERLGKPNAQITYTDDEIQV
                     AKLAGKYTTEDGYIFDPRDITSDEGDAYVTPHMTHSHWIKKDSLSEAERAAAQAYAKE
                     KGLTPPSTDHQDSGNTEAKGAEAIYNRVKAAKKVPLDRMPYNLQYTVEVKNGSLIIPH
                     YDHYHNIKFEWFDEGLYEAPKGYTLEDLLATVKYYVEHPNERPHSDNGF"
BASE COUNT          200 a          129 c          139 g          161 t
ORIGIN      
        1 actcaaggat gtctcaagtg ataaagtcaa gttagtggat gatattcttg ccttcttagc
       61 tccgattcgt catccagaac gtttaggaaa accaaatgcg caaattacct acactgatga
      121 tgagattcaa gtagccaagt tggcaggcaa gtacacaaca gaagacggtt atatctttga
      181 tcctcgtgat ataaccagtg atgaggggga tgcctatgta actccacata tgacccatag
      241 ccactggatt aaaaaagata gtttgtctga agctgagaga gcggcagccc aggcttatgc
      301 taaagagaaa ggtttgaccc ctccttcgac agaccatcag gattcaggaa atactgaggc
      361 aaaaggagca gaagctatct acaaccgcgt gaaagcagct aagaaggtgc cacttgatcg
      421 tatgccttac aatcttcaat atactgtaga agtcaaaaac ggtagtttaa tcatacctca
      481 ttatgaccat taccataaca tcaaatttga gtggtttgac gaaggccttt atgaggcacc
      541 taaggggtat actcttgagg atcttttggc gactgtcaag tactatgtcg aacatccaaa
      601 cgaacgtccg cattcagata atggttttg
//
LOCUS       DAVLBE010000121          527 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.121, whole genome shotgun sequence.
ACCESSION   DAVLBE010000121 DAVLBE010000000
VERSION     DAVLBE010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 527)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 527)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..527
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.121"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            1..527
                     /locus_tag="VXB91_002028"
                     /pseudo
     CDS             1..527
                     /locus_tag="VXB91_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT          179 a          100 c           97 g          151 t
ORIGIN      
        1 aactaccatc cactatgcgc tcaaagctat gggttacact cgaaaaaaag aaccacacct
       61 actatgaaca agacccagaa aaagtagcct tatttcttaa gaattttaat agtttaaagc
      121 acctagcacc tgtttagatt gacgaaacag gattcgatac ttatttttat cgagaatatg
      181 gtcgctcatt aaaaggtcag ttaataagag gcaaagtatc tggaagaaga tatcagagaa
      241 tttctttggt tgcaggtcta acaaatggtg agttaatcgc tccaatgact tacgaagaga
      301 cgatgacgag cgactttttt gaagcttggt ttcagaagtt tctcttacca acattaacca
      361 caccatcggt tattattatg gataatgcaa gattccatag aatgggtaag ttagaactct
      421 tgtgtgaaga gtttgggtat aactttttac ctcttcctcc ctactcacct gagtacaatc
      481 ctattgagaa aacatgggct catatcaaaa agcacctcaa aaaggta
//
LOCUS       DAVLBE010000122          456 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00047818
            SAMN33606698-rid17953323.denovo.122, whole genome shotgun sequence.
ACCESSION   DAVLBE010000122 DAVLBE010000000
VERSION     DAVLBE010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606698
            Sequence Read Archive: SRR23726127
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 456)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 456)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722004.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722004.1
            Genome Coverage       :: 354x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:44:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,029
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,865
            CDSs (with protein)               :: 1,865
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 60 of 117
            Pseudo Genes (incomplete)         :: 48 of 117
            Pseudo Genes (internal stop)      :: 40 of 117
            Pseudo Genes (multiple problems)  :: 27 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..456
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606698-rid17953323.denovo.122"
                     /strain="AUSMDU00047818"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            <1..>456
                     /locus_tag="VXB91_002029"
     CDS             <1..>456
                     /locus_tag="VXB91_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat-containing
                     protein"
                     /protein_id="HEV0471392.1"
                     /translation="KKVTININGLISKETVQKAVADNVKDSIDVPAAYLEKAKGEGPF
                     TAGVNHVIPYELFAGDGMLTRLLLKASDKAPWSDNGDAKNPALSPLGENVKTKGQYFY
                     QVALDGNVAGKEKQALIDQFRANGTQTYSATVNVYGNKDGKPDLDNIVAT"
BASE COUNT          158 a          104 c           95 g           99 t
ORIGIN      
        1 aaaaaagtca ctattaacat aaacggttta atttctaaag aaacagttca aaaagccgtt
       61 gcagacaacg ttaaagacag tatcgatgtt ccagcagcct acttagaaaa agccaagggt
      121 gaaggtccat tcacagcagg tgtcaaccat gtgattccat acgaactctt cgcaggtgat
      181 ggtatgttga ctcgtctctt gctcaaggca tctgacaagg caccatggtc agataacggc
      241 gacgctaaaa acccagccct atctccacta ggtgaaaacg tgaagaccaa aggtcaatac
      301 ttctatcaag tagccttgga cggaaatgta gctggcaaag aaaaacaagc gctcattgac
      361 cagttccgag caaatggtac tcaaacttac agcgctacag tcaatgtcta tggtaacaaa
      421 gacggtaaac cagacttgga caacatcgta gcaact
//
